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Volumn 12, Issue 1, 1998, Pages 57-65

Leptin regulates proinflammatory immune responses

Author keywords

Cytokine; Lipopolysaccharide; Macrophage; Obesity; Phagocytic function; TNF

Indexed keywords

LEPTIN; LEPTIN RECEPTOR;

EID: 0031965266     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fsb2fasebj.12.1.57     Document Type: Article
Times cited : (1119)

References (37)
  • 1
    • 0029048408 scopus 로고
    • Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks
    • Campfield, L. A., Smith, F. J., Buisez, Y., Devos, R., and Burn, P. (1995) Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks. Science 269, 546-549
    • (1995) Science , vol.269 , pp. 546-549
    • Campfield, L.A.1    Smith, F.J.2    Buisez, Y.3    Devos, R.4    Burn, P.5
  • 5
    • 0028968879 scopus 로고
    • The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase
    • Kern, P. A., Saghizadeh, M., Ong, J. M., Bosch, R. J., Deem, R., and Simsolo, R. B. (1995) The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase. J. Clin. Invest. 95, 2111-2119
    • (1995) J. Clin. Invest. , vol.95 , pp. 2111-2119
    • Kern, P.A.1    Saghizadeh, M.2    Ong, J.M.3    Bosch, R.J.4    Deem, R.5    Simsolo, R.B.6
  • 6
    • 0029847504 scopus 로고    scopus 로고
    • Uncoupling of obesity from insulin resistance through a targeted mutation in aP2, the adipocyte fatty acid binding protein
    • Hotamisligil, G. S., Peraldi, P., Budavari, A., Ellis, R., White, M. F., and Spiegelman, B. M. (1996) Uncoupling of obesity from insulin resistance through a targeted mutation in aP2, the adipocyte fatty acid binding protein. Science 274, 1377-1379
    • (1996) Science , vol.274 , pp. 1377-1379
    • Hotamisligil, G.S.1    Peraldi, P.2    Budavari, A.3    Ellis, R.4    White, M.F.5    Spiegelman, B.M.6
  • 7
    • 0029970507 scopus 로고    scopus 로고
    • Body weight, cardiovascular risk factors, and coronary mortality. 15-year follow-up of middle-aged men and women in eastern Finland
    • Jouislahti, P., Tuomilehto, J., Vartiainen, E., Pekkanen, J., and Puska, P. (1996) Body weight, cardiovascular risk factors, and coronary mortality. 15-year follow-up of middle-aged men and women in eastern Finland. Circulation 93, 1372-1397
    • (1996) Circulation , vol.93 , pp. 1372-1397
    • Jouislahti, P.1    Tuomilehto, J.2    Vartiainen, E.3    Pekkanen, J.4    Puska, P.5
  • 8
    • 0029966988 scopus 로고    scopus 로고
    • The 25-year health care costs of women who remain overweight after 40 years of age
    • Gorsky, R. D., Pamuk, E., Williamson, D. F., Shaffer, P. A., and Koplan, J. P. (1996) The 25-year health care costs of women who remain overweight after 40 years of age. Am. J. Prev. Med. 12, 388-394
    • (1996) Am. J. Prev. Med. , vol.12 , pp. 388-394
    • Gorsky, R.D.1    Pamuk, E.2    Williamson, D.F.3    Shaffer, P.A.4    Koplan, J.P.5
  • 9
    • 0029961095 scopus 로고    scopus 로고
    • Overweight, underweight, and mortality. A prospective study of 48,287 men and women
    • Seidell, J. C., Verschuren, W. M., van Leer, E. M., and Kromhout, D. (1996) Overweight, underweight, and mortality. A prospective study of 48,287 men and women. Arch. Int. Med. 156, 958-963
    • (1996) Arch. Int. Med. , vol.156 , pp. 958-963
    • Seidell, J.C.1    Verschuren, W.M.2    Van Leer, E.M.3    Kromhout, D.4
  • 10
    • 0001513966 scopus 로고    scopus 로고
    • Obesity increases sensitivity to endotoxin liver injury: Implications for the pathogenesis of steatohepatitis
    • Yang, S. Q., Lin, H. Z., Lane, M. D., Clemens, M., and Diehl, A. M. (1997) Obesity increases sensitivity to endotoxin liver injury: Implications for the pathogenesis of steatohepatitis. Proc. Natl. Acad. Sci. USA 94, 2557-2562
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 2557-2562
    • Yang, S.Q.1    Lin, H.Z.2    Lane, M.D.3    Clemens, M.4    Diehl, A.M.5
  • 11
    • 0030061922 scopus 로고    scopus 로고
    • IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha-and obesity-induced insulin resistance
    • Hotamisligil, G. S., Peraldi, P., Budavari, A., Ellis, R., White, M. F., and Spiegelman, B. M. (1996) IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha-and obesity-induced insulin resistance. Science 271, 665-668
    • (1996) Science , vol.271 , pp. 665-668
    • Hotamisligil, G.S.1    Peraldi, P.2    Budavari, A.3    Ellis, R.4    White, M.F.5    Spiegelman, B.M.6
  • 12
    • 0027333425 scopus 로고
    • Tumor necrosis factor, other cytokines and disease
    • Tracey, K. J., and Cerami, A. (1993) Tumor necrosis factor, other cytokines and disease. Annu. Rev. Cell Biol. 9, 317-343
    • (1993) Annu. Rev. Cell Biol. , vol.9 , pp. 317-343
    • Tracey, K.J.1    Cerami, A.2
  • 13
    • 0026717674 scopus 로고
    • The pathophysiology of tumor necrosis factor
    • Vassalli, P. (1992) The pathophysiology of tumor necrosis factor. Annu. Rev. Immunol. 10, 411-452
    • (1992) Annu. Rev. Immunol. , vol.10 , pp. 411-452
    • Vassalli, P.1
  • 14
    • 0028965644 scopus 로고
    • Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin
    • Ulevitch, R. J., and Tobias, P. S. (1995) Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin. Annu. Rev. Immunol. 13, 437-457
    • (1995) Annu. Rev. Immunol. , vol.13 , pp. 437-457
    • Ulevitch, R.J.1    Tobias, P.S.2
  • 15
    • 0019215252 scopus 로고
    • Current concepts. the macrophage as an effector cell
    • Nathan, C. F., Murray, H. W., and Cohen, Z. A. (1980) Current concepts. The macrophage as an effector cell. N. Engl. J. Med. 303, 622-626
    • (1980) N. Engl. J. Med. , vol.303 , pp. 622-626
    • Nathan, C.F.1    Murray, H.W.2    Cohen, Z.A.3
  • 18
    • 0000370303 scopus 로고
    • Identification of a common nucleotide-sequence in the 3′-untranslated region of mRNA molecules specifying inflammatory mediators
    • Caput, D., Beutler, B., Hartog, K., Thayer, R., Brown-Shimer, S., and Cerami, A. (1986) Identification of a common nucleotide-sequence in the 3′-untranslated region of mRNA molecules specifying inflammatory mediators. Proc. Natl. Acad. Sci. USA 83, 1670-1674
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 1670-1674
    • Caput, D.1    Beutler, B.2    Hartog, K.3    Thayer, R.4    Brown-Shimer, S.5    Cerami, A.6
  • 19
    • 0028987562 scopus 로고
    • Interleukin-12 is required for interferon-gamma production and lethality in lipopolysaccharide-induced shock in mice
    • Wysocka, M., Kubin, M., Vieira, L. Q., Ozmen, L., Garotta, G., Scott, P., and Trinchieri, G. (1995) Interleukin-12 is required for interferon-gamma production and lethality in lipopolysaccharide-induced shock in mice. Eur. J. Immunol. 25, 672-676
    • (1995) Eur. J. Immunol. , vol.25 , pp. 672-676
    • Wysocka, M.1    Kubin, M.2    Vieira, L.Q.3    Ozmen, L.4    Garotta, G.5    Scott, P.6    Trinchieri, G.7
  • 20
    • 0027242026 scopus 로고
    • Hyaluronate activation of CD44 induces insulin-like growth factor-1 expression by a TNF-alpha dependent mechanism in murine macrophages
    • Noble, P. W., Lake, F. R., Henson, P. M., and Riches, D. W. H. (1993) Hyaluronate activation of CD44 induces insulin-like growth factor-1 expression by a TNF-alpha dependent mechanism in murine macrophages. J. Clin. Invest. 91, 2368-2377
    • (1993) J. Clin. Invest. , vol.91 , pp. 2368-2377
    • Noble, P.W.1    Lake, F.R.2    Henson, P.M.3    Riches, D.W.H.4
  • 21
    • 0029907839 scopus 로고    scopus 로고
    • Role of reactive oxygen metabolites in murine peritoneal macrophage phagocytosis and phagocytic killing
    • Takao, S., Smith, E. H., Wang, D., Chan, C. K., Bulkley, G. B., and Klein, A. S. (1996) Role of reactive oxygen metabolites in murine peritoneal macrophage phagocytosis and phagocytic killing. Am. J. Physiol. 271, C1278-C1285
    • (1996) Am. J. Physiol. , vol.271
    • Takao, S.1    Smith, E.H.2    Wang, D.3    Chan, C.K.4    Bulkley, G.B.5    Klein, A.S.6
  • 22
    • 0028055238 scopus 로고
    • Quantitative discrimination of hepatic reticuloendothelial clearance and phagocytic killing
    • Klein, A., Zhadkewich, Margolick, J., Winkelstin, J., and Bulkley, G. (1994) Quantitative discrimination of hepatic reticuloendothelial clearance and phagocytic killing. J. Leukoc. Biol. 55, 248-252
    • (1994) J. Leukoc. Biol. , vol.55 , pp. 248-252
    • Klein, A.1    Zhadkewich2    Margolick, J.3    Winkelstin, J.4    Bulkley, G.5
  • 23
    • 0023277545 scopus 로고
    • Single step method for RNA isolation by acid guanidine thiocyanate-phenol-chloroform extraction
    • Chomczynski, P., and Sacchi, N. (1987) Single step method for RNA isolation by acid guanidine thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162, 156-161
    • (1987) Anal. Biochem. , vol.162 , pp. 156-161
    • Chomczynski, P.1    Sacchi, N.2
  • 26
    • 0030028959 scopus 로고    scopus 로고
    • Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (leptin) receptor
    • Chua, S. C., Jr., Chung, W. K., Wu-Peng, X. S., Zhang, Y., Liu, S. M., Tartaglia, L., and Leibel, R. L. (1996) Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (leptin) receptor. Science 271, 994-996
    • (1996) Science , vol.271 , pp. 994-996
    • Chua Jr., S.C.1    Chung, W.K.2    Wu-Peng, X.S.3    Zhang, Y.4    Liu, S.M.5    Tartaglia, L.6    Leibel, R.L.7
  • 28
    • 0031014413 scopus 로고    scopus 로고
    • Early onset of reproductive function in normal female mice treated with leptin
    • Chehab, F. F., Mounzih, K., Lu, R., and Lim, M. E. (1997) Early onset of reproductive function in normal female mice treated with leptin. Science 275, 88-90
    • (1997) Science , vol.275 , pp. 88-90
    • Chehab, F.F.1    Mounzih, K.2    Lu, R.3    Lim, M.E.4
  • 31
    • 0028970060 scopus 로고
    • Interleukin-12: A proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity
    • Trienchieri, G. (1995) Interleukin-12: A proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu. Rev. Immunol. 13, 251-276
    • (1995) Annu. Rev. Immunol. , vol.13 , pp. 251-276
    • Trienchieri, G.1
  • 32
    • 0027400726 scopus 로고
    • Multiple defects of immune cell fucntion in mice with disrupted interferon-gamma genes
    • Dalton, D. K., Pitts-Meek, S., Keshav, S., Figari, I. S., Bradley, A., and Stewart, T. A. (1993) Multiple defects of immune cell fucntion in mice with disrupted interferon-gamma genes. Science 259, 1739-1742
    • (1993) Science , vol.259 , pp. 1739-1742
    • Dalton, D.K.1    Pitts-Meek, S.2    Keshav, S.3    Figari, I.S.4    Bradley, A.5    Stewart, T.A.6
  • 35
    • 0029930468 scopus 로고    scopus 로고
    • Immune responsiveness in a rat model for type II diabetes (Zucker rat, fa/fa): Susceptibility to Candida albicans infection and leucocyte function
    • Plotkin, B. J., Paulson, D., Chelich, A., Jurak, D., Cole, J., Kasimos, J., Burdick, J. R., and Casteel, N. (1996) Immune responsiveness in a rat model for type II diabetes (Zucker rat, fa/fa): susceptibility to Candida albicans infection and leucocyte function. J. Med. Microbiol. 44, 277-283
    • (1996) J. Med. Microbiol. , vol.44 , pp. 277-283
    • Plotkin, B.J.1    Paulson, D.2    Chelich, A.3    Jurak, D.4    Cole, J.5    Kasimos, J.6    Burdick, J.R.7    Casteel, N.8
  • 37
    • 0026013816 scopus 로고
    • Lymphocytes play the music but macrophages call the tune
    • Solbach, W. H., and Rollinghoff, M. (1991) Lymphocytes play the music but macrophages call the tune. Immunol. Today 12, 4-6
    • (1991) Immunol. Today , vol.12 , pp. 4-6
    • Solbach, W.H.1    Rollinghoff, M.2


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