Multiple organ mutation in the lacZ transgenic mouse (Muta(TM) Mouse) 6 months after oral treatment (5 days) with benzo[a]pyrene

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 426, Issue 1, 1999, Pages 71-77

  Hakura, Atsushi ^a   Tsutsui, Yoshie ^b   Sonoda, Jiro ^b   Mikami, Takashi ^a   Tsukidate, Kazuo ^b   Sagami, Fumio ^a   Kerns, William D ^c  

^a Drug Safety Research Laboratories   (Japan)

^b Drug Safety Research Laboratories   (Japan)

^c EISAI RESEARCH INSTITUTE   (United States)

Author keywords

Benzo a pyrene; Carcinogenicity; Cell proliferation; In vivo mutation; Muta(TM) Mouse; Stem cell

Indexed keywords

BENZO[A]PYRENE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CARCINOGENICITY; CELL PROLIFERATION; COLON; CONTROLLED STUDY; FORESTOMACH; LIVER; LUNG; MALE; MOUSE; MUTANT; MUTATION; MUTATION RATE; NONHUMAN; PRIORITY JOURNAL; SPLEEN; STEM CELL; TRANSGENIC MOUSE; TUMOR;

ADMINISTRATION, ORAL; ANIMALS; BENZO(A)PYRENE; CARCINOMA, SQUAMOUS CELL; LAC OPERON; LUNG; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED DBA; MICE, TRANSGENIC; MUTATION; PAPILLOMA; SPLEEN; STOMACH;

MUS MUSCULUS;

EID: 0033007949     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(99)00046-9     Document Type: Article

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