Expression of Bcl-2 in adult human brain regions with special reference to neurodegenerative disorders

Journal of Neurochemistry

Volumn 69, Issue 1, 1997, Pages 223-231

  Vyas, Sheela ^a,d   Javoy Agid, France ^a   Herrero, María Trinidad ^c   Strada, Ornella ^a   Boissiere, Florence ^a   Hibner, Urzula ^b   Agid, Yves ^a  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^b INSTITUT DE GÉNÉTIQUE MOLÉCULAIRE DE MONTPELLIER   (France)

^c UNIVERSITY OF MURCIA   (Spain)

^d ICRP   (United Kingdom)

Author keywords

Alzheimer's disease; Apoptosis; Bcl 2 protooncogene; Human brain; Neurons; Parkinson's disease

Indexed keywords

ALZHEIMER DISEASE; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; GENE EXPRESSION REGULATION; HUMAN; HUMAN TISSUE; MOUSE; NERVE CELL DEGENERATION; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTO ONCOGENE; PYRAMIDAL NERVE CELL; SUBSTANTIA NIGRA;

ANIMALIA;

EID: 0030906885     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1997.69010223.x     Document Type: Article

References (51)

1. Agid Y. (1991) Parkinson's disease: pathophysiology. Lancet 337, 1321-1324.
2. Agid Y., Ruberg M., Javoy-Agid F., Hirsch E., Raisman-Vozari R., Vyas S., Faucheux B., Michel P., Kastner A., Blanchard V., Damier P., Villares J., and Zhang P. (1993) Are dopaminergic neurons selectively vulnerable to Parkinson's disease? Adv. Neurol. 60, 148-164.
3. Allsopp T. E., Wyatt S., Paterson H. F., and Davies A. M. (1993) The proto-oncogene bcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis. Cell 73, 295-307.
4. Anglade P., Vyas S., Javoy-Agid F., Herrero M. T., Michel P. P., Marquez J., Mouatt-Prigent A., Ruberg M., Hirsch E., and Agid Y. (1997) Apoptosis and autophagy in nigral neurons of patients with Parkinson's disease. Histol. Histopathol 12, 25-31.
5. Ausubel F. M. R., Brent R., Kingston R. E., Moore D. M., Seidman J. G., Smith J. A., and Struhl K. (1993) Current Protocols in Molecular Biology. John Wiley and Sons, New York.
6. Beal M. F. (1992) Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses? Ann. Neurol. 31, 119-130.
7. Bradford M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
8. Bredesen D. E. (1995) Neural apoptosis. Ann. Neurol. 38, 839-851.
9. Castren E., Ohga Y., Berzaghi M. P., Tzimagiorgise G., Thoenen H., and Lindholm M. (1994) bcl-2 messenger RNA is localized in neurons of the developing and adult rat brain. Neuroscience 61, 165-177.
10. Chomczynski P. and Sacchi N. (1984) Single step method of RNA isolation by acid guanidium thiocyanante-phenol-chloroform extraction. Ann. Biochem. 162, 156-159.
11. Civelli O., Birnerg N., and Herbert E. (1982) Detection and quantitation of pro-opiomelanocortin mRNA in pituitary and brain tissues from different species. J. Biol. Chem. 257, 6783-6787.
12. Cleary M. L., Smith S. D., and Sklar J. (1986) Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14; 18) translocation. Cell 47, 19-28.
13. Cotman C. W. and Anderson A. J. (1995) A potential role for apoptosis in neurodegenerative and Alzheimer's disease. Mol. Neurobiol. 10, 19-45.
14. Dubois-Dauphin M., Frankowski H., Tsujimoto Y., Huarte J., and Martinou J.-C. (1994) Neonatal motoneurons overexpressing the bcl-2 protooncogene in transgenic mice are protected from axotomy-induced cell death. Proc. Natl. Acad. Sci. USA 91, 3309-3313.
15. Garcia I., Martinou I., Tsujimoto Y., and Martinou J.-C. (1992) Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene. Science 258, 302-304.
16. Hengartner M. O. and Horvitz H. R. (1994a) The ins and outs of programmed cell death during C. elegans development. Philos. Trans. R. Soc. Lond. [Biol.] 345, 243-246.
17. Hengartner M. O. and Horvitz H. R. (1994b) C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2. Cell 76, 665-676.
18. Hennet T., Bertoni G., Richter C., and Peterhans E. (1993) Expression of Bcl-2 protein enhances the survival of mouse fibrosarcoid cells in tumor necrosis factor-mediated cytotoxicity. Cancer Res. 53, 1456-1460.
19. Hockenberry D. M., Zutter M., Hickey W., Moon N., and Korsmeyer S. J. (1991) Bcl-2 protein is topographically restricted in tissues characterized by apoptotic cell death. Proc. Natl. Acad. Sci. USA 88, 6961-6965.
20. Hockenberry D. M., Oltvai Z. N., Yin X.-M., Milliman C. L., and Korsmeyer S. J. (1993) Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 75, 241-251.
21. Jacobson M. D. and Raff M. C. (1995) Programmed cell death and Bcl-2 protection in very low oxygen. Nature 374, 814-816.
22. Javoy-Agid F., Hirsch E., Dumas S., Duyckaerts C., Mallet J., and Agid Y. (1990) Decreased tyrosine hydroxylase mRNA in the surviving dopamine neurons in Parkinson's disease. Neuroscience 38, 245-253.
23. Kane D. J., Sarafian T. A., Anton R., Hahn H., Butler Gralla E., Selverstone Valentine J., Ord T., and Bredesen D. E. (1993) Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species. Science 262, 1274-1277.
24. Kerr J. F. R., Wyellie A. H., and Currie A. R. (1972) Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer 26, 239-257.
25. Korsmeyer S. J. (1995) Regulators of cell death. Trends Genet. 11, 101-104.
26. LaFerla F. M., Tinkle B. T., Bieberich C. J., Haudenschild C. C., and Jay G. (1995) The Alzheimer's Aβ peptide induces neurodegeneration and apoptotic cell death in transgenic mice. Nat. Genet. 9, 21-30.
27. LeBlanc A. (1994) The role of β-amyloid peptide in Alzheimer's disease. Metab. Brain Dis. 9, 3-31.
28. LeBrun D. P., Warnke R. A., and Cleary M. L. (1993) Expression of bcl-2 in fetal tissues suggests a role in morphogenesis. Am. J. Pathol. 142, 743-753.
29. Lindsay R. M. (1994) Neurotrophic growth factors and neurodegenerative diseases: therapeutic potential of the neurotrophins and ciliary neurotrophic factor. Neurobiol Aging 15, 249-251.
30. Loo D. T., Copani A., Pike C. J., Whittemore E. R., Walencewicz A. J., and Cotman C. W. (1993) Apoptosis is induced by β-amyloid in cultured central nervous system neurons. Proc. Natl. Acad. Sci. USA 90, 7951-7955.
31. Martinou J.-C., Dubois-Dauphin M., Staple J. K., Rodriguez I., Frankowski H., Missotten M., Albertini P., Talabot D., Catsicas S., Pietra C., and Huarte J. (1994) Overexpression of Bcl-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia. Neuron 13, 1017-1030.
32. Merry D. E., Veis D. J., Hickey W. F., and Korsmeyer S. J. (1994) Bcl-2 protein expression is widespread in the developing nervous system and retained in the adult PNS. Development 120, 301-311.
33. Negrini M., Sillini E., Kozak C., Tsujimoto Y., and Croce C. M. (1987) Molecular analysis of mbcl-2: structure and expression of the murine gene homologous to the human gene involved in follicular lymphoma. Cell 49, 455-463.
34. Oltvai Z. N., Milliman C. L., and Korsmeyer S. J. (1993) Bcl-2 heterodimerizes in vivo with a conserved homolog Bax, that accelerates programmed cell death. Cell 74, 609-619.
35. Pezella F., Tse A. G. D., Cordell J. L., Pulford K. A. F., Gatter K. C., and Mason D. Y. (1990) Expression of the bcl-2 oncogene protein is not specific for the 14; 18 chromosomal translocation. Am. J. Pathol 137, 225-232.
36. Portera-Cailliau C., Hedreen J. C., Price D. L., and Koliatsos V. E. (1995) Evidence for apoptotic cell death in Huntington's disease and excitotoxic animal models. J. Neurosci. 15, 3775-3787.
37. Prehn J. H. M., Bindokas V. P., Marcuccilli C. J., Krajewski S., Reed J. C., and Miller R. J. (1994) Regulation of neuronal Bcl-2 protein expression and calcium homeostasis by transforming growth factor type β confers wide-ranging protection on rat hippocampal neurons. Proc. Natl. Acad. Sci. USA 91, 12599-12603.
38. Saper C. B., German D. C., and White C. L. (1985) Neuronal pathology in the nucleus basalis and associated cell groups in senile demenlia of the Alzheimer's type: possible role in cell loss. Neurology 35, 1089-1095.
39. Shimizu S., Eguchi Y., Kosaka H., Kamiike W., Matsuda H., and Tsujimoto Y. (1995) Prevention of hypoxia-induced cell death by Bcl-2 and Bcl-xL. Nature 374, 811-813.
40. Smith M. A., Sayre L. M., Monnier V. M., and Perry G. (1995) Radical AGEing in Alzheimer's disease. Trends Neurosci. 18, 172-176.
41. Strada O., Vyas S., Hirsch E. C., Ruberg M., Brice A., Agid Y., and Javoy-Agid F. (1992) Decreased choline acetyltransferase mRNA expression in the nucleus basalis of Meynert in Alzheimer disease: an in situ hybridization study. Proc. Natl. Acad. Sci. USA 89, 9549-9553.
42. Su J. H., Anderson A. J., Cumming B. J., and Cotman C. W. (1994) Immunocytochemical evidence for apoptosis in Alzheimer's disease. Neuroreport 5, 2529-2533.
43. Thompson C. B. (1995) Apoptosis in the pathogenesis and treatment of disease. Science 265, 1456-1462.
44. Tsujimoto Y. and Croce C. M. (1986) Analysis of the structure, transcripts, and protein products of bcl-2, the gene involved in human follicular lymphoma. Proc. Natl. Acad. Sci. USA 83, 5214-5218.
45. Tsujimoto Y., Finger L. R., Yunis J. J., Nowell P. C., and Croce C. M. (1984) Cloning of the chromosome breakpoint of neoplastic B-cells with t(14;18) chromosome translocation. Science 226, 1097-1099.
46. Uhl G. R., Walther D., Mash D., Faucheux B., and Javoy-Agid F. (1994) Dopamine transporter messenger RNA in Parkinson's disease and control substantia nigra neurons. Ann. Neurol. 35, 494-498.
47. Veis Novack D. and Korsmeyer S. J. (1994) Bcl-2 protein expression during murine development. Am. J. Pathol. 145, 61-73.
48. Wang L., Miura M., Bergeron L., Zhu H., and Yuan J. (1994) Ich1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death. Cell 78, 739-750.
49. Yin X.-M., Oltvai Z. N., and Korsmeyer S. (1994) BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax. Nature 369, 321-323.
50. Zhang P., Anglade P., Hirsch E. C., Javoy-Agid F., and Agid Y. (1994) Distribution of manganese-dependent superoxide dismutase in the human brain. Neuroscience 61, 317-330.
51. Zhong L.-T., Sarafian T., Kane D. J., Charles A. C., Mah S. P., Edwards R. H., and Bredesen D. E. (1993) Bcl-2 inhibits death of central neural cells induced by multiple agents. Proc. Natl. Acad. Sci. USA 90, 4533-4537.