Hepatic gene mutations induced in Big Blue(TM) rats by both the potent rat liver azo-carcinogen 6BT and its reported noncarcinogenic analogue 5BT

Environmental and Molecular Mutagenesis

Volumn 34, Issue 2-3, 1999, Pages 148-153

  Fletcher, K ^a   Soames, A R ^a   Tinwell, H ^a   Lefevre, P A ^a   Ashby, J ^a  

^a ASTRAZENECA   (United Kingdom)

Author keywords

5BT; 6BT; Big Blue(TM) rat; Carcinogenicity; Hepatic gene mutation

Indexed keywords

AZO COMPOUND; CARCINOGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOASSAY; CARCINOGENICITY; CELL PROLIFERATION; CONTROLLED STUDY; DNA DAMAGE; GENE MUTATION; LIVER CELL; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; TRANSGENIC MOUSE;

ANIMALS; BENZOTHIAZOLES; CARCINOGENS; CELL DIVISION; LIVER; LIVER NEOPLASMS, EXPERIMENTAL; MALE; MUTATION; P-DIMETHYLAMINOAZOBENZENE; RATS; THIAZOLES;

EID: 0032725131     PISSN: 08936692     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2280(1999)34:2/3<148::AID-EM14>3.0.CO;2-T     Document Type: Article

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