Cell biology: PUMA couples the nuclear and cytoplasmic proapoptotic function of p53

Science

Volumn 309, Issue 5741, 2005, Pages 1732-1735

  Chipuk, Jerry E ^a,c   Bouchier Hayes, Lisa ^a   Kuwana, Tomomi ^a,b   Newmeyer, Donald D ^a   Green, Douglas R ^a,c  

^a LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENES; PROTEINS; TUMORS;

CYTOPLASMIC PROAPOPTOTIC FUNCTIONS; MITOCHONDRIA; PERMEABILIZATION; PUMA COUPLES;

CELLS;

BH3 PROTEIN; MUTANT PROTEIN; P53 UPREGULATED MODIFIER OF APOPTOSIS; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN P53; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; BBC3 PROTEIN, HUMAN; BCL2L1 PROTEIN, HUMAN; BCL2L1 PROTEIN, MOUSE; ONCOPROTEIN; PROTEIN BCL X; PUMA PROTEIN, MOUSE; RECOMBINANT PROTEIN; TUMOR SUPPRESSOR PROTEIN;

BIOLOGY;

APOPTOSIS; ARTICLE; CELL NUCLEUS; CELL PERMEABILIZATION; CYTOPLASM; GENE EXPRESSION REGULATION; GENOTOXICITY; HUMAN; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; TIGHT JUNCTION; TUMOR SUPPRESSOR GENE; ANIMAL; BIOLOGICAL MODEL; C57BL MOUSE; CELL CULTURE; CHEMISTRY; DNA DAMAGE; IMMUNOPRECIPITATION; METABOLISM; MOUSE; PERMEABILITY; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; TUMOR CELL LINE; ULTRAVIOLET RADIATION;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; CELL LINE, TUMOR; CELL NUCLEUS; CELLS, CULTURED; CYTOPLASM; DNA DAMAGE; GENE EXPRESSION REGULATION; HUMANS; IMMUNOPRECIPITATION; MICE; MICE, INBRED C57BL; MITOCHONDRIA; MODELS, BIOLOGICAL; PERMEABILITY; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RECOMBINANT PROTEINS; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS; ULTRAVIOLET RAYS;

EID: 24644436766     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1114297     Document Type: Article

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