Mutagenic activity of carcinogens detected in transgenic rodent mutagenicity assays at dose levels used in chronic rodent cancer bioassays

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 405, Issue 2, 1998, Pages 193-198

  Schmezer, Peter ^a   Eckert, Claudia ^a   Liegibel, Ute M ^b   Zelezny, Otto ^a   Klein, Reinhold G ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b FEDERAL RESEARCH INSTITUTE OF NUTRITION AND FOOD   (Germany)

Author keywords

Dose selection; In vivo mutation; lacI; lacZ; Transgenic rodents

Indexed keywords

1,2 DIBROMOETHANE; AFLATOXIN B1; BENZENE; CHLORAMBUCIL; CYCLOPHOSPHAMIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; BIOASSAY; CARCINOGENICITY; CONFERENCE PAPER; CONTROLLED STUDY; INTRAPERITONEAL DRUG ADMINISTRATION; MOUSE; MUTAGENIC ACTIVITY; MUTATION RATE; NONHUMAN; PRIORITY JOURNAL; RAT; TARGET ORGAN; TRANSGENIC ANIMAL; TRANSGENIC MOUSE;

ANIMALS; CARCINOGENICITY TESTS; CARCINOGENS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; LUNG; MICE; MICE, TRANSGENIC; MUTAGENICITY TESTS; NASAL MUCOSA; RATS;

RODENTIA;

EID: 0032552574     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(98)00136-5     Document Type: Conference Paper

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