메뉴 건너뛰기




Volumn 181, Issue 6, 2008, Pages 3755-3759

Cutting edge: Alum adjuvant stimulates inflammatory dendritic cells through activation of the NALP3 inflammasome

Author keywords

[No Author keywords available]

Indexed keywords

ALUM ADJUVANT; ALUMINUM MAGNESIUM HYDROXIDE; ANTIGEN; CRYOPYRIN; IMJECT ALUM; IMMUNOLOGICAL ADJUVANT; INFLAMMASOME; INTERLEUKIN 1BETA; MULTIPROTEIN COMPLEX; OVALBUMIN; UNCLASSIFIED DRUG; ALUMINUM HYDROXIDE; ALUMINUM POTASSIUM SULFATE; AUTACOID; CARRIER PROTEIN; CIAS1 PROTEIN, MOUSE; IMMUNOLOGIC FACTOR; MAGNESIUM HYDROXIDE;

EID: 56149119563     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.181.6.3755     Document Type: Article
Times cited : (497)

References (28)
  • 1
    • 38649123396 scopus 로고    scopus 로고
    • The future of Toll-like receptor therapeutics
    • Parkinson, T. 2008. The future of Toll-like receptor therapeutics. Curr. Opin. Mol. Ther. 10: 21-31.
    • (2008) Curr. Opin. Mol. Ther. , vol.10 , pp. 21-31
    • Parkinson, T.1
  • 2
    • 33947304311 scopus 로고    scopus 로고
    • TLR9 agonists as adjuvants for prophylactic and therapeutic vaccines
    • Daubenberger, C. A. 2007. TLR9 agonists as adjuvants for prophylactic and therapeutic vaccines. Curr. Opin. Mol. Ther. 9: 45-52. (Pubitemid 46438448)
    • (2007) Current Opinion in Molecular Therapeutics , vol.9 , Issue.1 , pp. 45-52
    • Daubenberger, C.A.1
  • 3
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signalling
    • Akira, S., and K. Takeda. 2004. Toll-like receptor signalling. Nat. Rev. Immunol. 4: 499-511.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 4
    • 0034775153 scopus 로고    scopus 로고
    • Toll-like receptors control activation of adaptive immune responses
    • DOI 10.1038/ni712
    • Schnare, M., G. M. Barton, A. C. Holt, K. Takeda, S. Akira, and R. Medzhitov. 2001. Toll-like receptors control activation of adaptive immune responses. Nat. Immunol. 2: 947-950. (Pubitemid 32976167)
    • (2001) Nature Immunology , vol.2 , Issue.10 , pp. 947-950
    • Schnare, M.1    Barton, G.M.2    Holt, A.C.3    Takeda, K.4    Akira, S.5    Medzhitov, R.6
  • 5
    • 33845905223 scopus 로고    scopus 로고
    • Adjuvant-enhanced antibody responses in the absence of Toll-like receptor signaling
    • Gavin, A. L., K. Hoebe, B. Duong, T. Ota, C. Martin, B. Beutler, and D. Nemazee. 2006. Adjuvant-enhanced antibody responses in the absence of Toll-like receptor signaling. Science 314: 1936-1938.
    • (2006) Science , vol.314 , pp. 1936-1938
    • Gavin, A.L.1    Hoebe, K.2    Duong, B.3    Ota, T.4    Martin, C.5    Beutler, B.6    Nemazee, D.7
  • 6
    • 33845497181 scopus 로고    scopus 로고
    • Inflammatory caspases and inflammasomes: Master switches of inflammation
    • DOI 10.1038/sj.cdd.4402038, PII 4402038
    • Martinon, F., and J. Tschopp. 2007. Inflammatory caspases and inflammasomes: master switches of inflammation. Cell Death Differ. 14: 10-22. (Pubitemid 44911890)
    • (2007) Cell Death and Differentiation , vol.14 , Issue.1 , pp. 10-22
    • Martinon, F.1    Tschopp, J.2
  • 7
  • 8
    • 17644396670 scopus 로고    scopus 로고
    • CATERPILLER: A novel gene family important in immunity, cell death, and diseases
    • DOI 10.1146/annurev.immunol.23.021704.115616
    • Ting, J., and B. Davis. 2005. CATERPILLER: a novel gene family important in immunity, cell death, and diseases. Annu. Rev. Immunol. 23: 387-414. (Pubitemid 40563175)
    • (2005) Annual Review of Immunology , vol.23 , pp. 387-414
    • Ting, J.P.-Y.1    Davis, B.K.2
  • 9
    • 1642285783 scopus 로고    scopus 로고
    • NALP3 forms an IL-1β-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
    • DOI 10.1016/S1074-7613(04)00046-9, PII S1074761304000469
    • Agostini, L., F. Martinon, K. Burns, E. M. McDermott, P. N. Hawkins, and J. Tschopp. 2004. NALP3 forms an IL-1β processing inflammasome with increased activity in Muckle-Wells auto-inflammatory disorder. Immunity 20: 319-325. (Pubitemid 38388233)
    • (2004) Immunity , vol.20 , Issue.3 , pp. 319-325
    • Agostini, L.1    Martinon, F.2    Burns, K.3    McDermott, M.F.4    Hawkins, P.N.5    Tschopp, J.6
  • 11
    • 36849045915 scopus 로고    scopus 로고
    • The inflammasome: A danger sensing complex triggering innate immunity
    • DOI 10.1016/j.coi.2007.09.002, PII S0952791507001677, Autoimmunity / Allergy and Hypersenditivity
    • Petrilli, V., C. Dostert, D. A. Muruve, and J. Tschopp. 2007. The inflammasome: a danger sensing complex triggering innate immunity. Curr. Opin. Immunol. 19: 615-622. (Pubitemid 350236810)
    • (2007) Current Opinion in Immunology , vol.19 , Issue.6 , pp. 615-622
    • Petrilli, V.1    Dostert, C.2    Muruve, D.A.3    Tschopp, J.4
  • 12
    • 32944468985 scopus 로고    scopus 로고
    • Gout-associated uric acid crystals activate the NALP3 inflammasome
    • DOI 10.1038/nature04516, PII N04516
    • Martinon, F., V. Petrilli, A. Mayor, A. Tardivel, and J. Tschopp. 2006. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 440: 237-241. (Pubitemid 43372104)
    • (2006) Nature , vol.440 , Issue.7081 , pp. 237-241
    • Martinon, F.1    Petrilli, V.2    Mayor, A.3    Tardivel, A.4    Tschopp, J.5
  • 13
    • 43249125839 scopus 로고    scopus 로고
    • Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
    • DOI 10.1126/science.1156995
    • Dostert, C., V. Petrilli, R. Van Bruggen, C. Steele, B. T. Mossman, and J. Tschopp. 2008. Induction of innate immune responses through Nalp3 inflammasome sensing of asbestos and silica. Science 320: 674-677. (Pubitemid 351928351)
    • (2008) Science , vol.320 , Issue.5876 , pp. 674-677
    • Dostert, C.1    Petrilli, V.2    Van Bruggen, R.3    Steele, C.4    Mossman, B.T.5    Tschopp, J.6
  • 16
    • 45749111446 scopus 로고    scopus 로고
    • Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants
    • Eisenbarth, S. C., O. R. Colegio, W. O'Connor, F. S. Sutterwala, and R. A. Flavell. 2008. Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants. Nature 453: 1122-1126.
    • (2008) Nature , vol.453 , pp. 1122-1126
    • Eisenbarth, S.C.1    Colegio, O.R.2    O'Connor, W.3    Sutterwala, F.S.4    Flavell, R.A.5
  • 17
    • 34548027736 scopus 로고    scopus 로고
    • Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
    • DOI 10.1038/sj.cdd.4402195, PII 4402195
    • Petrilli, V., S. Papin, C. Dostert, A. Mayor, F. Martinon, and J. Tschopp. 2007. Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration. Cell Death Differ. 14: 1583-1589. (Pubitemid 47278844)
    • (2007) Cell Death and Differentiation , vol.14 , Issue.9 , pp. 1583-1589
    • Petrilli, V.1    Papin, S.2    Dostert, C.3    Mayor, A.4    Martinon, F.5    Tschopp, J.6
  • 21
    • 4243187214 scopus 로고    scopus 로고
    • Aluminium adjuvants-in retrospect and prospect
    • Lindblad, E. B. 2004. Aluminium adjuvants-in retrospect and prospect. Vaccine 22: 3658-3668.
    • (2004) Vaccine , vol.22 , pp. 3658-3668
    • Lindblad, E.B.1
  • 23
    • 0037435833 scopus 로고    scopus 로고
    • Analysis of the role of vaccine adjuvants in modulating dendritic cell activation and antigen presentation in vitro
    • DOI 10.1016/S0264-410X(02)00531-5, PII S0264410X02005315
    • Sun, H., K. G. Pollock, and J. M. Brewer. 2003. Analysis of the role of vaccine adjuvants in modulating dendritic cell activation and antigen presentation in vitro. Vaccine 21: 849-855. (Pubitemid 36131100)
    • (2003) Vaccine , vol.21 , Issue.9-10 , pp. 849-855
    • Sun, H.1    Pollock, K.G.J.2    Brewer, J.M.3
  • 24
    • 34247106805 scopus 로고    scopus 로고
    • Aluminum hydroxide adjuvants activate caspase-1 and induce IL-1β and IL-18 release
    • Li, H., S. Nookala, and F. Re. 2007. Aluminum hydroxide adjuvants activate caspase-1 and induce IL-1β and IL-18 release. J. Immunol. 178: 5271-5276.
    • (2007) J. Immunol. , vol.178 , pp. 5271-5276
    • Li, H.1    Nookala, S.2    Re, F.3
  • 25
    • 34248400446 scopus 로고    scopus 로고
    • + T cell differentiation by aluminum-containing adjuvants
    • + T cell differentiation by aluminum-containing adjuvants. Vaccine 25: 4575-4585.
    • (2007) Vaccine , vol.25 , pp. 4575-4585
    • Sokolovska, A.1    Hem, S.L.2    Hogenesch, H.3
  • 26
    • 47849087075 scopus 로고    scopus 로고
    • Cutting Edge: Inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3
    • Li, H., S. B. Willingham, J. P. Ting, and F. Re. 2008. Cutting Edge: Inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3. J. Immunol. 181: 17-21.
    • (2008) J. Immunol. , vol.181 , pp. 17-21
    • Li, H.1    Willingham, S.B.2    Ting, J.P.3    Re, F.4
  • 27
    • 0035869399 scopus 로고    scopus 로고
    • Functional caspase-1 is required for Langerhans cell migration and optimal contact sensitization in mice
    • Antonopoulos, C., M. Cumberbatch, R. J. Dearman, R. J. Daniel, I. Kimber, and R. W. Groves. 2001. Functional caspase-1 is required for Langerhans cell migration and optimal contact sensitization in mice. J. Immunol. 166: 3672-3677. (Pubitemid 32224888)
    • (2001) Journal of Immunology , vol.166 , Issue.6 , pp. 3672-3677
    • Antonopoulos, C.1    Cumberbatch, M.2    Dearman, R.J.3    Daniel, R.J.4    Kimber, I.5    Groves, R.W.6
  • 28
    • 0141998606 scopus 로고    scopus 로고
    • Molecular identification of a danger signal that alerts the immune system to dying cells
    • DOI 10.1038/nature01991
    • Shi, Y., J. E. Evans, and K. L. Rock. 2003. Molecular identification of a danger signal that alerts the immune system to dying cells. Nature 425: 516-521. (Pubitemid 37237047)
    • (2003) Nature , vol.425 , Issue.6957 , pp. 516-521
    • Shi, Y.1    Evans, J.E.2    Rock, K.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.