Plasma concentration of total leptin and human lung-cancer-associated cachexia

Clinical Science

Volumn 93, Issue 3, 1997, Pages 273-277

  Simons, Jean Paul F H A ^a   Schols, Annemie M W J ^a   Campfield, L Arthur ^b   Wouters, Emiel F M ^a   Saris, Wim H ^c  

^a MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^b Hoffman La Roche Department of Metabolic Diseases   (United States)

^c MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

Cancer cachexia; Fat mass; Leptin; Pathophysiology

Indexed keywords

LEPTIN;

ADULT; AGED; ANOREXIA; APPETITE; ARTICLE; BODY COMPOSITION; BODY MASS; CACHEXIA; CLINICAL ARTICLE; ENERGY EXPENDITURE; FEEDBACK SYSTEM; HORMONE BLOOD LEVEL; HUMAN; HYPERMETABOLISM; HYPOTHALAMUS; LIPID METABOLISM; LUNG CANCER; MALE; PRIORITY JOURNAL; WEIGHT REDUCTION;

EID: 0030886382     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/cs0930273     Document Type: Article

References (37)

1. Zhang Y, Proenca R, Maffei M, Leopold L, Friedman JM. Positional cloning of the mouse obese gene and its human homologue. Nature (London) 1994; 372: 425-32. [Erratum, Nature (London) 1995; 374: 479.]
2. Tartaglia LA, Dembski M, Weng X, et al. Identification and expression cloning of a leptin receptor, OB-R. Cell 1995: 83: 1263-71.
3. Campfield LA, Smith FJ, Guisez Y, Devos R, Burn P. Recombinant mouse OB protein: evidence for a periferal signal linking adiposity and central neural networks. Science 1995: 269: 546-9.
4. Stephens TW, Basinski M, Bristow PK, et al. The rote of neuropeptide Y in the anti-obesity action of the obese gene product. Nature (London) 1995; 377: 530-2.
5. Bray GA, York DA. Hypothalamic and genetic obesity in experimental animals: an autonomic and endocrine hypothesis. Physiol Rev 1979; 59: 719-809.
6. Rohner-Jeanrenaud F. A neuroendocrine reappraisal of the dual-centre hypothesis: its implications for obesity and insulin resistance. Int J Obes Relat Metab Disord 1995; 19: 517-34.
7. Palleymounter MA, Cullen MJ, Baker MB, et al. Effects of the obese gene product on body weight regulation in ob/ob mice. Science 1995; 269: 540-3.
8. Halaas JL, Gajiwala KS, Maffei M, et al. Weight-reducing effects of the plasma protein encoded by the obese gene. Science 1995; 269: 543-6.
9. Schwartz MW, Baskin DG, Bukowski TR, et al. Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice. Diabetes 1996; 45: 531-5.
10. Dryden S, Frankish H, Wang Q, Williams G. Neuropeptide Y and energy balance: one way ahead for the treatment of obesity? Eur J Clin Invest 1994; 24: 293-308.
11. Billington CJ, Briggs JE, Grace M, Levine AS. Effects of intracerebroventricular injection of neuropeptide Y on energy metabolism. Am J Physiol 1991; 260: R321-7.
12. Considine RV, Sinha MK, Heiman ML, et al. Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N Eng J Med 1996; 334: 292-5.
13. Maffei M, Halaas J, Ravussin E, et al. Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat Med 1995; 1: 1155-61.
14. Fearon KC, Preston T. Body composition in cancer cachexia. Infusionstherapie 1990; 17 (Suppl. 3): 63-6.
15. Langstein HN, Norton JA. Mechanisms of cancer cachexia. Hematol Oncol Clin N Am 1991; 5: 103-23.
16. Tisdale MJ. Cancer cachexia. Anti-Cancer Drugs 1993; 4: 115-25.
17. Nelson KA, Walsh D, Sheehan FA. The cancer anorexia-cachexia syndrome. J Clin Oncol 1994; 12: 213-25.
18. Staal-van den Brekel AJ, Schols AM, ten Velde GP, Buurman WA, Wouters EF. Analysis of the energy balance in lung cancer patients. Cancer Res 1994: 54: 6430-3.
19. Staal-van den Brekel AJ, Dentener MA, Schols AM, Buurman WA, Wouters EF. Increased resting energy expenditure and weight loss are related to a systemic inflammatory response in lung cancer patients. J Clin Oncol 1995; 13: 2600-5.
20. De Vos P, Saladin R, Auwerx J, Staels B. Induction of ob gene expression by corticosteroids is accompanied by body weight loss and reduced food intake. J Biol Chem 1995; 270: 15958-61.
21. Wabitsch M, Jensen PB, Blum WF, et al. Insulin and cortisol promote leptin production in cultured human fat cells. Diabetes 1996; 45: 1435-8.
22. Grunfeld C, Zhao C, Fuller J, et al. Endotoxin and cytokines induce expression of leptin, the ob gene product, in hamsters. J Clin Invest 1996; 97: 2152-7.
23. Sarraf P, Frederich RC, Turner EM, et al. Multiple cytokines and acute inflammation raise mouse leptin levels: potential role in inflammatory anorexia. J Exp Med 1997; 185: 171-5.
24. Knapp ML, Al-Sheibani S, Riches PG, Hanham IW, Phillips RH. Hormonal factors associated with weight loss in patients with advanced breast cancer. Ann Clin Biochem 1991; 28: 480-6.
25. Peppler WW, Mazess RB. Total body mineral and lean body mass by dual-photon absorptiometry. Calcif Tissue Int 1981; 33: 353-9.
26. Heymsfield SB, Wang J, Heshka S, Kehayias JJ, Pierson RN. Dual-photon absorptiometry: comparison of bone mineral and soft tissue mass measurements in vivo with established methods. Am J Clin Nutr 1989: 49: 1283-9.
27. Mazess RB, Barden HS, Bisek JP, Hanson J. Dual-energy X-ray absorptiometry for total-body and regional bone-mineral and soft-tissue composition. Am J Clin Nutr 1990; 51: 1106-12.
28. Svendsen OL, Haarbo J, Hassager C, Christiansen C. Accuracy of measurements of body composition by dual-energy X-ray absorptiometry in vivo. Am J Clin Nutr 1993; 57: 605-8.
29. Weir JB. New methods for calculating metabolic rate with special reference to protein metabolism. J Physiol 1949; 109: 1-9.
30. Schols AM, Schoffelen PF, Ceulemans H, Wouters EF, Saris WH. Measurement of resting energy expenditure in patients with chronic obstructive pulmonary disease in a clinical setting. J Parenter Enteral Nutr 1992; 16: 364-8.
31. Metropolitan Life Insurance Company. New weight standards for men and women. Statist Bull Metrop Life Found 1983; 64: 1-4.
32. Warren S. The immediate causes of death in cancer. Am J Med Sci 1932; 184: 610-5.
33. DeWys WD, Begg C, Lavin PT, et al. Prognostic effect of weight loss prior to chemotherapy in cancer patients. Am J Med 1980; 69: 491-7.
34. Saladin R, De Vos P, Guerre-Millo M, et al. Transient increase in obese gene expression after food intake or insulin administration. Nature (London) 1995; 377: 527-9.
35. Rentsch J, Chiesi M. Regulation of ob gene mRNA levels in cultured adipocytes. FEBS Lett 1996; 379: 55-9.
36. McCarthy HD, McKibbin PE, Perkins AV, Linton EA, Williams G. Alterations in hypothalamic NPY and CRF in anorexic tumor-bearing rats. Am J Physiol 1993; 264: E638-43.
37. Chance WT, Balasubramaniam A, Fischer JE. Neuropeptide Y and the development of cancer anorexia. Ann Surg 1995; 221: 579-89.