메뉴 건너뛰기




Volumn 104, Issue SUPPL. 3, 1996, Pages 683-686

Distinction of mutagenic carcinogens from a mutagenic noncarcinogen in the big blue transgenic mouse

Author keywords

Big Blue; Diaminotoluene; Dimethylnitrosamine; in vivo mutation assay; lacl; Mutagenic noncarcinogens; Transgenic mice

Indexed keywords

2,4 DIAMINOTOLUENE; 2,6 DIAMINOTOLUENE; CARCINOGEN; DIMETHYLNITROSAMINE;

EID: 0029991783     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.96104s3683     Document Type: Conference Paper
Times cited : (17)

References (19)
  • 2
    • 0028178048 scopus 로고
    • A preliminary evaluation of the performance of the Muta Mouse (lacZ) and Big Blue (lacI) transgenic mouse mutation assays
    • Morrison V, Ashby J. A preliminary evaluation of the performance of the Muta Mouse (lacZ) and Big Blue (lacI) transgenic mouse mutation assays. Mutagenesis 9:367-375 (1994).
    • (1994) Mutagenesis , vol.9 , pp. 367-375
    • Morrison, V.1    Ashby, J.2
  • 3
    • 0004078420 scopus 로고
    • Bioassay of 2,4-Diaminotoluene for Possible Carcinogenicity
    • Bethesda, MD:U.S. Department of Health, Education and Welfare
    • U. S. Department of Health, Education, and Welfare, Public Health Service, National Institutes of Health. Bioassay of 2,4-Diaminotoluene for Possible Carcinogenicity. NCI Carcinogenesis Technical Report Series 162. Bethesda, MD:U.S. Department of Health, Education and Welfare, 1979.
    • (1979) NCI Carcinogenesis Technical Report Series 162
  • 4
    • 0842307733 scopus 로고
    • Bioassay of 2,6-Toluenediamine Hydrochloride for Possible Carcinogenicity
    • Bethesda, MD:U.S. Department of Health, Education and Welfare
    • U. S. Department of Health, Education, and Welfare, Public Health Service, National Institutes of Health. Bioassay of 2,6-Toluenediamine Hydrochloride for Possible Carcinogenicity. NCI Carcinogenesis Technical Report Series 200. Bethesda, MD:U.S. Department of Health, Education and Welfare, 1980.
    • (1980) NCI Carcinogenesis Technical Report Series 200
  • 5
    • 0023704076 scopus 로고
    • Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals
    • Zeiger E, Anderson B, Haworth S, Lawlor T, Mortlemans K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals. Environ Mol Mutagen 11(Suppl 12):1-157 (1988).
    • (1988) Environ Mol Mutagen , vol.11 , Issue.12 SUPPL. , pp. 1-157
    • Zeiger, E.1    Anderson, B.2    Haworth, S.3    Lawlor, T.4    Mortlemans, K.5
  • 6
    • 0024845303 scopus 로고
    • Metabolism, disposition, and mutagenicity of 2,6-diaminotoluene, a mutagenic noncarcinogen
    • Cunningham ML, Burka LT, Matthews HB. Metabolism, disposition, and mutagenicity of 2,6-diaminotoluene, a mutagenic noncarcinogen. Drug Metab Dispos 17:612-617 (1989).
    • (1989) Drug Metab Dispos , vol.17 , pp. 612-617
    • Cunningham, M.L.1    Burka, L.T.2    Matthews, H.B.3
  • 10
    • 0027311053 scopus 로고
    • Mutations in liver DNA of lacI transgenic mice (Big Blue) following subchronic exposure to 2-acetylaminofluorene
    • Shephard SE, Sengstag C, Lutz WK, Schlatter C. Mutations in liver DNA of lacI transgenic mice (Big Blue) following subchronic exposure to 2-acetylaminofluorene. Mutat Res 302:91-96 (1993).
    • (1993) Mutat Res , vol.302 , pp. 91-96
    • Shephard, S.E.1    Sengstag, C.2    Lutz, W.K.3    Schlatter, C.4
  • 11
    • 0028786875 scopus 로고
    • Analysis of in vivo mutation frequency in liver DNA of lacI transgenic mice following subchronic exposure to the carcinogen-noncarcinogen pair 2,4- and 2,6-diaminotoluene
    • Hayward JJ, Shane BS, Tindall KR, Cunningham ML. Analysis of in vivo mutation frequency in liver DNA of lacI transgenic mice following subchronic exposure to the carcinogen-noncarcinogen pair 2,4- and 2,6-diaminotoluene. Carcinogenesis, 16:2429-2433 (1995).
    • (1995) Carcinogenesis , vol.16 , pp. 2429-2433
    • Hayward, J.J.1    Shane, B.S.2    Tindall, K.R.3    Cunningham, M.L.4
  • 13
    • 0028335008 scopus 로고
    • Mutation studies with dimethyl nitrosamine in young and old lacI transgenic mice
    • Tinwell H, Lefevre PA, Ashby J. Mutation studies with dimethyl nitrosamine in young and old lacI transgenic mice. Mutat Res 307:501-508 (1994).
    • (1994) Mutat Res , vol.307 , pp. 501-508
    • Tinwell, H.1    Lefevre, P.A.2    Ashby, J.3
  • 15
    • 0344695138 scopus 로고
    • Effect of partial hepatectomy on the mutant frequency of benzo(a)pyrene in the liver of C57B1/6 transgenic mice
    • Shane BS, Tindall KR. Effect of partial hepatectomy on the mutant frequency of benzo(a)pyrene in the liver of C57B1/6 transgenic mice [Abstract]. Environ Mol Mutagen 23(Suppl 23):61 (1994).
    • (1994) Environ Mol Mutagen , vol.23 , Issue.23 SUPPL. , pp. 61
    • Shane, B.S.1    Tindall, K.R.2
  • 16
    • 0020397479 scopus 로고
    • Detection of genotoxic carcinogens in the in vivo-in vitro hepatocyte DNA repair assay
    • Mirsalis JC, Tyson CK, Butterworrh BE. Detection of genotoxic carcinogens in the in vivo-in vitro hepatocyte DNA repair assay. Environ Mutagen 4:553-562 (1982).
    • (1982) Environ Mutagen , vol.4 , pp. 553-562
    • Mirsalis, J.C.1    Tyson, C.K.2    Butterworrh, B.E.3
  • 17
    • 0026073504 scopus 로고
    • Correlation of hepatocellular proliferation with hepatocarcinogenicity induced by the mutagenic noncarcinogen: Carcinogen pair- 2,6- and 2,4-diaminotoluene
    • Cunningham ML, Foley J, Maronpot RR, Matthews HB. Correlation of hepatocellular proliferation with hepatocarcinogenicity induced by the mutagenic noncarcinogen: carcinogen pair- 2,6- and 2,4-diaminotoluene. Toxicol Appl Pharmacol 107:562-567 (1991).
    • (1991) Toxicol Appl Pharmacol , vol.107 , pp. 562-567
    • Cunningham, M.L.1    Foley, J.2    Maronpot, R.R.3    Matthews, H.B.4
  • 18
    • 0017840941 scopus 로고
    • Influence of repeated liver regeneration on hepatic carcinogenesis by diethylnitrosamine in mice
    • Pound AW, McGuire LJ. Influence of repeated liver regeneration on hepatic carcinogenesis by diethylnitrosamine in mice. Br J Cancer 37:595-602 (1978).
    • (1978) Br J Cancer , vol.37 , pp. 595-602
    • Pound, A.W.1    McGuire, L.J.2
  • 19
    • 0028169360 scopus 로고
    • 6-methylguanine-DNA adducts protects transgenic mice from N-methylnitrosourea-induced thymic lymphomas
    • 6-methylguanine-DNA adducts protects transgenic mice from N-methylnitrosourea-induced thymic lymphomas. Cancer Res 54:4648-4652 (1994).
    • (1994) Cancer Res , vol.54 , pp. 4648-4652
    • Liu, L.1    Allay, E.2    Dumenco, L.L.3    Gerson, S.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.