-
1
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. Positional cloning of the mouse obese gene and its human homologue. Nature. 1994;372:425-432.
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
-
2
-
-
0029098589
-
The role of neuropeptide Y in the anti-obesity action of the obese gene product
-
Stephens TW, Basinski M, Bristow PK, Bue-Vallesky JM, Burgett SG, Craft L, Hale J, Hoffmann J, Hslung HM, Kriauciunas A, MacKellar W, Rosteck PR, Schoner B, Smith D, Tinsley FC, Zhang X-Y, Heiman M. The role of neuropeptide Y in the anti-obesity action of the obese gene product. Nature. 1995;377:530-532.
-
(1995)
Nature
, vol.377
, pp. 530-532
-
-
Stephens, T.W.1
Basinski, M.2
Bristow, P.K.3
Bue-Vallesky, J.M.4
Burgett, S.G.5
Craft, L.6
Hale, J.7
Hoffmann, J.8
Hslung, H.M.9
Kriauciunas, A.10
MacKellar, W.11
Rosteck, P.R.12
Schoner, B.13
Smith, D.14
Tinsley, F.C.15
Zhang, X.-Y.16
Heiman, M.17
-
3
-
-
0029804743
-
Attenuation of the obesity syndrome of ob/ob mice by loss of neuropeptide Y
-
Erickson JC, Hollopeter G, Palmiter RD. Attenuation of the obesity syndrome of ob/ob mice by loss of neuropeptide Y. Science. 1996;274: 1704-1708.
-
(1996)
Science
, vol.274
, pp. 1704-1708
-
-
Erickson, J.C.1
Hollopeter, G.2
Palmiter, R.D.3
-
4
-
-
0029739970
-
Identification of targets of leptin action in rat hypothalamus
-
Schwartz M, Seeley RJ, Campfield LA, Burn P, Baskin DG. Identification of targets of leptin action in rat hypothalamus. J Clin Invest. 1996;98:1101-1106.
-
(1996)
J Clin Invest
, vol.98
, pp. 1101-1106
-
-
Schwartz, M.1
Seeley, R.J.2
Campfield, L.A.3
Burn, P.4
Baskin, D.G.5
-
5
-
-
0030889192
-
Targeted disruption of the melanocortin-4 receptor results in obesity in mice
-
Huszar D, Lynch CA, Fairchild-Huntress V, Dunmore JH, Fang Q, Berkemeier LR, Gu W, Kesterson RA, Boston BA, Cone RD, Smith FJ, Campfield LA, Burn P, Lee F. Targeted disruption of the melanocortin-4 receptor results in obesity in mice. Cell. 1997;88:131-141.
-
(1997)
Cell
, vol.88
, pp. 131-141
-
-
Huszar, D.1
Lynch, C.A.2
Fairchild-Huntress, V.3
Dunmore, J.H.4
Fang, Q.5
Berkemeier, L.R.6
Gu, W.7
Kesterson, R.A.8
Boston, B.A.9
Cone, R.D.10
Smith, F.J.11
Campfield, L.A.12
Burn, P.13
Lee, F.14
-
6
-
-
0030614331
-
Role of melanocortinergic neurons in feeding and the agouti obesity syndrome
-
Fan W, Boston BA, Kesterson RA, Hruby VJ, Cone RD. Role of melanocortinergic neurons in feeding and the agouti obesity syndrome. Nature. 1997;385:165-168.
-
(1997)
Nature
, vol.385
, pp. 165-168
-
-
Fan, W.1
Boston, B.A.2
Kesterson, R.A.3
Hruby, V.J.4
Cone, R.D.5
-
7
-
-
0025066660
-
Preoptic area injection of corticotrophin-releasing hormone stimulates sympathetic activity
-
Egawa M, Yoshimatsu H, Bray GA. Preoptic area injection of corticotrophin-releasing hormone stimulates sympathetic activity. Am J Physiol. 1990;259:R799-R806.
-
(1990)
Am J Physiol
, vol.259
-
-
Egawa, M.1
Yoshimatsu, H.2
Bray, G.A.3
-
8
-
-
0026061245
-
Neuropeptide Y suppresses sympathetic activity to interscapular brown adipose tissue in rats
-
Egawa M, Yoshimatsu H, Bray GA. Neuropeptide Y suppresses sympathetic activity to interscapular brown adipose tissue in rats. Am J Physiol. 1991;260:R329-R334.
-
(1991)
Am J Physiol
, vol.260
-
-
Egawa, M.1
Yoshimatsu, H.2
Bray, G.A.3
-
9
-
-
0030876805
-
Receptor-mediated regional sympathetic nerve activation by leptin
-
Haynes WG, Morgan DA, Walsh SA, Mark AL, Sivitz WI. Receptor-mediated regional sympathetic nerve activation by leptin. J Clin Invest. 1997;100:270-278.
-
(1997)
J Clin Invest
, vol.100
, pp. 270-278
-
-
Haynes, W.G.1
Morgan, D.A.2
Walsh, S.A.3
Mark, A.L.4
Sivitz, W.I.5
-
10
-
-
0031455342
-
Linkage and association between the melanocortin receptors 4 and 5 genes and obesity related phenotypes in the Quebec Family Study
-
Chagnon YC, Chen WJ, Perusse L, Chagnon M, Nadeau A, Wilkison WO, Bouchard C. Linkage and association between the melanocortin receptors 4 and 5 genes and obesity related phenotypes in the Quebec Family Study. Mol Med. 1997;3:663-673.
-
(1997)
Mol Med
, vol.3
, pp. 663-673
-
-
Chagnon, Y.C.1
Chen, W.J.2
Perusse, L.3
Chagnon, M.4
Nadeau, A.5
Wilkison, W.O.6
Bouchard, C.7
-
11
-
-
0031017322
-
A major quantitative trait locus determining serum leptin levels and fat mass is located on human chromosome 2
-
Comuzzie AG, Hixson JE, Almasy L, Mitchell BD, Mahaney MC, Dyer TD, Stem MP, MacCluer JW, Blangero J. A major quantitative trait locus determining serum leptin levels and fat mass is located on human chromosome 2. Nat Genet. 1997;15:273-276.
-
(1997)
Nat Genet
, vol.15
, pp. 273-276
-
-
Comuzzie, A.G.1
Hixson, J.E.2
Almasy, L.3
Mitchell, B.D.4
Mahaney, M.C.5
Dyer, T.D.6
Stem, M.P.7
MacCluer, J.W.8
Blangero, J.9
-
12
-
-
0031838353
-
Severe early-onset obesity, adrenal insufficiency, and red hair pigmentation caused by POMC mutations in humans
-
Krude H, Biebermann H, Luck W, Horn R, Brabant G, Grüters A. Severe early-onset obesity, adrenal insufficiency, and red hair pigmentation caused by POMC mutations in humans. Nat Genet. 1998;19:155-157.
-
(1998)
Nat Genet
, vol.19
, pp. 155-157
-
-
Krude, H.1
Biebermann, H.2
Luck, W.3
Horn, R.4
Brabant, G.5
Grüters, A.6
-
13
-
-
0030663516
-
7] substituted MSH analogues for the melanocortin receptors
-
7] substituted MSH analogues for the melanocortin receptors. Peptides. 1997;18:1009-1013.
-
(1997)
Peptides
, vol.18
, pp. 1009-1013
-
-
Schiàth, H.B.1
Muceniece, R.2
Larsson, M.3
Mutulis, F.4
Szardenings, M.5
Prusis, P.6
Lindberg, G.7
Wilkberg, J.E.S.8
-
14
-
-
0028112970
-
Agouti protein is an antagonist of the melanocyte-stimulating hormone receptor
-
Lu D, Willard D, Patel IR, Kadwell S, Overton L, Kost T, Luther M, Chen W, Woychik RP, Wilkinson WO, Cone RD. Agouti protein is an antagonist of the melanocyte-stimulating hormone receptor. Nature. 1994;371: 799-802.
-
(1994)
Nature
, vol.371
, pp. 799-802
-
-
Lu, D.1
Willard, D.2
Patel, I.R.3
Kadwell, S.4
Overton, L.5
Kost, T.6
Luther, M.7
Chen, W.8
Woychik, R.P.9
Wilkinson, W.O.10
Cone, R.D.11
-
15
-
-
0030737953
-
Physiological response to long-term peripheral and central leptin infusion in lean and obese mice
-
Halaas JL, Boozer C, Blair-West J, Fidahusein N, Denton DA, Friedman JM. Physiological response to long-term peripheral and central leptin infusion in lean and obese mice. Proc Natl Acad Sci U S A. 1997;94: 8878-8883.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 8878-8883
-
-
Halaas, J.L.1
Boozer, C.2
Blair-West, J.3
Fidahusein, N.4
Denton, D.A.5
Friedman, J.M.6
-
16
-
-
0030678119
-
Independent and additive effects of central POMC and leptin pathways on murine obesity
-
Boston BA, Blaydon KM. Varnerin J. Cone RD. Independent and additive effects of central POMC and leptin pathways on murine obesity Science. 1997;278:1641-1644.
-
(1997)
Science
, vol.278
, pp. 1641-1644
-
-
Boston, B.A.1
Blaydon, K.M.2
Varnerin, J.3
Cone, R.D.4
-
17
-
-
0027953187
-
Intracerebroventricular administration of insulin produces nonuniform regional increases in sympathetic nerve activity
-
Muntzel MS, Morgan DA, Mark AL, Johnson AK. Intracerebroventricular administration of insulin produces nonuniform regional increases in sympathetic nerve activity. Am J Physiol. 1994;267:R1350-R1355.
-
(1994)
Am J Physiol
, vol.267
-
-
Muntzel, M.S.1
Morgan, D.A.2
Mark, A.L.3
Johnson, A.K.4
-
18
-
-
0027410534
-
Nonuniform regional sympathetic nerve responses to hyperinsulinemia in rats
-
Morgan DA, Balon TW, Ginsberg BH, Mark AL. Nonuniform regional sympathetic nerve responses to hyperinsulinemia in rats. Am J Physiol. 1993;264:R423-R427.
-
(1993)
Am J Physiol
, vol.264
-
-
Morgan, D.A.1
Balon, T.W.2
Ginsberg, B.H.3
Mark, A.L.4
-
19
-
-
0001895147
-
Receptors for the melanocortin peptides in the central nervous system
-
Low MJ, Simerly RB, Cone RD. Receptors for the melanocortin peptides in the central nervous system. Curr Opin Endocrinol Diabetes. 1994;1:79-88.
-
(1994)
Curr Opin Endocrinol Diabetes
, vol.1
, pp. 79-88
-
-
Low, M.J.1
Simerly, R.B.2
Cone, R.D.3
-
20
-
-
0029048408
-
Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks
-
Campfield LA, Smith FJ, Guisez Y, Devos R, Burn P. Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks. Science. 1995;269:546-549.
-
(1995)
Science
, vol.269
, pp. 546-549
-
-
Campfield, L.A.1
Smith, F.J.2
Guisez, Y.3
Devos, R.4
Burn, P.5
-
21
-
-
0029073613
-
Weight reducing effects of the plasma protein encoded by the obese gene
-
Halaas JL, Gajiwalla KS, Maffei M, Cohen SL, Chait BT, Rabinowitz D, Lallone RL, Burley SK, Friedman JM. Weight reducing effects of the plasma protein encoded by the obese gene. Science. 1995;269:543-546.
-
(1995)
Science
, vol.269
, pp. 543-546
-
-
Halaas, J.L.1
Gajiwalla, K.S.2
Maffei, M.3
Cohen, S.L.4
Chait, B.T.5
Rabinowitz, D.6
Lallone, R.L.7
Burley, S.K.8
Friedman, J.M.9
-
22
-
-
0029066265
-
Effects of the obese gene product on body weight regulation in ob/ob mice
-
Pelleymounter MA, Cullen MJ, Baker MB, Hecht R, Winters D, Boone T, Collins F. Effects of the obese gene product on body weight regulation in ob/ob mice. Science. 1995;269:540-543.
-
(1995)
Science
, vol.269
, pp. 540-543
-
-
Pelleymounter, M.A.1
Cullen, M.J.2
Baker, M.B.3
Hecht, R.4
Winters, D.5
Boone, T.6
Collins, F.7
-
23
-
-
15844409555
-
Role of leptin in fat regulation
-
Collins S, Kuhn CM, Petro AE, Swick AG, Chrunyk BA, Surwit RS. Role of leptin in fat regulation. Nature. 1996;380:677-682.
-
(1996)
Nature
, vol.380
, pp. 677-682
-
-
Collins, S.1
Kuhn, C.M.2
Petro, A.E.3
Swick, A.G.4
Chrunyk, B.A.5
Surwit, R.S.6
-
24
-
-
0031914232
-
Central infusion of melanocortin agonist MTII in rats: Assessment of c-fos expression and taste aversion
-
Thiele TE, van Dijk G, Yagaloff KA, Fisher SL, Schwartz M, Burn P, Seeley RJ. Central infusion of melanocortin agonist MTII in rats: assessment of c-Fos expression and taste aversion. Am J Phvsiol. 1998; 274:R248-R54.
-
(1998)
Am J Phvsiol
, vol.274
-
-
Thiele, T.E.1
Van Dijk, G.2
Yagaloff, K.A.3
Fisher, S.L.4
Schwartz, M.5
Burn, P.6
Seeley, R.J.7
-
25
-
-
0344447064
-
Selective antagonist for the melanocortin 4 receptor (HS014) increases food intake in free-feeding rats
-
Kask A, Rago L, Mutulis F, Pahkla R, Wikberg JES, Schiàth HB. Selective antagonist for the melanocortin 4 receptor (HS014) increases food intake in free-feeding rats. Biochem Biophys Res Commun. 1998; 245:90-93.
-
(1998)
Biochem Biophys Res Commun
, vol.245
, pp. 90-93
-
-
Kask, A.1
Rago, L.2
Mutulis, F.3
Pahkla, R.4
Wikberg, J.E.S.5
Schiàth, H.B.6
-
26
-
-
0023188329
-
Effects of preoptic microinjections of alpha-MSH on fever and normal temperature control in rabbits
-
Feng JD, Dao T, Lipton JM. Effects of preoptic microinjections of alpha-MSH on fever and normal temperature control in rabbits. Brain Res. 1987;18:473-477.
-
(1987)
Brain Res
, vol.18
, pp. 473-477
-
-
Feng, J.D.1
Dao, T.2
Lipton, J.M.3
-
27
-
-
7144242309
-
Effects of a potent melanocortin agonist on the diabetic/obese phenotype in yellow mice
-
Zemel MB, Moore JW, Moustaid N, Kim JH, Nichols JS, Blanchard SG, Parks DJ, Harris C, Lee FW, Grizzle M, James M, Wilkison WO. Effects of a potent melanocortin agonist on the diabetic/obese phenotype in yellow mice. Int J Obes. 1998;22:678-683.
-
(1998)
Int J Obes
, vol.22
, pp. 678-683
-
-
Zemel, M.B.1
Moore, J.W.2
Moustaid, N.3
Kim, J.H.4
Nichols, J.S.5
Blanchard, S.G.6
Parks, D.J.7
Harris, C.8
Lee, F.W.9
Grizzle, M.10
James, M.11
Wilkison, W.O.12
-
28
-
-
0031057818
-
Leptin is a metabolic gate for the onset of puberty in the female rat
-
Cheung C, Thornton J, Kuijper J, Weigle D, Clifton D, Steiner R. Leptin is a metabolic gate for the onset of puberty in the female rat. Endocrinology. 1997;138:4489-4493.
-
(1997)
Endocrinology
, vol.138
, pp. 4489-4493
-
-
Cheung, C.1
Thornton, J.2
Kuijper, J.3
Weigle, D.4
Clifton, D.5
Steiner, R.6
-
29
-
-
0030775971
-
Leptin increases hypothalamic proopiomelanocortin mRNA expression in the rostral arcuate nucleus
-
Schwartz MW, Seeley RJ, Woods SC, Weigle DS, Campfield LA, Burn P, Baskin DG. Leptin increases hypothalamic proopiomelanocortin mRNA expression in the rostral arcuate nucleus. Diabetes. 1997;46: 2119-2123.
-
(1997)
Diabetes
, vol.46
, pp. 2119-2123
-
-
Schwartz, M.W.1
Seeley, R.J.2
Woods, S.C.3
Weigle, D.S.4
Campfield, L.A.5
Burn, P.6
Baskin, D.G.7
-
30
-
-
0030729210
-
Regulation of hypothalamic proopiomelanocortin mRNA by leptin in ob/ob mice
-
Thornton JE, Cheung CC, Clifton DK, Steiner RA. Regulation of hypothalamic proopiomelanocortin mRNA by leptin in ob/ob mice. Endocrinology. 1997;138:5063-5066.
-
(1997)
Endocrinology
, vol.138
, pp. 5063-5066
-
-
Thornton, J.E.1
Cheung, C.C.2
Clifton, D.K.3
Steiner, R.A.4
-
31
-
-
0031443366
-
Melanocortin receptors in leptin effects
-
Letter
-
Seeley RJ, Yagaloff KA, Fisher SL, Burn P, Thiele TE, van Dijk G, Baskin DG, Schwartz MW. Melanocortin receptors in leptin effects. Nature. 1997;390:349. Letter.
-
(1997)
Nature
, vol.390
, pp. 349
-
-
Seeley, R.J.1
Yagaloff, K.A.2
Fisher, S.L.3
Burn, P.4
Thiele, T.E.5
Van Dijk, G.6
Baskin, D.G.7
Schwartz, M.W.8
-
32
-
-
0032547042
-
Satiety effect and sympathetic activation of leptin are mediated by melanocortin system
-
Satoh N, Ogawa Y, Katsura G, Numata Y, Masuzaki H, Yoshimasa Y, Nakao K. Satiety effect and sympathetic activation of leptin are mediated by melanocortin system. Neurosci Lett. 1998;249:107-110.
-
(1998)
Neurosci Lett
, vol.249
, pp. 107-110
-
-
Satoh, N.1
Ogawa, Y.2
Katsura, G.3
Numata, Y.4
Masuzaki, H.5
Yoshimasa, Y.6
Nakao, K.7
-
33
-
-
0019169389
-
Effect of chronic hypertension and sympathetic denervation on wall/lumen ratio of cerebral vessels
-
Hart MN., Heistad DD, Brody MJ. Effect of chronic hypertension and sympathetic denervation on wall/lumen ratio of cerebral vessels. Hypertension. 1980;2:419-423.
-
(1980)
Hypertension
, vol.2
, pp. 419-423
-
-
Hart, M.N.1
Heistad, D.D.2
Brody, M.J.3
-
34
-
-
0024597832
-
Sympathetic nervous system influences on the kidney: Role of hypertension
-
DiBona GF. Sympathetic nervous system influences on the kidney: role of hypertension. Am J Hypertens. 1989;2:119S-124S.
-
(1989)
Am J Hypertens
, vol.2
-
-
DiBona, G.F.1
-
35
-
-
0001244390
-
Differential effects of anesthesia on heart rate (HR), renal (RSNA), and lumbar sympathetic nerve activity (LSNA) in the rat
-
Abstract
-
Morgan DA, Thorén P, Staudt SM, Mark AL. Differential effects of anesthesia on heart rate (HR), renal (RSNA), and lumbar sympathetic nerve activity (LSNA) in the rat. FASEB J. 1988;2:A1690. Abstract.
-
(1988)
FASEB J
, vol.2
-
-
Morgan, D.A.1
Thorén, P.2
Staudt, S.M.3
Mark, A.L.4
|