Interpretation of mutational spectra from different genes: Analyses of PhIP-induced mutational specificity in the lacI and cII transgenes from colon of Big Blue® rats

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 452, Issue 1, 2000, Pages 101-121

  Stuart, Gregory R ^a   Thorleifson, Erika ^a   Okochi, Eriko ^b   De Boer, Johan G ^a   Ushijima, Toshikazu ^b   Nagao, Minako ^b   Glickman, Barry W ^a  

^a UNIVERSITY OF VICTORIA   (Canada)

^b NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

Author keywords

2 Amino 1 methyl 6 phenylimidazo 4,5 b pyridine; Big Blue ; cII; Colon; lacI; Mutation frequency; Mutational spectrum; PhIP; Transgenic rat

Indexed keywords

2 AMINO 1 METHYL 6 PHENYLIMIDAZO[4,5 B]PYRIDINE; CARCINOGEN; MUTAGENIC AGENT; NUCLEOTIDE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLON; CONTROLLED STUDY; DNA SEQUENCE; FEMALE; GENE MUTATION; MALE; MUTATION RATE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RAT; TRANSGENE; TRANSGENIC ANIMAL;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BACTERIAL PROTEINS; BASE SEQUENCE; CARCINOGENS; COLON; DNA; DNA MUTATIONAL ANALYSIS; ESCHERICHIA COLI PROTEINS; FEMALE; FRAMESHIFT MUTATION; IMIDAZOLES; MALE; MICE; MUTAGENESIS, INSERTIONAL; MUTATION; POINT MUTATION; RATS; RATS, INBRED F344; REPRESSOR PROTEINS; SEQUENCE DELETION; TRANSCRIPTION FACTORS; TRANSGENES; VIRAL PROTEINS;

ANIMALIA; MUS MUSCULUS;

EID: 0034691685     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(00)00058-0     Document Type: Article

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