Mutagenicity of 4-nitroquinoline 1-oxide in the Muta(TM)mouse

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 444, Issue 2, 1999, Pages 321-336

  Nakajima, Madoka ^a   Kikuchi, Masanori ^a   Saeki, Kenichi ^b   Miyata, Yuko ^b   Terada, Megumi ^c   Kishida, Fumio ^d   Yamamoto, Reiko ^d   Furihata, Chie ^e   Dean, Stephen W ^f  

^a Biosafety Research Center   (Japan)

^b NAGOYA CITY UNIVERSITY   (Japan)

^c KUMIAI CHEMICAL INDUSTRY CO LTD   (Japan)

^d SUMITOMO CHEMICAL CO LTD   (Japan)

^e UNIVERSITY OF TOKYO   (Japan)

^f UK   (United Kingdom)

Author keywords

4 Nitroquinoline 1 oxide; lacZ; Transgenic mouse

Indexed keywords

4 NITROQUINOLINE 1 OXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; GENE MUTATION; GENOTOXICITY; MALE; MICRONUCLEUS TEST; MOUSE; MUTAGENICITY; NONHUMAN; PRIORITY JOURNAL; TISSUE SPECIFICITY; TRANSGENIC MOUSE;

4-NITROQUINOLINE-1-OXIDE; ANIMALS; CARCINOGENS; LAC OPERON; MALE; MICE; MICE, TRANSGENIC; MUTAGENS; MUTATION; ORGAN SPECIFICITY; TIME FACTORS;

EID: 0032837167     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1383-5718(99)00105-9     Document Type: Article

References (17)

1. Suzuki T., Itoh S., Nakajima M., Hachiya N., Hara T. Target organ and time-course in the mutagenicity of five carcinogens in MutaMouse; a summary report of the second collaborative study on the transgenic mutation assay by JEMS/MMS. Mutat. Res. (this issue). 444:1999;259-268.
2. McCann J. Detection of carcinogens as mutagens: bacterial tester strains with R factor plasmids. Proc. Natl. Acad. Sci. 72:1975;979-983.
3. Shiraishi Y., Sandberg A.A. Effects of various chemical agents on sister chromatid exchanges, chromosome aberrations, and DNA repair in normal and abnormal human lymphoid cell lines. J. Natl. Cancer Inst. 62:1979;27-35.
4. Wild D. Cytogenetic effect in the mouse of 17 chemical mutagens and carcinogens evaluated by the micronucleus test. Mutat. Res. 56:1978;319-327.
5. Ohne M., Satoh T., Yamada S., Takai H. Experimental tongue carcinoma of rats induced by oral administration of 4-nitroquinoline 1-oxide (4NQO) in drinking water. Oral Surg. 59:1985;600-607.
6. Steidler N.E., Reade P.C. Initiation and promotion of experimental oral mucosal carcinogenesis in mice. J. Oral Pathol. 15:1986;43-47.
7. Crane I.J., Luker J., Stone A., Scully C., Prime S.S. Characterization of malignant rat culture following the induction of oral squamous cell carcinomas in vivo. Carcinogenesis. 7:1986;1723-1727.
8. Kohler S.W., Provost G.S., Kretz P.L., Fieck A., Sorge J.A., Short J.M. The use of transgenic mice for short-term in vivo mutagenicity testing. GATA. 7:1990;212-218.
9. Suzuki T., Itoh T., Hayashi M., Nishikawa S., Ikezaki F., Furukawa M., Shimada H., Sofuni T. Organ variation in the mutagenicity of dimethylnitrosamine in Big Blue mice. Environ. Mol. Mutagen. 28:1996;348-353.
10. Buffone G.J. Isolation of DNA from biological specimens without extraction with phenol. Clin. Chem. 31:1985;164-165.
11. Davis R.W. Rapid DNA isolations for enzymatic and hybridization analysis. Methods Enzymol. 65:1980;404-411.
12. Epicentre Forum, High efficiency transgenic DNA rescue using the MutaPlax™ transgenic lambda DNA packaging system, 2 (1995) 1-3.
13. Gunther E.J., Murray N.E., Glazer P.M. Application of galactose-sensitive E. coli strains as selective hosts for lacZ-plasmids. Nucleic Acids Res. 21:1993;3903-3904.
14. Mutation Assay Manual, Muta™ mouse/PE: Positive Selection System, Covance, VA, 1995.
15. I. Yoshimura, Y. Ohashi, Statistical Analysis for Toxicology Data, Chijin-shokan (1992) 37-39.
16. Hayashi M., Morita T., Kodama Y., Sofuni T., Ishidate M. Jr. The micronucleus assay with mouse peripheral blood reticulocytes using acridine orange-coated slides. Mutat. Res. 245:1990;245-249.
17. Kastenbaum M.A., Bowman K.O. Tables for determining the statistical significance of mutation frequencies. Mutat. Res. 9:1970;527-549.