Leptin and reproduction

Reviews of Reproduction

Volumn 4, Issue 1, 1999, Pages 48-55

  Clarke, Lain J ^a   Henry, B A ^a  

^a HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

LEPTIN; LEPTIN RECEPTOR;

FEMALE; HUMAN; HYPOTHALAMUS HYPOPHYSIS GONAD SYSTEM; NONHUMAN; PLACENTA; PREGNANCY; PRIORITY JOURNAL; PUBERTY; REPRODUCTION; REVIEW; RODENT; SEXUAL MATURATION;

EID: 20644445189     PISSN: 13596004     EISSN: None     Source Type: Journal    
DOI: 10.1530/ror.0.0040048     Document Type: Review

References (72)

1. Adam CL, Findlay PA, Kyle CE and Young P (1998) Effect of restricted nutrition on timing of puberty in female Soay sheep Journal of Reproduction and Fertility 112 31–37
2. Adashi EY (1995) Ovary as a site of growth hormone reception and action. In The Somatotrophic Axis and the Reproductive Process in Health and Disease pp 175–182 Eds EY Adashi and MO Thorner. Serono Symposia USA. Springer Verlag, New York
3. Ahima RS, Prabakaran D, Mantzoros C, Qu D, Lowell B, Maratos-Flier E and Flier JS (1996) Role of leptin in the neuroendocrine response to fasting Nature (London) 382 250–252
4. Arslanian S and Suprasongsin C (1997) Testosterone treatment in adolescents with delayed puberty: changes in body composition, protein, fat, and glucose metabolism Journal of Clinical Endocrinology and Metabolism 82 3213–3220
5. Barash IA, Cheung CC, Weigle DS, Ren H, Kabigting EB, Kuijper JL, Clifton DK, Steiner RA (1996) Leptin is a metabolic signal to the reproductive system Endocrinology 137 3144–3147
6. Barker-Gibb ML and Clarke IJ (1996) Increased galanin and neuropeptide Y immunoreactivity within the hypothalamus of ovariectomized ewes following a prolonged period of reduced body weight correlates with changes in plasma growth hormone levels but not gonadotropin levels Neuroendocrinology 64 194–207
7. Barker-Gibb ML, Scott CJ, Boublik JH and Clarke IJ (1995) The role of neuropeptide Y (NPY) in the control of LH secretion in the ewe with respect to season, NPY receptor subtype and the site of action in the hypothalamus Journal of Endocrinology 147 565–579
8. Baskin DG, Norwood BJ, Schwartz MW and Koerker DJ (1995) Estradiol inhibits the increase of hypothalamic neuropeptide Y messenger ribonucleic acid expression induced by weight loss in ovariectomized rats Endocrinology 136 5547–5554
9. Bennett PA, Lindell K, Karlsson C, Robinson ICAF, Carlsson LMS and Carlsson B (1998) Differential expression and regulation of leptin receptor isoforms in the rat brain: effects of fasting and oestrogen Neuroendocrinology 67 29–36
10. Bittencourt JC, Presse F, Arias C, Peto C, Vaughn J, Nahon JL, Vale W, Sawchenko PE (1992) The melanin-concentrating hormone system of the rat brain: an immuno-and hybridisation histochemical characterisation Journal of Comparative Neurology 319 218–245
11. Bronson FH (1985) Mammalian reproduction: an ecological perspective Biology of Reproduction 32 1–26
12. Cameron JL and Nobisch C (1991) Suppression of pulsatile luteinizing hormone and testosterone secretion during short term food restriction in the adult male rhesus monkey (Macaca mulatta) Endocrinology 128 1532–1540
13. Campfield LA, Smith FJ, Guisez Y, Devos R and Burn P (1995) Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks Science 269 546–549
14. Carro E, Pinilla L, Seoane LM, Considine RV, Aguilar E, Casanueva FF and Dieguez C (1997) Influence of endogenous leptin tone on the estrous cycle and luteinizing hormone pulsatility in female rats Neuroendocrinology 66 375–377
15. Chehab F, Lim ME and Lu R (1996) Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin. Nature Genetics 12 318–320
16. Chehab FF, Mounzih K, Lu R and Lim ME (1997) Early onset of reproductive function in normal female mice treated with leptin Science 275 88–90
17. Chen M-D, O’Byrne KT, Chiappini J and Knobil E (1992) Hypoglycemic ‘stress’ and gonadotropin-releasing hormone pulse generator activity in the rhesus monkey: role of the ovary Neuroendocrinology 56 666–673
18. Cheung CC, Clifton DK, Steiner RA (1997a) Proopiomelanocortin neurons are direct targets for leptin in the hypothalamus Endocrinology 138 4489–4492
19. Cheung CC, Thornton JE, Kuijper JL, Weigle DS, Clifton DK, Steiner RA (1997b) Leptin is a metabolic gate for the onset of puberty in the female rat Endocrinology 138 855–858
20. Clarke IJ, Horton RJE and Doughton BW (1990) An investigation of the mechanism by which insulin-induced hypoglycemia decreases LH secretion in ovariectomized ewes Endocrinology 127 1470–1476
21. Clayton PE, Gill MS, Hall CM, Tillmann V, Whatmore AJ and Price DA (1997) Serum leptin throughout childhood and adolescence Clinical Endocrinology 46 727–733
22. Considine RV, Sinha MK, Heiman ML et al. (1996) The protein product of Ob gene is elevated in human obesity: effect of weight loss fasting and feeding New England Journal of Medicine 334 292–295
23. Dagogo-Jack S, Fanelli C, Paramore D, Brothers J and Landt M (1996) Plasma leptin and insulin relationships in obese and non-obese humans Diabetes 45 695–698
24. Dyer CJ, Simmons JM, Matteri RL and Keisler DH (1997) Leptin receptor mRNA is expressed in ewe anterior pituitary and adipose tissues and is differentially expressed in hypothalamic regions of well-fed and feed-restricted ewes Domestic Animal Endocrinology 14 119–128
25. Forbes JM (1982) Effects of lighting patterns on growth, lactation and food intake of sheep, cattle and deer Livestock Production Science 9 361–374
26. Foster DL, Bucholtz DC and Herbosa CG (1995) Metabolic signals and the timing of puberty in sheep. In The Neurobiology of Puberty pp 243–257 Eds TM Plant and PA Lee. Journal of Endocrinology, Bristol
27. Goldstone AP, Mercer JG, Gunn I et al. (1997) Leptin interacts with glucagon-like peptide-1 neurons to reduce food intake and body weight in rodents FEBS Letters 415 134–138
28. Gonzalez MI, Baker BI and Wilson CA (1997) Stimulatory effect of melanin-concentrating hormone on luteinising hormone release Neuroendocrinology 66 254–262
29. Gruaz NM, Lalaoui M, Pierroz DD, Englaro P, Sizonenko PC, Blum WF and Aubert ML (1998) Chronic administration of leptin into the lateral ventricle induces sexual maturation in severely food-restricted female rats Journal of Neuroendocrinology 10 627–633
30. Hakansson M-L, Brown H, Ghilardi N, Skoda RC and Meister B (1998) Leptin receptor immunoreactivity in chemically defined target neurons of the hypothalamus Journal of Neuroscience 18 559–572
31. Halaas JL, Gajiwala KS, Maffei M, Cohen SL, Chait BT, Rabinowitz D, Lallone RL, Burley SK and Friedman JM (1995) Weight-reducing effects of the plasma protein encoded by the obese gene Science 269 543–546
32. Hardie L, Trayhurn P, Abramovich D and Fowler P (1997) Circulating leptin in women: a longitudinal study in the menstrual cycle and during pregnancy Clinical Endocrinology 47 101–106
33. Harris RBS, Zhou J, Redmann SM, Smagin GN, Smith SR, Rodgers E and Zachwieja JJ (1998) A leptin dose–response study in obese (ob/ob) and lean (=/?) mice Endocrinology 139 8–19
34. Henry B, Goding J, Alexander W, Tilbrook A, Canny B, Dunshea F and Clarke IJ (1998) Central administration of leptin to ovariectomised ewes inhibits food intake without affecting the secretion of hormones from the pituitary gland: evidence for a dissociation of effects on appetite and neuroendocrine function Endocrinology
35. Hoggard N, Mercer JG, Rayner DV, Moar K Trayhurn P and Williams LM (1997) Localization of leptin receptor mRNA splice variants in murine peripheral tissues by RT–PCR and in situ hybridisation Biochemical and Biophysical Research Communications 232 383–387
36. Kalra SP (1993) Mandatory neuropeptide-steroid signalling for the pre-ovulatory luteinizing hormone-releasing hormone discharge Endocrine Reviews 14 507–538
37. Karlsson C, Lindell K, Svensson E, Bergh C, Lind P, Billig H, Carlsson LMS and Carlsson B (1997). Expression of functional leptin receptors in the human ovary Journal of Clinical Endocrinology and Metabolism 82 4144–4148
38. Kawai M, Yamaguchi M, Murukami T, Shima K, Murata Y and Kishi K (1997) The placenta is not the main source of leptin production in pregnant rat: gestational profile of leptin in plasma and adipose tissues Biochemical and Biophysical Research Communications 240 798–802
39. Lee G, Proence R, Montez JM, Carroll KM, Darvishzadeh JG, Lee JI and Friedman JM (1996) Abnormal splicing of the leptin receptor in diabetic mice Nature (London) 379 632–635
40. Linzer DIH and Arey BJ (1995) Ovarian prolactin receptors and their placental ligands. In The Somatotrophic Axis and the Reproductive Process in Health and Disease pp 28–39 Eds EY Adashi and MO Thorner. Serono Symposia USA. Springer Verlag, New York
41. Loucks AB and Heath EM (1994) Dietary restriction reduces luteinising hormone (LH) pulse frequency during waking hours and increases LH pulse amplitude during sleep in young menstruating women Journal of Clinical Endocrinology and Metabolism 78 910–915
42. McGregor GP, Desaga JF, Ehlenz K, Heese F, Hegele A, Lammer C, Peiser C and Lang RE (1996) Radioimmunological measurement of leptin in plasma of obese and diabetic human subjects Endocrinology 137 1501–1504
43. Malik KF and Young S, III (1996) Localisation of binding sites in the central nervous system for leptin (OB protein) in normal, obese (ob/ob) and diabetic (db/db) C57BL/6J mice Endocrinology 137 1497–1500
44. Martin GB, Walkden-Brown SW, Boukhil R, Tjondronegoro S, Miller DW, Fisher JS, Hotzel M-J, Restall BJ and Adams NR (1994) Non-photoperiodic inputs into seasonal breeding in male ruminants. In Perspectives in Comparative Endocrinology pp 574–585. Eds KG Davey, RE Peter and SS Tobe. National Research Council of Canada, Ottawa
45. Masuzaki H, Ogawa Y, Sagawa N et al. (1997) Nonadipose tissue production of leptin: leptin as a novel placenta-derived hormone in humans Nature Medicine 3 1029–1033
46. Matkovic V, Ilich JZ, Skugor M, Badenhop NE, Goel P, Clairmont A, Klisovic D, Nahhas and Landoll JD (1997) Leptin is inversely related to age at menarche in human females Journal of Clinical Endocrinology and Metabolism 82 3239–3245
47. Mercer JG, Hoggard N, Williams LM, Lawrence CB, Hannah LT, Morgan PJ and Trayhurn P (1996) Coexpression of leptin receptor and preproneuro-peptide Y mRNA in arcuate nucleus of mouse hypothalamus Journal of Neuroendocrinology 8 733–735
48. Morley JE (1987) Neuropeptide regulation of appetite and weight Endocrine Reviews 8 256–277
49. Mounzih K, Lu R and Chehab FF (1997) Leptin treatment rescues the sterility of genetically obese ob/ob males Endocrinology 138 1190–1193.
50. Nagatani S, Guthikonda P, Thompson RC, Tsukamura H, Maeda K-I and Foster DL (1998) Evidence for GnRH regulation by leptin: leptin administration prevents reduced pulsatile LH secretion during fasting Neuroendocrinology 67 370–376
51. Plant TM and Durrant AR (1997) Circulating leptin does not appear to provide a signal for triggering the initiation of puberty in the male rhesus monkey Endocrinology 138 4505–4508
52. Pomares CC, Galloway DB, Holmes JHG, Clarke IJ and Tilbrook AJ (1995) Lupin and cowpea supplements for growth, wool production and reproduction in rams Australian Journal of Experimental Biology 35 447–452
53. Porter DWF, Naylor AM, McNeilly AS and Lincoln DW (1993) Endocrine actions of central neuropeptide Y in the ewe: activation of the hypothalamo–pituitary–adrenal axis by exogenous neuropeptide Y and role of endogenous neuropeptide Y in the secretion of luteinizing hormone during the oestrous cycle Journal of Neuroendocrinology 5 163–174
54. Presse F, Sorokovosky I, Max J-P, Nicolaidis S and Nahon J-L (1996) Melanin-concentrating hormone is a potent anorectic peptide regulated by food-deprivation and glucopeinia in the rat Neuroscience 71 735–745
55. Qu D, Ludwig DS, Gammeltoft S, Piper M, Pelleymounter MA, Cullen MJ, Mathes WF, Przypek J, Kanarek R and Maratos-Flier E (1996) A role for melanin-concentration hormone in the central regulation of feeding behaviour Nature (London) 380 243–247
56. Ricardo V, Garcia-Mayor M, Andrade A, Rios M, Lage M, Dieguez C and Casanueva FF (1997) Serum leptin levels in normal children: relationship to age, gender, body mass index, pituitary–gonadal hormones, and pubertal stage Journal of Clinical Endocrinology and Metabolism 82 2849–2855
57. Roh S-G, Clarke IJ, Goding JW and Chen C The effect of leptin in growth hormone secretion in primary cultured ovine pituitary cells Neuroendocrinology (in press)
58. Rossi M, Choi SJ, O’Shea D, Miyoshi T, Ghatei MA and Bloom SR (1997) Melanin-concentration hormone acutely stimulates feeding, but chronic administration has no effect on body weight Endocrinology 138 351–355
59. Sahu A (1998) Evidence suggesting that galanin (GAL), melanin-concentrating hormone (MCH), neurotensin (NT), proopiomelanocortin (POMC) and neuropeptide Y (NPY) are targets of leptin signalling in the hypothalamus Endocrinology 139 795–798
60. Sahu A, Phelps CP, White JD, Crowley WR, Kalra SP and Kalra PS (1992) Steroidal regulation of hypothalamic neuropeptide Y release and gene expression Endocrinology 130 3331–3336
61. Schreihofer, DA, Renda, F and Cameron, JL (1996) Feeding-induced stimulation of luteinizing hormone secretion in male rhesus monkeys is not dependent on a rise in blood glucose concentration Endocrinology 137 3770–3776
62. Shetty PS (1946) Adaptive changes in basal metabolic rate and lean body mass in chronic undernutrition. Human starvation and its consequences Journal of the American Diet Association 22 582–587
63. Spicer LJ and Francisco CC (1997) The adipose obese gene product, leptin: evidence of a direct inhibitory role in ovarian function Endocrinology 138 3374–3379
64. Spicer LJ and Francisco CC (1998) Adipose obese gene product, leptin, inhibits bovine ovarian thecal cell steroidogenesis Biology of Reproduction 58:207–212
65. Thornton JE, Cheung CC, Clifton DK, Steiner RA (1997) Regulation of hypothalamic proopiomelanocrotin mRNA by leptin in ob/ob mice Endocrinology 138 5063–5065
66. Tomimatsu T, Yamaguci M, Murukami T et al. (1997) Increase of mouse leptin production by adipose tissue after midpregnancy: gestational profile of serum leptin concentration Biochemical and Biophysical Research Communications 240 213–215
67. Van der Walt LA, Wilmsen EN and Jenkins T (1978) Unusual sex hormone patterns among desert-dwelling hunter-gatherers Journal of Clinical Endocrinology and Metabolism 46 658–663
68. Weigle DS, Duell PB, Connor WE, Steiner RA, Soules MR and Kuijper JL (1997) Effect of fasting, re-feeding and dietary fat restriction on plasma leptin levels Journal of Clinical Endocrinology and Metabolism 82 561–565
69. Yen SSC Lifestyle and body composition effects on the ovary. In Endocrinology and Metabolic Clinics of North America Eds HG Burger and RI McLachlan. WB Saunders, Philadelphia (in press)
70. Yu WH, Kimura M, Walczewska A, Karanth S and McCann SM (1997) Role of leptin in hypothalamic–pituitary function Proceedings of the National Academy of Science USA 94 1023–1028
71. Zachow RJ and Magoffin DA (1997) Direct intraovarian effects of leptin: impairment of the synergistic action of insulin-like growth factor I on follicle-stimulating hormone-dependent estradiol-17β production by rat ovarian granulosa cells Endocrinology 138 847–850
72. Zamorano PL, Mahesh VB, De Sevilla LM, Chorich LP, Bhat GK and Brann DW (1997) Expression and localization of the leptin receptor in endocrine and neuroendocrine tissues of the rat Neuroendocrinology 65 223–228