Leptin suppression of insulin secretion and gene expression in human pancreatic islets: Implications for the development of adipogenic diabetes mellitus

Journal of Clinical Endocrinology and Metabolism

Volumn 84, Issue 2, 1999, Pages 670-676

  Seufert, Jochen ^a,d   Kieffer, Timothy J ^a,e   Leech, Colin A ^a   Holz, George G ^f   Moritz, Wolfgang ^a   Ricordi, Camillo ^b   Habener, Joel F ^a,c  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d UNIVERSITY HOSPITAL WÜRZBURG   (Germany)

^e UNIVERSITY OF ALBERTA   (Canada)

^f NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM ION; GLUCOSE; INSULIN; MESSENGER RNA; PROINSULIN; RECOMBINANT LEPTIN;

ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; GENE EXPRESSION; HUMAN; HUMAN TISSUE; INSULIN RELEASE; PANCREAS ISLET BETA CELL; PHENOTYPE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

CALCIUM; CARRIER PROTEINS; CELLS, CULTURED; DIABETES MELLITUS; GENE EXPRESSION; GLUCAGON; GLUCAGON-LIKE PEPTIDE 1; GLUCOSE; HUMANS; INSULIN; ISLETS OF LANGERHANS; LEPTIN; OBESITY; PEPTIDE FRAGMENTS; POTASSIUM CHANNELS; PROINSULIN; PROTEIN PRECURSORS; PROTEINS; RECEPTORS, CELL SURFACE; RNA, MESSENGER;

RODENTIA;

EID: 0033044994     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.84.2.670     Document Type: Article

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