PINK1 is selectively stabilized on impaired mitochondria to activate Parkin

PLoS Biology

Volumn 8, Issue 1, 2010, Pages

  Narendra, Derek P ^a   Jin, Seok Min ^a   Tanaka, Atsushi ^a   Suen, Der Fen ^a   Gautier, Clement A ^b   Shen, Jie ^b   Cookson, Mark R ^c   Youle, Richard J ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL ENZYME; PARKIN; PINK1 ENZYME; PROTEINASE; THREONINE; UNCLASSIFIED DRUG; METALLOPROTEINASE; PROTEIN KINASE; PTEN INDUCED PUTATIVE KINASE; PTEN-INDUCED PUTATIVE KINASE; UBIQUITIN PROTEIN LIGASE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DEPOLARIZATION; DROSOPHILA MELANOGASTER; ENZYME DEGRADATION; GENETIC EPISTASIS; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN STABILITY; ANIMAL; BIOLOGICAL MODEL; GENETICS; HELA CELL; METABOLISM; MITOCHONDRIAL MEMBRANE; MOUSE; PARKINSON DISEASE; PHYSIOLOGY; RAT;

DROSOPHILA MELANOGASTER;

ANIMALS; HELA CELLS; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; METALLOPROTEASES; MICE; MITOCHONDRIA; MITOCHONDRIAL MEMBRANES; MODELS, BIOLOGICAL; PARKINSON DISEASE; PROTEIN KINASES; RATS; UBIQUITIN-PROTEIN LIGASES;

EID: 75749156257     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.1000298     Document Type: Article

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