Relationships between exposure, cell loss and proliferation, and manifestation of Hprt mutant T cells following treatment of preweanling, weanling, and adult male mice with N-ethyl-N-nitrosourea

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 431, Issue 2, 1999, Pages 371-388

  Walker, Vernon E ^a,b,c   Jones, Irene M ^d   Crippen, Tawni L ^d   Meng, Quanxin ^b   Walker, Dale M ^b   Bauer, Michael J ^c   Reilly, Andrew A ^b,c   Tates, Ad D ^e   Nakamura, Jun ^a   Upton, Patricia B ^a   Skopek, Thomas R ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b WADSWORTH CENTER   (United States)

^c STATE UNIVERSITY OF NEW YORK   (United States)

^d LAWRENCE LIVERMORE NATIONAL LABORATORY   (United States)

^e LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Ethylnitrosourea; Hprt; Lymphocytes; Mice; Molecular dosimetry; Mutagenicity

Indexed keywords

ETHYLNITROSOUREA;

ANIMAL CELL; ARTICLE; GENE FREQUENCY; GENE MUTATION; GENOTOXICITY; LYMPHOCYTE CLONE; LYMPHOCYTE DEPLETION; LYMPHOCYTE PROLIFERATION; MALE; MOUSE; MUTATION RATE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE;

AGE FACTORS; ALKYLATING AGENTS; ANIMALS; CELL DIVISION; ETHYLNITROSOUREA; FEMALE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; MUTAGENS; MUTATION; SPLEEN; T-LYMPHOCYTES; THYMUS GLAND; WEANING;

EID: 0033402830     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(99)00180-3     Document Type: Article

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