Paraquat neurotoxicity is mediated by a Bak-dependent mechanism

Journal of Biological Chemistry

Volumn 283, Issue 6, 2008, Pages 3357-3364

  Fei, Qingyan ^a   McCormack, Alison L ^b   Di Monte, Donato A ^b   Ethell, Douglas W ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b PARKINSON S INSTITUTE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGGLOMERATION; AMINO ACIDS; CELL DEATH; CHEMICAL ACTIVATION; HERBICIDES; NUCLEIC ACIDS; POLYMERS; RNA;

APOPTOSIS; BIO-CHEMICALS; CASPASE INHIBITORS; CASPASE-3; CYCLOHEXIMIDE; CYTOCHROME C; DOPAMINERGIC NEURONS; FAMILY MEMBERS; NEUROTOXICITY; NUCLEAR MORPHOLOGIES; OVEREXPRESSION; PARKINSON DISEASES; PATHOLOGICAL FEATURES; POLYMERASE CLEAVAGES; SMALL INTERFERING RNAS; SUBSTANTIA NIGRA; SYNUCLEIN AGGREGATIONS; TERMINAL KINASES; TYROSINE HYDROXYLASE;

NEURONS;

CASPASE 3; CASPASE INHIBITOR; CYCLOHEXIMIDE; CYTOCHROME C; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PARAQUAT; PROTEIN BAK; PROTEIN BCL 2; PROTEIN BID; PROTEIN NOXA; SMALL INTERFERING RNA; BAK1 PROTEIN, HUMAN; HERBICIDE; PROTEIN SYNTHESIS INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MOUSE; NERVE CELL; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; C57BL MOUSE; CELL SURVIVAL; GENE EXPRESSION REGULATION; METABOLISM; MOUSE MUTANT; OXIDATIVE STRESS; PARKINSON DISEASE;

MUS;

ANIMALS; APOPTOSIS; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; CASPASE 3; CELL SURVIVAL; CYCLOHEXIMIDE; GENE EXPRESSION REGULATION; HERBICIDES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OXIDATIVE STRESS; PARAQUAT; PARKINSON DISEASE; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN SYNTHESIS INHIBITORS; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 41249098254     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M708451200     Document Type: Article

References (49)

1. Nakamura, S., and Lipton, S. A. (2007) Cell Mol. Life Sci. 64, 1609-1620
2. Mattson, M. P., and Magnus, T. (2006) Nat. Rev. Neurosci. 7, 278-294
3. Hertzman, C., Wiens, M., Bowering, D., Snow, B., and Calne, D. (1990) Am. J. Ind. Med. 17, 349-355
4. Jimenez-Jimenez, F. J., Fernandez-Calle, P., Martinez-Vanaclocha, M., Herrero, E., Molina, J. A., Vazquez, A., and Codoceo, R. (1992) J. Neurol. Sci. 112, 30-33
5. Semchuk, K. M., Love, E. J., and Lee, R. G. (1992) Neurology 42, 1328-1335
6. Hubble, J. P., Cao, T., Hassanein, R. E., Neuberger, J. S., and Koller, W. C. (1993) Neurology 43, 1693-1697
7. Gorell, J. M., Johnson, C. C., Rybicki, B. A., Peterson, E. L., and Richardson, R. J. (1998) Neurology 50, 1346-1350
8. Stephenson, J. (2000) JAMA 283, 3055-3056
9. Di Monte, D. A. (2003) Lancet Neurol. 2, 531-538
10. Liou, H. H., Tsai, M. C., Chen, C. J., Jeng, J. S., Chang, Y. C., Chen, S. Y., and Chen, R. C. (1997) Neurology 48, 1583-1588
11. McCormack, A. L., Thiruchelvam, M., Manning-Bog, A. B., Thiffault, C., Langston, J. W., Cory-Slechta, D. A., and Di Monte, D. A. (2002) Neurobiol. Dis. 10, 119-127
12. Manning-Bog, A. B., McCormack, A. L., Purisai, M. G., Bolin, L. M., and Di Monte, D. A. (2003) J. Neurosci. 23, 3095-3099
13. Bredesen, D. E., Rao, R. V., and Mehlen, P. (2006) Nature 443, 796-802
14. Buss, R. R., Sun, W., and Oppenheim, R. W. (2006) Annu. Rev. Neurosci. 29, 1-35
15. Edinger, A. L., and Thompson, C. B. (2004) Curr. Opin. Cell Biol. 16, 663-669
16. Jiang, X., and Wang, X. (2004) Annu. Rev. Biochem. 73, 87-106
17. Green, D. R. (2007) Cancer Cell 12, 97-99
18. van Delft, M. F., and Huang, D. C. (2006) Cell Res. 16, 203-213
19. Goldman, S. M., Tanner, C. M., Oakes, D., Bhudhikanok, G. S., Gupta, A., and Langston, J. W. (2006) Ann. Neurol. 60, 65-72
20. Shimizu, K., Ohtaki, K., Matsubara, K., Aoyama, K., Uezono, T., Saito, O., Suno, M., Ogawa, K., Hayase, N., Kimura, K., and Shiono, H. (2001) Brain Res. 906, 135-142
21. Bharath, S., Hsu, M., Kaur, D., Rajagopalan, S., and Andersen, J. K. (2002) Biochem. Pharmacol. 64, 1037-1048
22. Filomeni, G., and Ciriolo, M. R. (2006) Antioxid. Redox Signal. 8, 2187-2192
23. Peng, J., Stevenson, F. F., Doctrow, S. R., and Andersen, J. K. (2005) J. Biol. Chem. 280, 29194-29198
24. Peng, J., Peng, L., Stevenson, F. F., Doctrow, S. R., and Andersen, J. K. (2007) J. Neurosci. 27, 6914-6922
25. McCormack, A. L., Atienza, J. G., Langston, J. W., and Di Monte, D. A. (2006) Neuroscience 141, 929-937
26. Peng, J., Mao, X. O., Stevenson, F. F., Hsu, M., and Andersen, J. K. (2004) J. Biol. Chem. 279, 32626-32632
27. Ethell, D. W., and Green, D. R. (2001) in Apoptosis Techniques and Protocols (LeBlanc, A. C., ed) 2nd Ed., pp. 21-34, Humana Press, New York
28. Yuan, B. B., Latek, R., Hossbach, M., Tuschl, T., and Lewitter, F. (2004) Nucleic Acids Res. 32, W130-W133
29. McCormack, A. L., and Di Monte, D. A. (2003) J. Neurochem. 85, 82-86
30. Gundersen, H. J., and Jensen, E. B. (1987) J. Micrsocopy 147, 229-263
31. Waterhouse, N. J., Goldstein, J. C., von Ahsen, O., Schuler, M., Newmeyer, D. D., and Green, D. R. (2001) J. Cell Biol. 153, 319-328
32. Wei, M. C., Zong, W. X., Cheng, E. H., Lindsten, T., Panoutsakopoulou, V., Ross, A. J., Roth, K. A., MacGregor, G. R., Thompson, C. B., and Korsmeyer, S. J. (2001) Science 292, 727-730
33. Ruiz-Vela, A., Opferman, J. T., Cheng, E. H., and Korsmeyer, S. J. (2005) EMBO Rep. 6, 379-385
34. Willis, S. N., Chen, L., Dewson, G., Wei, A., Naik, E., Fletcher, J. I., Adams, J. M., and Huang, D. C. (2005) Genes Dev. 19, 1294-1305
35. Willis, S. N., Fletcher, J. I., Kaufmann, T., van Delft, M. F., Chen, L., Czabotar, P. E., Ierino, H., Lee, E. F., Fairlie, W. D., Bouillet, P., Strasser, A., Kluck, R. M., Adams, J. M., and Huang, D. C. (2007) Science 315, 856-859
36. Eggert, A., Grotzer, M. A., Zuzak, T. J., Wiewrodt, B. R., Ho, R., Ikegaki, N., and Brodeur, G. M. (2001) Cancer Res. 61, 1314-1319
37. Casciano, I., Banelli, B., Croce, M., De Ambrosis, A., di Vinci, A., Gelv, iI., Pagnan, G., Brignole, C., Allemanni, G., Ferrini, S., Ponzoni, M., and Romani, M. (2004) Ann. N. Y. Acad. Sci. 1028, 157-167
38. Vila, M., Jackson-Lewis, V., Vukosavic, S., Djaldetti, R., Liberatore, G., Offen, D., Kosmeyer, S. J., and Przedborski, S. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 2837-2842
39. Ramachandiran, S., Hansen, J. M., Jones, D. P., Richardson, J. R., and Miller, G. W. (2007) Toxicol. Sci. 95, 163-171
40. Sowter, H. M., Ratcliffe, P. J., Watson, P., Greenberg, A. H., and Harris, A. L. (2001) Cancer Res. 61, 6669-6673
41. Kim, J. Y., Ahn, H. J., Ryu, J. H., Suk, K., and Park, J. H. (2004) J. Exp. Med. 19, 113-124
42. Langston, J. W., Ballard, P., Tetrud, J. W., and Irwin, I. (1983) Science 219, 979-980
43. Nicklas, W. J., Vyas, I., and Heikkila, R. E. (1985) Life Sci. 36, 2503-2508
44. Gainetdinov, R. R., Fumagalli, F., Jones, S. R., and Caron, M. G. (1997) J. Neurochem. 69, 1322-1325
45. Richardson, J. R., Quan, Y., Sherer, T. B., Greenamyre, J. T., and Miller, G. W. (2005) Toxicol. Sci. 88, 193-201
46. McCormack, A. L., Atienza, J. G., Johnston, L. C., Andersen, J. K., Vu, S., and Di Monte, D. A. (2005) J. Neurochem. 93, 1030-1037
47. Kim, J. Y., Ahn, H. J., Ryu, J. H., Suk, K., and Park, J. H. (2004) J. Exp. Med. 199, 113-124
48. Semenza, G. L. (2001) Curr. Opin. Cell Biol. 13, 167-171
49. Bower, J. H., Maraganore, D. M., Peterson, B. J., McDonnell, S. K., Ahlskog, J. E., and Rocca, W. A. (2003) Neurology 60, 1610-1615