-
1
-
-
0142053206
-
The immunological and genetic basis of inflammatory bowel disease
-
Bouma, G. & Strober, W. The immunological and genetic basis of inflammatory bowel disease. Nature Rev. Immunol. 3, 521-533 (2003).
-
(2003)
Nature Rev. Immunol
, vol.3
, pp. 521-533
-
-
Bouma, G.1
Strober, W.2
-
2
-
-
30344445931
-
Inflammatory bowel disease: Epidemiology, pathogenesis, and therapeutic opportunities
-
Hanauer, S. B. Inflammatory bowel disease: epidemiology, pathogenesis, and therapeutic opportunities. Inflamm. Bowel Dis. 12 (suppl. 1), S3-S9 (2006).
-
(2006)
Inflamm. Bowel Dis
, vol.12
, Issue.SUPPL. 1
-
-
Hanauer, S.B.1
-
3
-
-
15544382565
-
Immunity, inflammation, and allergy in the gut
-
Macdonald, T. T. & Monteleone, G. Immunity, inflammation, and allergy in the gut. Science 307, 1920-1925 (2005).
-
(2005)
Science
, vol.307
, pp. 1920-1925
-
-
Macdonald, T.T.1
Monteleone, G.2
-
4
-
-
0036284984
-
The role of Th1/Th2 polarization in mucosal immunity
-
Neurath, M. F., Finotto, S. & Glimcher, L. H. The role of Th1/Th2 polarization in mucosal immunity. Nature Med. 8, 567-573 (2002).
-
(2002)
Nature Med
, vol.8
, pp. 567-573
-
-
Neurath, M.F.1
Finotto, S.2
Glimcher, L.H.3
-
5
-
-
17044385039
-
TLR signaling in the gut in health and disease
-
Abreu, M. T., Fukata, M. & Arditi, M. TLR signaling in the gut in health and disease. J. Immunol. 174, 4453-4460 (2005).
-
(2005)
J. Immunol
, vol.174
, pp. 4453-4460
-
-
Abreu, M.T.1
Fukata, M.2
Arditi, M.3
-
6
-
-
27144520307
-
Mechanisms of disease: Defensins in gastrointestinal diseases
-
Wehkamp, J., Fellermann, K., Herrlinger, K. R., Bevins, C. L. & Stange, E. F. Mechanisms of disease: defensins in gastrointestinal diseases. Nature Clin. Pract. Gastroenterol. Hepatol. 2, 406-415 (2005).
-
(2005)
Nature Clin. Pract. Gastroenterol. Hepatol
, vol.2
, pp. 406-415
-
-
Wehkamp, J.1
Fellermann, K.2
Herrlinger, K.R.3
Bevins, C.L.4
Stange, E.F.5
-
7
-
-
25844459154
-
NF-κB: Linking inflammation and immunity to cancer development and progression
-
Karin, M. & Greten, F. R. NF-κB: linking inflammation and immunity to cancer development and progression. Nature Rev. Immunol. 5, 749-759 (2005).
-
(2005)
Nature Rev. Immunol
, vol.5
, pp. 749-759
-
-
Karin, M.1
Greten, F.R.2
-
8
-
-
0036781052
-
NF-κB regulation in the immune system
-
Li, Q.&Verma, I. M. NF-κB regulation in the immune system. Nature Rev. Immunol. 2, 725-734 (2002).
-
(2002)
Nature Rev. Immunol
, vol.2
, pp. 725-734
-
-
Li, Q.1
Verma, I.M.2
-
9
-
-
0036234459
-
Missing pieces in the NF-κB puzzle
-
Ghosh, S. & Karin, M. Missing pieces in the NF-κB puzzle. Cell 109 (suppl.) S81-S96 (2002).
-
(2002)
Cell
, vol.109
, Issue.SUPPL.
-
-
Ghosh, S.1
Karin, M.2
-
10
-
-
0033638970
-
NEMO/IKKγ-deficient mice model incontinentia pigmenti
-
Schmidt-Supprian, M. et al. NEMO/IKKγ-deficient mice model incontinentia pigmenti. Mol. Cell 5, 981-992 (2000).
-
(2000)
Mol. Cell
, vol.5
, pp. 981-992
-
-
Schmidt-Supprian, M.1
-
11
-
-
0037031856
-
Cis elements of the villin gene control expression in restricted domains of the vertical (crypt) and horizontal (duodenum, cecum) axes of the intestine
-
Madison, B. B. et al. Cis elements of the villin gene control expression in restricted domains of the vertical (crypt) and horizontal (duodenum, cecum) axes of the intestine. J. Biol. Chem. 277, 33275-33283 (2002).
-
(2002)
J. Biol. Chem
, vol.277
, pp. 33275-33283
-
-
Madison, B.B.1
-
12
-
-
5644252874
-
TGF-β suppresses tumor progression in colon cancer by inhibition of IL-6 trans-signaling
-
Becker, C. et al. TGF-β suppresses tumor progression in colon cancer by inhibition of IL-6 trans-signaling. Immunity 21, 491-501 (2004).
-
(2004)
Immunity
, vol.21
, pp. 491-501
-
-
Becker, C.1
-
13
-
-
0034175632
-
Severe liver degeneration and lack of NF-κB activation in NEMO/IKKγ-deficient mice
-
Rudolph, D. et al. Severe liver degeneration and lack of NF-κB activation in NEMO/IKKγ-deficient mice. Genes Dev. 14, 854-862 (2000).
-
(2000)
Genes Dev
, vol.14
, pp. 854-862
-
-
Rudolph, D.1
-
14
-
-
0033634663
-
Female mice heterozygous for IKKγ/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti
-
Makris, C. et al. Female mice heterozygous for IKKγ/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti. Mol. Cell 5, 969-979 (2000).
-
(2000)
Mol. Cell
, vol.5
, pp. 969-979
-
-
Makris, C.1
-
15
-
-
33745343647
-
Positional specificity of defensin gene expression reveals Paneth cell heterogeneity in mouse small intestine
-
Darmoul, D. & Ouellette, A. J. Positional specificity of defensin gene expression reveals Paneth cell heterogeneity in mouse small intestine. Am. J. Physiol. 271, G68-G74 (1996).
-
(1996)
Am. J. Physiol
, vol.271
-
-
Darmoul, D.1
Ouellette, A.J.2
-
16
-
-
21044437368
-
Different cytokine response of primary colonic epithelial cells to commensal bacteria
-
Lan, J. G. et al. Different cytokine response of primary colonic epithelial cells to commensal bacteria. World J. Gastroenterol. 11, 3375-3384 (2005).
-
(2005)
World J. Gastroenterol
, vol.11
, pp. 3375-3384
-
-
Lan, J.G.1
-
17
-
-
33748558056
-
Achromosome 8 gene-cluster polymorphism with low human β-defensin 2 gene copy number predisposes to Crohn disease of the colon
-
Fellermann, K. et al. Achromosome 8 gene-cluster polymorphism with low human β-defensin 2 gene copy number predisposes to Crohn disease of the colon. Am. J. Hum. Genet. 79, 439-448 (2006).
-
(2006)
Am. J. Hum. Genet
, vol.79
, pp. 439-448
-
-
Fellermann, K.1
-
18
-
-
4043088499
-
IKKβ links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
-
Greten, F. R. et al. IKKβ links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell 118, 285-296 (2004).
-
(2004)
Cell
, vol.118
, pp. 285-296
-
-
Greten, F.R.1
-
19
-
-
0037142027
-
TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2
-
Pasparakis, M. et al. TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2. Nature 417, 861-866 (2002).
-
(2002)
Nature
, vol.417
, pp. 861-866
-
-
Pasparakis, M.1
-
20
-
-
0034661272
-
Complete lack of NF-κB activity in IKK1 and IKK2 double-deficient mice: Additional defect in neurulation
-
Li, Q., Estepa, G., Memet, S., Israel, A. & Verma, I. M. Complete lack of NF-κB activity in IKK1 and IKK2 double-deficient mice: additional defect in neurulation. Genes Dev. 14, 1729-1733 (2000).
-
(2000)
Genes Dev
, vol.14
, pp. 1729-1733
-
-
Li, Q.1
Estepa, G.2
Memet, S.3
Israel, A.4
Verma, I.M.5
-
21
-
-
34047189274
-
Normal epidermal differentiation but impaired skin barrier formation upon keratinocyte-restricted IKK1 ablation
-
doi:10.1038/ncb1560 in the press
-
Gareus, R. et al. Normal epidermal differentiation but impaired skin barrier formation upon keratinocyte-restricted IKK1 ablation. Nature Cell Biol. doi:10.1038/ncb1560 (in the press).
-
Nature Cell Biol
-
-
Gareus, R.1
-
23
-
-
0030954732
-
A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor α for Crohn's disease. Crohn's Disease cA2 Study Group
-
Targan, S. R. et al. A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor α for Crohn's disease. Crohn's Disease cA2 Study Group. N. Engl. J. Med. 337, 1029-1035 (1997).
-
(1997)
N. Engl. J. Med
, vol.337
, pp. 1029-1035
-
-
Targan, S.R.1
-
24
-
-
33846839443
-
Deletion of NEMO/IKKγ in liver parenchymal cells causes steatohepatitis and hepatocellular carcinoma
-
Luedde, T. et al. Deletion of NEMO/IKKγ in liver parenchymal cells causes steatohepatitis and hepatocellular carcinoma. Cancer Cell 11, 119-132 (2007).
-
(2007)
Cancer Cell
, vol.11
, pp. 119-132
-
-
Luedde, T.1
-
25
-
-
0029989339
-
Immune and inflammatory responses in TNFα-deficient mice: A critical requirement for TNFα in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response
-
Pasparakis, M., Alexopoulou, L., Episkopou, V. & Kollias, G. Immune and inflammatory responses in TNFα-deficient mice: a critical requirement for TNFα in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response. J. Exp. Med. 184, 1397-1411 (1996).
-
(1996)
J. Exp. Med
, vol.184
, pp. 1397-1411
-
-
Pasparakis, M.1
Alexopoulou, L.2
Episkopou, V.3
Kollias, G.4
-
26
-
-
0027297663
-
Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection
-
Pfeffer, K. et al. Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection. Cell 73, 457-467 (1993).
-
(1993)
Cell
, vol.73
, pp. 457-467
-
-
Pfeffer, K.1
-
27
-
-
0033166472
-
Unresponsiveness of MyD88-deficient mice to endotoxin
-
Kawai, T., Adachi, O., Ogawa, T., Takeda, K. & Akira, S. Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity 11, 115-122 (1999).
-
(1999)
Immunity
, vol.11
, pp. 115-122
-
-
Kawai, T.1
Adachi, O.2
Ogawa, T.3
Takeda, K.4
Akira, S.5
-
28
-
-
0141835046
-
Constitutive p40 promoter activation and IL-23 production in the terminal ileum mediated by dendritic cells
-
Becker, C. et al. Constitutive p40 promoter activation and IL-23 production in the terminal ileum mediated by dendritic cells. J. Clin. Invest. 112, 693-706 (2003).
-
(2003)
J. Clin. Invest
, vol.112
, pp. 693-706
-
-
Becker, C.1
-
29
-
-
21044456328
-
In vivo imaging of colitis and colon cancer development in mice using high resolution chromoendoscopy
-
Becker, C. et al. In vivo imaging of colitis and colon cancer development in mice using high resolution chromoendoscopy. Gut 54, 950-954 (2005).
-
(2005)
Gut
, vol.54
, pp. 950-954
-
-
Becker, C.1
|