NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal α-defensin expression

Gut

Volumn 53, Issue 11, 2004, Pages 1658-1664

  Wehkamp, J ^a   Harder, J ^c   Weichenthal, M ^c   Schwab, M ^b   Schaffeler E ^b   Schlee, M ^a   Herrlinger, K R ^a   Stallmach, A ^e   Noack, F ^d   Fritz, P ^a   Schroder J M ^c   Bevins, C L ^f   Fellermann, K ^a   Stange, E F ^a  

^a ROBERT BOSCH HOSPITAL   (Germany)

^b DR MARGARETE FISCHER BOSCH INSTITUTE OF CLINICAL PHARMACOLOGY   (Germany)

^c UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^d UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^e SAARLAND UNIVERSITY   (Germany)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA DEFENSIN; CASPASE RECRUITMENT DOMAIN PROTEIN 15; CELL RECEPTOR; DEFENSIN; HUMAN DEFENSIN 5; HUMAN DEFENSIN 6; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; INTERLEUKIN 8; LYSOZYME; MESSENGER RNA; PEPTIDOGLYCAN; PHOSPHOLIPASE A2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CROHN DISEASE; GENE EXPRESSION; GENE MUTATION; GENOTYPE; HOUSEKEEPING GENE; HUMAN; HUMAN TISSUE; ILEUM; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INTESTINE MUCOSA; PANETH CELL; PATHOGENESIS; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STAINING; WILD TYPE;

ADOLESCENT; ADULT; AGED; ALPHA-DEFENSINS; COLON; CROHN DISEASE; DNA MUTATIONAL ANALYSIS; GENE EXPRESSION REGULATION; HUMANS; ILEUM; IMMUNITY, MUCOSAL; INTERLEUKIN-8; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MIDDLE AGED; MUTATION; NOD2 SIGNALING ADAPTOR PROTEIN; PANETH CELLS; POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

EID: 7244257312     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.2003.032805     Document Type: Article

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