Single cell gel/comet assay: Guidelines for in vitro and in vivo genetic toxicology testing

Environmental and Molecular Mutagenesis

Volumn 35, Issue 3, 2000, Pages 206-221

  Tice, R R ^a   Agurell, E ^b   Anderson, D ^c   Burlinson, B ^d   Hartmann, A ^e   Kobayashi, H ^f   Miyamae, Y ^g   Rojas, E ^h   Ryu, J C ⁱ   Sasaki, Y F ^j  

^a INTEGRATED LABORATORY SYSTEMS   (United States)

^b ASTRAZENECA R AND D   (Sweden)

^c BIBRA INTERNATIONAL   (United Kingdom)

^d GLAXOSMITHKLINE   (United Kingdom)

^e NOVARTIS PHARMA AG   (Switzerland)

^f SHISEIDO RESEARCH CENTER   (Japan)

^g ASTELLAS PHARMA INC   (Japan)

^h INSTITUTO DE INVESTIGACIONES BIOMÉDICAS   (Mexico)

ⁱ Korea Institute of Science and Technology   (South Korea)

^j HACHINOHE NATIONAL COLLEGE OF TECHNOLOGY   (Japan)

more..

Author keywords

Alkaline electrophoresis; Comet assay; DNA damage; Genotoxicity; Single cell gel assay

Indexed keywords

SINGLE STRANDED DNA;

ANIMAL CELL; BINDING SITE; CONFERENCE PAPER; CONTROLLED STUDY; DNA DAMAGE; DNA STRAND BREAKAGE; ELECTROPHORESIS; EXCISION REPAIR; GENETIC TOXICOLOGY; MOUSE; NONHUMAN; PRACTICE GUIDELINE; RAT; SCORING SYSTEM; TOXICITY TESTING;

ANIMALS; BIOTRANSFORMATION; CELL LINE; COMET ASSAY; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, AGAR GEL; FEMALE; GUIDELINES; HUMANS; MALE; MICE; MUTAGENS; RATS;

ANIMALIA;

EID: 0034037611     PISSN: 08936692     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2280(2000)35:3<206::AID-EM8>3.0.CO;2-J     Document Type: Conference Paper

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