A comparative study of in vivo mutation assays: Analysis of hprt, lacI, and cII/cI as mutational targets for N-nitroso-N-methylurea and benzo[a]pyrene in Big Blue(TM) mice

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 421, Issue 1, 1998, Pages 121-136

  Monroe, J J ^a   Kort, K L ^a   Miller, J E ^a   Marino, D R ^a   Skopek, T R ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Benzo a pyrene; Big Blue; cII; hflAB; hprt; lacI; MNU

Indexed keywords

BENZO[A]PYRENE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; METHYLNITROSOUREA;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DNA SEQUENCE; GENE LOCUS; GENE MUTATION; INTERMETHOD COMPARISON; MOUSE; MOUSE STRAIN; MUTATION RATE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; TRANSGENE;

ANIMALS; BACTERIAL PROTEINS; BACTERIOPHAGE LAMBDA; BENZO(A)PYRENE; DNA MUTATIONAL ANALYSIS; DNA-BINDING PROTEINS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; METHYLNITROSOUREA; MICE; MICE, TRANSGENIC; MUTAGENICITY TESTS; MUTAGENS; MUTATION; REPRESSOR PROTEINS; SENSITIVITY AND SPECIFICITY; SPLEEN; T-LYMPHOCYTES; TRANSCRIPTION FACTORS; TRANSGENES; VIRAL PROTEINS;

ANIMALIA;

EID: 0032511836     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(98)00171-7     Document Type: Article

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