-
1
-
-
0029066265
-
Effects of the obese gene product on body weight regulation in ob/ob mice
-
Pelleymounter MA, Cullen MJ, Baker MB, et al. 1995 Effects of the obese gene product on body weight regulation in ob/ob mice. Science. 269:540-543.
-
(1995)
Science
, vol.269
, pp. 540-543
-
-
Pelleymounter, M.A.1
Cullen, M.J.2
Baker, M.B.3
-
2
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang Y, Proenca R, Maffei M, et al. 1994 Positional cloning of the mouse obese gene and its human homologue. Nature. 372:425-432.
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
-
3
-
-
0030010388
-
Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin
-
Chehab FF, Lim ME, Lu R. 1996 Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin. Nat Genet. 12:318-320.
-
(1996)
Nat Genet
, vol.12
, pp. 318-320
-
-
Chehab, F.F.1
Lim, M.E.2
Lu, R.3
-
4
-
-
0029048408
-
Recombinant mouse ob protein: Evidence for a peripheral signal linking adiposity and central neural networks
-
Campfield LA, Smith FJ, Guisez Y, Devos R, Burn P. 1995 Recombinant mouse ob protein: evidence for a peripheral signal linking adiposity and central neural networks. Science. 269:546-549.
-
(1995)
Science
, vol.269
, pp. 546-549
-
-
Campfield, L.A.1
Smith, F.J.2
Guisez, Y.3
Devos, R.4
Burn, P.5
-
5
-
-
0029073613
-
Weight-reducing effects of the plasma protein encoded by the obese gene
-
Halaas JL, Gajiwala KS, Maffei M, et al. 1995 Weight-reducing effects of the plasma protein encoded by the obese gene. Science. 269:543-546.
-
(1995)
Science
, vol.269
, pp. 543-546
-
-
Halaas, J.L.1
Gajiwala, K.S.2
Maffei, M.3
-
6
-
-
0018139377
-
Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice
-
Coleman DL. 1978 Obese and diabetes: two mutant genes causing diabetes-obesity syndromes in mice. Diabetologia. 14:141-148.
-
(1978)
Diabetologia
, vol.14
, pp. 141-148
-
-
Coleman, D.L.1
-
7
-
-
13344259300
-
Evidence that the diabetes gene encodes the leptin receptor: Identification of a mutation in the leptin receptor gene in db/db mice
-
Chen H, Charlat O, Tartaglia LA, et al. 1996 Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice. Cell. 84:491-495.
-
(1996)
Cell
, vol.84
, pp. 491-495
-
-
Chen, H.1
Charlat, O.2
Tartaglia, L.A.3
-
8
-
-
0030039272
-
Abnormal splicing of the leptin receptor in diabetic mice
-
Lee G-H, Proenca R, Montez JM, et al. 1996 Abnormal splicing of the leptin receptor in diabetic mice. Nature. 379:632-635.
-
(1996)
Nature
, vol.379
, pp. 632-635
-
-
Lee, G.-H.1
Proenca, R.2
Montez, J.M.3
-
9
-
-
0030028959
-
Phenotypes of mouse diabetes and rat fatty due to mutations in the ob leptin receptor
-
Chua Jr SC, Chung WK, Wu-Peng XS. 1996 Phenotypes of mouse diabetes and rat fatty due to mutations in the ob leptin receptor. Science. 271:994-996.
-
(1996)
Science
, vol.271
, pp. 994-996
-
-
Chua Jr., S.C.1
Chung, W.K.2
Wu-Peng, X.S.3
-
10
-
-
0030015417
-
Defective STAT signaling by the leptin receptor in the diabetic mice
-
Ghilardi N, Ziegler S, Wiestner A, et al. 1996 Defective STAT signaling by the leptin receptor in the diabetic mice. Proc Natl Acad Sci USA. 93:6231-6235.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 6231-6235
-
-
Ghilardi, N.1
Ziegler, S.2
Wiestner, A.3
-
11
-
-
0029020677
-
Evidence against either a premature stop codon or the absence of obese gene mRNA in human obesity
-
Considine RV, Considine EL, Williams CJ, et al. 1995 Evidence against either a premature stop codon or the absence of obese gene mRNA in human obesity. J Clin Invest. 94:2986-2988.
-
(1995)
J Clin Invest
, vol.94
, pp. 2986-2988
-
-
Considine, R.V.1
Considine, E.L.2
Williams, C.J.3
-
12
-
-
13344295079
-
Serum immunoreactive leptin concentrations in normal weight and obese humans
-
Considine RV, Sinha MK, Heiman ML, et al. 1995 Serum immunoreactive leptin concentrations in normal weight and obese humans. N Engl J Med. 834:292-295.
-
(1995)
N Engl J Med
, vol.834
, pp. 292-295
-
-
Considine, R.V.1
Sinha, M.K.2
Heiman, M.L.3
-
13
-
-
0028845877
-
Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects
-
Maffei M, Halaas J, Ravussin E, et al. 1995 Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat Med. 1:1155-1161.
-
(1995)
Nat Med
, vol.1
, pp. 1155-1161
-
-
Maffei, M.1
Halaas, J.2
Ravussin, E.3
-
14
-
-
0029083859
-
Increased obese mRNA expression in omental fat cells from massively obese humans
-
Hamilton BS, Paglia D, Kwan AYM, et al. 1995 Increased obese mRNA expression in omental fat cells from massively obese humans. Nat Med. 1:953-956.
-
(1995)
Nat Med
, vol.1
, pp. 953-956
-
-
Hamilton, B.S.1
Paglia, D.2
Kwan, A.Y.M.3
-
15
-
-
0024160877
-
Role of insulin resistance and human disease
-
Reaven GM. 1988 Role of insulin resistance and human disease. Diabetes. 37:1595-1607.
-
(1988)
Diabetes
, vol.37
, pp. 1595-1607
-
-
Reaven, G.M.1
-
16
-
-
0018602014
-
Classification and diagnosis of diabetes and other categories of glucose intolerance
-
National Diabetes Data Group. 1979 Classification and diagnosis of diabetes and other categories of glucose intolerance. Diabetes. 28:1039-1057.
-
(1979)
Diabetes
, vol.28
, pp. 1039-1057
-
-
-
17
-
-
0018520840
-
Glucose clamp technique: A method for quantifying insulin secretion and resistance
-
DeFronzo RA, Tobin JD, Andres R. 1979 Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol. 237:E214-E223.
-
(1979)
Am J Physiol
, vol.237
-
-
DeFronzo, R.A.1
Tobin, J.D.2
Andres, R.3
-
18
-
-
0020684724
-
Regulation of splanchnic and peripheral glucose uptake by insulin and hyperglycemia in man
-
DeFronzo RA, Ferrannini E, Hendler R, Felig P, Wahren J. 1983 Regulation of splanchnic and peripheral glucose uptake by insulin and hyperglycemia in man. Diabetes. 32:35-45.
-
(1983)
Diabetes
, vol.32
, pp. 35-45
-
-
DeFronzo, R.A.1
Ferrannini, E.2
Hendler, R.3
Felig, P.4
Wahren, J.5
-
19
-
-
0002809705
-
Animal calorimetry: An analysis of oxidation of mixture of carbohydrate and fat
-
Lusk G. Animal calorimetry: an analysis of oxidation of mixture of carbohydrate and fat. J Biol Chem. 49:41-42.
-
J Biol Chem
, vol.49
, pp. 41-42
-
-
Lusk, G.1
-
20
-
-
0023851885
-
Reduced rate of energy expenditure as a risk factor for body weight gain
-
Ravussin E., Lillioja S, Knowler WC, et al. 1988 Reduced rate of energy expenditure as a risk factor for body weight gain. N Engl J Med. 318:467-472.
-
(1988)
N Engl J Med
, vol.318
, pp. 467-472
-
-
Ravussin, E.1
Lillioja, S.2
Knowler, W.C.3
-
21
-
-
0022524937
-
Variance weighting functions in radioimmunoassay calibration
-
Gettys TW, Burrows PM, Hendricks DM. 1986 Variance weighting functions in radioimmunoassay calibration. Am J Physiol. 251:E357-E361.
-
(1986)
Am J Physiol
, vol.251
-
-
Gettys, T.W.1
Burrows, P.M.2
Hendricks, D.M.3
-
22
-
-
0025047553
-
Skeletal muscle metabolism is a major determinant of resting energy expenditure
-
Zurlo F, Larson K, Bogardus C, Ravussin E. 1990 Skeletal muscle metabolism is a major determinant of resting energy expenditure. J Clin Invest. 86:1423-1427.
-
(1990)
J Clin Invest
, vol.86
, pp. 1423-1427
-
-
Zurlo, F.1
Larson, K.2
Bogardus, C.3
Ravussin, E.4
-
23
-
-
0010404632
-
Muscle GLUT4 expression is a familial trait and determines insulin sensitivity in humans independent of obesity
-
Garvey WT, Maianu L, Brechtel G, Johnson A, Sunblad K, Hardin D. 1994 Muscle GLUT4 expression is a familial trait and determines insulin sensitivity in humans independent of obesity. Diabetes. [Suppl.] 43:69A.
-
(1994)
Diabetes. [Suppl.]
, vol.43
-
-
Garvey, W.T.1
Maianu, L.2
Brechtel, G.3
Johnson, A.4
Sunblad, K.5
Hardin, D.6
-
24
-
-
0026506910
-
Pima Indians as a model to study the genetics of NIDDM
-
Bogardus C, Lilioja S. 1992 Pima Indians as a model to study the genetics of NIDDM. J Cell Biochem. 48:337-343.
-
(1992)
J Cell Biochem
, vol.48
, pp. 337-343
-
-
Bogardus, C.1
Lilioja, S.2
-
25
-
-
0023188310
-
Variations in insulin stimulated glucose uptake in healthy individuals with normal glucose tolerance
-
Hollenbeck C, Reaven GM. 1987 Variations in insulin stimulated glucose uptake in healthy individuals with normal glucose tolerance. J Clin Endocrinol Metab. 64:1169-1173.
-
(1987)
J Clin Endocrinol Metab
, vol.64
, pp. 1169-1173
-
-
Hollenbeck, C.1
Reaven, G.M.2
-
26
-
-
0022500793
-
In vivo kinetics of insulin action on peripheral glucose disposal and hepatic glucose output in normal and obese subjects
-
Prager R., Wallace P, Olefsky J. 1986 In vivo kinetics of insulin action on peripheral glucose disposal and hepatic glucose output in normal and obese subjects. J Clin Invest. 78:472-481.
-
(1986)
J Clin Invest
, vol.78
, pp. 472-481
-
-
Prager, R.1
Wallace, P.2
Olefsky, J.3
-
27
-
-
0028846631
-
Effects of obesity on insulin resistance in normal subjects and patients with NIDDM
-
Ludvik B, Nolan JJ, Balaga J, Sacks D, Olefsky J. 1995 Effects of obesity on insulin resistance in normal subjects and patients with NIDDM. Diabetes. 44:1121-1125.
-
(1995)
Diabetes
, vol.44
, pp. 1121-1125
-
-
Ludvik, B.1
Nolan, J.J.2
Balaga, J.3
Sacks, D.4
Olefsky, J.5
-
28
-
-
0030022018
-
Decreased androgen levels and obesity in men
-
Vermeulen A. 1996 Decreased androgen levels and obesity in men. Ann Med. 28:13-15.
-
(1996)
Ann Med
, vol.28
, pp. 13-15
-
-
Vermeulen, A.1
-
29
-
-
0029941697
-
Radioimmunoassay of leptin in human plasma
-
Ma Z, Gingerich RL, Santiago JV, et al. 1996 Radioimmunoassay of leptin in human plasma. Clin Chem. 42:942-946.
-
(1996)
Clin Chem
, vol.42
, pp. 942-946
-
-
Ma, Z.1
Gingerich, R.L.2
Santiago, J.V.3
-
30
-
-
0028037635
-
The independent effects of polycystic ovary syndrome and obesity on serum concentrations of gonadotrophins and sex steroids in premenopausal women
-
Oxf
-
Holte J, Bergh T, Gennarelli G, Wide L. 1994 The independent effects of polycystic ovary syndrome and obesity on serum concentrations of gonadotrophins and sex steroids in premenopausal women. Clin Endocrinol (Oxf). 41:473-481.
-
(1994)
Clin Endocrinol
, vol.41
, pp. 473-481
-
-
Holte, J.1
Bergh, T.2
Gennarelli, G.3
Wide, L.4
-
31
-
-
0017257149
-
Some aspects of hypothalamic-pituitary function in patients with anorexia nervosa
-
Copenh
-
Travaglini P, Beck-Peccoz P, Ferrari C, et al. 1976 Some aspects of hypothalamic-pituitary function in patients with anorexia nervosa. Acta Endocrinol (Copenh). 81:252-262.
-
(1976)
Acta Endocrinol
, vol.81
, pp. 252-262
-
-
Travaglini, P.1
Beck-Peccoz, P.2
Ferrari, C.3
-
32
-
-
84958689411
-
The role of depot fat in the hypothalamic control of food intake in the rat
-
Kennedy GC. 1953 The role of depot fat in the hypothalamic control of food intake in the rat. Proc R Soc Lond B (Biol Sci). 578-592.
-
(1953)
Proc R Soc Lond B (Biol Sci)
, pp. 578-592
-
-
Kennedy, G.C.1
-
33
-
-
13344280346
-
Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice
-
Schwartz MW, Baskin DG, Bukowski TR, et al. 1996 Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice. Diabetes. 45:531-535.
-
(1996)
Diabetes
, vol.45
, pp. 531-535
-
-
Schwartz, M.W.1
Baskin, D.G.2
Bukowski, T.R.3
-
34
-
-
0028228615
-
Neuropeptide Y and energy balance: One way ahead for the treatment of obesity?
-
Dryden S, Frankish H, Wang Q, Williams G. 1994 Neuropeptide Y and energy balance: one way ahead for the treatment of obesity? Eur J Clin Invest. 24:293-308.
-
(1994)
Eur J Clin Invest
, vol.24
, pp. 293-308
-
-
Dryden, S.1
Frankish, H.2
Wang, Q.3
Williams, G.4
-
35
-
-
0029098589
-
The role of neuropeptide Y in the anti-obesity action of the obese gene product
-
Stephens TW, Basinski M, Bristow PK, et al. 1995 The role of neuropeptide Y in the anti-obesity action of the obese gene product. Nature. 377:530-532.
-
(1995)
Nature
, vol.377
, pp. 530-532
-
-
Stephens, T.W.1
Basinski, M.2
Bristow, P.K.3
-
36
-
-
0029084089
-
3-adrenergic receptor-a cause and cure of obesity?
-
3-adrenergic receptor-a cause and cure of obesity? N Engl J Med. 333:382-383.
-
(1996)
N Engl J Med
, vol.333
, pp. 382-383
-
-
Amer, P.1
-
38
-
-
15844409555
-
Role of leptin in fat regulation
-
Collins S, Kuhn CM, Petro AE, Swick AG, Chrunyk BA, Surwit RS. 1996 Role of leptin in fat regulation. Nature. 380:677.
-
(1996)
Nature
, vol.380
, pp. 677
-
-
Collins, S.1
Kuhn, C.M.2
Petro, A.E.3
Swick, A.G.4
Chrunyk, B.A.5
Surwit, R.S.6
-
39
-
-
0029269093
-
Variation in total energy expenditure in humans
-
Goran MI. 1995 Variation in total energy expenditure in humans. Obes Res. 3(Suppl 1):59-66.
-
(1995)
Obes Res
, vol.3
, Issue.1 SUPPL.
, pp. 59-66
-
-
Goran, M.I.1
-
40
-
-
0029893211
-
Leptin concentrations in diabetic and nondiabetic Mexican-Americans
-
Haffner SM, Stern MP, Miettinen H, Wei M, Gingerich RL. 1996 Leptin concentrations in diabetic and nondiabetic Mexican-Americans. Diabetes. 45:822-824.
-
(1996)
Diabetes
, vol.45
, pp. 822-824
-
-
Haffner, S.M.1
Stern, M.P.2
Miettinen, H.3
Wei, M.4
Gingerich, R.L.5
-
41
-
-
0029112230
-
Mechanisms of enhanced insulin sensitivity in endurance trained athletes: Effects on blood flow and differential expression of Glut 4 in skeletal muscles
-
Hardin DS, Azzarelli B, Edwards J, et al. 1995 Mechanisms of enhanced insulin sensitivity in endurance trained athletes: effects on blood flow and differential expression of Glut 4 in skeletal muscles. J Clin Endocrinol Metab. 80:2437-2447.
-
(1995)
J Clin Endocrinol Metab
, vol.80
, pp. 2437-2447
-
-
Hardin, D.S.1
Azzarelli, B.2
Edwards, J.3
-
42
-
-
0030013679
-
Relationship between insulin sensitivity and plasma leptin concentrations in lean and obese males
-
Segal SR, Landt M, Klein S. 1996 Relationship between insulin sensitivity and plasma leptin concentrations in lean and obese males. Diabetes. 45:988-991.
-
(1996)
Diabetes
, vol.45
, pp. 988-991
-
-
Segal, S.R.1
Landt, M.2
Klein, S.3
-
43
-
-
0025010752
-
Glucose tolerance and hyperinsulinemia in obese women: Role of adipose tissue distribution, muscle fiber characteristics, and androgens
-
Krotkiewski M, Seidell JC, Bjorntorp P. 1990 Glucose tolerance and hyperinsulinemia in obese women: role of adipose tissue distribution, muscle fiber characteristics, and androgens. J Intern Med. 228:385-392.
-
(1990)
J Intern Med
, vol.228
, pp. 385-392
-
-
Krotkiewski, M.1
Seidell, J.C.2
Bjorntorp, P.3
-
44
-
-
0029665017
-
Acute and chronic effect of insulin on leptin production in humans
-
Kolaczynski JW, Nyce MR, Considine RV, et al. 1996 Acute and chronic effect of insulin on leptin production in humans. Diabetes. 45:699-701.
-
(1996)
Diabetes
, vol.45
, pp. 699-701
-
-
Kolaczynski, J.W.1
Nyce, M.R.2
Considine, R.V.3
-
45
-
-
0030012248
-
Plasma leptin and insulin relationships in obese and nonobese humans
-
Dagogo-Jack S, Fanelli C, Paramore D, Brothers J, Landt M. 1996 Plasma leptin and insulin relationships in obese and nonobese humans. Diabetes. 45:695-698.
-
(1996)
Diabetes
, vol.45
, pp. 695-698
-
-
Dagogo-Jack, S.1
Fanelli, C.2
Paramore, D.3
Brothers, J.4
Landt, M.5
-
46
-
-
0028821861
-
The ob gene and insulin. A relationship leading to clues to the understanding of obesity
-
Cusin I, Sainsbury A, Doyle P, Rohner-Jeanrenaud F, Jeanrenaud B. 1995 The ob gene and insulin. A relationship leading to clues to the understanding of obesity. Diabetes. 44:1467-1470.
-
(1995)
Diabetes
, vol.44
, pp. 1467-1470
-
-
Cusin, I.1
Sainsbury, A.2
Doyle, P.3
Rohner-Jeanrenaud, F.4
Jeanrenaud, B.5
-
47
-
-
0029978426
-
Nocturnal rise of leptin in lean, obese and non-insulin dependent diabetes mellitus subjects
-
Sinha MK, Ohannesian JP, Heiman ML, et al. 1996 Nocturnal rise of leptin in lean, obese and non-insulin dependent diabetes mellitus subjects. J Clin Invest. 97:1344-1347.
-
(1996)
J Clin Invest
, vol.97
, pp. 1344-1347
-
-
Sinha, M.K.1
Ohannesian, J.P.2
Heiman, M.L.3
|