A novel positive detection system of in vivo mutations in rpsL (strA) transgenic mice

Mutation Research - Environmental Mutagenesis and Related Subjects

Volumn 360, Issue 1, 1996, Pages 1-14

  Gondo, Yoichi ^a,b,c   Shioyama, Yoshiyuki ^a   Nakao, Kazuki ^a   Katsuki, Motoya ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c TOKAI UNIVERSITY   (Japan)

Author keywords

Mutation assay, in vivo; Mutation assay, positive selection; Plasmid shuttle vector; rpsL gene; Transgenic mouse

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; ESCHERICHIA COLI; IN VIVO STUDY; MOUSE; MUTAGEN TESTING; MUTATION; NONHUMAN; PLASMID; PRIORITY JOURNAL; SHUTTLE VECTOR; TRANSGENIC MOUSE;

ANIMALIA; ESCHERICHIA COLI; MUS MUSCULUS;

EID: 0029947527     PISSN: 01651161     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-1161(96)90231-9     Document Type: Article

References (35)

1. Brilliant, M.H., Y. Gondo and E.M. Eicher (1991) Direct molecular identification of the mouse pink-eyed unstable mutation by genome scanning, Science, 252, 566-569.
2. Burkhart, J.G., B.A. Burkhart, K.S. Sampson and H.V. Malling (1993) ENU-induced mutagenesis at a single A:T base pair in transgenic mice containing ΦX174, Mutation Res., 292, 69-81.
3. Church, G.M. and W. Gilbert (1984) Genomic sequencing, Proc. Natl. Acad. Sci. USA, 1991-1995.
4. Couto, L.B., I. Chaudhuri, B.A. Donahue, B. Demple and J.M. Essigmann (1989) Separation of the SOS-dependent and SOS-independent components of alkylating-agent mutagenesis, J. Bacteriol., 171, 4170-4177.
5. Dean, D. (1981) A plasmid cloning vector for the direct selection of strains carrying recombinant plasmids, Gene, 15, 99-102.
6. Dycaico, M.J., G.S. Provost, P.L. Kretz, S.L. Ransom, J.C. Moores, J.M. Short (1994) The use of shuttle vectors for mutation analysis in transgenic mice and rats, Mutation Res., 307, 461-478.
7. Gondo, Y., K. Nakao, M. Takahashi, Y. Ikeda, Y. Motegi, A. Takeshita and M. Katsuki (1993) Development of hypersensitive in vivo test of carcinogenicity by using transgenic mice (Japanese), Environ. Mutation Res. Commun., 15, 39-49.
8. Gondo, Y., K. Nakamura, K. Nakao, T. Sasaoka, K. Ito, M. Kimura and M. Katsuki (1994a) Gene replacement of the p53 gene with the lacZ gene in mouse embryonic stem cells and mice by using two steps of homologous recombination. Biochem. Biophys. Res. Commun., 202, 830-837.
9. Gondo, Y., Y. Ikeda, Y. Motegi, A. Takeshita, M. Takahashi, K. Nakao and M. Katsuki (1994b) Development of new risk assessment test by using transgenic mice (Japanese). Environ. Mutation Res. Commun., 16, 53-65.
10. Gordon, J.W., G.A. Scangos, D.J. Plotkin, J.A. Barbosa and F.H. Ruddle (1980) Genetic transformation of mouse embryos by microinjection of purified DNA, Proc. Natl. Acad. Sci. USA, 77, 7380-7384.
11. Gossen, J.A., W.J.F. de Leeuw, C.H.T. Tan. E.C. Zwarthoff, F. Berends, P.H.M. Lohman, D.L. Knook and J. Vijg (1989) Efficient rescue of integrated shuttle vectors from transgenic mice: a model for studying mutations in vivo, Proc. Natl. Acad. Sci. USA, 86, 7971-7975.
12. Gossen, J.A., W.J.F. de Leeuw, A. Verwest, P.H.M. Lohman and J. Vijg (1991) High somatic mutation frequencies in a lacZ transgene integrated on the mouse X-chromosome, Mutation Res., 250, 423-429.
13. Gossen, J.A., W.J.F. de Leeuw, A.C. Molijn and J. Vijg (1993) Plasmid rescue from transgenic mouse DNA using lacI represser protein conjugated to magnetic beads, BioTechniques, 14, 624-629.
14. Gossen, J.A., W.J.F. de Leeuw and J. Vijg (1994) LacZ transgenic mouse models: their application in genetic toxicology, Mutation Res., 307, 451-459.
15. Hashimoto-Gotoh, T., A. Kume, W. Masahashi, S. Takeshita and A. Fukuda (1986) Improved vector, pHSG664, for direct streptomycin-resistance selection: cDNA cloning with G: C-tailing procedure and subcloning of double-digest DNA fragments, Gene, 41, 125-128.
16. Kohler, S.W., G.S. Provost, A. Fieck, P.L. Kretz, W.O. Bullock, D.L. Putman, J.A. Sorge, J.M. Short (1991a) Analysis of spontaneous and induced mutations in transgenic mice using a lambda ZAP /lacI shuttle vector, Environ. Mol. Mutagenesis, 18, 316-321.
17. Kohler, S.W., G.S. Provost, A. Fieck, P.L. Kretz, W.O. Bullock, J.A. Sorge, D.L. Putman and J.M. Short (1991b) Spectra of spontaneous and mutagen-induced mutations in the lacI gene in transgenic mice, Proc. Natl. Acad. Sci. USA, 88, 7958-7962.
18. Kume-Iwaki, A., W. Masahashi and T. Hashimoto-Gotoh (1987) Construction of a streptomycin-direct selection plasmid vector having twenty six unique cloning sites, Mol. Gen. (Life Sci. Adv.), 6, 109-112.
19. Lederberg, J. (1951) Streptomycin resistance: a genetically recessive mutation, J. Bacteriol., 61, 549-550.
20. Mo. J.-Y., Maki, H. and Sekiguchi, M. (1991) Mutational specificity of the dnaE173 mutator associated with a defect in the catalytic subunit of DNA polymerase III of Escherichia coli. J. Mol. Biol., 222, 925-936.
21. Oka, A., H. Sugisaki and M. Takanami (1981) Nucleotide sequence of the kanamycin resistance transposon Tn 903, J. Mol. Biol., 147, 217-226.
22. Piegorsch, W.W., A.C. Lockhart, B.H. Margolin, K.R. Tindall, N.J. Gorelick, J.M. Short, G.J. Carr, E.D. Thompson and M.D. Shelby (1994) Sources of variability in data from a lacI transgenic mouse mutation assay. Environ. Mol. Mutagen., 23, 17-31.
23. Post, L.E., A.E. Arfsten, F. Reusser and M. Nomura (1978) DNA sequences of promoter regions for the str and spc ribosomal protein operons in E. coli, Cell, 15, 215-229.
24. Saitoh, A., M. Kimura, R. Takahashi, M. Yokoyama, T. Nomura, M. Izawa, T. Sekiya, S. Nishimura and M. Katsuki (1990) Most tumors in transgenic mice with human c-Ha-ras gene contained somatically activated transgenes, Oncogene, 5, 1195-1200.
25. Sambrook, J., Fritsch, E.F. and Maniatis, T. (1989) Molecular Cloning, A Laboratory Manual, 2nd Edn.
26. Schmezer, P., C. Eckert and U.M. Liegibel (1994) Tissue-specific induction of mutations by streptozotocin in vivo. Mutation Res., 307, 495-499.
27. Short, J., S.W. Kohler, W.D. Huse and J.A. Sorge (1988) A transgenic model for the identification of genetic lesions, Fed. Proc., 8515a.
28. 10 E. coli transformants/ μg, Focus, 12, 38-40.
29. Summers, W.C., P.M. Glazer and D. Malkevich (1989) Lambda phage shuttle vectors for analysis of mutations in mammalian cells in culture and in transgenic mice. Mutation Res., 220, 263-268.
30. Suzuki, T., M. Hayashi, T. Sofuni (1994) Initial experiences and future directions for transgenic mouse mutation assays. Mutation Res., 307, 489-494.
31. Tinwell, H., P.A. Lefevre and J. Ashby (1994) Mutation studies with dimethyl nitrosoamine in young and old lacI transgenic mice. Mutation Res., 307, 501-508.
32. S-enforcement cloning vectors with a synthetic rpsL gene, Gene, 121, 25-33.
33. Vieira, J. and J. Messing (1982) The pUC plasmids. an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers, Gene, 19, 259-268.
34. Whittingham, D.G., S.P. Leibo and P. Mazur (1972) Survival of mouse embryos frozen to - 196°C and - 269°C. Science, 178, 411-414.
35. Winegar, R.A., L.H. Lutze, J.D. Hamer, K.G. O'Loughlin and J.C. Mirsalis (1994) Radiation-induced point mutations, deletions and micronuclei in lacI transgenic mice. Mutation Res., 307, 479-487.