-
2
-
-
36949007646
-
Intracellular NOD-like receptors in innate immunity, infection and disease
-
Franchi L, et al. Intracellular NOD-like receptors in innate immunity, infection and disease. Cell Microbiol 2008 10 : 1 8.
-
(2008)
Cell Microbiol
, vol.10
, pp. 1-8
-
-
Franchi, L.1
-
3
-
-
48549102504
-
NOD-like receptors (NLRs): Bona fide intracellular microbial sensors
-
Shaw MH, Reimer T, Kim YG, Nunez G. NOD-like receptors (NLRs): bona fide intracellular microbial sensors. Curr Opin Immunol 2008 20 : 377 382.
-
(2008)
Curr Opin Immunol
, vol.20
, pp. 377-382
-
-
Shaw, M.H.1
Reimer, T.2
Kim, Y.G.3
Nunez, G.4
-
4
-
-
33846319348
-
The innate signaling of dangers and the dangers of innate signaling
-
Sansonetti PJ. The innate signaling of dangers and the dangers of innate signaling. Nat Immunol 2006 7 : 1237 1242.
-
(2006)
Nat Immunol
, vol.7
, pp. 1237-1242
-
-
Sansonetti, P.J.1
-
5
-
-
32944464648
-
Pathogen recognition and innate immunity
-
Akira S, Uematsu S, Takeuchi O. Pathogen recognition and innate immunity. Cell 2006 124 : 783 801.
-
(2006)
Cell
, vol.124
, pp. 783-801
-
-
Akira, S.1
Uematsu, S.2
Takeuchi, O.3
-
6
-
-
34447505084
-
Toll-like receptors and type I interferons
-
Uematsu S, Akira S. Toll-like receptors and type I interferons. J Biol Chem 2007 282 : 15319 15323.
-
(2007)
J Biol Chem
, vol.282
, pp. 15319-15323
-
-
Uematsu, S.1
Akira, S.2
-
7
-
-
12444341944
-
Toll-like receptors in innate immunity
-
Takeda K, Akira S. Toll-like receptors in innate immunity. Int Immunol 2005 17 : 1 14.
-
(2005)
Int Immunol
, vol.17
, pp. 1-14
-
-
Takeda, K.1
Akira, S.2
-
8
-
-
31344461659
-
Innate immune recognition of viral infection
-
Kawai T, Akira S. Innate immune recognition of viral infection. Nat Immunol 2006 7 : 131 137.
-
(2006)
Nat Immunol
, vol.7
, pp. 131-137
-
-
Kawai, T.1
Akira, S.2
-
9
-
-
44649119259
-
Regulation of mitochondrial antiviral signaling pathways
-
Moore CB, Ting JP. Regulation of mitochondrial antiviral signaling pathways. Immunity 2008 28 : 735 739.
-
(2008)
Immunity
, vol.28
, pp. 735-739
-
-
Moore, C.B.1
Ting, J.P.2
-
10
-
-
33751100626
-
The plant immune system
-
Jones JD, Dangl JL. The plant immune system. Nature 2006 444 : 323 329.
-
(2006)
Nature
, vol.444
, pp. 323-329
-
-
Jones, J.D.1
Dangl, J.L.2
-
11
-
-
32944479048
-
Host-microbe interactions: Shaping the evolution of the plant immune response
-
Chisholm ST, Coaker G, Day B, Staskawicz BJ. Host-microbe interactions: shaping the evolution of the plant immune response. Cell 2006 124 : 803 814.
-
(2006)
Cell
, vol.124
, pp. 803-814
-
-
Chisholm, S.T.1
Coaker, G.2
Day, B.3
Staskawicz, B.J.4
-
12
-
-
33751549306
-
The immune gene repertoire encoded in the purple sea urchin genome
-
Hibino T, et al. The immune gene repertoire encoded in the purple sea urchin genome. Dev Biol 2006 300 : 349 365.
-
(2006)
Dev Biol
, vol.300
, pp. 349-365
-
-
Hibino, T.1
-
14
-
-
2342583513
-
Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition
-
Tanabe T, et al. Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition. EMBO J 2004 23 : 1587 1597.
-
(2004)
EMBO J
, vol.23
, pp. 1587-1597
-
-
Tanabe, T.1
-
15
-
-
40749132603
-
ATP binding by monarch-1/NLRP12 is critical for its inhibitory function
-
Ye Z, Lich JD, Moore CB, Duncan JA, Williams KL, Ting JP. ATP binding by monarch-1/NLRP12 is critical for its inhibitory function. Mol Cell Biol 2008 28 : 1841 1850.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 1841-1850
-
-
Ye, Z.1
Lich, J.D.2
Moore, C.B.3
Duncan, J.A.4
Williams, K.L.5
Ting, J.P.6
-
16
-
-
34249941913
-
Cryopyrin/NALP3 binds ATP/dATP, is an ATPase, and requires ATP binding to mediate inflammatory signaling
-
Duncan JA, et al. Cryopyrin/NALP3 binds ATP/dATP, is an ATPase, and requires ATP binding to mediate inflammatory signaling. Proc Natl Acad Sci USA 2007 104 : 8041 8046.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 8041-8046
-
-
Duncan, J.A.1
-
17
-
-
40449140937
-
The NLR gene family: A standard nomenclature
-
Ting JP, et al. The NLR gene family: a standard nomenclature. Immunity 2008 28 : 285 287.
-
(2008)
Immunity
, vol.28
, pp. 285-287
-
-
Ting, J.P.1
-
18
-
-
0038624558
-
NODs: Intracellular proteins involved in inflammation and apoptosis
-
Inohara N, Nunez G. NODs: intracellular proteins involved in inflammation and apoptosis. Nat Rev Immunol 2003 3 : 371 382.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 371-382
-
-
Inohara, N.1
Nunez, G.2
-
19
-
-
17644366913
-
NOD-LRR proteins: Role in host-microbial interactions and inflammatory disease
-
Inohara N, Chamaillard M, McDonald C, Nunez G. NOD-LRR proteins: role in host-microbial interactions and inflammatory disease. Annu Rev Biochem 2005 74 : 355 383.
-
(2005)
Annu Rev Biochem
, vol.74
, pp. 355-383
-
-
Inohara, N.1
Chamaillard, M.2
McDonald, C.3
Nunez, G.4
-
20
-
-
40249111682
-
NLRX1 is a mitochondrial NOD-like receptor that amplifies NF-kappaB and JNK pathways by inducing reactive oxygen species production
-
Tattoli I, et al. NLRX1 is a mitochondrial NOD-like receptor that amplifies NF-kappaB and JNK pathways by inducing reactive oxygen species production. EMBO Rep 2008 9 : 293 300.
-
(2008)
EMBO Rep
, vol.9
, pp. 293-300
-
-
Tattoli, I.1
-
21
-
-
38749097018
-
NLRX1 is a regulator of mitochondrial antiviral immunity
-
Moore CB, et al. NLRX1 is a regulator of mitochondrial antiviral immunity. Nature 2008 451 : 573 577.
-
(2008)
Nature
, vol.451
, pp. 573-577
-
-
Moore, C.B.1
-
22
-
-
0033591330
-
Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaB
-
Inohara N, et al. Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaB. J Biol Chem 1999 274 : 14560 14567.
-
(1999)
J Biol Chem
, vol.274
, pp. 14560-14567
-
-
Inohara, N.1
-
23
-
-
0035895992
-
Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB
-
Ogura Y, Inohara N, Benito A, Chen FF, Yamaoka S, Nunez G. Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB. J Biol Chem 2001 276 : 4812 4818.
-
(2001)
J Biol Chem
, vol.276
, pp. 4812-4818
-
-
Ogura, Y.1
Inohara, N.2
Benito, A.3
Chen, F.F.4
Yamaoka, S.5
Nunez, G.6
-
24
-
-
28444471235
-
Synergistic effect of Nod1 and Nod2 agonists with toll-like receptor agonists on human dendritic cells to generate interleukin-12 and T helper type 1 cells
-
Tada H, Aiba S, Shibata K, Ohteki T, Takada H. Synergistic effect of Nod1 and Nod2 agonists with toll-like receptor agonists on human dendritic cells to generate interleukin-12 and T helper type 1 cells. Infect Immun 2005 73 : 7967 7976.
-
(2005)
Infect Immun
, vol.73
, pp. 7967-7976
-
-
Tada, H.1
Aiba, S.2
Shibata, K.3
Ohteki, T.4
Takada, H.5
-
25
-
-
10744222688
-
Expression of NOD2 in Paneth cells: A possible link to Crohn's ileitis
-
Ogura Y, et al. Expression of NOD2 in Paneth cells: a possible link to Crohn's ileitis. Gut 2003 52 : 1591 1597.
-
(2003)
Gut
, vol.52
, pp. 1591-1597
-
-
Ogura, Y.1
-
26
-
-
33644849605
-
NOD2/CARD15 mediates induction of the antimicrobial peptide human beta-defensin-2
-
Voss E, Wehkamp J, Wehkamp K, Stange EF, Schroder JM, Harder J. NOD2/CARD15 mediates induction of the antimicrobial peptide human beta-defensin-2. J Biol Chem 2006 281 : 2005 2011.
-
(2006)
J Biol Chem
, vol.281
, pp. 2005-2011
-
-
Voss, E.1
Wehkamp, J.2
Wehkamp, K.3
Stange, E.F.4
Schroder, J.M.5
Harder, J.6
-
27
-
-
0037380969
-
CARD15/NOD2 functions as an antibacterial factor in human intestinal epithelial cells
-
Hisamatsu T, Suzuki M, Reinecker HC, Nadeau WJ, McCormick BA, Podolsky DK. CARD15/NOD2 functions as an antibacterial factor in human intestinal epithelial cells. Gastroenterology 2003 124 : 993 1000.
-
(2003)
Gastroenterology
, vol.124
, pp. 993-1000
-
-
Hisamatsu, T.1
Suzuki, M.2
Reinecker, H.C.3
Nadeau, W.J.4
McCormick, B.A.5
Podolsky, D.K.6
-
28
-
-
34247239745
-
Various human epithelial cells express functional Toll-like receptors, NOD1 and NOD2 to produce anti-microbial peptides, but not proinflammatory cytokines
-
Uehara A, Fujimoto Y, Fukase K, Takada H. Various human epithelial cells express functional Toll-like receptors, NOD1 and NOD2 to produce anti-microbial peptides, but not proinflammatory cytokines. Mol Immunol 2007 44 : 3100 3111.
-
(2007)
Mol Immunol
, vol.44
, pp. 3100-3111
-
-
Uehara, A.1
Fujimoto, Y.2
Fukase, K.3
Takada, H.4
-
29
-
-
20244387428
-
Chemically synthesized pathogen-associated molecular patterns increase the expression of peptidoglycan recognition proteins via toll-like receptors, NOD1 and NOD2 in human oral epithelial cells
-
Uehara A, et al. Chemically synthesized pathogen-associated molecular patterns increase the expression of peptidoglycan recognition proteins via toll-like receptors, NOD1 and NOD2 in human oral epithelial cells. Cell Microbiol 2005 7 : 675 686.
-
(2005)
Cell Microbiol
, vol.7
, pp. 675-686
-
-
Uehara, A.1
-
30
-
-
38049177193
-
The pattern-recognition molecule Nod1 is localized at the plasma membrane at sites of bacterial interaction
-
Kufer TA, Kremmer E, Adam AC, Philpott DJ, Sansonetti PJ. The pattern-recognition molecule Nod1 is localized at the plasma membrane at sites of bacterial interaction. Cell Microbiol 2008 10 : 477 486.
-
(2008)
Cell Microbiol
, vol.10
, pp. 477-486
-
-
Kufer, T.A.1
Kremmer, E.2
Adam, A.C.3
Philpott, D.J.4
Sansonetti, P.J.5
-
31
-
-
22244465576
-
Membrane recruitment of NOD2 in intestinal epithelial cells is essential for nuclear factor-{kappa}B activation in muramyl dipeptide recognition
-
Barnich N, Aguirre JE, Reinecker HC, Xavier R, Podolsky DK. Membrane recruitment of NOD2 in intestinal epithelial cells is essential for nuclear factor-{kappa}B activation in muramyl dipeptide recognition. J Cell Biol 2005 170 : 21 26.
-
(2005)
J Cell Biol
, vol.170
, pp. 21-26
-
-
Barnich, N.1
Aguirre, J.E.2
Reinecker, H.C.3
Xavier, R.4
Podolsky, D.K.5
-
32
-
-
45549093755
-
A NOD2-NALP1 complex mediates caspase-1-dependent IL-1beta secretion in response to Bacillus anthracis infection and muramyl dipeptide
-
Hsu LC, et al. A NOD2-NALP1 complex mediates caspase-1-dependent IL-1beta secretion in response to Bacillus anthracis infection and muramyl dipeptide. Proc Natl Acad Sci USA 2008 105 : 7803 7808.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 7803-7808
-
-
Hsu, L.C.1
-
33
-
-
33751423867
-
Solution structure of NOD1 CARD and mutational analysis of its interaction with the CARD of downstream kinase RICK
-
Manon F, Favier A, Nunez G, Simorre JP, Cusack S. Solution structure of NOD1 CARD and mutational analysis of its interaction with the CARD of downstream kinase RICK. J Mol Biol 2007 365 : 160 174.
-
(2007)
J Mol Biol
, vol.365
, pp. 160-174
-
-
Manon, F.1
Favier, A.2
Nunez, G.3
Simorre, J.P.4
Cusack, S.5
-
34
-
-
33845679055
-
Crystal structure of the Nod1 caspase activation and recruitment domain
-
Coussens NP, Mowers JC, McDonald C, Nunez G, Ramaswamy S. Crystal structure of the Nod1 caspase activation and recruitment domain. Biochem Biophys Res Commun 2007 353 : 1 5.
-
(2007)
Biochem Biophys Res Commun
, vol.353
, pp. 1-5
-
-
Coussens, N.P.1
Mowers, J.C.2
McDonald, C.3
Nunez, G.4
Ramaswamy, S.5
-
35
-
-
4444376712
-
Signaling to NF-kappaB
-
Hayden MS, Ghosh S. Signaling to NF-kappaB. Genes Dev 2004 18 : 2195 2224.
-
(2004)
Genes Dev
, vol.18
, pp. 2195-2224
-
-
Hayden, M.S.1
Ghosh, S.2
-
36
-
-
20144382924
-
Peptidoglycan signaling in innate immunity and inflammatory disease
-
McDonald C, Inohara N, Nunez G. Peptidoglycan signaling in innate immunity and inflammatory disease. J Biol Chem 2005 280 : 20177 20180.
-
(2005)
J Biol Chem
, vol.280
, pp. 20177-20180
-
-
McDonald, C.1
Inohara, N.2
Nunez, G.3
-
37
-
-
0038615855
-
Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan
-
Girardin SE, et al. Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan. Science 2003 300 : 1584 1587.
-
(2003)
Science
, vol.300
, pp. 1584-1587
-
-
Girardin, S.E.1
-
38
-
-
0038824980
-
An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid
-
Chamaillard M, et al. An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid. Nat Immunol 2003 4 : 702 707.
-
(2003)
Nat Immunol
, vol.4
, pp. 702-707
-
-
Chamaillard, M.1
-
39
-
-
0142180157
-
Peptidoglycan molecular requirements allowing detection by Nod1 and Nod2
-
Girardin SE, et al. Peptidoglycan molecular requirements allowing detection by Nod1 and Nod2. J Biol Chem 2003 278 : 41702 41708.
-
(2003)
J Biol Chem
, vol.278
, pp. 41702-41708
-
-
Girardin, S.E.1
-
40
-
-
0037075551
-
RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems
-
Kobayashi K, et al. RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems. Nature 2002 416 : 194 199.
-
(2002)
Nature
, vol.416
, pp. 194-199
-
-
Kobayashi, K.1
-
41
-
-
13244292161
-
Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract
-
Kobayashi KS, et al. Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract. Science 2005 307 : 731 734.
-
(2005)
Science
, vol.307
, pp. 731-734
-
-
Kobayashi, K.S.1
-
42
-
-
33846936219
-
RICK/RIP2 mediates innate immune responses induced through Nod1 and Nod2 but not TLRs
-
Park JH, et al. RICK/RIP2 mediates innate immune responses induced through Nod1 and Nod2 but not TLRs. J Immunol 2007 178 : 2380 2386.
-
(2007)
J Immunol
, vol.178
, pp. 2380-2386
-
-
Park, J.H.1
-
43
-
-
34250888664
-
Nod1/RICK and TLR signaling regulate chemokine and antimicrobial innate immune responses in mesothelial cells
-
Park JH, et al. Nod1/RICK and TLR signaling regulate chemokine and antimicrobial innate immune responses in mesothelial cells. J Immunol 2007 179 : 514 521.
-
(2007)
J Immunol
, vol.179
, pp. 514-521
-
-
Park, J.H.1
-
44
-
-
56149111709
-
Cross-tolerization between Nod1 and Nod2 signaling results in reduced refractoriness to bacterial infection in Nod2-deficient macrophages
-
Kim YG, Park JH, Daignault S, Fukase K, Nunez G. Cross-tolerization between Nod1 and Nod2 signaling results in reduced refractoriness to bacterial infection in Nod2-deficient macrophages. J Immunol 2008 181 : 4340 4346.
-
(2008)
J Immunol
, vol.181
, pp. 4340-4346
-
-
Kim, Y.G.1
Park, J.H.2
Daignault, S.3
Fukase, K.4
Nunez, G.5
-
45
-
-
39149094587
-
The cytosolic sensors Nod1 and Nod2 are critical for bacterial recognition and host defense after exposure to Toll-like receptor ligands
-
Kim YG, Park JH, Shaw MH, Franchi L, Inohara N, Nunez G. The cytosolic sensors Nod1 and Nod2 are critical for bacterial recognition and host defense after exposure to Toll-like receptor ligands. Immunity 2008 28 : 246 257.
-
(2008)
Immunity
, vol.28
, pp. 246-257
-
-
Kim, Y.G.1
Park, J.H.2
Shaw, M.H.3
Franchi, L.4
Inohara, N.5
Nunez, G.6
-
46
-
-
0034623225
-
An induced proximity model for NF-kappa B activation in the Nod1/RICK and RIP signaling pathways
-
Inohara N, et al. An induced proximity model for NF-kappa B activation in the Nod1/RICK and RIP signaling pathways. J Biol Chem 2000 275 : 27823 27831.
-
(2000)
J Biol Chem
, vol.275
, pp. 27823-27831
-
-
Inohara, N.1
-
47
-
-
38549084725
-
A critical role of RICK/ RIP2 polyubiquitination in Nod-induced NF-kappaB activation
-
Hasegawa M, et al. A critical role of RICK/ RIP2 polyubiquitination in Nod-induced NF-kappaB activation. EMBO J 2008 27 : 373 383.
-
(2008)
EMBO J
, vol.27
, pp. 373-383
-
-
Hasegawa, M.1
-
48
-
-
11144289688
-
The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO
-
Abbott DW, Wilkins A, Asara JM, Cantley LC. The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO. Curr Biol 2004 14 : 2217 2227.
-
(2004)
Curr Biol
, vol.14
, pp. 2217-2227
-
-
Abbott, D.W.1
Wilkins, A.2
Asara, J.M.3
Cantley, L.C.4
-
49
-
-
38049153165
-
TAK1 is a central mediator of NOD2 signaling in epidermal cells
-
Kim JY, Omori E, Matsumoto K, Nunez G, Ninomiya-Tsuji J. TAK1 is a central mediator of NOD2 signaling in epidermal cells. J Biol Chem 2008 283 : 137 144.
-
(2008)
J Biol Chem
, vol.283
, pp. 137-144
-
-
Kim, J.Y.1
Omori, E.2
Matsumoto, K.3
Nunez, G.4
Ninomiya-Tsuji, J.5
-
50
-
-
0346243941
-
Role of the TAB2-related protein TAB3 in IL-1 and TNF signaling
-
Ishitani T, Takaesu G, Ninomiya-Tsuji J, Shibuya H, Gaynor RB, Matsumoto K. Role of the TAB2-related protein TAB3 in IL-1 and TNF signaling. EMBO J 2003 22 : 6277 6288.
-
(2003)
EMBO J
, vol.22
, pp. 6277-6288
-
-
Ishitani, T.1
Takaesu, G.2
Ninomiya-Tsuji, J.3
Shibuya, H.4
Gaynor, R.B.5
Matsumoto, K.6
-
51
-
-
27744577296
-
TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo
-
Shim JH, et al. TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo. Genes Dev 2005 19 : 2668 2681.
-
(2005)
Genes Dev
, vol.19
, pp. 2668-2681
-
-
Shim, J.H.1
-
52
-
-
27544434183
-
Essential function for the kinase TAK1 in innate and adaptive immune responses
-
Sato S, et al. Essential function for the kinase TAK1 in innate and adaptive immune responses. Nat Immunol 2005 6 : 1087 1095.
-
(2005)
Nat Immunol
, vol.6
, pp. 1087-1095
-
-
Sato, S.1
-
53
-
-
34249826059
-
Molecular mechanisms involved in the regulation of cytokine production by muramyl dipeptide
-
Windheim M, Lang C, Peggie M, Plater LA, Cohen P. Molecular mechanisms involved in the regulation of cytokine production by muramyl dipeptide. Biochem J 2007 404 : 179 190.
-
(2007)
Biochem J
, vol.404
, pp. 179-190
-
-
Windheim, M.1
Lang, C.2
Peggie, M.3
Plater, L.A.4
Cohen, P.5
-
54
-
-
33947379719
-
Regulation of Nod1-mediated signaling pathways
-
da Silva Correia J, Miranda Y, Leonard N, Hsu J, Ulevitch RJ. Regulation of Nod1-mediated signaling pathways. Cell Death Differ 2007 14 : 830 839.
-
(2007)
Cell Death Differ
, vol.14
, pp. 830-839
-
-
Da Silva Correia, J.1
Miranda, Y.2
Leonard, N.3
Hsu, J.4
Ulevitch, R.J.5
-
55
-
-
33646382812
-
Stimulation of the cytosolic receptor for peptidoglycan, Nod1, by infection with Chlamydia trachomatis or Chlamydia muridarum
-
Welter-Stahl L, et al. Stimulation of the cytosolic receptor for peptidoglycan, Nod1, by infection with Chlamydia trachomatis or Chlamydia muridarum. Cell Microbiol 2006 8 : 1047 1057.
-
(2006)
Cell Microbiol
, vol.8
, pp. 1047-1057
-
-
Welter-Stahl, L.1
-
56
-
-
1342344961
-
Nod1 is an essential signal transducer in intestinal epithelial cells infected with bacteria that avoid recognition by toll-like receptors
-
Kim JG, Lee SJ, Kagnoff MF. Nod1 is an essential signal transducer in intestinal epithelial cells infected with bacteria that avoid recognition by toll-like receptors. Infect Immun 2004 72 : 1487 1495.
-
(2004)
Infect Immun
, vol.72
, pp. 1487-1495
-
-
Kim, J.G.1
Lee, S.J.2
Kagnoff, M.F.3
-
57
-
-
27744606975
-
Nod1 participates in the innate immune response to Pseudomonas aeruginosa
-
Travassos LH, et al. Nod1 participates in the innate immune response to Pseudomonas aeruginosa. J Biol Chem 2005 280 : 36714 36718.
-
(2005)
J Biol Chem
, vol.280
, pp. 36714-36718
-
-
Travassos, L.H.1
-
58
-
-
46449093146
-
The cytosolic pattern recognition receptor NOD1 induces inflammatory interleukin-8 during Chlamydia trachomatis infection
-
Buchholz KR, Stephens RS. The cytosolic pattern recognition receptor NOD1 induces inflammatory interleukin-8 during Chlamydia trachomatis infection. Infect Immun 2008 76 : 3150 3155.
-
(2008)
Infect Immun
, vol.76
, pp. 3150-3155
-
-
Buchholz, K.R.1
Stephens, R.S.2
-
59
-
-
34548799291
-
Nod1 and Nod2 induce CCL5/RANTES through the NF-kappaB pathway
-
Werts C, et al. Nod1 and Nod2 induce CCL5/RANTES through the NF-kappaB pathway. Eur J Immunol 2007 37 : 2499 2508.
-
(2007)
Eur J Immunol
, vol.37
, pp. 2499-2508
-
-
Werts, C.1
-
60
-
-
31944437924
-
Nod1 acts as an intracellular receptor to stimulate chemokine production and neutrophil recruitment in vivo
-
Masumoto J, et al. Nod1 acts as an intracellular receptor to stimulate chemokine production and neutrophil recruitment in vivo. J Exp Med 2006 203 : 203 213.
-
(2006)
J Exp Med
, vol.203
, pp. 203-213
-
-
Masumoto, J.1
-
61
-
-
33744965671
-
Nucleotide-binding oligomerization domain-1 and epidermal growth factor receptor: Critical regulators of beta-defensins during Helicobacter pylori infection
-
Boughan PK, et al. Nucleotide-binding oligomerization domain-1 and epidermal growth factor receptor: critical regulators of beta-defensins during Helicobacter pylori infection. J Biol Chem 2006 281 : 11637 11648.
-
(2006)
J Biol Chem
, vol.281
, pp. 11637-11648
-
-
Boughan, P.K.1
-
62
-
-
34548425221
-
A major role for intestinal epithelial nucleotide oligomerization domain 1 (NOD1) in eliciting host bactericidal immune responses to Campylobacter jejuni
-
Zilbauer M, et al. A major role for intestinal epithelial nucleotide oligomerization domain 1 (NOD1) in eliciting host bactericidal immune responses to Campylobacter jejuni. Cell Microbiol 2007 9 : 2404 2416.
-
(2007)
Cell Microbiol
, vol.9
, pp. 2404-2416
-
-
Zilbauer, M.1
-
63
-
-
33644772156
-
A short isoform of NOD2/CARD15, NOD2-S, is an endogenous inhibitor of NOD2/receptor-interacting protein kinase 2-induced signaling pathways
-
Rosenstiel P, et al. A short isoform of NOD2/CARD15, NOD2-S, is an endogenous inhibitor of NOD2/receptor-interacting protein kinase 2-induced signaling pathways. Proc Natl Acad Sci USA 2006 103 : 3280 3285.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 3280-3285
-
-
Rosenstiel, P.1
-
64
-
-
40149084641
-
Caspase-12 modulates NOD signaling and regulates antimicrobial peptide production and mucosal immunity
-
Leblanc PM, et al. Caspase-12 modulates NOD signaling and regulates antimicrobial peptide production and mucosal immunity. Cell Host Microbe 2008 3 : 146 157.
-
(2008)
Cell Host Microbe
, vol.3
, pp. 146-157
-
-
Leblanc, P.M.1
-
65
-
-
52049114650
-
MEKK4 sequesters RIP2 to dictate NOD2 signal specificity
-
Clark NM, Marinis JM, Cobb BA, Abbott DW. MEKK4 sequesters RIP2 to dictate NOD2 signal specificity. Curr Biol 2008 18 : 1402 1408.
-
(2008)
Curr Biol
, vol.18
, pp. 1402-1408
-
-
Clark, N.M.1
Marinis, J.M.2
Cobb, B.A.3
Abbott, D.W.4
-
67
-
-
28844448136
-
A role for Erbin in the regulation of Nod2-dependent NF-kappaB signaling
-
McDonald C, et al. A role for Erbin in the regulation of Nod2-dependent NF-kappaB signaling. J Biol Chem 2005 280 : 40301 40309.
-
(2005)
J Biol Chem
, vol.280
, pp. 40301-40309
-
-
McDonald, C.1
-
68
-
-
40449136493
-
The ubiquitin-editing enzyme A20 restricts nucleotide-binding oligomerization domain containing 2-triggered signals
-
Hitotsumatsu O, et al. The ubiquitin-editing enzyme A20 restricts nucleotide-binding oligomerization domain containing 2-triggered signals. Immunity 2008 28 : 381 390.
-
(2008)
Immunity
, vol.28
, pp. 381-390
-
-
Hitotsumatsu, O.1
-
69
-
-
0034730713
-
Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice
-
Lee EG, et al. Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice. Science 2000 289 : 2350 2354.
-
(2000)
Science
, vol.289
, pp. 2350-2354
-
-
Lee, E.G.1
-
70
-
-
5444223519
-
The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses
-
Boone DL, et al. The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses. Nat Immunol 2004 5 : 1052 1060.
-
(2004)
Nat Immunol
, vol.5
, pp. 1052-1060
-
-
Boone, D.L.1
-
71
-
-
3943054838
-
De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling
-
Wertz IE, et al. De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling. Nature 2004 430 : 694 699.
-
(2004)
Nature
, vol.430
, pp. 694-699
-
-
Wertz, I.E.1
-
72
-
-
14044268789
-
Nod1-mediated endothelial cell activation by Chlamydophila pneumoniae
-
Opitz B, et al. Nod1-mediated endothelial cell activation by Chlamydophila pneumoniae. Circ Res 2005 96 : 319 326.
-
(2005)
Circ Res
, vol.96
, pp. 319-326
-
-
Opitz, B.1
-
73
-
-
33846526208
-
A critical role for peptidoglycan N-deacetylation in Listeria evasion from the host innate immune system
-
Boneca IG, et al. A critical role for peptidoglycan N-deacetylation in Listeria evasion from the host innate immune system. Proc Natl Acad Sci USA 2007 104 : 997 1002.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 997-1002
-
-
Boneca, I.G.1
-
74
-
-
33749384363
-
Differential release and distribution of Nod1 and Nod2 immunostimulatory molecules among bacterial species and environments
-
Hasegawa M, et al. Differential release and distribution of Nod1 and Nod2 immunostimulatory molecules among bacterial species and environments. J Biol Chem 2006 281 : 29054 29063.
-
(2006)
J Biol Chem
, vol.281
, pp. 29054-29063
-
-
Hasegawa, M.1
-
75
-
-
0037858060
-
Growth of the stress-bearing and shape-maintaining murein sacculus of Escherichia coli
-
Holtje JV. Growth of the stress-bearing and shape-maintaining murein sacculus of Escherichia coli. Microbiol Mol Biol Rev 1998 62 : 181 203.
-
(1998)
Microbiol Mol Biol Rev
, vol.62
, pp. 181-203
-
-
Holtje, J.V.1
-
76
-
-
0021881891
-
Recycling of murein by Escherichia coli
-
Goodell EW. Recycling of murein by Escherichia coli. J Bacteriol 1985 163 : 305 310.
-
(1985)
J Bacteriol
, vol.163
, pp. 305-310
-
-
Goodell, E.W.1
-
77
-
-
38849087905
-
Muramylpeptide shedding modulates cell sensing of Shigella flexneri
-
Nigro G, et al. Muramylpeptide shedding modulates cell sensing of Shigella flexneri. Cell Microbiol 2008 10 : 682 695.
-
(2008)
Cell Microbiol
, vol.10
, pp. 682-695
-
-
Nigro, G.1
-
78
-
-
17944380130
-
CARD4/Nod1 mediates NF-kappaB and JNK activation by invasive Shigella flexneri
-
Girardin SE, et al. CARD4/Nod1 mediates NF-kappaB and JNK activation by invasive Shigella flexneri. EMBO Rep 2001 2 : 736 742.
-
(2001)
EMBO Rep
, vol.2
, pp. 736-742
-
-
Girardin, S.E.1
-
79
-
-
9244245293
-
Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island
-
Viala J, et al. Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island. Nat Immunol 2004 5 : 1166 1174.
-
(2004)
Nat Immunol
, vol.5
, pp. 1166-1174
-
-
Viala, J.1
-
80
-
-
34047256589
-
Nod1 mediates cytoplasmic sensing of combinations of extracellular bacteria
-
Ratner AJ, Aguilar JL, Shchepetov M, Lysenko ES, Weiser JN. Nod1 mediates cytoplasmic sensing of combinations of extracellular bacteria. Cell Microbiol 2007 9 : 1343 1351.
-
(2007)
Cell Microbiol
, vol.9
, pp. 1343-1351
-
-
Ratner, A.J.1
Aguilar, J.L.2
Shchepetov, M.3
Lysenko, E.S.4
Weiser, J.N.5
-
81
-
-
44849136632
-
Pannexin-1-mediated intracellular delivery of muramyl dipeptide induces caspase-1 activation via Cryopyrin/NLRP3 independently of Nod2
-
Marina-Garcia N, et al. Pannexin-1-mediated intracellular delivery of muramyl dipeptide induces caspase-1 activation via Cryopyrin/NLRP3 independently of Nod2. J Immunol 2008 180 : 4050 4057.
-
(2008)
J Immunol
, vol.180
, pp. 4050-4057
-
-
Marina-Garcia, N.1
-
82
-
-
34248152308
-
HPepT1 selectively transports muramyl dipeptide but not Nod1-activating muramyl peptides
-
Ismair MG, Vavricka SR, Kullak-Ublick GA, Fried M, Mengin-Lecreulx D, Girardin SE. hPepT1 selectively transports muramyl dipeptide but not Nod1-activating muramyl peptides. Can J Physiol Pharmacol 2006 84 : 1313 1319.
-
(2006)
Can J Physiol Pharmacol
, vol.84
, pp. 1313-1319
-
-
Ismair, M.G.1
Vavricka, S.R.2
Kullak-Ublick, G.A.3
Fried, M.4
Mengin-Lecreulx, D.5
Girardin, S.E.6
-
83
-
-
51849094527
-
Bacterial peptide recognition and immune activation facilitated by human peptide transporter PEPT2
-
Swaan PW, et al. Bacterial peptide recognition and immune activation facilitated by human peptide transporter PEPT2. Am J Respir Cell Mol Biol 2008 39 : 536 542.
-
(2008)
Am J Respir Cell Mol Biol
, vol.39
, pp. 536-542
-
-
Swaan, P.W.1
-
84
-
-
33745807413
-
The renal type H+/peptide symporter PEPT2: Structure-affinity relationships
-
Biegel A, et al. The renal type H+/peptide symporter PEPT2: structure-affinity relationships. Amino Acids 2006 31 : 137 156.
-
(2006)
Amino Acids
, vol.31
, pp. 137-156
-
-
Biegel, A.1
-
85
-
-
4344699028
-
Nucleotide-binding oligomerization domain proteins are innate immune receptors for internalized Streptococcus pneumoniae
-
Opitz B, et al. Nucleotide-binding oligomerization domain proteins are innate immune receptors for internalized Streptococcus pneumoniae. J Biol Chem 2004 279 : 36426 36432.
-
(2004)
J Biol Chem
, vol.279
, pp. 36426-36432
-
-
Opitz, B.1
-
86
-
-
77951073629
-
NOD2 and toll-like receptors are nonredundant recognition systems of Mycobacterium tuberculosis
-
Ferwerda G, et al. NOD2 and toll-like receptors are nonredundant recognition systems of Mycobacterium tuberculosis. PLoS Pathog 2005 1 : 279 285.
-
(2005)
PLoS Pathog
, vol.1
, pp. 279-285
-
-
Ferwerda, G.1
-
87
-
-
0012722659
-
Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection
-
Girardin SE, et al. Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection. J Biol Chem 2003 278 : 8869 8872.
-
(2003)
J Biol Chem
, vol.278
, pp. 8869-8872
-
-
Girardin, S.E.1
-
88
-
-
50949098448
-
Nod2 mediates susceptibility to Yersinia pseudotuberculosis in mice
-
Meinzer U, et al. Nod2 mediates susceptibility to Yersinia pseudotuberculosis in mice. PLoS ONE 2008 3 : e2769.
-
(2008)
PLoS ONE
, vol.3
-
-
Meinzer, U.1
-
89
-
-
23844521000
-
Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists
-
Fritz JH, et al. Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists. Eur J Immunol 2005 35 : 2459 2470.
-
(2005)
Eur J Immunol
, vol.35
, pp. 2459-2470
-
-
Fritz, J.H.1
-
90
-
-
38949091132
-
Distinct TLR- and NLR-mediated transcriptional responses to an intracellular pathogen
-
Leber JH, Crimmins GT, Raghavan S, Meyer-Morse NP, Cox JS, Portnoy DA. Distinct TLR- and NLR-mediated transcriptional responses to an intracellular pathogen. PLoS Pathog 2008 4 : e6.
-
(2008)
PLoS Pathog
, vol.4
-
-
Leber, J.H.1
Crimmins, G.T.2
Raghavan, S.3
Meyer-Morse, N.P.4
Cox, J.S.5
Portnoy, D.A.6
-
91
-
-
0025970427
-
Endotoxemia in human septic shock
-
Danner RL, Elin RJ, Hosseini JM, Wesley RA, Reilly JM, Parillo JE. Endotoxemia in human septic shock. Chest 1991 99 : 169 175.
-
(1991)
Chest
, vol.99
, pp. 169-175
-
-
Danner, R.L.1
Elin, R.J.2
Hosseini, J.M.3
Wesley, R.A.4
Reilly, J.M.5
Parillo, J.E.6
-
92
-
-
5444254408
-
Toll-like receptors in the pathogenesis of human disease
-
Cook DN, Pisetsky DS, Schwartz DA. Toll-like receptors in the pathogenesis of human disease. Nat Immunol 2004 5 : 975 979.
-
(2004)
Nat Immunol
, vol.5
, pp. 975-979
-
-
Cook, D.N.1
Pisetsky, D.S.2
Schwartz, D.A.3
-
93
-
-
0030917203
-
Monocyte deactivation in septic patients: Restoration by IFN-gamma treatment
-
Docke WD, et al. Monocyte deactivation in septic patients: restoration by IFN-gamma treatment. Nat Med 1997 3 : 678 681.
-
(1997)
Nat Med
, vol.3
, pp. 678-681
-
-
Docke, W.D.1
-
94
-
-
0023176617
-
Neutrophil recruitment and bacterial clearance correlated with LPS responsiveness in local gram-negative infection
-
Shahin RD, Engberg I, Hagberg L, Svanborg Eden C. Neutrophil recruitment and bacterial clearance correlated with LPS responsiveness in local gram-negative infection. J Immunol 1987 138 : 3475 3480.
-
(1987)
J Immunol
, vol.138
, pp. 3475-3480
-
-
Shahin, R.D.1
Engberg, I.2
Hagberg, L.3
Svanborg Eden, C.4
-
95
-
-
20644450804
-
Negative regulation of toll-like receptor-mediated immune responses
-
Liew FY, Xu D, Brint EK, O'Neill LA. Negative regulation of toll-like receptor-mediated immune responses. Nat Rev Immunol 2005 5 : 446 458.
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 446-458
-
-
Liew, F.Y.1
Xu, D.2
Brint, E.K.3
O'Neill, L.A.4
-
96
-
-
39549120903
-
Crohn's disease patients homozygous for the 3020insC NOD2 mutation have a defective NOD2/TLR4 cross-tolerance to intestinal stimuli
-
Kullberg BJ, et al. Crohn's disease patients homozygous for the 3020insC NOD2 mutation have a defective NOD2/TLR4 cross-tolerance to intestinal stimuli. Immunology 2008 123 : 600 605.
-
(2008)
Immunology
, vol.123
, pp. 600-605
-
-
Kullberg, B.J.1
-
97
-
-
37649013801
-
Chronic stimulation of Nod2 mediates tolerance to bacterial products
-
Hedl M, Li J, Cho JH, Abraham C. Chronic stimulation of Nod2 mediates tolerance to bacterial products. Proc Natl Acad Sci USA 2007 104 : 19440 19445.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 19440-19445
-
-
Hedl, M.1
Li, J.2
Cho, J.H.3
Abraham, C.4
-
98
-
-
0000675671
-
Muramyl dipeptide and derivatives
-
In: Stewart-Tull, D.E.S., ed. New York: Wiley & Sons
-
Takada H, Kotani S. Muramyl dipeptide and derivatives. In : Stewart-Tull DES, ed. The Theory of Practical Application of Adjuvants. New York : Wiley & Sons, 1995 : 171 202.
-
(1995)
The Theory of Practical Application of Adjuvants.
, pp. 171-202
-
-
Takada, H.1
Kotani, S.2
-
99
-
-
0037458665
-
Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease
-
Inohara N, et al. Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease. J Biol Chem 2003 278 : 5509 5512.
-
(2003)
J Biol Chem
, vol.278
, pp. 5509-5512
-
-
Inohara, N.1
-
100
-
-
0037022296
-
Human macrophage activation programs induced by bacterial pathogens
-
Nau GJ, Richmond JF, Schlesinger A, Jennings EG, Lander ES, Young RA. Human macrophage activation programs induced by bacterial pathogens. Proc Natl Acad Sci USA 2002 99 : 1503 1508.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 1503-1508
-
-
Nau, G.J.1
Richmond, J.F.2
Schlesinger, A.3
Jennings, E.G.4
Lander, E.S.5
Young, R.A.6
-
101
-
-
0035213770
-
Muramyl dipeptide-Lys stimulates the function of human dendritic cells
-
Todate A, Suda T, Kuwata H, Chida K, Nakamura H. Muramyl dipeptide-Lys stimulates the function of human dendritic cells. J Leukoc Biol 2001 70 : 723 729.
-
(2001)
J Leukoc Biol
, vol.70
, pp. 723-729
-
-
Todate, A.1
Suda, T.2
Kuwata, H.3
Chida, K.4
Nakamura, H.5
-
102
-
-
0034691601
-
Endotoxin and muramyl dipeptide modulate surface receptor expression on human mononuclear cells
-
Heinzelmann M, Polk HC Jr., Chernobelsky A, Stites TP, Gordon LE. Endotoxin and muramyl dipeptide modulate surface receptor expression on human mononuclear cells. Immunopharmacology 2000 48 : 117 128.
-
(2000)
Immunopharmacology
, vol.48
, pp. 117-128
-
-
Heinzelmann, M.1
Polk Jr., H.C.2
Chernobelsky, A.3
Stites, T.P.4
Gordon, L.E.5
-
103
-
-
35348948374
-
Stimulation of the intracellular bacterial sensor NOD2 programs dendritic cells to promote interleukin-17 production in human memory T cells
-
van Beelen AJ, et al. Stimulation of the intracellular bacterial sensor NOD2 programs dendritic cells to promote interleukin-17 production in human memory T cells. Immunity 2007 27 : 660 669.
-
(2007)
Immunity
, vol.27
, pp. 660-669
-
-
Van Beelen, A.J.1
-
104
-
-
34247254780
-
Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity
-
Fritz JH, et al. Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity. Immunity 2007 26 : 445 459.
-
(2007)
Immunity
, vol.26
, pp. 445-459
-
-
Fritz, J.H.1
-
105
-
-
0035978533
-
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
-
Ogura Y, et al. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 2001 411 : 603 606.
-
(2001)
Nature
, vol.411
, pp. 603-606
-
-
Ogura, Y.1
-
106
-
-
0035978651
-
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
-
Hugot JP, et al. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 2001 411 : 599 603.
-
(2001)
Nature
, vol.411
, pp. 599-603
-
-
Hugot, J.P.1
-
107
-
-
11144279151
-
Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: A metaanalysis
-
Economou M, Trikalinos TA, Loizou KT, Tsianos EV, Ioannidis JP. Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: a metaanalysis. Am J Gastroenterol 2004 99 : 2393 2404.
-
(2004)
Am J Gastroenterol
, vol.99
, pp. 2393-2404
-
-
Economou, M.1
Trikalinos, T.A.2
Loizou, K.T.3
Tsianos, E.V.4
Ioannidis, J.P.5
-
108
-
-
0037379679
-
Genetic variation and activity of mouse Nod2, a susceptibility gene for Crohn's disease
-
Ogura Y, Saab L, Chen FF, Benito A, Inohara N, Nunez G. Genetic variation and activity of mouse Nod2, a susceptibility gene for Crohn's disease. Genomics 2003 81 : 369 377.
-
(2003)
Genomics
, vol.81
, pp. 369-377
-
-
Ogura, Y.1
Saab, L.2
Chen, F.F.3
Benito, A.4
Inohara, N.5
Nunez, G.6
-
109
-
-
21144468350
-
Muramyl dipeptide and toll-like receptor sensitivity in NOD2-associated Crohn's disease
-
van Heel DA, et al. Muramyl dipeptide and toll-like receptor sensitivity in NOD2-associated Crohn's disease. Lancet 2005 365 : 1794 1796.
-
(2005)
Lancet
, vol.365
, pp. 1794-1796
-
-
Van Heel, D.A.1
-
110
-
-
4444332518
-
Regulation of IL-8 and IL-1beta expression in Crohn's disease associated NOD2/CARD15 mutations
-
Li J, et al. Regulation of IL-8 and IL-1beta expression in Crohn's disease associated NOD2/CARD15 mutations. Hum Mol Genet 2004 13 : 1715 1725.
-
(2004)
Hum Mol Genet
, vol.13
, pp. 1715-1725
-
-
Li, J.1
-
111
-
-
7244257312
-
NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal alpha-defensin expression
-
Wehkamp J, et al. NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal alpha-defensin expression. Gut 2004 53 : 1658 1664.
-
(2004)
Gut
, vol.53
, pp. 1658-1664
-
-
Wehkamp, J.1
-
112
-
-
26044460479
-
NOD2 3020insC mutation and the pathogenesis of Crohn's disease: Impaired IL-1beta production points to a loss-of-function phenotype
-
Netea MG, Ferwerda G, de Jong DJ, Girardin SE, Kullberg BJ, van der Meer JW. NOD2 3020insC mutation and the pathogenesis of Crohn's disease: impaired IL-1beta production points to a loss-of-function phenotype. Neth J Med 2005 63 : 305 308.
-
(2005)
Neth J Med
, vol.63
, pp. 305-308
-
-
Netea, M.G.1
Ferwerda, G.2
De Jong, D.J.3
Girardin, S.E.4
Kullberg, B.J.5
Van Der Meer, J.W.6
-
113
-
-
0038109983
-
Crohn's disease and the NOD2 gene: A role for paneth cells
-
Lala S, et al. Crohn's disease and the NOD2 gene: a role for paneth cells. Gastroenterology 2003 125 : 47 57.
-
(2003)
Gastroenterology
, vol.125
, pp. 47-57
-
-
Lala, S.1
-
114
-
-
46349102893
-
Reduced alpha-defensin expression is associated with inflammation and not NOD2 mutation status in ileal Crohn's disease
-
Simms LA, Doecke JD, Walsh MD, Huang N, Fowler EV, Radford-Smith GL. Reduced alpha-defensin expression is associated with inflammation and not NOD2 mutation status in ileal Crohn's disease. Gut 2008 57 : 903 910.
-
(2008)
Gut
, vol.57
, pp. 903-910
-
-
Simms, L.A.1
Doecke, J.D.2
Walsh, M.D.3
Huang, N.4
Fowler, E.V.5
Radford-Smith, G.L.6
-
115
-
-
1842588607
-
Toll-like receptor 2 is required for optimal control of Listeria monocytogenes infection
-
Torres D, et al. Toll-like receptor 2 is required for optimal control of Listeria monocytogenes infection. Infect Immun 2004 72 : 2131 2139.
-
(2004)
Infect Immun
, vol.72
, pp. 2131-2139
-
-
Torres, D.1
-
116
-
-
2442550786
-
Toll-like receptor 4 dependence of innate and adaptive immunity to Salmonella: Importance of the Kupffer cell network
-
Vazquez-Torres A, et al. Toll-like receptor 4 dependence of innate and adaptive immunity to Salmonella: importance of the Kupffer cell network. J Immunol 2004 172 : 6202 6208.
-
(2004)
J Immunol
, vol.172
, pp. 6202-6208
-
-
Vazquez-Torres, A.1
-
117
-
-
34047173496
-
Epithelial NEMO links innate immunity to chronic intestinal inflammation
-
Nenci A, et al. Epithelial NEMO links innate immunity to chronic intestinal inflammation. Nature 2007 446 : 557 561.
-
(2007)
Nature
, vol.446
, pp. 557-561
-
-
Nenci, A.1
-
118
-
-
4444253690
-
NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses
-
Watanabe T, Kitani A, Murray PJ, Strober W. NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses. Nat Immunol 2004 5 : 800 808.
-
(2004)
Nat Immunol
, vol.5
, pp. 800-808
-
-
Watanabe, T.1
Kitani, A.2
Murray, P.J.3
Strober, W.4
-
119
-
-
38849163741
-
Muramyl dipeptide activation of nucleotide-binding oligomerization domain 2 protects mice from experimental colitis
-
Watanabe T, et al. Muramyl dipeptide activation of nucleotide-binding oligomerization domain 2 protects mice from experimental colitis. J Clin Invest 2008 118 : 545 559.
-
(2008)
J Clin Invest
, vol.118
, pp. 545-559
-
-
Watanabe, T.1
-
120
-
-
33748493563
-
Nucleotide binding oligomerization domain 2 deficiency leads to dysregulated TLR2 signaling and induction of antigen-specific colitis
-
Watanabe T, Kitani A, Murray PJ, Wakatsuki Y, Fuss IJ, Strober W. Nucleotide binding oligomerization domain 2 deficiency leads to dysregulated TLR2 signaling and induction of antigen-specific colitis. Immunity 2006 25 : 473 485.
-
(2006)
Immunity
, vol.25
, pp. 473-485
-
-
Watanabe, T.1
Kitani, A.2
Murray, P.J.3
Wakatsuki, Y.4
Fuss, I.J.5
Strober, W.6
-
121
-
-
49849096752
-
NOD2/CARD15 genotype influences MDP-induced cytokine release and basal IL-12p40 levels in primary isolated peripheral blood monocytes
-
Beynon V, et al. NOD2/CARD15 genotype influences MDP-induced cytokine release and basal IL-12p40 levels in primary isolated peripheral blood monocytes. Inflamm Bowel Dis 2008 14 : 1033 1040.
-
(2008)
Inflamm Bowel Dis
, vol.14
, pp. 1033-1040
-
-
Beynon, V.1
-
122
-
-
46049111062
-
Monocyte-derived dendritic cells from Crohn patients show differential NOD2/CARD15-dependent immune responses to bacteria
-
Salucci V, et al. Monocyte-derived dendritic cells from Crohn patients show differential NOD2/CARD15-dependent immune responses to bacteria. Inflamm Bowel Dis 2008 14 : 812 818.
-
(2008)
Inflamm Bowel Dis
, vol.14
, pp. 812-818
-
-
Salucci, V.1
-
123
-
-
33745556685
-
Impaired dendritic cell function in Crohn's disease patients with NOD2 3020insC mutation
-
Kramer M, Netea MG, de Jong DJ, Kullberg BJ, Adema GJ. Impaired dendritic cell function in Crohn's disease patients with NOD2 3020insC mutation. J Leukoc Biol 2006 79 : 860 866.
-
(2006)
J Leukoc Biol
, vol.79
, pp. 860-866
-
-
Kramer, M.1
Netea, M.G.2
De Jong, D.J.3
Kullberg, B.J.4
Adema, G.J.5
-
124
-
-
13244277880
-
Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing
-
Maeda S, et al. Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing. Science 2005 307 : 734 738.
-
(2005)
Science
, vol.307
, pp. 734-738
-
-
Maeda, S.1
-
125
-
-
17944372335
-
CARD15 mutations in Blau syndrome
-
Miceli-Richard C, et al. CARD15 mutations in Blau syndrome. Nat Genet 2001 29 : 19 20.
-
(2001)
Nat Genet
, vol.29
, pp. 19-20
-
-
Miceli-Richard, C.1
-
126
-
-
19944431022
-
Early-onset sarcoidosis and CARD15 mutations with constitutive nuclear factor-kappaB activation: Common genetic etiology with Blau syndrome
-
Kanazawa N, et al. Early-onset sarcoidosis and CARD15 mutations with constitutive nuclear factor-kappaB activation: common genetic etiology with Blau syndrome. Blood 2005 105 : 1195 1197.
-
(2005)
Blood
, vol.105
, pp. 1195-1197
-
-
Kanazawa, N.1
-
127
-
-
20244364812
-
NOD1 variation, immunoglobulin e and asthma
-
Hysi P, et al. NOD1 variation, immunoglobulin E and asthma. Hum Mol Genet 2005 14 : 935 941.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 935-941
-
-
Hysi, P.1
-
128
-
-
21344448610
-
Association of NOD1 polymorphisms with atopic eczema and related phenotypes
-
Weidinger S, et al. Association of NOD1 polymorphisms with atopic eczema and related phenotypes. J Allergy Clin Immunol 2005 116 : 177 184.
-
(2005)
J Allergy Clin Immunol
, vol.116
, pp. 177-184
-
-
Weidinger, S.1
-
129
-
-
0034710643
-
Siblings, day-care attendance, and the risk of asthma and wheezing during childhood
-
Ball TM, Castro-Rodriguez JA, Griffith KA, Holberg CJ, Martinez FD, Wright AL. Siblings, day-care attendance, and the risk of asthma and wheezing during childhood. N Engl J Med 2000 343 : 538 543.
-
(2000)
N Engl J Med
, vol.343
, pp. 538-543
-
-
Ball, T.M.1
Castro-Rodriguez, J.A.2
Griffith, K.A.3
Holberg, C.J.4
Martinez, F.D.5
Wright, A.L.6
-
130
-
-
0035818268
-
Exposure to farming in early life and development of asthma and allergy: A cross-sectional survey
-
Riedler J, et al. Exposure to farming in early life and development of asthma and allergy: a cross-sectional survey. Lancet 2001 358 : 1129 1133.
-
(2001)
Lancet
, vol.358
, pp. 1129-1133
-
-
Riedler, J.1
-
131
-
-
33746846152
-
Association between exposure to farming, allergies and genetic variation in CARD4/NOD1
-
Eder W, et al. Association between exposure to farming, allergies and genetic variation in CARD4/NOD1. Allergy 2006 61 : 1117 1124.
-
(2006)
Allergy
, vol.61
, pp. 1117-1124
-
-
Eder, W.1
-
132
-
-
0032785021
-
Caspase structure, proteolytic substrates, and function during apoptotic cell death
-
Nicholson DW. Caspase structure, proteolytic substrates, and function during apoptotic cell death. Cell Death Differ 1999 6 : 1028 1042.
-
(1999)
Cell Death Differ
, vol.6
, pp. 1028-1042
-
-
Nicholson, D.W.1
-
133
-
-
0026517239
-
Molecular cloning of the interleukin-1 beta converting enzyme
-
Cerretti DP, et al. Molecular cloning of the interleukin-1 beta converting enzyme. Science 1992 256 : 97 100.
-
(1992)
Science
, vol.256
, pp. 97-100
-
-
Cerretti, D.P.1
-
134
-
-
0026507126
-
A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes
-
Thornberry NA, et al. A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes. Nature 1992 356 : 768 774.
-
(1992)
Nature
, vol.356
, pp. 768-774
-
-
Thornberry, N.A.1
-
135
-
-
33845497181
-
Inflammatory caspases and inflammasomes: Master switches of inflammation
-
Martinon F, Tschopp J. Inflammatory caspases and inflammasomes: master switches of inflammation. Cell Death Differ 2007 14 : 10 22.
-
(2007)
Cell Death Differ
, vol.14
, pp. 10-22
-
-
Martinon, F.1
Tschopp, J.2
-
136
-
-
15844393942
-
Activation of the native 45-kDa precursor form of interleukin-1- converting enzyme
-
Yamin TT, Ayala JM, Miller DK. Activation of the native 45-kDa precursor form of interleukin-1-converting enzyme. J Biol Chem 1996 271 : 13273 13282.
-
(1996)
J Biol Chem
, vol.271
, pp. 13273-13282
-
-
Yamin, T.T.1
Ayala, J.M.2
Miller, D.K.3
-
137
-
-
33748501517
-
Nucleotide-binding oligomerization domain-like receptors: Intracellular pattern recognition molecules for pathogen detection and host defense
-
Franchi L, McDonald C, Kanneganti TD, Amer A, Nunez G. Nucleotide-binding oligomerization domain-like receptors: intracellular pattern recognition molecules for pathogen detection and host defense. J Immunol 2006 177 : 3507 3513.
-
(2006)
J Immunol
, vol.177
, pp. 3507-3513
-
-
Franchi, L.1
McDonald, C.2
Kanneganti, T.D.3
Amer, A.4
Nunez, G.5
-
138
-
-
36849045915
-
The inflammasome: A danger sensing complex triggering innate immunity
-
Petrilli V, Dostert C, Muruve DA, Tschopp J. The inflammasome: a danger sensing complex triggering innate immunity. Curr Opin Immunol 2007 19 : 615 622.
-
(2007)
Curr Opin Immunol
, vol.19
, pp. 615-622
-
-
Petrilli, V.1
Dostert, C.2
Muruve, D.A.3
Tschopp, J.4
-
139
-
-
0028920863
-
Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme
-
Kuida K, et al. Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme. Science 1995 267 : 2000 2003.
-
(1995)
Science
, vol.267
, pp. 2000-2003
-
-
Kuida, K.1
-
140
-
-
0028984948
-
Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock
-
Li P, et al. Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock. Cell 1995 80 : 401 411.
-
(1995)
Cell
, vol.80
, pp. 401-411
-
-
Li, P.1
-
141
-
-
0031004174
-
Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production
-
Ghayur T, et al. Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production. Nature 1997 386 : 619 623.
-
(1997)
Nature
, vol.386
, pp. 619-623
-
-
Ghayur, T.1
-
143
-
-
7944232105
-
Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome
-
Martinon F, Agostini L, Meylan E, Tschopp J. Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome. Curr Biol 2004 14 : 1929 1934.
-
(2004)
Curr Biol
, vol.14
, pp. 1929-1934
-
-
Martinon, F.1
Agostini, L.2
Meylan, E.3
Tschopp, J.4
-
144
-
-
0036671894
-
The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
-
Martinon F, Burns K, Tschopp J. The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol Cell 2002 10 : 417 426.
-
(2002)
Mol Cell
, vol.10
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
145
-
-
0035958867
-
Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1
-
Poyet JL, Srinivasula SM, Tnani M, Razmara M, Fernandes-Alnemri T, Alnemri ES. Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1. J Biol Chem 2001 276 : 28309 28313.
-
(2001)
J Biol Chem
, vol.276
, pp. 28309-28313
-
-
Poyet, J.L.1
Srinivasula, S.M.2
Tnani, M.3
Razmara, M.4
Fernandes-Alnemri, T.5
Alnemri, E.S.6
-
146
-
-
0037436868
-
Regulation of cryopyrin/Pypaf1 signaling by pyrin, the familial Mediterranean fever gene product
-
Dowds TA, Masumoto J, Chen FF, Ogura Y, Inohara N, Nunez G. Regulation of cryopyrin/Pypaf1 signaling by pyrin, the familial Mediterranean fever gene product. Biochem Biophys Res Commun 2003 302 : 575 580.
-
(2003)
Biochem Biophys Res Commun
, vol.302
, pp. 575-580
-
-
Dowds, T.A.1
Masumoto, J.2
Chen, F.F.3
Ogura, Y.4
Inohara, N.5
Nunez, G.6
-
147
-
-
18644368579
-
Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF-kappaB and caspase-1
-
Grenier JM, et al. Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF-kappaB and caspase-1. FEBS Lett 2002 530 : 73 78.
-
(2002)
FEBS Lett
, vol.530
, pp. 73-78
-
-
Grenier, J.M.1
-
148
-
-
0010464874
-
PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing
-
Wang L, et al. PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing. J Biol Chem 2002 277 : 29874 29880.
-
(2002)
J Biol Chem
, vol.277
, pp. 29874-29880
-
-
Wang, L.1
-
149
-
-
33744464740
-
Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages
-
Franchi L, et al. Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages. Nat Immunol 2006 7 : 576 582.
-
(2006)
Nat Immunol
, vol.7
, pp. 576-582
-
-
Franchi, L.1
-
150
-
-
33744493091
-
Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf
-
Miao EA, et al. Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf. Nat Immunol 2006 7 : 569 575.
-
(2006)
Nat Immunol
, vol.7
, pp. 569-575
-
-
Miao, E.A.1
-
151
-
-
3142654767
-
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
-
Mariathasan S, et al. Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf. Nature 2004 430 : 213 218.
-
(2004)
Nature
, vol.430
, pp. 213-218
-
-
Mariathasan, S.1
-
152
-
-
34548434775
-
Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages
-
Suzuki T, et al. Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages. PLoS Pathog 2007 3 : e111.
-
(2007)
PLoS Pathog
, vol.3
-
-
Suzuki, T.1
-
153
-
-
40649090426
-
Pseudomonas aeruginosa activates caspase 1 through Ipaf
-
Miao EA, Ernst RK, Dors M, Mao DP, Aderem A. Pseudomonas aeruginosa activates caspase 1 through Ipaf. Proc Natl Acad Sci USA 2008 105 : 2562 2567.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 2562-2567
-
-
Miao, E.A.1
Ernst, R.K.2
Dors, M.3
Mao, D.P.4
Aderem, A.5
-
154
-
-
36248940773
-
Critical role for Ipaf in Pseudomonas aeruginosa-induced caspase-1 activation
-
Franchi L, Stoolman J, Kanneganti TD, Verma A, Ramphal R, Nunez G. Critical role for Ipaf in Pseudomonas aeruginosa-induced caspase-1 activation. Eur J Immunol 2007 37 : 3030 3039.
-
(2007)
Eur J Immunol
, vol.37
, pp. 3030-3039
-
-
Franchi, L.1
Stoolman, J.2
Kanneganti, T.D.3
Verma, A.4
Ramphal, R.5
Nunez, G.6
-
155
-
-
33645770203
-
The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection
-
Zamboni DS, et al. The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection. Nat Immunol 2006 7 : 318 325.
-
(2006)
Nat Immunol
, vol.7
, pp. 318-325
-
-
Zamboni, D.S.1
-
156
-
-
0037470744
-
ASC is an activating adaptor for NF-kappa B and caspase-8-dependent apoptosis
-
Masumoto J, et al. ASC is an activating adaptor for NF-kappa B and caspase-8-dependent apoptosis. Biochem Biophys Res Commun 2003 303 : 69 73.
-
(2003)
Biochem Biophys Res Commun
, vol.303
, pp. 69-73
-
-
Masumoto, J.1
-
157
-
-
33846024748
-
Regulation of Legionella phagosome maturation and infection through flagellin and host Ipaf
-
Amer A, et al. Regulation of Legionella phagosome maturation and infection through flagellin and host Ipaf. J Biol Chem 2006 281 : 35217 35223.
-
(2006)
J Biol Chem
, vol.281
, pp. 35217-35223
-
-
Amer, A.1
-
158
-
-
34247118826
-
Pannexin-1-mediated recognition of bacterial molecules activates the cryopyrin inflammasome independent of Toll-like receptor signaling
-
Kanneganti TD, et al. Pannexin-1-mediated recognition of bacterial molecules activates the cryopyrin inflammasome independent of Toll-like receptor signaling. Immunity 2007 26 : 433 443.
-
(2007)
Immunity
, vol.26
, pp. 433-443
-
-
Kanneganti, T.D.1
-
159
-
-
54049100347
-
The Pseudomonas aeruginosa Type III secretion system plays a dual role in the regulation of Caspase-1 mediated IL-1beta maturation
-
Galle M, et al. The Pseudomonas aeruginosa Type III secretion system plays a dual role in the regulation of Caspase-1 mediated IL-1beta maturation. J Cell Mol Med 2008 11 : 1767 1776.
-
(2008)
J Cell Mol Med
, vol.11
, pp. 1767-1776
-
-
Galle, M.1
-
160
-
-
52549099416
-
Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin
-
Lightfield KL, et al. Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin. Nat Immunol 2008 9 : 1171 1178.
-
(2008)
Nat Immunol
, vol.9
, pp. 1171-1178
-
-
Lightfield, K.L.1
-
161
-
-
37549041954
-
Immune recognition of Pseudomonas aeruginosa mediated by the IPAF/NLRC4 inflammasome
-
Sutterwala FS, Mijares LA, Li L, Ogura Y, Kazmierczak BI, Flavell RA. Immune recognition of Pseudomonas aeruginosa mediated by the IPAF/NLRC4 inflammasome. J Exp Med 2007 204 : 3235 32345.
-
(2007)
J Exp Med
, vol.204
, pp. 3235-32345
-
-
Sutterwala, F.S.1
Mijares, L.A.2
Li, L.3
Ogura, Y.4
Kazmierczak, B.I.5
Flavell, R.A.6
-
162
-
-
36348978900
-
Injection of flagellin into the host cell cytosol by Salmonella enterica serotype Typhimurium
-
Sun YH, Rolan HG, Tsolis RM. Injection of flagellin into the host cell cytosol by Salmonella enterica serotype Typhimurium. J Biol Chem 2007 282 : 33897 33901.
-
(2007)
J Biol Chem
, vol.282
, pp. 33897-33901
-
-
Sun, Y.H.1
Rolan, H.G.2
Tsolis, R.M.3
-
163
-
-
0037178785
-
IRAK-M is a negative regulator of Toll-like receptor signaling
-
Kobayashi K, Hernandez LD, Galan JE, Janeway CA Jr., Medzhitov R, Flavell RA. IRAK-M is a negative regulator of Toll-like receptor signaling. Cell 2002 110 : 191 202.
-
(2002)
Cell
, vol.110
, pp. 191-202
-
-
Kobayashi, K.1
Hernandez, L.D.2
Galan, J.E.3
Janeway Jr., C.A.4
Medzhitov, R.5
Flavell, R.A.6
-
164
-
-
0035937775
-
Molecular cloning and characterization of DEFCAP-L and -S, two isoforms of a novel member of the mammalian Ced-4 family of apoptosis proteins
-
Hlaing T, et al. Molecular cloning and characterization of DEFCAP-L and -S, two isoforms of a novel member of the mammalian Ced-4 family of apoptosis proteins. J Biol Chem 2001 276 : 9230 9238.
-
(2001)
J Biol Chem
, vol.276
, pp. 9230-9238
-
-
Hlaing, T.1
-
165
-
-
33947497237
-
NALP1 in vitiligo-associated multiple autoimmune disease
-
Jin Y, et al. NALP1 in vitiligo-associated multiple autoimmune disease. N Engl J Med 2007 356 : 1216 1225.
-
(2007)
N Engl J Med
, vol.356
, pp. 1216-1225
-
-
Jin, Y.1
-
166
-
-
33847376042
-
Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation
-
Faustin B, et al. Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation. Mol Cell 2007 25 : 713 724.
-
(2007)
Mol Cell
, vol.25
, pp. 713-724
-
-
Faustin, B.1
-
167
-
-
0001616921
-
Anthrax toxin fusion proteins for intracellular delivery of macromolecules
-
Leppla SH, Arora N, Varughese M. Anthrax toxin fusion proteins for intracellular delivery of macromolecules. J Appl Microbiol 1999 87 : 284.
-
(1999)
J Appl Microbiol
, vol.87
, pp. 284
-
-
Leppla, S.H.1
Arora, N.2
Varughese, M.3
-
168
-
-
0031875676
-
Ltx1, a mouse locus that influences the susceptibility of macrophages to cytolysis caused by intoxication with Bacillus anthracis lethal factor, maps to chromosome 11
-
Roberts JE, Watters JW, Ballard JD, Dietrich WF. Ltx1, a mouse locus that influences the susceptibility of macrophages to cytolysis caused by intoxication with Bacillus anthracis lethal factor, maps to chromosome 11. Mol Microbiol 1998 29 : 581 591.
-
(1998)
Mol Microbiol
, vol.29
, pp. 581-591
-
-
Roberts, J.E.1
Watters, J.W.2
Ballard, J.D.3
Dietrich, W.F.4
-
169
-
-
31744441475
-
Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin
-
Boyden ED, Dietrich WF. Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin. Nat Genet 2006 38 : 240 244.
-
(2006)
Nat Genet
, vol.38
, pp. 240-244
-
-
Boyden, E.D.1
Dietrich, W.F.2
-
170
-
-
32944462834
-
Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3
-
Kanneganti TD, et al. Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3. Nature 2006 440 : 233 236.
-
(2006)
Nature
, vol.440
, pp. 233-236
-
-
Kanneganti, T.D.1
-
171
-
-
33846014297
-
Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA
-
Kanneganti TD, et al. Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA. J Biol Chem 2006 281 : 36560 36568.
-
(2006)
J Biol Chem
, vol.281
, pp. 36560-36568
-
-
Kanneganti, T.D.1
-
172
-
-
33644985564
-
Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1
-
Sutterwala FS, et al. Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1. Immunity 2006 24 : 317 327.
-
(2006)
Immunity
, vol.24
, pp. 317-327
-
-
Sutterwala, F.S.1
-
173
-
-
32944470765
-
Cryopyrin activates the inflammasome in response to toxins and ATP
-
Mariathasan S, et al. Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 2006 440 : 228 232.
-
(2006)
Nature
, vol.440
, pp. 228-232
-
-
Mariathasan, S.1
-
174
-
-
43249125839
-
Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
-
Dostert C, Petrilli V, Van Bruggen R, Steele C, Mossman BT, Tschopp J. Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science 2008 320 : 674 677.
-
(2008)
Science
, vol.320
, pp. 674-677
-
-
Dostert, C.1
Petrilli, V.2
Van Bruggen, R.3
Steele, C.4
Mossman, B.T.5
Tschopp, J.6
-
175
-
-
47849132947
-
The Nalp3 inflammasome is essential for the development of silicosis
-
Cassel SL, et al. The Nalp3 inflammasome is essential for the development of silicosis. Proc Natl Acad Sci USA 2008 105 : 9035 9040.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 9035-9040
-
-
Cassel, S.L.1
-
176
-
-
47849097202
-
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
-
Hornung V, et al. Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat Immunol 2008 9 : 847 856.
-
(2008)
Nat Immunol
, vol.9
, pp. 847-856
-
-
Hornung, V.1
-
177
-
-
28244459680
-
Potentiation of caspase-1 activation by the P2X7 receptor is dependent on TLR signals and requires NF-kappaB-driven protein synthesis
-
Kahlenberg JM, Lundberg KC, Kertesy SB, Qu Y, Dubyak GR. Potentiation of caspase-1 activation by the P2X7 receptor is dependent on TLR signals and requires NF-kappaB-driven protein synthesis. J Immunol 2005 175 : 7611 7622.
-
(2005)
J Immunol
, vol.175
, pp. 7611-7622
-
-
Kahlenberg, J.M.1
Lundberg, K.C.2
Kertesy, S.B.3
Qu, Y.4
Dubyak, G.R.5
-
178
-
-
4344700371
-
Differing caspase-1 activation states in monocyte versus macrophage models of IL-1beta processing and release
-
Kahlenberg JM, Dubyak GR. Differing caspase-1 activation states in monocyte versus macrophage models of IL-1beta processing and release. J Leukoc Biol 2004 76 : 676 684.
-
(2004)
J Leukoc Biol
, vol.76
, pp. 676-684
-
-
Kahlenberg, J.M.1
Dubyak, G.R.2
-
179
-
-
0030880696
-
Human monocyte ATP-induced IL-1 beta posttranslational processing is a dynamic process dependent on in vitro growth conditions
-
Laliberte RE, Perregaux DG, McNiff P, Gabel CA. Human monocyte ATP-induced IL-1 beta posttranslational processing is a dynamic process dependent on in vitro growth conditions. J Leukoc Biol 1997 62 : 227 239.
-
(1997)
J Leukoc Biol
, vol.62
, pp. 227-239
-
-
Laliberte, R.E.1
Perregaux, D.G.2
McNiff, P.3
Gabel, C.A.4
-
180
-
-
45849102043
-
ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1beta and IL-18 secretion in an autocrine way
-
Piccini A, Carta S, Tassi S, Lasiglie D, Fossati G, Rubartelli A. ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1beta and IL-18 secretion in an autocrine way. Proc Natl Acad Sci USA 2008 105 : 8067 8072.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 8067-8072
-
-
Piccini, A.1
Carta, S.2
Tassi, S.3
Lasiglie, D.4
Fossati, G.5
Rubartelli, A.6
-
181
-
-
0031054641
-
Purinergic modulation of interleukin-1 beta release from microglial cells stimulated with bacterial endotoxin
-
Ferrari D, Chiozzi P, Falzoni S, Hanau S, Di Virgilio F. Purinergic modulation of interleukin-1 beta release from microglial cells stimulated with bacterial endotoxin. J Exp Med 1997 185 : 579 582.
-
(1997)
J Exp Med
, vol.185
, pp. 579-582
-
-
Ferrari, D.1
Chiozzi, P.2
Falzoni, S.3
Hanau, S.4
Di Virgilio, F.5
-
182
-
-
33646072818
-
The P2X7 receptor: A key player in IL-1 processing and release
-
Ferrari D, et al. The P2X7 receptor: a key player in IL-1 processing and release. J Immunol 2006 176 : 3877 3883.
-
(2006)
J Immunol
, vol.176
, pp. 3877-3883
-
-
Ferrari, D.1
-
183
-
-
0032504212
-
Increased mature interleukin-1beta (IL-1beta) secretion from THP-1 cells induced by nigericin is a result of activation of p45 IL-1beta-converting enzyme processing
-
Cheneval D, et al. Increased mature interleukin-1beta (IL-1beta) secretion from THP-1 cells induced by nigericin is a result of activation of p45 IL-1beta-converting enzyme processing. J Biol Chem 1998 273 : 17846 17851.
-
(1998)
J Biol Chem
, vol.273
, pp. 17846-17851
-
-
Cheneval, D.1
-
184
-
-
28244480768
-
Inhibitory effects of chloride on the activation of caspase-1, IL-1beta secretion, and cytolysis by the P2X7 receptor
-
Verhoef PA, Kertesy SB, Lundberg K, Kahlenberg JM, Dubyak GR. Inhibitory effects of chloride on the activation of caspase-1, IL-1beta secretion, and cytolysis by the P2X7 receptor. J Immunol 2005 175 : 7623 7634.
-
(2005)
J Immunol
, vol.175
, pp. 7623-7634
-
-
Verhoef, P.A.1
Kertesy, S.B.2
Lundberg, K.3
Kahlenberg, J.M.4
Dubyak, G.R.5
-
185
-
-
0042242912
-
2+ in regulation of IL-1beta secretion by P2X7 nucleotide receptor in monocytes, macrophages, and HEK-293 cells
-
2+ in regulation of IL-1beta secretion by P2X7 nucleotide receptor in monocytes, macrophages, and HEK-293 cells. Am J Physiol Cell Physiol 2003 285 : C286 C299.
-
(2003)
Am J Physiol Cell Physiol
, vol.285
-
-
Gudipaty, L.1
Munetz, J.2
Verhoef, P.A.3
Dubyak, G.R.4
-
186
-
-
34547101484
-
Differential requirement of P2X7 receptor and intracellular K+ for caspase-1 activation induced by intracellular and extracellular bacteria
-
Franchi L, Kanneganti TD, Dubyak GR, Nunez G. Differential requirement of P2X7 receptor and intracellular K+ for caspase-1 activation induced by intracellular and extracellular bacteria. J Biol Chem 2007 282 : 18810 18818.
-
(2007)
J Biol Chem
, vol.282
, pp. 18810-18818
-
-
Franchi, L.1
Kanneganti, T.D.2
Dubyak, G.R.3
Nunez, G.4
-
187
-
-
34047270416
-
Pannexin-1 couples to maitotoxin- and nigericin-induced interleukin-1beta release through a dye uptake-independent pathway
-
Pelegrin P, Surprenant A. Pannexin-1 couples to maitotoxin- and nigericin-induced interleukin-1beta release through a dye uptake-independent pathway. J Biol Chem 2007 282 : 2386 2394.
-
(2007)
J Biol Chem
, vol.282
, pp. 2386-2394
-
-
Pelegrin, P.1
Surprenant, A.2
-
188
-
-
33750473352
-
Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor
-
Pelegrin P, Surprenant A. Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor. EMBO J 2006 25 : 5071 5082.
-
(2006)
EMBO J
, vol.25
, pp. 5071-5082
-
-
Pelegrin, P.1
Surprenant, A.2
-
189
-
-
35348932070
-
Intracellular NOD-like receptors in host defense and disease
-
Kanneganti TD, Lamkanfi M, Nunez G. Intracellular NOD-like receptors in host defense and disease. Immunity 2007 27 : 549 559.
-
(2007)
Immunity
, vol.27
, pp. 549-559
-
-
Kanneganti, T.D.1
Lamkanfi, M.2
Nunez, G.3
-
190
-
-
34548027736
-
Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
-
Petrilli V, Papin S, Dostert C, Mayor A, Martinon F, Tschopp J. Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration. Cell Death Differ 2007 14 : 1583 1589.
-
(2007)
Cell Death Differ
, vol.14
, pp. 1583-1589
-
-
Petrilli, V.1
Papin, S.2
Dostert, C.3
Mayor, A.4
Martinon, F.5
Tschopp, J.6
-
191
-
-
38049119726
-
Anthrax lethal toxin-induced inflammasome formation and caspase-1 activation are late events dependent on ion fluxes and the proteasome
-
Wickliffe KE, Leppla SH, Moayeri M. Anthrax lethal toxin-induced inflammasome formation and caspase-1 activation are late events dependent on ion fluxes and the proteasome. Cell Microbiol 2008 10 : 332 343.
-
(2008)
Cell Microbiol
, vol.10
, pp. 332-343
-
-
Wickliffe, K.E.1
Leppla, S.H.2
Moayeri, M.3
-
192
-
-
34848875155
-
Pattern of interleukin-1beta secretion in response to lipopolysaccharide and ATP before and after interleukin-1 blockade in patients with CIAS1 mutations
-
Gattorno M, et al. Pattern of interleukin-1beta secretion in response to lipopolysaccharide and ATP before and after interleukin-1 blockade in patients with CIAS1 mutations. Arthritis Rheum 2007 56 : 3138 3148.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 3138-3148
-
-
Gattorno, M.1
-
193
-
-
0037792866
-
Interleukin-1-receptor antagonist in the Muckle-Wells syndrome
-
Hawkins PN, Lachmann HJ, McDermott MF. Interleukin-1-receptor antagonist in the Muckle-Wells syndrome. N Engl J Med 2003 348 : 2583 2584.
-
(2003)
N Engl J Med
, vol.348
, pp. 2583-2584
-
-
Hawkins, P.N.1
Lachmann, H.J.2
McDermott, M.F.3
-
194
-
-
1042290321
-
Spectrum of clinical features in Muckle-Wells syndrome and response to anakinra
-
Hawkins PN, Lachmann HJ, Aganna E, McDermott MF. Spectrum of clinical features in Muckle-Wells syndrome and response to anakinra. Arthritis Rheum 2004 50 : 607 612.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 607-612
-
-
Hawkins, P.N.1
Lachmann, H.J.2
Aganna, E.3
McDermott, M.F.4
-
195
-
-
0141998606
-
Molecular identification of a danger signal that alerts the immune system to dying cells
-
Shi Y, Evans JE, Rock KL. Molecular identification of a danger signal that alerts the immune system to dying cells. Nature 2003 425 : 516 521.
-
(2003)
Nature
, vol.425
, pp. 516-521
-
-
Shi, Y.1
Evans, J.E.2
Rock, K.L.3
-
196
-
-
32944468985
-
Gout-associated uric acid crystals activate the NALP3 inflammasome
-
Martinon F, Petrilli V, Mayor A, Tardivel A, Tschopp J. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 2006 440 : 237 241.
-
(2006)
Nature
, vol.440
, pp. 237-241
-
-
Martinon, F.1
Petrilli, V.2
Mayor, A.3
Tardivel, A.4
Tschopp, J.5
-
197
-
-
33746747096
-
MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals
-
Chen CJ, et al. MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals. J Clin Invest 2006 116 : 2262 2271.
-
(2006)
J Clin Invest
, vol.116
, pp. 2262-2271
-
-
Chen, C.J.1
-
199
-
-
34247106805
-
Aluminum hydroxide adjuvants activate caspase-1 and induce IL-1beta and IL-18 release
-
Li H, Nookala S, Re F. Aluminum hydroxide adjuvants activate caspase-1 and induce IL-1beta and IL-18 release. J Immunol 2007 178 : 5271 5276.
-
(2007)
J Immunol
, vol.178
, pp. 5271-5276
-
-
Li, H.1
Nookala, S.2
Re, F.3
-
200
-
-
56149119563
-
Cutting Edge: Alum adjuvant stimulates inflammatory dendritic cells through activation of the NALP3 inflammasome
-
Kool M, et al. Cutting Edge: alum adjuvant stimulates inflammatory dendritic cells through activation of the NALP3 inflammasome. J Immunol 2008 181 : 3755 3759.
-
(2008)
J Immunol
, vol.181
, pp. 3755-3759
-
-
Kool, M.1
-
201
-
-
45749111446
-
Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants
-
Eisenbarth SC, Colegio OR, O'Connor W, Sutterwala FS, Flavell RA. Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of
-
(2008)
Nature
, vol.453
, pp. 1122-1126
-
-
Eisenbarth, S.C.1
Colegio, O.R.2
O'Connor, W.3
Sutterwala, F.S.4
Flavell, R.A.5
-
202
-
-
47849087075
-
Cutting edge: Inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3
-
Li H, Willingham SB, Ting JP, Re F. Cutting edge: inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3. J Immunol 2008 181 : 17 21.
-
(2008)
J Immunol
, vol.181
, pp. 17-21
-
-
Li, H.1
Willingham, S.B.2
Ting, J.P.3
Re, F.4
-
203
-
-
50849112477
-
The Nlrp3 inflammasome is critical for aluminium hydroxide-mediated IL-1beta secretion but dispensable for adjuvant activity
-
Franchi L, Nunez G. The Nlrp3 inflammasome is critical for aluminium hydroxide-mediated IL-1beta secretion but dispensable for adjuvant activity. Eur J Immunol 2008 38 : 2085 2089.
-
(2008)
Eur J Immunol
, vol.38
, pp. 2085-2089
-
-
Franchi, L.1
Nunez, G.2
-
204
-
-
33845905223
-
Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling
-
Gavin AL, et al. Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling. Science 2006 314 : 1936 1938.
-
(2006)
Science
, vol.314
, pp. 1936-1938
-
-
Gavin, A.L.1
-
205
-
-
34548699677
-
The role of the inflammasome in cellular responses to toxins and bacterial effectors
-
Freche B, Reig N, van der Goot FG. The role of the inflammasome in cellular responses to toxins and bacterial effectors. Semin Immunopathol 2007 29 : 249 260.
-
(2007)
Semin Immunopathol
, vol.29
, pp. 249-260
-
-
Freche, B.1
Reig, N.2
Van Der Goot, F.G.3
-
206
-
-
33748598700
-
Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival
-
Gurcel L, Abrami L, Girardin S, Tschopp J, van der Goot FG. Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival. Cell 2006 126 : 1135 1145.
-
(2006)
Cell
, vol.126
, pp. 1135-1145
-
-
Gurcel, L.1
Abrami, L.2
Girardin, S.3
Tschopp, J.4
Van Der Goot, F.G.5
-
207
-
-
34047261260
-
ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages
-
Cruz CM, Rinna A, Forman HJ, Ventura AL, Persechini PM, Ojcius DM. ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages. J Biol Chem 2007 282 : 2871 2879.
-
(2007)
J Biol Chem
, vol.282
, pp. 2871-2879
-
-
Cruz, C.M.1
Rinna, A.2
Forman, H.J.3
Ventura, A.L.4
Persechini, P.M.5
Ojcius, D.M.6
-
208
-
-
0028175838
-
Interleukin-1 beta maturation and release in response to ATP and nigericin. Evidence that potassium depletion mediated by these agents is a necessary and common feature of their activity
-
Perregaux D, Gabel CA. Interleukin-1 beta maturation and release in response to ATP and nigericin. Evidence that potassium depletion mediated by these agents is a necessary and common feature of their activity. J Biol Chem 1994 269 : 15195 15203.
-
(1994)
J Biol Chem
, vol.269
, pp. 15195-15203
-
-
Perregaux, D.1
Gabel, C.A.2
-
209
-
-
0028989337
-
Potassium-inhibited processing of IL-1 beta in human monocytes
-
Walev I, Reske K, Palmer M, Valeva A, Bhakdi S. Potassium-inhibited processing of IL-1 beta in human monocytes. EMBO J 1995 14 : 1607 1614.
-
(1995)
EMBO J
, vol.14
, pp. 1607-1614
-
-
Walev, I.1
Reske, K.2
Palmer, M.3
Valeva, A.4
Bhakdi, S.5
-
210
-
-
33646017449
-
Distinct roles of TLR2 and the adaptor ASC in IL-1beta/IL-18 secretion in response to Listeria monocytogenes
-
Ozoren N, et al. Distinct roles of TLR2 and the adaptor ASC in IL-1beta/IL-18 secretion in response to Listeria monocytogenes. J Immunol 2006 176 : 4337 4342.
-
(2006)
J Immunol
, vol.176
, pp. 4337-4342
-
-
Ozoren, N.1
-
211
-
-
47249095738
-
Multiple Nod-like receptors activate caspase 1 during Listeria monocytogenes infection
-
Warren SE, Mao DP, Rodriguez AE, Miao EA, Aderem A. Multiple Nod-like receptors activate caspase 1 during Listeria monocytogenes infection. J Immunol 2008 180 : 7558 7564.
-
(2008)
J Immunol
, vol.180
, pp. 7558-7564
-
-
Warren, S.E.1
Mao, D.P.2
Rodriguez, A.E.3
Miao, E.A.4
Aderem, A.5
-
212
-
-
1042292574
-
Roles of caspase-1 in Listeria infection in mice
-
Tsuji NM, et al. Roles of caspase-1 in Listeria infection in mice. Int Immunol 2004 16 : 335 343.
-
(2004)
Int Immunol
, vol.16
, pp. 335-343
-
-
Tsuji, N.M.1
-
213
-
-
16244362671
-
Apoptosis, pyroptosis, and necrosis: Mechanistic description of dead and dying eukaryotic cells
-
Fink SL, Cookson BT. Apoptosis, pyroptosis, and necrosis: mechanistic description of dead and dying eukaryotic cells. Infect Immun 2005 73 : 1907 1916.
-
(2005)
Infect Immun
, vol.73
, pp. 1907-1916
-
-
Fink, S.L.1
Cookson, B.T.2
-
214
-
-
49949120062
-
Cell death in the host response to infection
-
Labbe K, Saleh M. Cell death in the host response to infection. Cell Death Differ 2008 15 : 1339 1349.
-
(2008)
Cell Death Differ
, vol.15
, pp. 1339-1349
-
-
Labbe, K.1
Saleh, M.2
-
215
-
-
34848866958
-
Pyroptosis and host cell death responses during Salmonella infection
-
Fink SL, Cookson BT. Pyroptosis and host cell death responses during Salmonella infection. Cell Microbiol 2007 9 : 2562 2570.
-
(2007)
Cell Microbiol
, vol.9
, pp. 2562-2570
-
-
Fink, S.L.1
Cookson, B.T.2
-
216
-
-
50949083791
-
Dependency of caspase-1 activation induced in macrophages by Listeria monocytogenes on cytolysin, listeriolysin O, after evasion from phagosome into the cytoplasm
-
Hara H, Tsuchiya K, Nomura T, Kawamura I, Shoma S, Mitsuyama M. Dependency of caspase-1 activation induced in macrophages by Listeria monocytogenes on cytolysin, listeriolysin O, after evasion from phagosome into the cytoplasm. J Immunol 2008 180 : 7859 7868.
-
(2008)
J Immunol
, vol.180
, pp. 7859-7868
-
-
Hara, H.1
Tsuchiya, K.2
Nomura, T.3
Kawamura, I.4
Shoma, S.5
Mitsuyama, M.6
-
217
-
-
41949127121
-
Anthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms
-
Fink SL, Bergsbaken T, Cookson BT. Anthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms. Proc Natl Acad Sci USA 2008 105 : 4312 4317.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 4312-4317
-
-
Fink, S.L.1
Bergsbaken, T.2
Cookson, B.T.3
-
218
-
-
0029665112
-
The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7)
-
Surprenant A, Rassendren F, Kawashima E, North RA, Buell G. The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7). Science 1996 272 : 735 738.
-
(1996)
Science
, vol.272
, pp. 735-738
-
-
Surprenant, A.1
Rassendren, F.2
Kawashima, E.3
North, R.A.4
Buell, G.5
-
219
-
-
0036479134
-
Priming of macrophages with lipopolysaccharide potentiates P2X7-mediated cell death via a caspase-1-dependent mechanism, independently of cytokine production
-
Le Feuvre RA, Brough D, Iwakura Y, Takeda K, Rothwell NJ. Priming of macrophages with lipopolysaccharide potentiates P2X7-mediated cell death via a caspase-1-dependent mechanism, independently of cytokine production. J Biol Chem 2002 277 : 3210 3218.
-
(2002)
J Biol Chem
, vol.277
, pp. 3210-3218
-
-
Le Feuvre, R.A.1
Brough, D.2
Iwakura, Y.3
Takeda, K.4
Rothwell, N.J.5
-
220
-
-
0042914359
-
Critical role for cathepsin B in mediating caspase-1-dependent interleukin-18 maturation and caspase-1-independent necrosis triggered by the microbial toxin nigericin
-
Hentze H, Lin XY, Choi MS, Porter AG. Critical role for cathepsin B in mediating caspase-1-dependent interleukin-18 maturation and caspase-1- independent necrosis triggered by the microbial toxin nigericin. Cell Death Differ 2003 10 : 956 968.
-
(2003)
Cell Death Differ
, vol.10
, pp. 956-968
-
-
Hentze, H.1
Lin, X.Y.2
Choi, M.S.3
Porter, A.G.4
-
221
-
-
34548386663
-
Microbial pathogen-induced necrotic cell death mediated by the inflammasome components CIAS1/cryopyrin/NLRP3 and ASC
-
Willingham SB, et al. Microbial pathogen-induced necrotic cell death mediated by the inflammasome components CIAS1/cryopyrin/NLRP3 and ASC. Cell Host Microbe 2007 2 : 147 159.
-
(2007)
Cell Host Microbe
, vol.2
, pp. 147-159
-
-
Willingham, S.B.1
-
222
-
-
37349046671
-
Macrophage activation redirects yersinia-infected host cell death from apoptosis to caspase-1-dependent pyroptosis
-
Bergsbaken T, Cookson BT. Macrophage activation redirects yersinia-infected host cell death from apoptosis to caspase-1-dependent pyroptosis. PLoS Pathog 2007 3 : e161.
-
(2007)
PLoS Pathog
, vol.3
-
-
Bergsbaken, T.1
Cookson, B.T.2
-
223
-
-
34447643958
-
Toll-like receptor 4 is a sensor for autophagy associated with innate immunity
-
Xu Y, Jagannath C, Liu XD, Sharafkhaneh A, Kolodziejska KE, Eissa NT. Toll-like receptor 4 is a sensor for autophagy associated with innate immunity. Immunity 2007 27 : 135 144.
-
(2007)
Immunity
, vol.27
, pp. 135-144
-
-
Xu, Y.1
Jagannath, C.2
Liu, X.D.3
Sharafkhaneh, A.4
Kolodziejska, K.E.5
Eissa, N.T.6
-
224
-
-
37549043217
-
Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis
-
Sanjuan MA, et al. Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis. Nature 2007 450 : 1253 1257.
-
(2007)
Nature
, vol.450
, pp. 1253-1257
-
-
Sanjuan, M.A.1
-
225
-
-
39849109338
-
Autophagy fights disease through cellular self-digestion
-
Mizushima N, Levine B, Cuervo AM, Klionsky DJ. Autophagy fights disease through cellular self-digestion. Nature 2008 451 : 1069 1075.
-
(2008)
Nature
, vol.451
, pp. 1069-1075
-
-
Mizushima, N.1
Levine, B.2
Cuervo, A.M.3
Klionsky, D.J.4
-
226
-
-
12944308330
-
Eating oneself and uninvited guests: Autophagy-related pathways in cellular defense
-
Levine B. Eating oneself and uninvited guests: autophagy-related pathways in cellular defense. Cell 2005 120 : 159 162.
-
(2005)
Cell
, vol.120
, pp. 159-162
-
-
Levine, B.1
-
227
-
-
33746583965
-
Caspase-1-mediated activation of interleukin-1beta (IL-1beta) and IL-18 contributes to innate immune defenses against Salmonella enterica serovar Typhimurium infection
-
Raupach B, Peuschel SK, Monack DM, Zychlinsky A. Caspase-1-mediated activation of interleukin-1beta (IL-1beta) and IL-18 contributes to innate immune defenses against Salmonella enterica serovar Typhimurium infection. Infect Immun 2006 74 : 4922 4926.
-
(2006)
Infect Immun
, vol.74
, pp. 4922-4926
-
-
Raupach, B.1
Peuschel, S.K.2
Monack, D.M.3
Zychlinsky, A.4
-
228
-
-
33745012076
-
Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis
-
Lara-Tejero M, et al. Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis. J Exp Med 2006 203 : 1407 1412.
-
(2006)
J Exp Med
, vol.203
, pp. 1407-1412
-
-
Lara-Tejero, M.1
-
229
-
-
0033679111
-
Caspase-1 activation of IL-1beta and IL-18 are essential for Shigella flexneri-induced inflammation
-
Sansonetti PJ, et al. Caspase-1 activation of IL-1beta and IL-18 are essential for Shigella flexneri-induced inflammation. Immunity 2000 12 : 581 590.
-
(2000)
Immunity
, vol.12
, pp. 581-590
-
-
Sansonetti, P.J.1
-
230
-
-
26844452231
-
Innate immunity against Francisella tularensis is dependent on the ASC/caspase-1 axis
-
Mariathasan S, Weiss DS, Dixit VM, Monack DM. Innate immunity against Francisella tularensis is dependent on the ASC/caspase-1 axis. J Exp Med 2005 202 : 1043 1049.
-
(2005)
J Exp Med
, vol.202
, pp. 1043-1049
-
-
Mariathasan, S.1
Weiss, D.S.2
Dixit, V.M.3
Monack, D.M.4
-
231
-
-
33845478357
-
The inflammatory caspases: Guardians against infections and sepsis
-
Scott AM, Saleh M. The inflammatory caspases: guardians against infections and sepsis. Cell Death Differ 2007 14 : 23 31.
-
(2007)
Cell Death Differ
, vol.14
, pp. 23-31
-
-
Scott, A.M.1
Saleh, M.2
-
232
-
-
0038557053
-
Phagocyte sabotage: Disruption of macrophage signalling by bacterial pathogens
-
Rosenberger CM, Finlay BB. Phagocyte sabotage: disruption of macrophage signalling by bacterial pathogens. Nat Rev Mol Cell Biol 2003 4 : 385 396.
-
(2003)
Nat Rev Mol Cell Biol
, vol.4
, pp. 385-396
-
-
Rosenberger, C.M.1
Finlay, B.B.2
-
233
-
-
2342525996
-
Regulation of phagosome maturation by signals from toll-like receptors
-
Blander JM, Medzhitov R. Regulation of phagosome maturation by signals from toll-like receptors. Science 2004 304 : 1014 1018.
-
(2004)
Science
, vol.304
, pp. 1014-1018
-
-
Blander, J.M.1
Medzhitov, R.2
-
234
-
-
33748848754
-
On regulation of phagosome maturation and antigen presentation
-
Blander JM, Medzhitov R. On regulation of phagosome maturation and antigen presentation. Nat Immunol 2006 7 : 1029 1035.
-
(2006)
Nat Immunol
, vol.7
, pp. 1029-1035
-
-
Blander, J.M.1
Medzhitov, R.2
-
235
-
-
33645843633
-
Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection
-
Molofsky AB, et al. Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection. J Exp Med 2006 203 : 1093 1104.
-
(2006)
J Exp Med
, vol.203
, pp. 1093-1104
-
-
Molofsky, A.B.1
-
236
-
-
48749097539
-
ESX-1-dependent cytolysis in lysosome secretion and inflammasome activation during mycobacterial infection
-
Koo IC, Wang C, Raghavan S, Morisaki JH, Cox JS, Brown EJ. ESX-1-dependent cytolysis in lysosome secretion and inflammasome activation during mycobacterial infection. Cell Microbiol 2008 10 : 1866 1878.
-
(2008)
Cell Microbiol
, vol.10
, pp. 1866-1878
-
-
Koo, I.C.1
Wang, C.2
Raghavan, S.3
Morisaki, J.H.4
Cox, J.S.5
Brown, E.J.6
-
237
-
-
41849104578
-
Mycobacterium tuberculosis prevents inflammasome activation
-
Master SS, et al. Mycobacterium tuberculosis prevents inflammasome activation. Cell Host Microbe 2008 3 : 224 232.
-
(2008)
Cell Host Microbe
, vol.3
, pp. 224-232
-
-
Master, S.S.1
|