Transgenic mouse mutation assay systems can play an important role in regulatory mutagenicity testing in vivo for the detection of site-of-contact mutagens

Mutagenesis

Volumn 14, Issue 1, 1999, Pages 141-151

  Dean, S W ^a   Brooks, T M ^a   Burlinson, B ^b   Mirsalis, J ^c   Myhr, B ^a   Recio, L ^d   Thybaud, V ^e  

^a UK   (United States)

^b GLAXOSMITHKLINE   (United Kingdom)

^c SRI INTERNATIONAL   (United States)

^d CIIT CENTERS FOR HEALTH RESEARCH   (United States)

^e SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

1,3 BUTADIENE; 7,12 DIMETHYLBENZ[A]ANTHRACENE; BENZENE; BENZO[A]PYRENE; DIMETHYLNITROSAMINE; DNA; METHYLNITROSOUREA; MUTAGENIC AGENT; NITROQUINOLINE DERIVATIVE; PROPIOLACTONE; PYRENE DERIVATIVE; URETHAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD; BONE MARROW; CYTOGENETICS; EXPOSURE; GENETIC TOXICOLOGY; GENOTOXICITY; INHALATION; LIVER; LUNG; MOUSE; MUTAGEN TESTING; NONHUMAN; PRIORITY JOURNAL; RISK ASSESSMENT; SKIN; STOMACH; TARGET ORGAN; TRANSGENIC MOUSE; UNSCHEDULED DNA SYNTHESIS;

ANIMALS; HUMANS; MICE; MICE, TRANSGENIC; MUTAGENICITY TESTS; MUTAGENS; MUTATION;

ANIMALIA; MUS MUSCULUS;

EID: 0032936730     PISSN: 02678357     EISSN: None     Source Type: Journal    
DOI: 10.1093/mutage/14.1.141     Document Type: Article

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