-
1
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM, Positional cloning of the mouse obese gene and its human homologue. Nature 372: 425-431, 1994
-
(1994)
Nature
, vol.372
, pp. 425-431
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
-
2
-
-
0028793697
-
Leptin levels reflect body lipid content in mice: Evidence for diet-induced resistance to leptin action
-
Frederich RC, Hamann A, Anderson S, Lollman B, Lowell BB, Flier JS, Leptin levels reflect body lipid content in mice: evidence for diet-induced resistance to leptin action. Nat Med 1: 1311-1314, 1996
-
(1996)
Nat Med
, vol.1
, pp. 1311-1314
-
-
Frederich, R.C.1
Hamann, A.2
Anderson, S.3
Lollman, B.4
Lowell, B.B.5
Flier, J.S.6
-
3
-
-
13344295079
-
Serum immunoreactive leptin concentrations in normal-weight and obese humans
-
Considine RV, Sinha MK, Heiman ML, Kriauciunas A, Stephens TW, Nyce MR, Ohannesian JP, Marco CC, McKee LJ, Bauer TL, Caro JF, Serum immunoreactive leptin concentrations in normal-weight and obese humans. N Engl J Med 334: 292-295, 1996
-
(1996)
N Engl J Med
, vol.334
, pp. 292-295
-
-
Considine, R.V.1
Sinha, M.K.2
Heiman, M.L.3
Kriauciunas, A.4
Stephens, T.W.5
Nyce, M.R.6
Ohannesian, J.P.7
Marco, C.C.8
McKee, L.J.9
Bauer, T.L.10
Caro, J.F.11
-
4
-
-
85047675409
-
Radioimmunological measurement of leptin in plasma and diabetic human subjects
-
McGregor GP, Desaga JF, Ehlenz K, Fischer A, Heese F, Hegele A, Lämmer C, Peiser C, Lang RE, Radioimmunological measurement of leptin in plasma and diabetic human subjects. Endocrinology 137: 1501-1504, 1996
-
(1996)
Endocrinology
, vol.137
, pp. 1501-1504
-
-
McGregor, G.P.1
Desaga, J.F.2
Ehlenz, K.3
Fischer, A.4
Heese, F.5
Hegele, A.6
Lämmer, C.7
Peiser, C.8
Lang, R.E.9
-
5
-
-
0029050937
-
Overexpression of the obese (OB) gene in adipose tissue of human obese subjects
-
Lonnquist F, Arner P, Nordfors L, Schalling M, Overexpression of the obese (OB) gene in adipose tissue of human obese subjects. Nat Med 1: 950-953, 1995
-
(1995)
Nat Med
, vol.1
, pp. 950-953
-
-
Lonnquist, F.1
Arner, P.2
Nordfors, L.3
Schalling, M.4
-
6
-
-
0029078449
-
Regulated expression of the obese gene product (leptin) in white adipose tissue and 3T3-L1 adipocytes
-
MacDougald OA, Hwang CS, Fan H, Lane MD, Regulated expression of the obese gene product (leptin) in white adipose tissue and 3T3-L1 adipocytes. Proc Natl Acad Sci USA 92: 9034-9037, 1995
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 9034-9037
-
-
MacDougald, O.A.1
Hwang, C.S.2
Fan, H.3
Lane, M.D.4
-
7
-
-
0029924714
-
Insulin increases plasma leptin concentrations in normal subjects and patients with NIDDM
-
Malmström R, Taskinen MR, Karonen SL, Yki-Järvinen H, Insulin increases plasma leptin concentrations in normal subjects and patients with NIDDM. Diabetologia 39: 993-996, 1996
-
(1996)
Diabetologia
, vol.39
, pp. 993-996
-
-
Malmström, R.1
Taskinen, M.R.2
Karonen, S.L.3
Yki-Järvinen, H.4
-
8
-
-
0030040740
-
Regulation of ob gene mRNA levels in cultured adipocytes
-
Rentsch J, Chiesi M, Regulation of ob gene mRNA levels in cultured adipocytes. FEBS Lett 379: 55-59, 1996
-
(1996)
FEBS Lett
, vol.379
, pp. 55-59
-
-
Rentsch, J.1
Chiesi, M.2
-
9
-
-
0029977866
-
Rat adipose ob mRNA levels in states of altered circulating glucose and insulin
-
Sivitz WI, Bailey HL, Donohue P, Rat adipose ob mRNA levels in states of altered circulating glucose and insulin. Biochem Biophys Res Commun 220: 520-525, 1996
-
(1996)
Biochem Biophys Res Commun
, vol.220
, pp. 520-525
-
-
Sivitz, W.I.1
Bailey, H.L.2
Donohue, P.3
-
10
-
-
0029976448
-
Regulation of expression of ob mRNA and protein by glucocorticoids and cAMP
-
Slicker LJ, Sloop KW, Surface PL, Kriauciunas A, Valleskey JB, Stephens TW, Regulation of expression of ob mRNA and protein by glucocorticoids and cAMP. J Biol Chem 271: 5301-5304, 1996
-
(1996)
J Biol Chem
, vol.271
, pp. 5301-5304
-
-
Slicker, L.J.1
Sloop, K.W.2
Surface, P.L.3
Kriauciunas, A.4
Valleskey, J.B.5
Stephens, T.W.6
-
11
-
-
0030015246
-
3 adrenergic receptors suppresses leptin expression and mediates a leptin-independent inhibition of food intake in mice
-
3 adrenergic receptors suppresses leptin expression and mediates a leptin-independent inhibition of food intake in mice. Diabetes 45: 909-914, 1996
-
(1996)
Diabetes
, vol.45
, pp. 909-914
-
-
Mantzoros, C.S.1
Qu, D.2
Frederich, R.C.3
Susulic, V.S.4
Lowell, B.B.5
Maratos-Flier, E.6
Flier, J.S.7
-
12
-
-
0029021599
-
Induction of ob gene expression by corticosteroids is accompanied by body weight loss and reduced food intake
-
De Vos P, Saladin R, Anwerx J, Staels B, Induction of ob gene expression by corticosteroids is accompanied by body weight loss and reduced food intake. J Biol Chem 270: 15958-15961, 1995
-
(1995)
J Biol Chem
, vol.270
, pp. 15958-15961
-
-
De Vos, P.1
Saladin, R.2
Anwerx, J.3
Staels, B.4
-
13
-
-
0030455365
-
Regulation of leptin production in cultured mature white adipocytes
-
Hardie LJ, Guilhot N, Trayhurn P, Regulation of leptin production in cultured mature white adipocytes. Horm Metab Res 28: 685-690, 1996
-
(1996)
Horm Metab Res
, vol.28
, pp. 685-690
-
-
Hardie, L.J.1
Guilhot, N.2
Trayhurn, P.3
-
14
-
-
0030455364
-
Regulation of ob gene expression in rodents and humans
-
Saladin R, Staels B, Auwerx J, Briggs M, Regulation of ob gene expression in rodents and humans. Horm Metab Res 28: 638-641, 1996
-
(1996)
Horm Metab Res
, vol.28
, pp. 638-641
-
-
Saladin, R.1
Staels, B.2
Auwerx, J.3
Briggs, M.4
-
15
-
-
0029048408
-
Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks
-
Campfield LA, Smith FJ, Guisez Y, Devos R, Burn P, Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks. Science 269: 546-549, 1995
-
(1995)
Science
, vol.269
, pp. 546-549
-
-
Campfield, L.A.1
Smith, F.J.2
Guisez, Y.3
Devos, R.4
Burn, P.5
-
16
-
-
0029073613
-
Weight reducing effects of the plasma protein encoded by the obese gene
-
Halaas JL, Gajiwala KS, Maffei M, Cohen SL, Chait BT, Rabinowitz D, Lallone RL, Burley SK, Friedman JM, Weight reducing effects of the plasma protein encoded by the obese gene. Science 269: 543-546, 1995
-
(1995)
Science
, vol.269
, pp. 543-546
-
-
Halaas, J.L.1
Gajiwala, K.S.2
Maffei, M.3
Cohen, S.L.4
Chait, B.T.5
Rabinowitz, D.6
Lallone, R.L.7
Burley, S.K.8
Friedman, J.M.9
-
17
-
-
0029066265
-
Effects of the obese gene product on body weight regulation in ob/ob mice
-
Pelleymounter MA, Cullen MJ, Baker MB, Hecht R, Winters D, Boone T, Collins F, Effects of the obese gene product on body weight regulation in ob/ob mice. Science 269: 541-543, 1995
-
(1995)
Science
, vol.269
, pp. 541-543
-
-
Pelleymounter, M.A.1
Cullen, M.J.2
Baker, M.B.3
Hecht, R.4
Winters, D.5
Boone, T.6
Collins, F.7
-
18
-
-
0007500186
-
Intraventricular leptin reduces food intake and body weight of lean rats but not obese Zucker rats
-
Seeley RJ, van Dijk G, Campfield LA, Smith FJ, Bum P, Nelligan JA, Bell SM, Baskin DG, Woods SC, Schwartz MW, Intraventricular leptin reduces food intake and body weight of lean rats but not obese Zucker rats. Horm Metab Res 28: 664-668, 1996
-
(1996)
Horm Metab Res
, vol.28
, pp. 664-668
-
-
Seeley, R.J.1
Van Dijk, G.2
Campfield, L.A.3
Smith, F.J.4
Bum, P.5
Nelligan, J.A.6
Bell, S.M.7
Baskin, D.G.8
Woods, S.C.9
Schwartz, M.W.10
-
19
-
-
0029962467
-
Correction of obesity and diabetes in genetically obese mice by leptin gene therapy
-
Muzzin P, Eisensmith RC, Copeland KC, Woo SLC, Correction of obesity and diabetes in genetically obese mice by leptin gene therapy. Proc Natl Acad Sci USA 93: 14804-14808, 1996
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 14804-14808
-
-
Muzzin, P.1
Eisensmith, R.C.2
Copeland, K.C.3
Woo, S.L.C.4
-
20
-
-
13344280346
-
Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice
-
Schwartz MW, Baskin DG, Bukowski TR, Kuijper JL, Foster D, Lasser G, Prunkard DE, Porte D Jr, Woods SC, Seeley RJ, Weigle DS, Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice. Diabetes 45: 531-535, 1996
-
(1996)
Diabetes
, vol.45
, pp. 531-535
-
-
Schwartz, M.W.1
Baskin, D.G.2
Bukowski, T.R.3
Kuijper, J.L.4
Foster, D.5
Lasser, G.6
Prunkard, D.E.7
Porte Jr., D.8
Woods, S.C.9
Seeley, R.J.10
Weigle, D.S.11
-
21
-
-
2442654859
-
Identification and expression cloning of a leptin receptor, OB-R
-
Tartaglia LA, Dembski M, Weng X, Deng N, Culpepper J, Devos R, Richards GJ, Campfield LA, Clark FT, Deeds J, Muir C, Sanker S, Moriarty A, Moore KJ, Smutko JS, Mays GG, Woolf EA, Monroe CA, Tepper RI, Identification and expression cloning of a leptin receptor, OB-R. Cell 83: 1263-1271, 1995
-
(1995)
Cell
, vol.83
, pp. 1263-1271
-
-
Tartaglia, L.A.1
Dembski, M.2
Weng, X.3
Deng, N.4
Culpepper, J.5
Devos, R.6
Richards, G.J.7
Campfield, L.A.8
Clark, F.T.9
Deeds, J.10
Muir, C.11
Sanker, S.12
Moriarty, A.13
Moore, K.J.14
Smutko, J.S.15
Mays, G.G.16
Woolf, E.A.17
Monroe, C.A.18
Tepper, R.I.19
-
23
-
-
0031470122
-
Leptin: A potent inhibitor of insulin secretion
-
in press
-
Fehmann HC, Peiser C, Bode HP, Stamm M, Staats P, Hedetoft C, Lang RE, Göke B, Leptin: a potent inhibitor of insulin secretion. Peptides (in press)
-
Peptides
-
-
Fehmann, H.C.1
Peiser, C.2
Bode, H.P.3
Stamm, M.4
Staats, P.5
Hedetoft, C.6
Lang, R.E.7
Göke, B.8
-
24
-
-
0030965884
-
Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion
-
Emilsson V, Liu YL, Cawthorne MA, Morton NM, Davenport M, Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion. Diabetes 46: 313-316, 1997
-
(1997)
Diabetes
, vol.46
, pp. 313-316
-
-
Emilsson, V.1
Liu, Y.L.2
Cawthorne, M.A.3
Morton, N.M.4
Davenport, M.5
-
25
-
-
0023912253
-
Automated method for isolation of human pancreatic islets
-
Ricordi C, Lacy PE, Finke E, Olack B, Scharp DW, Automated method for isolation of human pancreatic islets Diabetes 37: 413-420, 1988
-
(1988)
Diabetes
, vol.37
, pp. 413-420
-
-
Ricordi, C.1
Lacy, P.E.2
Finke, E.3
Olack, B.4
Scharp, D.W.5
-
26
-
-
0024532674
-
Large-scale purification of human islets utilizing albumin gradient on IBM 2991 cell seperator
-
Lak SP, Bassett PD, Larkins A, Revell J, Walczak K, Chamberlain J, Rumford GW, London NJM, Veitch PS, Bell RPF, James RFL, Large-scale purification of human islets utilizing albumin gradient on IBM 2991 cell seperator. Diabetes 38 [Suppl 1]: 143-145, 1989
-
(1989)
Diabetes
, vol.38
, Issue.1 SUPPL.
, pp. 143-145
-
-
Lak, S.P.1
Bassett, P.D.2
Larkins, A.3
Revell, J.4
Walczak, K.5
Chamberlain, J.6
Rumford, G.W.7
London, N.J.M.8
Veitch, P.S.9
Bell, R.P.F.10
James, R.F.L.11
-
27
-
-
0029616629
-
Islet isolation from the pancreas of large mammals and humans: 10 years' experience
-
Brandhorst D, Brandhorst H, Hering BJ, Federlin K, Bretzel RG, Islet isolation from the pancreas of large mammals and humans: 10 years' experience. Exp Clin Endocrinol 103: 3-14, 1995
-
(1995)
Exp Clin Endocrinol
, vol.103
, pp. 3-14
-
-
Brandhorst, D.1
Brandhorst, H.2
Hering, B.J.3
Federlin, K.4
Bretzel, R.G.5
-
28
-
-
0018824237
-
Islet transplantation in experimental diabetes of the rat. Cryopreservation of rat and human islets. Preliminary results
-
Bretzel RG, Schneider J, Dobroschke J, Schwemmle K, Pfeiffer EF, Federlin K, Islet transplantation in experimental diabetes of the rat. Cryopreservation of rat and human islets. Preliminary results. Horm Metab Res 12: 274-275, 1980
-
(1980)
Horm Metab Res
, vol.12
, pp. 274-275
-
-
Bretzel, R.G.1
Schneider, J.2
Dobroschke, J.3
Schwemmle, K.4
Pfeiffer, E.F.5
Federlin, K.6
-
29
-
-
0028265613
-
Clinical islet transplantation: Guidelines for islet quality control
-
Bretzel RG, Alejandro R, Hering BJ, van Suylichem PT, Ricordi C, Clinical islet transplantation: guidelines for islet quality control. Transplant Proc 26: 388-392, 1994
-
(1994)
Transplant Proc
, vol.26
, pp. 388-392
-
-
Bretzel, R.G.1
Alejandro, R.2
Hering, B.J.3
Van Suylichem, P.T.4
Ricordi, C.5
-
30
-
-
0029860791
-
Modulation of insulin activities by leptin
-
Cohen B, Novick D, Rubinstein M, Modulation of insulin activities by leptin. Science 274: 1185-1188, 1996
-
(1996)
Science
, vol.274
, pp. 1185-1188
-
-
Cohen, B.1
Novick, D.2
Rubinstein, M.3
-
31
-
-
0029043139
-
Cell and molecular biology of the incretin hormones glucagon-like peptide-I and glucose-dependent insulin releasing polypeptide
-
Fehmann HC, Göke R, Göke B, Cell and molecular biology of the incretin hormones glucagon-like peptide-I and glucose-dependent insulin releasing polypeptide. Endocr Rev 16: 390-410, 1995
-
(1995)
Endocr Rev
, vol.16
, pp. 390-410
-
-
Fehmann, H.C.1
Göke, R.2
Göke, B.3
-
32
-
-
0029028687
-
The effects of glucagon-like peptide-I (GLP-I) on hormone secretion from isolated human pancreatic islets
-
Fehmann HC, Hering BJ, Wolf MJ, Brandhorst H, Brandhorst D, Bretzel RG, Federlin K, Göke B, The effects of glucagon-like peptide-I (GLP-I) on hormone secretion from isolated human pancreatic islets. Pancreas 11: 196-200, 1995
-
(1995)
Pancreas
, vol.11
, pp. 196-200
-
-
Fehmann, H.C.1
Hering, B.J.2
Wolf, M.J.3
Brandhorst, H.4
Brandhorst, D.5
Bretzel, R.G.6
Federlin, K.7
Göke, B.8
-
33
-
-
0030013679
-
Relationship between insulin sensitivity and plasma leptin concentration in lean and obese men
-
Segal KR, Landt M, Klein S, Relationship between insulin sensitivity and plasma leptin concentration in lean and obese men. Diabetes 45: 988-991, 1996
-
(1996)
Diabetes
, vol.45
, pp. 988-991
-
-
Segal, K.R.1
Landt, M.2
Klein, S.3
-
34
-
-
0029020677
-
Evidence against either a premature stop codon or the absence on obese gene mRNA in human obesity
-
Considine RV, Considine EL, Williams CJ, Nyce MR, Magosin SA, Bauer TL, Rosato EL, Colbert J, Caro JF, Evidence against either a premature stop codon or the absence on obese gene mRNA in human obesity. J Clin Invest 95: 2986-2988, 1995
-
(1995)
J Clin Invest
, vol.95
, pp. 2986-2988
-
-
Considine, R.V.1
Considine, E.L.2
Williams, C.J.3
Nyce, M.R.4
Magosin, S.A.5
Bauer, T.L.6
Rosato, E.L.7
Colbert, J.8
Caro, J.F.9
-
35
-
-
0030015417
-
Defective STAT signaling by the leptin receptor in diabetic mice
-
Ghilardi N, Ziegler S, Wiestner A, Stoffel R, Heim MH, Skoda RC, Defective STAT signaling by the leptin receptor in diabetic mice. Proc Natl Acad Sci USA 93: 6231-6235, 1996
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 6231-6235
-
-
Ghilardi, N.1
Ziegler, S.2
Wiestner, A.3
Stoffel, R.4
Heim, M.H.5
Skoda, R.C.6
|