Methyl bromide causes DNA methylation in rats and mice but fails to induce somatic mutations in λlacZ transgenic mice

Cancer Letters

Volumn 135, Issue 1, 1998, Pages 21-27

  Pletsa, Vassiliki ^a   Steenwinkel, Marie José S T ^b   Van Delft, Joost H M ^b   Baan, Robert A ^b   Kyrtopoulos, Soterios A ^a  

^a INSTITUTE OF BIOLOGY   (Greece)

^b TNO   (Netherlands)

Author keywords

Methylating agents; N7 methylguanine; O6 Alkylguanine DNA alkyltransferase; O6 Methylguanine; Pesticides; Somatic mutation

Indexed keywords

6 O ALKYLGUANINE DNA ALKYLTRANSFERASE; 6 O METHYLGUANINE; 7 METHYLGUANINE; METHYL BROMIDE; PESTICIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MARROW; CONTROLLED STUDY; DNA ADDUCT; DNA METHYLATION; FEMALE; GENE MUTATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SOMATIC MUTATION; STOMACH; TISSUE DISTRIBUTION; TRANSGENIC MOUSE;

ANIMALS; DNA ADDUCTS; DNA METHYLATION; DOSE-RESPONSE RELATIONSHIP, DRUG; GUANINE; HYDROCARBONS, BROMINATED; LAC OPERON; MALE; MICE; MICE, TRANSGENIC; MUTAGENESIS; MUTAGENS; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; RATS; RATS, SPRAGUE-DAWLEY;

MUS MUSCULUS;

EID: 0032416598     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(98)00262-6     Document Type: Article

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