메뉴 건너뛰기




Volumn 35, Issue 3, 2000, Pages 253-259

In vivo transgenic mutation assays

(14)  Heddle, John A a   Dean, Stephen b   Nohmi, Takehiko c   Boerrigter, Michaël d   Casciano, Daniel e   Douglas, George R f   Glickman, Barry W g   Gorelick, Nancy J h   Mirsalis, Jon C i   Martus, Hans Jörg j   Skopek, Thomas R k   Thybaud, Veronique l   Tindall, Kenneth R m   Yajima, Nobuhiro n  


Author keywords

BigBlue mouse rat; lacl; lacZ; Muta(TM) Mouse; Transgenic mutation assays

Indexed keywords

ANIMAL CELL; COLONY FORMING UNIT; CONFERENCE PAPER; CONTROLLED STUDY; DIAGNOSTIC VALUE; DNA DETERMINATION; GENE LOCUS; GENE MUTATION; MAXIMUM PERMISSIBLE DOSE; MOUSE; NONHUMAN; RAT; RELIABILITY; TRANSGENIC ANIMAL;

EID: 0034033214     PISSN: 08936692     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2280(2000)35:3<253::AID-EM11>3.0.CO;2-J     Document Type: Conference Paper
Times cited : (109)

References (48)
  • 2
    • 0025765309 scopus 로고
    • Induction of 6-thioguanine-resistant lymphocytes in Fischer 344 rats following in vivo exposure to N-ethyl-N-nitrosourea and cyclophosphamide
    • Aidoo A, Lyn-Cook L, Mittelstaedt R A, Heflich R H and Casciano D A. 1991. Induction of 6-thioguanine-resistant lymphocytes in Fischer 344 rats following in vivo exposure to N-ethyl-N-nitrosourea and cyclophosphamide. Environ Mol Mutagen 17:141-151.
    • (1991) Environ Mol Mutagen , vol.17 , pp. 141-151
    • Aidoo, A.1    Lyn-Cook, L.2    Mittelstaedt, R.A.3    Heflich, R.H.4    Casciano, D.A.5
  • 3
    • 0032749588 scopus 로고    scopus 로고
    • Treatment of LacZ plasmid-based transgenic mice with benzo[a]pyrene: Measurement of DNA adduct levels, mutant frequencies and mutant spectra
    • Boerrigter METI. 2000. Treatment of LacZ plasmid-based transgenic mice with benzo[a]pyrene: measurement of DNA adduct levels, mutant frequencies and mutant spectra. Environ Mol Mutagen 34:140-147.
    • (2000) Environ Mol Mutagen , vol.34 , pp. 140-147
    • Boerrigter, M.E.T.I.1
  • 4
    • 0031005090 scopus 로고    scopus 로고
    • Sources of variability in mutant frequency determinations in different organs of lacZ plasmid-based transgenic mice: Experimental features and statistical analysis
    • Boerrigter METI, Vijg J. 1997. Sources of variability in mutant frequency determinations in different organs of lacZ plasmid-based transgenic mice: experimental features and statistical analysis. Environ Mol Mutagen 29:221-229.
    • (1997) Environ Mol Mutagen , vol.29 , pp. 221-229
    • Boerrigter, M.E.T.I.1    Vijg, J.2
  • 6
    • 0032725344 scopus 로고    scopus 로고
    • Kinetics of induction of DNA damage and LacZ gene mutations in stomach mucosa of mice treated with β-propiolactone and N-methyl-N'-nitro-N-nitrosoguanidine, using single-cell gel electrophoresis and Muta™-Mouse models
    • Brault D, Renault D, Tombolan F, Thybaud V. 2000. Kinetics of induction of DNA damage and LacZ gene mutations in stomach mucosa of mice treated with β-propiolactone and N-methyl-N'-nitro-N-nitrosoguanidine, using single-cell gel electrophoresis and Muta™-Mouse models. Environ Mol Mutagen 34:182-189.
    • (2000) Environ Mol Mutagen , vol.34 , pp. 182-189
    • Brault, D.1    Renault, D.2    Tombolan, F.3    Thybaud, V.4
  • 7
    • 0011980193 scopus 로고
    • The *X174 bacteriophage shuttle vector for the study of mutagenesis
    • Burkhart JG, Winn RN, VanBeneden R, Malling HV. 1992. The *X174 bacteriophage shuttle vector for the study of mutagenesis. Environ Mol Mutagen 19(Suppl 20):8.
    • (1992) Environ Mol Mutagen , vol.19 , Issue.SUPPL. 20 , pp. 8
    • Burkhart, J.G.1    Winn, R.N.2    VanBeneden, R.3    Malling, H.V.4
  • 9
    • 0029038488 scopus 로고
    • Statistical design and analysis of mutation studies in transgenic mice
    • Carr GJ, Gorelick NJ. 1995. Statistical design and analysis of mutation studies in transgenic mice. Environ Mol Mutagen 25:246-255.
    • (1995) Environ Mol Mutagen , vol.25 , pp. 246-255
    • Carr, G.J.1    Gorelick, N.J.2
  • 10
    • 0030329707 scopus 로고    scopus 로고
    • A test for neutrality of mutations of the lacZ transgene
    • Cosentino L, Heddle J A. 1996. A test for neutrality of mutations of the lacZ transgene. Environ Mol Mutagen 28:313-316.
    • (1996) Environ Mol Mutagen , vol.28 , pp. 313-316
    • Cosentino, L.1    Heddle, J.A.2
  • 11
    • 0032965173 scopus 로고    scopus 로고
    • A comparison of the effects of diverse mutagens at the lacZ and Dlb-I loci in vivo
    • Cosentino L, Heddle J A. 1999. A comparison of the effects of diverse mutagens at the lacZ and Dlb-I loci in vivo. Mutagenesis 14:113-119.
    • (1999) Mutagenesis , vol.14 , pp. 113-119
    • Cosentino, L.1    Heddle, J.A.2
  • 12
    • 0032936730 scopus 로고    scopus 로고
    • Transgenic mouse mutation assay systems can play an important role in regulatory testing in vivo for the detection of site-of-contact mutagens
    • Dean SW, Brooks TM, Burlinson B, Mirsalis J, Myhr B, Recio L, Thybaud V. 1999. Transgenic mouse mutation assay systems can play an important role in regulatory testing in vivo for the detection of site-of-contact mutagens. Mutagenesis 14:141-145.
    • (1999) Mutagenesis , vol.14 , pp. 141-145
    • Dean, S.W.1    Brooks, T.M.2    Burlinson, B.3    Mirsalis, J.4    Myhr, B.5    Recio, L.6    Thybaud, V.7
  • 15
    • 0032942963 scopus 로고    scopus 로고
    • Characterization of color mutants in lacZ plasmid-based transgenic mice, as detected by positive selection
    • Dollé MET, Martus H-J, Novak M, van Orsouw NJ, Vijg J. 1999. Characterization of color mutants in lacZ plasmid-based transgenic mice, as detected by positive selection. Mutagenesis 14:287-293.
    • (1999) Mutagenesis , vol.14 , pp. 287-293
    • Dollé, M.E.T.1    Martus, H.-J.2    Novak, M.3    Van Orsouw, N.J.4    Vijg, J.5
  • 16
    • 0030337742 scopus 로고    scopus 로고
    • Temporal and molecular characteristics of lacZ mutations in somatic tissues of transgenic mice
    • Douglas G, Jiao J, Gingerich JR, Soper LM, Gossen JA. 1996. Temporal and molecular characteristics of lacZ mutations in somatic tissues of transgenic mice. Environ Mol Mutagen 28:317-324.
    • (1996) Environ Mol Mutagen , vol.28 , pp. 317-324
    • Douglas, G.1    Jiao, J.2    Gingerich, J.R.3    Soper, L.M.4    Gossen, J.A.5
  • 17
    • 0029061266 scopus 로고
    • Overview of mutation assays in transgenic mice for routine testing
    • Gorelick NJ. 1995. Overview of mutation assays in transgenic mice for routine testing. Environ Mol Mutagen 25:218-230.
    • (1995) Environ Mol Mutagen , vol.25 , pp. 218-230
    • Gorelick, N.J.1
  • 19
    • 0029098657 scopus 로고
    • Spontaneous and X-ray-induce deletion mutations in a lacZ plasmid-based transgenic mouse model
    • Gossen JA, Martus H-J, Wei JY, Vijg J. 1995. Spontaneous and X-ray-induce deletion mutations in a lacZ plasmid-based transgenic mouse model. Mutat Res 331:89-97.
    • (1995) Mutat Res , vol.331 , pp. 89-97
    • Gossen, J.A.1    Martus, H.-J.2    Wei, J.Y.3    Vijg, J.4
  • 21
    • 0021857850 scopus 로고
    • A method to quantify spontaneous and in vivo induced thioguanine-resistant mouse lymphocytes
    • Jones IM, Burkhart-Shultz K, Carrano AV. 1985. A method to quantify spontaneous and in vivo induced thioguanine-resistant mouse lymphocytes. Mutat Res 147:97-105.
    • (1985) Mutat Res , vol.147 , pp. 97-105
    • Jones, I.M.1    Burkhart-Shultz, K.2    Carrano, A.V.3
  • 23
    • 0032486138 scopus 로고    scopus 로고
    • Comparison of in vivo mutagenesis in the endogenous Hprt gene and the lacI transgene in Big Blue™ rats treated with 7,12-dimethylbenz[a]anthracene (DMBA)
    • Manjanatha MG, Shelton SD, Aidoo A, Lyn-Cook LE, Casciano DA. 1998. Comparison of in vivo mutagenesis in the endogenous Hprt gene and the lacI transgene in Big Blue™ rats treated with 7,12-dimethylbenz[a]anthracene (DMBA). Mutat Res 401:165-178.
    • (1998) Mutat Res , vol.401 , pp. 165-178
    • Manjanatha, M.G.1    Shelton, S.D.2    Aidoo, A.3    Lyn-Cook, L.E.4    Casciano, D.A.5
  • 26
    • 0029556957 scopus 로고
    • Transgenic models for detection of mutations in tumors and normal tissues of rodents
    • Mirsalis JC. 1995. Transgenic models for detection of mutations in tumors and normal tissues of rodents. Toxicol Lett 82:131-134.
    • (1995) Toxicol Lett , vol.82 , pp. 131-134
    • Mirsalis, J.C.1
  • 27
    • 0028178048 scopus 로고
    • A preliminary evaluation of the performance of the Muta™Mouse (lacZ) and Big Blue™ (lacI) transgenic mouse mutation assays
    • Morrison V, Ashby J. 1994. A preliminary evaluation of the performance of the Muta™Mouse (lacZ) and Big Blue™ (lacI) transgenic mouse mutation assays. Mutagenesis 4:367-375.
    • (1994) Mutagenesis , vol.4 , pp. 367-375
    • Morrison, V.1    Ashby, J.2
  • 31
    • 0030721962 scopus 로고    scopus 로고
    • On the origin of spontaneous somatic mutations and sectored plaques detected in transgenic mice
    • Paashuis-Lew Y, Zhang XB, Heddle JA. 1997. On the origin of spontaneous somatic mutations and sectored plaques detected in transgenic mice. Mutat Res 373:277-284.
    • (1997) Mutat Res , vol.373 , pp. 277-284
    • Paashuis-Lew, Y.1    Zhang, X.B.2    Heddle, J.A.3
  • 34
    • 0028991066 scopus 로고
    • Mutation of the endogenous hprt gene and lacI transgene in ENU-treated Big Blue™ B6C3F1 mice
    • Skopek TR, Kort KL, Marino DR. 1995. Mutation of the endogenous hprt gene and lacI transgene in ENU-treated Big Blue™ B6C3F1 mice. Environ Mol Mutagen 26:9-15.
    • (1995) Environ Mol Mutagen , vol.26 , pp. 9-15
    • Skopek, T.R.1    Kort, K.L.2    Marino, D.R.3
  • 38
    • 0027421332 scopus 로고
    • Comparison of somatic mutation in a transgenic versus host locus
    • Tao KS, Urlando C, Heddle JA. 1993a. Comparison of somatic mutation in a transgenic versus host locus. Proc Nail Acad Sci USA 90:10681-10685.
    • (1993) Proc Nail Acad Sci U S A , vol.90 , pp. 10681-10685
    • Tao, K.S.1    Urlando, C.2    Heddle, J.A.3
  • 39
    • 0027521327 scopus 로고
    • Mutagenicity of methyl methane-sulphonate (MMS) in vivo in the Dlb-I native locus and the LacI transgene
    • Tao KS, Urlando C, Heddle JA. 1993b. Mutagenicity of methyl methane-sulphonate (MMS) in vivo in the Dlb-I native locus and the LacI transgene. Environ Mol Mutagen 22:293-296.
    • (1993) Environ Mol Mutagen , vol.22 , pp. 293-296
    • Tao, K.S.1    Urlando, C.2    Heddle, J.A.3
  • 40
    • 0028177266 scopus 로고
    • The accumulation and persistence of somatic mutations
    • Tao KS, Heddle JA. 1994. The accumulation and persistence of somatic mutations. Mutagenesis 9:187-191.
    • (1994) Mutagenesis , vol.9 , pp. 187-191
    • Tao, K.S.1    Heddle, J.A.2
  • 41
    • 0032921794 scopus 로고    scopus 로고
    • Kinetics of induction of DNA adducts, cell proliferation and gene mutations in the liver of Muta™Mice treated with 5,9-dimethyl-dibenzo[c,g]carbazole
    • Tombolan F, Renault D, Brault D, Guffroy M, Périn-Roussel O, Périn F, Thybaud T. 1999a. Kinetics of induction of DNA adducts, cell proliferation and gene mutations in the liver of Muta™Mice treated with 5,9-dimethyl-dibenzo[c,g]carbazole. Carcinogenesis 20:125-132.
    • (1999) Carcinogenesis , vol.20 , pp. 125-132
    • Tombolan, F.1    Renault, D.2    Brault, D.3    Guffroy, M.4    Périn-Roussel, O.5    Périn, F.6    Thybaud, T.7
  • 42
    • 0032808216 scopus 로고    scopus 로고
    • Effect of mitogenic or regenerative cell proliferation on lacZ mutant frequency in the liver of Muta™Mice treated with 5,9-dimethyl-dibenzo[c,g]carbazole
    • Tombolan F, Renault D, Brault D, Guffroy M, Périn F, Thybaud T. 1999b. Effect of mitogenic or regenerative cell proliferation on lacZ mutant frequency in the liver of Muta™Mice treated with 5,9-dimethyl-dibenzo[c,g]carbazole. Carcinogenesis 20:1357-1362.
    • (1999) Carcinogenesis , vol.20 , pp. 1357-1362
    • Tombolan, F.1    Renault, D.2    Brault, D.3    Guffroy, M.4    Périn, F.5    Thybaud, T.6
  • 43
    • 0003072803 scopus 로고    scopus 로고
    • Bacteriophage lambda and plasmid lacZ transgenic mice for studying mutations in vivo
    • Pfeifer GP, editor. New York: Plenum Press
    • Vijg J, Douglas GR. 1996. Bacteriophage lambda and plasmid lacZ transgenic mice for studying mutations in vivo. In: Pfeifer GP, editor. Technologies for detection of DNA damage and mutation. New York: Plenum Press, p 391-410.
    • (1996) Technologies for Detection of DNA Damage and Mutation , pp. 391-410
    • Vijg, J.1    Douglas, G.R.2
  • 44
    • 0029821901 scopus 로고    scopus 로고
    • Frequency and spectrum of ethylnitrosourea-induced mutation at the hprt and lacI loci in splenic lymphocytes of exposed lacI transgenic mice
    • Walker VE, Gorelick NJ, Andrews JL, Craft TR, deBoer JG, Glickman BW, Skopek TR. 1996. Frequency and spectrum of ethylnitrosourea-induced mutation at the hprt and lacI loci in splenic lymphocytes of exposed lacI transgenic mice. Cancer Res 56:4654-4661.
    • (1996) Cancer Res , vol.56 , pp. 4654-4661
    • Walker, V.E.1    Gorelick, N.J.2    Andrews, J.L.3    Craft, T.R.4    DeBoer, J.G.5    Glickman, B.W.6    Skopek, T.R.7
  • 46
    • 0023894101 scopus 로고
    • A clonal marker induced by mutation in mouse intestinal epithelium
    • Winton DJ, Blount MA, Ponder BAJ. 1988. A clonal marker induced by mutation in mouse intestinal epithelium. Nature 333:463-466.
    • (1988) Nature , vol.333 , pp. 463-466
    • Winton, D.J.1    Blount, M.A.2    Ponder, B.A.J.3
  • 47
    • 0029133857 scopus 로고
    • Factors affecting somatic mutation frequencies in vivo
    • Zhang XB, Urlando C, Tao KS, Heddle J A. 1995. Factors affecting somatic mutation frequencies in vivo. Mutat Res 338:189-201.
    • (1995) Mutat Res , vol.338 , pp. 189-201
    • Zhang, X.B.1    Urlando, C.2    Tao, K.S.3    Heddle, J.A.4
  • 48
    • 0343762013 scopus 로고    scopus 로고
    • Intestinal mutagenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and amino(α)carboline (AαC) in transgenic mice
    • Zhang XB, Felton J, Tucker JD, Urlando C, Heddle JA. 1996. Intestinal mutagenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and amino(α)carboline (AαC) in transgenic mice. Carcinogenesis 17:2259-2265.
    • (1996) Carcinogenesis , vol.17 , pp. 2259-2265
    • Zhang, X.B.1    Felton, J.2    Tucker, J.D.3    Urlando, C.4    Heddle, J.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.