Generation and characterization of Smac/DIABLO-deficient mice

Molecular and Cellular Biology

Volumn 22, Issue 10, 2002, Pages 3509-3517

  Okada, Hitoshi ^a   Suh, Woong Kyung ^a   Jin, Jianping ^a   Woo, Minna ^a   Du, Chunying ^a   Elia, Andrew ^a   Duncan, Gordon S ^a   Wakeham, Andrew ^a   Itie, Annick ^a   Lowe, Scott W ^a   Wang, Xiaodong ^a   Mak, Tak W ^a  

^a AMGEN INSTITUTE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CASPASE 3; FAS ANTIBODY; INHIBITOR OF APOPTOSIS PROTEIN; MEMBRANE PROTEIN; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CYTOSOL; EMBRYO; ENZYME ACTIVATION; ENZYME DEGRADATION; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION;

ANIMALS; ANTIBODIES; ANTIGENS, CD95; APOPTOSIS; B-LYMPHOCYTES; CARRIER PROTEINS; CASPASE 3; CASPASE 8; CASPASE 9; CASPASES; CELLS, CULTURED; EMBRYO; ENZYME ACTIVATION; GENE TARGETING; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, KNOCKOUT; MITOCHONDRIAL PROTEINS; STEM CELLS; SURVIVAL RATE; T-LYMPHOCYTES;

ANIMALIA; INTRACISTERNAL A-PARTICLES;

EID: 0036233590     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.22.10.3509-3517.2002     Document Type: Article

References (35)

1. Human ICE/CED-3 protease nomenclature
2. Structural and biochemical basis of apoptotic activation by Smac/DIABLO
3. Proteases to die for
4. IAP family proteins - Suppressors of apoptosis
5. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
6. Mechanisms and functions of cell death
7. Oncogene-dependent apoptosis in extracts from drug-resistant cells
8. Oncogene-dependent apoptosis is mediated by caspase 9
9. Induction of apoptosis by Drosophila reaper, hid and grim through inhibition of IAP function
10. Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts IAP-caspase interaction
11. Programmed cell death in animal development
12. Suppression of doxorubicin cardiotoxicity by overexpression of catalase in the heart of transgenic mice
13. Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
14. The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a Reaper-like motif
15. Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxieity by amyloid-beta
16. Hematopoiesis in the fetal liver is impaired by targeted mutagenesis of a gene encoding a non-DNA binding subunit of the transcription factor, polyomavirus enhancer binding protein 2/core binding factor
17. Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
18. p53AIPI, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53
19. AMLI(-/-) embryos do not express certain hematopoiesis-related gene transcripts including those of the PU.1 gene
20. Mouse models of cell death
21. Bc110 is a positive regulator of antigen receptor-induced activation of NF-kappaB and neural tube closure
22. Caspases: Intracellular signaling by protcolysis
23. Selective induction of p53 and chemosensitivity in RB-deficient cells by E1A mutants unable to bind the RB-related proteins
24. Molecular characterization of mitochondrial apoptosis-inducing factor
25. A serine protease, htra2, is released from the mitochondria and interacts with xiap, inducing cell death
26. Caspases: Enemies within
27. HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins
28. Inhibitor of apoptosis proteins and their relatives: IAPs and other BIRPs
29. Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins
30. Myc activates telomerase
31. In vivo evidence that caspase 3 is required for Fas-mediated apoptosis of hepatocytes
32. Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes
33. Structural basis of IAP recognition by Smac/DIABLO
34. Structural analysis of a functional DIAP1 fragment bound to grim and hid peptides
35. A novel negative selection for homologous recombinants using diphtheria toxin A fragment gene