Novel transgenic rat for in vivo genotoxicity assays using 6-thioguanine and Spi- selection

Environmental and Molecular Mutagenesis

Volumn 41, Issue 4, 2003, Pages 253-259

  Hayashi, Hiroyuki ^a,c   Kondo, Hiroshi ^a   Masumura, Ken ichi ^b   Shindo, Yasuhiro ^a   Nohmi, Takehiko ^b  

^a YRP Mobile Telecommunications Key   (Japan)

^b NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^c MEIJI SEIKA KAISHA LTD   (Japan)

Author keywords

6 Thioguanine selection; Deletion mutation; Gpt delta rat; Spi selection

Indexed keywords

BENZO[A]PYRENE; ETHYLNITROSOUREA; TIOGUANINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIOPHAGE; CONTROLLED STUDY; DOSE RESPONSE; ESCHERICHIA COLI; GAM GENE; GENE; GENE DELETION; GENOTOXICITY; GPT GENE; IN VIVO STUDY; KINETICS; MOUSE; MUTAGENICITY; NONHUMAN; POINT MUTATION; RAT; RED GENE; SPECIES DIFFERENTIATION; TRANSGENIC ANIMAL; TRANSGENIC MOUSE;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CHROMOSOME MAPPING; ETHYLNITROSOUREA; MUTAGENICITY TESTS; MUTAGENS; RATS; RATS, SPRAGUE-DAWLEY; SELECTION (GENETICS); THIOGUANINE;

MUS MUSCULUS; RODENTIA;

EID: 0038408908     PISSN: 08936692     EISSN: None     Source Type: Journal    
DOI: 10.1002/em.10152     Document Type: Article

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