Hprt mutant frequency and molecular analysis of Hprt mutations in rats treated with mutagenic carcinogens

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 431, Issue 2, 1999, Pages 389-395

  Casciano, Daniel A ^a,b   Aidoo, Anane ^a   Chen, Tao ^a,c   Mittelstaedt, Roberta A ^a   Manjanatha, Mugimane G ^a   Heflich, Robert H ^a,b  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^c U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

7,12 dimethylbenzp a anthracene; DNA sequencing; Hprt; Mutation frequency; Mutational spectra; N ethyl N nitrosourea; Rat lymphocyte assay; Thiotepa

Indexed keywords

HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE;

ARTICLE; CARCINOGENESIS; CHEMICAL MUTAGENESIS; DNA SEQUENCE; GENE FREQUENCY; MUTATION RATE; NONHUMAN; PRIORITY JOURNAL; RAT; SEQUENCE ANALYSIS;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ANIMALS; ANIMALS, GENETICALLY MODIFIED; CARCINOGENS; CELL CULTURE TECHNIQUES; CELLS, CULTURED; ELECTROPHORESIS; ETHYLNITROSOUREA; FEMALE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; LYMPHOCYTES; MUTAGENICITY TESTS; MUTAGENS; MUTATION; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; THIOTEPA; TRIETHYLENEPHOSPHORAMIDE;

EID: 0033396678     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(99)00181-5     Document Type: Article

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