Cyclin-dependent kinase 5 is a mediator of dopaminergic neuron loss in a mouse model of Parkinson's disease

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 23, 2003, Pages 13650-13655

  Smith, Patrice D ^a   Crocker, Stephen J ^a   Jackson Lewis, Vernice ^b   Jordan Sciutto, Kelly L ^d   Hayley, Shawn ^a   Mount, Matthew P ^a   O'Hare, Michael J ^a   Callaghan, Steven ^a   Slack, Ruth S ^a   Przedborski, Serge ^b   Anisman, Hymie ^c   Park, David S ^a  

^a OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^b Och Spine at New York Presbyterian Hospitals   (United States)

^c CARLETON UNIVERSITY   (Canada)

^d UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

1 methyl 4 phenyl 1,2,3,6 tetrahydropyridine; Neurodegeneration

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; CYCLIN DEPENDENT KINASE 5; CYCLIN DEPENDENT KINASE INHIBITOR; FLAVOPIRIDOL; REGULATOR PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL LOSS; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; DOPAMINERGIC SYSTEM; DRUG MECHANISM; ENZYME INHIBITION; LOCOMOTION; MALE; MOUSE; NERVE DEGENERATION; NEUROMODULATION; NEUROPATHOLOGY; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; ADENOVIRIDAE; ANIMALS; BLOTTING, WESTERN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYCLIN-DEPENDENT KINASE 5; CYCLIN-DEPENDENT KINASES; DISEASE MODELS, ANIMAL; DOPAMINE; DOPAMINE AGENTS; FLAVONOIDS; GENES, DOMINANT; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED C57BL; NEURONS; PARKINSON DISEASE; PIPERIDINES; TIME FACTORS;

ANIMALIA;

EID: 0344823864     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.2232515100     Document Type: Article

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