메뉴 건너뛰기




Volumn , Issue 233, 2006, Pages

Environmental health criteria for transgenic animal mutagenicity assays

(15)  Chen, T a   Dean, S b   Douglas, G R c   Heddle, J A d   Lambert, I B e   Nohmi, T f   Sykes, P J g   Thybaud, V h   Valentine, C R a   Van Benthem, J i   Bitsch, A j   Kielhorn, J j   Mangelsdorf, I j   Vickers, C k   Wahnschaffe, U j  


Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; CELLS; DETECTORS; DNA; DRUG DOSAGE; OPTIMIZATION; TOXICITY;

EID: 33847096900     PISSN: 0250863X     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Review
Times cited : (1)

References (451)
  • 3
    • 0023871944 scopus 로고
    • Species-specific response to the rodent carcinogens 1,2-dimethylhydrazine and 1,2-dibromo-3-chloropropane in rodent bone-marrow micronucleus assays
    • Albanese R, Mirkova E, Gatehouse D & Ashby J (1988) Species-specific response to the rodent carcinogens 1,2-dimethylhydrazine and 1,2-dibromo-3-chloropropane in rodent bone-marrow micronucleus assays. Mutagenesis, 3(1): 35-38.
    • (1988) Mutagenesis , vol.3 , Issue.1 , pp. 35-38
    • Albanese, R.1    Mirkova, E.2    Gatehouse, D.3    Ashby, J.4
  • 4
    • 0036955119 scopus 로고    scopus 로고
    • High accumulation of oxidative DNA damage, 8-hydroxyguanine
    • deficient mice by chronic oxidative stress. Carcinogenesis, 2010
    • Arai T, Kelly VP, Minowa O, Noda T & Nishimura S (2002) High accumulation of oxidative DNA damage, 8-hydroxyguanine, in Mmh/Ogg1 deficient mice by chronic oxidative stress. Carcinogenesis, 23: 2005-2010.
    • (2002) Mmh/Ogg1 , vol.23
    • Arai, T.1    Kelly, V.P.2    Minowa, O.3    Noda, T.4    Nishimura, S.5
  • 5
    • 0042172927 scopus 로고    scopus 로고
    • Cell proliferation in liver of Mmh/Ogg1-deficient mice enhances mutation frequency because of the presence of 8-hydroxyguanine in DNA
    • Arai T, Kelly VP, Komoro K, Minowa O, Noda T & Nishimura S (2003) Cell proliferation in liver of Mmh/Ogg1-deficient mice enhances mutation frequency because of the presence of 8-hydroxyguanine in DNA. Cancer Res, 63: 4287-4292.
    • (2003) Cancer Res , vol.63 , pp. 4287-4292
    • Arai, T.1    Kelly, V.P.2    Komoro, K.3    Minowa, O.4    Noda, T.5    Nishimura, S.6
  • 6
    • 13644252601 scopus 로고
    • Micronuclei induction of methyl bromide in rats and mice by sub-chronic inhalation toxicity test
    • Araki A, Kato F, Matsushima T, Ikawa N & Nozaki K (1995) Micronuclei induction of methyl bromide in rats and mice by sub-chronic inhalation toxicity test. Environ Mutagen Res Commun, 17(1): 47-56.
    • (1995) Environ Mutagen Res Commun , vol.17 , Issue.1 , pp. 47-56
    • Araki, A.1    Kato, F.2    Matsushima, T.3    Ikawa, N.4    Nozaki, K.5
  • 7
    • 2442546368 scopus 로고    scopus 로고
    • DNA adducts and mutagenic specificity of the ubiquitous environmental pollutant 3-nitrobenzanthrone in Muta™Mouse
    • Arlt VM, Zhan L, Schmeiser HH, Honma M, Hayashi M, Phillips DH & Suzuki T (2004) DNA adducts and mutagenic specificity of the ubiquitous environmental pollutant 3-nitrobenzanthrone in Muta™Mouse. Environ Mol Mutagen, 43(3): 186-195.
    • (2004) Environ Mol Mutagen , vol.43 , Issue.3 , pp. 186-195
    • Arlt, V.M.1    Zhan, L.2    Schmeiser, H.H.3    Honma, M.4    Hayashi, M.5    Phillips, D.H.6    Suzuki, T.7
  • 10
    • 0030926723 scopus 로고    scopus 로고
    • Mutation assays in male germ cells from transgenic mice: Overview of study and conclusions
    • Ashby J, Gorelick NJ & Shelby MD (1997) Mutation assays in male germ cells from transgenic mice: overview of study and conclusions. Mutat Res, 388: 111-122.
    • (1997) Mutat Res , vol.388 , pp. 111-122
    • Ashby, J.1    Gorelick, N.J.2    Shelby, M.D.3
  • 12
    • 0029686554 scopus 로고    scopus 로고
    • Aflatoxin B1 induced lacI mutation in liver and kidney of transgenic mice C57BL/6N: Effect of phorone
    • Autrup H, Jorgensen ECB & Jensen O (1996) Aflatoxin B1 induced lacI mutation in liver and kidney of transgenic mice C57BL/6N: effect of phorone. Mutagenesis, 11: 69-73.
    • (1996) Mutagenesis , vol.11 , pp. 69-73
    • Autrup, H.1    Jorgensen, E.C.B.2    Jensen, O.3
  • 13
    • 0027285855 scopus 로고
    • Molecular analysis of ethylene oxide-induced mutations at the HPRT locus in human diploid fibroblasts
    • Bastlová T, Andersson B, Lambert B & Kolman A (1993) Molecular analysis of ethylene oxide-induced mutations at the HPRT locus in human diploid fibroblasts. Mutat Res, 287: 283-292.
    • (1993) Mutat Res , vol.287 , pp. 283-292
    • Bastlová, T.1    Andersson, B.2    Lambert, B.3    Kolman, A.4
  • 15
    • 0037938687 scopus 로고    scopus 로고
    • Weak yet distinct mutagenicity of acrylamide in mammalian cells
    • Besaratinia A & Pfeifer GP (2003) Weak yet distinct mutagenicity of acrylamide in mammalian cells. J Natl Cancer Inst, 95(12): 889-896.
    • (2003) J Natl Cancer Inst , vol.95 , Issue.12 , pp. 889-896
    • Besaratinia, A.1    Pfeifer, G.P.2
  • 16
    • 3242690880 scopus 로고    scopus 로고
    • Genotoxicity of acrylamide and glycidamide
    • Besaratinia A & Pfeifer GP (2004) Genotoxicity of acrylamide and glycidamide. J Natl Cancer Inst, 96(13): 1023-1029.
    • (2004) J Natl Cancer Inst , vol.96 , Issue.13 , pp. 1023-1029
    • Besaratinia, A.1    Pfeifer, G.P.2
  • 17
    • 3042519214 scopus 로고    scopus 로고
    • G-to-T transversions and small tandem base deletions are hallmark of mutations induced by ultraviolet A radiation in mammalian cells
    • Besaratinia A, Synold TW, Xi B & Pfeifer GP (2004) G-to-T transversions and small tandem base deletions are hallmark of mutations induced by ultraviolet A radiation in mammalian cells. Biochemistry (Washington), 43(25): 8169-8177.
    • (2004) Biochemistry (Washington) , vol.43 , Issue.25 , pp. 8169-8177
    • Besaratinia, A.1    Synold, T.W.2    Xi, B.3    Pfeifer, G.P.4
  • 18
    • 33846354546 scopus 로고    scopus 로고
    • A more efficient Big Blue® protocol improves transgene rescue and accuracy in an adduct and mutation measurement
    • Bielas JH (2002) A more efficient Big Blue® protocol improves transgene rescue and accuracy in an adduct and mutation measurement. Mutat Res, 518(2): 107-112.
    • (2002) Mutat Res , vol.518 , Issue.2 , pp. 107-112
    • Bielas, J.H.1
  • 19
    • 0034633645 scopus 로고    scopus 로고
    • Proliferation is necessary for both repair and mutation in transgenic mouse cells
    • Bielas JH & Heddle JA (2000) Proliferation is necessary for both repair and mutation in transgenic mouse cells. Proc Natl Acad Sci USA, 97(21): 11391-11396.
    • (2000) Proc Natl Acad Sci USA , vol.97 , Issue.21 , pp. 11391-11396
    • Bielas, J.H.1    Heddle, J.A.2
  • 20
    • 0028986405 scopus 로고
    • Cytogenetic mapping of lambda gt10 lacZ sequences in transgenic mouse strain 40.6 (Muta™Mouse)
    • Blakey DH, Douglas GR, Huang KC & Winter HI (1995) Cytogenetic mapping of lambda gt10 lacZ sequences in transgenic mouse strain 40.6 (Muta™Mouse). Mutagenesis, 10: 145-148.
    • (1995) Mutagenesis , vol.10 , pp. 145-148
    • Blakey, D.H.1    Douglas, G.R.2    Huang, K.C.3    Winter, H.I.4
  • 21
    • 0032749588 scopus 로고    scopus 로고
    • Treatment of lacZ plasmid-based transgenic mice with benzo[a]pyrene: Measurement of DNA adduct levels, mutant frequencies, and mutant spectra
    • Boerrigter ME (1999) Treatment of lacZ plasmid-based transgenic mice with benzo[a]pyrene: measurement of DNA adduct levels, mutant frequencies, and mutant spectra. Environ Mol Mutagen, 34: 140-147.
    • (1999) Environ Mol Mutagen , vol.34 , pp. 140-147
    • Boerrigter, M.E.1
  • 23
    • 0033977633 scopus 로고    scopus 로고
    • Mutational analysis of the liver, colon and kidney of Big Blue® rats treated with 2-amino-3-methylimidazo[4,5-f]quinoline
    • Bol SA, Horlbeck J, Markovic J, de Boer JG, Turesky RJ & Constable A (2000) Mutational analysis of the liver, colon and kidney of Big Blue® rats treated with 2-amino-3-methylimidazo[4,5-f]quinoline. Carcinogenesis, 21: 1-6.
    • (2000) Carcinogenesis , vol.21 , pp. 1-6
    • Bol, S.A.1    Horlbeck, J.2    Markovic, J.3    de Boer, J.G.4    Turesky, R.J.5    Constable, A.6
  • 24
    • 10844241185 scopus 로고    scopus 로고
    • Mammary carcinogenesis and molecular analysis of in vivo cII gene mutations in the mammary tissue of female transgenic rats treated with the environmental pollutant 6-nitrochrysene
    • Boyiri T, Guttenplan J, Khmelnitsky M, Kosinska W, Lin JM, Desai D, Amin S, Pittman B & El-Bayoumy K (2004) Mammary carcinogenesis and molecular analysis of in vivo cII gene mutations in the mammary tissue of female transgenic rats treated with the environmental pollutant 6-nitrochrysene. Carcinogenesis, 25(4): 637-643.
    • (2004) Carcinogenesis , vol.25 , Issue.4 , pp. 637-643
    • Boyiri, T.1    Guttenplan, J.2    Khmelnitsky, M.3    Kosinska, W.4    Lin, J.M.5    Desai, D.6    Amin, S.7    Pittman, B.8    El-Bayoumy, K.9
  • 25
    • 0029952252 scopus 로고    scopus 로고
    • Tissue-specific induction of mutations by acute oral administration of N-methyl-N′-nitro-N-nitrosoguanidine and β-propiolactone to the Muta™Mouse: Preliminary data on stomach, liver and bone marrow
    • Brault D, Bouilly C, Renault D & Thybaud V (1996) Tissue-specific induction of mutations by acute oral administration of N-methyl-N′-nitro-N-nitrosoguanidine and β-propiolactone to the Muta™Mouse: preliminary data on stomach, liver and bone marrow. Mutat Res, 360: 83-87.
    • (1996) Mutat Res , vol.360 , pp. 83-87
    • Brault, D.1    Bouilly, C.2    Renault, D.3    Thybaud, V.4
  • 26
    • 0029813035 scopus 로고    scopus 로고
    • Detection of gene mutation in skin, stomach and liver of Muta™Mouse following oral or topical treatment with N-methyl-N′-nitro-N-nitrosoguanidine or 1-chloromethylpyrene: Some preliminary observations
    • Brooks TM & Dean SW (1996) Detection of gene mutation in skin, stomach and liver of Muta™Mouse following oral or topical treatment with N-methyl-N′-nitro-N-nitrosoguanidine or 1-chloromethylpyrene: some preliminary observations. Mutagenesis, 11: 529-532.
    • (1996) Mutagenesis , vol.11 , pp. 529-532
    • Brooks, T.M.1    Dean, S.W.2
  • 27
    • 0030922275 scopus 로고    scopus 로고
    • The detection of gene mutation in the tubular sperm of Muta™Mice following a single intraperitoneal treatment with methyl methanesulphonate or ethylnitrosourea
    • Brooks TM & Dean SW (1997) The detection of gene mutation in the tubular sperm of Muta™Mice following a single intraperitoneal treatment with methyl methanesulphonate or ethylnitrosourea. Mutat Res, 388: 219-222.
    • (1997) Mutat Res , vol.388 , pp. 219-222
    • Brooks, T.M.1    Dean, S.W.2
  • 28
    • 0028941311 scopus 로고
    • The detection of gene mutation in transgenic mice (Muta™Mouse) following a single oral dose of 2-acetylaminofluorene
    • Brooks TM, Szegedi M, Rosher P & Dean SW (1995) The detection of gene mutation in transgenic mice (Muta™Mouse) following a single oral dose of 2-acetylaminofluorene. Mutagenesis, 10: 149-150.
    • (1995) Mutagenesis , vol.10 , pp. 149-150
    • Brooks, T.M.1    Szegedi, M.2    Rosher, P.3    Dean, S.W.4
  • 29
    • 33847128336 scopus 로고    scopus 로고
    • Hydrazin, Hydrazinhydrat und Hydrazinsulfate. Beratergremium für umweltrelevante Altstoffe. Stuttgart, S. Hirzel Wissenschaftliche Verlagsgesellschaft
    • BUA , No. 205
    • BUA (1996) Hydrazin, Hydrazinhydrat und Hydrazinsulfate. Beratergremium für umweltrelevante Altstoffe. Stuttgart, S. Hirzel Wissenschaftliche Verlagsgesellschaft, pp 1-179 (BUA Report No. 205).
    • (1996) pp 1-179 (BUA Report
  • 30
    • 0030855899 scopus 로고    scopus 로고
    • Spontaneous mutation frequencies and spectra in p53(+/+) and p53(-/-) mice: A test of the "guardian of the genome" hypothesis in the Big Blue® transgenic mouse mutation detection system
    • Buettner VL, Nishino H, Haavik J, Knoll A, Hill K & Sommer SS (1997) Spontaneous mutation frequencies and spectra in p53(+/+) and p53(-/-) mice: a test of the "guardian of the genome" hypothesis in the Big Blue® transgenic mouse mutation detection system. Mutat Res, 379(1): 13-20.
    • (1997) Mutat Res , vol.379 , Issue.1 , pp. 13-20
    • Buettner, V.L.1    Nishino, H.2    Haavik, J.3    Knoll, A.4    Hill, K.5    Sommer, S.S.6
  • 31
    • 0032769369 scopus 로고    scopus 로고
    • Tandem-base mutations occur in mouse liver and adipose tissue preferentially as G:C→T:A transversions and accumulate with age
    • Buettner VL, Hill KA, Halangoda A & Sommer SS (1999) Tandem-base mutations occur in mouse liver and adipose tissue preferentially as G:C→T:A transversions and accumulate with age. Environ Mol Mutagen, 33(4): 320-324.
    • (1999) Environ Mol Mutagen , vol.33 , Issue.4 , pp. 320-324
    • Buettner, V.L.1    Hill, K.A.2    Halangoda, A.3    Sommer, S.S.4
  • 32
    • 0027170192 scopus 로고
    • ENU-induced mutagenesis at a single A-T base pair in transgenic mice containing Phi-X174
    • Burkhart JG, Burkhart BA, Sampson KS & Malling HV (1993) ENU-induced mutagenesis at a single A-T base pair in transgenic mice containing Phi-X174. Mutat Res, 292: 69-81.
    • (1993) Mutat Res , vol.292 , pp. 69-81
    • Burkhart, J.G.1    Burkhart, B.A.2    Sampson, K.S.3    Malling, H.V.4
  • 34
    • 0031842936 scopus 로고    scopus 로고
    • Databases and software for the analysis of mutations in the human p53 gene, human hprt gene and both the lacI and lacZ gene in transgenic rodents
    • Cariello NF, Douglas GR, Gorelick NJ, Hart DW, Wilson JD & Soussi T (1998) Databases and software for the analysis of mutations in the human p53 gene, human hprt gene and both the lacI and lacZ gene in transgenic rodents. Nucl Acids Res, 26: 198-199.
    • (1998) Nucl Acids Res , vol.26 , pp. 198-199
    • Cariello, N.F.1    Douglas, G.R.2    Gorelick, N.J.3    Hart, D.W.4    Wilson, J.D.5    Soussi, T.6
  • 35
    • 0028625585 scopus 로고
    • Statistical tests of significance in transgenic mutation assays: Considerations on the experimental unit
    • Carr GJ & Gorelick NJ (1994) Statistical tests of significance in transgenic mutation assays: considerations on the experimental unit. Environ Mol Mutagen, 24(4): 276-282.
    • (1994) Environ Mol Mutagen , vol.24 , Issue.4 , pp. 276-282
    • Carr, G.J.1    Gorelick, N.J.2
  • 36
    • 0029038488 scopus 로고
    • Statistical design and analysis of mutation studies in transgenic mice
    • Carr GJ & Gorelick NJ (1995) Statistical design and analysis of mutation studies in transgenic mice. Environ Mol Mutagen, 25(3): 246-255.
    • (1995) Environ Mol Mutagen , vol.25 , Issue.3 , pp. 246-255
    • Carr, G.J.1    Gorelick, N.J.2
  • 37
    • 0030601853 scopus 로고    scopus 로고
    • Carr GJ & Gorelick NJ (1996) A place for statistics in the generation and analysis of genetic toxicity data: a response to rodent mutation assay data presentation and statistical assessment. Mutat Res, 357(1-2): 257-260.
    • Carr GJ & Gorelick NJ (1996) A place for statistics in the generation and analysis of genetic toxicity data: a response to "rodent mutation assay data presentation and statistical assessment." Mutat Res, 357(1-2): 257-260.
  • 38
    • 0033396678 scopus 로고    scopus 로고
    • Hprt mutant frequency and molecular analysis of Hprt mutations in rats treated with mutagenic carcinogens
    • Casciano DA, Aidoo A, Chen T, Mittelstaedt RA, Manjanatha MG & Heflich RH (1999) Hprt mutant frequency and molecular analysis of Hprt mutations in rats treated with mutagenic carcinogens. Mutat Res, 431: 389-395.
    • (1999) Mutat Res , vol.431 , pp. 389-395
    • Casciano, D.A.1    Aidoo, A.2    Chen, T.3    Mittelstaedt, R.A.4    Manjanatha, M.G.5    Heflich, R.H.6
  • 39
    • 33847114377 scopus 로고    scopus 로고
    • CCRIS (1995a) 4-Acetylaminofluorene. CAS: 28322-02-3. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Chemical Carcinogenesis Research Information System (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?CCRIS).
    • CCRIS (1995a) 4-Acetylaminofluorene. CAS: 28322-02-3. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Chemical Carcinogenesis Research Information System (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?CCRIS).
  • 40
    • 33847112430 scopus 로고    scopus 로고
    • CCRIS (1995b) Beta-Propiolactone. CAS: 57-57-8. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Chemical Carcinogenesis Research Information System (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?CCRIS).
    • CCRIS (1995b) Beta-Propiolactone. CAS: 57-57-8. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Chemical Carcinogenesis Research Information System (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?CCRIS).
  • 41
    • 33847095020 scopus 로고    scopus 로고
    • CCRIS (1995c) Chlorambucil. CAS: 305-03-3. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Chemical Carcinogenesis Research Information System (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?CCRIS).
    • CCRIS (1995c) Chlorambucil. CAS: 305-03-3. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Chemical Carcinogenesis Research Information System (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?CCRIS).
  • 42
    • 33847144497 scopus 로고    scopus 로고
    • CCRIS (1996) Acrylamide. CAS: 79-06-1. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Chemical Carcinogenesis Research Information System (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?CCRIS).
    • CCRIS (1996) Acrylamide. CAS: 79-06-1. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Chemical Carcinogenesis Research Information System (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?CCRIS).
  • 43
    • 33847142727 scopus 로고    scopus 로고
    • CCRIS (2000) N-Propyl-N-nitrosourea. CAS: 816-57-9. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Chemical Carcinogenesis Research Information System (http://toxnet.nlm.nih.gov/cgi-bin/ sis/htmlgen?CCRIS).
    • CCRIS (2000) N-Propyl-N-nitrosourea. CAS: 816-57-9. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Chemical Carcinogenesis Research Information System (http://toxnet.nlm.nih.gov/cgi-bin/ sis/htmlgen?CCRIS).
  • 44
    • 33847115271 scopus 로고    scopus 로고
    • CCRIS (2001a) Ethyl methanesulfonate. CAS: 62-50-0. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Chemical Carcinogenesis Research Information System (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?CCRIS).
    • CCRIS (2001a) Ethyl methanesulfonate. CAS: 62-50-0. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Chemical Carcinogenesis Research Information System (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?CCRIS).
  • 45
    • 33847126925 scopus 로고    scopus 로고
    • CCRIS (2001b) Methyl bromide. CAS: 74-83-9. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Chemical Carcinogenesis Research Information System (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?CCRIS).
    • CCRIS (2001b) Methyl bromide. CAS: 74-83-9. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Chemical Carcinogenesis Research Information System (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?CCRIS).
  • 46
    • 33847130480 scopus 로고    scopus 로고
    • CCRIS (2001c) Tris(2,3-Dibromopropyl)phosphate. CAS: 126-72-7. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Chemical Carcinogenesis Research Information System (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen? CCRIS).
    • CCRIS (2001c) Tris(2,3-Dibromopropyl)phosphate. CAS: 126-72-7. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Chemical Carcinogenesis Research Information System (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen? CCRIS).
  • 47
    • 33847136339 scopus 로고    scopus 로고
    • CCRIS (2001d) Tamoxifen. CAS: 10540-29-1. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Chemical Carcinogenesis Research Information System (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?CCRIS).
    • CCRIS (2001d) Tamoxifen. CAS: 10540-29-1. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Chemical Carcinogenesis Research Information System (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?CCRIS).
  • 48
    • 33847166155 scopus 로고    scopus 로고
    • CCRIS (2002a) 7,12-Dimethylbenz[a]anthracene. CAS: 57-97-6. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Chemical Carcinogenesis Research Information System (http://toxnet.nlm.nih.gov/cgi-bin/ sis/htmlgen?CCRIS).
    • CCRIS (2002a) 7,12-Dimethylbenz[a]anthracene. CAS: 57-97-6. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Chemical Carcinogenesis Research Information System (http://toxnet.nlm.nih.gov/cgi-bin/ sis/htmlgen?CCRIS).
  • 49
    • 33847152115 scopus 로고    scopus 로고
    • CCRIS (2002b) Mitomycin C. CAS: 50-07-7. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Chemical Carcinogenesis Research Information System (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?CCRIS).
    • CCRIS (2002b) Mitomycin C. CAS: 50-07-7. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Chemical Carcinogenesis Research Information System (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?CCRIS).
  • 50
    • 33847097200 scopus 로고    scopus 로고
    • CCRIS (2002c) N,N-Dipropylnitrosamine. CAS: 621-64-7. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Chemical Carcinogenesis Research Information System (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen? CCRIS).
    • CCRIS (2002c) N,N-Dipropylnitrosamine. CAS: 621-64-7. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Chemical Carcinogenesis Research Information System (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen? CCRIS).
  • 51
    • 33847094595 scopus 로고    scopus 로고
    • CCRIS (2003a) 4-Aminobiphenyl. CAS: 92-67-1. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Chemical Carcinogenesis Research Information System (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?CCRIS).
    • CCRIS (2003a) 4-Aminobiphenyl. CAS: 92-67-1. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Chemical Carcinogenesis Research Information System (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?CCRIS).
  • 52
    • 33847137699 scopus 로고    scopus 로고
    • CCRIS (2003b) 4-Nitroquinoline 1-oxide. CAS: 56-57-5. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Chemical Carcinogenesis Research Information System (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?CCRIS).
    • CCRIS (2003b) 4-Nitroquinoline 1-oxide. CAS: 56-57-5. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Chemical Carcinogenesis Research Information System (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?CCRIS).
  • 53
    • 33847149622 scopus 로고    scopus 로고
    • CCRIS (2003c) Benzo[a]pyrene. CAS: 50-32-8. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Chemical Carcinogenesis Research Information System (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?CCRIS).
    • CCRIS (2003c) Benzo[a]pyrene. CAS: 50-32-8. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Chemical Carcinogenesis Research Information System (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?CCRIS).
  • 54
    • 33847144926 scopus 로고    scopus 로고
    • CCRIS (2003d) N,N-Diethylnitrosamine. CAS: 55-18-5. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Chemical Carcinogenesis Research Information System (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen? CCRIS).
    • CCRIS (2003d) N,N-Diethylnitrosamine. CAS: 55-18-5. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Chemical Carcinogenesis Research Information System (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen? CCRIS).
  • 55
    • 33847163579 scopus 로고    scopus 로고
    • CCRIS (2003e) Quinoline. CAS: 91-22-5. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Chemical Carcinogenesis Research Information System (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?CCRIS).
    • CCRIS (2003e) Quinoline. CAS: 91-22-5. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Chemical Carcinogenesis Research Information System (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?CCRIS).
  • 56
    • 33847154575 scopus 로고    scopus 로고
    • CCRIS (2003f) 4-(N-Methyl-N-nitrosamino)-1-(3-pyridyl)-1- butanone. CAS: 64091-91-4. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Chemical Carcinogenesis Research Information System (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?CCRIS).
    • CCRIS (2003f) 4-(N-Methyl-N-nitrosamino)-1-(3-pyridyl)-1- butanone. CAS: 64091-91-4. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Chemical Carcinogenesis Research Information System (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?CCRIS).
  • 58
    • 0032882465 scopus 로고    scopus 로고
    • Development of a mouse cell line containing the ΦX174 am3 allele as a target for detecting mutation
    • Chen JB, Dobrovolsky VN & Heflich RH (1999) Development of a mouse cell line containing the ΦX174 am3 allele as a target for detecting mutation. Mutat Res, 444: 347-353.
    • (1999) Mutat Res , vol.444 , pp. 347-353
    • Chen, J.B.1    Dobrovolsky, V.N.2    Heflich, R.H.3
  • 59
    • 0032541153 scopus 로고    scopus 로고
    • Comparison of mutant frequencies and types of mutations induced by thiotepa in the endogenous Hprt gene and transgenic lacI gene of Big Blue® rats
    • Chen T, Aidoo A, Manjanatha MG, Mittelstaedt RA, Shelton SD, Lyn-Cook LE, Casciano DA & Heflich RH (1998) Comparison of mutant frequencies and types of mutations induced by thiotepa in the endogenous Hprt gene and transgenic lacI gene of Big Blue® rats. Mutat Res, 403: 199-214.
    • (1998) Mutat Res , vol.403 , pp. 199-214
    • Chen, T.1    Aidoo, A.2    Manjanatha, M.G.3    Mittelstaedt, R.A.4    Shelton, S.D.5    Lyn-Cook, L.E.6    Casciano, D.A.7    Heflich, R.H.8
  • 60
    • 0034744174 scopus 로고    scopus 로고
    • Comparison of Hprt and lacI mutant frequency with DNA adduct formation in N-hydroxy-2-acetylaminofluorene- treated Big Blue® rats
    • Chen T, Mittelstaedt RA, Aidoo A, Hamilton LP, Beland FA, Casciano DA & Heflich RH (2001a) Comparison of Hprt and lacI mutant frequency with DNA adduct formation in N-hydroxy-2-acetylaminofluorene- treated Big Blue® rats. Environ Mol Mutagen, 37(3): 195-202.
    • (2001) Environ Mol Mutagen , vol.37 , Issue.3 , pp. 195-202
    • Chen, T.1    Mittelstaedt, R.A.2    Aidoo, A.3    Hamilton, L.P.4    Beland, F.A.5    Casciano, D.A.6    Heflich, R.H.7
  • 63
    • 0028157494 scopus 로고
    • Somatic mutant frequency, mutation rates and mutational spectra in the human population in vivo
    • Cole J & Skopek TR (1994) Somatic mutant frequency, mutation rates and mutational spectra in the human population in vivo. Mutat Res, 304: 33-105.
    • (1994) Mutat Res , vol.304 , pp. 33-105
    • Cole, J.1    Skopek, T.R.2
  • 64
    • 0032965173 scopus 로고    scopus 로고
    • A comparison of the effects of diverse mutagens at the lacZ transgene and Dlb-1 locus in vivo
    • Cosentino L & Heddle JA (1999) A comparison of the effects of diverse mutagens at the lacZ transgene and Dlb-1 locus in vivo. Mutagenesis, 14: 113-119.
    • (1999) Mutagenesis , vol.14 , pp. 113-119
    • Cosentino, L.1    Heddle, J.A.2
  • 65
    • 0034613927 scopus 로고    scopus 로고
    • Differential mutation of transgenic and endogenous loci in vivo
    • Cosentino L & Heddle JA (2000) Differential mutation of transgenic and endogenous loci in vivo. Mutat Res, 454(1-2): 1-10.
    • (2000) Mutat Res , vol.454 , Issue.1-2 , pp. 1-10
    • Cosentino, L.1    Heddle, J.A.2
  • 66
    • 0022873586 scopus 로고
    • In vivo sister chromatid exchange and micronucleus induction studies with 1,3-butadiene in B6C3F1 mice and Sprague-Dawley rats
    • Cunningham MJ, Choy WN, Arce GT, Rickard LB, Vlachos DA, Kinney LA & Sarrif AM (1986) In vivo sister chromatid exchange and micronucleus induction studies with 1,3-butadiene in B6C3F1 mice and Sprague-Dawley rats. Mutagenesis, 1: 449-452.
    • (1986) Mutagenesis , vol.1 , pp. 449-452
    • Cunningham, M.J.1    Choy, W.N.2    Arce, G.T.3    Rickard, L.B.4    Vlachos, D.A.5    Kinney, L.A.6    Sarrif, A.M.7
  • 67
    • 0029991783 scopus 로고    scopus 로고
    • Distinction of mutagenic carcinogens from a mutagenic noncarcinogen in the Big Blue® transgenic mouse
    • Cunningham ML, Hayward JJ, Shane BS & Tindall KR (1996) Distinction of mutagenic carcinogens from a mutagenic noncarcinogen in the Big Blue® transgenic mouse. Environ Health Perspect, 104: 683-686.
    • (1996) Environ Health Perspect , vol.104 , pp. 683-686
    • Cunningham, M.L.1    Hayward, J.J.2    Shane, B.S.3    Tindall, K.R.4
  • 68
    • 0037039714 scopus 로고    scopus 로고
    • Induction of lacI mutations in Big Blue® rats treated with tamoxifen and α-hydroxytamoxifen
    • da Costa GG, Manjanatha MG, Marques MM & Beland FA (2002) Induction of lacI mutations in Big Blue® rats treated with tamoxifen and α-hydroxytamoxifen. Cancer Lett, 176(1): 37-45.
    • (2002) Cancer Lett , vol.176 , Issue.1 , pp. 37-45
    • da Costa, G.G.1    Manjanatha, M.G.2    Marques, M.M.3    Beland, F.A.4
  • 70
    • 0032814944 scopus 로고    scopus 로고
    • Tamoxifen induces G:C→T:A mutations in the cII gene in the liver of λ/lacI transgenic rats but not at 5′-CpG-3′ dinucleotide sequences as found in the lacI transgene
    • Davies R, Gant TW, Smith LL & Styles JA (1999) Tamoxifen induces G:C→T:A mutations in the cII gene in the liver of λ/lacI transgenic rats but not at 5′-CpG-3′ dinucleotide sequences as found in the lacI transgene. Carcinogenesis, 20: 1351-1356.
    • (1999) Carcinogenesis , vol.20 , pp. 1351-1356
    • Davies, R.1    Gant, T.W.2    Smith, L.L.3    Styles, J.A.4
  • 71
    • 0030599151 scopus 로고    scopus 로고
    • In vivo mutagenicity and DNA adduct levels of heterocyclic amines in Muta™Mice and c-myc/lacZ double transgenic mice
    • Davis CD, Dacquel EJ, Schut HAJ, Thorgeirsson SS & Snyderwine EG (1996) In vivo mutagenicity and DNA adduct levels of heterocyclic amines in Muta™Mice and c-myc/lacZ double transgenic mice. Mutat Res, 356: 287-296.
    • (1996) Mutat Res , vol.356 , pp. 287-296
    • Davis, C.D.1    Dacquel, E.J.2    Schut, H.A.J.3    Thorgeirsson, S.S.4    Snyderwine, E.G.5
  • 73
    • 0032936730 scopus 로고    scopus 로고
    • Transgenic mouse mutation assay systems can play an important role in regulatory mutagenicity testing in vivo for the detection of site-of-contact mutagens
    • Dean SW, Brooks TM, Burlinson B, Mirsalis J, Myhr B, Recio L & Thybaud V (1999) Transgenic mouse mutation assay systems can play an important role in regulatory mutagenicity testing in vivo for the detection of site-of-contact mutagens. Mutagenesis, 14(1): 141-151.
    • (1999) Mutagenesis , vol.14 , Issue.1 , pp. 141-151
    • Dean, S.W.1    Brooks, T.M.2    Burlinson, B.3    Mirsalis, J.4    Myhr, B.5    Recio, L.6    Thybaud, V.7
  • 74
    • 0031953259 scopus 로고    scopus 로고
    • The lacI gene as a target for mutation in transgenic rodents and Escherichia coli
    • de Boer JG & Glickman BW (1998) The lacI gene as a target for mutation in transgenic rodents and Escherichia coli. Genetics, 148: 1441-1451.
    • (1998) Genetics , vol.148 , pp. 1441-1451
    • de Boer, J.G.1    Glickman, B.W.2
  • 75
    • 0030329708 scopus 로고    scopus 로고
    • Spectrum of mutations in kidney, stomach, and liver from lacI transgenic mice recovered after treatment with tris(2,3-dibromopropyl)phosphate
    • de Boer JG, Mirsalis JC, Provost GS, Tindall KR & Glickman BW (1996) Spectrum of mutations in kidney, stomach, and liver from lacI transgenic mice recovered after treatment with tris(2,3-dibromopropyl)phosphate. Environ Mol Mutagen, 28: 418-423.
    • (1996) Environ Mol Mutagen , vol.28 , pp. 418-423
    • de Boer, J.G.1    Mirsalis, J.C.2    Provost, G.S.3    Tindall, K.R.4    Glickman, B.W.5
  • 77
    • 33847125260 scopus 로고    scopus 로고
    • DECOS (1989) Health-based recommended occupational exposure limits for ethyl methanesulphonate (EMS) methyl methanesulphonate (MMS). Voorburg, Directorate-General of Labour, Dutch Expert Committee for Occupational Standards, pp 1-73 (RA 4/89).
    • DECOS (1989) Health-based recommended occupational exposure limits for ethyl methanesulphonate (EMS) methyl methanesulphonate (MMS). Voorburg, Directorate-General of Labour, Dutch Expert Committee for Occupational Standards, pp 1-73 (RA 4/89).
  • 78
    • 0033032939 scopus 로고    scopus 로고
    • An estimator of the mutant frequency in assays using transgenic animals
    • Delongchamp RR, Malling HV, Chen JB & Heflich RH (1999) An estimator of the mutant frequency in assays using transgenic animals. Mutat Res, 440: 101-108.
    • (1999) Mutat Res , vol.440 , pp. 101-108
    • Delongchamp, R.R.1    Malling, H.V.2    Chen, J.B.3    Heflich, R.H.4
  • 79
    • 0034945511 scopus 로고    scopus 로고
    • Estimation of the average burst size of ΦX174 am3, cs70 for use in mutation assays with transgenic mice
    • Delongchamp RR, Valentine CR & Malling HV (2001) Estimation of the average burst size of ΦX174 am3, cs70 for use in mutation assays with transgenic mice. Environ Mol Mutagen, 37: 356-360.
    • (2001) Environ Mol Mutagen , vol.37 , pp. 356-360
    • Delongchamp, R.R.1    Valentine, C.R.2    Malling, H.V.3
  • 80
    • 0033781210 scopus 로고    scopus 로고
    • Defining the roles of nucleotide excision repair and recombination in the repair of DNA interstrand cross-links in mammalian cells
    • De Silva IU, McHugh PJ, Clingen PH & Hartley JA (2000) Defining the roles of nucleotide excision repair and recombination in the repair of DNA interstrand cross-links in mammalian cells. Mol Cell Biol, 20(21): 7980-7990.
    • (2000) Mol Cell Biol , vol.20 , Issue.21 , pp. 7980-7990
    • De Silva, I.U.1    McHugh, P.J.2    Clingen, P.H.3    Hartley, J.A.4
  • 81
    • 0033601826 scopus 로고    scopus 로고
    • Tk+/- mouse model for detecting in vivo mutation in an endogenous, autosomal gene
    • Dobrovolsky VN, Casciano DA & Heflich RH (1999) Tk+/- mouse model for detecting in vivo mutation in an endogenous, autosomal gene. Mutat Res, 423: 125-136.
    • (1999) Mutat Res , vol.423 , pp. 125-136
    • Dobrovolsky, V.N.1    Casciano, D.A.2    Heflich, R.H.3
  • 82
    • 16644381712 scopus 로고    scopus 로고
    • Dobrovolsky VN, Shaddock JG & Heflich RH (2005) Analysis of in vivo mutation in the Hprt and Tk genes of mouse lymphocytes. In: Keohavong P & Grant SG eds. Methods in molecular biology. 291. Molecular toxicology protocols. Totowa, New Jersey, Humana Press Inc., pp 133-144.
    • Dobrovolsky VN, Shaddock JG & Heflich RH (2005) Analysis of in vivo mutation in the Hprt and Tk genes of mouse lymphocytes. In: Keohavong P & Grant SG eds. Methods in molecular biology. Vol. 291. Molecular toxicology protocols. Totowa, New Jersey, Humana Press Inc., pp 133-144.
  • 83
    • 0036851242 scopus 로고    scopus 로고
    • Genome dynamics in aging mice
    • Dollé ME & Vijg J (2002) Genome dynamics in aging mice. Genome Res, 12: 1732-1738.
    • (2002) Genome Res , vol.12 , pp. 1732-1738
    • Dollé, M.E.1    Vijg, J.2
  • 84
    • 0030033714 scopus 로고    scopus 로고
    • Evaluation of a plasmid-based transgenic mouse model for detecting in vivo mutations
    • Dollé ME, Martus HJ, Gossen JA, Boerrigter ME & Vijg J (1996) Evaluation of a plasmid-based transgenic mouse model for detecting in vivo mutations. Mutagenesis, 11: 111-118.
    • (1996) Mutagenesis , vol.11 , pp. 111-118
    • Dollé, M.E.1    Martus, H.J.2    Gossen, J.A.3    Boerrigter, M.E.4    Vijg, J.5
  • 86
    • 0034682523 scopus 로고    scopus 로고
    • Distinct spectra of somatic mutations accumulated with age in mouse heart and small intestine
    • Dollé ME, Snyder WK, Gossen JA, Lohman PHM & Vijg J (2000) Distinct spectra of somatic mutations accumulated with age in mouse heart and small intestine. Proc Natl Acad Sci USA, 97: 8403-8408.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 8403-8408
    • Dollé, M.E.1    Snyder, W.K.2    Gossen, J.A.3    Lohman, P.H.M.4    Vijg, J.5
  • 88
    • 0028017876 scopus 로고
    • Sequence spectra of spontaneous lacZ gene mutations in transgenic mouse somatic and germline tissues
    • Douglas GR, Gingerich JD, Gossen JA & Bartlett SA (1994) Sequence spectra of spontaneous lacZ gene mutations in transgenic mouse somatic and germline tissues. Mutagenesis, 9: 451-458.
    • (1994) Mutagenesis , vol.9 , pp. 451-458
    • Douglas, G.R.1    Gingerich, J.D.2    Gossen, J.A.3    Bartlett, S.A.4
  • 89
    • 0029146617 scopus 로고
    • Temporal and molecular characteristics of mutations induced by ethylnitrosourea in germ cells isolated from seminiferous tubules and in spermatozoa of lacZ transgenic mice
    • Douglas GR, Jiao J, Gingerich JD, Gossen JA & Soper LM (1995a) Temporal and molecular characteristics of mutations induced by ethylnitrosourea in germ cells isolated from seminiferous tubules and in spermatozoa of lacZ transgenic mice. Proc Natl Acad Sci USA, 92: 7485-7489.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 7485-7489
    • Douglas, G.R.1    Jiao, J.2    Gingerich, J.D.3    Gossen, J.A.4    Soper, L.M.5
  • 90
    • 0028920498 scopus 로고
    • Evidence for in vivo non-mutagenicity of the carcinogen hydrazine sulfate in target tissues of lacZ transgenic mice
    • Douglas GR, Gingerich JD & Soper LM (1995b) Evidence for in vivo non-mutagenicity of the carcinogen hydrazine sulfate in target tissues of lacZ transgenic mice. Carcinogenesis, 16(4): 801-804.
    • (1995) Carcinogenesis , vol.16 , Issue.4 , pp. 801-804
    • Douglas, G.R.1    Gingerich, J.D.2    Soper, L.M.3
  • 91
    • 0030337742 scopus 로고    scopus 로고
    • Temporal and molecular characteristics of lacZ mutations in somatic tissues of transgenic mice
    • Douglas GR, Jiao J, Gingerich JD, Soper LM & Gossen JA (1996) Temporal and molecular characteristics of lacZ mutations in somatic tissues of transgenic mice. Environ Mol Mutagen, 28: 317-324.
    • (1996) Environ Mol Mutagen , vol.28 , pp. 317-324
    • Douglas, G.R.1    Jiao, J.2    Gingerich, J.D.3    Soper, L.M.4    Gossen, J.A.5
  • 92
    • 0032696947 scopus 로고    scopus 로고
    • Evidence for the lack of base-change and small-deletion mutation induction by trichloroethylene in lacZ transgenic mice
    • Douglas GR, Gingerich JD, Soper LM, Potvin M & Bjarnason S (1999) Evidence for the lack of base-change and small-deletion mutation induction by trichloroethylene in lacZ transgenic mice. Environ Mol Mutagen, 34: 190-194.
    • (1999) Environ Mol Mutagen , vol.34 , pp. 190-194
    • Douglas, G.R.1    Gingerich, J.D.2    Soper, L.M.3    Potvin, M.4    Bjarnason, S.5
  • 93
    • 3242771442 scopus 로고    scopus 로고
    • Inflammatory and genotoxic effects of diesel particles in vitro and in vivo
    • Dybdahl M, Risom L, Bornholdt J, Autrup H, Loft S & Wallin H (2004) Inflammatory and genotoxic effects of diesel particles in vitro and in vivo. Mutat Res, 562(1-2): 119-131.
    • (2004) Mutat Res , vol.562 , Issue.1-2 , pp. 119-131
    • Dybdahl, M.1    Risom, L.2    Bornholdt, J.3    Autrup, H.4    Loft, S.5    Wallin, H.6
  • 95
    • 0029822465 scopus 로고    scopus 로고
    • Species-specific differences in hepatic mutant frequency and mutational spectrum among λ/lacI transgenic rats and mice following exposure to aflatoxin B1
    • Dycaico MJ, Stuart GR, Tobal GM, de Boer JG, Glickman BW & Provost GS (1996) Species-specific differences in hepatic mutant frequency and mutational spectrum among λ/lacI transgenic rats and mice following exposure to aflatoxin B1. Carcinogenesis, 17: 2347-2356.
    • (1996) Carcinogenesis , vol.17 , pp. 2347-2356
    • Dycaico, M.J.1    Stuart, G.R.2    Tobal, G.M.3    de Boer, J.G.4    Glickman, B.W.5    Provost, G.S.6
  • 96
    • 0019195821 scopus 로고
    • Mutagenicity study of Remsen-Fahlberg saccharin and contaminants
    • Eckhardt K, King M-T, Gocke E & Wild D (1980) Mutagenicity study of Remsen-Fahlberg saccharin and contaminants. Toxicol Lett, 7(1): 51-60.
    • (1980) Toxicol Lett , vol.7 , Issue.1 , pp. 51-60
    • Eckhardt, K.1    King, M.-T.2    Gocke, E.3    Wild, D.4
  • 98
    • 0032749587 scopus 로고    scopus 로고
    • Characterization of new transgenic Big Blue® mouse and rat primary fibroblast cell strains for use in molecular toxicology studies
    • Erexson GL, Watson DE & Tindall KR (1999) Characterization of new transgenic Big Blue® mouse and rat primary fibroblast cell strains for use in molecular toxicology studies. Environ Mol Mutagen, 34: 90-96.
    • (1999) Environ Mol Mutagen , vol.34 , pp. 90-96
    • Erexson, G.L.1    Watson, D.E.2    Tindall, K.R.3
  • 99
    • 0242578904 scopus 로고    scopus 로고
    • European Chemicals Bureau , Luxembourg, European Chemicals Bureau, Institute for Health and Consumer Protection, Office for Official Publications of the European Communities, pp
    • European Chemicals Bureau (2002) European Union risk assessment report: o-Anisidine. Luxembourg, European Chemicals Bureau, Institute for Health and Consumer Protection, Office for Official Publications of the European Communities, pp 1-94.
    • (2002) European Union risk assessment report: O-Anisidine , pp. 1-94
  • 100
    • 0017659752 scopus 로고
    • The mammalian spot test (Fellfleckentest) with mice
    • Fahrig R (1977) The mammalian spot test (Fellfleckentest) with mice. Arch Toxicol, 38: 87-98.
    • (1977) Arch Toxicol , vol.38 , pp. 87-98
    • Fahrig, R.1
  • 102
    • 0027731769 scopus 로고
    • Genetic effects of dioxins in the spot test with mice
    • Fahrig R (1993) Genetic effects of dioxins in the spot test with mice. Environ Health Perspect, 101(Suppl. 3): 257-261.
    • (1993) Environ Health Perspect , vol.101 , Issue.SUPPL. 3 , pp. 257-261
    • Fahrig, R.1
  • 103
    • 0030570420 scopus 로고    scopus 로고
    • Co-recombinogenic and anti-mutagenic effects of diethylhexylphthalate, inactiveness of pentachlorophenol in the spot test with mice
    • Fahrig R & Steinkamp-Zucht A (1996) Co-recombinogenic and anti-mutagenic effects of diethylhexylphthalate, inactiveness of pentachlorophenol in the spot test with mice. Mutat Res, 354: 59-67.
    • (1996) Mutat Res , vol.354 , pp. 59-67
    • Fahrig, R.1    Steinkamp-Zucht, A.2
  • 104
    • 0018138536 scopus 로고
    • Sequence of the lacI gene
    • Farabaugh PJ (1978) Sequence of the lacI gene. Nature, 274(5673): 765-769.
    • (1978) Nature , vol.274 , Issue.5673 , pp. 765-769
    • Farabaugh, P.J.1
  • 105
    • 0032565555 scopus 로고    scopus 로고
    • Mutagenicity of the human bladder carcinogen 4-aminobiphenyl to the bladder of Muta™Mouse transgenic mice
    • Fletcher K, Tinwell H & Ashby J (1998) Mutagenicity of the human bladder carcinogen 4-aminobiphenyl to the bladder of Muta™Mouse transgenic mice. Mutat Res, 400: 245-250.
    • (1998) Mutat Res , vol.400 , pp. 245-250
    • Fletcher, K.1    Tinwell, H.2    Ashby, J.3
  • 106
    • 0032725131 scopus 로고    scopus 로고
    • Hepatic gene mutations induced in Big Blue® rats by both the potent rat liver azo-carcinogen 6BT and its reported noncarcinogenic analogue 5BT
    • Fletcher K, Soames AR, Tinwell H, Lefevre PA & Ashby J (1999) Hepatic gene mutations induced in Big Blue® rats by both the potent rat liver azo-carcinogen 6BT and its reported noncarcinogenic analogue 5BT. Environ Mol Mutagen, 34: 148-153.
    • (1999) Environ Mol Mutagen , vol.34 , pp. 148-153
    • Fletcher, K.1    Soames, A.R.2    Tinwell, H.3    Lefevre, P.A.4    Ashby, J.5
  • 107
    • 0004228157 scopus 로고
    • Friedberg EC, Walker GC & Siede W ed , Washington, DC, ASM Press, pp
    • Friedberg EC, Walker GC & Siede W ed (1995) DNA repair and mutagenesis. Washington, DC, ASM Press, pp 1-698.
    • (1995) DNA repair and mutagenesis , pp. 1-698
  • 109
    • 33847156346 scopus 로고    scopus 로고
    • GENE-TOX (1992) N-Propyl-N-nitrosourea. CAS: 816-57-9. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Genetic Toxicology (Mutagenicity) (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?GENETOX).
    • GENE-TOX (1992) N-Propyl-N-nitrosourea. CAS: 816-57-9. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Genetic Toxicology (Mutagenicity) (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?GENETOX).
  • 119
    • 33847116572 scopus 로고    scopus 로고
    • GENE-TOX (1998f) 7,12-Dimethylbenz[a]anthracene. CAS: 57-97-6. Bethesda, Maryland, United States Department of Health and Human Services,
    • GENE-TOX (1998f) 7,12-Dimethylbenz[a]anthracene. CAS: 57-97-6. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Genetic Toxicology (Mutagenicity) (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?GENETOX).
  • 123
    • 33847132718 scopus 로고    scopus 로고
    • GENE-TOX (1998j) N,N-Dipropylnitrosamine. CAS: 621-64-7. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Genetic Toxicology (Mutagenicity) (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?GENETOX).
    • GENE-TOX (1998j) N,N-Dipropylnitrosamine. CAS: 621-64-7. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Genetic Toxicology (Mutagenicity) (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?GENETOX).
  • 127
    • 1842397389 scopus 로고
    • Detection and analysis of UV-induced mutations in mammalian cell DNA using a lambda phage shuttle vector
    • Glazer PM, Sarkar SN & Summers WC (1986) Detection and analysis of UV-induced mutations in mammalian cell DNA using a lambda phage shuttle vector. Proc Natl Acad Sci USA, 83: 1041-1044.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 1041-1044
    • Glazer, P.M.1    Sarkar, S.N.2    Summers, W.C.3
  • 128
    • 0020646751 scopus 로고
    • Mutagenicity studies with the mouse spot test
    • Gocke E, Wild D, Eckhardt K & King MT (1983) Mutagenicity studies with the mouse spot test. Mutat Res, 117: 201-212.
    • (1983) Mutat Res , vol.117 , pp. 201-212
    • Gocke, E.1    Wild, D.2    Eckhardt, K.3    King, M.T.4
  • 129
    • 0032501070 scopus 로고    scopus 로고
    • Hepatic lacI and cII mutation in transgenic (ALIZ) rats treated with dimethylnitrosamine
    • Gollapudi BB, Jackson KM & Stott WT (1998) Hepatic lacI and cII mutation in transgenic (ALIZ) rats treated with dimethylnitrosamine. Mutat Res, 419: 131-135.
    • (1998) Mutat Res , vol.419 , pp. 131-135
    • Gollapudi, B.B.1    Jackson, K.M.2    Stott, W.T.3
  • 130
    • 0029947527 scopus 로고    scopus 로고
    • A novel positive detection system of in vivo mutations in rpsL (strA) transgenic mice
    • Gondo Y, Shioyama Y, Nakao K & Katsuki M (1996) A novel positive detection system of in vivo mutations in rpsL (strA) transgenic mice. Mutat Res, 360: 1-14.
    • (1996) Mutat Res , vol.360 , pp. 1-14
    • Gondo, Y.1    Shioyama, Y.2    Nakao, K.3    Katsuki, M.4
  • 131
    • 0020645067 scopus 로고
    • Gene transfer into mouse embryos: Production of transgenic mice by pronuclear injection
    • Gordon JW & Ruddle FH (1983) Gene transfer into mouse embryos: production of transgenic mice by pronuclear injection. Meth Enzymol, 101: 411-433.
    • (1983) Meth Enzymol , vol.101 , pp. 411-433
    • Gordon, J.W.1    Ruddle, F.H.2
  • 133
    • 0029061266 scopus 로고
    • Overview of mutation assays in transgenic mice for routine testing
    • Gorelick N (1995) Overview of mutation assays in transgenic mice for routine testing. Environ MoI Mutagen, 25: 218-230.
    • (1995) Environ MoI Mutagen , vol.25 , pp. 218-230
    • Gorelick, N.1
  • 134
    • 0028349862 scopus 로고
    • Overview of the workshops on statistical analysis of mutation data from transgenic mice
    • Gorelick NJ & Thompson ED (1994) Overview of the workshops on statistical analysis of mutation data from transgenic mice. Environ Mol Mutagen, 23: 12-16.
    • (1994) Environ Mol Mutagen , vol.23 , pp. 12-16
    • Gorelick, N.J.1    Thompson, E.D.2
  • 135
    • 0028971022 scopus 로고
    • Mutational spectra in the lacI gene in skin from 7,12-dimethylbenz[a]anthracene- treated and untreated transgenic mice
    • Gorelick NJ, Andrews JL, Gu M & Glickman BW (1995) Mutational spectra in the lacI gene in skin from 7,12-dimethylbenz[a]anthracene- treated and untreated transgenic mice. Mol Carcinog, 14: 53-62.
    • (1995) Mol Carcinog , vol.14 , pp. 53-62
    • Gorelick, N.J.1    Andrews, J.L.2    Gu, M.3    Glickman, B.W.4
  • 136
    • 0030989235 scopus 로고    scopus 로고
    • Evaluation of lacI mutation in germ cells and micronuclei in peripheral blood after treatment of male lacI transgenic mice with ethylnitrosourea, isopropylmethane sulfonate or methylmethane sulfonate
    • Gorelick NJ, Andrews JL, Gibson DP, Carr GJ & Aardema MJ (1997) Evaluation of lacI mutation in germ cells and micronuclei in peripheral blood after treatment of male lacI transgenic mice with ethylnitrosourea, isopropylmethane sulfonate or methylmethane sulfonate. Mutat Res, 388: 187-195.
    • (1997) Mutat Res , vol.388 , pp. 187-195
    • Gorelick, N.J.1    Andrews, J.L.2    Gibson, D.P.3    Carr, G.J.4    Aardema, M.J.5
  • 137
    • 0032698083 scopus 로고    scopus 로고
    • Tissue-specific mutant frequencies and mutational spectra in cyclophosphamide-treated lacI transgenic mice
    • Gorelick NJ, Andrews JL, de Boer JG, Young R, Gibson DP & Walker VE (1999) Tissue-specific mutant frequencies and mutational spectra in cyclophosphamide-treated lacI transgenic mice. Environ Mol Mutagen, 34: 154-166.
    • (1999) Environ Mol Mutagen , vol.34 , pp. 154-166
    • Gorelick, N.J.1    Andrews, J.L.2    de Boer, J.G.3    Young, R.4    Gibson, D.P.5    Walker, V.E.6
  • 138
    • 0027389270 scopus 로고
    • Transgenic mice as model systems for studying gene mutations in vivo
    • Gossen J & Vijg J (1993) Transgenic mice as model systems for studying gene mutations in vivo. Trends Genet, 9: 27-31.
    • (1993) Trends Genet , vol.9 , pp. 27-31
    • Gossen, J.1    Vijg, J.2
  • 141
    • 0027535053 scopus 로고
    • Plasmid rescue from transgenic mouse DNA using LacI repressor protein conjugated to magnetic beads
    • Gossen JA, de Leeuw WJF, Molijn AC & Vijg J (1993) Plasmid rescue from transgenic mouse DNA using LacI repressor protein conjugated to magnetic beads. BioTechniques, 14(4): 624-629.
    • (1993) BioTechniques , vol.14 , Issue.4 , pp. 624-629
    • Gossen, J.A.1    de Leeuw, W.J.F.2    Molijn, A.C.3    Vijg, J.4
  • 142
    • 0029098657 scopus 로고
    • Spontaneous and X-ray-induced deletion mutations in a LacZ plasmid-based transgenic mouse model
    • Gossen JA, Martus H-J, Wei JY & Vijg J (1995) Spontaneous and X-ray-induced deletion mutations in a LacZ plasmid-based transgenic mouse model. Mutat Res, 331: 89-97.
    • (1995) Mutat Res , vol.331 , pp. 89-97
    • Gossen, J.A.1    Martus, H.-J.2    Wei, J.Y.3    Vijg, J.4
  • 143
    • 0027468463 scopus 로고
    • Can nongenotoxic carcinogens be detected with the lacI transgenic mouse mutation assay?
    • Gunz D, Shephard SE & Lutz WK (1993) Can nongenotoxic carcinogens be detected with the lacI transgenic mouse mutation assay? Environ Mol Mutagen, 21: 209-211.
    • (1993) Environ Mol Mutagen , vol.21 , pp. 209-211
    • Gunz, D.1    Shephard, S.E.2    Lutz, W.K.3
  • 144
    • 0034103651 scopus 로고    scopus 로고
    • Examination of lacZ mutant induction in the liver and testis of Muta Mouse following injection of halogenated aliphatic hydrocarbons classified as human carcinogens
    • Hachiya N & Motohashi Y (2000) Examination of lacZ mutant induction in the liver and testis of Muta Mouse following injection of halogenated aliphatic hydrocarbons classified as human carcinogens. Ind Health, 38(2): 213-220.
    • (2000) Ind Health , vol.38 , Issue.2 , pp. 213-220
    • Hachiya, N.1    Motohashi, Y.2
  • 146
    • 0032574332 scopus 로고    scopus 로고
    • Comparison between in vivo mutagenicity and carcinogenicity in multiple organs by benzo[a]pyrene in the lacZ transgenic mouse (Muta™Mouse)
    • Hakura A, Tsutsui Y, Sonoda J, Kai J, Imade T, Shimada M, Sugihara Y & Mikami T (1998) Comparison between in vivo mutagenicity and carcinogenicity in multiple organs by benzo[a]pyrene in the lacZ transgenic mouse (Muta™Mouse). Mutat Res, 398: 123-130.
    • (1998) Mutat Res , vol.398 , pp. 123-130
    • Hakura, A.1    Tsutsui, Y.2    Sonoda, J.3    Kai, J.4    Imade, T.5    Shimada, M.6    Sugihara, Y.7    Mikami, T.8
  • 147
    • 0033007949 scopus 로고    scopus 로고
    • Multiple organ mutation in the lacZ transgenic mouse (Muta™Mouse) 6 months after oral treatment (5 days) with benzo[a]pyrene
    • Hakura A, Tsutsui Y, Sonoda J, Mikami T, Tsukidate K, Sagami F & Kerns WD (1999) Multiple organ mutation in the lacZ transgenic mouse (Muta™Mouse) 6 months after oral treatment (5 days) with benzo[a]pyrene. Mutat Res, 426(1): 71-77.
    • (1999) Mutat Res , vol.426 , Issue.1 , pp. 71-77
    • Hakura, A.1    Tsutsui, Y.2    Sonoda, J.3    Mikami, T.4    Tsukidate, K.5    Sagami, F.6    Kerns, W.D.7
  • 148
    • 0034646082 scopus 로고    scopus 로고
    • Comparison of the mutational spectra of the lacZ transgene in four organs of the Muta™Mouse treated with benzo[a]pyrene: Target organ specificity
    • Hakura A, Tsutsui Y, Sonoda J, Tsukidate K, Mikami T & Sagami F (2000) Comparison of the mutational spectra of the lacZ transgene in four organs of the Muta™Mouse treated with benzo[a]pyrene: target organ specificity. Mutat Res, 447(2): 239-247.
    • (2000) Mutat Res , vol.447 , Issue.2 , pp. 239-247
    • Hakura, A.1    Tsutsui, Y.2    Sonoda, J.3    Tsukidate, K.4    Mikami, T.5    Sagami, F.6
  • 149
    • 0034947338 scopus 로고    scopus 로고
    • Spontaneous microdeletions and microinsertions in a transgenic mouse mutation detection system: Analysis of age, tissue, and sequence specificity
    • Halangoda A, Still JG, Hill KA & Sommer SS (2001) Spontaneous microdeletions and microinsertions in a transgenic mouse mutation detection system: analysis of age, tissue, and sequence specificity. Environ Mol Mutagen, 37: 311-323.
    • (2001) Environ Mol Mutagen , vol.37 , pp. 311-323
    • Halangoda, A.1    Still, J.G.2    Hill, K.A.3    Sommer, S.S.4
  • 150
    • 0024389282 scopus 로고
    • Effects of quinoline and 8-hydroxyquinoline on mouse bone marrow erythrocytes as measured by the micronucleus assay
    • Hamoud MA, Ong T, Petersen M & Nath J (1989) Effects of quinoline and 8-hydroxyquinoline on mouse bone marrow erythrocytes as measured by the micronucleus assay. Teratog Carcinog Mutagen, 9: 111-118.
    • (1989) Teratog Carcinog Mutagen , vol.9 , pp. 111-118
    • Hamoud, M.A.1    Ong, T.2    Petersen, M.3    Nath, J.4
  • 153
    • 0032937876 scopus 로고    scopus 로고
    • Spontaneous mutation spectrum at the lambda cII locus in liver, lung, and spleen tissue of Big Blue® transgenic mice
    • Harbach PR, Zimmer DM, Filipunas AL, Mattes WB & Aaron CS (1999) Spontaneous mutation spectrum at the lambda cII locus in liver, lung, and spleen tissue of Big Blue® transgenic mice. Environ Mol Mutagen, 33(2): 132-143.
    • (1999) Environ Mol Mutagen , vol.33 , Issue.2 , pp. 132-143
    • Harbach, P.R.1    Zimmer, D.M.2    Filipunas, A.L.3    Mattes, W.B.4    Aaron, C.S.5
  • 154
    • 0022395719 scopus 로고
    • The mouse spot test: Results with a new cross
    • Hart J (1985) The mouse spot test: results with a new cross. Arch Toxicol, 58(1): 1-4.
    • (1985) Arch Toxicol , vol.58 , Issue.1 , pp. 1-4
    • Hart, J.1
  • 155
    • 2442619404 scopus 로고    scopus 로고
    • Mutations induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in the lacZ and cII genes of Muta™Mouse
    • Hashimoto K, Ohshawa K & Kimura M (2004) Mutations induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in the lacZ and cII genes of Muta™Mouse. Mutat Res, 560(2): 119-131.
    • (2004) Mutat Res , vol.560 , Issue.2 , pp. 119-131
    • Hashimoto, K.1    Ohshawa, K.2    Kimura, M.3
  • 157
    • 0028786875 scopus 로고
    • Differential in vivo mutagenicity of the carcinogen/noncarcinogen pair 2,4- and 2,6-diaminotoluene
    • Hayward JJ, Shane BS, Tindall KR & Cunningham ML (1995) Differential in vivo mutagenicity of the carcinogen/noncarcinogen pair 2,4- and 2,6-diaminotoluene. Carcinogenesis, 16(10): 2429-2433.
    • (1995) Carcinogenesis , vol.16 , Issue.10 , pp. 2429-2433
    • Hayward, J.J.1    Shane, B.S.2    Tindall, K.R.3    Cunningham, M.L.4
  • 158
    • 33847128335 scopus 로고    scopus 로고
    • Health Canada (2004) Detailed review of transgenic rodent mutation assays (draft). Ottawa, Ontario, Health Canada, pp 1-584.
    • Health Canada (2004) Detailed review of transgenic rodent mutation assays (draft). Ottawa, Ontario, Health Canada, pp 1-584.
  • 159
    • 0032940205 scopus 로고    scopus 로고
    • Mutant manifestation: The time factor in somatic mutagenesis
    • Heddle JA (1999) Mutant manifestation: the time factor in somatic mutagenesis. Mutagenesis, 14: 1-3.
    • (1999) Mutagenesis , vol.14 , pp. 1-3
    • Heddle, J.A.1
  • 160
    • 0020511885 scopus 로고
    • The induction of micronuclei as a measure of genotoxicity: A report of the U.S. Environmental Protection Agency GENE-TOX Program
    • Heddle JA, Hite M, Kirkhart B, Mavournin K, MacGregor JT, Newell GW & Salamone MF (1983) The induction of micronuclei as a measure of genotoxicity: A report of the U.S. Environmental Protection Agency GENE-TOX Program. Mutat Res, 123(1): 61-118.
    • (1983) Mutat Res , vol.123 , Issue.1 , pp. 61-118
    • Heddle, J.A.1    Hite, M.2    Kirkhart, B.3    Mavournin, K.4    MacGregor, J.T.5    Newell, G.W.6    Salamone, M.F.7
  • 162
    • 0037255626 scopus 로고    scopus 로고
    • Treatment and sampling protocols for transgenic mutation assays
    • Heddle JA, Martus HJ & Douglas GR (2003) Treatment and sampling protocols for transgenic mutation assays. Environ Mol Mutagen, 41(1): 1-6.
    • (2003) Environ Mol Mutagen , vol.41 , Issue.1 , pp. 1-6
    • Heddle, J.A.1    Martus, H.J.2    Douglas, G.R.3
  • 163
    • 0037427879 scopus 로고    scopus 로고
    • Spontaneous tandem-base mutations (TBM) show dramatic tissue, age, pattern and spectrum specificity
    • Hill KA, Wang J, Farwell KD & Sommer SS (2003) Spontaneous tandem-base mutations (TBM) show dramatic tissue, age, pattern and spectrum specificity. Mutat Res, 534: 173-183.
    • (2003) Mutat Res , vol.534 , pp. 173-183
    • Hill, K.A.1    Wang, J.2    Farwell, K.D.3    Sommer, S.S.4
  • 164
    • 1542618522 scopus 로고    scopus 로고
    • Spontaneous mutation in Big Blue® mice from fetus to old age: Tissue-specific time courses of mutation frequency but similar mutation types
    • Hill KA, Buettner VL, Halangoda A, Kunishige M, Moore SR, Scaringe WA & Sommer SS (2004) Spontaneous mutation in Big Blue® mice from fetus to old age: Tissue-specific time courses of mutation frequency but similar mutation types. Environ Mol Mutagen, 43(2): 110-120.
    • (2004) Environ Mol Mutagen , vol.43 , Issue.2 , pp. 110-120
    • Hill, K.A.1    Buettner, V.L.2    Halangoda, A.3    Kunishige, M.4    Moore, S.R.5    Scaringe, W.A.6    Sommer, S.S.7
  • 166
    • 0037139217 scopus 로고    scopus 로고
    • Dose-dependent increase or decrease of somatic intrachromosomal recombination produced by etoposide
    • Hooker AM, Horne R, Morley AA & Sykes PJ (2002) Dose-dependent increase or decrease of somatic intrachromosomal recombination produced by etoposide. Mutat Res, 500: 117-124.
    • (2002) Mutat Res , vol.500 , pp. 117-124
    • Hooker, A.M.1    Horne, R.2    Morley, A.A.3    Sykes, P.J.4
  • 168
    • 2342600179 scopus 로고    scopus 로고
    • Cancer-associated genes can affect somatic intrachromosomal recombination early in carcinogenesis
    • Hooker AM, Morley AA, Tilley WD & Sykes PJ (2004b) Cancer-associated genes can affect somatic intrachromosomal recombination early in carcinogenesis. Mutat Res, 550: 1-10.
    • (2004) Mutat Res , vol.550 , pp. 1-10
    • Hooker, A.M.1    Morley, A.A.2    Tilley, W.D.3    Sykes, P.J.4
  • 171
    • 0035872422 scopus 로고    scopus 로고
    • Molecular nature of ultraviolet B light-induced deletions in the murine epidermis
    • Horiguchi M, Masumura K, Ikehata H, Ono T, Kanke Y & Nohmi T (2001) Molecular nature of ultraviolet B light-induced deletions in the murine epidermis. Cancer Res, 61: 3913-3918.
    • (2001) Cancer Res , vol.61 , pp. 3913-3918
    • Horiguchi, M.1    Masumura, K.2    Ikehata, H.3    Ono, T.4    Kanke, Y.5    Nohmi, T.6
  • 172
    • 0024559684 scopus 로고
    • Mutational specificities of environmental carcinogens in the lacI gene of Escherichia coli. I. The direct-acting analogue N-nitroso-N-methyl-N-alpha- acetoxymethylamine
    • Horsfall MJ & Glickman BW (1989) Mutational specificities of environmental carcinogens in the lacI gene of Escherichia coli. I. The direct-acting analogue N-nitroso-N-methyl-N-alpha- acetoxymethylamine. Carcinogenesis, 10(5): 817-822.
    • (1989) Carcinogenesis , vol.10 , Issue.5 , pp. 817-822
    • Horsfall, M.J.1    Glickman, B.W.2
  • 174
    • 0031784732 scopus 로고    scopus 로고
    • Mutation studies in lacI transgenic mice after exposure to radiation or cyclophosphamide
    • Hoyes KP, Wadeson PJ, Sharma HL, Hendry JH & Morris ID (1998) Mutation studies in lacI transgenic mice after exposure to radiation or cyclophosphamide. Mutagenesis, 13: 607-612.
    • (1998) Mutagenesis , vol.13 , pp. 607-612
    • Hoyes, K.P.1    Wadeson, P.J.2    Sharma, H.L.3    Hendry, J.H.4    Morris, I.D.5
  • 176
    • 33847174538 scopus 로고    scopus 로고
    • HSDB (2003b) Quinoline. CAS: 91-22-5. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Hazardous Substances Data Bank.
    • HSDB (2003b) Quinoline. CAS: 91-22-5. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Hazardous Substances Data Bank.
  • 178
    • 33847163577 scopus 로고    scopus 로고
    • IARC (1971) 4-Aminobiphenyl. In: Some inorganic substances, chlorinated hydrocarbons, aromatic amines, N-nitroso compounds, and natural products. Lyon, International Agency for Research on Cancer, pp 74-79 (IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Man, 1).
    • IARC (1971) 4-Aminobiphenyl. In: Some inorganic substances, chlorinated hydrocarbons, aromatic amines, N-nitroso compounds, and natural products. Lyon, International Agency for Research on Cancer, pp 74-79 (IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Man, Vol. 1).
  • 179
    • 33847093783 scopus 로고    scopus 로고
    • IARC (1974a) Ethyl methanesulfonate. In: Some anti-thyroid and related substances, nitrofurans and industrial chemicals. Lyon, International Agency for Research on Cancer, pp 245-251 (IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Man, 7).
    • IARC (1974a) Ethyl methanesulfonate. In: Some anti-thyroid and related substances, nitrofurans and industrial chemicals. Lyon, International Agency for Research on Cancer, pp 245-251 (IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Man, Vol. 7).
  • 180
    • 33847140123 scopus 로고    scopus 로고
    • IARC (1974b) Methyl methanesulfonate. In: Some anti-thyroid and related substances, nitrofurans and industrial chemicals. Lyon, International Agency for Research on Cancer, pp 253-260 (IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Man, 7).
    • IARC (1974b) Methyl methanesulfonate. In: Some anti-thyroid and related substances, nitrofurans and industrial chemicals. Lyon, International Agency for Research on Cancer, pp 253-260 (IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Man, Vol. 7).
  • 181
    • 33847165264 scopus 로고    scopus 로고
    • IARC (1974c) N-Methyl-N′-nitro-N- nitrosoguanidine. In: Some aromatic amines, hydrazine and related substances, N-nitroso compounds and miscellaneous alkylating agents. Lyon, International Agency for Research on Cancer, pp 183-195 (IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Man, 4).
    • IARC (1974c) N-Methyl-N′-nitro-N- nitrosoguanidine. In: Some aromatic amines, hydrazine and related substances, N-nitroso compounds and miscellaneous alkylating agents. Lyon, International Agency for Research on Cancer, pp 183-195 (IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Man, Vol. 4).
  • 182
    • 33847155020 scopus 로고    scopus 로고
    • IARC (1974d) Urethane. In: Some anti-thyroid and related substances, nitrofurans and industrial chemicals. Lyon, International Agency for Research on Cancer, pp 111-140 (IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Man, 7).
    • IARC (1974d) Urethane. In: Some anti-thyroid and related substances, nitrofurans and industrial chemicals. Lyon, International Agency for Research on Cancer, pp 111-140 (IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Man, Vol. 7).
  • 183
    • 0017242103 scopus 로고    scopus 로고
    • IARC (1976) Mitomycin C. In: Some naturally occurring substances. Lyon, International Agency for Research on Cancer, pp 171-179 (IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Man, 10).
    • IARC (1976) Mitomycin C. In: Some naturally occurring substances. Lyon, International Agency for Research on Cancer, pp 171-179 (IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Man, Vol. 10).
  • 184
    • 33847115707 scopus 로고    scopus 로고
    • IARC (1977a) Asbestos. Lyon, International Agency for Research on Cancer, pp 1-106 (IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Man, 14).
    • IARC (1977a) Asbestos. Lyon, International Agency for Research on Cancer, pp 1-106 (IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Man, Vol. 14).
  • 185
    • 33847102226 scopus 로고    scopus 로고
    • IARC (1977b) Phenobarbital and phenobarbital sodium. In: Some miscellaneous pharmaceutical substances. Lyon, International Agency for Research on Cancer, pp 157-181 (IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Man, 13).
    • IARC (1977b) Phenobarbital and phenobarbital sodium. In: Some miscellaneous pharmaceutical substances. Lyon, International Agency for Research on Cancer, pp 157-181 (IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Man, Vol. 13).
  • 186
    • 33847103091 scopus 로고
    • IARC , nitroso compounds. Lyon, International Agency for Research on Cancer, pp, IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans
    • IARC (1978a) N-Nitrosodiethylamine. In: Some N-nitroso compounds. Lyon, International Agency for Research on Cancer, pp 89-106 (IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, Vol. 17).
    • (1978) N-Nitrosodiethylamine. In: Some N , vol.17 , pp. 89-106
  • 187
    • 0017965713 scopus 로고
    • IARC , nitroso compounds. Lyon, International Agency for Research on Cancer, pp, IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans
    • IARC (1978b) N-Nitrosodimethylamine. In: Some N-nitroso compounds. Lyon, International Agency for Research on Cancer, pp 125-175 (IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, Vol. 17).
    • (1978) N-Nitrosodimethylamine. In: Some N , vol.17 , pp. 125-175
  • 188
    • 0017967914 scopus 로고
    • IARC , nitroso compounds. Lyon, International Agency for Research on Cancer, pp, IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans
    • IARC (1978c) N-Nitroso-N-ethylurea. In: Some N-nitroso compounds. Lyon, International Agency for Research on Cancer, pp 191-215 (IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, Vol. 17).
    • (1978) N-Nitroso-N-ethylurea. In: Some N , vol.17 , pp. 191-215
  • 189
    • 0017963671 scopus 로고
    • IARC , nitroso compounds. Lyon, International Agency for Research on Cancer, pp, IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans
    • IARC (1978d) N-Nitroso-N-methylurea. In: Some N-nitroso compounds. Lyon, International Agency for Research on Cancer, pp 227-255 (IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, Vol. 17).
    • (1978) N-Nitroso-N-methylurea. In: Some N , vol.17 , pp. 227-255
  • 190
    • 0018526111 scopus 로고    scopus 로고
    • IARC (1979) 1,2-Dichloroethane. In: Some halogenated hydrocarbons. Lyon, International Agency for Research on Cancer, pp 429-448 (IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, 20).
    • IARC (1979) 1,2-Dichloroethane. In: Some halogenated hydrocarbons. Lyon, International Agency for Research on Cancer, pp 429-448 (IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, Vol. 20).
  • 191
    • 33847132717 scopus 로고    scopus 로고
    • IARC (1980) Saccharin. In: Some non-nutritive sweetening agents. Lyon, International Agency for Research on Cancer, pp 132-170 (IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, 22).
    • IARC (1980) Saccharin. In: Some non-nutritive sweetening agents. Lyon, International Agency for Research on Cancer, pp 132-170 (IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, Vol. 22).
  • 192
    • 0019563822 scopus 로고    scopus 로고
    • IARC (1981a) Chlorambucil. In: Some antineoplastic and immunosuppressive agents. Lyon, International Agency for Research on Cancer, pp 115-136 (IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, 26).
    • IARC (1981a) Chlorambucil. In: Some antineoplastic and immunosuppressive agents. Lyon, International Agency for Research on Cancer, pp 115-136 (IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, Vol. 26).
  • 193
    • 0019562725 scopus 로고    scopus 로고
    • IARC (1981b) Cyclophosphamide. In: Some antineoplastic and immunosuppressive agents. Lyon, International Agency for Research on Cancer, pp 165-202 (IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, 26).
    • IARC (1981b) Cyclophosphamide. In: Some antineoplastic and immunosuppressive agents. Lyon, International Agency for Research on Cancer, pp 165-202 (IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, Vol. 26).
  • 194
    • 0019562586 scopus 로고    scopus 로고
    • IARC (1981c) Procarbazine hydrochloride. In: Some antineoplastic and immunosuppressive agents. Lyon, International Agency for Research on Cancer, pp 311-339 (IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, 26).
    • IARC (1981c) Procarbazine hydrochloride. In: Some antineoplastic and immunosuppressive agents. Lyon, International Agency for Research on Cancer, pp 311-339 (IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, Vol. 26).
  • 195
    • 33847137247 scopus 로고    scopus 로고
    • IARC (1982) Benzene. In: Some industrial chemicals and dyestuffs. Lyon, International Agency for Research on Cancer, pp 94-148 (IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, 29).
    • IARC (1982) Benzene. In: Some industrial chemicals and dyestuffs. Lyon, International Agency for Research on Cancer, pp 94-148 (IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, Vol. 29).
  • 196
    • 0020791589 scopus 로고    scopus 로고
    • IARC (1983) Agaritine (L-glutamic acid-5-[2-(4-hydroxymethyl)- phenylhydrazide]). In: Some food additives, feed additives and naturally occurring substances. Lyon, International Agency for Research on Cancer, pp 63-69 (IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, 31).
    • IARC (1983) Agaritine (L-glutamic acid-5-[2-(4-hydroxymethyl)- phenylhydrazide]). In: Some food additives, feed additives and naturally occurring substances. Lyon, International Agency for Research on Cancer, pp 63-69 (IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, Vol. 31).
  • 197
    • 0022126170 scopus 로고    scopus 로고
    • IARC (1985) 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). In: Tobacco habits other than smoking. Lyon, International Agency for Research on Cancer, pp 209-223 (IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, 37).
    • IARC (1985) 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). In: Tobacco habits other than smoking. Lyon, International Agency for Research on Cancer, pp 209-223 (IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, Vol. 37).
  • 198
    • 33847112427 scopus 로고    scopus 로고
    • IARC (1987a) 4,4′-Methylene bis(2-methylaniline) (Group 2B). In: Overall evaluations of carcinogenicity: an updating of IARC Monographs 1 to 42. Lyon, International Agency for Research on Cancer, pp 248-250 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Suppl. 7).
    • IARC (1987a) 4,4′-Methylene bis(2-methylaniline) (Group 2B). In: Overall evaluations of carcinogenicity: an updating of IARC Monographs Volumes 1 to 42. Lyon, International Agency for Research on Cancer, pp 248-250 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Suppl. 7).
  • 199
    • 33847169833 scopus 로고    scopus 로고
    • IARC (1987b) Asbestos (Group 1). In: Overall evaluations of carcinogenicity: an updating of IARC Monographs 1 to 42. Lyon, International Agency, for Research on Cancer, pp 106-116 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Suppl. 7).
    • IARC (1987b) Asbestos (Group 1). In: Overall evaluations of carcinogenicity: an updating of IARC Monographs Volumes 1 to 42. Lyon, International Agency, for Research on Cancer, pp 106-116 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Suppl. 7).
  • 200
    • 33847111128 scopus 로고    scopus 로고
    • IARC (1987c) Asbestos. In: Genetic and related effects: an updating of selected IARC monographs from 1 to 42. Lyon, International Agency for Research on Cancer, pp 77-80 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Suppl. 6).
    • IARC (1987c) Asbestos. In: Genetic and related effects: an updating of selected IARC monographs from volumes 1 to 42. Lyon, International Agency for Research on Cancer, pp 77-80 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Suppl. 6).
  • 201
    • 33847170268 scopus 로고    scopus 로고
    • IARC (1987d) Chlorambucil (Group 1). In: Overall evaluations of carcinogenicity: an updating of IARC Monographs 1 to 42. Lyon, International Agency for Research on Cancer, pp 144-145 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Suppl. 7).
    • IARC (1987d) Chlorambucil (Group 1). In: Overall evaluations of carcinogenicity: an updating of IARC Monographs Volumes 1 to 42. Lyon, International Agency for Research on Cancer, pp 144-145 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Suppl. 7).
  • 202
    • 33847127395 scopus 로고    scopus 로고
    • IARC (1987e) Cyclophosphamide (Group 1). In: Overall evaluations of carcinogenicity: An updating of IARC Monographs 1 to 42. Lyon, International Agency for Research on Cancer, pp 182-184 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Suppl. 7).
    • IARC (1987e) Cyclophosphamide (Group 1). In: Overall evaluations of carcinogenicity: An updating of IARC Monographs Volumes 1 to 42. Lyon, International Agency for Research on Cancer, pp 182-184 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Suppl. 7).
  • 203
    • 33847092915 scopus 로고    scopus 로고
    • IARC (1987f) N-Methyl-N′-nitro-N- nitrosoguanidine. In: Genetic and related effects: an updating of selected IARC monographs from 1 to 42. Lyon, International Agency for Research on Cancer, 394-398 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Suppl. 6).
    • IARC (1987f) N-Methyl-N′-nitro-N- nitrosoguanidine. In: Genetic and related effects: an updating of selected IARC monographs from volumes 1 to 42. Lyon, International Agency for Research on Cancer, 394-398 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Suppl. 6).
  • 204
    • 33847102225 scopus 로고    scopus 로고
    • IARC (1987g) Phenobarbital (Group 2b). In: Overall evaluations of carcinogenicity: an updating of IARC Monographs 1 to 42. Lyon, International Agency for Research on Cancer, pp 313-316 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Suppl. 7).
    • IARC (1987g) Phenobarbital (Group 2b). In: Overall evaluations of carcinogenicity: an updating of IARC Monographs Volumes 1 to 42. Lyon, International Agency for Research on Cancer, pp 313-316 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Suppl. 7).
  • 205
    • 33847127396 scopus 로고    scopus 로고
    • IARC (1987h) Phenobarbital. In: Genetic and related effects: an updating of selected IARC monographs from 1 to 42. Lyon, International Agency for Research on Cancer, pp 455-458 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Suppl. 6).
    • IARC (1987h) Phenobarbital. In: Genetic and related effects: an updating of selected IARC monographs from volumes 1 to 42. Lyon, International Agency for Research on Cancer, pp 455-458 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Suppl. 6).
  • 206
    • 33847108909 scopus 로고    scopus 로고
    • IARC (1987i) Procarbazine hydrochloride (Group 2A). In: Overall evaluations of carcinogenicity: an updating of IARC Monographs 1 to 42. Lyon, International Agency for Research on Cancer, pp 327-328 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Suppl. 7).
    • IARC (1987i) Procarbazine hydrochloride (Group 2A). In: Overall evaluations of carcinogenicity: an updating of IARC Monographs Volumes 1 to 42. Lyon, International Agency for Research on Cancer, pp 327-328 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Suppl. 7).
  • 207
    • 33847126112 scopus 로고    scopus 로고
    • IARC (1987j) Saccharin (Group B). In: Overall evaluations of carcinogenicity: an updating of IARC Monographs 1 to 42. Lyon, International Agency for Research on Cancer, pp 334-339 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Suppl. 7).
    • IARC (1987j) Saccharin (Group B). In: Overall evaluations of carcinogenicity: an updating of IARC Monographs Volumes 1 to 42. Lyon, International Agency for Research on Cancer, pp 334-339 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Suppl. 7).
  • 208
    • 0027501524 scopus 로고    scopus 로고
    • IARC (1993a) Aflatoxins. In: Some naturally occurring substances: food items and constituents, heterocyclic aromatic amines and mycotoxins. Lyon, International Agency for Research on Cancer, pp 245-395 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, 56).
    • IARC (1993a) Aflatoxins. In: Some naturally occurring substances: food items and constituents, heterocyclic aromatic amines and mycotoxins. Lyon, International Agency for Research on Cancer, pp 245-395 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 56).
  • 209
    • 0027422314 scopus 로고    scopus 로고
    • IARC (1993b) IQ (2-Amino-3-methylimidazo[4,5-f]quinoline). In: Some naturally occurring substances: food items and constituents, heterocyclic aromatic amines and mycotoxins. Lyon, International Agency for Research on Cancer, pp 165-195 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, 56).
    • IARC (1993b) IQ (2-Amino-3-methylimidazo[4,5-f]quinoline). In: Some naturally occurring substances: food items and constituents, heterocyclic aromatic amines and mycotoxins. Lyon, International Agency for Research on Cancer, pp 165-195 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 56).
  • 210
    • 0027527493 scopus 로고    scopus 로고
    • IARC (1993c) MeIQ (2-Amino-3,4-dimethylinidazo[4,5-f]quinoline). In: Some naturally occurring substances: food items and constituents, heterocyclic aromatic amines and mycotoxins. Lyon, International Agency for Research on Cancer, pp 197-210 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, 56).
    • IARC (1993c) MeIQ (2-Amino-3,4-dimethylinidazo[4,5-f]quinoline). In: Some naturally occurring substances: food items and constituents, heterocyclic aromatic amines and mycotoxins. Lyon, International Agency for Research on Cancer, pp 197-210 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 56).
  • 211
    • 0027370835 scopus 로고    scopus 로고
    • IARC (1993d) PhIP (2-Amino-1-methyl-6-phenylimidazo[4,5-b] pyridine). In: Some naturally occurring substances: food items and constituents, heterocyclic aromatic amines and mycotoxins. Lyon, International Agency for Research on Cancer, pp 229-242 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, 56).
    • IARC (1993d) PhIP (2-Amino-1-methyl-6-phenylimidazo[4,5-b] pyridine). In: Some naturally occurring substances: food items and constituents, heterocyclic aromatic amines and mycotoxins. Lyon, International Agency for Research on Cancer, pp 229-242 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 56).
  • 212
    • 0027445387 scopus 로고    scopus 로고
    • IARC (1993e) MeIQx (2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline) . In: Some naturally occurring substances: food items and constituents, heterocyclic aromatic amines and mycotoxins. Lyon, International Agency for Research on Cancer, pp 211-228 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, 56).
    • IARC (1993e) MeIQx (2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline) . In: Some naturally occurring substances: food items and constituents, heterocyclic aromatic amines and mycotoxins. Lyon, International Agency for Research on Cancer, pp 211-228 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 56).
  • 213
    • 0028589882 scopus 로고    scopus 로고
    • IARC (1994a) Acrylamide. In: Some industrial chemicals. Lyon, International Agency for Research on Cancer, pp 389-433 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, 60).
    • IARC (1994a) Acrylamide. In: Some industrial chemicals. Lyon, International Agency for Research on Cancer, pp 389-433 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 60).
  • 214
    • 0028609108 scopus 로고    scopus 로고
    • IARC (1994b) Ethylene oxide. In: Some industrial chemicals. Lyon, International Agency for Research on Cancer, pp 73-160 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, 60).
    • IARC (1994b) Ethylene oxide. In: Some industrial chemicals. Lyon, International Agency for Research on Cancer, pp 73-160 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 60).
  • 215
    • 0030321284 scopus 로고    scopus 로고
    • IARC (1996) Tamoxifen. In: Some pharmaceutical drugs. Lyon, International Agency for Research on Cancer, pp 253-365 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, 66).
    • IARC (1996) Tamoxifen. In: Some pharmaceutical drugs. Lyon, International Agency for Research on Cancer, pp 253-365 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 66).
  • 216
    • 33847129601 scopus 로고    scopus 로고
    • IARC (1997) Polychlorinated dibenzo-para-dioxins. In: Polychlorinated dibenzo-paradioxins and polychlorinated dibenzofurans. Lyon, International Agency for Research on Cancer, pp 194-219 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, 69).
    • IARC (1997) Polychlorinated dibenzo-para-dioxins. In: Polychlorinated dibenzo-paradioxins and polychlorinated dibenzofurans. Lyon, International Agency for Research on Cancer, pp 194-219 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 69).
  • 217
    • 0032727767 scopus 로고    scopus 로고
    • IARC (1999a) 1,3-Butadiene. In: Re-evaluation of some organic chemicals, hydrazine and hydrogen peroxide (part one). Lyon, International Agency for Research on Cancer, pp 109-225 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, 71).
    • IARC (1999a) 1,3-Butadiene. In: Re-evaluation of some organic chemicals, hydrazine and hydrogen peroxide (part one). Lyon, International Agency for Research on Cancer, pp 109-225 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 71).
  • 218
    • 0032698668 scopus 로고    scopus 로고
    • IARC (1999b) Methyl methanesulfonate. In: Re-evaluation of some organic chemicals, hydrazine and hydrogen peroxide (part three A). Lyon, International Agency for Research on Cancer, pp 1059-1078 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, 71).
    • IARC (1999b) Methyl methanesulfonate. In: Re-evaluation of some organic chemicals, hydrazine and hydrogen peroxide (part three A). Lyon, International Agency for Research on Cancer, pp 1059-1078 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 71).
  • 219
    • 33847138981 scopus 로고    scopus 로고
    • IARC (1999c) Saccharin and its salts. In: Some chemicals that cause tumours of the kidney or urinary bladder in rodents and some other substances. Lyon, International Agency for Research on Cancer, pp 517-624 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, 73).
    • IARC (1999c) Saccharin and its salts. In: Some chemicals that cause tumours of the kidney or urinary bladder in rodents and some other substances. Lyon, International Agency for Research on Cancer, pp 517-624 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 73).
  • 220
    • 0032716973 scopus 로고    scopus 로고
    • IARC (1999d) Ethylene dibromide. In: Re-evaluation of some organic chemicals, hydrazine and hydrogen peroxide (part two). Lyon, International Agency for Research on Cancer, p 641 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, 71).
    • IARC (1999d) Ethylene dibromide. In: Re-evaluation of some organic chemicals, hydrazine and hydrogen peroxide (part two). Lyon, International Agency for Research on Cancer, p 641 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 71).
  • 221
    • 0032722173 scopus 로고    scopus 로고
    • IARC (1999e) 1,2-Dibromo-3-chloropropane. In: Re-evaluation of some organic chemicals, hydrazine and hydrogen peroxide (part two). Lyon, International Agency for Research on Cancer, p 479 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, 71).
    • IARC (1999e) 1,2-Dibromo-3-chloropropane. In: Re-evaluation of some organic chemicals, hydrazine and hydrogen peroxide (part two). Lyon, International Agency for Research on Cancer, p 479 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 71).
  • 222
    • 0032696558 scopus 로고    scopus 로고
    • IARC (1999f) 1,2-Dichloroethane. In: Re-evaluation of some organic chemicals, hydrazine and hydrogen peroxide (part two). Lyon, International Agency for Research on Cancer, pp 501-529 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, 71).
    • IARC (1999f) 1,2-Dichloroethane. In: Re-evaluation of some organic chemicals, hydrazine and hydrogen peroxide (part two). Lyon, International Agency for Research on Cancer, pp 501-529 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 71).
  • 223
    • 33746012759 scopus 로고    scopus 로고
    • IARC (2001) Chlordane and heptachlor. In: Some thyrotropic agents. Lyon, International Agency for Research on Cancer, pp 411-493 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, 79).
    • IARC (2001) Chlordane and heptachlor. In: Some thyrotropic agents. Lyon, International Agency for Research on Cancer, pp 411-493 (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 79).
  • 224
    • 0028904990 scopus 로고
    • A novel assay for illegitimate recombination in Escherichia coli: Simulation of lambda bio transducing phage formation by ultra-violet light and its independence from RecA function
    • Ikeda H, Shimizu T, Ukita T & Kumagai M (1995) A novel assay for illegitimate recombination in Escherichia coli: simulation of lambda bio transducing phage formation by ultra-violet light and its independence from RecA function. Adv Biophys, 31:197-208.
    • (1995) Adv Biophys , vol.31 , pp. 197-208
    • Ikeda, H.1    Shimizu, T.2    Ukita, T.3    Kumagai, M.4
  • 225
    • 33847152555 scopus 로고    scopus 로고
    • IPCS (1993) Benzene. Geneva, Wortd Health Organization, International Programme on Chemical Safety, pp 1-156 (Environmental Health Criteria 150).
    • IPCS (1993) Benzene. Geneva, Wortd Health Organization, International Programme on Chemical Safety, pp 1-156 (Environmental Health Criteria 150).
  • 226
    • 33847167037 scopus 로고    scopus 로고
    • IPCS (1995a) Methyl bromide. Geneva, World Health Organization, International Programme on Chemical Safety, pp 1-324 (Environmental Health Criteria 166).
    • IPCS (1995a) Methyl bromide. Geneva, World Health Organization, International Programme on Chemical Safety, pp 1-324 (Environmental Health Criteria 166).
  • 227
    • 33847164004 scopus 로고    scopus 로고
    • IPCS (1995b) Tris(2,3-dibromopropyl) phosphate and bis(2,3-dibromopropyl) phosphate. Geneva, World Health Organization, International Programme on Chemical Safety, pp 1-129 (Environmental Health Criteria 173).
    • IPCS (1995b) Tris(2,3-dibromopropyl) phosphate and bis(2,3-dibromopropyl) phosphate. Geneva, World Health Organization, International Programme on Chemical Safety, pp 1-129 (Environmental Health Criteria 173).
  • 228
    • 33847110160 scopus 로고    scopus 로고
    • IPCS (1998a) Limonene. Geneva, World Health Organization, International Programme on Chemical Safety, pp 1-32 (Concise International Chemical Assessment Document No. 5).
    • IPCS (1998a) Limonene. Geneva, World Health Organization, International Programme on Chemical Safety, pp 1-32 (Concise International Chemical Assessment Document No. 5).
  • 229
    • 33847118936 scopus 로고    scopus 로고
    • IPCS (1998b) Selected non-heterocyclic polycyclic aromatic hydrocarbons. Geneva, World Health Organization, International Programme on Chemical Safety, pp 1-883 (Environmental Health Criteria 202).
    • IPCS (1998b) Selected non-heterocyclic polycyclic aromatic hydrocarbons. Geneva, World Health Organization, International Programme on Chemical Safety, pp 1-883 (Environmental Health Criteria 202).
  • 230
    • 33847136337 scopus 로고    scopus 로고
    • IRIS (2002a) Bromomethane. CAS: 74-83-9. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Integrated Risk Information System (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?IRIS).
    • IRIS (2002a) Bromomethane. CAS: 74-83-9. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Integrated Risk Information System (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?IRIS).
  • 231
    • 33847095019 scopus 로고    scopus 로고
    • IRIS (2002b) N-Nitrosodi-n-propylamine. CAS: 621-64-7. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Integrated Risk Information System (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?IRIS).
    • IRIS (2002b) N-Nitrosodi-n-propylamine. CAS: 621-64-7. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Integrated Risk Information System (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?IRIS).
  • 232
    • 33847134758 scopus 로고    scopus 로고
    • IRIS (2002c) Quinoline. CAS: 91-22-5. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Integrated Risk Information System (http://toxnet.nlm.nih. gov/cgi-bin/sis/htmlgen?IRIS).
    • IRIS (2002c) Quinoline. CAS: 91-22-5. Bethesda, Maryland, United States Department of Health and Human Services, National Institutes of Health, National Library of Medicine, Integrated Risk Information System (http://toxnet.nlm.nih. gov/cgi-bin/sis/htmlgen?IRIS).
  • 233
    • 0017722987 scopus 로고
    • Chromosome tests with 134 compounds on Chinese hamster cells in vitro - a screening for chemical carcinogens
    • Ishidate M & Odashima S (1977) Chromosome tests with 134 compounds on Chinese hamster cells in vitro - a screening for chemical carcinogens. Mutat Res, 48(3-4): 337-354.
    • (1977) Mutat Res , vol.48 , Issue.3-4 , pp. 337-354
    • Ishidate, M.1    Odashima, S.2
  • 234
    • 0030995757 scopus 로고    scopus 로고
    • Germ cell mutagenesis in lacZ transgenic mice treated with methyl methanesulfonate
    • Itoh S, Miura M & Shimada H (1997) Germ cell mutagenesis in lacZ transgenic mice treated with methyl methanesulfonate. Mutat Res, 388: 223-228.
    • (1997) Mutat Res , vol.388 , pp. 223-228
    • Itoh, S.1    Miura, M.2    Shimada, H.3
  • 236
    • 0034702348 scopus 로고    scopus 로고
    • In vivo genotoxicity of 2-amino-3,8-dimethylimidazo[4,5- f]quinoline in lacI transgenic (Big Blue®) mice
    • Itoh T, Suzuki T, Nishikawa A, Furukawa F, Takahashi M, Xue W, Sofuni T & Hayashi M (2000) In vivo genotoxicity of 2-amino-3,8-dimethylimidazo[4,5- f]quinoline in lacI transgenic (Big Blue®) mice. Mutat Res, 468: 19-25.
    • (2000) Mutat Res , vol.468 , pp. 19-25
    • Itoh, T.1    Suzuki, T.2    Nishikawa, A.3    Furukawa, F.4    Takahashi, M.5    Xue, W.6    Sofuni, T.7    Hayashi, M.8
  • 237
    • 0042388513 scopus 로고    scopus 로고
    • Regional mutagenicity of heterocyclic amines in the intestine: Mutation analysis of the cII gene in lambda/lacZ transgenic mice
    • Itoh T, Kuwahara T, Suzuki T, Hayashi M & Ohnishi Y (2003) Regional mutagenicity of heterocyclic amines in the intestine: mutation analysis of the cII gene in lambda/lacZ transgenic mice. Mutat Res, 539(1-2): 99-108.
    • (2003) Mutat Res , vol.539 , Issue.1-2 , pp. 99-108
    • Itoh, T.1    Kuwahara, T.2    Suzuki, T.3    Hayashi, M.4    Ohnishi, Y.5
  • 238
    • 0029810641 scopus 로고    scopus 로고
    • Analysis of genetic instability during mammary tumor progression using a novel selection-based assay for in vivo mutations in a bacteriophage λ transgene target
    • Jakubczak JL, Merlino G, French JE, Muller WJ, Paul B, Adhya S & Garges S (1996) Analysis of genetic instability during mammary tumor progression using a novel selection-based assay for in vivo mutations in a bacteriophage λ transgene target. Proc Natl Acad Sci USA, 93: 9073-9078.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 9073-9078
    • Jakubczak, J.L.1    Merlino, G.2    French, J.E.3    Muller, W.J.4    Paul, B.5    Adhya, S.6    Garges, S.7
  • 239
    • 2342531228 scopus 로고    scopus 로고
    • Organ variation in the mutagenicity of ethylnitrosourea in Muta™Mouse: Results of the collaborative study on the transgenic mutation assay by JEMS/MMS
    • JEMS/MMS
    • JEMS/MMS (1996) Organ variation in the mutagenicity of ethylnitrosourea in Muta™Mouse: results of the collaborative study on the transgenic mutation assay by JEMS/MMS. Environ Mol Mutagen, 28: 363-375.
    • (1996) Environ Mol Mutagen , vol.28 , pp. 363-375
  • 240
    • 0017048167 scopus 로고
    • Dose response at low doses of X-irradiation and MMS on the induction of micronuclei in mouse erythroblasts
    • Jenssen D & Ramel C (1976) Dose response at low doses of X-irradiation and MMS on the induction of micronuclei in mouse erythroblasts. Mutat Res, 41: 311-319.
    • (1976) Mutat Res , vol.41 , pp. 311-319
    • Jenssen, D.1    Ramel, C.2
  • 241
    • 0018818908 scopus 로고
    • The micronucleus test as part of a short-term mutagenicity test program for the prediction of carcinogenicity evaluated by 143 agents tested
    • Jenssen D & Ramel C (1980) The micronucleus test as part of a short-term mutagenicity test program for the prediction of carcinogenicity evaluated by 143 agents tested. Mutat Res, 75: 191-202.
    • (1980) Mutat Res , vol.75 , pp. 191-202
    • Jenssen, D.1    Ramel, C.2
  • 242
  • 243
    • 0031001715 scopus 로고    scopus 로고
    • Mutations induced in male germ cells after treatment of transgenic mice with ethylnitrosourea
    • Katoh M, Horiya N & Valdivia RPA (1997) Mutations induced in male germ cells after treatment of transgenic mice with ethylnitrosourea. Mutat Res, 388: 229-237.
    • (1997) Mutat Res , vol.388 , pp. 229-237
    • Katoh, M.1    Horiya, N.2    Valdivia, R.P.A.3
  • 244
    • 0019349675 scopus 로고
    • Micronucleus test and bone-marrow chromosome analysis: A comparison of 2 methods in vivo for evaluating chemically induced chromosomal alterations
    • Kliesch U, Danford N & Adler I-D (1981) Micronucleus test and bone-marrow chromosome analysis: a comparison of 2 methods in vivo for evaluating chemically induced chromosomal alterations. Mutat Res, 80(2): 321-332.
    • (1981) Mutat Res , vol.80 , Issue.2 , pp. 321-332
    • Kliesch, U.1    Danford, N.2    Adler, I.-D.3
  • 246
    • 0035810284 scopus 로고    scopus 로고
    • Mutation spectrum of o-aminoazotoluene in the cII gene of lambda/lacZ transgenic mice (Muta™Mouse)
    • Kohara A, Suzuki T, Honma M, Hirano N, Ohsawa K, Ohwada T & Hayashi M (2001) Mutation spectrum of o-aminoazotoluene in the cII gene of lambda/lacZ transgenic mice (Muta™Mouse). Mutat Res, 491(1-2): 211-220.
    • (2001) Mutat Res , vol.491 , Issue.1-2 , pp. 211-220
    • Kohara, A.1    Suzuki, T.2    Honma, M.3    Hirano, N.4    Ohsawa, K.5    Ohwada, T.6    Hayashi, M.7
  • 247
    • 0037170659 scopus 로고    scopus 로고
    • Mutagenicity of aristolochic acid in the λ/lacZ transgenic mouse (Muta™Mouse)
    • Kohara A, Suzuki T, Honma M, Ohwada T & Hayashi M (2002a) Mutagenicity of aristolochic acid in the λ/lacZ transgenic mouse (Muta™Mouse). Mutat Res, 515(1-2): 63-72.
    • (2002) Mutat Res , vol.515 , Issue.1-2 , pp. 63-72
    • Kohara, A.1    Suzuki, T.2    Honma, M.3    Ohwada, T.4    Hayashi, M.5
  • 248
    • 0037170682 scopus 로고    scopus 로고
    • Dinitropyrenes induce gene mutations in multiple organs of the λ/lacZ transgenic mouse (Muta™Mouse)
    • Kohara A, Suzuki T, Honma M, Oomori T, Ohwada T & Hayashi M (2002b) Dinitropyrenes induce gene mutations in multiple organs of the λ/lacZ transgenic mouse (Muta™Mouse). Mutat Res, 515(1-2): 73-83.
    • (2002) Mutat Res , vol.515 , Issue.1-2 , pp. 73-83
    • Kohara, A.1    Suzuki, T.2    Honma, M.3    Oomori, T.4    Ohwada, T.5    Hayashi, M.6
  • 252
    • 0033061415 scopus 로고    scopus 로고
    • Mutagenesis induced by benzo[a]pyrene in lacZ mouse mammary and oral tissues: Comparisons with mutagenesis in other organs and relationships to previous carcinogenicity assays
    • Kosinska W, von Pressentin MdM & Guttenplan JB (1999) Mutagenesis induced by benzo[a]pyrene in lacZ mouse mammary and oral tissues: comparisons with mutagenesis in other organs and relationships to previous carcinogenicity assays. Carcinogenesis, 20(6): 1103-1106.
    • (1999) Carcinogenesis , vol.20 , Issue.6 , pp. 1103-1106
    • Kosinska, W.1    von Pressentin, M.M.2    Guttenplan, J.B.3
  • 253
    • 0030949309 scopus 로고    scopus 로고
    • Somatic and germ cell mutagenesis in lambda lacZ transgenic mice treated with acrylamide or ethylnitrosourea
    • Krebs O & Favor J (1997) Somatic and germ cell mutagenesis in lambda lacZ transgenic mice treated with acrylamide or ethylnitrosourea. Mutat Res, 388: 239-248.
    • (1997) Mutat Res , vol.388 , pp. 239-248
    • Krebs, O.1    Favor, J.2
  • 256
    • 0031026612 scopus 로고    scopus 로고
    • Mutagenicity of the potent rat hepatocarcinogen 6BT to the liver of transgenic (lacI) rats: Consideration of a reduced mutation assay protocol
    • Lefevre PA, Tinwell H & Ashby J (1997) Mutagenicity of the potent rat hepatocarcinogen 6BT to the liver of transgenic (lacI) rats: consideration of a reduced mutation assay protocol. Mutagenesis, 12: 45-47.
    • (1997) Mutagenesis , vol.12 , pp. 45-47
    • Lefevre, P.A.1    Tinwell, H.2    Ashby, J.3
  • 257
    • 0037039463 scopus 로고    scopus 로고
    • UV-induced replication arrest in the xeroderma pigmentosum variant leads to DNA double-strand breaks, gamma-H2AX formation, and Mre11 relocalization
    • Limoli CL, Giedzinski E, Bonner WM & Cleaver JE (2002) UV-induced replication arrest in the xeroderma pigmentosum variant leads to DNA double-strand breaks, gamma-H2AX formation, and Mre11 relocalization. Proc Natl Acad Sci USA, 99(1): 233-238.
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.1 , pp. 233-238
    • Limoli, C.L.1    Giedzinski, E.2    Bonner, W.M.3    Cleaver, J.E.4
  • 258
    • 13644265943 scopus 로고    scopus 로고
    • The detection of gene mutation in transgenic mice (Big Blue®) following administration of a known mutagen 7,12-dimethylbenz[a]anthracene - (DMBA)
    • Lonardo EC, Perdue PA & Freeman JJ (1996) The detection of gene mutation in transgenic mice (Big Blue®) following administration of a known mutagen 7,12-dimethylbenz[a]anthracene - (DMBA). Abstr Annu Meet Environ Mutagen Soc, 1996: 42.
    • (1996) Abstr Annu Meet Environ Mutagen Soc , vol.1996 , pp. 42
    • Lonardo, E.C.1    Perdue, P.A.2    Freeman, J.J.3
  • 259
    • 0025866024 scopus 로고
    • An experimental approach to identifying the genotoxic risk from cooked meat mutagens
    • Loprieno N, Boncristiani G & Loprieno G (1991) An experimental approach to identifying the genotoxic risk from cooked meat mutagens. Food Chem Toxicol, 29(6): 377-386.
    • (1991) Food Chem Toxicol , vol.29 , Issue.6 , pp. 377-386
    • Loprieno, N.1    Boncristiani, G.2    Loprieno, G.3
  • 260
    • 0025648878 scopus 로고
    • Chromosome aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro. V: Results with 46 chemicals
    • Loveday KS, Anderson BE, Resnick MA & Zeiger E (1990) Chromosome aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro. V: Results with 46 chemicals. Environ Mol Mutagen, 16: 272-303.
    • (1990) Environ Mol Mutagen , vol.16 , pp. 272-303
    • Loveday, K.S.1    Anderson, B.E.2    Resnick, M.A.3    Zeiger, E.4
  • 261
    • 0031785632 scopus 로고    scopus 로고
    • Genetic analysis of PHIP intestinal mutations in Muta™Mouse
    • Lynch AM, Gooderham NJ, Davies DS & Boobis AR (1998) Genetic analysis of PHIP intestinal mutations in Muta™Mouse. Mutagenesis, 13(6): 601-605.
    • (1998) Mutagenesis , vol.13 , Issue.6 , pp. 601-605
    • Lynch, A.M.1    Gooderham, N.J.2    Davies, D.S.3    Boobis, A.R.4
  • 262
    • 0017882980 scopus 로고
    • Mutagenicity studies with praziquantel, a new anthelmintic drug, in mammalian systems
    • Machemer L & Lorke D (1978) Mutagenicity studies with praziquantel, a new anthelmintic drug, in mammalian systems. Arch Toxicol, 39: 187-197.
    • (1978) Arch Toxicol , vol.39 , pp. 187-197
    • Machemer, L.1    Lorke, D.2
  • 263
    • 33847161170 scopus 로고    scopus 로고
    • MAK (1976) β-Propiolacton. In: Gesundheitsschädliche Arbeitsstoffe: Toxikologisch-arbeitsmedizinische Begründung von MAK-Werten. 9. Deutsche Forschungsgemeinschaft (DFG). Weinheim, Wiley-VCH, pp 1-8.
    • MAK (1976) β-Propiolacton. In: Gesundheitsschädliche Arbeitsstoffe: Toxikologisch-arbeitsmedizinische Begründung von MAK-Werten. Vol. 9. Deutsche Forschungsgemeinschaft (DFG). Weinheim, Wiley-VCH, pp 1-8.
  • 264
    • 33847133866 scopus 로고    scopus 로고
    • MAK (1991) N-Nitrosamines. In: Occupational toxicants - critical data evaluation for MAK values and classification of carcinogens. 1. Deutsche Forschungsgemeinschaft (DFG). Weinheim, Wiley-VCH, pp 261-289.
    • MAK (1991) N-Nitrosamines. In: Occupational toxicants - critical data evaluation for MAK values and classification of carcinogens. Vol. 1. Deutsche Forschungsgemeinschaft (DFG). Weinheim, Wiley-VCH, pp 261-289.
  • 265
    • 33847123982 scopus 로고    scopus 로고
    • MAK (1994) Toluene-2,4-diamine. In: Occupational toxicants - critical data evaluation for MAK values and classification of carcinogens. 6. Deutsche Forschungsgemeinschaft (DFG). Weinheim, Wiley-VCH, pp 339-352.
    • MAK (1994) Toluene-2,4-diamine. In: Occupational toxicants - critical data evaluation for MAK values and classification of carcinogens. Vol. 6. Deutsche Forschungsgemeinschaft (DFG). Weinheim, Wiley-VCH, pp 339-352.
  • 266
    • 33847106386 scopus 로고    scopus 로고
    • MAK (1998) Trichloroethylene. In: Occupational toxicants - critical data evaluation for MAK values and classification of carcinogens. 10. Deutsche Forschungsgemeinschaft (DFG). Weinheim, Wiley-VCH, pp 221-236.
    • MAK (1998) Trichloroethylene. In: Occupational toxicants - critical data evaluation for MAK values and classification of carcinogens. Vol. 10. Deutsche Forschungsgemeinschaft (DFG). Weinheim, Wiley-VCH, pp 221-236.
  • 267
    • 33847163163 scopus 로고    scopus 로고
    • MAK (2000) Chloroform. In: Occupational toxicants - critical data evaluation for MAK values and classification of carcinogens. 14. Deutsche Forschungsgemeinschaft (DFG). Weinheim, Wiley-VCH, pp 19-58.
    • MAK (2000) Chloroform. In: Occupational toxicants - critical data evaluation for MAK values and classification of carcinogens. Vol. 14. Deutsche Forschungsgemeinschaft (DFG). Weinheim, Wiley-VCH, pp 19-58.
  • 268
    • 33847165704 scopus 로고    scopus 로고
    • MAK (2002a) Di(2-ethylhexyl)phthalat (DEHP). In: Gesundheitsschä dliche Arbeitsstoffe: Toxikologisch-arbeitsmedizinische Begründung von MAK-Werten. 4. Deutsche Forschungsgemeinschaft (DFG). Weinheim, Wiley-VCH, pp 1-81.
    • MAK (2002a) Di(2-ethylhexyl)phthalat (DEHP). In: Gesundheitsschä dliche Arbeitsstoffe: Toxikologisch-arbeitsmedizinische Begründung von MAK-Werten. Vol. 4. Deutsche Forschungsgemeinschaft (DFG). Weinheim, Wiley-VCH, pp 1-81.
  • 269
    • 33847104156 scopus 로고    scopus 로고
    • MAK (2002b) Carbon tetrachloride. In: Occupational toxicants - critical data evaluation for MAK values and classification of carcinogens. 18. Deutsche Forschungsgemeinschaft (DFG). Weinheim, Wiley-VCH, pp 82-106.
    • MAK (2002b) Carbon tetrachloride. In: Occupational toxicants - critical data evaluation for MAK values and classification of carcinogens. Vol. 18. Deutsche Forschungsgemeinschaft (DFG). Weinheim, Wiley-VCH, pp 82-106.
  • 270
    • 0034938274 scopus 로고    scopus 로고
    • Direct separation of in vivo and in vitro am3 revertants in transgenic mice carrying the ΦX174 am3, cs70 vector
    • Malling HV & Delongchamp RR (2001) Direct separation of in vivo and in vitro am3 revertants in transgenic mice carrying the ΦX174 am3, cs70 vector. Environ Mol Mutagen, 37: 345-355.
    • (2001) Environ Mol Mutagen , vol.37 , pp. 345-355
    • Malling, H.V.1    Delongchamp, R.R.2
  • 271
    • 0346728790 scopus 로고    scopus 로고
    • Three origins of ΦX174 am3 revertants in transgenic cell culture
    • Malling HV, Delongchamp RR & Valentine CR (2003) Three origins of ΦX174 am3 revertants in transgenic cell culture. Environ Mol Mutagen, 42: 258-273.
    • (2003) Environ Mol Mutagen , vol.42 , pp. 258-273
    • Malling, H.V.1    Delongchamp, R.R.2    Valentine, C.R.3
  • 272
    • 0032486138 scopus 로고    scopus 로고
    • Comparison of in vivo mutagenesis in the endogenous Hprt gene and the lacI transgene of Big Blue® rats treated with 7,12- dimethylbenz[a]anthracene
    • Manjanatha MG, Shelton SD, Aidoo A, Lyn-Cook LE & Casciano DA (1998) Comparison of in vivo mutagenesis in the endogenous Hprt gene and the lacI transgene of Big Blue® rats treated with 7,12- dimethylbenz[a]anthracene. Mutat Res, 401: 165-178.
    • (1998) Mutat Res , vol.401 , pp. 165-178
    • Manjanatha, M.G.1    Shelton, S.D.2    Aidoo, A.3    Lyn-Cook, L.E.4    Casciano, D.A.5
  • 273
    • 0033984184 scopus 로고    scopus 로고
    • DNA adduct formation and molecular analysis of in vivo lacI mutations in the mammary tissue of Big Blue® rats treated with 7,12-dimethylbenz[a]anthracene
    • Manjanatha MG, Shelton SD, Culp SJ, Blankenship LR & Casciano DA (2000) DNA adduct formation and molecular analysis of in vivo lacI mutations in the mammary tissue of Big Blue® rats treated with 7,12-dimethylbenz[a]anthracene. Carcinogenesis, 21(2): 265-273.
    • (2000) Carcinogenesis , vol.21 , Issue.2 , pp. 265-273
    • Manjanatha, M.G.1    Shelton, S.D.2    Culp, S.J.3    Blankenship, L.R.4    Casciano, D.A.5
  • 274
    • 0035805259 scopus 로고    scopus 로고
    • Genome sequencing. Celera assembles mouse genome; public labs plan new strategy
    • Marshall E (2001) Genome sequencing. Celera assembles mouse genome; public labs plan new strategy. Science, 292: 822-823.
    • (2001) Science , vol.292 , pp. 822-823
    • Marshall, E.1
  • 277
    • 0033737292 scopus 로고    scopus 로고
    • Characterization of mutations induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b)]pyridine in the colon of gpt delta transgenic mouse: Novel G:C deletions beside runs of identical bases
    • Masumura K, Matsui K, Yamada M, Horiguchi M, Ishida K, Watanabe M, Wakabayashi K & Nohmi T (2000) Characterization of mutations induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b)]pyridine in the colon of gpt delta transgenic mouse: novel G:C deletions beside runs of identical bases. Carcinogenesis, 21(11): 2049-2056.
    • (2000) Carcinogenesis , vol.21 , Issue.11 , pp. 2049-2056
    • Masumura, K.1    Matsui, K.2    Yamada, M.3    Horiguchi, M.4    Ishida, K.5    Watanabe, M.6    Wakabayashi, K.7    Nohmi, T.8
  • 278
    • 0036391767 scopus 로고    scopus 로고
    • Heavy-ion-induced mutations in the gpt delta transgenic mouse: Comparison of mutation spectra induced by heavy-ion, X-ray, and γ-ray radiation
    • Masumura K, Kuniya K, Kurobe T, Fukuoka M, Yatagai F & Nohmi T (2002) Heavy-ion-induced mutations in the gpt delta transgenic mouse: Comparison of mutation spectra induced by heavy-ion, X-ray, and γ-ray radiation. Environ Mol Mutagen, 40(3): 207-215.
    • (2002) Environ Mol Mutagen , vol.40 , Issue.3 , pp. 207-215
    • Masumura, K.1    Kuniya, K.2    Kurobe, T.3    Fukuoka, M.4    Yatagai, F.5    Nohmi, T.6
  • 279
    • 0018412086 scopus 로고
    • Chromosomal aberration tests on 29 chemicals combined with S9 mix in vitro
    • Matsuoka A, Hayashi M & Ishidate M (1979) Chromosomal aberration tests on 29 chemicals combined with S9 mix in vitro. Mutat Res, 66(3): 277-290.
    • (1979) Mutat Res , vol.66 , Issue.3 , pp. 277-290
    • Matsuoka, A.1    Hayashi, M.2    Ishidate, M.3
  • 281
    • 0025352906 scopus 로고
    • The in vivo micronucleus assay in mammalian bone marrow and peripheral blood. A report of the U.S. Environmental Protection Agency GENE-TOX Program
    • Mavoumin KH, Blakey DH, Cimino MC, Salamone MF & Heddle JA (1990) The in vivo micronucleus assay in mammalian bone marrow and peripheral blood. A report of the U.S. Environmental Protection Agency GENE-TOX Program. Mutat Res, 239: 29-80.
    • (1990) Mutat Res , vol.239 , pp. 29-80
    • Mavoumin, K.H.1    Blakey, D.H.2    Cimino, M.C.3    Salamone, M.F.4    Heddle, J.A.5
  • 282
    • 3042768117 scopus 로고    scopus 로고
    • Mutations induced by the carcinogenic pyrrolizidine alkaloid riddelline in the liver cII gene of transgenic Big Blue® rats
    • Mei N, Heflich RH, Chou MW & Chen T (2004) Mutations induced by the carcinogenic pyrrolizidine alkaloid riddelline in the liver cII gene of transgenic Big Blue® rats. Chem Res Toxicol, 17(6): 814-818.
    • (2004) Chem Res Toxicol , vol.17 , Issue.6 , pp. 814-818
    • Mei, N.1    Heflich, R.H.2    Chou, M.W.3    Chen, T.4
  • 283
  • 285
    • 0030014562 scopus 로고    scopus 로고
    • Comparison of the X-gal- and P-gal-based systems for screening of mutant λ/lacZ phages originating from the transgenic mouse strain 40.6
    • Mientjes EJ, Steenwinkel MJST, van Delft JHM, Lohman PHM & Baan RA (1996) Comparison of the X-gal- and P-gal-based systems for screening of mutant λ/lacZ phages originating from the transgenic mouse strain 40.6. Mutat Res, 360: 101-106.
    • (1996) Mutat Res , vol.360 , pp. 101-106
    • Mientjes, E.J.1    Steenwinkel, M.J.S.T.2    van Delft, J.H.M.3    Lohman, P.H.M.4    Baan, R.A.5
  • 289
    • 0028987864 scopus 로고
    • Transgenic animal models for detection of in vivo mutations
    • Mirsalis J, Monforte J & Winegar R (1995) Transgenic animal models for detection of in vivo mutations. Annu Rev Pharm Toxicol, 35: 145-164.
    • (1995) Annu Rev Pharm Toxicol , vol.35 , pp. 145-164
    • Mirsalis, J.1    Monforte, J.2    Winegar, R.3
  • 293
    • 18144442577 scopus 로고    scopus 로고
    • Mutagenicity of 2-amino-3-methylimidazol[4,5-f]quinolme in colon and liver of Big Blue® rats: Role of DNA adducts, strand breaks, DNA repair and oxidative stress
    • Møller P, Wallin H, Vogel U, Autrup H, Risom L, Hald MT, Daneshvar B, Dragsted LO, Poulsen HE & Loft S (2002) Mutagenicity of 2-amino-3-methylimidazol[4,5-f]quinolme in colon and liver of Big Blue® rats: role of DNA adducts, strand breaks, DNA repair and oxidative stress. Carcinogenesis, 23(8): 1379-1385.
    • (2002) Carcinogenesis , vol.23 , Issue.8 , pp. 1379-1385
    • Møller, P.1    Wallin, H.2    Vogel, U.3    Autrup, H.4    Risom, L.5    Hald, M.T.6    Daneshvar, B.7    Dragsted, L.O.8    Poulsen, H.E.9    Loft, S.10
  • 294
    • 0032511836 scopus 로고    scopus 로고
    • A comparative study of in vivo mutation assays: Analysis of Hprt, lacI, cII/cI as mutational targets for N-nitroso-N-methylurea and benzo[a]pyrene in Big Blue® mice
    • Monroe JJ, Kort KL, Miller JE, Marino DR & Skopek TR (1998) A comparative study of in vivo mutation assays: analysis of Hprt, lacI, cII/cI as mutational targets for N-nitroso-N-methylurea and benzo[a]pyrene in Big Blue® mice. Mutat Res, 421: 121-136.
    • (1998) Mutat Res , vol.421 , pp. 121-136
    • Monroe, J.J.1    Kort, K.L.2    Miller, J.E.3    Marino, D.R.4    Skopek, T.R.5
  • 295
    • 0030871409 scopus 로고    scopus 로고
    • Evaluation of the rodent micronucleus assay in the screening of IARC carcinogens (groups 1, 2A and 2B): The summary report of the 6th collaborative study by CSGMT/JEMS MMS. Collaborative Study of the Micronucleus Group Test. Mammalian Mutagenicity Study Group
    • Morita T, Asano N, Awogi T, Sasaki Y, Sato S, Shimada H, Sutou S, Suzuki T, Wakata A, Sofuni T & Hayashi M (1997a) Evaluation of the rodent micronucleus assay in the screening of IARC carcinogens (groups 1, 2A and 2B): The summary report of the 6th collaborative study by CSGMT/JEMS MMS. Collaborative Study of the Micronucleus Group Test. Mammalian Mutagenicity Study Group. Mutat Res, 389(1): 3-122.
    • (1997) Mutat Res , vol.389 , Issue.1 , pp. 3-122
    • Morita, T.1    Asano, N.2    Awogi, T.3    Sasaki, Y.4    Sato, S.5    Shimada, H.6    Sutou, S.7    Suzuki, T.8    Wakata, A.9    Sofuni, T.10    Hayashi, M.11
  • 296
    • 0030742385 scopus 로고    scopus 로고
    • Morita T, Asano N, Awogi T, Sasaki Y, Sato S, Shimada H, Sutou S, Suzuki T, Wakata A, Sofuni T & Hayashi M (1997b) Erratum to Evaluation of the rodent micronucleus assay in the screening of IARC carcinogens (groups 1, 2A and 2B): The summary report of the 6th collaborative study by CSGMT/JEMS MMS. Mutat Res, 391: 259-267.
    • Morita T, Asano N, Awogi T, Sasaki Y, Sato S, Shimada H, Sutou S, Suzuki T, Wakata A, Sofuni T & Hayashi M (1997b) Erratum to "Evaluation of the rodent micronucleus assay in the screening of IARC carcinogens (groups 1, 2A and 2B): The summary report of the 6th collaborative study by CSGMT/JEMS MMS." Mutat Res, 391: 259-267.
  • 297
    • 12644313085 scopus 로고
    • Studies of carcinogenicity in the rate of derivates of aromatic amines related to N-2-ftuorenylacetamtde
    • Morris HP, Velat CA, Wagner BP, Dahlgard M & Ray FE (1960) Studies of carcinogenicity in the rate of derivates of aromatic amines related to N-2-ftuorenylacetamtde. J Natl Cancer Inst, 24: 149-180.
    • (1960) J Natl Cancer Inst , vol.24 , pp. 149-180
    • Morris, H.P.1    Velat, C.A.2    Wagner, B.P.3    Dahlgard, M.4    Ray, F.E.5
  • 299
    • 0028922843 scopus 로고
    • Inhalation of benzene leads to an increase in the mutant frequencies of a lacI transgene in lung and spleen tissues of mice
    • Mullin AH, Rando R, Esmundo F & Mullin DA (1995) Inhalation of benzene leads to an increase in the mutant frequencies of a lacI transgene in lung and spleen tissues of mice. Mutat Res, 327: 121-129.
    • (1995) Mutat Res , vol.327 , pp. 121-129
    • Mullin, A.H.1    Rando, R.2    Esmundo, F.3    Mullin, D.A.4
  • 300
    • 0031684217 scopus 로고    scopus 로고
    • Inhaled benzene increases the frequency and length of lacI deletion mutations in lung tissues of mice
    • Mullin AH, Nataraj D, Ren J-J & Mullin DA (1998) Inhaled benzene increases the frequency and length of lacI deletion mutations in lung tissues of mice. Carcinogenesis, 19(10): 1723-1733.
    • (1998) Carcinogenesis , vol.19 , Issue.10 , pp. 1723-1733
    • Mullin, A.H.1    Nataraj, D.2    Ren, J.-J.3    Mullin, D.A.4
  • 301
    • 0025748131 scopus 로고
    • Validation studies with Muta Mouse: A transgenic mouse model for detecting mutations in vivo
    • Myhr B (1991) Validation studies with Muta Mouse: a transgenic mouse model for detecting mutations in vivo. Environ Mol Mutagen, 18(4): 308-315.
    • (1991) Environ Mol Mutagen , vol.18 , Issue.4 , pp. 308-315
    • Myhr, B.1
  • 302
    • 0033393815 scopus 로고    scopus 로고
    • A new approach to risk estimation of food-borne carcinogens heterocyclic amines - based on molecular information
    • Nagao M (1999) A new approach to risk estimation of food-borne carcinogens heterocyclic amines - based on molecular information. Mutat Res, 431(1): 3-12.
    • (1999) Mutat Res , vol.431 , Issue.1 , pp. 3-12
    • Nagao, M.1
  • 303
    • 0343031051 scopus 로고    scopus 로고
    • No direct correlation between mutant frequencies and cancer incidence induced by MeIQ in various organs of Big Blue® mice
    • Nagao M, Fujita H, Ochiai M, Wakabayashi K, Sofuni T, Matsushima T, Sugimura T & Ushijima T (1998) No direct correlation between mutant frequencies and cancer incidence induced by MeIQ in various organs of Big Blue® mice. Mutat Res, 400: 251-257.
    • (1998) Mutat Res , vol.400 , pp. 251-257
    • Nagao, M.1    Fujita, H.2    Ochiai, M.3    Wakabayashi, K.4    Sofuni, T.5    Matsushima, T.6    Sugimura, T.7    Ushijima, T.8
  • 304
    • 0035796054 scopus 로고    scopus 로고
    • LacI transgenic animal study: Relationships among DNA-adduct levels, mutant frequencies and cancer incidences
    • Nagao M, Ochiai M, Okochi E, Ushijima T & Sugimura T (2001) LacI transgenic animal study: relationships among DNA-adduct levels, mutant frequencies and cancer incidences. Mutat Res, 477: 119-124.
    • (2001) Mutat Res , vol.477 , pp. 119-124
    • Nagao, M.1    Ochiai, M.2    Okochi, E.3    Ushijima, T.4    Sugimura, T.5
  • 306
    • 13644269944 scopus 로고
    • Die Wirksamkeit von Natulan im Fellflecken-Test mit der Maus
    • Neuhäuser A (1977) Die Wirksamkeit von Natulan im Fellflecken-Test mit der Maus. GSF-Ber B, 798: 42-44.
    • (1977) GSF-Ber B , vol.798 , pp. 42-44
    • Neuhäuser, A.1
  • 307
    • 0023268633 scopus 로고
    • Studies on somatic mutation induction in the mouse with isoniazid and hydrazine
    • Neuhäuser-Klaus A & Chauhan P (1987) Studies on somatic mutation induction in the mouse with isoniazid and hydrazine. Mutat Res, 191: 111-116.
    • (1987) Mutat Res , vol.191 , pp. 111-116
    • Neuhäuser-Klaus, A.1    Chauhan, P.2
  • 308
    • 0024369555 scopus 로고
    • Mutagenic and teratogenic effects of acrylamide in the mammalian spot test
    • Neuhäuser-Klaus A & Schmahl W (1989) Mutagenic and teratogenic effects of acrylamide in the mammalian spot test. Mutat Res, 226(3): 157-162.
    • (1989) Mutat Res , vol.226 , Issue.3 , pp. 157-162
    • Neuhäuser-Klaus, A.1    Schmahl, W.2
  • 309
    • 0030331124 scopus 로고    scopus 로고
    • Spontaneous mutation in Big Blue® transgenic mice: Analysis of age, gender and tissue type
    • Nishino H, Buettner VL, Haavik J, Schaid DJ & Sommer SS (1996) Spontaneous mutation in Big Blue® transgenic mice: analysis of age, gender and tissue type. Environ Mol Mutagen, 28(4): 299-312.
    • (1996) Environ Mol Mutagen , vol.28 , Issue.4 , pp. 299-312
    • Nishino, H.1    Buettner, V.L.2    Haavik, J.3    Schaid, D.J.4    Sommer, S.S.5
  • 310
    • 2442586033 scopus 로고    scopus 로고
    • gpt delta transgenic mouse: A novel approach for molecular dissection of deletion mutations in vivo
    • Nohmi T & Masumura K (2004) gpt delta transgenic mouse: a novel approach for molecular dissection of deletion mutations in vivo. Adv Biophys, 38: 97-121.
    • (2004) Adv Biophys , vol.38 , pp. 97-121
    • Nohmi, T.1    Masumura, K.2
  • 311
    • 17044409204 scopus 로고    scopus 로고
    • Molecular nature of intrachromosomal deletions and base substitutions induced by environmental mutagens
    • Nohmi T & Masumura K (2005) Molecular nature of intrachromosomal deletions and base substitutions induced by environmental mutagens. Environ Mol Mutagen, 45: 150-161.
    • (2005) Environ Mol Mutagen , vol.45 , pp. 150-161
    • Nohmi, T.1    Masumura, K.2
  • 314
    • 0034693862 scopus 로고    scopus 로고
    • Recent advances in the protocols of transgenic mouse mutation assays
    • Nohmi T, Suzuki T & Masumura K (2000) Recent advances in the protocols of transgenic mouse mutation assays. Mutat Res, 455(1-2): 191-215.
    • (2000) Mutat Res , vol.455 , Issue.1-2 , pp. 191-215
    • Nohmi, T.1    Suzuki, T.2    Masumura, K.3
  • 315
    • 33847114783 scopus 로고    scopus 로고
    • NTP (2003a) 2-Acetylaminofluorene. CAS: 53-96-3. Research Triangle Park, North Carolina, United States Department of Health and Human Services, National Toxicology Program (Factsheet; http://ntp-server.niehs.nih.gov/index.cfm? objectid=6DDF4AD9-F1F6-975E-7A0747B910250667; last updated 4 September 2003; accessed 11 November 2004).
    • NTP (2003a) 2-Acetylaminofluorene. CAS: 53-96-3. Research Triangle Park, North Carolina, United States Department of Health and Human Services, National Toxicology Program (Factsheet; http://ntp-server.niehs.nih.gov/index.cfm? objectid=6DDF4AD9-F1F6-975E-7A0747B910250667; last updated 4 September 2003; accessed 11 November 2004).
  • 316
    • 33847171853 scopus 로고    scopus 로고
    • NTP (2003b) 2,6-Toluenediamine dihydrochloride (2,6-diaminotoluene dihydrochloride). CAS 15481-70-6. Research Triangle Park, North Carolina, United States Department of Health and Human Services, National Toxicology Program (Factsheet: http://ntp.niehs.nih.gov/index.cfm?objectid=0718C4BA-E9A2-42AB- A9634AF5BFA7D317; last updated 4 September 2003; accessed 11 November 2004).
    • NTP (2003b) 2,6-Toluenediamine dihydrochloride (2,6-diaminotoluene dihydrochloride). CAS 15481-70-6. Research Triangle Park, North Carolina, United States Department of Health and Human Services, National Toxicology Program (Factsheet: http://ntp.niehs.nih.gov/index.cfm?objectid=0718C4BA-E9A2-42AB- A9634AF5BFA7D317; last updated 4 September 2003; accessed 11 November 2004).
  • 317
    • 0031822922 scopus 로고    scopus 로고
    • DNA adduct level induced by 2-amino-3,4-dimethylimidazo[4,5- f]-quinoline in Big Blue® mice does not correlate with mutagenicity
    • Ochiai M, Ishida K, Ushijima T, Suzuki T, Sofuni T, Sugimura T & Nagao M (1998) DNA adduct level induced by 2-amino-3,4-dimethylimidazo[4,5- f]-quinoline in Big Blue® mice does not correlate with mutagenicity. Mutagenesis, 13(4): 381-384.
    • (1998) Mutagenesis , vol.13 , Issue.4 , pp. 381-384
    • Ochiai, M.1    Ishida, K.2    Ushijima, T.3    Suzuki, T.4    Sofuni, T.5    Sugimura, T.6    Nagao, M.7
  • 318
    • 33847097829 scopus 로고
    • OECD guideline for the testing of chemicals. OECD 486: Unscheduled DNA synthesis (UDS) test with mammalian liver cells in vivo. Paris
    • OECD
    • OECD (1971) OECD guideline for the testing of chemicals. OECD 486: Unscheduled DNA synthesis (UDS) test with mammalian liver cells in vivo. Paris, Organisation for Economic Co-operation and Development, pp 1-8.
    • (1971) Organisation for Economic Co-operation and Development , pp. 1-8
  • 319
    • 79953666146 scopus 로고
    • OECD guideline for the testing of chemicals. OECD 451: Carcinogenicity studies. Paris
    • OECD
    • OECD (1981) OECD guideline for the testing of chemicals. OECD 451: Carcinogenicity studies. Paris, Organisation for Economic Co-operation and Development, pp 1-17.
    • (1981) Organisation for Economic Co-operation and Development , pp. 1-17
  • 320
    • 33847161169 scopus 로고
    • OECD guideline for the testing of chemicals. OECD 477: Genetic toxicology: Sex-linked recessive lethal test in Drosophila melanogaster. Paris
    • OECD
    • OECD (1984a) OECD guideline for the testing of chemicals. OECD 477: Genetic toxicology: Sex-linked recessive lethal test in Drosophila melanogaster. Paris, Organisation for Economic Co-operation and Development, pp 1-6.
    • (1984) Organisation for Economic Co-operation and Development , pp. 1-6
  • 321
    • 33847093781 scopus 로고
    • OECD guideline for the testing of chemicals. OECD 478: Genetic toxicology: Rodent dominant lethal test. Paris
    • OECD
    • OECD (1984b) OECD guideline for the testing of chemicals. OECD 478: Genetic toxicology: Rodent dominant lethal test. Paris, Organisation for Economic Co-operation and Development, pp 1-6.
    • (1984) Organisation for Economic Co-operation and Development , pp. 1-6
  • 322
    • 84886002703 scopus 로고
    • OECD guideline for the testing of chemicals. OECD 484: Genetic toxicology: mouse spot test. Paris
    • OECD
    • OECD (1986a) OECD guideline for the testing of chemicals. OECD 484: Genetic toxicology: mouse spot test. Paris, Organisation for Economic Co-operation and Development, pp 1-4.
    • (1986) Organisation for Economic Co-operation and Development , pp. 1-4
  • 323
    • 84886041799 scopus 로고
    • OECD guideline for the testing of chemicals. OECD 485: Genetic toxicology: Mouse heritable translocation assay. Paris
    • OECD
    • OECD (1986b) OECD guideline for the testing of chemicals. OECD 485: Genetic toxicology: Mouse heritable translocation assay. Paris, Organisation for Economic Co-operation and Development, pp 1-6.
    • (1986) Organisation for Economic Co-operation and Development , pp. 1-6
  • 324
    • 54049122062 scopus 로고    scopus 로고
    • OECD guideline for the testing of chemicals. OECD 474: Mammalian erythrocyte micronucleus test. Paris
    • OECD
    • OECD (1997a) OECD guideline for the testing of chemicals. OECD 474: Mammalian erythrocyte micronucleus test. Paris, Organisation for Economic Co-operation and Development, pp 1-10.
    • (1997) Organisation for Economic Co-operation and Development , pp. 1-10
  • 325
    • 54049122062 scopus 로고    scopus 로고
    • OECD guideline for the testing of chemicals. OECD 475: Mammalian bone marrow chromosome aberration test. Paris
    • OECD
    • OECD (1997b) OECD guideline for the testing of chemicals. OECD 475: Mammalian bone marrow chromosome aberration test. Paris, Organisation for Economic Co-operation and Development, pp 1-8.
    • (1997) Organisation for Economic Co-operation and Development , pp. 1-8
  • 326
    • 54049122062 scopus 로고    scopus 로고
    • OECD guideline for the testing of chemicals. OECD 483: Mammalian spermatogonial chromosome aberration test. Paris
    • OECD
    • OECD (1997c) OECD guideline for the testing of chemicals. OECD 483: Mammalian spermatogonial chromosome aberration test. Paris, Organisation for Economic Co-operation and Development, pp 1-8.
    • (1997) Organisation for Economic Co-operation and Development , pp. 1-8
  • 327
    • 0034694163 scopus 로고    scopus 로고
    • Genotoxicity of o-aminoazotoluene (AAT) determined by the Ames test, the in vitro chromosomal aberration test, and the transgenic mouse gene mutation assay
    • Ohsawa K, Hirano N, Sugiura M, Nakagawa S & Kimura M (2000) Genotoxicity of o-aminoazotoluene (AAT) determined by the Ames test, the in vitro chromosomal aberration test, and the transgenic mouse gene mutation assay. Mutat Res, 471: 113-126.
    • (2000) Mutat Res , vol.471 , pp. 113-126
    • Ohsawa, K.1    Hirano, N.2    Sugiura, M.3    Nakagawa, S.4    Kimura, M.5
  • 328
    • 0030946794 scopus 로고    scopus 로고
    • Sodium phenobarbital-enhanced mutation frequency in the liver DNA of lacZ transgenic mice treated with diethylnitrosamine
    • Okada N, Honda A, Kawabata M & Yajima N (1997) Sodium phenobarbital-enhanced mutation frequency in the liver DNA of lacZ transgenic mice treated with diethylnitrosamine. Mutagenesis, 12:179-184.
    • (1997) Mutagenesis , vol.12 , pp. 179-184
    • Okada, N.1    Honda, A.2    Kawabata, M.3    Yajima, N.4
  • 329
    • 0032877006 scopus 로고    scopus 로고
    • Preferential induction of guanine deletion at 5′-GGGA-3′ in rat mammary glands by 2-amino-1-methyl-6- phenylimidazo[4,5-b]pyridine
    • Okochi E, Watanabe N, Shimada Y, Takahashi S, Wakazono K, Shirai T, Sugimura T, Nagao M & Ushijima T (1999) Preferential induction of guanine deletion at 5′-GGGA-3′ in rat mammary glands by 2-amino-1-methyl-6- phenylimidazo[4,5-b]pyridine. Carcinogenesis, 20(10): 1933-1938.
    • (1999) Carcinogenesis , vol.20 , Issue.10 , pp. 1933-1938
    • Okochi, E.1    Watanabe, N.2    Shimada, Y.3    Takahashi, S.4    Wakazono, K.5    Shirai, T.6    Sugimura, T.7    Nagao, M.8    Ushijima, T.9
  • 330
    • 0031566023 scopus 로고    scopus 로고
    • Effects of gender and species on spectra of mutation induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in the lacI transgene
    • Okonogi H, Stuart GR, Okochi E, Ushijima T, Sugimura T, Glickman BW & Nagao M (1997) Effects of gender and species on spectra of mutation induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in the lacI transgene. Mutat Res, 395: 93-99.
    • (1997) Mutat Res , vol.395 , pp. 93-99
    • Okonogi, H.1    Stuart, G.R.2    Okochi, E.3    Ushijima, T.4    Sugimura, T.5    Glickman, B.W.6    Nagao, M.7
  • 331
    • 0031756760 scopus 로고    scopus 로고
    • Spontaneous mutation during fetal development and post-natal growth
    • Paashuis-Lew YR & Heddle JA (1998) Spontaneous mutation during fetal development and post-natal growth. Mutagenesis, 13(6): 613-617.
    • (1998) Mutagenesis , vol.13 , Issue.6 , pp. 613-617
    • Paashuis-Lew, Y.R.1    Heddle, J.A.2
  • 332
    • 0030721962 scopus 로고    scopus 로고
    • On the origin of spontaneous somatic mutations and sectored plaques detected in transgenic mice
    • Paashuis-Lew Y, Zhang XB & Heddle JA (1997) On the origin of spontaneous somatic mutations and sectored plaques detected in transgenic mice. Mutat Res, 373(2): 277-284.
    • (1997) Mutat Res , vol.373 , Issue.2 , pp. 277-284
    • Paashuis-Lew, Y.1    Zhang, X.B.2    Heddle, J.A.3
  • 335
    • 0032416598 scopus 로고    scopus 로고
    • Methyl bromide causes DNA methylation in rats and mice but fails to induce somatic mutations in lambda lacZ transgenic mice
    • Pletsa V, Steenwinkel MJ, van Delft JH, Baan RA & Kyrtopoulos SA (1999) Methyl bromide causes DNA methylation in rats and mice but fails to induce somatic mutations in lambda lacZ transgenic mice. Cancer Lett, 135(1): 21-27.
    • (1999) Cancer Lett , vol.135 , Issue.1 , pp. 21-27
    • Pletsa, V.1    Steenwinkel, M.J.2    van Delft, J.H.3    Baan, R.A.4    Kyrtopoulos, S.A.5
  • 336
    • 0028227149 scopus 로고
    • Characterization of mutations induced by ethylnitrosourea in seminiferous tubule germ cells of transgenic B6C3F1 mice
    • Provost GS & Short JM (1994) Characterization of mutations induced by ethylnitrosourea in seminiferous tubule germ cells of transgenic B6C3F1 mice. Proc Natl Acad Sci USA, 91: 6564-6568.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 6564-6568
    • Provost, G.S.1    Short, J.M.2
  • 338
    • 0030329356 scopus 로고    scopus 로고
    • Mutagenic response to benzene and tris(2,3-dibromopropyl)-phosphate in the lambda lacI transgenic mouse mutation assay: A standardized approach to in vivo mutation analysis
    • Provost GS, Mirsalis JC, Rogers BJ & Short JM (1996) Mutagenic response to benzene and tris(2,3-dibromopropyl)-phosphate in the lambda lacI transgenic mouse mutation assay: a standardized approach to in vivo mutation analysis. Environ Mol Mutagen, 28: 342-347.
    • (1996) Environ Mol Mutagen , vol.28 , pp. 342-347
    • Provost, G.S.1    Mirsalis, J.C.2    Rogers, B.J.3    Short, J.M.4
  • 339
    • 0342617768 scopus 로고    scopus 로고
    • Evaluation of spontaneous and chemical-induced lacI mutations in germ cells from λ/lacI transgenic mice
    • Putman DL, Penn Ritter A, Carr GJ & Young RR (1997) Evaluation of spontaneous and chemical-induced lacI mutations in germ cells from λ/lacI transgenic mice. Mutat Res, 388: 137-143.
    • (1997) Mutat Res , vol.388 , pp. 137-143
    • Putman, D.L.1    Penn Ritter, A.2    Carr, G.J.3    Young, R.R.4
  • 341
    • 0027793709 scopus 로고
    • Use of transgenic mice for assessing the mutagenicity of 1,3-butadiene in vivo
    • Sorsa M, Peltonen K, Vainio H & Hemminki K eds, Lyon, International Agency for Research on Cancer, pp, IARC Scientific Publications No. 127
    • Recio L, Bond JA, Pluta LJ & Sisk SC (1993) Use of transgenic mice for assessing the mutagenicity of 1,3-butadiene in vivo. In: Sorsa M, Peltonen K, Vainio H & Hemminki K eds. Butadiene and styrene: assessment of health hazards. Lyon, International Agency for Research on Cancer, pp 235-243 (IARC Scientific Publications No. 127).
    • (1993) Butadiene and styrene: Assessment of health hazards , pp. 235-243
    • Recio, L.1    Bond, J.A.2    Pluta, L.J.3    Sisk, S.C.4
  • 342
    • 0030331126 scopus 로고    scopus 로고
    • Assessment of 1,3-butadiene mutagenicity in the bone marrow of B6C3F1 lacI transgenic mice (Big Blue®): A review of mutational spectrum and lacI mutant frequency after a 5-day 625 ppm 1,3-butadiene exposure
    • Recio L, Meyer KG, Pluta LJ, Moss OR & Saranko CJ (1996) Assessment of 1,3-butadiene mutagenicity in the bone marrow of B6C3F1 lacI transgenic mice (Big Blue®): a review of mutational spectrum and lacI mutant frequency after a 5-day 625 ppm 1,3-butadiene exposure. Environ Mol Mutagen, 28: 424-429.
    • (1996) Environ Mol Mutagen , vol.28 , pp. 424-429
    • Recio, L.1    Meyer, K.G.2    Pluta, L.J.3    Moss, O.R.4    Saranko, C.J.5
  • 343
    • 2942583950 scopus 로고    scopus 로고
    • In vivo mutagenicity and mutation spectrum in the bone marrow and testes of B6C3F1 lacI transgenic mice following inhalation exposure to ethylene oxide
    • Recio L, Donner M, Abemethy D, Pluta L, Steen AM, Wong BA, James A & Preston RJ (2004) In vivo mutagenicity and mutation spectrum in the bone marrow and testes of B6C3F1 lacI transgenic mice following inhalation exposure to ethylene oxide. Mutagenesis, 19(3): 215-222.
    • (2004) Mutagenesis , vol.19 , Issue.3 , pp. 215-222
    • Recio, L.1    Donner, M.2    Abemethy, D.3    Pluta, L.4    Steen, A.M.5    Wong, B.A.6    James, A.7    Preston, R.J.8
  • 344
    • 0030981576 scopus 로고    scopus 로고
    • Effect of ethylnitrosourea and methyl methanesulfonate on mutation frequency in Muta™Mouse germ cells (seminiferous tubule cells and epididymis spermatozoa)
    • Renault D, Brault D & Thybaud V (1997) Effect of ethylnitrosourea and methyl methanesulfonate on mutation frequency in Muta™Mouse germ cells (seminiferous tubule cells and epididymis spermatozoa). Mutat Res, 388: 145-153.
    • (1997) Mutat Res , vol.388 , pp. 145-153
    • Renault, D.1    Brault, D.2    Thybaud, V.3
  • 346
    • 33847132716 scopus 로고    scopus 로고
    • Mutagenicity of chemicals in genetically modified animals. Bilthoven, National Institute of Public Health and the Environment (RIVM)
    • RIVM , No. 650210 002; TNO Report No. V99.1097
    • RIVM (2000) Mutagenicity of chemicals in genetically modified animals. Bilthoven, National Institute of Public Health and the Environment (RIVM), pp 1-47 (RIVM Report No. 650210 002; TNO Report No. V99.1097).
    • (2000) pp 1-47 (RIVM Report
  • 347
    • 0032559676 scopus 로고    scopus 로고
    • Increased frequency of micronucleated kidney cells in rats exposed to halogenated anaesthetics
    • Robbiano L, Mereto E, Morando AM, Pastore P & Brambilla G (1998) Increased frequency of micronucleated kidney cells in rats exposed to halogenated anaesthetics. Mutat Res, 413: 1-6.
    • (1998) Mutat Res , vol.413 , pp. 1-6
    • Robbiano, L.1    Mereto, E.2    Morando, A.M.3    Pastore, P.4    Brambilla, G.5
  • 348
    • 0028912913 scopus 로고
    • Intralaboratory optimization and standardization of mutant screening conditions used for a lambda/lacI transgenic mouse mutagenesis assay (I)
    • Rogers BJ, Provost GS, Young RR, Putman DL & Short JM (1995) Intralaboratory optimization and standardization of mutant screening conditions used for a lambda/lacI transgenic mouse mutagenesis assay (I). Mutat Res, 327: 57-66.
    • (1995) Mutat Res , vol.327 , pp. 57-66
    • Rogers, B.J.1    Provost, G.S.2    Young, R.R.3    Putman, D.L.4    Short, J.M.5
  • 349
    • 0031884838 scopus 로고    scopus 로고
    • Induction of mutations by 2-acetylaminofluorene in lacI transgenic B6C3F1 mouse liver
    • Ross JA & Leavitt SA (1998) Induction of mutations by 2-acetylaminofluorene in lacI transgenic B6C3F1 mouse liver. Mutagenesis, 13: 173-179.
    • (1998) Mutagenesis , vol.13 , pp. 173-179
    • Ross, J.A.1    Leavitt, S.A.2
  • 350
    • 0019518609 scopus 로고
    • Use of the mouse spot test in chemical mutagenesis: Interpretation of past data and recommendations for future work
    • Russell LB, Selby PB, von Halle E, Sheridan W & Valcovic L (1981) Use of the mouse spot test in chemical mutagenesis: interpretation of past data and recommendations for future work. Mutat Res, 86: 355-379.
    • (1981) Mutat Res , vol.86 , pp. 355-379
    • Russell, L.B.1    Selby, P.B.2    von Halle, E.3    Sheridan, W.4    Valcovic, L.5
  • 353
    • 0022446219 scopus 로고
    • Mechanisms of spontaneous mutagenesis: An analysis of the spectrum of spontaneous mutation in the Escherichia coli lacI gene
    • Schaaper RM, Danforth BN & Glickman BW (1986) Mechanisms of spontaneous mutagenesis: an analysis of the spectrum of spontaneous mutation in the Escherichia coli lacI gene. J Mol Biol, 189(2): 273-284.
    • (1986) J Mol Biol , vol.189 , Issue.2 , pp. 273-284
    • Schaaper, R.M.1    Danforth, B.N.2    Glickman, B.W.3
  • 354
    • 0025326603 scopus 로고
    • N-Acetoxy- N-acetyl-2-aminofluorene-induced mutagenesis in the lacI gene of Escherichia coli
    • Schaaper RM, Koffel-Schwartz N & Fuchs RP (1990) N-Acetoxy- N-acetyl-2-aminofluorene-induced mutagenesis in the lacI gene of Escherichia coli. Carcinogenesis, 11(7): 1087-1095.
    • (1990) Carcinogenesis , vol.11 , Issue.7 , pp. 1087-1095
    • Schaaper, R.M.1    Koffel-Schwartz, N.2    Fuchs, R.P.3
  • 356
    • 0032616056 scopus 로고    scopus 로고
    • Induction of mutations in transgenic animal models: Big Blue® and Muta™Mouse
    • McGregor DB, Rice JM & Venitt S eds, Lyon, International Agency for Research on Cancer, pp, IARC Scientific Publications No. 146
    • Schmezer P & Eckert C (1999) Induction of mutations in transgenic animal models: Big Blue® and Muta™Mouse. In: McGregor DB, Rice JM & Venitt S eds. The use of short-and medium-term tests for carcinogens and data on genetic effects in carcinogenic hazard evaluation. Lyon, International Agency for Research on Cancer, pp 367-394 (IARC Scientific Publications No. 146).
    • (1999) The use of short-and medium-term tests for carcinogens and data on genetic effects in carcinogenic hazard evaluation , pp. 367-394
    • Schmezer, P.1    Eckert, C.2
  • 357
    • 0032552574 scopus 로고    scopus 로고
    • Mutagenic activity of carcinogens detected in transgenic rodent mutagenicity assays at dose levels used in chronic rodent cancer bioassays
    • Schmezer P, Eckert C, Liegibel U, Zelezny O & Klein R (1998a) Mutagenic activity of carcinogens detected in transgenic rodent mutagenicity assays at dose levels used in chronic rodent cancer bioassays. Mutat Res, 405: 193-198.
    • (1998) Mutat Res , vol.405 , pp. 193-198
    • Schmezer, P.1    Eckert, C.2    Liegibel, U.3    Zelezny, O.4    Klein, R.5
  • 358
    • 0031609093 scopus 로고    scopus 로고
    • Use of transgenic mutational test systems in risk assessment of carcinogens
    • Schmezer P, Eckert C, Liegibel U, Klein R & Bartsch H (1998b) Use of transgenic mutational test systems in risk assessment of carcinogens. Arch Toxicol Suppl, 20: 321-330.
    • (1998) Arch Toxicol Suppl , vol.20 , pp. 321-330
    • Schmezer, P.1    Eckert, C.2    Liegibel, U.3    Klein, R.4    Bartsch, H.5
  • 359
    • 0030914357 scopus 로고    scopus 로고
    • Mutant frequency of lacI in transgenic mice following benzo[a]pyrene treatment and partial hepatectomy
    • Shane BS, Lockhart AM, Winston GW & Tindall KR (1997) Mutant frequency of lacI in transgenic mice following benzo[a]pyrene treatment and partial hepatectomy. Mutat Res, 377: 1-11.
    • (1997) Mutat Res , vol.377 , pp. 1-11
    • Shane, B.S.1    Lockhart, A.M.2    Winston, G.W.3    Tindall, K.R.4
  • 361
    • 0034683670 scopus 로고    scopus 로고
    • Mutant frequencies and mutation spectra of dimethylnitrosamine (DMN) at the lacI and cII loci in the livers of Big Blue® transgenic mice
    • Shane BS, Smith-Dunn DL, de Boer JG, Glickman BW & Cunningham ML (2000b) Mutant frequencies and mutation spectra of dimethylnitrosamine (DMN) at the lacI and cII loci in the livers of Big Blue® transgenic mice. Mutat Res, 452: 197-210.
    • (2000) Mutat Res , vol.452 , pp. 197-210
    • Shane, B.S.1    Smith-Dunn, D.L.2    de Boer, J.G.3    Glickman, B.W.4    Cunningham, M.L.5
  • 362
    • 0034646274 scopus 로고    scopus 로고
    • Subchronic administration of phenobarbital alters the mutation spectrum of lacI in the livers of Big Blue® transgenic mice
    • Shane BS, Smith-Dunn DL, deBoer JG, Glickman BW & Cunningham ML (2000c) Subchronic administration of phenobarbital alters the mutation spectrum of lacI in the livers of Big Blue® transgenic mice. Mutat Res, 448: 69-80.
    • (2000) Mutat Res , vol.448 , pp. 69-80
    • Shane, B.S.1    Smith-Dunn, D.L.2    deBoer, J.G.3    Glickman, B.W.4    Cunningham, M.L.5
  • 363
    • 0029612230 scopus 로고
    • Enhanced somatic mutation rates induced in stem cells of mice by low chronic exposure to ethylnitrosourea
    • Shaver-Walker PM, Urlando C, Tao KS, Zhang XB & Heddle JA (1995) Enhanced somatic mutation rates induced in stem cells of mice by low chronic exposure to ethylnitrosourea. Proc Natl Acad Sci USA, 92: 11470-11474.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 11470-11474
    • Shaver-Walker, P.M.1    Urlando, C.2    Tao, K.S.3    Zhang, X.B.4    Heddle, J.A.5
  • 364
    • 0029012454 scopus 로고
    • Comparison of results from mouse bone marrow chromosome aberration and micronucleus tests
    • Shelby MD & Wilt KL (1995) Comparison of results from mouse bone marrow chromosome aberration and micronucleus tests. Environ Mol Mutagen, 25: 302-313.
    • (1995) Environ Mol Mutagen , vol.25 , pp. 302-313
    • Shelby, M.D.1    Wilt, K.L.2
  • 365
    • 0027526525 scopus 로고
    • Evaluation of a three-exposure mouse bone marrow micronucleus protocol: Results with 49 chemicals
    • Shelby MD, Erexson GL, Hook GJ & Tice RR (1993) Evaluation of a three-exposure mouse bone marrow micronucleus protocol: results with 49 chemicals. Environ Mol Mutagen, 21: 160-179.
    • (1993) Environ Mol Mutagen , vol.21 , pp. 160-179
    • Shelby, M.D.1    Erexson, G.L.2    Hook, G.J.3    Tice, R.R.4
  • 366
    • 0033754118 scopus 로고    scopus 로고
    • Mutant frequency and molecular analysis of in vivo lacI mutations in the bone marrow of Big Blue® rats treated with 7,12-dimethylbenz[a]anthracene
    • Shelton SD, Cherry V & Manjanatha MG (2000) Mutant frequency and molecular analysis of in vivo lacI mutations in the bone marrow of Big Blue® rats treated with 7,12-dimethylbenz[a]anthracene. Environ Mol Mutagen, 36: 235-242.
    • (2000) Environ Mol Mutagen , vol.36 , pp. 235-242
    • Shelton, S.D.1    Cherry, V.2    Manjanatha, M.G.3
  • 367
    • 0027311053 scopus 로고
    • Mutations in liver DNA of lacI transgenic mice (Big Blue®) following subchronic exposure to 2-acetylaminofluorene
    • Shephard SE, Sengstag C, Lutz WK & Schlatter C (1993) Mutations in liver DNA of lacI transgenic mice (Big Blue®) following subchronic exposure to 2-acetylaminofluorene. Mutat Res, 302: 91-96.
    • (1993) Mutat Res , vol.302 , pp. 91-96
    • Shephard, S.E.1    Sengstag, C.2    Lutz, W.K.3    Schlatter, C.4
  • 368
    • 0028921230 scopus 로고
    • Genotoxicity of agaritine in the lacI transgenic mouse mutation assay: Evaluation of the health risk of mushroom consumption
    • Shephard SE, Gunz D & Schlatter C (1995) Genotoxicity of agaritine in the lacI transgenic mouse mutation assay: evaluation of the health risk of mushroom consumption. Food Chem Toxicol, 33: 257-264.
    • (1995) Food Chem Toxicol , vol.33 , pp. 257-264
    • Shephard, S.E.1    Gunz, D.2    Schlatter, C.3
  • 369
    • 20044369162 scopus 로고    scopus 로고
    • Parp-1 deficiency causes an increase of deletion mutations and insertions/ rearrangements in vivo after treatment with an alkylating agent
    • Shibata A, Kamada N, Masumura K, Nohmi T, Kobayashi S, Teraoka H, Nakagama H, Sugimura T, Suzuki H & Masutani M (2005) Parp-1 deficiency causes an increase of deletion mutations and insertions/ rearrangements in vivo after treatment with an alkylating agent. Oncogene, 24(8): 1328-1337.
    • (2005) Oncogene , vol.24 , Issue.8 , pp. 1328-1337
    • Shibata, A.1    Kamada, N.2    Masumura, K.3    Nohmi, T.4    Kobayashi, S.5    Teraoka, H.6    Nakagama, H.7    Sugimura, T.8    Suzuki, H.9    Masutani, M.10
  • 370
    • 0345625740 scopus 로고
    • A review of the genotoxicity of 1-ethyl-1-nitrosourea
    • Shibuya T & Morimoto K (1993) A review of the genotoxicity of 1-ethyl-1-nitrosourea. Mutat Res, 297(1): 3-38.
    • (1993) Mutat Res , vol.297 , Issue.1 , pp. 3-38
    • Shibuya, T.1    Morimoto, K.2
  • 371
    • 0026599056 scopus 로고
    • The micronucleus test of benzo[a]pyrene with mouse and rat peripheral blood reticulocytes
    • Shimada H, Suzuki H, Itoh S, Hattori C, Matsuura Y, Tada S & Watanabe C (1992) The micronucleus test of benzo[a]pyrene with mouse and rat peripheral blood reticulocytes. Mutat Res, 278: 165-168.
    • (1992) Mutat Res , vol.278 , pp. 165-168
    • Shimada, H.1    Suzuki, H.2    Itoh, S.3    Hattori, C.4    Matsuura, Y.5    Tada, S.6    Watanabe, C.7
  • 372
    • 0035885262 scopus 로고    scopus 로고
    • Comparison of the mutant frequencies and mutation spectra of three non-genotoxic carcinogens, oxazepam, phenobarbital, and Weyth 14,643, at the lambdacII locus in Big Blue® transgenic mice
    • Singh VK, Ganesh L, Cunningham ML & Shane BS (2001) Comparison of the mutant frequencies and mutation spectra of three non-genotoxic carcinogens, oxazepam, phenobarbital, and Weyth 14,643, at the lambdacII locus in Big Blue® transgenic mice. Biochem Pharmacol, 62(6): 685-692.
    • (2001) Biochem Pharmacol , vol.62 , Issue.6 , pp. 685-692
    • Singh, V.K.1    Ganesh, L.2    Cunningham, M.L.3    Shane, B.S.4
  • 373
    • 0028181694 scopus 로고
    • Molecular analysis of lacI mutants from bone marrow of B6C3F1 transgenic mice following inhalation exposure to 1,3-butadiene
    • Sisk SC, Pluta L, Bond JA & Recio L (1994) Molecular analysis of lacI mutants from bone marrow of B6C3F1 transgenic mice following inhalation exposure to 1,3-butadiene. Carcinogenesis, 15(3): 471-477.
    • (1994) Carcinogenesis , vol.15 , Issue.3 , pp. 471-477
    • Sisk, S.C.1    Pluta, L.2    Bond, J.A.3    Recio, L.4
  • 374
    • 0030807682 scopus 로고    scopus 로고
    • Assessment of the in vivo mutagenicity of ethylene oxide in the tissues of B6C3F1 lacI transgenic mice following inhalation exposure
    • Sisk SC, Pluta LJ, Meyer KG, Wong BC & Recio L (1997) Assessment of the in vivo mutagenicity of ethylene oxide in the tissues of B6C3F1 lacI transgenic mice following inhalation exposure. Mutat Res, 391: 153-164.
    • (1997) Mutat Res , vol.391 , pp. 153-164
    • Sisk, S.C.1    Pluta, L.J.2    Meyer, K.G.3    Wong, B.C.4    Recio, L.5
  • 375
    • 0028991066 scopus 로고
    • Relative sensitivity of the endogenous Hprt gene and lacI transgene in ENU-treated Big Blue® B6C3F1 mice
    • Skopek TR, Kort KL & Marino DR (1995) Relative sensitivity of the endogenous Hprt gene and lacI transgene in ENU-treated Big Blue® B6C3F1 mice. Environ Mol Mutagen, 26: 9-15.
    • (1995) Environ Mol Mutagen , vol.26 , pp. 9-15
    • Skopek, T.R.1    Kort, K.L.2    Marino, D.R.3
  • 377
    • 0037229327 scopus 로고    scopus 로고
    • Development of a microplate assay for the detection of single plaque-forming units of bacteriophage ΦX174 in crude lysates
    • Slattery SD & Valentine CR (2003) Development of a microplate assay for the detection of single plaque-forming units of bacteriophage ΦX174 in crude lysates. Environ Mol Mutagen, 41: 121-125.
    • (2003) Environ Mol Mutagen , vol.41 , pp. 121-125
    • Slattery, S.D.1    Valentine, C.R.2
  • 378
    • 4444280106 scopus 로고    scopus 로고
    • N-Ethyl-N-nitrosourea (ENU) increased brain mutations in prenatal and neonatal mice but not in the adults
    • Slikker W, Mei N & Chen T (2004) N-Ethyl-N-nitrosourea (ENU) increased brain mutations in prenatal and neonatal mice but not in the adults. Toxicol Sci, 81(1): 112-120.
    • (2004) Toxicol Sci , vol.81 , Issue.1 , pp. 112-120
    • Slikker, W.1    Mei, N.2    Chen, T.3
  • 380
    • 0034691685 scopus 로고    scopus 로고
    • (200Oa) Interpretation of mutational spectra from different genes: Analyses of PhIP-induced mutational specificity in the lacI and cII transgenes from colon of Big Blue® rats
    • Stuart GR, Thorleifson E, Okochi E, de Boer JG, Ushijima T, Nagao M & Glickman BW (200Oa) Interpretation of mutational spectra from different genes: analyses of PhIP-induced mutational specificity in the lacI and cII transgenes from colon of Big Blue® rats. Mutat Res, 452: 101-121.
    • Mutat Res , vol.452 , pp. 101-121
    • Stuart, G.R.1    Thorleifson, E.2    Okochi, E.3    de Boer, J.G.4    Ushijima, T.5    Nagao, M.6    Glickman, B.W.7
  • 381
    • 0034650559 scopus 로고    scopus 로고
    • Prostate mutations in rats induced by the suspected human carcinogen 2-amino-1-methyl-6- phenylimidazo[4,5-b]pyridine
    • Stuart GR, Holcroft J, de Boer JG & Glickman BW (2000b) Prostate mutations in rats induced by the suspected human carcinogen 2-amino-1-methyl-6- phenylimidazo[4,5-b]pyridine. Cancer Res, 60: 266-268.
    • (2000) Cancer Res , vol.60 , pp. 266-268
    • Stuart, G.R.1    Holcroft, J.2    de Boer, J.G.3    Glickman, B.W.4
  • 383
    • 0022367064 scopus 로고
    • The mouse spot test. Evaluation of its performance in identifying chemical mutagens and carcinogens
    • Styles JA & Penman MG (1985) The mouse spot test. Evaluation of its performance in identifying chemical mutagens and carcinogens. Mutat Res, 154(3): 183-204.
    • (1985) Mutat Res , vol.154 , Issue.3 , pp. 183-204
    • Styles, J.A.1    Penman, M.G.2
  • 384
    • 0032933151 scopus 로고    scopus 로고
    • The relationship between mutant frequency and time in vivo: Simple predictions for any tissue, cell type, or mutagen
    • Sun B & Heddle JA (1999) The relationship between mutant frequency and time in vivo: simple predictions for any tissue, cell type, or mutagen. Mutat Res, 425: 179-183.
    • (1999) Mutat Res , vol.425 , pp. 179-183
    • Sun, B.1    Heddle, J.A.2
  • 386
    • 0027475874 scopus 로고
    • The concomitant detection of gene mutation and micronucleus induction by mitomycin C in vivo using lacZ transgenic mice
    • Suzuki T, Hayashi M, Sofuni T & Myhr BC (1993) The concomitant detection of gene mutation and micronucleus induction by mitomycin C in vivo using lacZ transgenic mice. Mutat Res, 285: 219-224.
    • (1993) Mutat Res , vol.285 , pp. 219-224
    • Suzuki, T.1    Hayashi, M.2    Sofuni, T.3    Myhr, B.C.4
  • 387
    • 0028198725 scopus 로고
    • Initial experiences and future directions for transgenic mouse mutation assays
    • Suzuki T, Hayashi M & Sofuni T (1994) Initial experiences and future directions for transgenic mouse mutation assays. Mutat Res, 307: 489-494.
    • (1994) Mutat Res , vol.307 , pp. 489-494
    • Suzuki, T.1    Hayashi, M.2    Sofuni, T.3
  • 388
    • 0343953723 scopus 로고
    • Diethylnitrosamine is mutagenic in liver but not in bone marrow of lacZ transgenic mice (Muta™Mouse)
    • Suzuki T, Hayashi M, Myhr B & Sofuni T (1995) Diethylnitrosamine is mutagenic in liver but not in bone marrow of lacZ transgenic mice (Muta™Mouse). Honyu Dobutsu Shiken Bunkakai Kaiho, 3(1): 33-39.
    • (1995) Honyu Dobutsu Shiken Bunkakai Kaiho , vol.3 , Issue.1 , pp. 33-39
    • Suzuki, T.1    Hayashi, M.2    Myhr, B.3    Sofuni, T.4
  • 391
    • 0031555314 scopus 로고    scopus 로고
    • A comparison of the genotoxicity of ethylnitrosourea and ethyl methanesulfonate in lacZ transgenic mice (Muta™Mouse)
    • Suzuki T, Hayashi M, Wang X, Yamamoto K, Ono T, Myhr BC & Sofuni T (1997) A comparison of the genotoxicity of ethylnitrosourea and ethyl methanesulfonate in lacZ transgenic mice (Muta™Mouse). Mutat Res, 395: 75-82.
    • (1997) Mutat Res , vol.395 , pp. 75-82
    • Suzuki, T.1    Hayashi, M.2    Wang, X.3    Yamamoto, K.4    Ono, T.5    Myhr, B.C.6    Sofuni, T.7
  • 392
    • 0032579152 scopus 로고    scopus 로고
    • In vivo mutagenesis by the hepatocarcinogen quinoline in the lacZ transgenic mouse: Evidence for its in vivo genotoxicity
    • Suzuki T, Miyata Y, Saeki K, Kawazoe Y, Hayashi M & Sofuni T (1998) In vivo mutagenesis by the hepatocarcinogen quinoline in the lacZ transgenic mouse: evidence for its in vivo genotoxicity. Mutat Res, 412: 161-166.
    • (1998) Mutat Res , vol.412 , pp. 161-166
    • Suzuki, T.1    Miyata, Y.2    Saeki, K.3    Kawazoe, Y.4    Hayashi, M.5    Sofuni, T.6
  • 393
    • 0032863852 scopus 로고    scopus 로고
    • Target organ and time-course in the mutagenicity of five carcinogens in Muta™Mouse: A summary report of the second collaborative study of the transgenic mouse mutation assay by the JEMS/MMS
    • Suzuki T, Itoh S, Nakajima M, Hachiya N & Hara T (1999a) Target organ and time-course in the mutagenicity of five carcinogens in Muta™Mouse: a summary report of the second collaborative study of the transgenic mouse mutation assay by the JEMS/MMS. Mutat Res, 444: 259-268.
    • (1999) Mutat Res , vol.444 , pp. 259-268
    • Suzuki, T.1    Itoh, S.2    Nakajima, M.3    Hachiya, N.4    Hara, T.5
  • 395
    • 0034946878 scopus 로고    scopus 로고
    • Just how does the cII selection system work in Muta Mouse?
    • Swiger RR (2001) Just how does the cII selection system work in Muta Mouse? Environ Mol Mutagen, 37(4): 290-296.
    • (2001) Environ Mol Mutagen , vol.37 , Issue.4 , pp. 290-296
    • Swiger, R.R.1
  • 397
    • 0032472895 scopus 로고    scopus 로고
    • Induction of somatic intrachromosomal recombination inversion events by cyclophosphamide in a transgenic mouse model
    • Sykes PJ, Hooker AM, Jacobs AK, Harrington CS, Kingsbury L & Morley AA (1998) Induction of somatic intrachromosomal recombination inversion events by cyclophosphamide in a transgenic mouse model. Mutat Res, 397: 209-219.
    • (1998) Mutat Res , vol.397 , pp. 209-219
    • Sykes, P.J.1    Hooker, A.M.2    Jacobs, A.K.3    Harrington, C.S.4    Kingsbury, L.5    Morley, A.A.6
  • 398
    • 0033151509 scopus 로고    scopus 로고
    • Inversion due to intrachromosomal recombination produced by carcinogens in a transgenic mouse model
    • Sykes PJ, Hooker AM & Morley AA (1999) Inversion due to intrachromosomal recombination produced by carcinogens in a transgenic mouse model. Mutat Res, 427: 1-9.
    • (1999) Mutat Res , vol.427 , pp. 1-9
    • Sykes, P.J.1    Hooker, A.M.2    Morley, A.A.3
  • 399
    • 0034753135 scopus 로고    scopus 로고
    • Effect of 900 MHz radiofrequency radiation exposure on intrachromosomal recombination in pKZ1 mice
    • Sykes PJ, McCallum BD, Bangay MJ, Hooker AM & Morley AA (2001) Effect of 900 MHz radiofrequency radiation exposure on intrachromosomal recombination in pKZ1 mice. Radiat Res, 156: 495-502.
    • (2001) Radiat Res , vol.156 , pp. 495-502
    • Sykes, P.J.1    McCallum, B.D.2    Bangay, M.J.3    Hooker, A.M.4    Morley, A.A.5
  • 400
    • 0037328065 scopus 로고    scopus 로고
    • Molecular characterization of mitomycin C-induced large deletions and tandem-base substitution in the bone marrow of gpt delta transgenic mice
    • Takeiri A, Mishima M, Tanaka K, Shioda A, Ueda O, Suzuki H, Inoue M, Masumura K & Nohmi T (2003) Molecular characterization of mitomycin C-induced large deletions and tandem-base substitution in the bone marrow of gpt delta transgenic mice. Chem Res Toxicol, 16: 171-179.
    • (2003) Chem Res Toxicol , vol.16 , pp. 171-179
    • Takeiri, A.1    Mishima, M.2    Tanaka, K.3    Shioda, A.4    Ueda, O.5    Suzuki, H.6    Inoue, M.7    Masumura, K.8    Nohmi, T.9
  • 401
    • 0027421332 scopus 로고
    • Comparison of somatic mutations in a transgenic versus host locus
    • Tao KS, Urlando C & Heddle JA (1993a) Comparison of somatic mutations in a transgenic versus host locus. Proc Natl Acad Sci USA, 90: 10681-10685.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 10681-10685
    • Tao, K.S.1    Urlando, C.2    Heddle, J.A.3
  • 402
    • 0027521327 scopus 로고
    • Mutagenicity of methyl methanesulfonate (MMS) in vivo at the Dlb-1 native locus and a lacI transgene
    • Tao KS, Urlando C & Heddle JA (1993b) Mutagenicity of methyl methanesulfonate (MMS) in vivo at the Dlb-1 native locus and a lacI transgene. Environ Mol Mutagen, 22: 293-296.
    • (1993) Environ Mol Mutagen , vol.22 , pp. 293-296
    • Tao, K.S.1    Urlando, C.2    Heddle, J.A.3
  • 407
    • 0028200469 scopus 로고
    • - transgenic mutation assay to DMN: Comparison with the corresponding Big Blue® (lacI) responses
    • - transgenic mutation assay to DMN: Comparison with the corresponding Big Blue® (lacI) responses. Mutat Res, 307: 169-173.
    • (1994) Mutat Res , vol.307 , pp. 169-173
    • Tinwell, H.1    Lefevre, P.A.2    Ashby, J.3
  • 408
    • 0028335008 scopus 로고
    • Mutation studies with dimethyl nitrosamine in young and old lacI transgenic mice
    • Tinwell H, Lefevre PA & Ashby J (1994b) Mutation studies with dimethyl nitrosamine in young and old lacI transgenic mice. Mutat Res, 307: 501-508.
    • (1994) Mutat Res , vol.307 , pp. 501-508
    • Tinwell, H.1    Lefevre, P.A.2    Ashby, J.3
  • 409
    • 0031709715 scopus 로고    scopus 로고
    • Relative activities of methyl methanesulphonate (MMS) as a genotoxin, clastogen and gene mutagen to the liver and bone marrow of Muta™Mouse mice
    • Tinwell H, Lefevre PA & Ashby J (1998) Relative activities of methyl methanesulphonate (MMS) as a genotoxin, clastogen and gene mutagen to the liver and bone marrow of Muta™Mouse mice. Environ Mol Mutagen, 32: 163-172.
    • (1998) Environ Mol Mutagen , vol.32 , pp. 163-172
    • Tinwell, H.1    Lefevre, P.A.2    Ashby, J.3
  • 410
    • 0032808216 scopus 로고    scopus 로고
    • Effect of mitogenic or regenerative cell proliferation on lacZ mutant frequency in the liver of Muta™Mice treated with 5,9-dimethyldibenzo[c,g]carbazole
    • Tombolan F, Renault D, Brault D, Guffroy M, Périn F & Thybaud V (1999a) Effect of mitogenic or regenerative cell proliferation on lacZ mutant frequency in the liver of Muta™Mice treated with 5,9-dimethyldibenzo[c,g]carbazole. Carcinogenesis, 20: 1357-1362.
    • (1999) Carcinogenesis , vol.20 , pp. 1357-1362
    • Tombolan, F.1    Renault, D.2    Brault, D.3    Guffroy, M.4    Périn, F.5    Thybaud, V.6
  • 411
    • 0032921794 scopus 로고    scopus 로고
    • Kinetics of induction of DNA adducts, cell proliferation and gene mutations in the liver of Muta™Mice treated with 5,9-dimethyldibenzo[c,g]carbazole
    • Tombolan F, Renault D, Brault D, Guffroy M, Perin-Roussel O, Perin F & Thybaud V (1999b) Kinetics of induction of DNA adducts, cell proliferation and gene mutations in the liver of Muta™Mice treated with 5,9-dimethyldibenzo[c,g]carbazole. Carcinogenesis, 20(1): 125-132.
    • (1999) Carcinogenesis , vol.20 , Issue.1 , pp. 125-132
    • Tombolan, F.1    Renault, D.2    Brault, D.3    Guffroy, M.4    Perin-Roussel, O.5    Perin, F.6    Thybaud, V.7
  • 412
    • 2342594381 scopus 로고    scopus 로고
    • No-effect level in the mutagenic activity of the drug cyproterone acetate in rat liver. Part I: Single dose treatment
    • Topinka J, Oesterle D, Reimann R & Wolff T (2004a) No-effect level in the mutagenic activity of the drug cyproterone acetate in rat liver. Part I: Single dose treatment. Mutat Res, 550(1-2): 89-99.
    • (2004) Mutat Res , vol.550 , Issue.1-2 , pp. 89-99
    • Topinka, J.1    Oesterle, D.2    Reimann, R.3    Wolff, T.4
  • 413
    • 2342654438 scopus 로고    scopus 로고
    • No-effect level in the mutagenic activity of the drug cyproterone acetate in rat liver. Part II: Multiple dose treatment
    • Topinka J, Oesterle D, Reimann R & Wolff T (2004b) No-effect level in the mutagenic activity of the drug cyproterone acetate in rat liver. Part II: Multiple dose treatment. Mutat Res, 550(1-2): 101-108.
    • (2004) Mutat Res , vol.550 , Issue.1-2 , pp. 101-108
    • Topinka, J.1    Oesterle, D.2    Reimann, R.3    Wolff, T.4
  • 415
    • 0017823520 scopus 로고
    • The evaluation of sixteen carcinogens in the rat using the micronucleus test
    • Trzos RJ, Petzold GL, Brunden MN & Swenberg JA (1978) The evaluation of sixteen carcinogens in the rat using the micronucleus test. Mutat Res, 58: 79-86.
    • (1978) Mutat Res , vol.58 , pp. 79-86
    • Trzos, R.J.1    Petzold, G.L.2    Brunden, M.N.3    Swenberg, J.A.4
  • 418
    • 0034915403 scopus 로고    scopus 로고
    • The male rat carcinogens limonene and sodium saccharin are not mutagenic to male Big Blue rats
    • Turner SD, Tinwell H, Piegorsch W, Schmezer P & Ashby J (2001) The male rat carcinogens limonene and sodium saccharin are not mutagenic to male Big Blue rats. Mutagenesis, 16(4): 329-332.
    • (2001) Mutagenesis , vol.16 , Issue.4 , pp. 329-332
    • Turner, S.D.1    Tinwell, H.2    Piegorsch, W.3    Schmezer, P.4    Ashby, J.5
  • 419
    • 0023858244 scopus 로고
    • Further debate of testing strategies
    • Tweats DJ & Gatehouse DG (1988) Further debate of testing strategies. Mutagenesis, 3(2): 95-102.
    • (1988) Mutagenesis , vol.3 , Issue.2 , pp. 95-102
    • Tweats, D.J.1    Gatehouse, D.G.2
  • 421
    • 0036162868 scopus 로고    scopus 로고
    • Characterization of mutant spectra generated by a forward mutational assay for gene A of ΦX174 from ENU-treated transgenic mouse embryonic cell line PX-2
    • Valentine CR, Montgomery BA, Miller SG, Delongchamp RR, Fane BA & Malling HV (2002) Characterization of mutant spectra generated by a forward mutational assay for gene A of ΦX174 from ENU-treated transgenic mouse embryonic cell line PX-2. Environ Mol Mutagen, 39: 55-68.
    • (2002) Environ Mol Mutagen , vol.39 , pp. 55-68
    • Valentine, C.R.1    Montgomery, B.A.2    Miller, S.G.3    Delongchamp, R.R.4    Fane, B.A.5    Malling, H.V.6
  • 423
    • 0031815614 scopus 로고    scopus 로고
    • Gene-mutation assay in lambda lacZ transgenic mice: Comparison of lacZ with endogenous genes in splenocytes and small intestinal epithelium
    • van Delft JH, Bergmans A, van Dam FJ, Tates AD, Howard L, Winton DJ & Baan RA (1998) Gene-mutation assay in lambda lacZ transgenic mice: comparison of lacZ with endogenous genes in splenocytes and small intestinal epithelium. Mutat Res, 415: 85-96.
    • (1998) Mutat Res , vol.415 , pp. 85-96
    • van Delft, J.H.1    Bergmans, A.2    van Dam, F.J.3    Tates, A.D.4    Howard, L.5    Winton, D.J.6    Baan, R.A.7
  • 426
    • 0030580952 scopus 로고    scopus 로고
    • Studies on the genotoxicity of tamoxifen citrate in mouse bone marrow cells
    • Vijayalaxmi KK & Rai SP (1996) Studies on the genotoxicity of tamoxifen citrate in mouse bone marrow cells. Mutat Res, 368(2): 109-114.
    • (1996) Mutat Res , vol.368 , Issue.2 , pp. 109-114
    • Vijayalaxmi, K.K.1    Rai, S.P.2
  • 428
    • 0031592241 scopus 로고    scopus 로고
    • Transgenic mouse models for studying mutations in vivo: Applications in aging research
    • Vijg J, Dolle ME, Martus HJ & Boerrigter ME (1997) Transgenic mouse models for studying mutations in vivo: applications in aging research. Mech Ageing Dev, 99: 257-271.
    • (1997) Mech Ageing Dev , vol.99 , pp. 257-271
    • Vijg, J.1    Dolle, M.E.2    Martus, H.J.3    Boerrigter, M.E.4
  • 429
    • 0034917463 scopus 로고    scopus 로고
    • Pharmacological coal tar induces G:C to T:A transversion mutations in the skin of Muta Mouse
    • Vogel U, Thein N, Moller P & Wallin H (2001) Pharmacological coal tar induces G:C to T:A transversion mutations in the skin of Muta Mouse. Pharmacol Toxicol, 89(1): 30-34.
    • (2001) Pharmacol Toxicol , vol.89 , Issue.1 , pp. 30-34
    • Vogel, U.1    Thein, N.2    Moller, P.3    Wallin, H.4
  • 430
    • 0032697598 scopus 로고    scopus 로고
    • Mutagenesis induced by oral carcinogens in lacZ mouse (Muta™Mouse) tongue and other oral tissues
    • von Pressentin MdM, Kosinska W & Guttenplan JB (1999) Mutagenesis induced by oral carcinogens in lacZ mouse (Muta™Mouse) tongue and other oral tissues. Carcinogenesis, 20: 2167-2170.
    • (1999) Carcinogenesis , vol.20 , pp. 2167-2170
    • von Pressentin, M.M.1    Kosinska, W.2    Guttenplan, J.B.3
  • 431
    • 13644253379 scopus 로고    scopus 로고
    • Mutagenicity testing with transgenic mice. Part I: Comparison with the mouse bone marrow micronucleus test
    • Wahnschaffe U, Bitsch A, Kielhorn J & Mangelsdorf I (2005a) Mutagenicity testing with transgenic mice. Part I: Comparison with the mouse bone marrow micronucleus test. J Carcinogen, 4(3): 1-14.
    • (2005) J Carcinogen , vol.4 , Issue.3 , pp. 1-14
    • Wahnschaffe, U.1    Bitsch, A.2    Kielhorn, J.3    Mangelsdorf, I.4
  • 432
    • 13644265958 scopus 로고    scopus 로고
    • Mutagenicity testing with transgenic mice. Part II: Comparison with the mouse spot test
    • Wahnschaffe U, Bitsch A, Kielhom J & Mangelsdorf I (2005b) Mutagenicity testing with transgenic mice. Part II: Comparison with the mouse spot test. J Carcinogen, 4(4): 1-8.
    • (2005) J Carcinogen , vol.4 , Issue.4 , pp. 1-8
    • Wahnschaffe, U.1    Bitsch, A.2    Kielhom, J.3    Mangelsdorf, I.4
  • 434
    • 0030744798 scopus 로고    scopus 로고
    • In vivo mutagenicity of ethylene oxide at the hprt locus in T-lymphocytes of B6C3F1 lacI transgenic mice following inhalation exposure
    • Walker VE, Sisk SC, Upton PB, Wong BA & Recio L (1997) In vivo mutagenicity of ethylene oxide at the hprt locus in T-lymphocytes of B6C3F1 lacI transgenic mice following inhalation exposure. Mutat Res, 392: 211-222.
    • (1997) Mutat Res , vol.392 , pp. 211-222
    • Walker, V.E.1    Sisk, S.C.2    Upton, P.B.3    Wong, B.A.4    Recio, L.5
  • 436
    • 0033402830 scopus 로고    scopus 로고
    • Relationship between exposure, cell loss and proliferation, and manifestation of Hprt mutant T cells following treatment of preweanling, weanling, and adult male mice with N-ethyl-N-nitrosourea
    • Walker VE, Jones IM, Crippen TL, Meng Q, Walker DM, Bauer MJ, Reilly AA, Tates AD, Nakamura J, Upton PB & Skopek TR (1999b) Relationship between exposure, cell loss and proliferation, and manifestation of Hprt mutant T cells following treatment of preweanling, weanling, and adult male mice with N-ethyl-N-nitrosourea. Mutat Res, 431: 371-388.
    • (1999) Mutat Res , vol.431 , pp. 371-388
    • Walker, V.E.1    Jones, I.M.2    Crippen, T.L.3    Meng, Q.4    Walker, D.M.5    Bauer, M.J.6    Reilly, A.A.7    Tates, A.D.8    Nakamura, J.9    Upton, P.B.10    Skopek, T.R.11
  • 437
    • 8444225729 scopus 로고    scopus 로고
    • Time course of cII gene mutant manifestation in the liver, spleen, and bone marrow of N-ethyl-N-nitrosourea-treated Big Blue® transgenic mice
    • Wang J, Liu X, Heflich RH & Chen T (2004) Time course of cII gene mutant manifestation in the liver, spleen, and bone marrow of N-ethyl-N-nitrosourea-treated Big Blue® transgenic mice. Toxicol Sci, 82(1): 124-128.
    • (2004) Toxicol Sci , vol.82 , Issue.1 , pp. 124-128
    • Wang, J.1    Liu, X.2    Heflich, R.H.3    Chen, T.4
  • 439
    • 4344588836 scopus 로고    scopus 로고
    • Spontaneous and induced chromosomal damage and mutations in Bloom Syndrome mice
    • Wang Y & Heddle JA (2004) Spontaneous and induced chromosomal damage and mutations in Bloom Syndrome mice. Mutat Res, 554(1-2): 131-137.
    • (2004) Mutat Res , vol.554 , Issue.1-2 , pp. 131-137
    • Wang, Y.1    Heddle, J.A.2
  • 440
    • 0242331212 scopus 로고    scopus 로고
    • Transgenic and knockout mice for DNA repair functions in carcinogenesis and mutagenesis
    • Wijnhoven SW & van Steeg H (2003) Transgenic and knockout mice for DNA repair functions in carcinogenesis and mutagenesis. Toxicology, 193: 171-187.
    • (2003) Toxicology , vol.193 , pp. 171-187
    • Wijnhoven, S.W.1    van Steeg, H.2
  • 441
    • 0021912230 scopus 로고    scopus 로고
    • Wild D, Gocke E, Harnasch D, Kaiser G & King MT (1985) Differential mutagenic activity of IQ (2-amino-3-methylimidazo[4,5-f]quinoline) in Salmonella typhimurium strains in vitro and in vivo, in Drosophila, and in mice. Mutat Res, 156: 93-102.
    • Wild D, Gocke E, Harnasch D, Kaiser G & King MT (1985) Differential mutagenic activity of IQ (2-amino-3-methylimidazo[4,5-f]quinoline) in Salmonella typhimurium strains in vitro and in vivo, in Drosophila, and in mice. Mutat Res, 156: 93-102.
  • 443
    • 0030926726 scopus 로고    scopus 로고
    • Analysis of the mutagenic potential of ENU and MMS in germ cells of male C57BL/6 lacI transgenic mice
    • Winegar RA, Carr G & Mirasalis JC (1997) Analysis of the mutagenic potential of ENU and MMS in germ cells of male C57BL/6 lacI transgenic mice. Mutat Res, 388: 175-178.
    • (1997) Mutat Res , vol.388 , pp. 175-178
    • Winegar, R.A.1    Carr, G.2    Mirasalis, J.C.3
  • 444
    • 0023894101 scopus 로고
    • A clonal marker induced by mutation in mouse intestinal epithelium
    • Winton DJ, Blount MA & Ponder BAJ (1988) A clonal marker induced by mutation in mouse intestinal epithelium. Nature, 333: 463-466.
    • (1988) Nature , vol.333 , pp. 463-466
    • Winton, D.J.1    Blount, M.A.2    Ponder, B.A.J.3
  • 445
    • 0025599895 scopus 로고
    • Mutagenesis of mouse intestine in vivo using the Dlb-1 specific locus test: Studies with 1,2-dimethylhydrazine, dimethylnitrosamine, and the dietary mutagen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline
    • Winton DJ, Gooderham NJ, Boobos AR, Davies DS & Ponder BAJ (1990) Mutagenesis of mouse intestine in vivo using the Dlb-1 specific locus test: studies with 1,2-dimethylhydrazine, dimethylnitrosamine, and the dietary mutagen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline. Cancer Res, 50: 7992-7996.
    • (1990) Cancer Res , vol.50 , pp. 7992-7996
    • Winton, D.J.1    Gooderham, N.J.2    Boobos, A.R.3    Davies, D.S.4    Ponder, B.A.J.5
  • 446
    • 0035697779 scopus 로고    scopus 로고
    • Dose dependent induction of DNA adducts, gene mutations and cell proliferation by the antiandrogenic drug cyproterone acetate in rat liver
    • Wolff T, Topinka J, Demi E, Oesterle D & Schwarz LR (2001) Dose dependent induction of DNA adducts, gene mutations and cell proliferation by the antiandrogenic drug cyproterone acetate in rat liver. Adv Exp Med Biol, 500: 678-696.
    • (2001) Adv Exp Med Biol , vol.500 , pp. 678-696
    • Wolff, T.1    Topinka, J.2    Demi, E.3    Oesterle, D.4    Schwarz, L.R.5
  • 447
    • 1842579629 scopus 로고    scopus 로고
    • In vivo mutagenicity of benzo[f]quinoline, benzo[h]quinoline, and 1,7-phenanthroline using the lacZ transgenic mice
    • Yamada K, Suzuki T, Kohara A, Hayashi M, Mizutani T & Saeki K (2004) In vivo mutagenicity of benzo[f]quinoline, benzo[h]quinoline, and 1,7-phenanthroline using the lacZ transgenic mice. Mutat Res, 559(1-2): 83-95.
    • (2004) Mutat Res , vol.559 , Issue.1-2 , pp. 83-95
    • Yamada, K.1    Suzuki, T.2    Kohara, A.3    Hayashi, M.4    Mizutani, T.5    Saeki, K.6
  • 448
    • 0036042258 scopus 로고    scopus 로고
    • Sex-specific induction of mutations by PhIP in the kidney of male and female rats and its modulations by conjugated linoleic acid
    • Yang H, Glickman B & de Boer JG (2002) Sex-specific induction of mutations by PhIP in the kidney of male and female rats and its modulations by conjugated linoleic acid. Environ Mol Mutagen, 40(2): 116-121.
    • (2002) Environ Mol Mutagen , vol.40 , Issue.2 , pp. 116-121
    • Yang, H.1    Glickman, B.2    de Boer, J.G.3
  • 450
    • 0343762013 scopus 로고    scopus 로고
    • Intestinal mutagenicity of two carcinogenic food mutagens in transgenic mice: 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and amino(α) carboline
    • Zhang XB, Felton JS, Tucker JD, Urlando C & Heddle JA (1996) Intestinal mutagenicity of two carcinogenic food mutagens in transgenic mice: 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and amino(α) carboline. Carcinogenesis, 17: 2259-2265.
    • (1996) Carcinogenesis , vol.17 , pp. 2259-2265
    • Zhang, X.B.1    Felton, J.S.2    Tucker, J.D.3    Urlando, C.4    Heddle, J.A.5
  • 451
    • 0032907234 scopus 로고    scopus 로고
    • Comparison of mutant frequencies at the transgenic λ LacI and cII/cI loci in control and ENU-treated Big Blue® mice
    • Zimmer DM, Harbach PR, Mattes WB & Aaron CS (1999) Comparison of mutant frequencies at the transgenic λ LacI and cII/cI loci in control and ENU-treated Big Blue® mice. Environ Mol Mutagen, 33: 249-256.
    • (1999) Environ Mol Mutagen , vol.33 , pp. 249-256
    • Zimmer, D.M.1    Harbach, P.R.2    Mattes, W.B.3    Aaron, C.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.