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Volumn 36, Issue 6, 1999, Pages 575-655

Physiological roles of the leptin endocrine system: Differences between mice and humans

Author keywords

Adipose tissue; Angiogenesis; Brown adipose tissue; Circadian; Energy balance; Hematopoiesis; Humans; Immune responses; Insulin; Mice; Neonate; Obesity; Pulsatility; Sleep; Starvation; Sympathetic nervous system; Thermoregulation; Torpor

Indexed keywords

LEPTIN; LEPTIN RECEPTOR; TESTOSTERONE;

EID: 0033391940     PISSN: 10408363     EISSN: None     Source Type: Journal    
DOI: 10.1080/10408369991239259     Document Type: Review
Times cited : (144)

References (441)
  • 1
    • 0031978142 scopus 로고    scopus 로고
    • Leptin, leptin receptors, and the control of body weight
    • 1. Friedman JM. Leptin, leptin receptors, and the control of body weight. Nutr Rev 1998; 56: S38-S46.
    • (1998) Nutr Rev , vol.56
    • Friedman, J.M.1
  • 2
    • 0032558725 scopus 로고    scopus 로고
    • Leptin and the regulation of body weight in mammals
    • 2. Friedman JM, Halaas JL. Leptin and the regulation of body weight in mammals. Nature 1998; 395: 763-770.
    • (1998) Nature , vol.395 , pp. 763-770
    • Friedman, J.M.1    Halaas, J.L.2
  • 3
    • 0030942844 scopus 로고    scopus 로고
    • The leptin receptor
    • 3. Tartaglia LA. The leptin receptor. J Biol Chem 1997; 272: 6093-6096.
    • (1997) J Biol Chem , vol.272 , pp. 6093-6096
    • Tartaglia, L.A.1
  • 4
    • 0032065645 scopus 로고    scopus 로고
    • What's in a name? In search of leptin's physiologic role
    • 4. Flier JS. What's in a name? In search of leptin's physiologic role. J Clin Endocrinol Metab 1998; 83: 1407-1413.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 1407-1413
    • Flier, J.S.1
  • 5
    • 0018139377 scopus 로고
    • Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice
    • 5. Coleman DL. Obese and diabetes: two mutant genes causing diabetes-obesity syndromes in mice. Diabetologia 1978; 14: 141-148.
    • (1978) Diabetologia , vol.14 , pp. 141-148
    • Coleman, D.L.1
  • 6
    • 0032130881 scopus 로고    scopus 로고
    • Overview: Neurobiology of OB protein (leptin)
    • 6. Campfield LA, Smith FJ. Overview: neurobiology of OB protein (leptin). Proc Nutr Soc 1998; 57: 429-440.
    • (1998) Proc Nutr Soc , vol.57 , pp. 429-440
    • Campfield, L.A.1    Smith, F.J.2
  • 7
    • 0030832636 scopus 로고    scopus 로고
    • OB protein: A hormonal controller of central neural networks mediating behavioral, metabolic and neuroendocrine responses
    • 7. Campfield LA, Smith FJ Burn P. OB protein: a hormonal controller of central neural networks mediating behavioral, metabolic and neuroendocrine responses. Endocrinol Metab 1997; 4: 81-102.
    • (1997) Endocrinol Metab , vol.4 , pp. 81-102
    • Campfield, L.A.1    Smith, F.J.2    Burn, P.3
  • 8
    • 0031932674 scopus 로고    scopus 로고
    • To be lean or not to be lean. Is leptin the answer
    • 8. Stephens TW, Caro JF. To be lean or not to be lean. Is leptin the answer. Exp Clin Endocrinol Diabetes 1998; 106: 1-15.
    • (1998) Exp Clin Endocrinol Diabetes , vol.106 , pp. 1-15
    • Stephens, T.W.1    Caro, J.F.2
  • 9
    • 0031435811 scopus 로고    scopus 로고
    • Leptin and the regulation of body weight
    • 9. Considine RV, Caro JF. Leptin and the regulation of body weight. Int J Biochem Cell Biol 1997; 11: 1255-1272.
    • (1997) Int J Biochem Cell Biol , vol.11 , pp. 1255-1272
    • Considine, R.V.1    Caro, J.F.2
  • 10
    • 0032130402 scopus 로고    scopus 로고
    • Regulation of leptin production: A dominant role for the sympathetic nervous system
    • 10. Trayhurn P, Duncan JS, Hoggard N, et al. Regulation of leptin production: a dominant role for the sympathetic nervous system. Proc Nutr Soc 1998; 57: 413-419.
    • (1998) Proc Nutr Soc , vol.57 , pp. 413-419
    • Trayhurn, P.1    Duncan, J.S.2    Hoggard, N.3
  • 11
    • 0033038862 scopus 로고    scopus 로고
    • Leptin: Fundamental aspects
    • 11. Trayhurn P, Hoggard N, Mercer JG, et al. Leptin: fundamental aspects. Int J Obesity 1999; 23: suppl 1, 22-28.
    • (1999) Int J Obesity , vol.23 , Issue.SUPPL. 1 , pp. 22-28
    • Trayhurn, P.1    Hoggard, N.2    Mercer, J.G.3
  • 12
    • 0032956713 scopus 로고    scopus 로고
    • Regulation of body weight in humans
    • 12. Jéquier E, Tappy L. Regulation of body weight in humans. Physiol Rev 1999; 79: 451-480.
    • (1999) Physiol Rev , vol.79 , pp. 451-480
    • Jéquier, E.1    Tappy, L.2
  • 13
    • 0029859099 scopus 로고    scopus 로고
    • Leptin: The tale of an obesity gene
    • 13. Caro JF, Sinha MK, Kolaczynski JW, et al. Leptin: the tale of an obesity gene. Diabetes 1996; 45: 1455-1462.
    • (1996) Diabetes , vol.45 , pp. 1455-1462
    • Caro, J.F.1    Sinha, M.K.2    Kolaczynski, J.W.3
  • 14
    • 0031438686 scopus 로고    scopus 로고
    • Leptin: Its role in obesity and beyond
    • 14. Tritos NA, Mantzoros CS. Leptin: its role in obesity and beyond. Diabetologia 1997; 40: 1371-1379.
    • (1997) Diabetologia , vol.40 , pp. 1371-1379
    • Tritos, N.A.1    Mantzoros, C.S.2
  • 16
    • 0031767057 scopus 로고    scopus 로고
    • Leptin: In search of role(s) in human physiology and pathophysiology
    • 16. Mantzoros CS, Moschos SJ. Leptin: in search of role(s) in human physiology and pathophysiology. Clin Endocrinol 1998; 49: 551-567.
    • (1998) Clin Endocrinol , vol.49 , pp. 551-567
    • Mantzoros, C.S.1    Moschos, S.J.2
  • 17
    • 0031436148 scopus 로고    scopus 로고
    • Divergent signaling capacities of the long and short isoforms of the leptin receptor
    • 17. Bjørboek C, Uotani S, da Silva B, et al. Divergent signaling capacities of the long and short isoforms of the leptin receptor. J Biol Chem 1997; 272: 32686-32695.
    • (1997) J Biol Chem , vol.272 , pp. 32686-32695
    • Bjørboek, C.1    Uotani, S.2    Da Silva, B.3
  • 18
    • 0033008075 scopus 로고    scopus 로고
    • Functional properties of leptin receptor isoforms. Internalization and degradation of leptin and ligand-induced receptor downregulation
    • 18. Uotani S, Bjørbaek C, Tornøe J, et al. Functional properties of leptin receptor isoforms. Internalization and degradation of leptin and ligand-induced receptor downregulation. Diabetes 1999; 48: 279-286.
    • (1999) Diabetes , vol.48 , pp. 279-286
    • Uotani, S.1    Bjørbaek, C.2    Tornøe, J.3
  • 19
    • 0032968748 scopus 로고    scopus 로고
    • Leptin and the hypothalamus; neuroendocrine regulation of food intake
    • 19. Mantzoros CS. Leptin and the hypothalamus; neuroendocrine regulation of food intake. Mol Psychiatry 1999; 4: 8-12.
    • (1999) Mol Psychiatry , vol.4 , pp. 8-12
    • Mantzoros, C.S.1
  • 20
    • 0033586747 scopus 로고    scopus 로고
    • The role of leptin in human obesity and disease: A review of current evidence
    • 20. Mantzoros CS. The role of leptin in human obesity and disease: a review of current evidence. Ann Intern Med 1999; 130: 671-680.
    • (1999) Ann Intern Med , vol.130 , pp. 671-680
    • Mantzoros, C.S.1
  • 21
    • 0030878110 scopus 로고    scopus 로고
    • Congenital leptin deficiency is associated with severe early-onset obesity in humans
    • 21. Montague CT, Farooqi IS, Whitehead JP, et al. Congenital leptin deficiency is associated with severe early-onset obesity in humans. Nature 1997; 387: 903-908.
    • (1997) Nature , vol.387 , pp. 903-908
    • Montague, C.T.1    Farooqi, I.S.2    Whitehead, J.P.3
  • 23
    • 0032568376 scopus 로고    scopus 로고
    • Life without leptin
    • 23. O'Rahilly S. Life without leptin. Nature 1998; 330-331.
    • (1998) Nature , pp. 330-331
    • O'Rahilly, S.1
  • 24
    • 0032014836 scopus 로고    scopus 로고
    • A leptin missense mutation associated with hypogonadism and morbid obesity
    • 24. Strobel A, Issad T, Camoin L, et al. A leptin missense mutation associated with hypogonadism and morbid obesity. Nat Genet 1998; 18: 213-215.
    • (1998) Nat Genet , vol.18 , pp. 213-215
    • Strobel, A.1    Issad, T.2    Camoin, L.3
  • 25
    • 0033022224 scopus 로고    scopus 로고
    • Truncated human leptin (Δ133) associated with extreme obesity undergoes proteasomal degradation after defective intracellular transport
    • 25. Rau H, Reaves BJ, O'Rahilly S, et al. Truncated human leptin (Δ133) associated with extreme obesity undergoes proteasomal degradation after defective intracellular transport. Endocrinology 1999; 140: 1718-1723.
    • (1999) Endocrinology , vol.140 , pp. 1718-1723
    • Rau, H.1    Reaves, B.J.2    O'Rahilly, S.3
  • 26
    • 0344450708 scopus 로고    scopus 로고
    • A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction
    • 26. Clément K, Vaisse C, Lahlou N, et al. A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction. Nature 1998; 392:398-401.
    • (1998) Nature , vol.392 , pp. 398-401
    • Clément, K.1    Vaisse, C.2    Lahlou, N.3
  • 27
    • 0033015759 scopus 로고    scopus 로고
    • Leptin and the genetics of obesity
    • 27. Clément K. Leptin and the genetics of obesity. Acta Paediatr 1999; Suppl 428: 51-57.
    • (1999) Acta Paediatr , Issue.SUPPL. 428 , pp. 51-57
    • Clément, K.1
  • 28
    • 0021965216 scopus 로고
    • Mammalian reproduction: An ecological perspective
    • 28. Bronson FH. Mammalian reproduction: an ecological perspective. Biol Reprod 1985; 32: 1-26.
    • (1985) Biol Reprod , vol.32 , pp. 1-26
    • Bronson, F.H.1
  • 29
    • 0022499326 scopus 로고
    • Food restriction and reproductive development: Male and female mice and male rats
    • 29. Hamilton GD, Bronson FH. Food restriction and reproductive development: male and female mice and male rats. Am J Physiol 1986; 250: R370-R376.
    • (1986) Am J Physiol , vol.250
    • Hamilton, G.D.1    Bronson, F.H.2
  • 30
    • 0030470667 scopus 로고    scopus 로고
    • Leptin reduces juvenile fat stores by altering the circadian cycle of energy expenditure
    • 30. Stehling O, Döring H, Ertl J, et al. Leptin reduces juvenile fat stores by altering the circadian cycle of energy expenditure. Am J Physiol 1996; 271: R1770-R1774.
    • (1996) Am J Physiol , vol.271
    • Stehling, O.1    Döring, H.2    Ertl, J.3
  • 31
    • 0031984616 scopus 로고    scopus 로고
    • Leptin selectively increases energy expenditure of food-restricted lean mice
    • 31. Döhring H, Schwarzer K, Nuesslein-Hildesheim B, et al. Leptin selectively increases energy expenditure of food-restricted lean mice. Int J Obesity 1998; 22: 83-88.
    • (1998) Int J Obesity , vol.22 , pp. 83-88
    • Döhring, H.1    Schwarzer, K.2    Nuesslein-Hildesheim, B.3
  • 32
    • 0030920206 scopus 로고    scopus 로고
    • Leptin increases energy expenditure and selectively promotes fat metabolism in ob/ob mice
    • 32. Hwa JJ, Fawzi AB, Graziano MP, et al. Leptin increases energy expenditure and selectively promotes fat metabolism in ob/ob mice. Am J Physiol 1997; 272: R1204-R1209.
    • (1997) Am J Physiol , vol.272
    • Hwa, J.J.1    Fawzi, A.B.2    Graziano, M.P.3
  • 33
    • 0030737953 scopus 로고    scopus 로고
    • Physiological response to long-term peripheral and central leptin infusion in lean and obese mice
    • 33. Halaas JL, Boozer C, Blair-West J, et al. Physiological response to long-term peripheral and central leptin infusion in lean and obese mice. Proc Natl Acad Sci USA 1997; 94: 8878-8883.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 8878-8883
    • Halaas, J.L.1    Boozer, C.2    Blair-West, J.3
  • 34
    • 0032931966 scopus 로고    scopus 로고
    • Effect of the genetic background on the reproduction of leptin-deficient obese mice
    • 34. Ewart-Toland A, Mounzih K, Qui J, et al. Effect of the genetic background on the reproduction of leptin-deficient obese mice. Endocrinology 1999; 140: 732-738.
    • (1999) Endocrinology , vol.140 , pp. 732-738
    • Ewart-Toland, A.1    Mounzih, K.2    Qui, J.3
  • 35
    • 0021969502 scopus 로고
    • Food restriction and reproductive development in wild house mice
    • 35. Hamilton GD, Bronson FH. Food restriction and reproductive development in wild house mice. Biol Reprod 1985; 32: 773-778.
    • (1985) Biol Reprod , vol.32 , pp. 773-778
    • Hamilton, G.D.1    Bronson, F.H.2
  • 36
    • 0031665979 scopus 로고    scopus 로고
    • Increased OB gene expression leads to elevated plasma leptin concentrations in patients with chronic primary hyperinsulinemia
    • 36. D'Adamo M, Buongiorno A, Maroccia E, et al. Increased OB gene expression leads to elevated plasma leptin concentrations in patients with chronic primary hyperinsulinemia. Diabetes 1998; 47: 1625-1629.
    • (1998) Diabetes , vol.47 , pp. 1625-1629
    • D'Adamo, M.1    Buongiorno, A.2    Maroccia, E.3
  • 37
    • 0029665017 scopus 로고    scopus 로고
    • Acute and chronic effect of insulin on leptin production in humans
    • 37. Kolaczynski JW, Nyce MR, Considine RV, et al. Acute and chronic effect of insulin on leptin production in humans. Diabetes 1996; 45: 699-701.
    • (1996) Diabetes , vol.45 , pp. 699-701
    • Kolaczynski, J.W.1    Nyce, M.R.2    Considine, R.V.3
  • 38
    • 0030859484 scopus 로고    scopus 로고
    • Plasma leptin responses to fasting in Pima Indians
    • 38. Pratley RE, Nicolson M, Bogardus C, et al. Plasma leptin responses to fasting in Pima Indians. Am J Physiol 1997; 273: E644-E649.
    • (1997) Am J Physiol , vol.273
    • Pratley, R.E.1    Nicolson, M.2    Bogardus, C.3
  • 39
    • 0030885398 scopus 로고    scopus 로고
    • Entrainment of the diurnal rhythm of plasma leptin to meal timing
    • 39. Schoeller DA, Cella LK, Sinha MK, et al. Entrainment of the diurnal rhythm of plasma leptin to meal timing. J Clin Invest 1997; 100: 1882-1887.
    • (1997) J Clin Invest , vol.100 , pp. 1882-1887
    • Schoeller, D.A.1    Cella, L.K.2    Sinha, M.K.3
  • 40
    • 0032908236 scopus 로고    scopus 로고
    • Regulation of average 24h human plasma leptin level; The influence of exercise and physiological changes in energy balance
    • 40. Van Aggel-Leijssen DPC, van Baak MA, Tenenbaum R, et al. Regulation of average 24h human plasma leptin level; the influence of exercise and physiological changes in energy balance. Int J Obesity 1999; 23: 151-158.
    • (1999) Int J Obesity , vol.23 , pp. 151-158
    • Van Aggel-Leijssen, D.P.C.1    Van Baak, M.A.2    Tenenbaum, R.3
  • 41
    • 16944364768 scopus 로고    scopus 로고
    • Human leptin levels are pulsatile and inversely related to pituitary-adrenal function
    • 41. Licinio J, Mantzoros C, Negrão AB, et al. Human leptin levels are pulsatile and inversely related to pituitary-adrenal function. Nat Med 1997; 3: 575-579.
    • (1997) Nat Med , vol.3 , pp. 575-579
    • Licinio, J.1    Mantzoros, C.2    Negrão, A.B.3
  • 42
    • 15144356418 scopus 로고    scopus 로고
    • Sex differences in circulating human leptin pulse amplitude: Clinical implications
    • 42. Licinio J, Negrão AB, Mantzoros C, et al. Sex differences in circulating human leptin pulse amplitude: clinical implications. J Clin Endocrinol Metab 1998; 83: 4140-4147.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 4140-4147
    • Licinio, J.1    Negrão, A.B.2    Mantzoros, C.3
  • 43
    • 13144293061 scopus 로고    scopus 로고
    • Synchronicity of frequently sampled, 24-h concentrations of circulating leptin, luteinizing hormone, and estradiol in healthy women
    • 43. Licinio J, Negrão AB, Mantzoros C, et al. Synchronicity of frequently sampled, 24-h concentrations of circulating leptin, luteinizing hormone, and estradiol in healthy women. Proc Natl Acad Sci USA 1998; 95: 2541-2546.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 2541-2546
    • Licinio, J.1    Negrão, A.B.2    Mantzoros, C.3
  • 44
    • 0031937520 scopus 로고    scopus 로고
    • Serum leptin and insulin concentrations in patients with insulinoma before and after surgery
    • 44. Popovic V, Micic D, Danjanovic S, et al. Serum leptin and insulin concentrations in patients with insulinoma before and after surgery. Eur J Endocrinol 1998; 138: 86-88.
    • (1998) Eur J Endocrinol , vol.138 , pp. 86-88
    • Popovic, V.1    Micic, D.2    Danjanovic, S.3
  • 46
    • 0032554469 scopus 로고    scopus 로고
    • Leptin in human plasma is derived in part from the brain, and cleared by the kidneys
    • 46. Esler M, Vaz M, Collier G, et al. Leptin in human plasma is derived in part from the brain, and cleared by the kidneys. Lancet 1998; 351: 879.
    • (1998) Lancet , vol.351 , pp. 879
    • Esler, M.1    Vaz, M.2    Collier, G.3
  • 48
    • 17344372906 scopus 로고    scopus 로고
    • High expression of leptin by human bone marrow adipocytes in primary culture
    • 48. Laharrague P, Larrouy D, Fontanilles A-M, et al. High expression of leptin by human bone marrow adipocytes in primary culture. FASEB J 1998; 12: 747-752.
    • (1998) FASEB J , vol.12 , pp. 747-752
    • Laharrague, P.1    Larrouy, D.2    Fontanilles, A.-M.3
  • 49
    • 0032552112 scopus 로고    scopus 로고
    • The stomach is a source of leptin
    • 49. Bado A, Levasseur S, Attoub S, et al. The stomach is a source of leptin. Nature 1998; 394: 790-793.
    • (1998) Nature , vol.394 , pp. 790-793
    • Bado, A.1    Levasseur, S.2    Attoub, S.3
  • 51
    • 18844478150 scopus 로고    scopus 로고
    • Placental leptin: An important new growth factor in intrauterine and neonatal development?
    • 51. Hassink, SG, de Lancey E, Sheslow DV, et al. Placental leptin: an important new growth factor in intrauterine and neonatal development? Pediatrics 1997; 100: el. (http:// www.pediatrics.org/cgi/contents/full/100/1/e1).
    • (1997) Pediatrics , vol.100
    • Hassink, S.G.1    De Lancey, E.2    Sheslow, D.V.3
  • 52
    • 0030866843 scopus 로고    scopus 로고
    • Nonadipose tissue production of leptin: Leptin as a novel placenta-derived hormone in humans
    • 52. Masuzaki H, Ogawa Y, Sagawa N, et al. Nonadipose tissue production of leptin: leptin as a novel placenta-derived hormone in humans. Nat Med 1997; 3: 1029-1033.
    • (1997) Nat Med , vol.3 , pp. 1029-1033
    • Masuzaki, H.1    Ogawa, Y.2    Sagawa, N.3
  • 53
    • 0031920422 scopus 로고    scopus 로고
    • Overexpression of placental leptin in diabetic pregnancy. A critical role for insulin
    • 53. Lepercq J, Cauzac M, Lahlou N, et al. Overexpression of placental leptin in diabetic pregnancy. A critical role for insulin. Diabetes 1998; 47: 847-850.
    • (1998) Diabetes , vol.47 , pp. 847-850
    • Lepercq, J.1    Cauzac, M.2    Lahlou, N.3
  • 54
    • 0031833656 scopus 로고    scopus 로고
    • A positive umbilical venous-arterial difference of leptin level and its rapid decline after birth
    • 54. Yura S, Sagawa N, Mise H, et al. A positive umbilical venous-arterial difference of leptin level and its rapid decline after birth. Am J Obstet Gynecol 1998; 178: 926-930.
    • (1998) Am J Obstet Gynecol , vol.178 , pp. 926-930
    • Yura, S.1    Sagawa, N.2    Mise, H.3
  • 55
    • 0031157855 scopus 로고    scopus 로고
    • The expression of leptin and its receptors in pre-ovulatory human follicles
    • 55. Cioffi JA, Van Blerkom J, Antczak M, et al. The expression of leptin and its receptors in pre-ovulatory human follicles. Mol Hum Reprod 1997; 3: 467-472.
    • (1997) Mol Hum Reprod , vol.3 , pp. 467-472
    • Cioffi, J.A.1    Van Blerkom, J.2    Antczak, M.3
  • 56
    • 0031724837 scopus 로고    scopus 로고
    • Leptin expression in human mammary epithelial cells and breast milk
    • 56. Smith-Kirwin SM, O'Connor DM, Johnston J, et al. Leptin expression in human mammary epithelial cells and breast milk. J Clin Endocrinol Metab 1998; 83: 1810-1813
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 1810-1813
    • Smith-Kirwin, S.M.1    O'Connor, D.M.2    Johnston, J.3
  • 57
    • 0030777965 scopus 로고    scopus 로고
    • Presence of leptin in colostrum and/or breast milk from lactating mothers: A potential role in the regulation of neonatal food intake
    • 57. Casabiell X, Piñeiro V, Tomé MA, et al. Presence of leptin in colostrum and/or breast milk from lactating mothers: a potential role in the regulation of neonatal food intake. J Clin Endocrinol Metab 1997; 82: 4270-4273.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 4270-4273
    • Casabiell, X.1    Piñeiro, V.2    Tomé, M.A.3
  • 58
    • 0031587440 scopus 로고    scopus 로고
    • Leptin is present in human milk and is related to maternal plasma leptin concentration and adiposity
    • 58. Houseknecht KL, McGuire MK, Portocarrero CP, et al. Leptin is present in human milk and is related to maternal plasma leptin concentration and adiposity. Biochem Biophys Res Commun 1997; 240: 742-747.
    • (1997) Biochem Biophys Res Commun , vol.240 , pp. 742-747
    • Houseknecht, K.L.1    McGuire, M.K.2    Portocarrero, C.P.3
  • 59
    • 0033023477 scopus 로고    scopus 로고
    • Increased circulating leptin in alcoholic cirrhosis: Relation to release and disposal
    • 59. Henriksen JH, Holst JJ, Møller S, et al. Increased circulating leptin in alcoholic cirrhosis: relation to release and disposal. Hepatology 1999; 29: 1818-1824.
    • (1999) Hepatology , vol.29 , pp. 1818-1824
    • Henriksen, J.H.1    Holst, J.J.2    Møller, S.3
  • 60
    • 0032489223 scopus 로고    scopus 로고
    • Transdifferentiation of rat hepatic stellate cells results in leptin expression
    • 60. Potter JJ, Womack L, Mezey E, et al. Transdifferentiation of rat hepatic stellate cells results in leptin expression. Biochem Biophys Res Commun 1998; 244: 178-182.
    • (1998) Biochem Biophys Res Commun , vol.244 , pp. 178-182
    • Potter, J.J.1    Womack, L.2    Mezey, E.3
  • 61
    • 0031711553 scopus 로고    scopus 로고
    • Gender-dependent alterations in serum leptin in alcoholic cirrhosis
    • 61. McCullough AJ, Bugianesi E, Marchesini G, et al. Gender-dependent alterations in serum leptin in alcoholic cirrhosis. Gastroenterology 1998; 115: 947-953.
    • (1998) Gastroenterology , vol.115 , pp. 947-953
    • McCullough, A.J.1    Bugianesi, E.2    Marchesini, G.3
  • 62
    • 0031711787 scopus 로고    scopus 로고
    • Leptin, obesity and liver disease
    • 62. Kaplan LM. Leptin, obesity and liver disease. Gastroenterology 1998; 115: 997-1001.
    • (1998) Gastroenterology , vol.115 , pp. 997-1001
    • Kaplan, L.M.1
  • 63
    • 0032514941 scopus 로고    scopus 로고
    • Expression of specific white adipose tissue genes in denervation-induced skeletal muscle fatty degeneration
    • 63. Dulor J-P, Cambon B, Vigneron P, et al. Expression of specific white adipose tissue genes in denervation-induced skeletal muscle fatty degeneration. FEBS Lett 1998; 439: 89-92.
    • (1998) FEBS Lett , vol.439 , pp. 89-92
    • Dulor, J.-P.1    Cambon, B.2    Vigneron, P.3
  • 64
    • 0033525137 scopus 로고    scopus 로고
    • Leptin immunoreactivity in the central nervous system in normal and diabetic rats
    • 64. Li H-Y, Wang L-L Yeh R-S. Leptin immunoreactivity in the central nervous system in normal and diabetic rats. Neuroreport 1999; 10: 437-442.
    • (1999) Neuroreport , vol.10 , pp. 437-442
    • Li, H.-Y.1    Wang, L.-L.2    Yeh, R.-S.3
  • 65
    • 0029974877 scopus 로고    scopus 로고
    • Adipose tissue leptin production and plasma leptin kinetics in humans
    • 65. Klein S, Coppack SW, Mohamed-Ali V, et al. Adipose tissue leptin production and plasma leptin kinetics in humans. Diabetes 1996; 45: 984-987.
    • (1996) Diabetes , vol.45 , pp. 984-987
    • Klein, S.1    Coppack, S.W.2    Mohamed-Ali, V.3
  • 66
    • 0029822048 scopus 로고    scopus 로고
    • Leptin is cleared from the circulation primarily by the kidney
    • 66. Cumin F, Baum H-P Levens N. Leptin is cleared from the circulation primarily by the kidney. Int J Obesity 1996; 20: 1120-1126.
    • (1996) Int J Obesity , vol.20 , pp. 1120-1126
    • Cumin, F.1    Baum, H.-P.2    Levens, N.3
  • 67
    • 0031426378 scopus 로고    scopus 로고
    • Whole body leptin kinetics and renal metabolism in vivo
    • 67. Zeng J, Patterson BW, Klein S, et al. Whole body leptin kinetics and renal metabolism in vivo. Am J Physiol 1997; 273: E1102-E1106.
    • (1997) Am J Physiol , vol.273
    • Zeng, J.1    Patterson, B.W.2    Klein, S.3
  • 68
    • 0031766571 scopus 로고    scopus 로고
    • Plasma leptin turnover rates in lean and obese Zucker rats
    • 68. Vila R, Adan C, Rafecas I, et al. Plasma leptin turnover rates in lean and obese Zucker rats. Endocrinology 1998; 139: 4466-4469.
    • (1998) Endocrinology , vol.139 , pp. 4466-4469
    • Vila, R.1    Adan, C.2    Rafecas, I.3
  • 69
    • 0031827918 scopus 로고    scopus 로고
    • Leptin: Its pharmacokinetics and tissue distribution
    • 69. Hill RA, Margetic S, Pegg GG, et al. Leptin: its pharmacokinetics and tissue distribution. Int J Obesity 1998; 22: 765-770.
    • (1998) Int J Obesity , vol.22 , pp. 765-770
    • Hill, R.A.1    Margetic, S.2    Pegg, G.G.3
  • 70
    • 0029896530 scopus 로고    scopus 로고
    • Role of leptin in the neuroendocrine response to fasting
    • 70. Ahima RS, Prabakaran D, Mantzoros C, et al. Role of leptin in the neuroendocrine response to fasting. Nature 1996; 382: 250-252.
    • (1996) Nature , vol.382 , pp. 250-252
    • Ahima, R.S.1    Prabakaran, D.2    Mantzoros, C.3
  • 71
    • 0030875272 scopus 로고    scopus 로고
    • Recombinant leptin exchanges between parabiosed mice but does not reach equilibrium
    • 71. Harris RBS, Zhou J, Weigle DS, et al. Recombinant leptin exchanges between parabiosed mice but does not reach equilibrium. Am J Physiol 1997; 272: R1800-R1808.
    • (1997) Am J Physiol , vol.272
    • Harris, R.B.S.1    Zhou, J.2    Weigle, D.S.3
  • 72
    • 0030807358 scopus 로고    scopus 로고
    • Diet-induced obese mice develop peripheral, but not central, resistance to leptin
    • 72. Van Heek M, Compton DS, France CF, et al. Diet-induced obese mice develop peripheral, but not central, resistance to leptin. J Clin Invest 1997; 99: 385-390.
    • (1997) J Clin Invest , vol.99 , pp. 385-390
    • Van Heek, M.1    Compton, D.S.2    France, C.F.3
  • 73
    • 0031890721 scopus 로고    scopus 로고
    • Severe leptin resistance in brown fat-deficient uncoupling protein promoter-driven diphtheria toxin A mice despite suppression of hypothalamic neuropeptide Y and circulating corticosterone concentrations
    • 73. Mantzoros CS, Frederich RC, Qu D, et al. Severe leptin resistance in brown fat-deficient uncoupling protein promoter-driven diphtheria toxin A mice despite suppression of hypothalamic neuropeptide Y and circulating corticosterone concentrations. Diabetes 1998; 47: 230-238.
    • (1998) Diabetes , vol.47 , pp. 230-238
    • Mantzoros, C.S.1    Frederich, R.C.2    Qu, D.3
  • 75
    • 0030832868 scopus 로고    scopus 로고
    • Mechanism of leptin removal from the circulation by the kidney
    • 75. Cumin F, Baum H-P Levens N. Mechanism of leptin removal from the circulation by the kidney. J Endocrinol 1997; 155: 577-585.
    • (1997) J Endocrinol , vol.155 , pp. 577-585
    • Cumin, F.1    Baum, H.-P.2    Levens, N.3
  • 76
    • 0030722564 scopus 로고    scopus 로고
    • Role of the kidney in human leptin metabolism
    • 76. Meyer C, Robson D, Rackovsky N, et al. Role of the kidney in human leptin metabolism. Am J Physiol 1997; 273: E903-E907.
    • (1997) Am J Physiol , vol.273
    • Meyer, C.1    Robson, D.2    Rackovsky, N.3
  • 77
    • 0030936047 scopus 로고    scopus 로고
    • The metabolic significance of leptin in humans: Gender-based differences in relationship to adiposity, insulin sensitivity, and energy expenditure
    • 77. Kennedy A, Gettys TW, Watson P, et al. The metabolic significance of leptin in humans: gender-based differences in relationship to adiposity, insulin sensitivity, and energy expenditure. J Clin Endocrinol Metab 1997; 82: 1293-1300.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 1293-1300
    • Kennedy, A.1    Gettys, T.W.2    Watson, P.3
  • 78
    • 0030273715 scopus 로고    scopus 로고
    • Gender differences in serum leptin levels in humans
    • 78. Hickey MS, Israel RG, Gardiner SN, et al. Gender differences in serum leptin levels in humans. Biochem Mol Med 1996; 59: 1-6.
    • (1996) Biochem Mol Med , vol.59 , pp. 1-6
    • Hickey, M.S.1    Israel, R.G.2    Gardiner, S.N.3
  • 79
    • 0030895336 scopus 로고    scopus 로고
    • Gender-dependent effects of exercise training on serum leptin levels in humans
    • 79. Hickey MS, Houmard JA, Considine RV, et al. Gender-dependent effects of exercise training on serum leptin levels in humans. Am J Physiol 1997; 272: E562-E566.
    • (1997) Am J Physiol , vol.272
    • Hickey, M.S.1    Houmard, J.A.2    Considine, R.V.3
  • 80
    • 0031953285 scopus 로고    scopus 로고
    • Gender differences in plasma leptin concentration are not influenced by menopause or hormone replacement therapy
    • 80. Hickey MS, Gardiner SN, Thomson DP, et al. Gender differences in plasma leptin concentration are not influenced by menopause or hormone replacement therapy. Med Sci Res 1998; 26: 271-273.
    • (1998) Med Sci Res , vol.26 , pp. 271-273
    • Hickey, M.S.1    Gardiner, S.N.2    Thomson, D.P.3
  • 82
    • 0030966660 scopus 로고    scopus 로고
    • Relationship between circulating leptin and peripheral fat distribution in obese subjects
    • 82. Lönnqvist F, Wennlund A Arner P. Relationship between circulating leptin and peripheral fat distribution in obese subjects. Int J Obesity 1997; 21: 255-260.
    • (1997) Int J Obesity , vol.21 , pp. 255-260
    • Lönnqvist, F.1    Wennlund, A.2    Arner, P.3
  • 83
    • 1842413691 scopus 로고    scopus 로고
    • Leptin secretion from adipose tissue in women. Relationship to plasma levels and gene expression
    • 83. Lönnqvist F, Nordfors L, Jansson M, et al. Leptin secretion from adipose tissue in women. Relationship to plasma levels and gene expression. J Clin Invest 1997; 99: 2398-2404.
    • (1997) J Clin Invest , vol.99 , pp. 2398-2404
    • Lönnqvist, F.1    Nordfors, L.2    Jansson, M.3
  • 84
    • 0030784421 scopus 로고    scopus 로고
    • Leptin concentration in women is influenced by regional distribution of adipose tissue
    • 84. Bennett FI, McFarlane-Anderson N, Wilks R, et al. Leptin concentration in women is influenced by regional distribution of adipose tissue. Am J Clin Nutr 1997; 66: 1340-1344.
    • (1997) Am J Clin Nutr , vol.66 , pp. 1340-1344
    • Bennett, F.I.1    McFarlane-Anderson, N.2    Wilks, R.3
  • 85
    • 0033128246 scopus 로고    scopus 로고
    • Collection and interpretaion of plasma leptin concentration data in humans
    • 85. Jensen MD, Hensrud D, O'Brien PC, et al. Collection and interpretaion of plasma leptin concentration data in humans. Obesity Res 1999; 7: 241-245.
    • (1999) Obesity Res , vol.7 , pp. 241-245
    • Jensen, M.D.1    Hensrud, D.2    O'Brien, P.C.3
  • 86
    • 0031802865 scopus 로고    scopus 로고
    • Leptin secretion from subcutaneous and visceral adipose tissue in women
    • 86. Van Harmelen V, Reynisdottir S, Eriksson P, et al. Leptin secretion from subcutaneous and visceral adipose tissue in women. Diabetes 1998; 47: 913-917.
    • (1998) Diabetes , vol.47 , pp. 913-917
    • Van Harmelen, V.1    Reynisdottir, S.2    Eriksson, P.3
  • 87
    • 0031054698 scopus 로고    scopus 로고
    • Depot-and sex-specific differences in human leptin mRNA expression. Implications for the control of regional fat distribution
    • 87. Montague CT, Prins JB, Sanders L, et al. Depot-and sex-specific differences in human leptin mRNA expression. Implications for the control of regional fat distribution. Diabetes 1997; 46: 342-347.
    • (1997) Diabetes , vol.46 , pp. 342-347
    • Montague, C.T.1    Prins, J.B.2    Sanders, L.3
  • 88
    • 0030739466 scopus 로고    scopus 로고
    • Circulating leptin in women: A longitudinal study in the menstrual cycle and during pregnancy
    • 88. Hardie L, Trayhurn P, Abramovich D, et al. Circulating leptin in women: a longitudinal study in the menstrual cycle and during pregnancy. Clin Endocrinol 1997; 47: 101-106.
    • (1997) Clin Endocrinol , vol.47 , pp. 101-106
    • Hardie, L.1    Trayhurn, P.2    Abramovich, D.3
  • 89
    • 0031811443 scopus 로고    scopus 로고
    • Leptin concentrations in the follicular phase of spontaneous cycles and cycles superovulated with follicle stimulating hormone
    • 89. Messinis IE, Milingos S, Zikopoulos K, et al. Leptin concentrations in the follicular phase of spontaneous cycles and cycles superovulated with follicle stimulating hormone. Hum Reprod 1998; 13: 1152-1156.
    • (1998) Hum Reprod , vol.13 , pp. 1152-1156
    • Messinis, I.E.1    Milingos, S.2    Zikopoulos, K.3
  • 90
    • 0032916638 scopus 로고    scopus 로고
    • Leptin concentrations in normal women following bilateral ovariectomy
    • 90. Messinis IE, Milingos SD, Alexandris E, et al. Leptin concentrations in normal women following bilateral ovariectomy. Hum Reprod 1999; 14: 913-918.
    • (1999) Hum Reprod , vol.14 , pp. 913-918
    • Messinis, I.E.1    Milingos, S.D.2    Alexandris, E.3
  • 91
  • 92
    • 0032945043 scopus 로고    scopus 로고
    • Serum leptin levels during the menstrual cycle of healthy fertile women
    • 92. Quinton ND, Laird SM, Okon MA, et al. Serum leptin levels during the menstrual cycle of healthy fertile women. Br J Biomed Sci 1999; 56: 16-19.
    • (1999) Br J Biomed Sci , vol.56 , pp. 16-19
    • Quinton, N.D.1    Laird, S.M.2    Okon, M.A.3
  • 93
    • 0031930777 scopus 로고    scopus 로고
    • Plasma sex hormones are significantly associated with plasma leptin concentration in healthy subjects
    • 93. Paolisso G, Rizzo MR, Mone CM, et al. Plasma sex hormones are significantly associated with plasma leptin concentration in healthy subjects. Clin Endocrinol 1998; 48: 291-297.
    • (1998) Clin Endocrinol , vol.48 , pp. 291-297
    • Paolisso, G.1    Rizzo, M.R.2    Mone, C.M.3
  • 94
    • 0031741597 scopus 로고    scopus 로고
    • Inverse correlation between serum testosterone and leptin in men
    • 94. Luukkaa V, Pesonen U, Huhtaniemi I, et al. Inverse correlation between serum testosterone and leptin in men. J Clin Endocrinol Metab 1998; 83: 3243-3246.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 3243-3246
    • Luukkaa, V.1    Pesonen, U.2    Huhtaniemi, I.3
  • 95
    • 0030742514 scopus 로고    scopus 로고
    • Serum leptin concentrations in a normal population and in GH deficiency: Negative correlation with testosterone in men and effects of GH treatment
    • 95. Nyström F, Ekman B, Österlund M, et al. Serum leptin concentrations in a normal population and in GH deficiency: negative correlation with testosterone in men and effects of GH treatment. Clin Endocrinol 1997; 47: 191-198.
    • (1997) Clin Endocrinol , vol.47 , pp. 191-198
    • Nyström, F.1    Ekman, B.2    Österlund, M.3
  • 96
    • 0030853340 scopus 로고    scopus 로고
    • Testosterone substitution normalizes elevated serum leptin levels in hypogonadal men
    • 96. Jockenhövel F, Blum WF, Vogel E, et al. Testosterone substitution normalizes elevated serum leptin levels in hypogonadal men. J Clin Endocrinol Metab 1997; 82: 2510-2513.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 2510-2513
    • Jockenhövel, F.1    Blum, W.F.2    Vogel, E.3
  • 97
    • 0030796978 scopus 로고    scopus 로고
    • Strong association between serum levels of leptin and testosterone in men
    • 97. Behre HM, Simoni M Nieschlag E. Strong association between serum levels of leptin and testosterone in men. Clin Endocrinol 1997; 47: 237-240.
    • (1997) Clin Endocrinol , vol.47 , pp. 237-240
    • Behre, H.M.1    Simoni, M.2    Nieschlag, E.3
  • 98
    • 0031732996 scopus 로고    scopus 로고
    • The impact of reversible gonadal sex steroid suppression on serum leptin concentrations in children with central precocious puberty
    • 98. Palmert MR, Radovick S Boepple PA. The impact of reversible gonadal sex steroid suppression on serum leptin concentrations in children with central precocious puberty. J Clin Endocrinol Metab 1998; 83: 1091-1096.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 1091-1096
    • Palmert, M.R.1    Radovick, S.2    Boepple, P.A.3
  • 99
    • 0032969688 scopus 로고    scopus 로고
    • Age-related changes in sex hormones affect the sex difference in serum leptin independently of changes in body fat
    • 99. Baumgartner RN, Waters DL, Morley JE, et al. Age-related changes in sex hormones affect the sex difference in serum leptin independently of changes in body fat. Metabolism 1999; 48: 378-384.
    • (1999) Metabolism , vol.48 , pp. 378-384
    • Baumgartner, R.N.1    Waters, D.L.2    Morley, J.E.3
  • 100
    • 0029816596 scopus 로고    scopus 로고
    • Effects of gender, body composition, and menopause on plasma concentrations of leptin
    • 100. Rosenbaum M, Nicolson M, Hirsch J, et al. Effects of gender, body composition, and menopause on plasma concentrations of leptin. J Clin Endocrinol Metab 1996; 81: 3424-3427.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 3424-3427
    • Rosenbaum, M.1    Nicolson, M.2    Hirsch, J.3
  • 101
    • 0030988701 scopus 로고    scopus 로고
    • Circulating leptin in normal children and during the dynamic phase of juvenile obesity. Relation to body fatness, energy metabolism, caloric intake, and sexual dimorphism
    • 101. Lahlou N, Landais P, De Boissieu D, et al. Circulating leptin in normal children and during the dynamic phase of juvenile obesity. Relation to body fatness, energy metabolism, caloric intake, and sexual dimorphism. Diabetes 1997; 46: 989-993.
    • (1997) Diabetes , vol.46 , pp. 989-993
    • Lahlou, N.1    Landais, P.2    De Boissieu, D.3
  • 102
    • 0030838451 scopus 로고    scopus 로고
    • Nocturnal rise of leptin in normal prepubertal and pubertal children and in patients with perinatal stalk-transection syndrome
    • 102. Pombo M, Herrera-Justirriano E, Considine RV, et al. Nocturnal rise of leptin in normal prepubertal and pubertal children and in patients with perinatal stalk-transection syndrome. J Clin Endocrinol Metab 1997; 82: 2751-2754.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 2751-2754
    • Pombo, M.1    Herrera-Justirriano, E.2    Considine, R.V.3
  • 103
    • 0031695844 scopus 로고    scopus 로고
    • Leptin as a metabolic regulator during fetal and neonatal life and in childhood and adolescence
    • 103. Kiess W, Siebler T, Englaro P, et al. Leptin as a metabolic regulator during fetal and neonatal life and in childhood and adolescence. J Pediat Endocrinol Metab 1998; 11: 483-496.
    • (1998) J Pediat Endocrinol Metab , vol.11 , pp. 483-496
    • Kiess, W.1    Siebler, T.2    Englaro, P.3
  • 104
    • 0029746041 scopus 로고    scopus 로고
    • Serum leptin in children with obesity: Relationship to gender and development
    • 104. Hassink SG, Sheslow DV, de Lancey E, et al. Serum leptin in children with obesity: relationship to gender and development. Pediatrics 1996; 98: 201-203.
    • (1996) Pediatrics , vol.98 , pp. 201-203
    • Hassink, S.G.1    Sheslow, D.V.2    De Lancey, E.3
  • 105
    • 0033023891 scopus 로고    scopus 로고
    • Changes in leptin concentration during the early postnatal period: Adjustment to extrauterine life?
    • 105. Hytinantti T, Koistinen HA, Koivisto VA, et al. Changes in leptin concentration during the early postnatal period: adjustment to extrauterine life? Pediatr Res 1999; 45: 197-201.
    • (1999) Pediatr Res , vol.45 , pp. 197-201
    • Hytinantti, T.1    Koistinen, H.A.2    Koivisto, V.A.3
  • 106
    • 0032015933 scopus 로고    scopus 로고
    • Leptin levels in pregnant women and newborn infants: Gender differences and reduction during the neonatal period
    • 106. Helland IB, Reseland JE, Saugstad OD, et al. Leptin levels in pregnant women and newborn infants: gender differences and reduction during the neonatal period. Pediatrics 1998; 101: e12. (http://www.pediatrics.org/cgi/content/full/101/3/e12)
    • (1998) Pediatrics , vol.101
    • Helland, I.B.1    Reseland, J.E.2    Saugstad, O.D.3
  • 107
    • 0033033001 scopus 로고    scopus 로고
    • Role of serum leptin in the regulation of weight gain in early infancy
    • 107. Harigaya A, Onigata K, Nako Y, et al. Role of serum leptin in the regulation of weight gain in early infancy. Biol Neonate 1999; 75: 234-238.
    • (1999) Biol Neonate , vol.75 , pp. 234-238
    • Harigaya, A.1    Onigata, K.2    Nako, Y.3
  • 108
    • 0031980203 scopus 로고    scopus 로고
    • db affects body composition and leptin homeostasis in adult mice
    • db affects body composition and leptin homeostasis in adult mice. Am J Physiol 1998; 274: R985-R990.
    • (1998) Am J Physiol , vol.274
    • Chung, W.K.1    Belfi, K.2    Chua, M.3
  • 109
    • 0032578453 scopus 로고    scopus 로고
    • Abnormal regulation of the leptin gene in the pathogenesis of obesity
    • 109. Ioffe E, Moon B, Connolly E, et al. Abnormal regulation of the leptin gene in the pathogenesis of obesity. Proc Natl Acad Sci USA 1998; 95: 11852-11857.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 11852-11857
    • Ioffe, E.1    Moon, B.2    Connolly, E.3
  • 110
    • 0030918538 scopus 로고    scopus 로고
    • Gain in body fat is inversely related to the nocturnal rise in serum leptin level in young females
    • 110. Matkovic V, Ilich JZ, Badenhop NE, et al. Gain in body fat is inversely related to the nocturnal rise in serum leptin level in young females. J Clin Endocrinol Metab 1997; 82: 1368-1372.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 1368-1372
    • Matkovic, V.1    Ilich, J.Z.2    Badenhop, N.E.3
  • 111
    • 0031839019 scopus 로고    scopus 로고
    • The circadian rhythm of leptin is preserved in growth hormone deficient hypopituitary adults
    • 111. Kousta E, Chrisoulidou A, Lawrence NJ, et al. The circadian rhythm of leptin is preserved in growth hormone deficient hypopituitary adults. Clin Endocrinol 1998; 48: 685-690.
    • (1998) Clin Endocrinol , vol.48 , pp. 685-690
    • Kousta, E.1    Chrisoulidou, A.2    Lawrence, N.J.3
  • 112
    • 0031790350 scopus 로고    scopus 로고
    • Diurnal and ultradian rhythmicity of plasma leptin: Effects of gender and adiposity
    • 112. Saad MF, Riad-Gabriel MG, Khan A, et al. Diurnal and ultradian rhythmicity of plasma leptin: effects of gender and adiposity. J Clin Endocrinol Metab 1998; 83: 453-459.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 453-459
    • Saad, M.F.1    Riad-Gabriel, M.G.2    Khan, A.3
  • 113
    • 0029978426 scopus 로고    scopus 로고
    • Nocturnal rise of leptin in lean, obese, and non-insulin-dependent diabetes mellitus subjects
    • 113. Sinha MK, Ohannesian JP, Heiman ML, et al. Nocturnal rise of leptin in lean, obese, and non-insulin-dependent diabetes mellitus subjects. J Clin Invest 1996; 97: 1344-1347.
    • (1996) J Clin Invest , vol.97 , pp. 1344-1347
    • Sinha, M.K.1    Ohannesian, J.P.2    Heiman, M.L.3
  • 114
    • 0031756365 scopus 로고    scopus 로고
    • Circadian rhythm of plasma leptin levels in upper and lower body obese women: Influence of body fat distribution and weight loss
    • 114. Langendonk JG, Pijl H, Toornvliet AC, et al. Circadian rhythm of plasma leptin levels in upper and lower body obese women: influence of body fat distribution and weight loss. J Clin Endocrinol Metab 1998; 83: 1706-1712.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 1706-1712
    • Langendonk, J.G.1    Pijl, H.2    Toornvliet, A.C.3
  • 115
    • 0031773558 scopus 로고    scopus 로고
    • Circadian plasma leptin levels in patients with anorexia nervosa: Relation to insulin and cortisol
    • 115. Herpertz S, Wagner R, Albers N, et al. Circadian plasma leptin levels in patients with anorexia nervosa: relation to insulin and cortisol. Horm Res 1998; 50: 197-204.
    • (1998) Horm Res , vol.50 , pp. 197-204
    • Herpertz, S.1    Wagner, R.2    Albers, N.3
  • 116
    • 0032977754 scopus 로고    scopus 로고
    • Impact of binge eating on metabolic and leptin dynamics in normal young women
    • 116. Taylor AE, Hubbard J Anderson EJ. Impact of binge eating on metabolic and leptin dynamics in normal young women. J Clin Endocrinol Metab 1999; 84: 428-434.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 428-434
    • Taylor, A.E.1    Hubbard, J.2    Anderson, E.J.3
  • 117
    • 0031851995 scopus 로고    scopus 로고
    • Short term response of circulating leptin to feeding and fasting in man: Influence of circadian cycle
    • 117. Dallongeville J, Hecquet B, Lebel P, et al. Short term response of circulating leptin to feeding and fasting in man: influence of circadian cycle. Int J Obesity 1998; 22: 728-733.
    • (1998) Int J Obesity , vol.22 , pp. 728-733
    • Dallongeville, J.1    Hecquet, B.2    Lebel, P.3
  • 118
    • 0031970859 scopus 로고    scopus 로고
    • Hypoleptinemia in patients with anorexia nervosa: Loss of circadian rhythm and unresponsiveness to short-term refeeding
    • 118. Balligand JL, Brichard SM, Brichard V, et al. Hypoleptinemia in patients with anorexia nervosa: loss of circadian rhythm and unresponsiveness to short-term refeeding. Eur J Endocrinol 1998; 138: 415-420.
    • (1998) Eur J Endocrinol , vol.138 , pp. 415-420
    • Balligand, J.L.1    Brichard, S.M.2    Brichard, V.3
  • 119
    • 0031732715 scopus 로고    scopus 로고
    • Circadian and ultradian variations of leptin in normal man under continuous enterai nutrition: Relationship to sleep and body temperature
    • 119. Simon C, Gronfier C, Schlienger JL, et al. Circadian and ultradian variations of leptin in normal man under continuous enterai nutrition: relationship to sleep and body temperature. J Clin Endocrinol Metab 1998; 83: 1893-1899.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 1893-1899
    • Simon, C.1    Gronfier, C.2    Schlienger, J.L.3
  • 120
    • 0031835911 scopus 로고    scopus 로고
    • Diurnal variation of the serum leptin concentration in patients with anorexia nervosa
    • 120. Støving RK, Vinten J, Handberg A, et al. Diurnal variation of the serum leptin concentration in patients with anorexia nervosa. Clin Endocrinol 1998; 48: 761-768.
    • (1998) Clin Endocrinol , vol.48 , pp. 761-768
    • Støving, R.K.1    Vinten, J.2    Handberg, A.3
  • 121
    • 0033009882 scopus 로고    scopus 로고
    • High-fat meals reduce 24-h circulating leptin concentrations in women
    • 121. Havel PJ, Townsend R, Chaump L, et al. High-fat meals reduce 24-h circulating leptin concentrations in women. Diabetes 1999; 48: 334-341.
    • (1999) Diabetes , vol.48 , pp. 334-341
    • Havel, P.J.1    Townsend, R.2    Chaump, L.3
  • 122
    • 0031738750 scopus 로고    scopus 로고
    • Nutritional and endocrine-metabolic aberrations in women with functional hypothalamic amenorrhea
    • 122. Laughlin GA, Dominguez CE Yen SSC. Nutritional and endocrine-metabolic aberrations in women with functional hypothalamic amenorrhea. J Clin Endocrinol Metab 1998; 83: 25-32.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 25-32
    • Laughlin, G.A.1    Dominguez, C.E.2    Yen, S.S.C.3
  • 123
    • 0031025130 scopus 로고    scopus 로고
    • Hypoleptinemia in women athletes: Absence of a diurnal rhythm with amenorrhea
    • 123. Laughlin GA, Yen SSC. Hypoleptinemia in women athletes: absence of a diurnal rhythm with amenorrhea. J Clin Endocrinol Metab 1997; 82: 318-321.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 318-321
    • Laughlin, G.A.1    Yen, S.S.C.2
  • 124
    • 17144465403 scopus 로고    scopus 로고
    • Serum leptin levels in a patient with pheochromocytoma
    • 124. Sakane N, Yoshida T, Mizutani T, et al. Serum leptin levels in a patient with pheochromocytoma. J Clin Endocrinol Metab 1998; 83: 1400.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 1400
    • Sakane, N.1    Yoshida, T.2    Mizutani, T.3
  • 125
    • 0032944164 scopus 로고    scopus 로고
    • Rapid leptin decrease in immediate post-exercise recovery
    • 125. Duclos M, Corcuff J-B, Ruffie A, et al. Rapid leptin decrease in immediate post-exercise recovery. Clin Endocrinol 1999; 50: 337-342.
    • (1999) Clin Endocrinol , vol.50 , pp. 337-342
    • Duclos, M.1    Corcuff, J.-B.2    Ruffie, A.3
  • 126
    • 0030883332 scopus 로고    scopus 로고
    • Effects of prolonged hyperinsulinemia on serum leptin in normal human subjects
    • 126. Boden G, Chen X, Kolaczynski JW, et al. Effects of prolonged hyperinsulinemia on serum leptin in normal human subjects. J Clin Invest 1997; 100: 1107-1113.
    • (1997) J Clin Invest , vol.100 , pp. 1107-1113
    • Boden, G.1    Chen, X.2    Kolaczynski, J.W.3
  • 127
    • 0025687584 scopus 로고
    • Diurnal and ultradian rhythms in human endocrine function: A minireview
    • 127. Van Cauter E. Diurnal and ultradian rhythms in human endocrine function: a minireview. Horm Res 1990; 34: 45-53.
    • (1990) Horm Res , vol.34 , pp. 45-53
    • Van Cauter, E.1
  • 128
    • 0031933170 scopus 로고    scopus 로고
    • The roles of time of day and sleep quality in modulating glucose regulation: Clinical implications
    • 128. Scheen AJ, Van Cauter E. The roles of time of day and sleep quality in modulating glucose regulation: clinical implications. Horm Res 1998; 49: 191-201.
    • (1998) Horm Res , vol.49 , pp. 191-201
    • Scheen, A.J.1    Van Cauter, E.2
  • 129
    • 0032435159 scopus 로고    scopus 로고
    • Variations in glucocorticoid levels within the physiological range affect plasma leptin levels
    • 129. Elimam A, Knutsson U, Brönnegård M, et al. Variations in glucocorticoid levels within the physiological range affect plasma leptin levels. Eur J Endocrinol 1998; 139: 615-620.
    • (1998) Eur J Endocrinol , vol.139 , pp. 615-620
    • Elimam, A.1    Knutsson, U.2    Brönnegård, M.3
  • 130
    • 0028869620 scopus 로고
    • Diurnal rhythmicity of human cholesterol synthesis: Normal pattern and adaptation to simulated "jet lag"
    • 130. Cella LK, Van Cauter E Schoeller DA. Diurnal rhythmicity of human cholesterol synthesis: normal pattern and adaptation to simulated "jet lag". Am J Physiol 1995; 269: E489-E498.
    • (1995) Am J Physiol , vol.269
    • Cella, L.K.1    Van Cauter, E.2    Schoeller, D.A.3
  • 131
    • 0028867483 scopus 로고
    • Effect of meal timing on diurnal rhythm of human cholesterol synthesis
    • 131. Cella LK, Van Cauter E Schoeller DA. Effect of meal timing on diurnal rhythm of human cholesterol synthesis. Am J Physiol 1995; 269: E878-E883.
    • (1995) Am J Physiol , vol.269
    • Cella, L.K.1    Van Cauter, E.2    Schoeller, D.A.3
  • 132
    • 0030759125 scopus 로고    scopus 로고
    • Nighttime drop in body temperature: A physiological trigger for sleep onset?
    • 132. Murphy PJ, Campbell SS. Nighttime drop in body temperature: a physiological trigger for sleep onset? Sleep 1997; 20: 505-511.
    • (1997) Sleep , vol.20 , pp. 505-511
    • Murphy, P.J.1    Campbell, S.S.2
  • 133
    • 0025062570 scopus 로고
    • Continuous 24-hour assessment of the neural regulation of systemic arterial pressure and RR variabilities in ambulant subjects
    • 133. Furlan R, Guzzetti S, Crivellaro W, et al. Continuous 24-hour assessment of the neural regulation of systemic arterial pressure and RR variabilities in ambulant subjects. Circulation 1990; 81: 537-547.
    • (1990) Circulation , vol.81 , pp. 537-547
    • Furlan, R.1    Guzzetti, S.2    Crivellaro, W.3
  • 134
    • 0025864043 scopus 로고
    • Quantitative analysis of the 24-hour blood pressure and heart rate patterns in young men
    • 134. Degaute J-P, van de Borne P, Linkowski P, et al. Quantitative analysis of the 24-hour blood pressure and heart rate patterns in young men. Hypertension 1991; 18: 199-210.
    • (1991) Hypertension , vol.18 , pp. 199-210
    • Degaute, J.-P.1    Van De Borne, P.2    Linkowski, P.3
  • 135
    • 0019196129 scopus 로고
    • Plasma norepinephrine levels are influenced by sodium intake, glucocorticoid administration, and circadian changes in normal man
    • 135. Stene M, Panagiotis N, Tuck ML, et al. Plasma norepinephrine levels are influenced by sodium intake, glucocorticoid administration, and circadian changes in normal man. J Clin Endocrinol Metab 1980; 51: 1340-1345.
    • (1980) J Clin Endocrinol Metab , vol.51 , pp. 1340-1345
    • Stene, M.1    Panagiotis, N.2    Tuck, M.L.3
  • 136
    • 0021836283 scopus 로고
    • Circadian rhythms of epinephrine and norepinephrine in man
    • 136. Linsell CR, Lightman SL, Mullen PE, et al. Circadian rhythms of epinephrine and norepinephrine in man. J Clin Endocrinol Metab 1985; 60: 1210-1215.
    • (1985) J Clin Endocrinol Metab , vol.60 , pp. 1210-1215
    • Linsell, C.R.1    Lightman, S.L.2    Mullen, P.E.3
  • 137
    • 0018581803 scopus 로고
    • Circadian variation of plasma catecholamines in young and old men: Relation to rapid eye movement and slow wave sleep
    • 137. Prinz PN, Halter J, Benedetti C, et al. Circadian variation of plasma catecholamines in young and old men: relation to rapid eye movement and slow wave sleep. J Clin Endocrinol Metab 1979; 49: 300-304.
    • (1979) J Clin Endocrinol Metab , vol.49 , pp. 300-304
    • Prinz, P.N.1    Halter, J.2    Benedetti, C.3
  • 138
    • 2642605368 scopus 로고    scopus 로고
    • Twenty-four-hour rhythms of plasma catecholamines and their relation to cardiovascular parameters in healthy young men
    • 138. Schöfl C, Becker C, Prank K, et al. Twenty-four-hour rhythms of plasma catecholamines and their relation to cardiovascular parameters in healthy young men. Eur J Endocrinol 1997; 137: 675-683.
    • (1997) Eur J Endocrinol , vol.137 , pp. 675-683
    • Schöfl, C.1    Becker, C.2    Prank, K.3
  • 139
    • 0033128888 scopus 로고    scopus 로고
    • Lack of leptin suppression in response to hypersecretion of catecholamines in pheochromocytoma patients
    • 139. Böttner A, Eisenhofer G, Torpy DJ, et al. Lack of leptin suppression in response to hypersecretion of catecholamines in pheochromocytoma patients. Metabolism 1999; 48: 543-545.
    • (1999) Metabolism , vol.48 , pp. 543-545
    • Böttner, A.1    Eisenhofer, G.2    Torpy, D.J.3
  • 140
    • 0030735541 scopus 로고    scopus 로고
    • Isoproterenol and somatostatin decrease plasma leptin in humans: A novel mechanism regulating leptin secretion
    • 140. Donahoo WT, Jensen DR, Yost TJ, et al. Isoproterenol and somatostatin decrease plasma leptin in humans: a novel mechanism regulating leptin secretion. J Clin Endocrinol Metab 1997; 82: 4139-4143.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 4139-4143
    • Donahoo, W.T.1    Jensen, D.R.2    Yost, T.J.3
  • 141
    • 0031835502 scopus 로고    scopus 로고
    • Effect of isoprenaline on plasma leptin and lipolysis in humans
    • 141. Pinkney JH, Coppack SW Mohamed-Ali V. Effect of isoprenaline on plasma leptin and lipolysis in humans. Clin Endocrinol 1998; 48: 407-411.
    • (1998) Clin Endocrinol , vol.48 , pp. 407-411
    • Pinkney, J.H.1    Coppack, S.W.2    Mohamed-Ali, V.3
  • 142
    • 0033126914 scopus 로고    scopus 로고
    • Isoproterenol decreases leptin expression in adipose tissue of obese humans
    • 142. Ricci MR, Fried SK. Isoproterenol decreases leptin expression in adipose tissue of obese humans. Obesity Res 1999; 7: 233-240.
    • (1999) Obesity Res , vol.7 , pp. 233-240
    • Ricci, M.R.1    Fried, S.K.2
  • 143
    • 4243243299 scopus 로고    scopus 로고
    • Acute cold exposure decreases plasma leptin in women
    • 143. Ricci MR, Fried SK Mittleman KD. Acute cold exposure decreases plasma leptin in women. FASEB J 1999; 13: A750.
    • (1999) FASEB J , vol.13
    • Ricci, M.R.1    Fried, S.K.2    Mittleman, K.D.3
  • 144
    • 0033002267 scopus 로고    scopus 로고
    • The role of the sympathetic nervous system in the regulation of leptin synthesis in C57BL/6 mice
    • 144. Evans BA, Agar L Summers RJ. The role of the sympathetic nervous system in the regulation of leptin synthesis in C57BL/6 mice. FEBS Lett 1999; 444: 149-154.
    • (1999) FEBS Lett , vol.444 , pp. 149-154
    • Evans, B.A.1    Agar, L.2    Summers, R.J.3
  • 145
    • 0029813768 scopus 로고    scopus 로고
    • The β3-adrenergic receptor inhibits insulin-stimulated leptin secretion from isolated rat adipocytes
    • 145. Gettys TW, Harkness PJ Watson PM. The β3-adrenergic receptor inhibits insulin-stimulated leptin secretion from isolated rat adipocytes. Endocrinology 1996; 137: 4054-4057.
    • (1996) Endocrinology , vol.137 , pp. 4054-4057
    • Gettys, T.W.1    Harkness, P.J.2    Watson, P.M.3
  • 146
    • 0028826355 scopus 로고
    • Acute cold-induced suppression of ob (obese) gene expression in white adipose tissue of mice: Mediation by the sympathetic system
    • 146. Trayhurn P, Duncan JS Rayner DV. Acute cold-induced suppression of ob (obese) gene expression in white adipose tissue of mice: mediation by the sympathetic system. Biochem J 1995; 311: 729-733.
    • (1995) Biochem J , vol.311 , pp. 729-733
    • Trayhurn, P.1    Duncan, J.S.2    Rayner, D.V.3
  • 147
    • 0032537508 scopus 로고    scopus 로고
    • Hyperleptinemia in mice induced by administration of the tyrosine hydroxylase inhibitor α-methyl-p-tyrosine
    • 147. Rayner DV, Simón E, Duncan JS, et al. Hyperleptinemia in mice induced by administration of the tyrosine hydroxylase inhibitor α-methyl-p-tyrosine. FEBS Lett 1998; 429: 395-398.
    • (1998) FEBS Lett , vol.429 , pp. 395-398
    • Rayner, D.V.1    Simón, E.2    Duncan, J.S.3
  • 148
    • 0029157428 scopus 로고
    • Transient increase in obese gene expression after food intake or insulin administration
    • 148. Saladin R, De Vos P, Guerre-Millo M, et al. Transient increase in obese gene expression after food intake or insulin administration. Nature 1995; 377: 527-529.
    • (1995) Nature , vol.377 , pp. 527-529
    • Saladin, R.1    De Vos, P.2    Guerre-Millo, M.3
  • 149
    • 0032032575 scopus 로고    scopus 로고
    • Postnatal surge and regulation of arcadian rhythm of leptin by feeding. Implications for energy homeostasis and neuroendocrine function
    • 149. Ahima RS, Prabakaran D Flier JS. Postnatal surge and regulation of arcadian rhythm of leptin by feeding. Implications for energy homeostasis and neuroendocrine function. J Clin Invest 1998; 101: 1020-1027.
    • (1998) J Clin Invest , vol.101 , pp. 1020-1027
    • Ahima, R.S.1    Prabakaran, D.2    Flier, J.S.3
  • 150
    • 0031932728 scopus 로고    scopus 로고
    • Ultradian pulsatility of plasma glucose and insulin secretion rate: Circadian and sleep modulation
    • 150. Simon C. Ultradian pulsatility of plasma glucose and insulin secretion rate: circadian and sleep modulation. Horm Res 1998; 49: 185-190.
    • (1998) Horm Res , vol.49 , pp. 185-190
    • Simon, C.1
  • 151
    • 0026757643 scopus 로고
    • Low-and high-frequency insulin secretion pulses in pancreas transplant recipients: Role of extrinsic innervation
    • 151. Sonnenberg GE, Hoffmann RG, Johnson CP, et al. Low-and high-frequency insulin secretion pulses in pancreas transplant recipients: role of extrinsic innervation. J Clin Invest 1992; 90: 545-553.
    • (1992) J Clin Invest , vol.90 , pp. 545-553
    • Sonnenberg, G.E.1    Hoffmann, R.G.2    Johnson, C.P.3
  • 152
    • 0025608794 scopus 로고
    • Sustained oscillatory insulin secretion after pancreas transplantation
    • 152. Kern W, Born J, Fehm HL, et al. Sustained oscillatory insulin secretion after pancreas transplantation. Horm Metab Res 1990; 22: 644-646.
    • (1990) Horm Metab Res , vol.22 , pp. 644-646
    • Kern, W.1    Born, J.2    Fehm, H.L.3
  • 153
    • 15844409555 scopus 로고    scopus 로고
    • Role of leptin in fat regulation
    • 153. Collins S, Kuhn CM, Petro AE, et al. Role of leptin in fat regulation. Nature 1996; 380: 677.
    • (1996) Nature , vol.380 , pp. 677
    • Collins, S.1    Kuhn, C.M.2    Petro, A.E.3
  • 154
    • 0032893256 scopus 로고    scopus 로고
    • Induction of uncoupling protein expression in brown and white adipose tissue by leptin
    • 154. Commins SP, Watson PM, Padgett MA, et al. Induction of uncoupling protein expression in brown and white adipose tissue by leptin. Endocrinology 1999; 140: 292-300.
    • (1999) Endocrinology , vol.140 , pp. 292-300
    • Commins, S.P.1    Watson, P.M.2    Padgett, M.A.3
  • 155
    • 0031748933 scopus 로고    scopus 로고
    • Chronic central leptin infusion enhances insulin-stimulated glucose metabolism and favors the expression of uncoupling proteins
    • 155. Cusin I, Zakrewska KE, Boss O, et al. Chronic central leptin infusion enhances insulin-stimulated glucose metabolism and favors the expression of uncoupling proteins. Diabetes 1998; 47: 1014-1019.
    • (1998) Diabetes , vol.47 , pp. 1014-1019
    • Cusin, I.1    Zakrewska, K.E.2    Boss, O.3
  • 156
    • 0032547042 scopus 로고    scopus 로고
    • Satiety effect and sympathetic activation of leptin are mediated by hypothalamic melanocortin system
    • 156. Satoh N, Ogawa Y, Katsuura G, et al. Satiety effect and sympathetic activation of leptin are mediated by hypothalamic melanocortin system. Neurosci Lett 1998; 249: 107-110.
    • (1998) Neurosci Lett , vol.249 , pp. 107-110
    • Satoh, N.1    Ogawa, Y.2    Katsuura, G.3
  • 157
    • 0031821693 scopus 로고    scopus 로고
    • Leptin induction of UCP1 gene expression is dependent on sympathetic innervation
    • 157. Scarpace PJ, Matheny M. Leptin induction of UCP1 gene expression is dependent on sympathetic innervation. Am J Physiol 1998; 275: E259-E264.
    • (1998) Am J Physiol , vol.275
    • Scarpace, P.J.1    Matheny, M.2
  • 158
    • 0030847432 scopus 로고    scopus 로고
    • Acute stimulation of glucose metabolism in mice by leptin treatment
    • 158. Kamohara S, Burcelin R, Halaas JL, et al. Acute stimulation of glucose metabolism in mice by leptin treatment. Nature 1997; 389: 374-377.
    • (1997) Nature , vol.389 , pp. 374-377
    • Kamohara, S.1    Burcelin, R.2    Halaas, J.L.3
  • 159
    • 0032971214 scopus 로고    scopus 로고
    • Microinjection of leptin in the ventromedial hypothalamus increases glucose uptake in peripheral tissues in rats
    • 159. Minokoshi Y, Haque MS Shimazu T. Microinjection of leptin in the ventromedial hypothalamus increases glucose uptake in peripheral tissues in rats. Diabetes 1999; 48: 287-291.
    • (1999) Diabetes , vol.48 , pp. 287-291
    • Minokoshi, Y.1    Haque, M.S.2    Shimazu, T.3
  • 160
    • 0030755270 scopus 로고    scopus 로고
    • Morphologic and molecular changes induced by recombinant human leptin in the white and brown adipose tissues of C57BL/6 mice
    • 160. Sarmiento U, Benson B, Kaufman S, et al. Morphologic and molecular changes induced by recombinant human leptin in the white and brown adipose tissues of C57BL/6 mice. Lab Invest 1997; 77: 243-256.
    • (1997) Lab Invest , vol.77 , pp. 243-256
    • Sarmiento, U.1    Benson, B.2    Kaufman, S.3
  • 161
    • 0031467631 scopus 로고    scopus 로고
    • Direct effects of leptin on brown and white adipose tissues
    • 161. Siegrist-Kaiser CA, Pauli V, Juge-Aubry CE, et al. Direct effects of leptin on brown and white adipose tissues. J Clin Invest 1997; 100: 2858-2864.
    • (1997) J Clin Invest , vol.100 , pp. 2858-2864
    • Siegrist-Kaiser, C.A.1    Pauli, V.2    Juge-Aubry, C.E.3
  • 162
    • 0030876805 scopus 로고    scopus 로고
    • Receptor-mediated regional sympathetic nerve activation by leptin
    • 162. Haynes WG, Morgan DA, Walsh SA, et al. Receptor-mediated regional sympathetic nerve activation by leptin. J Clin Invest 1997; 107: 270-278.
    • (1997) J Clin Invest , vol.107 , pp. 270-278
    • Haynes, W.G.1    Morgan, D.A.2    Walsh, S.A.3
  • 163
    • 0030847881 scopus 로고    scopus 로고
    • Sympathetic and cardiorenal actions of leptin
    • 163. Haynes WG, Sivitz WI, Morgan DA, et al. Sympathetic and cardiorenal actions of leptin. Hypertension 1997; 30: 619-623.
    • (1997) Hypertension , vol.30 , pp. 619-623
    • Haynes, W.G.1    Sivitz, W.I.2    Morgan, D.A.3
  • 164
    • 0031884693 scopus 로고    scopus 로고
    • Cardiovascular consequences of obesity: Role of leptin
    • 164. Haynes WG. Cardiovascular consequences of obesity: role of leptin. Clin Exp Pharmacol Physiol 1998; 25: 65-69.
    • (1998) Clin Exp Pharmacol Physiol , vol.25 , pp. 65-69
    • Haynes, W.G.1
  • 165
    • 0032899719 scopus 로고    scopus 로고
    • Interactions between the melanocortin system and leptin in control of sympathetic nerve traffic
    • 165. Haynes WG, Morgan DA, Djalali A, et al. Interactions between the melanocortin system and leptin in control of sympathetic nerve traffic. Hypertension 1999; 33(Part II): 542-547.
    • (1999) Hypertension , vol.33 , Issue.PART II , pp. 542-547
    • Haynes, W.G.1    Morgan, D.A.2    Djalali, A.3
  • 166
    • 0033051923 scopus 로고    scopus 로고
    • Central administration of leptin inhibits food intake and activates the sympathetic nervous system in rhesus macaques
    • 166. Tang-Christensen M, Havel PJ, Jacobs RR, et al. Central administration of leptin inhibits food intake and activates the sympathetic nervous system in rhesus macaques. J Clin Endocrinol Metab 1999; 84: 711-717.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 711-717
    • Tang-Christensen, M.1    Havel, P.J.2    Jacobs, R.R.3
  • 167
    • 0031765344 scopus 로고    scopus 로고
    • Innervation of mammalian white adipose tissue: Implications for the regulation of total body fat
    • 167. Bartness TJ, Bamshad M. Innervation of mammalian white adipose tissue: implications for the regulation of total body fat. Am J Physiol 1998; 275: R1399-R1411.
    • (1998) Am J Physiol , vol.275
    • Bartness, T.J.1    Bamshad, M.2
  • 168
    • 0031843809 scopus 로고    scopus 로고
    • Central nervous system origins of the sympathetic nervous system outflow to white adipose tissue
    • 168. Bamshad M, Aoki VT, Adkison MG, et al. Central nervous system origins of the sympathetic nervous system outflow to white adipose tissue. Am J Physiol 1998; 275: R291-R299.
    • (1998) Am J Physiol , vol.275
    • Bamshad, M.1    Aoki, V.T.2    Adkison, M.G.3
  • 169
    • 0031711172 scopus 로고    scopus 로고
    • Sensory nerves affect the recruitment and differentiation of rat periovarian brown adipocytes during cold acclimation
    • 169. Giordano A, Morroni M, Carle F, et al. Sensory nerves affect the recruitment and differentiation of rat periovarian brown adipocytes during cold acclimation. J Cell Sci 1998; 111: 2587-2594.
    • (1998) J Cell Sci , vol.111 , pp. 2587-2594
    • Giordano, A.1    Morroni, M.2    Carle, F.3
  • 170
    • 0027443368 scopus 로고
    • Local sympathetic denervation of white adipose tissue in rats induces preadipocyte proliferation without noticeable changes in metabolism
    • 170. Cousin B, Casteilla L, Lafontan M, et al. Local sympathetic denervation of white adipose tissue in rats induces preadipocyte proliferation without noticeable changes in metabolism. Endocrinology 1993; 133: 2255-2262.
    • (1993) Endocrinology , vol.133 , pp. 2255-2262
    • Cousin, B.1    Casteilla, L.2    Lafontan, M.3
  • 171
    • 0031792072 scopus 로고    scopus 로고
    • White adipose tissue sympathetic nervous system denervation increases fat pad mass and fat cell number
    • 171. Youngstrom TG, Bartness TJ. White adipose tissue sympathetic nervous system denervation increases fat pad mass and fat cell number. Am J Physiol 1998; 275: R1488-R1493.
    • (1998) Am J Physiol , vol.275
    • Youngstrom, T.G.1    Bartness, T.J.2
  • 172
    • 0030988937 scopus 로고    scopus 로고
    • Increased sympathetic activity in rat white adipose tissue during prolonged fasting
    • 172. Migliorini RH, Garofalo MAR Kettelhut IC. Increased sympathetic activity in rat white adipose tissue during prolonged fasting. Am J Physiol 1997; 272: R656-R661.
    • (1997) Am J Physiol , vol.272
    • Migliorini, R.H.1    Garofalo, M.A.R.2    Kettelhut, I.C.3
  • 173
    • 0030581526 scopus 로고    scopus 로고
    • Effect of acute cold exposure on norepinephrine turnover rates in rat white adipose tissue
    • 173. Garofalo MAR, Kettelhut IC, Roselino JES, et al. Effect of acute cold exposure on norepinephrine turnover rates in rat white adipose tissue. J Autonom Nerv Syst 1996; 60: 206-208.
    • (1996) J Autonom Nerv Syst , vol.60 , pp. 206-208
    • Garofalo, M.A.R.1    Kettelhut, I.C.2    Roselino, J.E.S.3
  • 174
    • 0031014348 scopus 로고    scopus 로고
    • Effect of fasting, refeeding, and dietary fat restriction on plasma leptin levels
    • 174. Weigle DS, Duell PB, Connor WE, et al. Effect of fasting, refeeding, and dietary fat restriction on plasma leptin levels. J Clin Endocrinol Metab 1997; 82: 561-565.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 561-565
    • Weigle, D.S.1    Duell, P.B.2    Connor, W.E.3
  • 175
    • 0029844267 scopus 로고    scopus 로고
    • Effect of fasting on serum leptin in normal human subjects
    • 175. Boden G, Chen X, Mozzoli M, et al. Effect of fasting on serum leptin in normal human subjects. J Clin Endocrinol Metab 1996; 81: 3419-3423.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 3419-3423
    • Boden, G.1    Chen, X.2    Mozzoli, M.3
  • 176
    • 0029964871 scopus 로고    scopus 로고
    • Responses of leptin to short-term fasting and refeeding in humans
    • 176. Kolaczynski JW, Considine RV, Ohannesian J, et al. Responses of leptin to short-term fasting and refeeding in humans. Diabetes 1996; 45: 1511-1515.
    • (1996) Diabetes , vol.45 , pp. 1511-1515
    • Kolaczynski, J.W.1    Considine, R.V.2    Ohannesian, J.3
  • 177
    • 0030735128 scopus 로고    scopus 로고
    • Effects of fasting and glucose infusion on basal and overnight leptin concentrations in normal-weight women
    • 177. Grinspoon SK, Askari H, Landt ML, et al. Effects of fasting and glucose infusion on basal and overnight leptin concentrations in normal-weight women. Am J Clin Nutr 1997; 66: 1352-1356.
    • (1997) Am J Clin Nutr , vol.66 , pp. 1352-1356
    • Grinspoon, S.K.1    Askari, H.2    Landt, M.L.3
  • 178
    • 0020688573 scopus 로고
    • Sympathetic nervous system activity during exercise
    • 178. Christensen NJ, Galbo H. Sympathetic nervous system activity during exercise. Annu Rev Physiol 1983; 45: 139-153.
    • (1983) Annu Rev Physiol , vol.45 , pp. 139-153
    • Christensen, N.J.1    Galbo, H.2
  • 179
    • 0029864416 scopus 로고    scopus 로고
    • Leptin enters the brain by a saturable system independent of insulin
    • 179. Banks WA, Kastin AJ, Huang W, et al. Leptin enters the brain by a saturable system independent of insulin. Peptides 1996; 17: 305-311.
    • (1996) Peptides , vol.17 , pp. 305-311
    • Banks, W.A.1    Kastin, A.J.2    Huang, W.3
  • 180
    • 0030594830 scopus 로고    scopus 로고
    • Decreased cerebrospinal-fluid/serum leptin ratio in obesity: A possible mechanism for leptin resistance
    • 180. Caro JF, Kolaczynski JW, Nyce MR, et al. Decreased cerebrospinal-fluid/serum leptin ratio in obesity: a possible mechanism for leptin resistance. Lancet 1996; 348: 159-161.
    • (1996) Lancet , vol.348 , pp. 159-161
    • Caro, J.F.1    Kolaczynski, J.W.2    Nyce, M.R.3
  • 181
    • 0343035621 scopus 로고    scopus 로고
    • Relation of leptin and neuropeptide Y in human blood and cerebrospinal fluid
    • 181. Dötsch J, Adelmann M, Englaro P, et al. Relation of leptin and neuropeptide Y in human blood and cerebrospinal fluid. J Neurol Sci 1997; 151: 185-188.
    • (1997) J Neurol Sci , vol.151 , pp. 185-188
    • Dötsch, J.1    Adelmann, M.2    Englaro, P.3
  • 182
    • 0031796971 scopus 로고    scopus 로고
    • Circulating leptin has saturable transport into intrathecal space in humans
    • 182. Koistinen HA, Karonen S-L, livanainen M, et al. Circulating leptin has saturable transport into intrathecal space in humans. Eur J Clin Invest 1998; 28: 894-897.
    • (1998) Eur J Clin Invest , vol.28 , pp. 894-897
    • Koistinen, H.A.1    Karonen, S.-L.2    Livanainen, M.3
  • 183
    • 0031154102 scopus 로고    scopus 로고
    • Cerebrospinal fluid leptin in anorexia nervosa correlation with nutritional status and potential role in resistance to weight gain
    • 183. Mantzoros CS, Flier JS, Lesem MD, et al. Cerebrospinal fluid leptin in anorexia nervosa correlation with nutritional status and potential role in resistance to weight gain. J Clin Endocrinol Metab 1997; 82: 1845-1851.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 1845-1851
    • Mantzoros, C.S.1    Flier, J.S.2    Lesem, M.D.3
  • 184
    • 0029881125 scopus 로고    scopus 로고
    • Cerebrospinal fluid leptin levels: Relationship to plasma levels and to adiposity in humans
    • 184. Schwartz MW, Peskind E, Raskind M, et al. Cerebrospinal fluid leptin levels: relationship to plasma levels and to adiposity in humans. Nat Med 1996; 2: 589-593.
    • (1996) Nat Med , vol.2 , pp. 589-593
    • Schwartz, M.W.1    Peskind, E.2    Raskind, M.3
  • 185
    • 0031761385 scopus 로고    scopus 로고
    • Expression of leptin receptor isoforms in rat brain microvessels
    • 185. Bjørbaek C, Elmquist JK, Michl P, et al. Expression of leptin receptor isoforms in rat brain microvessels. Endocrinology 1998; 139: 3485-3491.
    • (1998) Endocrinology , vol.139 , pp. 3485-3491
    • Bjørbaek, C.1    Elmquist, J.K.2    Michl, P.3
  • 186
    • 0030824058 scopus 로고    scopus 로고
    • Two types of leptin-responsive gastric vagal afferent terminals: An in vitro single-unit study in rats
    • 186. Wang YH, Taché Y, Sheibel AB, et al. Two types of leptin-responsive gastric vagal afferent terminals: an in vitro single-unit study in rats. Am J Physiol 1997; 273: R833-R837.
    • (1997) Am J Physiol , vol.273
    • Wang, Y.H.1    Taché, Y.2    Sheibel, A.B.3
  • 187
    • 0032572705 scopus 로고    scopus 로고
    • Afferent signals from leptin sensors in the white adipose tissue of the epididymis, and their reflex effect in the rat
    • 187. Niijima A. Afferent signals from leptin sensors in the white adipose tissue of the epididymis, and their reflex effect in the rat. J Autonom Nerv Sys 1998; 73: 19-25.
    • (1998) J Autonom Nerv Sys , vol.73 , pp. 19-25
    • Niijima, A.1
  • 188
    • 0033525580 scopus 로고    scopus 로고
    • Reflex effects from leptin sensors in the white adipose tissue of the epididymis to the efferent activity of the sympathetic and vagus nerve in the rat
    • 188. Niijima A. Reflex effects from leptin sensors in the white adipose tissue of the epididymis to the efferent activity of the sympathetic and vagus nerve in the rat. Neurosci Lett 1999; 262: 125-128.
    • (1999) Neurosci Lett , vol.262 , pp. 125-128
    • Niijima, A.1
  • 189
    • 0031840497 scopus 로고    scopus 로고
    • From physiology to neuroendocrinology: A reappraisal of risk factors of body weight gain in humans
    • 189. Tataranni PA. From physiology to neuroendocrinology: a reappraisal of risk factors of body weight gain in humans. Diabetes Metab 1998; 23: 108-115.
    • (1998) Diabetes Metab , vol.23 , pp. 108-115
    • Tataranni, P.A.1
  • 190
    • 0018355535 scopus 로고
    • Obesity genes: Beneficial effects in heterozygous mice
    • 190. Coleman DL. Obesity genes: beneficial effects in heterozygous mice. Science 1979; 203: 663-665.
    • (1979) Science , vol.203 , pp. 663-665
    • Coleman, D.L.1
  • 191
    • 0031576403 scopus 로고    scopus 로고
    • The leptin receptor mediates apparent automne regulation of leptin gene expression
    • 191. Zhang Y, Olbort M, Schwarzer K, et al. The leptin receptor mediates apparent automne regulation of leptin gene expression. Biochem Biophys Res Commun 1997; 240: 492-495.
    • (1997) Biochem Biophys Res Commun , vol.240 , pp. 492-495
    • Zhang, Y.1    Olbort, M.2    Schwarzer, K.3
  • 192
    • 0032177037 scopus 로고    scopus 로고
    • Unraveling the central nervous system pathways underlying responses to leptin
    • 192. Elmquist JK, Maratos-Flier E, Saper CB, et al. Unraveling the central nervous system pathways underlying responses to leptin. Nat Neurosci 1998; 1: 445-450.
    • (1998) Nat Neurosci , vol.1 , pp. 445-450
    • Elmquist, J.K.1    Maratos-Flier, E.2    Saper, C.B.3
  • 193
    • 0031623306 scopus 로고    scopus 로고
    • The MONA LISA hypothesis in the time of leptin
    • 193. Bray GA, York DA. The MONA LISA hypothesis in the time of leptin. Rec Progr Horm Res 1998; 53: 95-118.
    • (1998) Rec Progr Horm Res , vol.53 , pp. 95-118
    • Bray, G.A.1    York, D.A.2
  • 194
    • 0032548825 scopus 로고    scopus 로고
    • Obesity and the hypothalamus: Novel peptides for new pathways
    • 194. Flier JS, Maratos-Flier E. Obesity and the hypothalamus: novel peptides for new pathways. Cell 1998; 92: 437-440.
    • (1998) Cell , vol.92 , pp. 437-440
    • Flier, J.S.1    Maratos-Flier, E.2
  • 195
  • 197
    • 0031730278 scopus 로고    scopus 로고
    • Leptin affects pancreatic endocrine functions through the sympathetic nervous system
    • 197. Mizuno A, Murakami T, Otani S, et al. Leptin affects pancreatic endocrine functions through the sympathetic nervous system. Endocrinology 1998; 139: 3863-3870.
    • (1998) Endocrinology , vol.139 , pp. 3863-3870
    • Mizuno, A.1    Murakami, T.2    Otani, S.3
  • 199
    • 0033044994 scopus 로고    scopus 로고
    • Leptin suppression of insulin secretion and gene expression in human pancreatic islets: Implications for the development of adipogenic diabetes mellitus
    • 199. Seufert J, Kieffer TJ, Leech CA, et al. Leptin suppression of insulin secretion and gene expression in human pancreatic islets: implications for the development of adipogenic diabetes mellitus. J Clin Endocrinol Metab 1999; 84: 670-676.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 670-676
    • Seufert, J.1    Kieffer, T.J.2    Leech, C.A.3
  • 200
    • 0033599562 scopus 로고    scopus 로고
    • Effects of acute or prolonged exposure to human leptin on isolated human islet function
    • 200. Lupi R, Marchetti P, Maffei M, et al. Effects of acute or prolonged exposure to human leptin on isolated human islet function. Biochem Biophys Res Commun 1999; 256: 637-641.
    • (1999) Biochem Biophys Res Commun , vol.256 , pp. 637-641
    • Lupi, R.1    Marchetti, P.2    Maffei, M.3
  • 201
    • 0031448784 scopus 로고    scopus 로고
    • Leptin inhibition of insulin secretion from isolated human islets
    • 201. Fehmann HC, Berghöfer P, Brandhorst D, et al. Leptin inhibition of insulin secretion from isolated human islets. Acta Diabetol 1997; 34: 249-252.
    • (1997) Acta Diabetol , vol.34 , pp. 249-252
    • Fehmann, H.C.1    Berghöfer, P.2    Brandhorst, D.3
  • 202
    • 0029860791 scopus 로고    scopus 로고
    • Modulation of insulin activities by leptin
    • 202. Cohen B, Novick D Rubinstein M. Modulation of insulin activities by leptin. Science 1996; 274: 1185-1188
    • (1996) Science , vol.274 , pp. 1185-1188
    • Cohen, B.1    Novick, D.2    Rubinstein, M.3
  • 203
    • 0030920217 scopus 로고    scopus 로고
    • Leptin receptor action in hepatic cells
    • 203. Wang Y, Kuropatwinski KK, White DW, et al. Leptin receptor action in hepatic cells. J Biol Chem 1997; 272: 16216-16223.
    • (1997) J Biol Chem , vol.272 , pp. 16216-16223
    • Wang, Y.1    Kuropatwinski, K.K.2    White, D.W.3
  • 204
    • 0032934279 scopus 로고    scopus 로고
    • Acute effect of leptin on hepatic glycogenolysis and gluconeogenesis in perfused rat liver
    • 204. Nemecz M, Preininger K, Englisch R, et al. Acute effect of leptin on hepatic glycogenolysis and gluconeogenesis in perfused rat liver. Hepatology 1999; 29: 166-172.
    • (1999) Hepatology , vol.29 , pp. 166-172
    • Nemecz, M.1    Preininger, K.2    Englisch, R.3
  • 205
    • 0031831194 scopus 로고    scopus 로고
    • Acute hyperleptinemia does not modify insulin sensitivity in vivo in the rat
    • 205. Widdowson PS, Upton R, Pickavance L, et al. Acute hyperleptinemia does not modify insulin sensitivity in vivo in the rat. Horm Metab Res 1998; 30: 259-262.
    • (1998) Horm Metab Res , vol.30 , pp. 259-262
    • Widdowson, P.S.1    Upton, R.2    Pickavance, L.3
  • 206
    • 0030784253 scopus 로고    scopus 로고
    • Short term effects of leptin on hepatic gluconeogenesis and in vivo insulin action
    • 206. Rossetti L, Massillon D, Barzilai N, et al. Short term effects of leptin on hepatic gluconeogenesis and in vivo insulin action. J Biol Chem 1997; 272: 27758-27763.
    • (1997) J Biol Chem , vol.272 , pp. 27758-27763
    • Rossetti, L.1    Massillon, D.2    Barzilai, N.3
  • 207
    • 0030737573 scopus 로고    scopus 로고
    • Effects of leptin on insulin sensitivity in normal rats
    • 207. Sivitz WI, Walsh SA, Morgan DA, et al. Effects of leptin on insulin sensitivity in normal rats. Endocrinology 1997; 138: 3395-3401.
    • (1997) Endocrinology , vol.138 , pp. 3395-3401
    • Sivitz, W.I.1    Walsh, S.A.2    Morgan, D.A.3
  • 208
    • 0031734449 scopus 로고    scopus 로고
    • Leptin inhibits directly glucocorticoid secretion of normal human and rat adrenal gland
    • 208. Pralong FP, Roduit R, Waeber G, et al. Leptin inhibits directly glucocorticoid secretion of normal human and rat adrenal gland. Endocrinology 1998; 139: 4264-4268.
    • (1998) Endocrinology , vol.139 , pp. 4264-4268
    • Pralong, F.P.1    Roduit, R.2    Waeber, G.3
  • 209
    • 85011486581 scopus 로고    scopus 로고
    • A leptin dose-response study in obese (ob/ob) and lean (+/?) mice
    • 209. Harris RBS, Zhou J, Redmann Jr SM, et al. A leptin dose-response study in obese (ob/ob) and lean (+/?) mice. Endocrinology 1998; 139: 8-19.
    • (1998) Endocrinology , vol.139 , pp. 8-19
    • Harris, R.B.S.1    Zhou, J.2    Redmann S.M., Jr.3
  • 210
    • 0031817698 scopus 로고    scopus 로고
    • Mode of action of OB protein (leptin) on feeding
    • 210. Flynn MC, Scott TR, Pritchard TC, et al. Mode of action of OB protein (leptin) on feeding. Am J Physiol 1998; 275: R174-R179.
    • (1998) Am J Physiol , vol.275
    • Flynn, M.C.1    Scott, T.R.2    Pritchard, T.C.3
  • 211
    • 0032469070 scopus 로고    scopus 로고
    • Evidence for leptin regulation of food intake in humans
    • 211. Larsson H, Elmståhl S, Berglund G, et al. Evidence for leptin regulation of food intake in humans. J Clin Endocrinol Metab 1998; 83: 4382-4385.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 4382-4385
    • Larsson, H.1    Elmståhl, S.2    Berglund, G.3
  • 212
    • 0030908827 scopus 로고    scopus 로고
    • Raising at thermoneutrality prevents obesity and hyperphagia in BAT-ablated transgenic mice
    • 212. Melnyk A, Harper M-E Himms-Hagen J. Raising at thermoneutrality prevents obesity and hyperphagia in BAT-ablated transgenic mice. Am J Physiol 1997; 272: R1088-R1093.
    • (1997) Am J Physiol , vol.272
    • Melnyk, A.1    Harper, M.-E.2    Himms-Hagen, J.3
  • 213
    • 0031958087 scopus 로고    scopus 로고
    • Temperature-dependent feeding: Lack of role for leptin and defect in brown adipose tissue-ablated obese mice
    • 213. Melnyk A, Himms-Hagen J. Temperature-dependent feeding: lack of role for leptin and defect in brown adipose tissue-ablated obese mice. Am J Physiol 1998; 274: R1131-R1135.
    • (1998) Am J Physiol , vol.274
    • Melnyk, A.1    Himms-Hagen, J.2
  • 214
    • 0020063210 scopus 로고
    • Thermogenesis in diabetes-obesity syndromes in mutant mice
    • 214. Coleman DL. Thermogenesis in diabetes-obesity syndromes in mutant mice. Diabetologia 1982; 22: 205-211.
    • (1982) Diabetologia , vol.22 , pp. 205-211
    • Coleman, D.L.1
  • 215
    • 0023322692 scopus 로고
    • The meal pattern of genetically obese (ob/ob) mice
    • 215. Strohmayer AJ, Smith GP. The meal pattern of genetically obese (ob/ob) mice. Appetite 1987; 8: 111-123.
    • (1987) Appetite , vol.8 , pp. 111-123
    • Strohmayer, A.J.1    Smith, G.P.2
  • 216
    • 0022149781 scopus 로고
    • Effect of adrenalectomy and corticosterone replacement on meal patterns of Zucker rats
    • 216. Freedman MR, Castonguay TW Stern JS. Effect of adrenalectomy and corticosterone replacement on meal patterns of Zucker rats. Am J Physiol 1985; 249: R584-R594.
    • (1985) Am J Physiol , vol.249
    • Freedman, M.R.1    Castonguay, T.W.2    Stern, J.S.3
  • 217
    • 0022981525 scopus 로고
    • Daily rhythms of feeding in the genetically obese and lean Zucker rats
    • 217. Alingh Prins A, de Jong-Nagelsmit A, Keijser J, et al. Daily rhythms of feeding in the genetically obese and lean Zucker rats. Physiol Behav 1986; 38: 423-426.
    • (1986) Physiol Behav , vol.38 , pp. 423-426
    • Alingh Prins, A.1    De Jong-Nagelsmit, A.2    Keijser, J.3
  • 218
    • 0031869047 scopus 로고    scopus 로고
    • Chronic administration of OB protein decreases food intake by selectively reducing meal size in male rats
    • 218. Kahler A, Geary N, Eckel LA, et al. Chronic administration of OB protein decreases food intake by selectively reducing meal size in male rats. Am J Physiol 1998; 275: R180-R185.
    • (1998) Am J Physiol , vol.275
    • Kahler, A.1    Geary, N.2    Eckel, L.A.3
  • 219
    • 0031846614 scopus 로고    scopus 로고
    • Chronic administration of OB protein decreases food intake by selectively reducing meal size in female rats
    • 219. Eckel LA, Langhans W, Kahler A, et al. Chronic administration of OB protein decreases food intake by selectively reducing meal size in female rats. Am J Physiol 1998; 275: R186-R193.
    • (1998) Am J Physiol , vol.275
    • Eckel, L.A.1    Langhans, W.2    Kahler, A.3
  • 220
    • 0032427167 scopus 로고    scopus 로고
    • Intracerebroventricular (i.c.v.) administration of mouse leptin in rats: Behavioral specificity and effects on meal patterns
    • 220. Hulsey MG, Lu H, Wang T, et al. Intracerebroventricular (i.c.v.) administration of mouse leptin in rats: behavioral specificity and effects on meal patterns. Physiol Behav 1998; 65: 445-455.
    • (1998) Physiol Behav , vol.65 , pp. 445-455
    • Hulsey, M.G.1    Lu, H.2    Wang, T.3
  • 221
    • 0028878453 scopus 로고
    • Role of brown adipose tissue thermogenesis in control of thermoregulatory feeding in rats: A new hypothesis that links thermostatic and glucostatic hypotheses for control of food intake
    • 221. Himms-Hagen J. Role of brown adipose tissue thermogenesis in control of thermoregulatory feeding in rats: a new hypothesis that links thermostatic and glucostatic hypotheses for control of food intake. Proc Soc Exp Biol Med 1995; 208: 159-169.
    • (1995) Proc Soc Exp Biol Med , vol.208 , pp. 159-169
    • Himms-Hagen, J.1
  • 222
    • 0030813238 scopus 로고    scopus 로고
    • Leptin is a physiologically important regulator of food intake
    • 222. Brunner L, Nick HP, Cumin F, et al. Leptin is a physiologically important regulator of food intake. Int J Obesity 1997; 21: 1152-1160.
    • (1997) Int J Obesity , vol.21 , pp. 1152-1160
    • Brunner, L.1    Nick, H.P.2    Cumin, F.3
  • 223
    • 0022450740 scopus 로고
    • Norepinephrine stimulates activity of brown adipose tissue in rhesus monkeys
    • 223. Swick AG, Kemnitz JW, Houser WD, et al. Norepinephrine stimulates activity of brown adipose tissue in rhesus monkeys. Int J Obesity 1986; 10: 241-244.
    • (1986) Int J Obesity , vol.10 , pp. 241-244
    • Swick, A.G.1    Kemnitz, J.W.2    Houser, W.D.3
  • 224
    • 0032081279 scopus 로고    scopus 로고
    • A selective human beta3 adrenergic receptor agonist increases metabolic rate in rhesus monkeys
    • 224. Fisher MH, Amend AM, Bach TJ, et al. A selective human beta3 adrenergic receptor agonist increases metabolic rate in rhesus monkeys. J Clin Invest 1998; 101: 2387-2393.
    • (1998) J Clin Invest , vol.101 , pp. 2387-2393
    • Fisher, M.H.1    Amend, A.M.2    Bach, T.J.3
  • 225
    • 0029794957 scopus 로고    scopus 로고
    • Response of leptin to short-term and prolonged overfeeding in humans
    • 225. Kolaczynski JW, Ohannesian J, Considine RV, et al. Response of leptin to short-term and prolonged overfeeding in humans. J Clin Endocrinol Metab 1996; 81: 4162-4165.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 4162-4165
    • Kolaczynski, J.W.1    Ohannesian, J.2    Considine, R.V.3
  • 226
    • 0029819643 scopus 로고    scopus 로고
    • Relationship of plasma leptin to plasma insulin and adiposity in normal weight and overweight women: Effects of dietary fat content and sustained weight loss
    • 226. Havel PJ, Kasim-Karakas S, Mueller W, et al. Relationship of plasma leptin to plasma insulin and adiposity in normal weight and overweight women: effects of dietary fat content and sustained weight loss. J Clin Endocrinol Metab 1996; 81: 4406-4413.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 4406-4413
    • Havel, P.J.1    Kasim-Karakas, S.2    Mueller, W.3
  • 227
    • 0031759898 scopus 로고    scopus 로고
    • Decreased leptin levels in normal weight women with hypothalamic amenorrhea: The effects of body composition and nutritional intake
    • 227. Miller KK, Parulekar MS, Schoenfeld E, et al. Decreased leptin levels in normal weight women with hypothalamic amenorrhea: the effects of body composition and nutritional intake. J Endocrinol Metab 1998; 83: 2309-2312.
    • (1998) J Endocrinol Metab , vol.83 , pp. 2309-2312
    • Miller, K.K.1    Parulekar, M.S.2    Schoenfeld, E.3
  • 228
    • 0033031054 scopus 로고    scopus 로고
    • Functional hypothalamic amenorrhoea: A partial and reversible gonadotropin deficiency of nutritional origin
    • 228. Couzinet B, Young J, Brailly S, et al. Functional hypothalamic amenorrhoea: a partial and reversible gonadotropin deficiency of nutritional origin. Clin Endocrinol 1999; 50: 229-235.
    • (1999) Clin Endocrinol , vol.50 , pp. 229-235
    • Couzinet, B.1    Young, J.2    Brailly, S.3
  • 229
    • 0031847439 scopus 로고    scopus 로고
    • Dietary fat type and energy restriction interactively influence plasma leptin concentration in rats
    • 229. Cha MC, Jones PJH. Dietary fat type and energy restriction interactively influence plasma leptin concentration in rats. J Lipid Res 1998; 39: 1655-1660.
    • (1998) J Lipid Res , vol.39 , pp. 1655-1660
    • Cha, M.C.1    Jones, P.J.H.2
  • 230
    • 0002735953 scopus 로고    scopus 로고
    • Weight loss reverses decreased sensitivity to exogenous OB protein (leptin) in diet-induced obese mice
    • 230. Smith FJ, Rivera I, Tenenbaum R, et al. Weight loss reverses decreased sensitivity to exogenous OB protein (leptin) in diet-induced obese mice. Obesity Res 1998; 22(Suppl 3): S41.
    • (1998) Obesity Res , vol.22 , Issue.SUPPL. 3
    • Smith, F.J.1    Rivera, I.2    Tenenbaum, R.3
  • 231
    • 0032215220 scopus 로고    scopus 로고
    • Obesity due to high fat diet decreases the sympathetic nervous and cardiovascular responses to intracerebroventricular leptin in rats
    • 231. Lu H, Duanmu Z, Houck C, et al. Obesity due to high fat diet decreases the sympathetic nervous and cardiovascular responses to intracerebroventricular leptin in rats. Brain Res Bull 1998; 47: 331-335.
    • (1998) Brain Res Bull , vol.47 , pp. 331-335
    • Lu, H.1    Duanmu, Z.2    Houck, C.3
  • 232
    • 0031876226 scopus 로고    scopus 로고
    • Disturbances of the reproductive axis induced by negative energy balance
    • 232. Judd SJ. Disturbances of the reproductive axis induced by negative energy balance. Reprod Fertil Dev 1998; 10: 65-72.
    • (1998) Reprod Fertil Dev , vol.10 , pp. 65-72
    • Judd, S.J.1
  • 233
    • 0032919990 scopus 로고    scopus 로고
    • Leptin's action on the reproductive axis: Perspectives and mechanisms
    • 233. Cunningham MJ, Clifton DK Steiner RA. Leptin's action on the reproductive axis: perspectives and mechanisms. Biol Reprod 1999; 60: 216-222.
    • (1999) Biol Reprod , vol.60 , pp. 216-222
    • Cunningham, M.J.1    Clifton, D.K.2    Steiner, R.A.3
  • 234
    • 20644445189 scopus 로고    scopus 로고
    • Leptin and reproduction
    • 234. Clarke IJ, Henry BA. Leptin and reproduction. Rev Reprod 1999; 4: 48-55.
    • (1999) Rev Reprod , vol.4 , pp. 48-55
    • Clarke, I.J.1    Henry, B.A.2
  • 235
    • 0030735281 scopus 로고    scopus 로고
    • Expression of functional leptin receptors in the human ovary
    • 235. Karlsson C, Lindell K, Svensson E, et al. Expression of functional leptin receptors in the human ovary. J Clin Endocrinol Metab 1997; 82: 4144-4148.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 4144-4148
    • Karlsson, C.1    Lindell, K.2    Svensson, E.3
  • 236
    • 0033055585 scopus 로고    scopus 로고
    • Leptin antagonizes the insulin-like growth factor-I augmentation of steroidogenesis in granulosa and theca cells of the human ovary
    • 236. Agarwal SK, Vogel K, Weitsman SR, et al. Leptin antagonizes the insulin-like growth factor-I augmentation of steroidogenesis in granulosa and theca cells of the human ovary. J Clin Endocrinol Metab 1999; 84: 1072-1076.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 1072-1076
    • Agarwal, S.K.1    Vogel, K.2    Weitsman, S.R.3
  • 237
    • 0033020962 scopus 로고    scopus 로고
    • Leptin modulates the glucocorticoid-induced ovarian steroidogenesis
    • 237. Barkan D, Jia H, Dantes A, et al. Leptin modulates the glucocorticoid-induced ovarian steroidogenesis. Endocrinology 1999; 140: 1731-1738.
    • (1999) Endocrinology , vol.140 , pp. 1731-1738
    • Barkan, D.1    Jia, H.2    Dantes, A.3
  • 238
    • 0031306926 scopus 로고    scopus 로고
    • Oocyte influences on early development: The regulatory proteins leptin and STAT3 are polarized in mouse and human oocytes and differentially distributed within the cells of the preimplantation stage embryo
    • 238. Antczak M, Van Blerkom J. Oocyte influences on early development: the regulatory proteins leptin and STAT3 are polarized in mouse and human oocytes and differentially distributed within the cells of the preimplantation stage embryo. Mol Hum Reprod 1997; 3: 1067-1086.
    • (1997) Mol Hum Reprod , vol.3 , pp. 1067-1086
    • Antczak, M.1    Van Blerkom, J.2
  • 239
    • 0031808989 scopus 로고    scopus 로고
    • Increase in serum leptin concentrations in women undergoing controlled ovarian hyperstimulation for assisted reproduction
    • 239. Strowitzki T, Kellerer M, Capp E, et al. Increase in serum leptin concentrations in women undergoing controlled ovarian hyperstimulation for assisted reproduction. Gynecol Endocrinol 1998; 12: 167-169.
    • (1998) Gynecol Endocrinol , vol.12 , pp. 167-169
    • Strowitzki, T.1    Kellerer, M.2    Capp, E.3
  • 240
    • 0030813619 scopus 로고    scopus 로고
    • Identification of a placental enhancer for the human leptin gene
    • 240. Bi S, Gavrilova O, Gong D-W, et al. Identification of a placental enhancer for the human leptin gene. J Biol Chem 1997; 272: 30583-30588.
    • (1997) J Biol Chem , vol.272 , pp. 30583-30588
    • Bi, S.1    Gavrilova, O.2    Gong, D.-W.3
  • 241
    • 0031590750 scopus 로고    scopus 로고
    • Identification of the human leptin 5′ flanking sequences involved in the trophoblast-specific transcription
    • 241. Ebihara K, Ogawa Y, Isse N, et al. Identification of the human leptin 5′ flanking sequences involved in the trophoblast-specific transcription. Biochem Biophys Res Commun 1997; 241: 658-663.
    • (1997) Biochem Biophys Res Commun , vol.241 , pp. 658-663
    • Ebihara, K.1    Ogawa, Y.2    Isse, N.3
  • 242
    • 0030931045 scopus 로고    scopus 로고
    • Leptin and leptin receptor mRNA and protein expression in the murine fetus and placenta
    • 242. Hoggard N, Hunter L, Duncan JS, et al. Leptin and leptin receptor mRNA and protein expression in the murine fetus and placenta. Proc Natl Acad Sci USA 1997; 94: 11073-11078.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 11073-11078
    • Hoggard, N.1    Hunter, L.2    Duncan, J.S.3
  • 243
    • 0001643697 scopus 로고    scopus 로고
    • The placenta is not the main source of leptin production in the pregnant rat: Gestational profile of leptin in plasma and adipose tissues
    • 243. Kawai M, Yamaguchi M, Murakami T, et al. The placenta is not the main source of leptin production in the pregnant rat: gestational profile of leptin in plasma and adipose tissues. Biochem Biophys Res Commun 1997; 240: 798-802.
    • (1997) Biochem Biophys Res Commun , vol.240 , pp. 798-802
    • Kawai, M.1    Yamaguchi, M.2    Murakami, T.3
  • 244
    • 0032932669 scopus 로고    scopus 로고
    • Postnatal changes of leptin levels in full-term and preterm neonates: Their relation to intrauterine growth, gender and testosterone
    • 244. Ertl T, Funke S, Sárkány I, et al. Postnatal changes of leptin levels in full-term and preterm neonates: their relation to intrauterine growth, gender and testosterone. Biol Neonate 1999; 75: 167-176.
    • (1999) Biol Neonate , vol.75 , pp. 167-176
    • Ertl, T.1    Funke, S.2    Sárkány, I.3
  • 245
    • 3042812816 scopus 로고    scopus 로고
    • Cord blood leptin concentrations in relation to intrauterine growth
    • 245. Varvarigou A, Mantzoros CS Beratis NG. Cord blood leptin concentrations in relation to intrauterine growth. Clin Endocrinol 1999; 50: 177-183.
    • (1999) Clin Endocrinol , vol.50 , pp. 177-183
    • Varvarigou, A.1    Mantzoros, C.S.2    Beratis, N.G.3
  • 246
    • 0033064807 scopus 로고    scopus 로고
    • Cord blood leptin is associated with size at birth and predicts infancy weight gain in humans
    • 246. Ong KKL, Ahmed ML, Sherriff A, et al. Cord blood leptin is associated with size at birth and predicts infancy weight gain in humans. J Clin Endocrinol Metab 1999; 84: 1145-1148.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 1145-1148
    • Ong, K.K.L.1    Ahmed, M.L.2    Sherriff, A.3
  • 247
    • 0032996658 scopus 로고    scopus 로고
    • Genetic and environmental influences on human cord blood leptin concentration
    • 247. Tarquini B, Tarquini R, Perfetto F, et al. Genetic and environmental influences on human cord blood leptin concentration. Pediatrics 1999; 103: 998-1006.
    • (1999) Pediatrics , vol.103 , pp. 998-1006
    • Tarquini, B.1    Tarquini, R.2    Perfetto, F.3
  • 248
    • 0030884355 scopus 로고    scopus 로고
    • Relationship between concentration of serum leptin and fetal growth
    • 248. Harigaya A, Nagashima K, Nako Y, et al. Relationship between concentration of serum leptin and fetal growth. J Clin Endocrinol Metab 1997; 82: 3281-3284.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 3281-3284
    • Harigaya, A.1    Nagashima, K.2    Nako, Y.3
  • 249
    • 0031929876 scopus 로고    scopus 로고
    • Plasma leptin in infants: Relations to birth weight and weight loss
    • 249. Marchini G, Fried G, Östlund E, et al. Plasma leptin in infants: relations to birth weight and weight loss. Pediatrics 1998; 101: 429-432.
    • (1998) Pediatrics , vol.101 , pp. 429-432
    • Marchini, G.1    Fried, G.2    Östlund, E.3
  • 250
    • 0031936219 scopus 로고    scopus 로고
    • Rapid decline of serum leptin levels in healthy neonates after birth
    • 250. Schübring C, Siebler T, Englaro P, et al. Rapid decline of serum leptin levels in healthy neonates after birth. Eur J Pediatr 1998; 157: 263-264.
    • (1998) Eur J Pediatr , vol.157 , pp. 263-264
    • Schübring, C.1    Siebler, T.2    Englaro, P.3
  • 251
    • 0032439745 scopus 로고    scopus 로고
    • Longitudinal analysis of maternal serum leptin during pregnancy, at birth and up to six weeks after birth: Relation to body mass index, skinfolds, sex steroids and umbilical cord blood leptin levels
    • 251. Schübring C, Englaro P, Siebler T, et al. Longitudinal analysis of maternal serum leptin during pregnancy, at birth and up to six weeks after birth: relation to body mass index, skinfolds, sex steroids and umbilical cord blood leptin levels. Horm Res 1998; 50: 276-283.
    • (1998) Horm Res , vol.50 , pp. 276-283
    • Schübring, C.1    Englaro, P.2    Siebler, T.3
  • 252
    • 0032925976 scopus 로고    scopus 로고
    • Dynamic changes in serum leptin concentrations during the fetal and neonatal periods
    • 252. Matsuda J, Yokota I, Iida M, et al. Dynamic changes in serum leptin concentrations during the fetal and neonatal periods. Pediatr Res 1999; 45: 71-75.
    • (1999) Pediatr Res , vol.45 , pp. 71-75
    • Matsuda, J.1    Yokota, I.2    Iida, M.3
  • 253
    • 0029331734 scopus 로고
    • Does thermoregulatory feeding occur in newborn infants? A novel view of the role of brown adipose tissue thermogenesis in control of food intake
    • 253. Himms-Hagen J. Does thermoregulatory feeding occur in newborn infants? A novel view of the role of brown adipose tissue thermogenesis in control of food intake. Obesity Res 1995; 3: 361-369.
    • (1995) Obesity Res , vol.3 , pp. 361-369
    • Himms-Hagen, J.1
  • 254
    • 0031790849 scopus 로고    scopus 로고
    • Ontogeny of leptin in human fetuses and newborns: Effect of intrauterine growth retardation on serum leptin concentrations
    • 254. Jaquet D, Leger J, Levy-Marchal C, et al. Ontogeny of leptin in human fetuses and newborns: effect of intrauterine growth retardation on serum leptin concentrations. J Clin Endocrinol Metab 1998; 83: 1243-1246.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 1243-1246
    • Jaquet, D.1    Leger, J.2    Levy-Marchal, C.3
  • 255
    • 0030923377 scopus 로고    scopus 로고
    • Effect of birth weight and maternal smoking on cord blood leptin concentrations of full-term and preterm newborns
    • 255. Mantzoros CS, Varvarigou A, Kaklamani VG, et al. Effect of birth weight and maternal smoking on cord blood leptin concentrations of full-term and preterm newborns. J Clin Endocrinol Metab 1997; 82: 2856-2861.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 2856-2861
    • Mantzoros, C.S.1    Varvarigou, A.2    Kaklamani, V.G.3
  • 256
    • 0032891210 scopus 로고    scopus 로고
    • Leptin values in placental cord blood of human newborns with normal intrauterine growth after 30-42 weeks of gestation
    • 256. Gomez L, Carrascosa A, Yeste D, et al. Leptin values in placental cord blood of human newborns with normal intrauterine growth after 30-42 weeks of gestation. Horm Res 1999; 51: 10-14.
    • (1999) Horm Res , vol.51 , pp. 10-14
    • Gomez, L.1    Carrascosa, A.2    Yeste, D.3
  • 257
    • 0030943487 scopus 로고    scopus 로고
    • Serum leptin concentration in cord blood: Relationship to birth weight and gender
    • 257. Matsuda J, Yokota I, Iida M, et al. Serum leptin concentration in cord blood: relationship to birth weight and gender. J Clin Endocrinol Metab 1997; 82: 1642-1644.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 1642-1644
    • Matsuda, J.1    Yokota, I.2    Iida, M.3
  • 258
    • 0032211375 scopus 로고    scopus 로고
    • Cord blood leptin reflects fetal fat mass
    • 258. Clapp III JF, Kiess W. Cord blood leptin reflects fetal fat mass. J Soc Gynecol Invest 1998; 5: 300-303.
    • (1998) J Soc Gynecol Invest , vol.5 , pp. 300-303
    • Clapp J.F. III1    Kiess, W.2
  • 259
    • 0031951673 scopus 로고    scopus 로고
    • Neonatal cord blood leptin: Its relationship to birth weight, body mass index, maternal diabetes, and steroids
    • 259. Shekhawat PS, Garland JS, Shivpuri C, et al. Neonatal cord blood leptin: its relationship to birth weight, body mass index, maternal diabetes, and steroids. Pediatr Res 1998; 43: 338-343.
    • (1998) Pediatr Res , vol.43 , pp. 338-343
    • Shekhawat, P.S.1    Garland, J.S.2    Shivpuri, C.3
  • 260
    • 0030844586 scopus 로고    scopus 로고
    • Postnatal development of the ob gene system: Elevated leptin levels in suckling fa/fa rats
    • 260. Rayner DV, Dalgliesh GD, Duncan JS, et al. Postnatal development of the ob gene system: elevated leptin levels in suckling fa/fa rats. Am J Physiol 1997; 273: E446-R450.
    • (1997) Am J Physiol , vol.273
    • Rayner, D.V.1    Dalgliesh, G.D.2    Duncan, J.S.3
  • 261
    • 0031559755 scopus 로고    scopus 로고
    • Developmental changes in ob gene expression and circulating leptin peptide concentrations
    • 261. Devaskar SU, Ollesch C, Rajakumar RA, et al. Developmental changes in ob gene expression and circulating leptin peptide concentrations. Biochem Biophys Res Commun 1997; 238: 44-47.
    • (1997) Biochem Biophys Res Commun , vol.238 , pp. 44-47
    • Devaskar, S.U.1    Ollesch, C.2    Rajakumar, R.A.3
  • 262
    • 0030944542 scopus 로고    scopus 로고
    • Leptin gene is expressed in rat brown adipose tissue at birth
    • 262. Dessolin S, Schalling M, Champigny O, et al. Leptin gene is expressed in rat brown adipose tissue at birth. FASEB J 1997; 11: 382-387.
    • (1997) FASEB J , vol.11 , pp. 382-387
    • Dessolin, S.1    Schalling, M.2    Champigny, O.3
  • 263
    • 0030447492 scopus 로고    scopus 로고
    • Transient postweaning expression of excessive fat deposition and diabetes mellitus in ob/ob mice
    • 263. Dubuc PU. Transient postweaning expression of excessive fat deposition and diabetes mellitus in ob/ob mice. Growth Dev Aging 1996; 60: 145-151.
    • (1996) Growth Dev Aging , vol.60 , pp. 145-151
    • Dubuc, P.U.1
  • 264
    • 0031769587 scopus 로고    scopus 로고
    • Ontogeny of hyperphagia in the Zucker (fa/fa) rat
    • 264. Kowalski TJ, Ster AM Smith GP. Ontogeny of hyperphagia in the Zucker (fa/fa) rat. Am J Physiol 1998; 275: R1106-R1109.
    • (1998) Am J Physiol , vol.275
    • Kowalski, T.J.1    Ster, A.M.2    Smith, G.P.3
  • 265
    • 0031031623 scopus 로고    scopus 로고
    • Leptin in human reproduction: Serum leptin levels in pregnant and lactating women
    • 265. Butte NF, Hopkinson JM Nicolson MA. Leptin in human reproduction: serum leptin levels in pregnant and lactating women. J Clin Endocrinol Metab 1997; 82: 585-589.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 585-589
    • Butte, N.F.1    Hopkinson, J.M.2    Nicolson, M.A.3
  • 266
    • 0031834764 scopus 로고    scopus 로고
    • Longitudinal changes in maternal serum leptin concentrations, body composition, and resting metabolic rate in pregnancy
    • 266. Highman TJ, Friedman JE, Huston LP, et al. Longitudinal changes in maternal serum leptin concentrations, body composition, and resting metabolic rate in pregnancy. Am J Obstet Gynecol 1998; 178: 1010-1015.
    • (1998) Am J Obstet Gynecol , vol.178 , pp. 1010-1015
    • Highman, T.J.1    Friedman, J.E.2    Huston, L.P.3
  • 267
    • 0031885842 scopus 로고    scopus 로고
    • Leptin levels in pregnancy: Marker for fat accumulation and mobilization?
    • 267. Sattar N, Greer IA, Pirwani I, et al. Leptin levels in pregnancy: marker for fat accumulation and mobilization? Acta Obstet Gynecol Scand 1998; 77: 278-283.
    • (1998) Acta Obstet Gynecol Scand , vol.77 , pp. 278-283
    • Sattar, N.1    Greer, I.A.2    Pirwani, I.3
  • 268
    • 0032937889 scopus 로고    scopus 로고
    • Free leptin, bound leptin, and soluble leptin receptor in normal and diabetic pregnancies
    • 268. Lewandowski K, Horn R, O'Callaghan CJ, et al. Free leptin, bound leptin, and soluble leptin receptor in normal and diabetic pregnancies. J Clin Endocrinol Metab 1999; 84: 300-306.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 300-306
    • Lewandowski, K.1    Horn, R.2    O'Callaghan, C.J.3
  • 269
    • 0031454894 scopus 로고    scopus 로고
    • Sex-based differences in serum leptin concentrations from umbilical cord blood at delivery
    • 269. Tomé MA, Lage M, Camiña J P, et al. Sex-based differences in serum leptin concentrations from umbilical cord blood at delivery. Eur J Endocrinol 1997; 137: 655-658.
    • (1997) Eur J Endocrinol , vol.137 , pp. 655-658
    • Tomé, M.A.1    Lage, M.2    Camiña, J.P.3
  • 270
    • 0032583592 scopus 로고    scopus 로고
    • Serum leptin levels do not rise during pregnancy in age-matched rats
    • 270. Terada Y, Yamakawa K, Sugaya A, et al. Serum leptin levels do not rise during pregnancy in age-matched rats. Biochem Biophys Res Commun 1998; 253: 841-844.
    • (1998) Biochem Biophys Res Commun , vol.253 , pp. 841-844
    • Terada, Y.1    Yamakawa, K.2    Sugaya, A.3
  • 271
    • 0030865242 scopus 로고    scopus 로고
    • The reproductive side of leptin
    • 271. Chehab FF. The reproductive side of leptin. Nat Med 1997; 3: 952-953.
    • (1997) Nat Med , vol.3 , pp. 952-953
    • Chehab, F.F.1
  • 273
    • 0031735478 scopus 로고    scopus 로고
    • Leptin and the onset of puberty
    • 273. Edmonds DK. Leptin and the onset of puberty. Curr Opin Obstet Gynecol 1998; 10: 361-363.
    • (1998) Curr Opin Obstet Gynecol , vol.10 , pp. 361-363
    • Edmonds, D.K.1
  • 274
    • 0031600454 scopus 로고    scopus 로고
    • Leptin, puberty and reproductive function: Lessons from animal studies and human observations
    • 274. Kiess W, Blum WF Aubert ML. Leptin, puberty and reproductive function: lessons from animal studies and human observations. Eur J Endocrinol 1998; 138: 26-29.
    • (1998) Eur J Endocrinol , vol.138 , pp. 26-29
    • Kiess, W.1    Blum, W.F.2    Aubert, M.L.3
  • 275
    • 0032512295 scopus 로고    scopus 로고
    • Uncoupling proteins: The unraveling of obesity?
    • 275. Berger A, Brand M O'Rahilly S. Uncoupling proteins: the unraveling of obesity? Br Med J 1998; 317: 1607-1608.
    • (1998) Br Med J , vol.317 , pp. 1607-1608
    • Berger, A.1    Brand, M.2    O'Rahilly, S.3
  • 276
    • 0032988738 scopus 로고    scopus 로고
    • Longitudinal study of leptin concentrations during puberty: Sex differences and relationship to changes in body composition
    • 276. Ahmed ML, Ong KKL, Morell DJ, et al. Longitudinal study of leptin concentrations during puberty: sex differences and relationship to changes in body composition. J Clin Endocrinol Metab 1999; 84: 899-905.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 899-905
    • Ahmed, M.L.1    Ong, K.K.L.2    Morell, D.J.3
  • 277
    • 0031764501 scopus 로고    scopus 로고
    • Editorial: Leptin and puberty
    • 277. Rogol AD. Editorial: leptin and puberty. J Clin Endocrinol Metab 1998; 83: 1089-1090.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 1089-1090
    • Rogol, A.D.1
  • 278
    • 0030980198 scopus 로고    scopus 로고
    • A longitudinal assessment of hormone and physical alterations during normal puberty in boys. V. Rising leptin levels may signal the onset of puberty
    • 278. Mantzoros CS, Flier JS Rogol AD. A longitudinal assessment of hormone and physical alterations during normal puberty in boys. V. Rising leptin levels may signal the onset of puberty. J Endocrinol Metab 1997; 82: 1066-1070.
    • (1997) J Endocrinol Metab , vol.82 , pp. 1066-1070
    • Mantzoros, C.S.1    Flier, J.S.2    Rogol, A.D.3
  • 280
    • 0031079738 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is the major angiogenic factor in omentum: Mechanism of the omentum-mediated angiogenesis
    • 280. Zhang QX, Magovern CJ, Mack CA, et al. Vascular endothelial growth factor is the major angiogenic factor in omentum: mechanism of the omentum-mediated angiogenesis. J Surg Res 1997; 67: 147-154.
    • (1997) J Surg Res , vol.67 , pp. 147-154
    • Zhang, Q.X.1    Magovern, C.J.2    Mack, C.A.3
  • 281
    • 0032508682 scopus 로고    scopus 로고
    • Biological action of leptin as an angiogenic factor
    • 281. Sierra-Honigmann M, Nath AK, Murakami C, et al. Biological action of leptin as an angiogenic factor. Science 1998; 281: 1683-1686.
    • (1998) Science , vol.281 , pp. 1683-1686
    • Sierra-Honigmann, M.1    Nath, A.K.2    Murakami, C.3
  • 282
    • 0032538875 scopus 로고    scopus 로고
    • Leptin, the product of Ob gene, promotes angiogenesis
    • 282. Bouloumié A, Drexler HCA, Lafontan M, et al. Leptin, the product of Ob gene, promotes angiogenesis. Circ Res 1998; 83: 1059-1066.
    • (1998) Circ Res , vol.83 , pp. 1059-1066
    • Bouloumié, A.1    Drexler, H.C.A.2    Lafontan, M.3
  • 283
    • 0031158830 scopus 로고    scopus 로고
    • A review of the microcirculation of adipose tissue: Anatomic, metabolic, and angiogenic perspectives
    • 283. Crandall DL, Hausman GJ Kral JG. A review of the microcirculation of adipose tissue: anatomic, metabolic, and angiogenic perspectives. Microcirculation 1997; 4: 211-232.
    • (1997) Microcirculation , vol.4 , pp. 211-232
    • Crandall, D.L.1    Hausman, G.J.2    Kral, J.G.3
  • 284
    • 0018861450 scopus 로고
    • Cell-mediated immunity in genetically obese (C57BL/6J ob/ob) mice
    • 284. Chandra RK. Cell-mediated immunity in genetically obese (C57BL/6J ob/ob) mice. Am J Clin Nutr 1980; 33: 13-16.
    • (1980) Am J Clin Nutr , vol.33 , pp. 13-16
    • Chandra, R.K.1
  • 285
    • 0017887735 scopus 로고
    • Immune response in the mutant diabetic C57BL/Ks-db+ mouse
    • 285. Fernandes G, Handwerger BS, Yunis EJ, et al. Immune response in the mutant diabetic C57BL/Ks-db+ mouse. J Clin Invest 1978; 61: 243-250.
    • (1978) J Clin Invest , vol.61 , pp. 243-250
    • Fernandes, G.1    Handwerger, B.S.2    Yunis, E.J.3
  • 286
    • 0028199651 scopus 로고
    • The influence of obesity and its treatment on the immune system
    • 286. Stallone DD. The influence of obesity and its treatment on the immune system. Nutr Rev 1994; 52: 37-50.
    • (1994) Nutr Rev , vol.52 , pp. 37-50
    • Stallone, D.D.1
  • 287
    • 0009912839 scopus 로고    scopus 로고
    • Phenotypic abnormalities in macrophages from leptin-deficient, obese mice
    • 287. Lee F-YJ, Li Y, Yang EK, et al. Phenotypic abnormalities in macrophages from leptin-deficient, obese mice. Am J Physiol 1999; 276: C386-C394.
    • (1999) Am J Physiol , vol.276
    • Lee, F.-Y.J.1    Li, Y.2    Yang, E.K.3
  • 288
    • 0032572722 scopus 로고    scopus 로고
    • Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression
    • 288. Lord GM, Matarese G, Howard JK, et al. Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression. Nature 1998; 394: 897-901.
    • (1998) Nature , vol.394 , pp. 897-901
    • Lord, G.M.1    Matarese, G.2    Howard, J.K.3
  • 289
    • 0030250892 scopus 로고    scopus 로고
    • A role for leptin and its cognate receptor in hematopoiesis
    • 289. Bennett BD, Solar GP, Yuan JQ, et al. A role for leptin and its cognate receptor in hematopoiesis. Curr Biol 1996; 6: 1170-1180.
    • (1996) Curr Biol , vol.6 , pp. 1170-1180
    • Bennett, B.D.1    Solar, G.P.2    Yuan, J.Q.3
  • 290
    • 0031721269 scopus 로고    scopus 로고
    • Lowered leptin slims immune response
    • 290. Flier JS. Lowered leptin slims immune response. Nat Med 1998; 4: 1124-1125.
    • (1998) Nat Med , vol.4 , pp. 1124-1125
    • Flier, J.S.1
  • 291
    • 0030043899 scopus 로고    scopus 로고
    • Immune-neuro-endocrine interactions: Facts and hypotheses
    • 291. Besedovsky HO, del Rey A. Immune-neuro-endocrine interactions: facts and hypotheses. Endocr Rev 1996; 17: 64-102.
    • (1996) Endocr Rev , vol.17 , pp. 64-102
    • Besedovsky, H.O.1    Del Rey, A.2
  • 292
    • 0030007116 scopus 로고    scopus 로고
    • Novel B219/OB receptor isoforms: Possible role of leptin in hematopoiesis and reproduction
    • 292. Cioffi JA, Shafer AW, Zupanic TJ, et al. Novel B219/OB receptor isoforms: possible role of leptin in hematopoiesis and reproduction. Nat Med 1996; 3: 585-589.
    • (1996) Nat Med , vol.3 , pp. 585-589
    • Cioffi, J.A.1    Shafer, A.W.2    Zupanic, T.J.3
  • 293
    • 0032425963 scopus 로고    scopus 로고
    • Identification of a fetal hematopoietic precursor with B cell, T cell and macrophage potential
    • 293. Lacaud G, Carlsson L Keller G. Identification of a fetal hematopoietic precursor with B cell, T cell and macrophage potential. Immunity 1998; 9: 827-838.
    • (1998) Immunity , vol.9 , pp. 827-838
    • Lacaud, G.1    Carlsson, L.2    Keller, G.3
  • 294
    • 0031253897 scopus 로고    scopus 로고
    • Retraction
    • 294. Snodgrass HR. Retraction. Blood 1997; 90: 2862.
    • (1997) Blood , vol.90 , pp. 2862
    • Snodgrass, H.R.1
  • 295
    • 0031027475 scopus 로고    scopus 로고
    • Leptin stimulates fetal and adult erythroid and myeloid development
    • 295. Mikhail AA, Beck EX, Shafer A, et al. Leptin stimulates fetal and adult erythroid and myeloid development. Blood 1997; 89: 1507-1512. (Retraction in Blood 90: 2862).
    • (1997) Blood , vol.89 , pp. 1507-1512
    • Mikhail, A.A.1    Beck, E.X.2    Shafer, A.3
  • 296
    • 0031027475 scopus 로고    scopus 로고
    • Retraction
    • 295. Mikhail AA, Beck EX, Shafer A, et al. Leptin stimulates fetal and adult erythroid and myeloid development. Blood 1997; 89: 1507-1512. (Retraction in Blood 90: 2862).
    • Blood , vol.90 , pp. 2862
  • 297
    • 0030736770 scopus 로고    scopus 로고
    • Leptin stimulates the proliferation of murine myelocytic and primitive hematopoietic progenitor cells
    • 296. Umemoto Y, Tsuji K, Yang F-C, et al. Leptin stimulates the proliferation of murine myelocytic and primitive hematopoietic progenitor cells. Blood 1997; 90: 3438-3443.
    • (1997) Blood , vol.90 , pp. 3438-3443
    • Umemoto, Y.1    Tsuji, K.2    Yang, F.-C.3
  • 298
    • 0033602850 scopus 로고    scopus 로고
    • Human leptin stimulates proliferation and activation of human circulating monocytes
    • 297. Santos-Alvarez J, Goberna R Sánchez-Margalet V. Human leptin stimulates proliferation and activation of human circulating monocytes. Cell Immunol 1999; 194: 6-11.
    • (1999) Cell Immunol , vol.194 , pp. 6-11
    • Santos-Alvarez, J.1    Goberna, R.2    Sánchez-Margalet, V.3
  • 299
    • 0029952911 scopus 로고    scopus 로고
    • Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells
    • 298. Gainsford T, Willson TA, Metcalf D, et al. Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells. Proc Natl Acad Sci USA 1996; 93: 14564-14568.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 14564-14568
    • Gainsford, T.1    Willson, T.A.2    Metcalf, D.3
  • 300
    • 0031965266 scopus 로고    scopus 로고
    • Leptin regulates proinflammatory immune responses
    • 299. Loffreda S, Yang SQ, Lin HZ, et al. Leptin regulates proinflammatory immune responses. FASEB J 1998; 12: 57-65.
    • (1998) FASEB J , vol.12 , pp. 57-65
    • Loffreda, S.1    Yang, S.Q.2    Lin, H.Z.3
  • 301
    • 0032982438 scopus 로고    scopus 로고
    • Leptin acts on human marrow stromal cells to enhance differentiation to osteoblasts and to inhibit differentiation to adipocytes
    • 300. Thomas T, Gori F, Khosla S, et al. Leptin acts on human marrow stromal cells to enhance differentiation to osteoblasts and to inhibit differentiation to adipocytes. Endocrinology 1999; 140: 1630-1638.
    • (1999) Endocrinology , vol.140 , pp. 1630-1638
    • Thomas, T.1    Gori, F.2    Khosla, S.3
  • 302
    • 0029554434 scopus 로고
    • Increased incidence of nosocomial infections in obese surgical patients
    • 301. Choban PS, Heckler R, Burge JC, et al. Increased incidence of nosocomial infections in obese surgical patients. Am Surg 1995; 61: 1001-1005.
    • (1995) Am Surg , vol.61 , pp. 1001-1005
    • Choban, P.S.1    Heckler, R.2    Burge, J.C.3
  • 303
    • 0029046010 scopus 로고
    • Functional consequences of sustained sleep deprivation in the rat
    • 302. Everson CA. Functional consequences of sustained sleep deprivation in the rat. Behav Brain Res 1995; 69: 43-54.
    • (1995) Behav Brain Res , vol.69 , pp. 43-54
    • Everson, C.A.1
  • 304
    • 0028956906 scopus 로고
    • Pituitary and peripheral thyroid hormone responses to thyrotropin-releasing hormone during sustained sleep deprivation in freely moving rats
    • 303. Everson CA, Reed HL. Pituitary and peripheral thyroid hormone responses to thyrotropin-releasing hormone during sustained sleep deprivation in freely moving rats. Endocrinology 1995; 136: 1426-1434.
    • (1995) Endocrinology , vol.136 , pp. 1426-1434
    • Everson, C.A.1    Reed, H.L.2
  • 305
    • 0029046870 scopus 로고
    • Sleep deprivation in the rat by the disk-over-water method
    • 304. Rechtschaffen A, Bergmann P. Sleep deprivation in the rat by the disk-over-water method. Behav Brain Res 1995; 69: 55-63.
    • (1995) Behav Brain Res , vol.69 , pp. 55-63
    • Rechtschaffen, A.1    Bergmann, P.2
  • 306
    • 0030969418 scopus 로고    scopus 로고
    • Operant control of ambient temperature during sleep deprivation
    • 305. Shaw PJ, Bergmann BM Rechtschaffen A. Operant control of ambient temperature during sleep deprivation. Am J Physiol 1997; 272: R682-R690.
    • (1997) Am J Physiol , vol.272
    • Shaw, P.J.1    Bergmann, B.M.2    Rechtschaffen, A.3
  • 307
    • 0031886417 scopus 로고    scopus 로고
    • Effects of paradoxical sleep deprivation on thermoregulation in the rat
    • 306. Shaw PJ, Bergmann BM Rechtschaffen A. Effects of paradoxical sleep deprivation on thermoregulation in the rat. Sleep 1998; 21: 7-17.
    • (1998) Sleep , vol.21 , pp. 7-17
    • Shaw, P.J.1    Bergmann, B.M.2    Rechtschaffen, A.3
  • 308
    • 0031112902 scopus 로고    scopus 로고
    • Interactions between sleep, other body rhythms, immune responses, and exercise
    • 307. Shephard RJ, Shek PN. Interactions between sleep, other body rhythms, immune responses, and exercise. Can J Appl Physiol 1997; 22: 95-116.
    • (1997) Can J Appl Physiol , vol.22 , pp. 95-116
    • Shephard, R.J.1    Shek, P.N.2
  • 309
    • 0031436568 scopus 로고    scopus 로고
    • Sleep and host defenses: A review
    • 308. Benca RM, Quintans J. Sleep and host defenses: a review. Sleep 1997; 20: 1027-1037.
    • (1997) Sleep , vol.20 , pp. 1027-1037
    • Benca, R.M.1    Quintans, J.2
  • 310
    • 0028267914 scopus 로고
    • Leukocytosis and natural killer cell function parallel neurobehavioral fatigue induced by 64 h of sleep deprivation
    • 309. Dinges DF, Douglas SD, Zaugg L, et al. Leukocytosis and natural killer cell function parallel neurobehavioral fatigue induced by 64 h of sleep deprivation. J Clin Invest 1994; 93: 1930-1939.
    • (1994) J Clin Invest , vol.93 , pp. 1930-1939
    • Dinges, D.F.1    Douglas, S.D.2    Zaugg, L.3
  • 311
    • 0028089778 scopus 로고
    • Partial sleep deprivation reduces natural killer cell activity in humans
    • 310. Irwin M, Mascovich A, Gillin JC, et al. Partial sleep deprivation reduces natural killer cell activity in humans. Psychosom Med 1994; 56: 493-498.
    • (1994) Psychosom Med , vol.56 , pp. 493-498
    • Irwin, M.1    Mascovich, A.2    Gillin, J.C.3
  • 312
    • 0030710239 scopus 로고    scopus 로고
    • Association between increased body mass index and a diagnosis of acute promyelocytic leukemia in patients with acute myeloid leukemia
    • 311. Estey F, Thall P, Kantarjian H, et al. Association between increased body mass index and a diagnosis of acute promyelocytic leukemia in patients with acute myeloid leukemia. Leukemia 1997; 11: 1661-1664.
    • (1997) Leukemia , vol.11 , pp. 1661-1664
    • Estey, F.1    Thall, P.2    Kantarjian, H.3
  • 313
    • 0033104708 scopus 로고    scopus 로고
    • Expression and function of leptin receptors isoforms in myeloid leukemia and myelodysplastic syndromes: Proliferative and anti-apoptotic activities
    • 312. Konopleva M, Mikhail A, Estrov Z, et al. Expression and function of leptin receptors isoforms in myeloid leukemia and myelodysplastic syndromes: proliferative and anti-apoptotic activities. Blood 1999; 93: 1668-1676.
    • (1999) Blood , vol.93 , pp. 1668-1676
    • Konopleva, M.1    Mikhail, A.2    Estrov, Z.3
  • 314
    • 8544258847 scopus 로고    scopus 로고
    • Glucorticoid regulation of leptin synthesis and secretion in humans: Elevated plasma leptin levels in Cushing's syndrome
    • 313. Masuzaki H, Ogawa Y, Hosoda K, el al. Glucorticoid regulation of leptin synthesis and secretion in humans: elevated plasma leptin levels in Cushing's syndrome. J Clin Endocrinol Metab 1997; 82: 2542-2547.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 2542-2547
    • Masuzaki, H.1    Ogawa, Y.2    Hosoda, K.3
  • 315
    • 0031698546 scopus 로고    scopus 로고
    • Leptin expression in adipose tissue from obese humans: Depot-specific regulation by insulin and dexamethasone
    • 314. Russell CD, Petersen RN, Rao SP, et al. Leptin expression in adipose tissue from obese humans: depot-specific regulation by insulin and dexamethasone. Am J Physiol 1998; 275: E507-E515.
    • (1998) Am J Physiol , vol.275
    • Russell, C.D.1    Petersen, R.N.2    Rao, S.P.3
  • 316
    • 0030884983 scopus 로고    scopus 로고
    • Robust leptin secretory responses to dexamethasone in obese subjects
    • 315. Dagogo-Jack S, Selke G, Melson AK, et al. Robust leptin secretory responses to dexamethasone in obese subjects. J Endocrinol Metab 1997; 82: 3230-3233.
    • (1997) J Endocrinol Metab , vol.82 , pp. 3230-3233
    • Dagogo-Jack, S.1    Selke, G.2    Melson, A.K.3
  • 317
    • 0031733387 scopus 로고    scopus 로고
    • Dose-dependent cortisol-induced increases in plasma leptin concentration in healthy humans
    • 316. Newcomer JW, Selke G, Melson AK, et al. Dose-dependent cortisol-induced increases in plasma leptin concentration in healthy humans. Arch Gen Psychiatry 1998; 55: 995-1000.
    • (1998) Arch Gen Psychiatry , vol.55 , pp. 995-1000
    • Newcomer, J.W.1    Selke, G.2    Melson, A.K.3
  • 318
    • 0029848687 scopus 로고    scopus 로고
    • Short-term dexamethasone treatment increases plasma leptin independently of changes in insulin sensitivity in healthy women
    • 317. Larsson H, Ahrén B. Short-term dexamethasone treatment increases plasma leptin independently of changes in insulin sensitivity in healthy women. J Endocrinol Metab 1996; 81: 4428-4432.
    • (1996) J Endocrinol Metab , vol.81 , pp. 4428-4432
    • Larsson, H.1    Ahrén, B.2
  • 319
    • 0030670235 scopus 로고    scopus 로고
    • Dexamethasone, OB gene, and leptin in humans: Effect of exogenous hyperinsulinemia
    • 318. Kolaczynski JW, Goldstein BJ Considine RV. Dexamethasone, OB gene, and leptin in humans: effect of exogenous hyperinsulinemia. J Clin Endocrinol Metab 1997; 82: 3895-3897.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 3895-3897
    • Kolaczynski, J.W.1    Goldstein, B.J.2    Considine, R.V.3
  • 320
    • 0030452084 scopus 로고    scopus 로고
    • Dexamethasone induces an acute and sustained rise in circulating leptin levels in normal human subjects
    • 319. Miell JP, Englaro P Blum WF. Dexamethasone induces an acute and sustained rise in circulating leptin levels in normal human subjects. Horm Metab Res 1996; 28: 704-707.
    • (1996) Horm Metab Res , vol.28 , pp. 704-707
    • Miell, J.P.1    Englaro, P.2    Blum, W.F.3
  • 321
    • 0031762372 scopus 로고    scopus 로고
    • Multihormonal control of ob gene expression and leptin secretion from cultured human visceral adipose tissue: Increased responsiveness to glucocorticoids in obesity
    • 320. Halleux CM, Servais I, Reul BA, et al. Multihormonal control of ob gene expression and leptin secretion from cultured human visceral adipose tissue: increased responsiveness to glucocorticoids in obesity. J Clin Endocrinol Metab 1998; 83: 902-910.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 902-910
    • Halleux, C.M.1    Servais, I.2    Reul, B.A.3
  • 322
    • 0030852568 scopus 로고    scopus 로고
    • Plasma leptin levels do not change in patients with Gushing's disease shortly after correction of hypercortisolism
    • 321. Cizza G, Lotsikas AJ, Licinio J, et al. Plasma leptin levels do not change in patients with Gushing's disease shortly after correction of hypercortisolism. J Clin Endocrinol Metab 1997; 82: 2747-2750.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 2747-2750
    • Cizza, G.1    Lotsikas, A.J.2    Licinio, J.3
  • 323
    • 0030482360 scopus 로고    scopus 로고
    • Hyperleptinemia in chronic renal failure
    • 322. Iida M, Murakami T, Yamada M, et al. Hyperleptinemia in chronic renal failure. Horm Metab Res 1996; 28: 724-727.
    • (1996) Horm Metab Res , vol.28 , pp. 724-727
    • Iida, M.1    Murakami, T.2    Yamada, M.3
  • 324
    • 0031921198 scopus 로고    scopus 로고
    • Plasma leptin level and its relationship with body composition in hemodialysis patients
    • 323. Nishizawa Y, Shoji T, Tanaka S, et al. Plasma leptin level and its relationship with body composition in hemodialysis patients. Am J Kidney Dis 1998; 31: 655-661.
    • (1998) Am J Kidney Dis , vol.31 , pp. 655-661
    • Nishizawa, Y.1    Shoji, T.2    Tanaka, S.3
  • 325
    • 0031017938 scopus 로고    scopus 로고
    • Increased plasma leptin concentration in end-stage renal disease
    • 324. Merabet E, Dagogo-Jack S, Coyne DW, et al. Increased plasma leptin concentration in end-stage renal disease. J Clin Endocrinol Metab 1997; 82: 847-850.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 847-850
    • Merabet, E.1    Dagogo-Jack, S.2    Coyne, D.W.3
  • 326
    • 8244232511 scopus 로고    scopus 로고
    • Plasma leptin is cleared by the kidney and is elevated in hemodialysis patients
    • 325. Sharma K, Considine RV, Michael B, et al. Plasma leptin is cleared by the kidney and is elevated in hemodialysis patients. Kidney Int 1997; 51: 1980-1985.
    • (1997) Kidney Int , vol.51 , pp. 1980-1985
    • Sharma, K.1    Considine, R.V.2    Michael, B.3
  • 327
    • 0031747816 scopus 로고    scopus 로고
    • The OB protein (leptin) and the kidney
    • 326. Sharma K, Considine RV. The OB protein (leptin) and the kidney. Kidney Int 1998; 53: 1483-1487.
    • (1998) Kidney Int , vol.53 , pp. 1483-1487
    • Sharma, K.1    Considine, R.V.2
  • 328
    • 0030818802 scopus 로고    scopus 로고
    • Renal function and insulin resistance as determinants of plasma leptin levels in patients with NIDDM
    • 327. Shoji T, Nishizawa Y, Emoto M, et al. Renal function and insulin resistance as determinants of plasma leptin levels in patients with NIDDM. Diabetologia 1997; 40: 676-679.
    • (1997) Diabetologia , vol.40 , pp. 676-679
    • Shoji, T.1    Nishizawa, Y.2    Emoto, M.3
  • 329
    • 0031778958 scopus 로고    scopus 로고
    • Leptin, body composition, and indices of malnutrition in patients on dialysis
    • 328. Johansen KL, Mulligan K, Tal V, et al. Leptin, body composition, and indices of malnutrition in patients on dialysis. J Am Soc Nephrol 1998; 9: 1080-1084.
    • (1998) J Am Soc Nephrol , vol.9 , pp. 1080-1084
    • Johansen, K.L.1    Mulligan, K.2    Tal, V.3
  • 330
    • 0031954362 scopus 로고    scopus 로고
    • Hyperleptinemia in patients with end-stage renal disease undergoing continuous ambulatory peritoneal dialysis
    • 329. Dagogo-Jack S, Ovalle F, Landt M, et al. Hyperleptinemia in patients with end-stage renal disease undergoing continuous ambulatory peritoneal dialysis. Perit Dial Int 1998; 18: 34-40.
    • (1998) Perit Dial Int , vol.18 , pp. 34-40
    • Dagogo-Jack, S.1    Ovalle, F.2    Landt, M.3
  • 331
    • 0344588820 scopus 로고    scopus 로고
    • Inappropriate elevation of the serum leptin levels in children with chronic renal failure
    • 330. Daschner M, Tönshoff B, Blum WF, et al. Inappropriate elevation of the serum leptin levels in children with chronic renal failure. J Am Soc Nephrol 1998; 9: 1074-1079.
    • (1998) J Am Soc Nephrol , vol.9 , pp. 1074-1079
    • Daschner, M.1    Tönshoff, B.2    Blum, W.F.3
  • 332
    • 0031697047 scopus 로고    scopus 로고
    • Plasma leptin concentration in kidney transplant patients during the early post-transplant period
    • 331. Kokot F, Adamczak M Wiecek A. Plasma leptin concentration in kidney transplant patients during the early post-transplant period. Nephrol Dial Transplant 1998; 13: 2276-2280.
    • (1998) Nephrol Dial Transplant , vol.13 , pp. 2276-2280
    • Kokot, F.1    Adamczak, M.2    Wiecek, A.3
  • 333
    • 0032960449 scopus 로고    scopus 로고
    • Pathophysiological role of leptin in patients with chronic renal failure, in kidney transplant patients, in patients with essential hypertension, and in pregnant women with preeclampsia
    • 332. Kokot F, Wiecek A, Adamczak M, et al. Pathophysiological role of leptin in patients with chronic renal failure, in kidney transplant patients, in patients with essential hypertension, and in pregnant women with preeclampsia. Artif Organs 1999; 23: 70-74.
    • (1999) Artif Organs , vol.23 , pp. 70-74
    • Kokot, F.1    Wiecek, A.2    Adamczak, M.3
  • 334
    • 0033034583 scopus 로고    scopus 로고
    • Plasma immunoreactive leptin and neuropeptide Y levels in kidney transplant patients
    • 333. Kokot F, Adamczak M, Wiecek A, et al. Plasma immunoreactive leptin and neuropeptide Y levels in kidney transplant patients. Am J Nephrol 1999; 19: 28-33.
    • (1999) Am J Nephrol , vol.19 , pp. 28-33
    • Kokot, F.1    Adamczak, M.2    Wiecek, A.3
  • 335
    • 0031960008 scopus 로고    scopus 로고
    • Leptin - A new hormone of definite interest for the nephrologist
    • 334. Stenvinkel P. Leptin - a new hormone of definite interest for the nephrologist. Nephrol Dial Transplant 1998; 13: 1099-1101.
    • (1998) Nephrol Dial Transplant , vol.13 , pp. 1099-1101
    • Stenvinkel, P.1
  • 336
    • 0031955696 scopus 로고    scopus 로고
    • Inappropriately high plasma leptin levels in obese haemodialysis patients can be reduced by high flux haemodialysis and haemodiafiltration
    • 335. Wiesholzer M, Harm F, Hauser A-C, et al. Inappropriately high plasma leptin levels in obese haemodialysis patients can be reduced by high flux haemodialysis and haemodiafiltration. Clin Sci 1998; 94: 431-435.
    • (1998) Clin Sci , vol.94 , pp. 431-435
    • Wiesholzer, M.1    Harm, F.2    Hauser, A.-C.3
  • 337
    • 0031771561 scopus 로고    scopus 로고
    • High-flux dialysis lowers plasma leptin concentration in chronic dialysis patients
    • 336. Coyne DW, Dagogo-Jack S, Klein S, et al. High-flux dialysis lowers plasma leptin concentration in chronic dialysis patients. Am J Kidney Dis 1998; 32: 1031-1035.
    • (1998) Am J Kidney Dis , vol.32 , pp. 1031-1035
    • Coyne, D.W.1    Dagogo-Jack, S.2    Klein, S.3
  • 338
    • 0031671181 scopus 로고    scopus 로고
    • Hyperleptinemia of end-stage renal disease is corrected by renal transplantation
    • 337. Landt M, Brennan DC, Parvin CA, et al. Hyperleptinemia of end-stage renal disease is corrected by renal transplantation. Nephrol Dial Transplant 1998; 13: 2271-2275.
    • (1998) Nephrol Dial Transplant , vol.13 , pp. 2271-2275
    • Landt, M.1    Brennan, D.C.2    Parvin, C.A.3
  • 339
    • 0033004296 scopus 로고    scopus 로고
    • Leptin elimination in hyperleptinaemic peritoneal dialysis patients
    • 338. Landt M, Parvin CA, Dagogo-Jack S, et al. Leptin elimination in hyperleptinaemic peritoneal dialysis patients. Nephrol Dial Transplant 1999; 14: 732-737.
    • (1999) Nephrol Dial Transplant , vol.14 , pp. 732-737
    • Landt, M.1    Parvin, C.A.2    Dagogo-Jack, S.3
  • 340
    • 0033372252 scopus 로고    scopus 로고
    • The effect of continuous ambulatory peritoneal dialysis on change in serum leptin
    • 339. Kim DJ, Oh DJ, Kim B, et al. The effect of continuous ambulatory peritoneal dialysis on change in serum leptin. Perit Dial Int 1999; 19(Suppl 2): S172-S175.
    • (1999) Perit Dial Int , vol.19 , Issue.SUPPL. 2
    • Kim, D.J.1    Oh, D.J.2    Kim, B.3
  • 341
    • 0031719130 scopus 로고    scopus 로고
    • Serum leptin concentrations in patients on hemodialysis
    • 340. Nakazono H, Nagake Y, Ichikawa H, et al. Serum leptin concentrations in patients on hemodialysis. Nephron 1998; 80: 35-40.
    • (1998) Nephron , vol.80 , pp. 35-40
    • Nakazono, H.1    Nagake, Y.2    Ichikawa, H.3
  • 342
    • 0032603521 scopus 로고    scopus 로고
    • Obesity-induced hypertension. New concepts from the emerging biology of obesity
    • 341. Mark AL, Correia M, Morgan DA, et al. Obesity-induced hypertension. New concepts from the emerging biology of obesity. Hypertension 1999; 33(Part II): 537-541.
    • (1999) Hypertension , vol.33 , Issue.PART II , pp. 537-541
    • Mark, A.L.1    Correia, M.2    Morgan, D.A.3
  • 343
    • 0030830662 scopus 로고    scopus 로고
    • Intracerebroventricular leptin increases lumbar and renal sympathetic nerve activity and blood pressure in normal rats
    • 342. Dunbar JC, Hu Y Lu H. Intracerebroventricular leptin increases lumbar and renal sympathetic nerve activity and blood pressure in normal rats. Diabetes 1997; 46: 2040-2043.
    • (1997) Diabetes , vol.46 , pp. 2040-2043
    • Dunbar, J.C.1    Hu, Y.2    Lu, H.3
  • 344
    • 0032540488 scopus 로고    scopus 로고
    • Effects of central leptin administration on blood pressure in normotensive rats
    • 343. Casto RM, VanNess JM Overton JM. Effects of central leptin administration on blood pressure in normotensive rats. Neurosci Lett 1998; 246: 29-32.
    • (1998) Neurosci Lett , vol.246 , pp. 29-32
    • Casto, R.M.1    VanNess, J.M.2    Overton, J.M.3
  • 345
    • 0031606279 scopus 로고    scopus 로고
    • Chronic leptin infusion increases arterial pressure
    • 344. Shek EW, Brands MW Hall JE. Chronic leptin infusion increases arterial pressure. Hypertension 1998; 31: 409-414.
    • (1998) Hypertension , vol.31 , pp. 409-414
    • Shek, E.W.1    Brands, M.W.2    Hall, J.E.3
  • 346
    • 0031052428 scopus 로고    scopus 로고
    • Characterization and localization of leptin receptors in the rat kidney
    • 345. Serradeil-Le Gal C, Raufaste D, Brossard G, et al. Characterization and localization of leptin receptors in the rat kidney. FEBS Lett 1997; 404: 185-191.
    • (1997) FEBS Lett , vol.404 , pp. 185-191
    • Serradeil-Le Gal, C.1    Raufaste, D.2    Brossard, G.3
  • 347
    • 0030771886 scopus 로고    scopus 로고
    • Human leptin has natriuretic activity in the rat
    • 346. Jackson EK, Li P. Human leptin has natriuretic activity in the rat. Am J Physiol 1997; 272: F333-F338.
    • (1997) Am J Physiol , vol.272
    • Jackson, E.K.1    Li, P.2
  • 348
    • 0032440815 scopus 로고    scopus 로고
    • Renal effects of leptin in normotensive, hypertensive, and obese rats
    • 347. Villarreal D, Reams G, Freeman RH, et al. Renal effects of leptin in normotensive, hypertensive, and obese rats. Am J Physiol 1998; 275: R2056-R2060.
    • (1998) Am J Physiol , vol.275
    • Villarreal, D.1    Reams, G.2    Freeman, R.H.3
  • 349
    • 0032421732 scopus 로고    scopus 로고
    • The obese gene product, leptin: Possible role in obesity-related hypertension in adolescents
    • 348. Hirose H, Saito I, Tsujioka M, et al. The obese gene product, leptin: possible role in obesity-related hypertension in adolescents. J Hypertens 1998; 16: 2007-2012.
    • (1998) J Hypertens , vol.16 , pp. 2007-2012
    • Hirose, H.1    Saito, I.2    Tsujioka, M.3
  • 350
    • 0031808544 scopus 로고    scopus 로고
    • Serum leptin level - Possible association with haematopoiesis in adolescents independent of body mass index and serum insulin
    • 349. Hirose H, Saito I, Kawai T, et al. Serum leptin level - possible association with haematopoiesis in adolescents independent of body mass index and serum insulin. Clin Sci 1998; 94: 633-636.
    • (1998) Clin Sci , vol.94 , pp. 633-636
    • Hirose, H.1    Saito, I.2    Kawai, T.3
  • 351
    • 0031714508 scopus 로고    scopus 로고
    • Relationships between angiotensinogen, leptin and blood pressure levels in young normotensive men
    • 350. Schorr U, Blaschke K, Turan S, et al. Relationships between angiotensinogen, leptin and blood pressure levels in young normotensive men. J Hypertens 1998; 16: 1475-1480.
    • (1998) J Hypertens , vol.16 , pp. 1475-1480
    • Schorr, U.1    Blaschke, K.2    Turan, S.3
  • 352
    • 0031561375 scopus 로고    scopus 로고
    • Serum leptin levels are associated with hyperinsulinemia independent of body mass index but not with visceral obesity
    • 351. Kim-Motoyama H, Yamaguchi T, Katakura T, et al. Serum leptin levels are associated with hyperinsulinemia independent of body mass index but not with visceral obesity. Biochem Biophys Res Commun 1997; 239: 340-344.
    • (1997) Biochem Biophys Res Commun , vol.239 , pp. 340-344
    • Kim-Motoyama, H.1    Yamaguchi, T.2    Katakura, T.3
  • 353
    • 0031775895 scopus 로고    scopus 로고
    • Hyperleptinemia as a component of a metabolic syndrome of cardiovascular risk
    • 352. Leyva F, Godsland IF, Ghatei M, et al. Hyperleptinemia as a component of a metabolic syndrome of cardiovascular risk. Arterioscler Thromb Vasc Biol 1998; 18: 928-933.
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 928-933
    • Leyva, F.1    Godsland, I.F.2    Ghatei, M.3
  • 354
    • 0030943158 scopus 로고    scopus 로고
    • Hyperleptinaemia: The missing link in the metabolic syndrome?
    • 353. De Courten M, Zimmet P, Hodge A, et al. Hyperleptinaemia: the missing link in the metabolic syndrome? Diabetic Med 1997; 14: 200-208.
    • (1997) Diabetic Med , vol.14 , pp. 200-208
    • De Courten, M.1    Zimmet, P.2    Hodge, A.3
  • 355
    • 0031795731 scopus 로고    scopus 로고
    • Is there a role for the ob gene product leptin in essential hypertension?
    • 354. Suter PM, Locher R, Häsler E, et al. Is there a role for the ob gene product leptin in essential hypertension? Am J Hypertens 1998; 11: 1305-1311.
    • (1998) Am J Hypertens , vol.11 , pp. 1305-1311
    • Suter, P.M.1    Locher, R.2    Häsler, E.3
  • 356
    • 0344959452 scopus 로고    scopus 로고
    • Leptin is a risk marker for first-ever hemorrhagic stroke in a population-based cohort
    • 355. Söderberg S, Ahrén B, Stegmayr B, et al. Leptin is a risk marker for first-ever hemorrhagic stroke in a population-based cohort. Stroke 1999; 30: 328-337.
    • (1999) Stroke , vol.30 , pp. 328-337
    • Söderberg, S.1    Ahrén, B.2    Stegmayr, B.3
  • 357
    • 0030996549 scopus 로고    scopus 로고
    • Relationships between plasma leptin and insulin concentrations, but not insulin resistance, in non-insulin-dependent (type 2) diabetes mellitus
    • 356. Mohamed-Ali V, Pinkney JH, Panahloo A, et al. Relationships between plasma leptin and insulin concentrations, but not insulin resistance, in non-insulin-dependent (type 2) diabetes mellitus. Diabetic Med 1997; 14: 76-380.
    • (1997) Diabetic Med , vol.14 , pp. 76-380
    • Mohamed-Ali, V.1    Pinkney, J.H.2    Panahloo, A.3
  • 358
    • 0030699352 scopus 로고    scopus 로고
    • High plasma immunoreactive leptin level in essential hypertension
    • 357. Agata J, Masuda A, Takada M, et al. High plasma immunoreactive leptin level in essential hypertension. Am J Hypertens 1997; 10: 1171-1174.
    • (1997) Am J Hypertens , vol.10 , pp. 1171-1174
    • Agata, J.1    Masuda, A.2    Takada, M.3
  • 359
    • 0033047528 scopus 로고    scopus 로고
    • An independent relationship between plasma leptin and heart rate in untreated patients with essential hypertension
    • 358. Narkiewicz K, Somers VK, Mos L, et al. An independent relationship between plasma leptin and heart rate in untreated patients with essential hypertension. J Hypertens 1999; 17: 245-249.
    • (1999) J Hypertens , vol.17 , pp. 245-249
    • Narkiewicz, K.1    Somers, V.K.2    Mos, L.3
  • 360
    • 0031181808 scopus 로고    scopus 로고
    • Cardiac autonomie nervous system activity in obese and never-obese young men
    • 359. Aronne LJ, Mackintosh R, Rosenbaum M, et al. Cardiac autonomie nervous system activity in obese and never-obese young men. Obesity Res 1997; 5: 354-359.
    • (1997) Obesity Res , vol.5 , pp. 354-359
    • Aronne, L.J.1    Mackintosh, R.2    Rosenbaum, M.3
  • 361
    • 0031179154 scopus 로고    scopus 로고
    • Relationship between muscle sympathetic nerve activity and plasma leptin concentration
    • 360. Snitker S, Pratley RE, Nicolson M, et al. Relationship between muscle sympathetic nerve activity and plasma leptin concentration. Obesity Res 1997; 5: 338-340.
    • (1997) Obesity Res , vol.5 , pp. 338-340
    • Snitker, S.1    Pratley, R.E.2    Nicolson, M.3
  • 362
    • 0030774228 scopus 로고    scopus 로고
    • Regional sympathetic nervous activity and oxygen consumption of obese normotensive human subjects
    • 361. Vaz M, Jennings G, Turner A, et al. Regional sympathetic nervous activity and oxygen consumption of obese normotensive human subjects. Circulation 1997; 96: 3423-3429.
    • (1997) Circulation , vol.96 , pp. 3423-3429
    • Vaz, M.1    Jennings, G.2    Turner, A.3
  • 363
    • 0031915987 scopus 로고    scopus 로고
    • Dissociation between muscle and skin sympathetic nerve activity in essential hypertension, obesity, and congestive heart failure
    • 362. Grassi G, Colombo M, Seravalle G, et al. Dissociation between muscle and skin sympathetic nerve activity in essential hypertension, obesity, and congestive heart failure. Hypertension 1998; 31: 64-67.
    • (1998) Hypertension , vol.31 , pp. 64-67
    • Grassi, G.1    Colombo, M.2    Seravalle, G.3
  • 364
    • 7844225512 scopus 로고    scopus 로고
    • Augmented placental production of leptin in preeclampsia: Possible involvement of placental hypoxia
    • 363. Mise H, Sagawa N, Matsumoto T, et al. Augmented placental production of leptin in preeclampsia: possible involvement of placental hypoxia. J Clin Endocrinol Metab 1998; 83: 3225-3229.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 3225-3229
    • Mise, H.1    Sagawa, N.2    Matsumoto, T.3
  • 365
    • 0032980538 scopus 로고    scopus 로고
    • Maternal plasma leptin is increased in preeclampsia and positively correlates with fetal cord concentration
    • 364. McCarthy JF, Misra DN Roberts JM. Maternal plasma leptin is increased in preeclampsia and positively correlates with fetal cord concentration. Am J Obstet Gynecol 1999; 180: 731-736.
    • (1999) Am J Obstet Gynecol , vol.180 , pp. 731-736
    • McCarthy, J.F.1    Misra, D.N.2    Roberts, J.M.3
  • 366
    • 0029910566 scopus 로고    scopus 로고
    • Preeclampsia - A state of sympathetic overactivity
    • 365. Schobel HP, Fischer T, Heuszer K, et al. Preeclampsia - a state of sympathetic overactivity. N Engl J Med 1996; 335: 1480-1485.
    • (1996) N Engl J Med , vol.335 , pp. 1480-1485
    • Schobel, H.P.1    Fischer, T.2    Heuszer, K.3
  • 367
    • 17344384196 scopus 로고    scopus 로고
    • Multiple cytokines and acute inflammation raise mouse leptin levels: Potential role in inflammatory anorexia
    • 366. Sarraf P, Frederich RC, Turner EM, et al. Multiple cytokines and acute inflammation raise mouse leptin levels: potential role in inflammatory anorexia. J Exp Med 1997; 185: 171-175.
    • (1997) J Exp Med , vol.185 , pp. 171-175
    • Sarraf, P.1    Frederich, R.C.2    Turner, E.M.3
  • 368
    • 0031803271 scopus 로고    scopus 로고
    • Endotoxin-induced alteration in the expression of leptin and β3-adrenergic receptor in adipose tissue
    • 367. Berkowitz DE, Brown D, Lee YM, et al. Endotoxin-induced alteration in the expression of leptin and β3-adrenergic receptor in adipose tissue. Am J Physiol 1998; 274: E992-E997.
    • (1998) Am J Physiol , vol.274
    • Berkowitz, D.E.1    Brown, D.2    Lee, Y.M.3
  • 369
    • 0030806265 scopus 로고    scopus 로고
    • LPS-induced anorexia in leptin-deficient (ob/ob) and leptin receptor-deficient (db/db) mice
    • 368. Faggioni R, Fuller J, Moser A, et al. LPS-induced anorexia in leptin-deficient (ob/ob) and leptin receptor-deficient (db/db) mice. Am J Physiol 1997; 273: R181-R186.
    • (1997) Am J Physiol , vol.273
    • Faggioni, R.1    Fuller, J.2    Moser, A.3
  • 370
    • 0032922204 scopus 로고    scopus 로고
    • Parasite-induced anorexia: Leptin, insulin and corticosterone responses to infection with the nematode, Nippostrongylus brasiliensis
    • 369. Roberts HC, Hardie LJ, Chappell LH, et al. Parasite-induced anorexia: leptin, insulin and corticosterone responses to infection with the nematode, Nippostrongylus brasiliensis. Parasitology 1999; 118: 117-123.
    • (1999) Parasitology , vol.118 , pp. 117-123
    • Roberts, H.C.1    Hardie, L.J.2    Chappell, L.H.3
  • 371
    • 0031768795 scopus 로고    scopus 로고
    • Elevated plasma leptin concentrations in early stages of experimental intestinal inflammation in rats
    • 370. Barbier M, Cherbut C, Aubé AC, et al. Elevated plasma leptin concentrations in early stages of experimental intestinal inflammation in rats. Gut 1998; 43: 783-790.
    • (1998) Gut , vol.43 , pp. 783-790
    • Barbier, M.1    Cherbut, C.2    Aubé, A.C.3
  • 372
    • 0029863684 scopus 로고    scopus 로고
    • Endotoxin and cytokines induce expression of leptin, the ob gene product, in hamsters. A role for leptin in the anorexia of infection
    • 371. Grunfeld C, Zhao C, Fuller J, et al. Endotoxin and cytokines induce expression of leptin, the ob gene product, in hamsters. A role for leptin in the anorexia of infection. J Clin Invest 1996; 97: 2152-2157.
    • (1996) J Clin Invest , vol.97 , pp. 2152-2157
    • Grunfeld, C.1    Zhao, C.2    Fuller, J.3
  • 373
    • 0032039013 scopus 로고    scopus 로고
    • Increased leptin expression in mice with bacterial peritonitis is partially regulated by tumor necrosis factor alpha
    • 372. Moshyedi AK, Josephs MD, Abdalla EK, et al. Increased leptin expression in mice with bacterial peritonitis is partially regulated by tumor necrosis factor alpha. Infect Immun 1998; 66: 1800-1802.
    • (1998) Infect Immun , vol.66 , pp. 1800-1802
    • Moshyedi, A.K.1    Josephs, M.D.2    Abdalla, E.K.3
  • 374
    • 0033580031 scopus 로고    scopus 로고
    • Intracerebroventricular injection of lipopolysaccharide increases plasma leptin levels
    • 373. Finck BN, Johnson RW. Intracerebroventricular injection of lipopolysaccharide increases plasma leptin levels. Neuroreport 1999; 10: 153-156.
    • (1999) Neuroreport , vol.10 , pp. 153-156
    • Finck, B.N.1    Johnson, R.W.2
  • 375
    • 0031769566 scopus 로고    scopus 로고
    • Plasma leptin levels are increased in survivors of acute sepsis: Associated loss of diurnal rhythm in cortisol and leptin secretion
    • 374. Bornstein SR, Licinio J, Tauchnitz R, et al. Plasma leptin levels are increased in survivors of acute sepsis: associated loss of diurnal rhythm in cortisol and leptin secretion. J Clin Endocrinol Metab 1998; 83: 280-283.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 280-283
    • Bornstein, S.R.1    Licinio, J.2    Tauchnitz, R.3
  • 377
    • 0031657189 scopus 로고    scopus 로고
    • Circulating leptin levels during acute experimental endotoxemia and antiinflammatory therapy in humans
    • 376. Bornstein SR, Preas HL, Chrousos GP, et al. Circulating leptin levels during acute experimental endotoxemia and antiinflammatory therapy in humans. J Infect Dis 1998; 178: 887-890.
    • (1998) J Infect Dis , vol.178 , pp. 887-890
    • Bornstein, S.R.1    Preas, H.L.2    Chrousos, G.P.3
  • 378
    • 0032923775 scopus 로고    scopus 로고
    • Serum leptin concentrations and their relation to metabolic abnormalities in human sepsis
    • 377. Carlson GL, Saeed M, Little RA, et al. Serum leptin concentrations and their relation to metabolic abnormalities in human sepsis. Am J Physiol 1999; 276: E658-E662.
    • (1999) Am J Physiol , vol.276
    • Carlson, G.L.1    Saeed, M.2    Little, R.A.3
  • 379
    • 0031836378 scopus 로고    scopus 로고
    • Serum leptin and insulin in paediatric end-stage liver disease and following successful orthotopic liver transplantation
    • 378. Roberts GA, Holt RIG, Ghatel MA, et al. Serum leptin and insulin in paediatric end-stage liver disease and following successful orthotopic liver transplantation. Clin Endocrinol 1998; 48: 401-406.
    • (1998) Clin Endocrinol , vol.48 , pp. 401-406
    • Roberts, G.A.1    Holt, R.I.G.2    Ghatel, M.A.3
  • 380
    • 0031767485 scopus 로고    scopus 로고
    • An increase of circulating leptin in patients with liver cirrhosis
    • 379. Shimizu H, Kakizaki S, Tsuchiya T, et al. An increase of circulating leptin in patients with liver cirrhosis. Int J Obesity 1998; 22: 1234-1238.
    • (1998) Int J Obesity , vol.22 , pp. 1234-1238
    • Shimizu, H.1    Kakizaki, S.2    Tsuchiya, T.3
  • 381
    • 0033048889 scopus 로고    scopus 로고
    • Hyperleptinaemia in young adults following cranial irradiation in childhood: Growth hormone deficiency or leptin insensitivity?
    • 380. Brennan BMD, Rahim A, Blum WF, et al. Hyperleptinaemia in young adults following cranial irradiation in childhood: growth hormone deficiency or leptin insensitivity? Clin Endocrinol 1999; 50: 163-169.
    • (1999) Clin Endocrinol , vol.50 , pp. 163-169
    • Brennan, B.M.D.1    Rahim, A.2    Blum, W.F.3
  • 382
    • 0032433605 scopus 로고    scopus 로고
    • Circulating leptin level and growth hormone response to stimulation tests in obese and normal children
    • 381. Coutant R, Lahlou N, Bouvattier C, et al. Circulating leptin level and growth hormone response to stimulation tests in obese and normal children. Eur J Endocrinol 1998; 139: 591-597.
    • (1998) Eur J Endocrinol , vol.139 , pp. 591-597
    • Coutant, R.1    Lahlou, N.2    Bouvattier, C.3
  • 383
    • 0030745227 scopus 로고    scopus 로고
    • Serum leptin is increased in growth hormone-deficient adults: Relationship to body composition and effects of placebo-controlled growth hormone therapy for 1 year
    • 382. Fisker S, Vahl N, Hansen TB, et al. Serum leptin is increased in growth hormone-deficient adults: relationship to body composition and effects of placebo-controlled growth hormone therapy for 1 year. Metabolism 1997; 46: 812-817.
    • (1997) Metabolism , vol.46 , pp. 812-817
    • Fisker, S.1    Vahl, N.2    Hansen, T.B.3
  • 384
    • 0031673218 scopus 로고    scopus 로고
    • Serum leptin levels and leptin expression in growth hormone (GH)-deficient and healthy adults: Influence of GH treatment, gender and fasting
    • 383. Kristensen K, Pedersen SB, Fisker S, et al. Serum leptin levels and leptin expression in growth hormone (GH)-deficient and healthy adults: influence of GH treatment, gender and fasting. Metabolism 1998; 47: 1514-1519.
    • (1998) Metabolism , vol.47 , pp. 1514-1519
    • Kristensen, K.1    Pedersen, S.B.2    Fisker, S.3
  • 385
    • 0033010892 scopus 로고    scopus 로고
    • Changes in body composition and leptin levels during growth hormone (GH) treatment in short children with various GH secretory capacities
    • 384. Matsuoka H, Fors H, Bosaeus I, et al. Changes in body composition and leptin levels during growth hormone (GH) treatment in short children with various GH secretory capacities. Eur J Endocrinol 1999; 140: 35-42.
    • (1999) Eur J Endocrinol , vol.140 , pp. 35-42
    • Matsuoka, H.1    Fors, H.2    Bosaeus, I.3
  • 386
    • 0031865371 scopus 로고    scopus 로고
    • Increased levels but preserved diurnal variation of serum leptin in GH-deficient patients: Lack of impact of different modes of GH administration
    • 385. Nørrelund H, Gravholt CH, Englaro P, et al. Increased levels but preserved diurnal variation of serum leptin in GH-deficient patients: lack of impact of different modes of GH administration. Eur J Endocrinol 1998; 138: 644-652.
    • (1998) Eur J Endocrinol , vol.138 , pp. 644-652
    • Nørrelund, H.1    Gravholt, C.H.2    Englaro, P.3
  • 387
    • 2642665533 scopus 로고    scopus 로고
    • Serum leptin levels during recombinant human GH therapy in adults with GH deficiency
    • 386. Janssen YJH, Frölich M, Deurenberg P, et al. Serum leptin levels during recombinant human GH therapy in adults with GH deficiency. Eur J Endocrinol 1997; 137: 650-654.
    • (1997) Eur J Endocrinol , vol.137 , pp. 650-654
    • Janssen, Y.J.H.1    Frölich, M.2    Deurenberg, P.3
  • 388
    • 0031786041 scopus 로고    scopus 로고
    • Short-term changes in serum leptin levels provide a strong metabolic marker for the growth response to growth hormone treatment in children
    • 387. Kriström B, Carlsson B, Rosberg S, et al. Short-term changes in serum leptin levels provide a strong metabolic marker for the growth response to growth hormone treatment in children. J Clin Endocrinol Metab 1998; 83: 2735-2741.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 2735-2741
    • Kriström, B.1    Carlsson, B.2    Rosberg, S.3
  • 390
    • 0032407099 scopus 로고    scopus 로고
    • Interaction between body composition, leptin and growth hormone status
    • 389. Casanueva FF, Dieguez C. Interaction between body composition, leptin and growth hormone status. Baillière's Clin Endocrinol Metab 1998; 12: 297-314.
    • (1998) Baillière's Clin Endocrinol Metab , vol.12 , pp. 297-314
    • Casanueva, F.F.1    Dieguez, C.2
  • 391
    • 0032990806 scopus 로고    scopus 로고
    • Short-term fasting suppresses leptin and (conversely) activates disorderly growth hormone secretion in midluteal phase women - A clinical research center study
    • 390. Bergendahl M, Evans WS, Pastor C, et al. Short-term fasting suppresses leptin and (conversely) activates disorderly growth hormone secretion in midluteal phase women - a clinical research center study. J Clin Endocrinol Metab 1999; 84: 883-894.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 883-894
    • Bergendahl, M.1    Evans, W.S.2    Pastor, C.3
  • 392
    • 0031761830 scopus 로고    scopus 로고
    • Leptin is a potent stimulator of spontaneous pulsatile growth hormone (GH) secretion and the GH response to GH-releasing hormone
    • 391. Tannenbaum GS, Gurd W Lapointe M. Leptin is a potent stimulator of spontaneous pulsatile growth hormone (GH) secretion and the GH response to GH-releasing hormone. Endocrinology 1998; 139: 3871-3875.
    • (1998) Endocrinology , vol.139 , pp. 3871-3875
    • Tannenbaum, G.S.1    Gurd, W.2    Lapointe, M.3
  • 393
    • 0031961399 scopus 로고    scopus 로고
    • Evidence for a leptin-neuropeptide Y axis for the regulation of growth hormone secretion in the rat
    • 392. Vuagnat BAM, Pierroz DD, Lalaoui M, et al. Evidence for a leptin-neuropeptide Y axis for the regulation of growth hormone secretion in the rat. Neuroendocrinology 1998; 67: 291-300.
    • (1998) Neuroendocrinology , vol.67 , pp. 291-300
    • Vuagnat, B.A.M.1    Pierroz, D.D.2    Lalaoui, M.3
  • 394
    • 0031732754 scopus 로고    scopus 로고
    • Leptin levels, β-cell function, and insulin sensitivity in families with congenital and acquired generalized lipoatropic diabetes
    • 393. Pardini VC, Victória IMN, Rocha SMV, et al. Leptin levels, β-cell function, and insulin sensitivity in families with congenital and acquired generalized lipoatropic diabetes. J Clin Endocrinol Metab 1998; 83: 503-508.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 503-508
    • Pardini, V.C.1    Victória, I.M.N.2    Rocha, S.M.V.3
  • 395
    • 0033016192 scopus 로고    scopus 로고
    • Extremely low values of serum leptin in children with congenital generalized lipoatrophy
    • 394. Jaquet D, Khallou E, Lévy-Marchal C, et al. Extremely low values of serum leptin in children with congenital generalized lipoatrophy. Eur J Endocrinol 1999; 140: 107-109.
    • (1999) Eur J Endocrinol , vol.140 , pp. 107-109
    • Jaquet, D.1    Khallou, E.2    Lévy-Marchal, C.3
  • 396
    • 0029895842 scopus 로고    scopus 로고
    • Generalized lipodystrophy, congenital and acquired (lipoatrophy)
    • 395. Seip M, Trygstad O. Generalized lipodystrophy, congenital and acquired (lipoatrophy). Acta Paediatr 1996; Suppl 413: 2-28.
    • (1996) Acta Paediatr , Issue.SUPPL. 413 , pp. 2-28
    • Seip, M.1    Trygstad, O.2
  • 397
    • 0018646961 scopus 로고
    • The effect of diet on thermogenesis in acquired lipodystrophy
    • 396. Robbins DC, Danforth E Jr, Horton ES, et al. The effect of diet on thermogenesis in acquired lipodystrophy. Metabolism 1979; 28: 908-916.
    • (1979) Metabolism , vol.28 , pp. 908-916
    • Robbins, D.C.1    Danforth E., Jr.2    Horton, E.S.3
  • 398
    • 0032532753 scopus 로고    scopus 로고
    • Life without white fat: A transgenic mouse
    • 397. Moitra J, Mason MM, Olive M, et al. Life without white fat: a transgenic mouse. Genes Dev 1998; 12: 3168-3181.
    • (1998) Genes Dev , vol.12 , pp. 3168-3181
    • Moitra, J.1    Mason, M.M.2    Olive, M.3
  • 400
    • 0032532152 scopus 로고    scopus 로고
    • Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: Model for congenital generalized lipodystrophy
    • 399. Shimomura I, Hammer RE, Richardson JA, et al. Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy. Genes Dev 1998; 12: 3182-3194.
    • (1998) Genes Dev , vol.12 , pp. 3182-3194
    • Shimomura, I.1    Hammer, R.E.2    Richardson, J.A.3
  • 402
    • 0031797440 scopus 로고    scopus 로고
    • Plasma leptin levels in trauma patients: Effect of adjuvant recombinant human growth hormone in intravenously fed multiple trauma patients
    • 401. Jeevanandam M, Begay CK Petersen SR. Plasma leptin levels in trauma patients: effect of adjuvant recombinant human growth hormone in intravenously fed multiple trauma patients. J Parent Ent Nutr 1998; 22: 340-346.
    • (1998) J Parent Ent Nutr , vol.22 , pp. 340-346
    • Jeevanandam, M.1    Begay, C.K.2    Petersen, S.R.3
  • 403
    • 0031926272 scopus 로고    scopus 로고
    • Plasma leptin in chronic inflammatory bowel disease and HIV: Implications for the pathogenesis of anorexia and weight loss
    • 402. Ballinger A, Kelly P, Hallyburton E, et al. Plasma leptin in chronic inflammatory bowel disease and HIV: implications for the pathogenesis of anorexia and weight loss. Clin Sci 1998; 94: 479-483.
    • (1998) Clin Sci , vol.94 , pp. 479-483
    • Ballinger, A.1    Kelly, P.2    Hallyburton, E.3
  • 404
    • 0029797813 scopus 로고    scopus 로고
    • Serum leptin levels in the acquired immunodeficiency syndrome
    • 403. Grunfeld C, Pang M, Shigenaga JK, et al. Serum leptin levels in the acquired immunodeficiency syndrome. J Clin Endocrinol Metab 1996; 81: 4342-4346.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 4342-4346
    • Grunfeld, C.1    Pang, M.2    Shigenaga, J.K.3
  • 405
    • 0031719465 scopus 로고    scopus 로고
    • Determinants of increased energy expenditure in HIV-infected women
    • 404. Grinspoon SK, Corcoran C, Miller K, et al. Determinants of increased energy expenditure in HIV-infected women. Am J Clin Nutr 1998; 68: 720-725.
    • (1998) Am J Clin Nutr , vol.68 , pp. 720-725
    • Grinspoon, S.K.1    Corcoran, C.2    Miller, K.3
  • 406
    • 0031024791 scopus 로고    scopus 로고
    • Serum leptin concentrations in human immunodeficiency virus-infected men with low adiposity
    • 405. Yarasheski KE, Zachwieja JJ, Horgan MM, et al. Serum leptin concentrations in human immunodeficiency virus-infected men with low adiposity. Metabolism 1997; 46: 303-305.
    • (1997) Metabolism , vol.46 , pp. 303-305
    • Yarasheski, K.E.1    Zachwieja, J.J.2    Horgan, M.M.3
  • 407
    • 0030886382 scopus 로고    scopus 로고
    • Plasma concentration of total leptin and human lung-cancer-associated cachexia
    • 406. Simons JPFHA, Schols AMWJ, Campfield LA, et al. Plasma concentration of total leptin and human lung-cancer-associated cachexia. Clin Sci 1997; 93: 273-277.
    • (1997) Clin Sci , vol.93 , pp. 273-277
    • Simons, J.P.F.H.A.1    Schols, A.M.W.J.2    Campfield, L.A.3
  • 408
    • 0032407098 scopus 로고    scopus 로고
    • Effect of weight loss and the inflammatory response on leptin concentrations in gastrointestinal cancer patients
    • 407. Wallace AM, Sattar N McMillan DC. Effect of weight loss and the inflammatory response on leptin concentrations in gastrointestinal cancer patients. Clin Cancer Res 1998; 4: 2977-2979.
    • (1998) Clin Cancer Res , vol.4 , pp. 2977-2979
    • Wallace, A.M.1    Sattar, N.2    McMillan, D.C.3
  • 409
    • 0030774164 scopus 로고    scopus 로고
    • Low circulating leptin levels in protein-energy malnourished chronically ill elderly patients
    • 408. Cederholm T, Arner P Palmblad J. Low circulating leptin levels in protein-energy malnourished chronically ill elderly patients. J Int Med 1997; 242: 377-382.
    • (1997) J Int Med , vol.242 , pp. 377-382
    • Cederholm, T.1    Arner, P.2    Palmblad, J.3
  • 410
    • 0030899777 scopus 로고    scopus 로고
    • Plasma leptin concentrations and energy expenditure in heart failure patients
    • 409. Toth MJ, Gottlieb SS, Fisher ML, et al. Plasma leptin concentrations and energy expenditure in heart failure patients. Metabolism 1997; 46: 450-453.
    • (1997) Metabolism , vol.46 , pp. 450-453
    • Toth, M.J.1    Gottlieb, S.S.2    Fisher, M.L.3
  • 411
    • 0032189670 scopus 로고    scopus 로고
    • Hyperleptinaemia in chronic heart failure. Relationships with insulin
    • 410. Leyva F, Anker SD, Egerer K, et al. Hyperleptinaemia in chronic heart failure. Relationships with insulin. Eur Heart J 1998; 19: 1547-1551.
    • (1998) Eur Heart J , vol.19 , pp. 1547-1551
    • Leyva, F.1    Anker, S.D.2    Egerer, K.3
  • 412
    • 0031708220 scopus 로고    scopus 로고
    • Leptin and cardiac cachexia: Marker or mediator?
    • 411. Cleland JGF, Clark AL. Leptin and cardiac cachexia: marker or mediator? Eur Heart J 1998; 19: 1421-1422.
    • (1998) Eur Heart J , vol.19 , pp. 1421-1422
    • Cleland, J.G.F.1    Clark, A.L.2
  • 413
    • 0032905953 scopus 로고    scopus 로고
    • Total parenteral nutrition increases serum leptin concentration in hospitalized, undernourished patients
    • 412. LeGall-Salmon E, Stevens WD Levy JR. Total parenteral nutrition increases serum leptin concentration in hospitalized, undernourished patients. J Parent Ent Nutr 1999; 23: 38-42.
    • (1999) J Parent Ent Nutr , vol.23 , pp. 38-42
    • LeGall-Salmon, E.1    Stevens, W.D.2    Levy, J.R.3
  • 414
    • 0033008979 scopus 로고    scopus 로고
    • Serum leptin and gonadotropin levels in patients with anorexia nervosa during weight gain
    • 413. Ballauff A, Ziegler A, Emons G, et al. Serum leptin and gonadotropin levels in patients with anorexia nervosa during weight gain. Mol Psychiatry 1999; 4: 71-75.
    • (1999) Mol Psychiatry , vol.4 , pp. 71-75
    • Ballauff, A.1    Ziegler, A.2    Emons, G.3
  • 416
    • 0031766810 scopus 로고    scopus 로고
    • Leptin in relation to resumption of menses in women with anorexia nervosa
    • 415. Audi L, Mantzoros C, Vidal-Puig A, et al. Leptin in relation to resumption of menses in women with anorexia nervosa. Mol Psychiatry 1998; 3: 544-547.
    • (1998) Mol Psychiatry , vol.3 , pp. 544-547
    • Audi, L.1    Mantzoros, C.2    Vidal-Puig, A.3
  • 417
    • 9844268513 scopus 로고    scopus 로고
    • Leptin levels in patients with anorexia nervosa are reduced in the acute state and elevated upon short-term restoration
    • 416. Hebebrand J, Blum WF, Barth N, et al. Leptin levels in patients with anorexia nervosa are reduced in the acute state and elevated upon short-term restoration. Mol Psychiatry 1997; 2: 330-334.
    • (1997) Mol Psychiatry , vol.2 , pp. 330-334
    • Hebebrand, J.1    Blum, W.F.2    Barth, N.3
  • 418
    • 9844246447 scopus 로고    scopus 로고
    • Low leptin levels predict amenorrhea in underweight and eating disordered females
    • 417. Köpp W, Blum WF, von Prittwitz S, et al. Low leptin levels predict amenorrhea in underweight and eating disordered females. Mol Psychiatry 1997; 2: 335-360.
    • (1997) Mol Psychiatry , vol.2 , pp. 335-360
    • Köpp, W.1    Blum, W.F.2    Von Prittwitz, S.3
  • 419
    • 0033042915 scopus 로고    scopus 로고
    • Leptin in women with eating disorders
    • 418. Nakai Y, Hamagaki S, Kato S, et al. Leptin in women with eating disorders. Metabolism 1999; 48: 217-220.
    • (1999) Metabolism , vol.48 , pp. 217-220
    • Nakai, Y.1    Hamagaki, S.2    Kato, S.3
  • 420
    • 0033064507 scopus 로고    scopus 로고
    • Functional hypothalamic amenorrhea: Hypoleptinemia and disordered eating
    • 419. Warren MP, Voussoughian F, Geer EB, et al. Functional hypothalamic amenorrhea: hypoleptinemia and disordered eating. J Clin Endocrinol Metab 1999; 84: 873-877.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 873-877
    • Warren, M.P.1    Voussoughian, F.2    Geer, E.B.3
  • 421
    • 0031769358 scopus 로고    scopus 로고
    • Leptin and the thyroid - A puzzle with missing pieces
    • 420. Korbonits M. Leptin and the thyroid - a puzzle with missing pieces. Clin Endocrinol 1998; 49: 569-572.
    • (1998) Clin Endocrinol , vol.49 , pp. 569-572
    • Korbonits, M.1
  • 422
    • 0031832836 scopus 로고    scopus 로고
    • The interaction between leptin and the hypothalamic-pituitary-thyroid axis
    • 421. Orban Z, Bornstein SR Chrousos GP. The interaction between leptin and the hypothalamic-pituitary-thyroid axis. Horm Metab Res 1998; 30: 231-235.
    • (1998) Horm Metab Res , vol.30 , pp. 231-235
    • Orban, Z.1    Bornstein, S.R.2    Chrousos, G.P.3
  • 423
    • 0031794524 scopus 로고    scopus 로고
    • Leptin and the pituitary-thyroid axis: A comparative study in lean, obese, hypothyroid and hyperthyroid subjects
    • 422. Pinkney JH, Goodrick SJ, Katz J, et al. Leptin and the pituitary-thyroid axis: a comparative study in lean, obese, hypothyroid and hyperthyroid subjects. Clin Endocrinol 1998; 49: 583-588.
    • (1998) Clin Endocrinol , vol.49 , pp. 583-588
    • Pinkney, J.H.1    Goodrick, S.J.2    Katz, J.3
  • 424
    • 0031977513 scopus 로고    scopus 로고
    • Serum leptin levels in hypo-and hyperthyroidism
    • 423. Leonhardt U, Ritzel U, Schäfer G, et al. Serum leptin levels in hypo-and hyperthyroidism. J Endocrinol 1998; 157: 75-79.
    • (1998) J Endocrinol , vol.157 , pp. 75-79
    • Leonhardt, U.1    Ritzel, U.2    Schäfer, G.3
  • 425
    • 0031848937 scopus 로고    scopus 로고
    • The effect of thyroid status on plasma leptin levels in women
    • 424. Ozata M, Ozisik G, Bingol N, et al. The effect of thyroid status on plasma leptin levels in women. J Endocrinol Invest 1998; 21: 337-341.
    • (1998) J Endocrinol Invest , vol.21 , pp. 337-341
    • Ozata, M.1    Ozisik, G.2    Bingol, N.3
  • 426
    • 0031883731 scopus 로고    scopus 로고
    • Serum leptin concentrations in patients with thyroid disorders
    • 425. Yoshida T, Momotani N, Hayashi M, et al. Serum leptin concentrations in patients with thyroid disorders. Clin Endocrinol 1998; 48: 299-302.
    • (1998) Clin Endocrinol , vol.48 , pp. 299-302
    • Yoshida, T.1    Momotani, N.2    Hayashi, M.3
  • 427
    • 0032424554 scopus 로고    scopus 로고
    • Thyroid hormones modulate serum leptin levels: Observations in thyrotoxic and hypothyroid women
    • 426. Diekman MJM, Romijn JA, Endert E, et al. Thyroid hormones modulate serum leptin levels: observations in thyrotoxic and hypothyroid women. Thyroid 1998; 8: 1081-1086.
    • (1998) Thyroid , vol.8 , pp. 1081-1086
    • Diekman, M.J.M.1    Romijn, J.A.2    Endert, E.3
  • 428
    • 0032920516 scopus 로고    scopus 로고
    • Elevation of plasma leptin concentrations in obese hyperinsulinaemic hypothyroidism before and after treatment
    • 427. Kautzky-Willer A, Ludwig C, Nowotny P, et al. Elevation of plasma leptin concentrations in obese hyperinsulinaemic hypothyroidism before and after treatment. Eur J Clin Invest 1999; 29: 395-403.
    • (1999) Eur J Clin Invest , vol.29 , pp. 395-403
    • Kautzky-Willer, A.1    Ludwig, C.2    Nowotny, P.3
  • 429
    • 0031450240 scopus 로고    scopus 로고
    • Lack of effects of circulating thyroid hormone levels on serum leptin concentrations
    • 428. Corbetta S, Englaro P, Giambona S, et al. Lack of effects of circulating thyroid hormone levels on serum leptin concentrations. Eur J Endocrinol 1997; 137: 659-663.
    • (1997) Eur J Endocrinol , vol.137 , pp. 659-663
    • Corbetta, S.1    Englaro, P.2    Giambona, S.3
  • 430
    • 0031756208 scopus 로고    scopus 로고
    • Role of thyroid hormones on serum leptin levels
    • 429. Sesmilo G, Casamitjana R, Halperin I, et al. Role of thyroid hormones on serum leptin levels. Eur J Endocrinol 1998; 139: 428-430.
    • (1998) Eur J Endocrinol , vol.139 , pp. 428-430
    • Sesmilo, G.1    Casamitjana, R.2    Halperin, I.3
  • 431
    • 0032978472 scopus 로고    scopus 로고
    • Reproducibility of fasting plasma leptin concentration in lean and obese humans
    • 430. Liu J, Askari H Dagogo-Jack S. Reproducibility of fasting plasma leptin concentration in lean and obese humans. Endocr Res 1999; 25: 1-10.
    • (1999) Endocr Res , vol.25 , pp. 1-10
    • Liu, J.1    Askari, H.2    Dagogo-Jack, S.3
  • 432
    • 0031050415 scopus 로고    scopus 로고
    • Relatively low plasma leptin concentrations precede weight gain in Pima Indians
    • 431. Ravussin E, Pratley RE, Maffei M, et al. Relatively low plasma leptin concentrations precede weight gain in Pima Indians. Nat Med 1997; 3: 238-240.
    • (1997) Nat Med , vol.3 , pp. 238-240
    • Ravussin, E.1    Pratley, R.E.2    Maffei, M.3
  • 433
    • 0032929898 scopus 로고    scopus 로고
    • Leptin and total cholesterol are predictors of weight gain in pre-pubertal children
    • 432. Byrnes SE, Baur LA, Bermingham M, et al. Leptin and total cholesterol are predictors of weight gain in pre-pubertal children. Int J Obesity 1999; 23: 146-150.
    • (1999) Int J Obesity , vol.23 , pp. 146-150
    • Byrnes, S.E.1    Baur, L.A.2    Bermingham, M.3
  • 434
    • 0032610704 scopus 로고    scopus 로고
    • Serum leptin and weight gain over 8 years in African American and Caucasian young adults
    • 433. Folsom AR, Jensen MD, Jacobs DR Jr, et al. Serum leptin and weight gain over 8 years in African American and Caucasian young adults. Obesity Res 1999; 7: 1-8.
    • (1999) Obesity Res , vol.7 , pp. 1-8
    • Folsom, A.R.1    Jensen, M.D.2    Jacobs D.R., Jr.3
  • 435
    • 0030850740 scopus 로고    scopus 로고
    • Loss of body fat in lean parabiotic partners of ob/ob mice
    • 434. Harris RBS. Loss of body fat in lean parabiotic partners of ob/ob mice. Am J Physiol 1997; 272: R1809-R1815.
    • (1997) Am J Physiol , vol.272
    • Harris, R.B.S.1
  • 436
    • 0032952846 scopus 로고    scopus 로고
    • Parabiosis between db/db and ob/ob or db/+ mice
    • 435. Harris RBS. Parabiosis between db/db and ob/ob or db/+ mice. Endocrinology 1999; 140: 138-145.
    • (1999) Endocrinology , vol.140 , pp. 138-145
    • Harris, R.B.S.1
  • 437
    • 0031793560 scopus 로고    scopus 로고
    • Leptin does not fully account for the satiety activity of adipose tissue-conditioned medium
    • 436. Weigle DS, Hutson AM, Kramer JM, et al. Leptin does not fully account for the satiety activity of adipose tissue-conditioned medium. Am J Physiol 1998; 275: R976-R985.
    • (1998) Am J Physiol , vol.275
    • Weigle, D.S.1    Hutson, A.M.2    Kramer, J.M.3
  • 438
    • 0002342632 scopus 로고    scopus 로고
    • Brown adipose tissue (BAT): Role in energy expenditure and intake
    • Ailhaud G, Guy-Grand B, eds. London: John Libbey
    • 437. Himms-Hagen J. Brown adipose tissue (BAT): role in energy expenditure and intake. In: Ailhaud G, Guy-Grand B, eds. Progress in obesity research: 8. London: John Libbey, Pp. 27-31, 1999.
    • (1999) Progress in Obesity Research: 8 , vol.8 , pp. 27-31
    • Himms-Hagen, J.1
  • 439
    • 0033304576 scopus 로고    scopus 로고
    • Human leptin deficiency caused by a missense mutation: Multiple endocrine defects, decreased sympathetic tone, and immune system dysfunction indicate new targets for leptin action, greater central than peripheral resistance to the effects of leptin, and spontaneous correction of leptin-mediated defects
    • 438. Ozata M, Ozdemir IC Licinio J. Human leptin deficiency caused by a missense mutation: multiple endocrine defects, decreased sympathetic tone, and immune system dysfunction indicate new targets for leptin action, greater central than peripheral resistance to the effects of leptin, and spontaneous correction of leptin-mediated defects. J Clin Endocrinol Metabol 1999; 84: 3686-95.
    • (1999) J Clin Endocrinol Metabol , vol.84 , pp. 3686-3695
    • Ozata, M.1    Ozdemir, I.C.2    Licinio, J.3
  • 440
    • 0033575993 scopus 로고    scopus 로고
    • Effects of recombinant leptin therapy in a child with congenital leptin deficiency
    • 439. Farooqi IS, Jebb SA, Langmack G, et al. Effects of recombinant leptin therapy in a child with congenital leptin deficiency. N Engl J Med 1999; 341: 879-84.
    • (1999) N Engl J Med , vol.341 , pp. 879-884
    • Farooqi, I.S.1    Jebb, S.A.2    Langmack, G.3
  • 441
    • 0032747280 scopus 로고    scopus 로고
    • Recombinant leptin for weight loss in obese and lean adults. A randomized, controlled, dose-escalation trial
    • 440. Heymsfield SB, Greenberg AS, Fujioka K, et al. Recombinant leptin for weight loss in obese and lean adults. A randomized, controlled, dose-escalation trial. JAMA 1999; 282: 1568-75.
    • (1999) JAMA , vol.282 , pp. 1568-1575
    • Heymsfield, S.B.1    Greenberg, A.S.2    Fujioka, K.3


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