-
2
-
-
32944464648
-
Pathogen recognition and innate immunity
-
Akira, S., S. Uematsu, and O. Takeuchi, 2006. Pathogen recognition and innate immunity. Cell 124: 783-801.
-
(2006)
Cell
, vol.124
, pp. 783-801
-
-
Akira, S.1
Uematsu, S.2
Takeuchi, O.3
-
3
-
-
17644366913
-
NOD-LRR proteins: Role in host-microbial interactions and inflammatory disease
-
Inohara, Chamaillard, C. McDonald, and G. Nunez. 2005. NOD-LRR proteins: role in host-microbial interactions and inflammatory disease. Annu. Rev. Biochem. 74: 355-383.
-
(2005)
Annu. Rev. Biochem.
, vol.74
, pp. 355-383
-
-
Inohara1
Chamaillard2
McDonald, C.3
Nunez, G.4
-
4
-
-
33344476398
-
CATERPILLERs, pyrin and hereditary immunological disorders
-
Ting, J. P., D. L. Kastner, and H. M. Hoffman. 2006. CATERPILLERs, pyrin and hereditary immunological disorders. Nat. Rev. Immunol. 6: 183-195.
-
(2006)
Nat. Rev. Immunol.
, vol.6
, pp. 183-195
-
-
Ting, J.P.1
Kastner, D.L.2
Hoffman, H.M.3
-
5
-
-
32944479048
-
Host-microbe interactions: Shaping the evolution of the plant immune response
-
Chisholm, S. T., G. Coaker, B. Day, and B. J. Staskawicz. 2006. Host-microbe interactions: shaping the evolution of the plant immune response. Cell 124: 803-814.
-
(2006)
Cell
, vol.124
, pp. 803-814
-
-
Chisholm, S.T.1
Coaker, G.2
Day, B.3
Staskawicz, B.J.4
-
6
-
-
17944380130
-
CARD4/Nod1 mediates NF-κB and JNK activation by invasive Shigella flexneri
-
Girardin, S. E., R. Tournebize, M. Mavris, A. L. Page, X. Li, G. R. Stark, J. Bertin, P. S. DiStefano, M. Yaniv, P. J. Sansonetti, and D. J. Philpott. 2001. CARD4/Nod1 mediates NF-κB and JNK activation by invasive Shigella flexneri. EMBO Rep. 2: 736-742.
-
(2001)
EMBO Rep.
, vol.2
, pp. 736-742
-
-
Girardin, S.E.1
Tournebize, R.2
Mavris, M.3
Page, A.L.4
Li, X.5
Stark, G.R.6
Bertin, J.7
DiStefano, P.S.8
Yaniv, M.9
Sansonetti, P.J.10
Philpott, D.J.11
-
7
-
-
1342344961
-
Nod1 is an essential signal transducer in intestinal epithelial cells infected with bacteria that avoid recognition by Toll-like receptors
-
Kim, J. G., S. J. Lee, and M. F. Kagnoff. 2004. Nod1 is an essential signal transducer in intestinal epithelial cells infected with bacteria that avoid recognition by Toll-like receptors. Infect. Immun. 72: 1487-1495.
-
(2004)
Infect. Immun.
, vol.72
, pp. 1487-1495
-
-
Kim, J.G.1
Lee, S.J.2
Kagnoff, M.F.3
-
8
-
-
27744606975
-
Nod1 participates in the innate immune response to Pseudomonas aeruginosa
-
Travassos, L. H., L. A. Carneiro, S. E. Girardin, I. G. Boneca, R. Lemos, M. T. Bozza, R. C. Domingues, A. J. Coyle, J. Bertin, D. J. Philpott, and M. C. Plotkowski. 2005. Nod1 participates in the innate immune response to Pseudomonas aeruginosa. J. Biol. Chem. 280: 36714-36718.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 36714-36718
-
-
Travassos, L.H.1
Carneiro, L.A.2
Girardin, S.E.3
Boneca, I.G.4
Lemos, R.5
Bozza, M.T.6
Domingues, R.C.7
Coyle, A.J.8
Bertin, J.9
Philpott, D.J.10
Plotkowski, M.C.11
-
9
-
-
9244245293
-
Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island
-
Viala, I., C. Chaput, I. G. Boneca, A. Cardona, S. E. Girardin, A. P. Motan, R. Athman, S. Memet, M. R. Huerre, A. J. Coyle, et al. 2004. Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island. Nat. Immunol. 5: 1166-1174.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 1166-1174
-
-
Viala, I.1
Chaput, C.2
Boneca, I.G.3
Cardona, A.4
Girardin, S.E.5
Motan, A.P.6
Athman, R.7
Memet, S.8
Huerre, M.R.9
Coyle, A.J.10
-
10
-
-
33744965671
-
Nucleotide-binding oligomerization domain-1 and epidermal growth factor receptor: Critical regulators of β-defensins during Helicobacter pylori infection
-
Boughan, P. K., R. H. Argent, M. Body-Malapel, J. H. Park, K. E. Ewings, A. G. Bowie, S. J. Ong, S. J. Cook, O. E. Sorensen, B. A. Manzo, et al. 2006. Nucleotide-binding oligomerization domain-1 and epidermal growth factor receptor: critical regulators of β-defensins during Helicobacter pylori infection. J. Biol. Chem. 281: 11637-11648.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 11637-11648
-
-
Boughan, P.K.1
Argent, R.H.2
Body-Malapel, M.3
Park, J.H.4
Ewings, K.E.5
Bowie, A.G.6
Ong, S.J.7
Cook, S.J.8
Sorensen, O.E.9
Manzo, B.A.10
-
11
-
-
0038824980
-
An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid
-
Chamaillard, M., M. Hashimoto, Y. Horie, J. Masumoto, S. Qiu, L. Saab, Y. Ogura, A. Kawasaki, K. Fukase, S. Kusumoto, et al. 2003. An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid. Nat. Immunol. 4: 702-707.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 702-707
-
-
Chamaillard, M.1
Hashimoto, M.2
Horie, Y.3
Masumoto, J.4
Qiu, S.5
Saab, L.6
Ogura, Y.7
Kawasaki, A.8
Fukase, K.9
Kusumoto, S.10
-
12
-
-
20144382924
-
Peptidoglycan signaling in innate immunity and inflammatory disease
-
McDonald, C., N. Inohara, and G. Nunez. 2005. Peptidoglycan signaling in innate immunity and inflammatory disease. J. Biol. Chem. 280: 20177-20180.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 20177-20180
-
-
McDonald, C.1
Inohara, N.2
Nunez, G.3
-
13
-
-
0038615855
-
Nod1 detects a unique muropeptide from Gram-negative bacterial peptidoglycan
-
Girardin, S. E., I. G. Boneca, L. A. Carneiro, A. Antignac, M. Jehanno, J. Viala, K. Tedin, M. K. Taha, A. Labigne, U. Zahringer, et al. 2003. Nod1 detects a unique muropeptide from Gram-negative bacterial peptidoglycan. Science 300: 1584-1587.
-
(2003)
Science
, vol.300
, pp. 1584-1587
-
-
Girardin, S.E.1
Boneca, I.G.2
Carneiro, L.A.3
Antignac, A.4
Jehanno, M.5
Viala, J.6
Tedin, K.7
Taha, M.K.8
Labigne, A.9
Zahringer, U.10
-
14
-
-
3142654767
-
Differential activation of the inflammasome bycaspase-1 adaptors ASC and Ipaf
-
Mariathasan, S., K. Newton, D. M. Monack, D. Vucic, D. M. French, W. P. Lee, M. Roose-Girma, S. Erickson, and V. M. Dixit. 2004. Differential activation of the inflammasome bycaspase-1 adaptors ASC and Ipaf. Nature 430: 213-218.
-
(2004)
Nature
, vol.430
, pp. 213-218
-
-
Mariathasan, S.1
Newton, K.2
Monack, D.M.3
Vucic, D.4
French, D.M.5
Lee, W.P.6
Roose-Girma, M.7
Erickson, S.8
Dixit, V.M.9
-
15
-
-
33645770203
-
The Bircle cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection
-
Zamboni, D. S., K. S. Kobayashi, T. Kohlsdorf, Y. Ogura, E. M. Long, R. E. Vance, K. Kuida, S. Mariathasan, V. M. Dixit, R. A. Flavell, W. F. Dietrich, and C. R. Roy. 2006. The Bircle cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection. Nat. Immunol. 7:318-325.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 318-325
-
-
Zamboni, D.S.1
Kobayashi, K.S.2
Kohlsdorf, T.3
Ogura, Y.4
Long, E.M.5
Vance, R.E.6
Kuida, K.7
Mariathasan, S.8
Dixit, V.M.9
Flavell, R.A.10
Dietrich, W.F.11
Roy, C.R.12
-
16
-
-
33744493091
-
Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1β via Ipaf
-
Miao, E. A., C. M. Alpuche-Aranda, M. Dors, A. E. Clark, M. W. Bader, S. I. Miller, and A. Aderem. 2006. Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1β via Ipaf. Nat. Immunol. 7: 576-582.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 576-582
-
-
Miao, E.A.1
Alpuche-Aranda, C.M.2
Dors, M.3
Clark, A.E.4
Bader, M.W.5
Miller, S.I.6
Aderem, A.7
-
17
-
-
33744464740
-
Cytosolic flagellin requires Ipaf for activation of caspase-1 and interieukin 1β in salmonella-infected macrophages
-
Franchi, L, A. Amer, M. Body-Malapei, T. D. Kanneganti, N. Ozoren, R. Jagirdar, N. Inohara, P. Vandenabeele, J. Bertin, A. Coyle, E. P. Grant, and G. Nunez. 2006. Cytosolic flagellin requires Ipaf for activation of caspase-1 and interieukin 1β in salmonella-infected macrophages. Nat. Immunol. 7: 569-575.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 569-575
-
-
Franchi, L.1
Amer, A.2
Body-Malapei, M.3
Kanneganti, T.D.4
Ozoren, N.5
Jagirdar, R.6
Inohara, N.7
Vandenabeele, P.8
Bertin, J.9
Coyle, A.10
Grant, E.P.11
Nunez, G.12
-
18
-
-
32944468985
-
Gout-associated uric acid crystals activate the NALP3 inflammasome
-
Martinon, F., V. Petrilli, A. Mayor, A. Tardivel, and J. Tschopp. 2006. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 440: 237-241.
-
(2006)
Nature
, vol.440
, pp. 237-241
-
-
Martinon, F.1
Petrilli, V.2
Mayor, A.3
Tardivel, A.4
Tschopp, J.5
-
19
-
-
32944462834
-
Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3
-
Kanneganti, T. D., N. Ozoren, M. Body-Malapel, A. Amer, J. H. Park, L. Franchi, J. Whitfieid, W. Barchet, M. Colonna, P. Vandenabeele, et al. 2006. Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3. Nature 440: 233-236.
-
(2006)
Nature
, vol.440
, pp. 233-236
-
-
Kanneganti, T.D.1
Ozoren, N.2
Body-Malapel, M.3
Amer, A.4
Park, J.H.5
Franchi, L.6
Whitfieid, J.7
Barchet, W.8
Colonna, M.9
Vandenabeele, P.10
-
20
-
-
33644985564
-
Critical role for NALP3/CLAS1/Cryopyrin in innate and adaptive immuniry through its regulation of caspase-1
-
Sutterwala, F. S., Y. Ogura, M. Szczepanik, M. Lara-Tejero, G. S. Lichtenberger, E. P. Grant, J. Bertin, A. J. Coyle, J. E. Galan, P. W. Askenase, and R. A. Flavell. 2006. Critical role for NALP3/CLAS1/Cryopyrin in innate and adaptive immuniry through its regulation of caspase-1. Immunity 24: 317-327.
-
(2006)
Immunity
, vol.24
, pp. 317-327
-
-
Sutterwala, F.S.1
Ogura, Y.2
Szczepanik, M.3
Lara-Tejero, M.4
Lichtenberger, G.S.5
Grant, E.P.6
Bertin, J.7
Coyle, A.J.8
Galan, J.E.9
Askenase, P.W.10
Flavell, R.A.11
-
21
-
-
32944470765
-
Cryopyrin activates the inflammasome in response to toxins and ATP
-
Mariarhasan, S., D. S. Weiss, K. Newton, J. McBride, K. O'Rourke, M. Roose-Girma, W. P. Lee, Y. Weinrauch, D. M. Monack, and V. M. Dixit. 2006. Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 440: 228-232.
-
(2006)
Nature
, vol.440
, pp. 228-232
-
-
Mariarhasan, S.1
Weiss, D.S.2
Newton, K.3
McBride, J.4
O'Rourke, K.5
Roose-Girma, M.6
Lee, W.P.7
Weinrauch, Y.8
Monack, D.M.9
Dixit, V.M.10
-
22
-
-
31744441475
-
Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin
-
Boyden, E. D., and W. F. Dietrich. 2006. Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin. Nat. Genet. 38: 240-244.
-
(2006)
Nat. Genet.
, vol.38
, pp. 240-244
-
-
Boyden, E.D.1
Dietrich, W.F.2
-
23
-
-
0037228017
-
Bircle is the gene within the Lgn1 locus associated with resistance to Legionella pneumophila
-
Diei, E., S. H. Lee, S. Gauthier, Z. Yaraghi, M. Tremblay, S. Vidal, and P. Gros. 2003. Bircle is the gene within the Lgn1 locus associated with resistance to Legionella pneumophila. Nat. Genet. 33: 55-60.
-
(2003)
Nat. Genet.
, vol.33
, pp. 55-60
-
-
Diei, E.1
Lee, S.H.2
Gauthier, S.3
Yaraghi, Z.4
Tremblay, M.5
Vidal, S.6
Gros, P.7
-
24
-
-
0037458665
-
Host recognition of bacterial muramyl dipeptide mediated through NOD2: Implications for Crohn's disease
-
Inohara, N., Y. Ogura, A. Fontalba, O. Gutierrez, F. Pons, J. Crespo, K. Fukase, S. Inamura, S. Kusumoto, M. Hashimoto, S. J. Foster, A. P. Moran, J. L. Fernandez-Luna, and G. Nunez. 2003. Host recognition of bacterial muramyl dipeptide mediated through NOD2: implications for Crohn's disease. J. Biol. Chem. 278: 5509-5512.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 5509-5512
-
-
Inohara, N.1
Ogura, Y.2
Fontalba, A.3
Gutierrez, O.4
Pons, F.5
Crespo, J.6
Fukase, K.7
Inamura, S.8
Kusumoto, S.9
Hashimoto, M.10
Foster, S.J.11
Moran, A.P.12
Fernandez-Luna, J.L.13
Nunez, G.14
-
25
-
-
2342583513
-
Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition
-
Tanabe, T., M. Chamaillard, Y. Ogura, L. Zhu, S. Qiu, J. Masumoto, P. Ghosh, A. Moran, M. M. Predergast, G. Tromp, C. J. Williams, N. Inohara, and G. Nunez. 2004. Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition. EMBO J. 23: 1587-1597.
-
(2004)
EMBO J.
, vol.23
, pp. 1587-1597
-
-
Tanabe, T.1
Chamaillard, M.2
Ogura, Y.3
Zhu, L.4
Qiu, S.5
Masumoto, J.6
Ghosh, P.7
Moran, A.8
Predergast, M.M.9
Tromp, G.10
Williams, C.J.11
Inohara, N.12
Nunez, G.13
-
26
-
-
0035951792
-
Human Nod1 confers responsive ness to bacterial lipopolysaccharides
-
Inohara, N., Y. Ogura, F. F. Chen, A. Muto, and G. Nunez. 2001. Human Nod1 confers responsive ness to bacterial lipopolysaccharides. J. Biol. Chem. 276: 2551-2554.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 2551-2554
-
-
Inohara, N.1
Ogura, Y.2
Chen, F.F.3
Muto, A.4
Nunez, G.5
-
27
-
-
33646024628
-
The apoptosome activates caspase-9 by dimerization
-
Pop, C. J. Timmer, S. Sperandio, and G. S. Salvesen. 2006. The apoptosome activates caspase-9 by dimerization. Mol. Cell 22: 269-275.
-
(2006)
Mol. Cell
, vol.22
, pp. 269-275
-
-
Pop1
Timmer, C.J.2
Sperandio, S.3
Salvesen, G.S.4
-
28
-
-
0037075551
-
RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems
-
Kobayashi, K., N. Inohara, L. D. Hernandez, J. E. Galan, G. Nunez, C. A. Janeway, R. Medzhitov, and R. A. Flavell. 2002. RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems. Nature 416: 194-199.
-
(2002)
Nature
, vol.416
, pp. 194-199
-
-
Kobayashi, K.1
Inohara, N.2
Hernandez, L.D.3
Galan, J.E.4
Nunez, G.5
Janeway, C.A.6
Medzhitov, R.7
Flavell, R.A.8
-
29
-
-
0034623225
-
An induced proximity model for NF-κB activation in the Nod1/RICK and RIP signaling pathways
-
Inohara, N., T. Koseki, J. Lin, L. del Peso, P. C. Lucas, F. F. Chen, Y. Ogura, and G. Nunez. 2000. An induced proximity model for NF-κB activation in the Nod1/RICK and RIP signaling pathways. J. Biol. Chem. 275: 27823-27831.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 27823-27831
-
-
Inohara, N.1
Koseki, T.2
Lin, J.3
Del Peso, L.4
Lucas, P.C.5
Chen, F.F.6
Ogura, Y.7
Nunez, G.8
-
30
-
-
11144289688
-
The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO
-
Abbott, D. W., A. Wilkins, J. M. Asara, and L. C. Cantley. 2004. The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO. Curr. Biol. 14: 2217-2227.
-
(2004)
Curr. Biol.
, vol.14
, pp. 2217-2227
-
-
Abbott, D.W.1
Wilkins, A.2
Asara, J.M.3
Cantley, L.C.4
-
31
-
-
4444376712
-
Signaling to NF-κB
-
Hayden, M. S., and S. Ghosh. 2004. Signaling to NF-κB. Genes Dev. 18: 2195-2224.
-
(2004)
Genes Dev.
, vol.18
, pp. 2195-2224
-
-
Hayden, M.S.1
Ghosh, S.2
-
32
-
-
13244292161
-
Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract
-
Kobayashi, K. S., M. Chamaillard, Y. Ogura, O. Henegariu, N. Inohara, G. Nunez, and R. A. Flavell. 2005. Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract. Science 307: 731-734.
-
(2005)
Science
, vol.307
, pp. 731-734
-
-
Kobayashi, K.S.1
Chamaillard, M.2
Ogura, Y.3
Henegariu, O.4
Inohara, N.5
Nunez, G.6
Flavell, R.A.7
-
33
-
-
0037290856
-
New insights into the mechanism of IL-1β maturation
-
Burns, K., F. Martinon, and J. Tschopp. 2003. New insights into the mechanism of IL-1β maturation. Curr. Opin. Immunol. 15: 26-30.
-
(2003)
Curr. Opin. Immunol.
, vol.15
, pp. 26-30
-
-
Burns, K.1
Martinon, F.2
Tschopp, J.3
-
35
-
-
33646017449
-
Distinct roles of TLR2 and the adaptor ASC in IL-1β/IL-18 secretion in response to Listeria monocytogenes
-
Ozoren, N., J. Masumoto, L. Franchi, T. D. Kanneganti, M. Body-Malapel, I. Erturk, R. Jagirdar, L. Zhu, N. Inohara, J. Benin, A. Coyle, E. P. Grant, and G. Nunez. 2006. Distinct roles of TLR2 and the adaptor ASC in IL-1β/IL-18 secretion in response to Listeria monocytogenes. J. Immunol. 176: 4337-4342.
-
(2006)
J. Immunol.
, vol.176
, pp. 4337-4342
-
-
Ozoren, N.1
Masumoto, J.2
Franchi, L.3
Kanneganti, T.D.4
Body-Malapel, M.5
Erturk, I.6
Jagirdar, R.7
Zhu, L.8
Inohara, N.9
Benin, J.10
Coyle, A.11
Grant, E.P.12
Nunez, G.13
-
36
-
-
26844452231
-
Innate immunity against Francisella tularensis is dependent on the ASC/caspase-1 axis
-
Mariathasan, S., D. S. Weiss, V. M. Dixit, and D. M. Monack. 2005. Innate immunity against Francisella tularensis is dependent on the ASC/caspase-1 axis. J. Exp. Med. 202: 1043-1049.
-
(2005)
J. Exp. Med.
, vol.202
, pp. 1043-1049
-
-
Mariathasan, S.1
Weiss, D.S.2
Dixit, V.M.3
Monack, D.M.4
-
37
-
-
31944437924
-
Nod1 acts as an intracellular receptor to stimulate chemokine production and neutrophil recruitment in vivo
-
Masumoto, J., K. Yang, S. Varambally, M. Hasegawa, S. A. Tomlins, S. Qiu, Y. Fujimoto, A. Kawasaki, S. J. Foster, Y. Horie, et al. 2006. Nod1 acts as an intracellular receptor to stimulate chemokine production and neutrophil recruitment in vivo. J. Exp. Med. 203: 203-213.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 203-213
-
-
Masumoto, J.1
Yang, K.2
Varambally, S.3
Hasegawa, M.4
Tomlins, S.A.5
Qiu, S.6
Fujimoto, Y.7
Kawasaki, A.8
Foster, S.J.9
Horie, Y.10
-
38
-
-
0034252293
-
Secretion of microbicidal α-defensins by intestinal Paneth cells in response to bacteria
-
Ayabe, T., D. P. Satchell, C. L. Wilson, W. C. Parks, M. E. Selsted, and A. J. Ouellette. 2000. Secretion of microbicidal α-defensins by intestinal Paneth cells in response to bacteria. Nat. Immunol. 1: 113-118.
-
(2000)
Nat. Immunol.
, vol.1
, pp. 113-118
-
-
Ayabe, T.1
Satchell, D.P.2
Wilson, C.L.3
Parks, W.C.4
Selsted, M.E.5
Ouellette, A.J.6
-
39
-
-
10744222688
-
Expression of NOD2 in Paneth cells: A possible link to Crohn's ileitis
-
Ogura, Y., S. Lala, W. Xin, E. Smith, T. A. Dowds, F. F. Chen, E. Zimmermann, M. Tretiakova, J. H. Cho, J. Hart, et al. 2003. Expression of NOD2 in Paneth cells: a possible link to Crohn's ileitis. Gut 52: 1591-1597.
-
(2003)
Gut
, vol.52
, pp. 1591-1597
-
-
Ogura, Y.1
Lala, S.2
Xin, W.3
Smith, E.4
Dowds, T.A.5
Chen, F.F.6
Zimmermann, E.7
Tretiakova, M.8
Cho, J.H.9
Hart, J.10
-
40
-
-
33644849605
-
NOD2/CARD15 mediates induction of the antimicrobial peptide human β-defensin-2
-
Voss, E., J. Wehkamp, K. Wehkamp, E. F. Stange, J. M. Schroder, and J. Harder. 2006. NOD2/CARD15 mediates induction of the antimicrobial peptide human β-defensin-2. J. Biol. Chem. 281: 2005-2011.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 2005-2011
-
-
Voss, E.1
Wehkamp, J.2
Wehkamp, K.3
Stange, E.F.4
Schroder, J.M.5
Harder, J.6
-
41
-
-
0038824980
-
An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid
-
Chamaillard, M., M. Hashimoto, Y. Horie, J. Masumoto, Q. Su, L. Saab, Y. Ogura, A. Kawasaki, K. Fukase, S. Kusumoto, et al. 2003. An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid. Nat. Immunol. 4: 702-707.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 702-707
-
-
Chamaillard, M.1
Hashimoto, M.2
Horie, Y.3
Masumoto, J.4
Su, Q.5
Saab, L.6
Ogura, Y.7
Kawasaki, A.8
Fukase, K.9
Kusumoto, S.10
-
42
-
-
28444471235
-
Synergistic effect of Nod1 and Nod2 agonists with Toll-like receptor agonists on human dendritic cells to generate interleukin-12 and T helper type 1 cells
-
Tada, H., S. Aiba, K. Shibata, T. Ohteki, and H. Takada. 2005. Synergistic effect of Nod1 and Nod2 agonists with Toll-like receptor agonists on human dendritic cells to generate interleukin-12 and T helper type 1 cells. Infect. Immun. 73: 7967-7976.
-
(2005)
Infect. Immun.
, vol.73
, pp. 7967-7976
-
-
Tada, H.1
Aiba, S.2
Shibata, K.3
Ohteki, T.4
Takada, H.5
-
43
-
-
23844521000
-
Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists
-
Fritz, J. H., S. E. Girardin, C. Fitting, C. Werts, D. Mengin-Lecreulx, M. Caroff, J. M. Cavaillon, D. J. Philpott, and M. Adib-Conquy. 2005. Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists. Eur. J. Immunol. 35: 2459-2470.
-
(2005)
Eur. J. Immunol.
, vol.35
, pp. 2459-2470
-
-
Fritz, J.H.1
Girardin, S.E.2
Fitting, C.3
Werts, C.4
Mengin-Lecreulx, D.5
Caroff, M.6
Cavaillon, J.M.7
Philpott, D.J.8
Adib-Conquy, M.9
-
44
-
-
0036828844
-
Induction of Nod2 in myelomonocytic and intestinal epithelial cells via nuclear factor-κB activation
-
Gutierrez, O., C. Pipaon, N. Inohara, A. Fontalba, Y. Ogura, F. Prosper, G. Nunez, and J. L. Fernandez-Luna. 2002. Induction of Nod2 in myelomonocytic and intestinal epithelial cells via nuclear factor-κB activation. J. Biol. Chem. 277: 41701-41705.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 41701-41705
-
-
Gutierrez, O.1
Pipaon, C.2
Inohara, N.3
Fontalba, A.4
Ogura, Y.5
Prosper, F.6
Nunez, G.7
Fernandez-Luna, J.L.8
-
45
-
-
0035078190
-
Synergistic effect of muramyldipeptide with lipopolysaccharide or lipoteichoic acid to induce inflammatory cytokines in human monocytic cells in culture
-
Yang, S., R. Tamai, S. Akashi, O. Takeuchi, S. Akira, S. Sugawara, and H. Takada. 2001. Synergistic effect of muramyldipeptide with lipopolysaccharide or lipoteichoic acid to induce inflammatory cytokines in human monocytic cells in culture. Infect. Immun. 69: 2045-2053.
-
(2001)
Infect. Immun.
, vol.69
, pp. 2045-2053
-
-
Yang, S.1
Tamai, R.2
Akashi, S.3
Takeuchi, O.4
Akira, S.5
Sugawara, S.6
Takada, H.7
-
46
-
-
7944231451
-
ASC is essential for LPS-induced activation of procaspase-1 independently of TLR-associated signal adaptor molecules
-
Yamamoto, M., K. Yaginuma, H. Tsutsui, J. Sagara, X. Guan, E. Seki, K. Yasuda, S. Akira, K. Nakanishi, T. Noda, and S. Taniguchi. 2004. ASC is essential for LPS-induced activation of procaspase-1 independently of TLR-associated signal adaptor molecules. Genes Cells 9: 1055-1067.
-
(2004)
Genes Cells
, vol.9
, pp. 1055-1067
-
-
Yamamoto, M.1
Yaginuma, K.2
Tsutsui, H.3
Sagara, J.4
Guan, X.5
Seki, E.6
Yasuda, K.7
Akira, S.8
Nakanishi, K.9
Noda, T.10
Taniguchi, S.11
-
47
-
-
1542343954
-
Shielding the double-edged sword: Negative regulation of the innate immune system
-
Kobayashi, K. S., and R. A. Flavell. 2004. Shielding the double-edged sword: negative regulation of the innate immune system. J. Leukocyte Biol. 75: 428-433.
-
(2004)
J. Leukocyte Biol.
, vol.75
, pp. 428-433
-
-
Kobayashi, K.S.1
Flavell, R.A.2
-
48
-
-
0035064073
-
The bare lymphocyte syndrome and the regulation of MHC expression
-
Reith, W., and B. Mach. 2001. The bare lymphocyte syndrome and the regulation of MHC expression. Annu. Rev. Immunol. 19: 331-373.
-
(2001)
Annu. Rev. Immunol.
, vol.19
, pp. 331-373
-
-
Reith, W.1
Mach, B.2
-
49
-
-
0035978651
-
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
-
Hugot, J. P., M. Chamaillard, H. Zouali, S. Lesage, J. P. Cezard, J. Belaiche, S. Aimer, C. Tysk, C. A. O'Morain, M. Gassull, et al. 2001. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 411: 599-603.
-
(2001)
Nature
, vol.411
, pp. 599-603
-
-
Hugot, J.P.1
Chamaillard, M.2
Zouali, H.3
Lesage, S.4
Cezard, J.P.5
Belaiche, J.6
Aimer, S.7
Tysk, C.8
O'Morain, C.A.9
Gassull, M.10
-
50
-
-
0035978533
-
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
-
Ogura, Y., D. K. Bonen, N. Inohara, D. L. Nicolae, F. F. Chen, R. Ramos, H. Britton, T. Moran, R. Karaliuskas, R. H. Duerr, et al. 2001. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 411: 603-606.
-
(2001)
Nature
, vol.411
, pp. 603-606
-
-
Ogura, Y.1
Bonen, D.K.2
Inohara, N.3
Nicolae, D.L.4
Chen, F.F.5
Ramos, R.6
Britton, H.7
Moran, T.8
Karaliuskas, R.9
Duerr, R.H.10
-
51
-
-
21144468350
-
Muramyl dipeptide and Toll-like receptor sensitivity in NOD2-associated Crohn's disease
-
van Heel, D. A., S. Ghosh, M. Butler, K. A. Hunt, A. M. Lundberg, T. Ahmad, D. P. McGovern, C. Onnie, K. Negoro, S. Goldthorpe, et al. 2005. Muramyl dipeptide and Toll-like receptor sensitivity in NOD2-associated Crohn's disease. Lancet 365: 1794-1796.
-
(2005)
Lancet
, vol.365
, pp. 1794-1796
-
-
Van Heel, D.A.1
Ghosh, S.2
Butler, M.3
Hunt, K.A.4
Lundberg, A.M.5
Ahmad, T.6
McGovern, D.P.7
Onnie, C.8
Negoro, K.9
Goldthorpe, S.10
-
52
-
-
11144279151
-
Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: A metaanalysis
-
Economou, M., T. A. Trikalinos, K. T. Loizou, E. V. Tsianos, and J. P. Ioannidis. 2004. Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: a metaanalysis. Am. J. Gastroenterol. 99: 2393-2404.
-
(2004)
Am. J. Gastroenterol.
, vol.99
, pp. 2393-2404
-
-
Economou, M.1
Trikalinos, T.A.2
Loizou, K.T.3
Tsianos, E.V.4
Ioannidis, J.P.5
-
53
-
-
13244277880
-
Nod2 mutation in Crohn's disease potentiates NF-κB activity and IL-1β processing
-
Maeda, S., L. C. Hsu, H. Liu, L. A. Bankston, M. Iimura, M. F. Kagnoff, L. Eckmann, and M. Karin. 2005. Nod2 mutation in Crohn's disease potentiates NF-κB activity and IL-1β processing. Science 307: 734-738.
-
(2005)
Science
, vol.307
, pp. 734-738
-
-
Maeda, S.1
Hsu, L.C.2
Liu, H.3
Bankston, L.A.4
Iimura, M.5
Kagnoff, M.F.6
Eckmann, L.7
Karin, M.8
-
54
-
-
4444253690
-
NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses
-
Watanabe, T., A. Kitani, P. J. Murray, and W. Sttobet. 2004. NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses. Nat. Immunol. 5: 800-808.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 800-808
-
-
Watanabe, T.1
Kitani, A.2
Murray, P.J.3
Sttobet, W.4
-
55
-
-
7244257312
-
NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal α-defensin expression
-
Wehkamp, J., J. Harder, M. Weichenthal, M. Schwab, E. Schaffeler, M. Schlee, K. R. Herrlinger, A. Stallmach, F. Noack, P. Fritz, et al. 2004. NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal α-defensin expression. Gut 53: 1658-1664.
-
(2004)
Gut
, vol.53
, pp. 1658-1664
-
-
Wehkamp, J.1
Harder, J.2
Weichenthal, M.3
Schwab, M.4
Schaffeler, E.5
Schlee, M.6
Herrlinger, K.R.7
Stallmach, A.8
Noack, F.9
Fritz, P.10
-
56
-
-
33644859324
-
Mutations in innate immune system NOD2/CARD 15 and TLR-4 (Thr399Ilc) genes influence the risk for severe acute graft-versus-host disease in patients who underwent an allogeneic transplantation
-
Elmaagacli, A. H., M. Koldehoff, H. Hindahl, N. K. Steckel, R. Trenschel, R. Peceny, H. Ottinger, P. M. Rath, R. S. Ross, M. Roggendorf, et al. 2006. Mutations in innate immune system NOD2/CARD 15 and TLR-4 (Thr399Ilc) genes influence the risk for severe acute graft-versus-host disease in patients who underwent an allogeneic transplantation. Transplantation 81: 247-254.
-
(2006)
Transplantation
, vol.81
, pp. 247-254
-
-
Elmaagacli, A.H.1
Koldehoff, M.2
Hindahl, H.3
Steckel, N.K.4
Trenschel, R.5
Peceny, R.6
Ottinger, H.7
Rath, P.M.8
Ross, R.S.9
Roggendorf, M.10
-
57
-
-
33646591889
-
Prognostic significance of NOD2/CARD15 variants in HLA-identical sibling hematopoietic stem cell transplantation: Effect on long-term outcome is confirmed in 2 independent cohorts and may be modulated by the type of gastrointestinal decontamination
-
Holler, E., G. Rogler, J. Brenmoehl, J. Hahn, H. Hetfarth, H. Greinix, A. M. Dickinson, G. Socie, D. Wolff, G. Fischer, et al. 2006. Prognostic significance of NOD2/CARD15 variants in HLA-identical sibling hematopoietic stem cell transplantation: effect on long-term outcome is confirmed in 2 independent cohorts and may be modulated by the type of gastrointestinal decontamination. Blood 107: 4189-4193.
-
(2006)
Blood
, vol.107
, pp. 4189-4193
-
-
Holler, E.1
Rogler, G.2
Brenmoehl, J.3
Hahn, J.4
Hetfarth, H.5
Greinix, H.6
Dickinson, A.M.7
Socie, G.8
Wolff, D.9
Fischer, G.10
-
58
-
-
17944372335
-
CARD15 mutations in Blau syndrome
-
Miceli-Richard, C., S. Lesage, M. Rybojad, A. M. Prieur, S. Manouvrier- Hanu, R. Hafner, M. Chamaillard, H. Zouali, G. Thomas, and J. P. Hugot. 2001. CARD15 mutations in Blau syndrome. Nat Genet. 29: 19-20.
-
(2001)
Nat Genet.
, vol.29
, pp. 19-20
-
-
Miceli-Richard, C.1
Lesage, S.2
Rybojad, M.3
Prieur, A.M.4
Manouvrier- Hanu, S.5
Hafner, R.6
Chamaillard, M.7
Zouali, H.8
Thomas, G.9
Hugot, J.P.10
-
59
-
-
19944431022
-
Early-onser sarcoidosis and CARD15 mutations with constitutive nuclear factor-κB activation: Common genetic etiology with Blau syndrome
-
Kanazawa, N., I. Okafuji, N. Kambe, R. Nishikomori, M. Nakata-Hizume, S. Nagai, A. Fuji, T. Yuasa, A. Manki, Y. Sakurai, et al. 2005. Early-onser sarcoidosis and CARD15 mutations with constitutive nuclear factor-κB activation: common genetic etiology with Blau syndrome. Blood 105: 1195-1197.
-
(2005)
Blood
, vol.105
, pp. 1195-1197
-
-
Kanazawa, N.1
Okafuji, I.2
Kambe, N.3
Nishikomori, R.4
Nakata-Hizume, M.5
Nagai, S.6
Fuji, A.7
Yuasa, T.8
Manki, A.9
Sakurai, Y.10
-
60
-
-
20244364812
-
NOD1 variation, immunoglobulin e and asthma
-
Hysi, P., M. Kabesch, M. F. Moffatt, M. Schedel, D. Carr, Y. Zhang, B. Boardman, E. von Mutius, S. K. Weiland, W. Leupold, et al. 2005. NOD1 variation, immunoglobulin E and asthma. Hum. Mol. Genet. 14: 935-941.
-
(2005)
Hum. Mol. Genet.
, vol.14
, pp. 935-941
-
-
Hysi, P.1
Kabesch, M.2
Moffatt, M.F.3
Schedel, M.4
Carr, D.5
Zhang, Y.6
Boardman, B.7
Von Mutius, E.8
Weiland, S.K.9
Leupold, W.10
-
61
-
-
21344448610
-
Association of NOD1 polymorphisms with atopic eczema and related phenorypes
-
Weidinger, S., N. Klopp, L. Rummler, S. Wagenpfeil, N. Novak, H. J. Baurecht, W. Groer, U. Darsow, J. Heinrich, A. Gauger, et al. 2005. Association of NOD1 polymorphisms with atopic eczema and related phenorypes. J Allergy Clin. Immunol. 116: 177-184.
-
(2005)
J Allergy Clin. Immunol.
, vol.116
, pp. 177-184
-
-
Weidinger, S.1
Klopp, N.2
Rummler, L.3
Wagenpfeil, S.4
Novak, N.5
Baurecht, H.J.6
Groer, W.7
Darsow, U.8
Heinrich, J.9
Gauger, A.10
-
62
-
-
0036196657
-
Interactions between respiratory tract infections and atopy in the aetiology of asthma
-
Holt, P. G., and P. D. Sly. 2002. Interactions between respiratory tract infections and atopy in the aetiology of asthma. Eur. Respir. J. 19: 538-545.
-
(2002)
Eur. Respir. J.
, vol.19
, pp. 538-545
-
-
Holt, P.G.1
Sly, P.D.2
-
63
-
-
0037436868
-
Regulation of cryopyrin/Pypaf1 signaling by pyrin, the familial Mediterranean fever gene product
-
Dowds, T. A., J. Masumoto, F. F. Chen, Y. Ogura, N. Inohara, and G. Nunez. 2003. Regulation of cryopyrin/Pypaf1 signaling by pyrin, the familial Mediterranean fever gene product. Biochem. Biophys. Res. Commun. 302: 575-580.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.302
, pp. 575-580
-
-
Dowds, T.A.1
Masumoto, J.2
Chen, F.F.3
Ogura, Y.4
Inohara, N.5
Nunez, G.6
-
64
-
-
2542452727
-
Cryopyrin-induced interleukin 1β secretion in monocytic cells: Enhanced activity of disease-associated mutants and requirement for ASC
-
Dowds, T. A., J. Masumoto, L. Zhu, N. Inohara, and G. Nunez. 2004. Cryopyrin-induced interleukin 1β secretion in monocytic cells: enhanced activity of disease-associated mutants and requirement for ASC. J. Biol. Chem. 279: 21924-21928.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 21924-21928
-
-
Dowds, T.A.1
Masumoto, J.2
Zhu, L.3
Inohara, N.4
Nunez, G.5
-
65
-
-
1642285783
-
NALP3 forms an IL-1β-processing inflammasome with increased acrivity in Muckle-Wells autoinflammatory disorder
-
Agostini, L., F. Martinon, K. Burns, M. F. McDermott, P. N. Hawkins, and J. Tschopp. 2004. NALP3 forms an IL-1β-processing inflammasome with increased acrivity in Muckle-Wells autoinflammatory disorder. Immunity 20: 319-325.
-
(2004)
Immunity
, vol.20
, pp. 319-325
-
-
Agostini, L.1
Martinon, F.2
Burns, K.3
McDermott, M.F.4
Hawkins, P.N.5
Tschopp, J.6
-
66
-
-
8444225132
-
Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist
-
Hoffman, H. M., S. Rosengren, D. L. Boyle, J. Y. Cho, J. Nayar, J. L. Mueller, J. P. Anderson, A. A. Wanderer, and G. S. Firestein. 2004. Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist. Lancet 364: 1779-1785.
-
(2004)
Lancet
, vol.364
, pp. 1779-1785
-
-
Hoffman, H.M.1
Rosengren, S.2
Boyle, D.L.3
Cho, J.Y.4
Nayar, J.5
Mueller, J.L.6
Anderson, J.P.7
Wanderer, A.A.8
Firestein, G.S.9
|