-
2
-
-
1642323484
-
Pyrrolizidine alkaloids-genotoxicity, metabolism enzymes, metabolic activation, and mechanisms
-
Fu, P. P., Xia, Q., Lin, G., and Chou, M. W. (2004) Pyrrolizidine alkaloids-genotoxicity, metabolism enzymes, metabolic activation, and mechanisms. Drug Metab. Rev. 36, 1-55.
-
(2004)
Drug Metab. Rev.
, vol.36
, pp. 1-55
-
-
Fu, P.P.1
Xia, Q.2
Lin, G.3
Chou, M.W.4
-
3
-
-
0041563672
-
Toxicology and carcinogenesis studies of riddelliine (CAS No. 23246-96-0) in F344/N rats and B6C3F1 mice (gavage studies)
-
National Toxicology Program (2003) Toxicology and carcinogenesis studies of riddelliine (CAS No. 23246-96-0) in F344/N rats and B6C3F1 mice (gavage studies). Natl. Toxicol. Program Technol. Rep. Ser. 508, 1-280.
-
(2003)
Natl. Toxicol. Program Technol. Rep. Ser.
, vol.508
, pp. 1-280
-
-
-
4
-
-
0041632143
-
Toxicology and carcinogenicity of riddelliine in rats and mice
-
Chan, P. C., Haseman, J. K., Prejean, J. D., and Nyska, A. (2003) Toxicology and carcinogenicity of riddelliine in rats and mice. Toxicol. Lett. 144, 295-311.
-
(2003)
Toxicol. Lett.
, vol.144
, pp. 295-311
-
-
Chan, P.C.1
Haseman, J.K.2
Prejean, J.D.3
Nyska, A.4
-
5
-
-
0027981421
-
Toxicity and carcinogenicity of riddelliine following 13 weeks of treatment to rats and mice
-
Chan, P. C., Mahler, J., Bucher, J. R., Travlos, G. S., and Reid, J. B. (1994) Toxicity and carcinogenicity of riddelliine following 13 weeks of treatment to rats and mice. Toxicon 32, 891-908.
-
(1994)
Toxicon
, vol.32
, pp. 891-908
-
-
Chan, P.C.1
Mahler, J.2
Bucher, J.R.3
Travlos, G.S.4
Reid, J.B.5
-
6
-
-
0036354635
-
Toxicokineties of riddelliine, a carcinogenic pyrrolizidine alkaloid, and metabolites in rats and mice
-
Williams, L., Chou, M. W., Yan, J., Young, J. F., Chan, P. C., and Doerge, D. R. (2002) Toxicokineties of riddelliine, a carcinogenic pyrrolizidine alkaloid, and metabolites in rats and mice. Toxicol. Appl. Pharmacol. 182, 98-104.
-
(2002)
Toxicol. Appl. Pharmacol.
, vol.182
, pp. 98-104
-
-
Williams, L.1
Chou, M.W.2
Yan, J.3
Young, J.F.4
Chan, P.C.5
Doerge, D.R.6
-
7
-
-
0037253576
-
Human liver microsomal metabolism and DNA adduct formation of the tumorigenic pyrrolizidine alkaloid, riddelliine
-
Xia, Q., Chou, M. W., Kadlubar, F. F., Chan, P. C., and Fu, P. P. (2003) Human liver microsomal metabolism and DNA adduct formation of the tumorigenic pyrrolizidine alkaloid, riddelliine. Chem. Res. Toxicol. 16, 66-73.
-
(2003)
Chem. Res. Toxicol.
, vol.16
, pp. 66-73
-
-
Xia, Q.1
Chou, M.W.2
Kadlubar, F.F.3
Chan, P.C.4
Fu, P.P.5
-
8
-
-
0035148592
-
Metabolic activation of the tumorigenic pyrrolizidine alkaloid, riddelliine, leading to DNA adduct formation in vivo
-
Yang, Y. C., Yan, J., Doerge, D. R., Chan, P. C., Fu, P. P., and Chou, M. W. (2001) Metabolic activation of the tumorigenic pyrrolizidine alkaloid, riddelliine, leading to DNA adduct formation in vivo. Chem. Res. Toxicol. 14, 101-109.
-
(2001)
Chem. Res. Toxicol.
, vol.14
, pp. 101-109
-
-
Yang, Y.C.1
Yan, J.2
Doerge, D.R.3
Chan, P.C.4
Fu, P.P.5
Chou, M.W.6
-
9
-
-
0141625018
-
Identification of DNA adducts derived from riddelliine, a carcinogenic pyrrolizidine alkaloid
-
Chou, M. W., Yan, J., Williams, L. D., Xia, Q., Churchwell, M., Doerge, D. R., and Fu, P. P. (2003) Identification of DNA adducts derived from riddelliine, a carcinogenic pyrrolizidine alkaloid. Chem. Res. Toxicol. 16, 1130-1137.
-
(2003)
Chem. Res. Toxicol.
, vol.16
, pp. 1130-1137
-
-
Chou, M.W.1
Yan, J.2
Williams, L.D.3
Xia, Q.4
Churchwell, M.5
Doerge, D.R.6
Fu, P.P.7
-
10
-
-
0034693862
-
Recent advances in the protocols of transgenic mouse mutation assays
-
Nohmi, T., Suzuki, T., and Masumura, K. (2000) Recent advances in the protocols of transgenic mouse mutation assays. Mutat. Res. 455, 191-215.
-
(2000)
Mutat. Res.
, vol.455
, pp. 191-215
-
-
Nohmi, T.1
Suzuki, T.2
Masumura, K.3
-
11
-
-
0036798839
-
Mutations induced by alpha-hydroxytamoxifen in the lacI and cII genes of Big Blue transgenic rats
-
Chen, T., Gamboa da Costa, G., Marques, M. M., Shelton, S. D., Beland, F. A., and Manjanatha, M. G. (2002) Mutations induced by alpha-hydroxytamoxifen in the lacI and cII genes of Big Blue transgenic rats. Carcinogenesis 23, 1751-1757.
-
(2002)
Carcinogenesis
, vol.23
, pp. 1751-1757
-
-
Chen, T.1
Gamboa Da Costa, G.2
Marques, M.M.3
Shelton, S.D.4
Beland, F.A.5
Manjanatha, M.G.6
-
12
-
-
0027974704
-
Software for the analysis of mutations at the human hprt gene
-
Cariello, N. F. (1994) Software for the analysis of mutations at the human hprt gene. Mutat. Res. 312, 173-185.
-
(1994)
Mutat. Res.
, vol.312
, pp. 173-185
-
-
Cariello, N.F.1
-
13
-
-
0023264512
-
Statistical test for the comparison of samples from mutational spectra
-
Adams, W. T., and Skopek, T. R. (1987) Statistical test for the comparison of samples from mutational spectra. J. Mol. Biol. 194, 391-396.
-
(1987)
J. Mol. Biol.
, vol.194
, pp. 391-396
-
-
Adams, W.T.1
Skopek, T.R.2
-
14
-
-
0141685700
-
Detection of riddelliine-derived DNA adducts in blood of rats fed riddelliine
-
Yan, J., Nichols, J., Yang, Y. C., Fu, P. P., and Chou, M. W. (2002) Detection of riddelliine-derived DNA adducts in blood of rats fed riddelliine. Int. J. Mol. Sci. 3, 1019-1026.
-
(2002)
Int. J. Mol. Sci.
, vol.3
, pp. 1019-1026
-
-
Yan, J.1
Nichols, J.2
Yang, Y.C.3
Fu, P.P.4
Chou, M.W.5
-
15
-
-
0037466375
-
Correlation of DNA adduct formation and riddelliine-induced liver tumorigenesis in F344 rats and B6C3F1 mice
-
Chou, M. W., Yan, J., Nichols, J., Xia, Q., Beland, F. A., Chan, P. C., and Fu, P. P. (2003) Correlation of DNA adduct formation and riddelliine-induced liver tumorigenesis in F344 rats and B6C3F1 mice. Cancer Lett. 193, 119-125.
-
(2003)
Cancer Lett.
, vol.193
, pp. 119-125
-
-
Chou, M.W.1
Yan, J.2
Nichols, J.3
Xia, Q.4
Beland, F.A.5
Chan, P.C.6
Fu, P.P.7
-
16
-
-
0041732422
-
Chemical-specific alterations in ras, p53, and β-catenin genes in hemangiosarcomas from B6C3F1 mice exposed to o-nitrotoluene or riddelliine for 2 years
-
Hong, H. L., Ton, T. V., Devereux, T. R., Moomaw, C., Clayton, N., Chan, P., Dunnick, J. K., and Sills, R. C. (2003) Chemical-specific alterations in ras, p53, and β-catenin genes in hemangiosarcomas from B6C3F1 mice exposed to o-nitrotoluene or riddelliine for 2 years. Toxicol. Appl. Pharmacol. 191, 227-234.
-
(2003)
Toxicol. Appl. Pharmacol.
, vol.191
, pp. 227-234
-
-
Hong, H.L.1
Ton, T.V.2
Devereux, T.R.3
Moomaw, C.4
Clayton, N.5
Chan, P.6
Dunnick, J.K.7
Sills, R.C.8
-
17
-
-
0035945709
-
Lung-specific mutagenicity and mutational spectrum in B6C3F1 lacI transgenic mice following inhalation exposure to 1,2-epoxybutene
-
Saranko, C. J., Meyer, K. G., Pluta, L. J., Henderson, R. F., and Recio, L. (2001) Lung-specific mutagenicity and mutational spectrum in B6C3F1 lacI transgenic mice following inhalation exposure to 1,2-epoxybutene. Mutat. Res. 473, 37-49.
-
(2001)
Mutat. Res.
, vol.473
, pp. 37-49
-
-
Saranko, C.J.1
Meyer, K.G.2
Pluta, L.J.3
Henderson, R.F.4
Recio, L.5
-
18
-
-
0032053215
-
Specific tandem GG to TT base substitutions induced by acetaldehyde are due to intra-strand cross-links between adjacent guanine bases
-
Matsuda, T., Kawanishi, M., Yagi, T., Matsui, S., and Takebe, H. (1998) Specific tandem GG to TT base substitutions induced by acetaldehyde are due to intra-strand cross-links between adjacent guanine bases. Nucleic Acids Res. 26, 1769-1774.
-
(1998)
Nucleic Acids Res.
, vol.26
, pp. 1769-1774
-
-
Matsuda, T.1
Kawanishi, M.2
Yagi, T.3
Matsui, S.4
Takebe, H.5
-
19
-
-
0025939012
-
Spectrum of cis-diamminedichloroplatinum(II)-induced mutations in a shuttle vector propagated in human cells
-
Bubley, G. J., Ashburner, B. P., and Teicher, B. A. (1991) Spectrum of cis-diamminedichloroplatinum(II)-induced mutations in a shuttle vector propagated in human cells. Mol. Carcinog. 4, 397-406.
-
(1991)
Mol. Carcinog.
, vol.4
, pp. 397-406
-
-
Bubley, G.J.1
Ashburner, B.P.2
Teicher, B.A.3
-
20
-
-
0034694957
-
Mutagenicity in lung of Big Blue mice and induction of tandembase substitutions in Salmonella by the air pollutant peroxyacetyl nitrate (PAN): Predicted formation of intrastrand cross-links
-
DeMarini, D. M., Shelton, M. L., Kohan, M. J., Hudgens, E. E., Kleindienst, T. E., Ball, L. M., Walsh, D., de Boer, J. G., Lewis-Bevan, L., Rabinowitz, J. R., Claxton, L. D., and Lewtas, J. (2000) Mutagenicity in lung of Big Blue mice and induction of tandembase substitutions in Salmonella by the air pollutant peroxyacetyl nitrate (PAN): predicted formation of intrastrand cross-links. Mutat. Res. 457, 41-55.
-
(2000)
Mutat. Res.
, vol.457
, pp. 41-55
-
-
DeMarini, D.M.1
Shelton, M.L.2
Kohan, M.J.3
Hudgens, E.E.4
Kleindienst, T.E.5
Ball, L.M.6
Walsh, D.7
De Boer, J.G.8
Lewis-Bevan, L.9
Rabinowitz, J.R.10
Claxton, L.D.11
Lewtas, J.12
|