Congenital leptin deficiency is associated with severe early-onset obesity in humans

Nature

Volumn 387, Issue 6636, 1997, Pages 903-908

  Montague, Carl T ^a   Farooqi, I Sadaf ^a,b   Whitehead, Jonathan P ^a,b   Soos, Maria A ^a,b   Rau, Harald ^a,b   Wareham, Nicholas J ^b   Sewter, Ciaran P ^a,b   Digby, Janet E ^a,b   Mohammed, Shehla N ^c   Hurst, Jane A ^d   Cheetham, Christopher H ^f   Earley, Alison R ^f   Barnett, Anthony H ^e   Prins, Johannes B ^a,b   O'Rahilly, Stephen ^a,b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c GUY S HOSPITAL   (United Kingdom)

^d CHURCHILL HOSPITAL   (United Kingdom)

^e UNIVERSITY DEPARTMENT OF MEDICINE   (United Kingdom)

^f WYCOMBE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

LEPTIN;

ADIPOSE TISSUE; ARTICLE; CASE REPORT; CONSANGUINITY; ENERGY BALANCE; FEMALE; FRAMESHIFT MUTATION; GENETIC LINKAGE; HUMAN; MALE; OBESITY; ONSET AGE; PATHOGENESIS; PEDIGREE ANALYSIS; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN LOCALIZATION;

ADULT; AGE OF ONSET; ANIMALS; BODY COMPOSITION; CHILD; CHILD, PRESCHOOL; CHO CELLS; CONSANGUINITY; CRICETINAE; FEMALE; FRAMESHIFT MUTATION; HOMOZYGOTE; HUMANS; LEPTIN; MALE; METABOLISM, INBORN ERRORS; MICE; MICE, OBESE; MOLECULAR SEQUENCE DATA; OBESITY; PEDIGREE; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; PROTEINS; SEQUENCE ANALYSIS, DNA; TRANSFECTION;

EID: 0030878110     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/43185     Document Type: Article

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