Leptin gene is expressed in rat brown adipose tissue at birth

FASEB Journal

Volumn 11, Issue 5, 1997, Pages 382-387

  Dessolin, Sophie ^a   Schalling, Martin ^b   Champigny, Odette ^c   Lönnqvist, Fredrik ^b   Ailhaud, Gérard ^a   Dani, Christian ^a   Ricquier, Daniel ^c,d  

^a CENTRE DE BIOCHIMIE   (France)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c CNRS   (France)

^d CEREMOD/CNRS   (France)

Author keywords

birth; brown adipose tissue; ob; suckling

Indexed keywords

LEPTIN;

ADOLESCENT; ANIMAL TISSUE; ARTICLE; BROWN ADIPOSE TISSUE; CONTROLLED STUDY; ENERGY EXPENDITURE; FETUS; FOOD INTAKE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SATIETY; SUCKLING;

EID: 0030944542     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fasebj.11.5.9141506     Document Type: Article

References (24)

1. Zhang, Y., Proenca, R., Maffei, M., Barone, M., Leopold, L., and Friedman, J. M. (1994) Positional cloning of the mouse obese gene and its human homologue. Nature (London) 372, 425-432
2. Tartaglia, L. A., Dembski, M., Weng, X., Deng, N., Culpepper, J., Devos, R., Richards, G., Campfield, L. A., Clark, F. T., Dedds, J., Muir, C., Sanker, S., Morioarty, A., Moore, K. J., Smutko, J. S., Mays, G. G., Woolf, E. A., Monroe, C. A., and Tepper, R. I. (1995) Identification and expression cloning of a leptin receptor, OB-R. Cell 83, 1263-1271
3. Pelleymounter, M. A., Cullen, M. J., Baker, M. B., Hecht, R., Winters, D., Boone, T., and Collins, F. (1995) Effects of the obese gene product on body weight regulation in ob/ob mice. Science 269, 540-543
4. Halaas, J. L., Gajiwala, K. J., Maffei, M., Cohen, S. L., Chait, B. T., Rabinowitz, D., Lallone, R., Burley, S. K., and Friedmann, J. F. (1995) Weight-reducing effects of the plasma protein encoded by the obese gene. Science 269, 543-546
5. Lönnqvist, F. (1996) The obese (ob) gene and its product leptin - a new route toward obesity treatment in man? Q. J. Med. 89, 327-332
6. Collins, S., Kuhn, C. M., Petro, A. E., Swick, A. G., and Surwit, R. S. (1996) Role of leptin in fat regulation. Nature (London) 380, 677
7. Himms-Hagen, J., and Ricquier, D. (1997) Brown adipose tissue. In Handbook of Obesity (Bray, G., Bouchard, C., and James, W. P. T., eds) Marcel Dekker, New York In press
8. Nicholls, D. G., and Locke, R. (1984) Brown fat thermogenesis. Physiol. Rev. 64, 1-64
9. Ricquier, D., Casteilla, L. and Bouillaud, F. (1991) Molecular studies of the uncoupling protein. FASEB J. 5, 2237-2242
10. Lowell, B. B., S-Susulic, V., Hamann, A., Lawitts, J. A., Himms-Hagen, J., Boyer, B., Kozak, L. P., and Flier, J. S. (1993) Development of obesity in transgenic mice after genetic ablation of brown adipose tissue. Nature (London) 366, 740-742
11. Chomczynski, P., and Sacchi, N. (1987) Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162, 156-159
12. Ogawa, Y., Masuzaki, H., Isse, N., Okazaki, T., Mori, K., Shigemoto, M., Satoh, N., Tamura, N., Hosoda, K., Yoshimasa, Y., Jingami, H., Kawada, T., and Nakao, K. (1995) Molecular cloning of rat Obese cDNA and augmented gene expression in genetically obese Zucker fatty (fa/fa) rats. J. Clin. Invest. 96, 1647-1652
13. Schalling, M., Friberg, K., Seroogy, K., Riederer, P., Bird, E., Schiffman, S. N., Mailleux, P., Vanderhaegegben, L. L., Kuga, S., Goldstein, M., Kitahama, K., Luppi, P. H., Jouvet, M., and Hökfelt, T. (1990) Analysis of expression of cholecystokinin in dopamine cells in the ventral mesencephalon of several species and in humans with schizophrenia. Proc. Natl. Acad. Sci. USA 87, 8427-8431
14. Lönnqvist, F., Arner, P., Nordfors, L., and Schalling, M. (1995) Overexpression of the obese (ob) gene in human obese subjects. Nature Med. 1, 950-953
15. Ricquier, D., Bouillaud, F., Toumelin, P., Mory, G., Bazin, R., Arch, J., and Pénicaud, L. (1986) Expression of uncoupling protein mRNA in thermogenic or weakly thermogenic brown adipose tissue. Evidence for a rapid β-adrenoceptor-mediated and transcriptionally regulated step during activation of thermogenesis. J. Biol. Chem. 261, 13905-13910
16. Trayhurn, P., Thomas, M. E. A., Duncan, J. S., and Rayner, D. V. (1995) Effects of fasting and refeeding on ob gene expression in white adipose tissue of lean and obese (ob/ob) mice. FEBS Lett. 368, 488-490
17. Moinat, M., Deng, C., Muzzin, P., Assimacopoulos-Jeannat, F., Seydoux, J., Dulloo, A. G., and Giacobino, J. P. (1995) Modulation of obese gene expression in rat brown and white adipose tissues. FEBS Lett. 373, 131-134
18. Frederich, R. C., Löllman, B., Hamann, A., Napolitano-Rosen, A., Kahn, B. B., Lowell, B. B., and Flier, J. S. (1995) Expression of ob mRNA and its encoded protein in rodents: impact of nutrition and obesity. J. Clin. Invest. 96, 1658-1663
19. Murakami, T., and Shima, K. (1995) Cloning of rat obese cDNA and its expression in obese rats. Biochem. Biophys. Res. Commun. 209, 944-952
20. Maffei, M., Fei, H., Lee, G. H., Dani, C., Leroy, P., Zhang, Y., Proenca, R., Négrel, R., Ailhaud, G., and Friedman, J. F. (1995) Increased expression in adipocytes of ob mRNA in mice with lesions of the hypothalamus and with mutations at the db locus. Proc. Natl. Acad. Sci. USA 92, 6957-6960
21. Collins, S., and Surwitt, R. S. (1996) Pharmacological manipulation of ob expression in a dietary model of obesity. J. Biol. Chem. 271, 9437-9440
22. Barnard, T., and Skala, J. (1970) The development of brown adipose tissue. In Brown Adipose Tissue (Lindberg, O., ed) pp. 33-72, Elsevier, New York
23. Hennings, S. J., Chang, S. S. P., and Gisel, E. G. (1979) Ontogeny of feeding controls in suckling and weaning rats. Am. J. Physiol. 237, R187-R191
24. Himms-Hagen, J. (1995) Does thermoregulatory feeding occur in newborn infants? A novel view of the role of brown adipose tissue thermogenesis in control of food intake. Obesity Res. 3, 361-369