메뉴 건너뛰기




Volumn 73, Issue 12, 2005, Pages 7967-7976

Synergistic effect of Nod1 and Nod2 agonists with toll-like receptor agonists on human dendritic cells to generate interleukin-12 and T helper type 1 cells

Author keywords

[No Author keywords available]

Indexed keywords

[2,3 BIS(PALMITOYLOXY)PROPYL] N PALMITOYLPENTAPEPTIDE; ADJUVANT; CASPASE RECRUITMENT DOMAIN PROTEIN 15; CYTOKINE; DNA; GAMMA INTERFERON; GLUDAPCIN; HEPTANOYL GAMMA DEXTRO GLUTAMYL 2,6 DIAMINOPIMELOYL DEXTRO ALANINE; IMMUNOMODULATING AGENT; INTERLEUKIN 12; INTERLEUKIN 15; INTERLEUKIN 18; LIPID A; LIPOPEPTIDE; MURAMYL DIPEPTIDE; NOD1 AGONIST; NOD2 AGONIST; PEPTIDOGLYCAN; POLYINOSINIC POLYCYTIDYLIC ACID; PROTEIN NOD1; PROTEIN P70; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 2 AGONIST; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 3 AGONIST; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 9; TOLL LIKE RECEPTOR 9 AGONIST; TOLL LIKE RECEPTOR AGONIST; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 28444471235     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.73.12.7967-7976.2005     Document Type: Article
Times cited : (310)

References (51)
  • 1
    • 28444446958 scopus 로고
    • John Wiley & Sons, New York, N.Y.
    • Adam, A. 1985. Synthetic adjuvants. John Wiley & Sons, New York, N.Y.
    • (1985) Synthetic Adjuvants
    • Adam, A.1
  • 2
    • 0242580118 scopus 로고    scopus 로고
    • Different Toll-like receptor agonists instruct dendritic cells to induce distinct Th responses via differential modulation of extracellular signal-regulated kinase-mitogen-activated protein kinase and c-Fos
    • Agrawal, S., A. Agrawal, B. Doughty, A. Gerwitz, J. Blenis, T. Van Dyke, and B. Pulendran. 2003. Different Toll-like receptor agonists instruct dendritic cells to induce distinct Th responses via differential modulation of extracellular signal-regulated kinase-mitogen-activated protein kinase and c-Fos. J. Immunol. 171:4984-4989.
    • (2003) J. Immunol. , vol.171 , pp. 4984-4989
    • Agrawal, S.1    Agrawal, A.2    Doughty, B.3    Gerwitz, A.4    Blenis, J.5    Van Dyke, T.6    Pulendran, B.7
  • 3
    • 0034671944 scopus 로고    scopus 로고
    • CpG DNA induces maturation of dendritic cells with distinct effects on nascent and recycling MHC-II antigen-processing mechanisms
    • Askew, D., R. S. Chu, A. M. Krieg, and C. V. Harding. 2000. CpG DNA induces maturation of dendritic cells with distinct effects on nascent and recycling MHC-II antigen-processing mechanisms. J. Immunol. 165:6889-6895.
    • (2000) J. Immunol. , vol.165 , pp. 6889-6895
    • Askew, D.1    Chu, R.S.2    Krieg, A.M.3    Harding, C.V.4
  • 4
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau, J., and R. M. Steinman. 1998. Dendritic cells and the control of immunity. Nature 392:245-252.
    • (1998) Nature , vol.392 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 5
    • 0020163646 scopus 로고
    • B-lymphocyte mitogenicity in vitro of a synthetic lipopeptide fragment derived from bacterial lipoprotein
    • Bessler, W. G., R. B. Johnson, K. Wiesmüller, and G. Jung. 1982. B-lymphocyte mitogenicity in vitro of a synthetic lipopeptide fragment derived from bacterial lipoprotein. Hoppe-Seyler's Z. Physiol. Chem. 363:767-770.
    • (1982) Hoppe-Seyler's Z. Physiol. Chem. , vol.363 , pp. 767-770
    • Bessler, W.G.1    Johnson, R.B.2    Wiesmüller, K.3    Jung, G.4
  • 6
    • 0030586560 scopus 로고    scopus 로고
    • A direct role for IFN-γ in regulation of Th1 cell development
    • Bradley, L. M., D. K. Dalton, and M. Croft. 1996. A direct role for IFN-γ in regulation of Th1 cell development. J. Immunol. 157:1350-1358.
    • (1996) J. Immunol. , vol.157 , pp. 1350-1358
    • Bradley, L.M.1    Dalton, D.K.2    Croft, M.3
  • 8
    • 0016200846 scopus 로고
    • Minimal structural requirements for adjuvant activity of bacterial peptidoglycan derivatives
    • Ellouz, F., A. Adam, R. Ciorbaru, and E. Lederer. 1974. Minimal structural requirements for adjuvant activity of bacterial peptidoglycan derivatives. Biochem. Biophys. Res. Commun. 59:1317-1325.
    • (1974) Biochem. Biophys. Res. Commun. , vol.59 , pp. 1317-1325
    • Ellouz, F.1    Adam, A.2    Ciorbaru, R.3    Lederer, E.4
  • 9
    • 0016330533 scopus 로고
    • Adjuvant activity in delayed hypersensitivity of the peptidic part of bacterial peptidoglycans
    • Fleck, J., M. Mock, F. Tytgat, C. Nauciel, and R. Minck. 1974. Adjuvant activity in delayed hypersensitivity of the peptidic part of bacterial peptidoglycans. Nature 250:517-518.
    • (1974) Nature , vol.250 , pp. 517-518
    • Fleck, J.1    Mock, M.2    Tytgat, F.3    Nauciel, C.4    Minck, R.5
  • 10
    • 84954971084 scopus 로고
    • Sensitization to horse serum by means of adjuvants
    • Freund, J., and K. McDermott. 1942. Sensitization to horse serum by means of adjuvants. Proc. Soc. Exp. Biol. Med. 49:548-553.
    • (1942) Proc. Soc. Exp. Biol. Med. , vol.49 , pp. 548-553
    • Freund, J.1    McDermott, K.2
  • 13
    • 4243643363 scopus 로고
    • The immunomodulatory activities of acylpeptides
    • I. Azuma and G. Jollès (ed.). Japan Science Society Press, Tokyo, Japan
    • Goto, T., and H. Aoki. 1987. The immunomodulatory activities of acylpeptides, p. 99-108. In I. Azuma and G. Jollès (ed.), Immunostimulants: now and tomorrow. Japan Science Society Press, Tokyo, Japan.
    • (1987) Immunostimulants: Now and Tomorrow , pp. 99-108
    • Goto, T.1    Aoki, H.2
  • 14
    • 0035886848 scopus 로고    scopus 로고
    • Rel regulates interleukin 12 p70 expression in CD8+ dendritic cells by specifically inducing p35 gene transcription
    • Grumont, R., H. Hochrein, M. O'Keeffe, R. Gugasyan, C. White, I. Caminschi, W. Cook, and S. Gerondakis. 2001. c-Rel regulates interleukin 12 p70 expression in CD8+ dendritic cells by specifically inducing p35 gene transcription. J. Exp. Med. 194:1021-1031.
    • (2001) J. Exp. Med. , vol.194 , pp. 1021-1031
    • Grumont, R.1    Hochrein, H.2    O'Keeffe, M.3    Gugasyan, R.4    White, C.5    Caminschi, I.6    Cook, W.7    Gerondakis, S.8
  • 16
    • 0035951792 scopus 로고    scopus 로고
    • Human Nod1 confers responsiveness to bacterial lipopolysaccharides
    • Inohara, N., Y. Ogura, F. F. Chen, A. Muto, and G. Nuñez. 2001. Human Nod1 confers responsiveness to bacterial lipopolysaccharides. J. Biol. Chem. 276:2551-2554.
    • (2001) J. Biol. Chem. , vol.276 , pp. 2551-2554
    • Inohara, N.1    Ogura, Y.2    Chen, F.F.3    Muto, A.4    Nuñez, G.5
  • 18
    • 0035284744 scopus 로고    scopus 로고
    • Differential regulation of human blood dendritic cell subsets by IFNs
    • Ito, T., R. Amakawa, M. Inaba, S. Ikehara, K. Inaba, and S. Fukuhara. 2001. Differential regulation of human blood dendritic cell subsets by IFNs. J. Immunol. 166:2961-2969.
    • (2001) J. Immunol. , vol.166 , pp. 2961-2969
    • Ito, T.1    Amakawa, R.2    Inaba, M.3    Ikehara, S.4    Inaba, K.5    Fukuhara, S.6
  • 19
    • 5444262511 scopus 로고    scopus 로고
    • Toll-like receptor control of the adaptive immune responses
    • Iwasaki, A., and R. Medzhitov. 2004. Toll-like receptor control of the adaptive immune responses. Nat. Immunol. 5:987-995.
    • (2004) Nat. Immunol. , vol.5 , pp. 987-995
    • Iwasaki, A.1    Medzhitov, R.2
  • 20
    • 0346146996 scopus 로고    scopus 로고
    • Regulation of dendritic cell function through Toll-like receptors
    • Kaisho, T., and S. Akira. 2003. Regulation of dendritic cell function through Toll-like receptors. Curr. Mol. Med. 3:373-385.
    • (2003) Curr. Mol. Med. , vol.3 , pp. 373-385
    • Kaisho, T.1    Akira, S.2
  • 21
    • 0345346375 scopus 로고    scopus 로고
    • Final maturation of dendritic cells is associated with impaired responsiveness to IFN-γ and to bacterial IL-12 inducers: Decreased ability of mature dendritic cells to produce IL-12 during the interaction with Th cells
    • Kalinski, P., J. H. N. Schuitemaker, C. M. U. Hilkens, E. A. Wierenga, and M. L. Kapsenberg. 1999. Final maturation of dendritic cells is associated with impaired responsiveness to IFN-γ and to bacterial IL-12 inducers: decreased ability of mature dendritic cells to produce IL-12 during the interaction with Th cells. J. Immunol. 162:3231-3236.
    • (1999) J. Immunol. , vol.162 , pp. 3231-3236
    • Kalinski, P.1    Schuitemaker, J.H.N.2    Hilkens, C.M.U.3    Wierenga, E.A.4    Kapsenberg, M.L.5
  • 22
  • 23
    • 1642268316 scopus 로고    scopus 로고
    • Innate immune system discriminates between RNA containing bacterial versus eukaryotic structural features that prime for high-level IL-12 secretion by dendritic cells
    • Koski, G. K., K. Karikó, S. Xu, D. Weissman, P. A. Cohen, and B. J. Czerniecki. 2004. Innate immune system discriminates between RNA containing bacterial versus eukaryotic structural features that prime for high-level IL-12 secretion by dendritic cells. J. Immunol. 172:3989-3993.
    • (2004) J. Immunol. , vol.172 , pp. 3989-3993
    • Koski, G.K.1    Karikó, K.2    Xu, S.3    Weissman, D.4    Cohen, P.A.5    Czerniecki, B.J.6
  • 26
    • 0034670053 scopus 로고    scopus 로고
    • A subset of human monocyte-derived dendritic cells expresses high levels of interleukin-12 in response to combined CD40 ligand and interferon-γ treatment
    • Mosca, P. J., A. C. Hobeika, T. M. Clay, S. K. Nair, E. K. Thomas, M. A. Morse, and H. K. Lyerly. 2000. A subset of human monocyte-derived dendritic cells expresses high levels of interleukin-12 in response to combined CD40 ligand and interferon-γ treatment. Blood 96:3499-3504.
    • (2000) Blood , vol.96 , pp. 3499-3504
    • Mosca, P.J.1    Hobeika, A.C.2    Clay, T.M.3    Nair, S.K.4    Thomas, E.K.5    Morse, M.A.6    Lyerly, H.K.7
  • 28
    • 0036467440 scopus 로고    scopus 로고
    • Synergy of IL-12 and IL-18 for IFN-γ gene expression: IL-12-induced STAT4 contributes to IFN-7 promoter activation by up-regulating the binding activity of IL-18-induced activator protein 1
    • Nakahira, M., H.-J. Ahn, W.-R. Park, P. Gao, M. Tomura, C.-S. Park, T. Hamaoka, T. Ohta, M. Kurimoto, and H. Fujiwara. 2002. Synergy of IL-12 and IL-18 for IFN-γ gene expression: IL-12-induced STAT4 contributes to IFN-7 promoter activation by up-regulating the binding activity of IL-18-induced activator protein 1. J. Immunol. 168:1146-1153.
    • (2002) J. Immunol. , vol.168 , pp. 1146-1153
    • Nakahira, M.1    Ahn, H.-J.2    Park, W.-R.3    Gao, P.4    Tomura, M.5    Park, C.-S.6    Hamaoka, T.7    Ohta, T.8    Kurimoto, M.9    Fujiwara, H.10
  • 29
    • 0036214502 scopus 로고    scopus 로고
    • Signaling pathways induced by lipoproteins derived from Mycoplasma salivarium and a synthetic lipopeptide (FSL-1) in normal human gingival fibroblasts
    • Nakamura, J., K. Shibata, A. Hasebe, T. Into, T. Watanabe, and N. Ohata. 2002. Signaling pathways induced by lipoproteins derived from Mycoplasma salivarium and a synthetic lipopeptide (FSL-1) in normal human gingival fibroblasts. Microbiol. Immunol. 46:151-158.
    • (2002) Microbiol. Immunol. , vol.46 , pp. 151-158
    • Nakamura, J.1    Shibata, K.2    Hasebe, A.3    Into, T.4    Watanabe, T.5    Ohata, N.6
  • 30
    • 0036177482 scopus 로고    scopus 로고
    • + T cells proliferation but is unable to drive cytokine production in the absence of TCR activation or IL-12/IL-4 stimulation in vitro
    • + T cells proliferation but is unable to drive cytokine production in the absence of TCR activation or IL-12/IL-4 stimulation in vitro. Eur. J. Immunol. 32:341-347.
    • (2002) Eur. J. Immunol. , vol.32 , pp. 341-347
    • Niedbala, W.1    Wei, X.2    Liew, F.Y.3
  • 31
    • 0035813157 scopus 로고    scopus 로고
    • Toll-like receptor 2 (TLR2) and TLR4 differentially activate human dendritic cells
    • Re, F., and J. L. Strominger. 2001. Toll-like receptor 2 (TLR2) and TLR4 differentially activate human dendritic cells. J. Biol. Chem. 276:37692-37699.
    • (2001) J. Biol. Chem. , vol.276 , pp. 37692-37699
    • Re, F.1    Strominger, J.L.2
  • 32
    • 10344243503 scopus 로고    scopus 로고
    • IL-10 released by concomitant TLR2 stimulation blocks the induction of a subset of Th1 cytokines that are specifically induced by TLR4 or TLR3 in human dendritic cells
    • Re, F., and J. L. Strominger. 2004. IL-10 released by concomitant TLR2 stimulation blocks the induction of a subset of Th1 cytokines that are specifically induced by TLR4 or TLR3 in human dendritic cells. J. Immunol. 173:7548-7555.
    • (2004) J. Immunol. , vol.173 , pp. 7548-7555
    • Re, F.1    Strominger, J.L.2
  • 33
    • 1342324768 scopus 로고    scopus 로고
    • Activation of Toll-like receptor 2 induces a Th2 immune response and promotes experimental asthma
    • Redecke, V., H. Häcker, S. K. Datta, A. Fermin, P. M. Pitha, D. H. Broide, and E. Raz. 2004. Activation of Toll-like receptor 2 induces a Th2 immune response and promotes experimental asthma. J. Immunol. 172:2739-2743.
    • (2004) J. Immunol. , vol.172 , pp. 2739-2743
    • Redecke, V.1    Häcker, H.2    Datta, S.K.3    Fermin, A.4    Pitha, P.M.5    Broide, D.H.6    Raz, E.7
  • 34
    • 0015462556 scopus 로고
    • Peptidoglycan types of bacterial cell walls and their taxonomic implications
    • Schleifer, K. H., and O. Kandler. 1972. Peptidoglycan types of bacterial cell walls and their taxonomic implications. Bacteriol. Rev. 36:407-477.
    • (1972) Bacteriol. Rev. , vol.36 , pp. 407-477
    • Schleifer, K.H.1    Kandler, O.2
  • 35
    • 0033580949 scopus 로고    scopus 로고
    • Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by Toll-like receptor 2
    • Schwandner, R., R. Dziarski, H. Wesche, M. Rothe, and C. J. Kirschning. 1999. Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by Toll-like receptor 2. J. Biol. Chem. 274:17406-17409.
    • (1999) J. Biol. Chem. , vol.274 , pp. 17406-17409
    • Schwandner, R.1    Dziarski, R.2    Wesche, H.3    Rothe, M.4    Kirschning, C.J.5
  • 36
    • 0031725838 scopus 로고    scopus 로고
    • High-level IL-12 production by human dendritic cells requires two signals
    • Snijders, A., P. Kalinski, C. M. U. Hilkens, and M. L. Kapsenberg. 1998. High-level IL-12 production by human dendritic cells requires two signals. Int. Immunol. 10:1593-1598.
    • (1998) Int. Immunol. , vol.10 , pp. 1593-1598
    • Snijders, A.1    Kalinski, P.2    Hilkens, C.M.U.3    Kapsenberg, M.L.4
  • 37
    • 12444269681 scopus 로고
    • Immunopotentiating activity of peptidoglycan and surface polymers
    • D. E. S. Stewart-Tull and M. Davis (ed.). John Wiley & Sons, Chichester, United Kingdom
    • Stewart-Tull, D. E. S. 1985. Immunopotentiating activity of peptidoglycan and surface polymers, p. 47-89. In D. E. S. Stewart-Tull and M. Davis (ed.), Immunology of the bacterial cell envelope. John Wiley & Sons, Chichester, United Kingdom.
    • (1985) Immunology of the Bacterial Cell Envelope , pp. 47-89
    • Stewart-Tull, D.E.S.1
  • 38
    • 0031705349 scopus 로고    scopus 로고
    • Production of functional IL-18 by different subtypes of murine and human dendritic cells (DC): DC-derived IL-18 enhances IL-12-dependent Th1 development
    • Stoll, S., H. Jonuleit, E. Schmitt, G. Müller, H. Yamauchi, M. Kurimoto, J. Knop, and A. H. Enk. 1998. Production of functional IL-18 by different subtypes of murine and human dendritic cells (DC): DC-derived IL-18 enhances IL-12-dependent Th1 development. Eur. J. Immunol. 28:3231-3239.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 3231-3239
    • Stoll, S.1    Jonuleit, H.2    Schmitt, E.3    Müller, G.4    Yamauchi, H.5    Kurimoto, M.6    Knop, J.7    Enk, A.H.8
  • 39
    • 0000350353 scopus 로고
    • Immunopharmacological activities of synthetic muramyl-peptides
    • D. E. S. Stewart-Tull and M. Davies (ed.). John Wiley & Sons, Chichester, United Kingdom
    • Takada, H., and S. Kotani. 1985. Immunopharmacological activities of synthetic muramyl-peptides, p. 119-152. In D. E. S. Stewart-Tull and M. Davies (ed.), Immunology of the bacterial cell envelope. John Wiley & Sons, Chichester, United Kingdom.
    • (1985) Immunology of the Bacterial Cell Envelope , pp. 119-152
    • Takada, H.1    Kotani, S.2
  • 40
    • 0000675671 scopus 로고
    • Muramyl dipeptide and derivatives
    • D. E. S. Stewart-Tull (ed.). John Wiley & Sons, Chichester, United Kingdom
    • Takada, H., and S. Kotani. 1995. Muramyl dipeptide and derivatives, p. 171-202. In D. E. S. Stewart-Tull (ed.), The theory and practical application of adjuvants. John Wiley & Sons, Chichester, United Kingdom.
    • (1995) The Theory and Practical Application of Adjuvants , pp. 171-202
    • Takada, H.1    Kotani, S.2
  • 41
    • 0036453023 scopus 로고    scopus 로고
    • Enhancement of endotoxin activity by muramyldipeptide
    • Takada, H., S. Yokoyama, and S. Yang. 2002. Enhancement of endotoxin activity by muramyldipeptide. J. Endotoxin Res. 8:337-342.
    • (2002) J. Endotoxin Res. , vol.8 , pp. 337-342
    • Takada, H.1    Yokoyama, S.2    Yang, S.3
  • 42
    • 0033213590 scopus 로고    scopus 로고
    • Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components
    • Takeuchi, O., K. Hoshino, T. Kawai, H. Sanjo, H. Takada, T. Ogawa, K. Takeda, and S. Akira. 1999. Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components. Immunity 11:443-451.
    • (1999) Immunity , vol.11 , pp. 443-451
    • Takeuchi, O.1    Hoshino, K.2    Kawai, T.3    Sanjo, H.4    Takada, H.5    Ogawa, T.6    Takeda, K.7    Akira, S.8
  • 43
    • 43949163341 scopus 로고
    • Interleukin-12 and its role in the regulation of Th1 cells
    • Trinchieri, G. 1993. Interleukin-12 and its role in the regulation of Th1 cells. Immunol. Today 14:335-338.
    • (1993) Immunol. Today , vol.14 , pp. 335-338
    • Trinchieri, G.1
  • 44
    • 0028970060 scopus 로고
    • Interleukin-12: A proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity
    • Trinchieri, G. 1995. Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu. Rev. Immunol. 13:251-276.
    • (1995) Annu. Rev. Immunol. , vol.13 , pp. 251-276
    • Trinchieri, G.1
  • 45
    • 12444259829 scopus 로고    scopus 로고
    • Muramyldipeptide and diaminopimelic acid-containing desmuramylpeptides in combination with chemically synthesized Toll-like receptor agonists synergistically induced production of interleukin-8 in a NOD2- And NOD1-dependent manner, respectively, in human monocytic cells in culture
    • Uehara, A., S. Yang, Y. Fujimoto, K. Fukase, S. Kusumoto, K. Shibata, S. Sugawara, and H. Takada. 2005. Muramyldipeptide and diaminopimelic acid-containing desmuramylpeptides in combination with chemically synthesized Toll-like receptor agonists synergistically induced production of interleukin-8 in a NOD2- and NOD1-dependent manner, respectively, in human monocytic cells in culture. Cell. Microbiol. 7:53-61.
    • (2005) Cell. Microbiol. , vol.7 , pp. 53-61
    • Uehara, A.1    Yang, S.2    Fujimoto, Y.3    Fukase, K.4    Kusumoto, S.5    Shibata, K.6    Sugawara, S.7    Takada, H.8
  • 46
    • 0034938974 scopus 로고    scopus 로고
    • Macrophage stimulation with murabutide, an HIV-suppressive muramyl peptide derivative, selectively activates extracellular signal-regulated kinases 1 and 2, C/EBPβ and STAT1: Role of CD14 and Toll-like receptor 2 and 4
    • Vidal, V. F., N. Castéran, C. J. Riendeau, H. Kornfeld, E. C. A. Darcissac, A. Capron, and G. M. Bahr. 2001. Macrophage stimulation with murabutide, an HIV-suppressive muramyl peptide derivative, selectively activates extracellular signal-regulated kinases 1 and 2, C/EBPβ and STAT1: role of CD14 and Toll-like receptor 2 and 4. Eur. J. Immunol. 31:1962-1971.
    • (2001) Eur. J. Immunol. , vol.31 , pp. 1962-1971
    • Vidal, V.F.1    Castéran, N.2    Riendeau, C.J.3    Kornfeld, H.4    Darcissac, E.C.A.5    Capron, A.6    Bahr, G.M.7
  • 47
    • 4444253690 scopus 로고    scopus 로고
    • NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses
    • Watanabe, T., A. Kitani, P. J. Murray, and W. Strober. 2004. NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses. Nat. Immunol. 5:800-808.
    • (2004) Nat. Immunol. , vol.5 , pp. 800-808
    • Watanabe, T.1    Kitani, A.2    Murray, P.J.3    Strober, W.4
  • 48
    • 0020755487 scopus 로고
    • Synthesis of the mitogenic S-[2,3-bis(palmitoyloxy)propyl]-N- palmitoylpentapeptide from Escherichia coli lipoprotein
    • Wiesmüller, K.-H., W. Bessler, and G. Jung. 1983. Synthesis of the mitogenic S-[2,3-bis(palmitoyloxy)propyl]-N-palmitoylpentapeptide from Escherichia coli lipoprotein. Hoppe Seyler's Z. Physiol. Chem. 364:593-606.
    • (1983) Hoppe Seyler's Z. Physiol. Chem. , vol.364 , pp. 593-606
    • Wiesmüller, K.-H.1    Bessler, W.2    Jung, G.3
  • 49
    • 0037131232 scopus 로고    scopus 로고
    • The origin of the synergistic effect of muramyl dipeptide with endotoxin and peptidoglycan
    • Wolfert, M. A., T. F. Murray, G.-J. Boons, and J. N. Moore. 2002. The origin of the synergistic effect of muramyl dipeptide with endotoxin and peptidoglycan. J. Biol. Chem. 277:39179-39186.
    • (2002) J. Biol. Chem. , vol.277 , pp. 39179-39186
    • Wolfert, M.A.1    Murray, T.F.2    Boons, G.-J.3    Moore, J.N.4
  • 50
    • 0035078190 scopus 로고    scopus 로고
    • Synergistic effect of muramyldipeptide with lipopolysaccharide or lipoteichoic acid to induce inflammatory cytokines in human monocytic cells in culture
    • Yang, S., R. Tamai, S. Akashi, O. Takeuchi, S. Akira, S. Sugawara, and H. Takada. 2001. Synergistic effect of muramyldipeptide with lipopolysaccharide or lipoteichoic acid to induce inflammatory cytokines in human monocytic cells in culture. Infect. Immun. 69:2045-2053.
    • (2001) Infect. Immun. , vol.69 , pp. 2045-2053
    • Yang, S.1    Tamai, R.2    Akashi, S.3    Takeuchi, O.4    Akira, S.5    Sugawara, S.6    Takada, H.7
  • 51
    • 0033168728 scopus 로고    scopus 로고
    • Recognition of gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2
    • Yoshimura, A., E. Lien, R. R. Ingalls, E. Tuomanen, R. Dziarski, and D. Golenbock. 1999. Recognition of gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2. J. Immunol. 163:1-5.
    • (1999) J. Immunol. , vol.163 , pp. 1-5
    • Yoshimura, A.1    Lien, E.2    Ingalls, R.R.3    Tuomanen, E.4    Dziarski, R.5    Golenbock, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.