Assessment of the in vivo mutagenicity of ethylene oxide in the tissues of B6C3F1 lacI transgenic mice following inhalation exposure

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 391, Issue 3, 1997, Pages 153-164

  Sisk, Susan C ^a,b   Pluta, Linda J ^a   Meyer, Kathy G ^a   Wong, Brian C ^a   Recio, Leslie ^a  

^a CIIT CENTERS FOR HEALTH RESEARCH   (United States)

^b ClinTrials Research   (United States)

Author keywords

Ethylene oxide; In vivo mutation; Inhalation exposure; LacI; Mutant frequency; Mutation spectrum

Indexed keywords

ETHYLENE OXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOASSAY; BONE MARROW; CONTROLLED STUDY; DNA SEQUENCE; DOSE RESPONSE; GENE DELETION; GERM CELL; INHALATION; LETHAL MUTANT; LUNG; MALE; MOUSE; MUTAGENICITY; MUTATION RATE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; SPLEEN; TISSUE LEVEL; TRANSGENE; TRANSGENIC MOUSE;

ADMINISTRATION, INHALATION; AIR; ANIMALS; BACTERIAL PROTEINS; BONE MARROW; DOSE-RESPONSE RELATIONSHIP, DRUG; ESCHERICHIA COLI PROTEINS; ETHYLENE OXIDE; GERM CELLS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; LUNG; MALE; MICE; MICE, TRANSGENIC; MUTAGENICITY TESTS; MUTATION; REPRESSOR PROTEINS; SEMINIFEROUS TUBULES; SEQUENCE ANALYSIS, DNA; SPLEEN; T-LYMPHOCYTES;

ANIMALIA; MUS MUSCULUS;

EID: 0030807682     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1383-5718(97)00063-6     Document Type: Article

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