TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo

Genes and Development

Volumn 19, Issue 22, 2005, Pages 2668-2681

  Shim, Jae Hyuck ^a   Xiao, Changchun ^a,f   Paschal, Amber E ^a   Bailey, Shannon T ^a   Rao, Ping ^a   Hayden, Matthew S ^a   Lee, Ki Young ^a   Bussey, Crystal ^a   Steckel, Michael ^a   Tanaka, Nobuyuki ^d   Yamada, Gen ^b   Akira, Shizuo ^e   Matsumoto, Kunihiro ^c   Ghosh, Sankar ^a,f  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b KUMAMOTO UNIVERSITY   (Japan)

^c NAGOYA UNIVERSITY   (Japan)

^d TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^e OSAKA UNIVERSITY   (Japan)

^f HARVARD MEDICAL SCHOOL   (United States)

Author keywords

JNK; NF B; TAB1; TAB2; TAK1; TGF

Indexed keywords

ADAPTOR PROTEIN; I KAPPA B ALPHA; I KAPPA B BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; LYMPHOTOXIN BETA; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN TAB1; PROTEIN TAB2; SMAD2 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TOLL LIKE RECEPTOR 3; TRANSCRIPTION FACTOR AP 1; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWNSTREAM PROCESSING; EMBRYO; EMBRYO CELL; EMBRYOTOXICITY; FEMALE; FIBROBLAST; GENE ACTIVATION; GENE CONTROL; GENE DELETION; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; LETHALITY; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FAMILY; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTIGENS, DIFFERENTIATION; APOPTOSIS; CELL LINE; CELL LINE, TRANSFORMED; CERCOPITHECUS AETHIOPS; COS CELLS; GTPASE-ACTIVATING PROTEINS; HUMANS; I-KAPPA B KINASE; INTERLEUKIN-1; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE KINASE KINASES; MICE; MUTATION; MYELOID DIFFERENTIATION FACTOR 88; NF-KAPPA B; PROTEIN KINASES; RECEPTORS, IMMUNOLOGIC; SIGNAL TRANSDUCTION; TNF RECEPTOR-ASSOCIATED FACTOR 2; TNF RECEPTOR-ASSOCIATED FACTOR 6; TOLL-LIKE RECEPTORS; TRANSCRIPTION FACTOR AP-1; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA;

EID: 27744577296     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.1360605     Document Type: Article

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