-
1
-
-
0028139089
-
Positional cloning of the mouse obese gene and ils human homologue
-
Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM: Positional cloning of the mouse obese gene and ils human homologue. Nature 372:425-1132, 1994
-
(1994)
Nature
, vol.372
, pp. 425-1132
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
-
2
-
-
0029859099
-
Leptin: The tale of an obesity gene
-
Caro JF, Sinha MK, Kolaczynski JW, Zhang PL, Considine RV: Leptin: the tale of an obesity gene. Diabetes 45:1455-1402, 1906
-
(1906)
Diabetes
, vol.45
, pp. 1455-11402
-
-
Caro, J.F.1
Sinha, M.K.2
Kolaczynski, J.W.3
Zhang, P.L.4
Considine, R.V.5
-
3
-
-
0029066265
-
Effects of the obese gene product on body weight regulation in ob/ob mice
-
Pelleymounter MA, Cullen MJ, Baker MB, Hecht R, Winters D, Bonne T, Collins F: Effects of the obese gene product on body weight regulation in ob/ob mice. Science 269:540-543, 1995
-
(1995)
Science
, vol.269
, pp. 540-543
-
-
Pelleymounter, M.A.1
Cullen, M.J.2
Baker, M.B.3
Hecht, R.4
Winters, D.5
Bonne, T.6
Collins, F.7
-
4
-
-
0029073613
-
Weight-reducing effects of the plasma protein encoded by the obese gene
-
Halaas H, Gajiwala K, Maffei M, Cohen S, Chait B, Rabinowitz D, Lallone R, Burley S, Friedman JS: Weight-reducing effects of the plasma protein encoded by the obese gene. Science 269:543-546, 1995
-
(1995)
Science
, vol.269
, pp. 543-546
-
-
Halaas, H.1
Gajiwala, K.2
Maffei, M.3
Cohen, S.4
Chait, B.5
Rabinowitz, D.6
Lallone, R.7
Burley, S.8
Friedman, J.S.9
-
5
-
-
0029048408
-
Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks
-
Campfield L, Smith F, Guisez Y, Devos R, Burn P: Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks. Science 269:546-548, 1995
-
(1995)
Science
, vol.269
, pp. 546-548
-
-
Campfield, L.1
Smith, F.2
Guisez, Y.3
Devos, R.4
Burn, P.5
-
6
-
-
0030878110
-
Congenital leptin deficiency is associated with severe early-onset obesity in humans
-
Montague CT, Farooqi IS, Whitehead JP, Soos MA, Rau H, Wareham NJ, Sewter CP, Digby JE, Mohammed SN, Hurst JA, Cheetham CH, Earley AR, Barnett AH, Prins JB, O'Rahilly S: Congenital leptin deficiency is associated with severe early-onset obesity in humans. Nature 387:903-908, 1997
-
(1997)
Nature
, vol.387
, pp. 903-908
-
-
Montague, C.T.1
Farooqi, I.S.2
Whitehead, J.P.3
Soos, M.A.4
Rau, H.5
Wareham, N.J.6
Sewter, C.P.7
Digby, J.E.8
Mohammed, S.N.9
Hurst, J.A.10
Cheetham, C.H.11
Earley, A.R.12
Barnett, A.H.13
Prins, J.B.14
O'Rahilly, S.15
-
7
-
-
2442654859
-
Identification and expression cloning of a leptin receptor, OB-R
-
Tartaglia LA, Dembski M, Weng X, Deng N, Culpepper J, Devos R, Richards GJ, Campfield LA, Clark FT, Deeds J, Muir C, Sanker S, Moriarty A, Moore KJ, Smutko JS, Mays GG, Woolf EA, Monroe CA, Tepper RI: Identification and expression cloning of a leptin receptor, OB-R. Cell 83:1263-1271, 1995
-
(1995)
Cell
, vol.83
, pp. 1263-1271
-
-
Tartaglia, L.A.1
Dembski, M.2
Weng, X.3
Deng, N.4
Culpepper, J.5
Devos, R.6
Richards, G.J.7
Campfield, L.A.8
Clark, F.T.9
Deeds, J.10
Muir, C.11
Sanker, S.12
Moriarty, A.13
Moore, K.J.14
Smutko, J.S.15
Mays, G.G.16
Woolf, E.A.17
Monroe, C.A.18
Tepper, R.I.19
-
8
-
-
13344259300
-
Evidence that the diabetes gene encodes the leptin receptor: Identification of a mutation in the leptin receptor gene in db/db mice
-
Chen H, Charlat O, Tartaglia LA, Woolf EA, Weng X, Ellis SJ, Lakey ND, Culpepper J, Moore KJ, Breitbart RE, Duyk GM, Tepper RI, Morgenstern JP: Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice. Cell 84:491-495, 1996
-
(1996)
Cell
, vol.84
, pp. 491-495
-
-
Chen, H.1
Charlat, O.2
Tartaglia, L.A.3
Woolf, E.A.4
Weng, X.5
Ellis, S.J.6
Lakey, N.D.7
Culpepper, J.8
Moore, K.J.9
Breitbart, R.E.10
Duyk, G.M.11
Tepper, R.I.12
Morgenstern, J.P.13
-
9
-
-
0030039272
-
Abnormal splicing of the leptin receptor in diabetic mice
-
Lee GH, Proenca R, Montez JM, Carroll KM, Darvishzadeh JG, Lee JI, Friedman JM: Abnormal splicing of the leptin receptor in diabetic mice. Nature 379:632-635, 1996
-
(1996)
Nature
, vol.379
, pp. 632-635
-
-
Lee, G.H.1
Proenca, R.2
Montez, J.M.3
Carroll, K.M.4
Darvishzadeh, J.G.5
Lee, J.I.6
Friedman, J.M.7
-
10
-
-
0344450708
-
A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction
-
Clement K, Vaisse C, Lahlou N, Cabrol S, Pelloux V, Cassuto D, Gourmelen M, Dina C, Chambaz J, Lacorte JM, Basdevant A, Bougneres P, Lebouc Y, Froguel P, Guy-Grand B: A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction. Nature 392:398-401, 1998
-
(1998)
Nature
, vol.392
, pp. 398-401
-
-
Clement, K.1
Vaisse, C.2
Lahlou, N.3
Cabrol, S.4
Pelloux, V.5
Cassuto, D.6
Gourmelen, M.7
Dina, C.8
Chambaz, J.9
Lacorte, J.M.10
Basdevant, A.11
Bougneres, P.12
Lebouc, Y.13
Froguel, P.14
Guy-Grand, B.15
-
11
-
-
0030015417
-
Defective STAT signaling by the leptin receptor in diabetic mice
-
Ghilardi N, Ziegler S, Wiestner A, Stoffel R, Heim MR, Skoda RC: Defective STAT signaling by the leptin receptor in diabetic mice. Proc Natl Acad Sci U S A 93:6231-6235, 1996
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 6231-6235
-
-
Ghilardi, N.1
Ziegler, S.2
Wiestner, A.3
Stoffel, R.4
Heim, M.R.5
Skoda, R.C.6
-
12
-
-
0032527071
-
Distributions of leptin receptor mRNA isoforms in the rat brain
-
Elmquist JK, Bjørbæk C, Ahima RS, Flier JS, Saper CB: Distributions of leptin receptor mRNA isoforms in the rat brain. J Comp Neurol 395:535-547, 1998
-
(1998)
J Comp Neurol
, vol.395
, pp. 535-547
-
-
Elmquist, J.K.1
Bjørbæk, C.2
Ahima, R.S.3
Flier, J.S.4
Saper, C.B.5
-
13
-
-
0031010408
-
Anatomic localization of alternatively spliced leptin receptors (OBR) in mouse brain and other tissues
-
Fei H, Okano HJ, Li C, Lee G-H, Zhao C, Darnell R, Friedman JM: Anatomic localization of alternatively spliced leptin receptors (OBR) in mouse brain and other tissues. Proc Natl Acad Sci U S A 94:7001-7005, 1997
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 7001-7005
-
-
Fei, H.1
Okano, H.J.2
Li, C.3
Lee, G.-H.4
Zhao, C.5
Darnell, R.6
Friedman, J.M.7
-
14
-
-
0031017561
-
Human blood-brain barrier leptin receptor binding and endocytosis in isolated human brain microvessels
-
Golden PL, Maccagnan TJ, Pardridge WM: Human blood-brain barrier leptin receptor binding and endocytosis in isolated human brain microvessels. J Clin Invest 99:14-18, 1997
-
(1997)
J Clin Invest
, vol.99
, pp. 14-18
-
-
Golden, P.L.1
Maccagnan, T.J.2
Pardridge, W.M.3
-
15
-
-
0031761385
-
Expression of leplin receptor isoforms in rat brain microvessels
-
Bjørbæk C, Elmquist JK, Michl P, Anima RS, van Bueren A, McCall AL, Flier JS: Expression of leplin receptor isoforms in rat brain microvessels. Endocrinology 139:3485-3491, 1998
-
(1998)
Endocrinology
, vol.139
, pp. 3485-3491
-
-
Bjørbæk, C.1
Elmquist, J.K.2
Michl, P.3
Anima, R.S.4
Van Bueren, A.5
McCall, A.L.6
Flier, J.S.7
-
16
-
-
0030482360
-
Hyperleptinemia in chronic renal failure
-
Iida M, Murakami T, Yamada M, Sei M, Kuwajima M, Mizuno A, Noma Y, Aono Y, Shima K : Hyperleptinemia in chronic renal failure. Horm Metab Res 28:724-727, 1996
-
(1996)
Horm Metab Res
, vol.28
, pp. 724-727
-
-
Iida, M.1
Murakami, T.2
Yamada, M.3
Sei, M.4
Kuwajima, M.5
Mizuno, A.6
Noma, Y.7
Aono, Y.8
Shima, K.9
-
17
-
-
8244232511
-
Plasma leptin is partly cleared by the kidney and is elevated in hemodialysis patients
-
Sharma K, Considine RV, Michael B, Dun SR, Weisberg LS, Kurnik BR, Kurnik PB, O'Connor J, Sinha M, Caro JF: Plasma leptin is partly cleared by the kidney and is elevated in hemodialysis patients. Kidney Int 51:1980-1985, 1997
-
(1997)
Kidney Int
, vol.51
, pp. 1980-1985
-
-
Sharma, K.1
Considine, R.V.2
Michael, B.3
Dun, S.R.4
Weisberg, L.S.5
Kurnik, B.R.6
Kurnik, P.B.7
O'Connor, J.8
Sinha, M.9
Caro, J.F.10
-
18
-
-
0031017938
-
Increased plasma leptin concentration in end-stage renal disease
-
Merabet E, Dagogo-Jack S, Coyne DW, Klein S, Santiago JV, Hmiel SP, Landt M: Increased plasma leptin concentration in end-stage renal disease. J Clin Endocrinol Metab 82:847-850, 1997
-
(1997)
J Clin Endocrinol Metab
, vol.82
, pp. 847-850
-
-
Merabet, E.1
Dagogo-Jack, S.2
Coyne, D.W.3
Klein, S.4
Santiago, J.V.5
Hmiel, S.P.6
Landt, M.7
-
19
-
-
0029776030
-
The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors
-
Baumann H, Morella KK, White DW, Dembski M, Bailon PS, Kim H, Lai CF, Tartaglia LA: The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors. Proc Natl Acad Sci U S A 93:8374-8378, 1996
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 8374-8378
-
-
Baumann, H.1
Morella, K.K.2
White, D.W.3
Dembski, M.4
Bailon, P.S.5
Kim, H.6
Lai, C.F.7
Tartaglia, L.A.8
-
20
-
-
0029739826
-
Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice
-
Vaisse C, Halaas JL, Horvath CM, Darnell JE Jr, Stoffel M, Friedman JM: Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice. Nat Genet 14:95-97, 1996
-
(1996)
Nat Genet
, vol.14
, pp. 95-97
-
-
Vaisse, C.1
Halaas, J.L.2
Horvath, C.M.3
Darnell J.E., Jr.4
Stoffel, M.5
Friedman, J.M.6
-
21
-
-
0031436148
-
Divergent signaling capacities of the long and short isoforms of the leptin receptor
-
Bjørbæk C, Uotani S, da Silva B, Flier JS: Divergent signaling capacities of the long and short isoforms of the leptin receptor. J Biol Chem 272:32686-32695, 1997
-
(1997)
J Biol Chem
, vol.272
, pp. 32686-32695
-
-
Bjørbæk, C.1
Uotani, S.2
Da Silva, B.3
Flier, J.S.4
-
22
-
-
13344295079
-
Senun immunoreactive leptin concentrations in normal weight and obese humans
-
Considine R, Sinha MK, Heiman M, Kriaticiunas A, Stephens TW, Nyce MR, Ohannesian P, Marco CC, Mckee L, Bauer TL, Caro JF: Senun immunoreactive leptin concentrations in normal weight and obese humans. N Engl J Med 334:292-295, 1995
-
(1995)
N Engl J Med
, vol.334
, pp. 292-295
-
-
Considine, R.1
Sinha, M.K.2
Heiman, M.3
Kriaticiunas, A.4
Stephens, T.W.5
Nyce, M.R.6
Ohannesian, P.7
Marco, C.C.8
Mckee, L.9
Bauer, T.L.10
Caro, J.F.11
-
23
-
-
0028845877
-
Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects
-
Maffei M, Halaas J, Ravussin E, Pratley RE, Lee GH, Zhang Y, Fei H, Kim S, Lallone R, Ranganathan S, Kem PS, Friedman JM: Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat Med 1:1155-1161, 1995
-
(1995)
Nat Med
, vol.1
, pp. 1155-1161
-
-
Maffei, M.1
Halaas, J.2
Ravussin, E.3
Pratley, R.E.4
Lee, G.H.5
Zhang, Y.6
Fei, H.7
Kim, S.8
Lallone, R.9
Ranganathan, S.10
Kem, P.S.11
Friedman, J.M.12
-
24
-
-
0019945866
-
The endocytotic rate constant: A cellular parameter for quantitating receptor-mediated endocytosis
-
Wiley HS, Cunningham DD: The endocytotic rate constant: a cellular parameter for quantitating receptor-mediated endocytosis. J Biol Chem 257:4222-4229, 1982
-
(1982)
J Biol Chem
, vol.257
, pp. 4222-4229
-
-
Wiley, H.S.1
Cunningham, D.D.2
-
25
-
-
0026765431
-
Internalization of the human insulin receptor: The insulin-independent pathway
-
Paccaud JP, Saddle K, Carpentier JL: Internalization of the human insulin receptor: the insulin-independent pathway. J Biol Chem 267:13101-13106, 1992
-
(1992)
J Biol Chem
, vol.267
, pp. 13101-13106
-
-
Paccaud, J.P.1
Saddle, K.2
Carpentier, J.L.3
-
26
-
-
0024544710
-
Potassium depletion and hypertonic medium reduce "non-coated" and clathrin-coated pit formation, as well as endocytosis through these two gates
-
Carpentier JL, Sawano F, Geiger D, Gorden P, Perrelet A, Orci L: Potassium depletion and hypertonic medium reduce "non-coated" and clathrin-coated pit formation, as well as endocytosis through these two gates. J Cell Physiol 138:519-526, 1989
-
(1989)
J Cell Physiol
, vol.138
, pp. 519-526
-
-
Carpentier, J.L.1
Sawano, F.2
Geiger, D.3
Gorden, P.4
Perrelet, A.5
Orci, L.6
-
27
-
-
0019983285
-
Interaction of platelet-derived growth factor with its fibroblast receptor demonstration of ligand degradation and receptor modulation
-
Heldin CH, Wasteson A, Westermark B: Interaction of platelet-derived growth factor with its fibroblast receptor demonstration of ligand degradation and receptor modulation. J Biol Chem 257:4216-4221, 1982
-
(1982)
J Biol Chem
, vol.257
, pp. 4216-4221
-
-
Heldin, C.H.1
Wasteson, A.2
Westermark, B.3
-
28
-
-
0025885433
-
Identification of a hydrophobic region in the carboxyl terminus of the platelet-derived growth factor β-receptor that is important for ligand-mediated endocytosis
-
Mori S, Claesson-Welsh L, Heldin CH: Identification of a hydrophobic region in the carboxyl terminus of the platelet-derived growth factor β-receptor that is important for ligand-mediated endocytosis. J Biol Chem 266:21158-21164, 1991
-
(1991)
J Biol Chem
, vol.266
, pp. 21158-21164
-
-
Mori, S.1
Claesson-Welsh, L.2
Heldin, C.H.3
-
29
-
-
0030920217
-
Leptin receptor action in hepatic cells
-
Wang Y, Kuropatwinski KK, White DW, Hawley TS, Hawley RG, Tartaglia LA, Baumann H: Leptin receptor action in hepatic cells. J Biol Chem 272:16216-16223, 1997
-
(1997)
J Biol Chem
, vol.272
, pp. 16216-16223
-
-
Wang, Y.1
Kuropatwinski, K.K.2
White, D.W.3
Hawley, T.S.4
Hawley, R.G.5
Tartaglia, L.A.6
Baumann, H.7
-
30
-
-
0030981063
-
Leptin receptor of Zucker fatty rat performs reduced signal transduction
-
Yamashita T, Murakami T, Iida M, Kuwajima M, Shima K: Leptin receptor of Zucker fatty rat performs reduced signal transduction. Diabetes 46:1077-1080, 1997
-
(1997)
Diabetes
, vol.46
, pp. 1077-1080
-
-
Yamashita, T.1
Murakami, T.2
Iida, M.3
Kuwajima, M.4
Shima, K.5
-
31
-
-
10544236913
-
Functional STAT 1 and 3 signaling by the lepun receptor (OB-R): Reduced expression of the rat fatty leptin receptor in transfected cells
-
Rosenblum CI, Tota M, Cully D, Smith T, Collum R, Qureshi S, Hess JF, Phillips MS, Hey PJ, Vongs A, Fong TM, Xu L, Chen HY, Smith RG, Schindler C, Van der Ploeg LH: Functional STAT 1 and 3 signaling by the lepun receptor (OB-R): reduced expression of the rat fatty leptin receptor in transfected cells. Endocrinology 137:5178-5181, 1996
-
(1996)
Endocrinology
, vol.137
, pp. 5178-5181
-
-
Rosenblum, C.I.1
Tota, M.2
Cully, D.3
Smith, T.4
Collum, R.5
Qureshi, S.6
Hess, J.F.7
Phillips, M.S.8
Hey, P.J.9
Vongs, A.10
Fong, T.M.11
Xu, L.12
Chen, H.Y.13
Smith, R.G.14
Schindler, C.15
Van Der Ploeg, L.H.16
-
33
-
-
0030003317
-
Protein targeting by tyrosine-and di-leucine-based signals: Evidence for distinct saturable components
-
Marks MS, Woodruff L, Ohono H, Bonifacino JS: Protein targeting by tyrosine-and di-leucine-based signals: evidence for distinct saturable components. J Cell Biol 135:341-354, 1996
-
(1996)
J Cell Biol
, vol.135
, pp. 341-354
-
-
Marks, M.S.1
Woodruff, L.2
Ohono, H.3
Bonifacino, J.S.4
-
34
-
-
0030989801
-
Identification of cytoplasmic motifs required for short prolactin receptor internalization
-
Vincent V, Goffin V, Rozakis-Adcock M, Momon JP, Kelly PA: Identification of cytoplasmic motifs required for short prolactin receptor internalization. J Biol Chem 272:7062-7068, 1997
-
(1997)
J Biol Chem
, vol.272
, pp. 7062-7068
-
-
Vincent, V.1
Goffin, V.2
Rozakis-Adcock, M.3
Momon, J.P.4
Kelly, P.A.5
-
35
-
-
0030013247
-
Distinct cytoplasmic domains of the growth hormone receptor are required for glucocorticoid- and phorbol ester-induced decreases in growth hormone (GH) binding: These domains are different from that reported for GH-induced receptor internalization
-
King APJ, Tseng MJ, Logsdon CD, Billestrup N, Carter-Su C: Distinct cytoplasmic domains of the growth hormone receptor are required for glucocorticoid- and phorbol ester-induced decreases in growth hormone (GH) binding: these domains are different from that reported for GH-induced receptor internalization. J Biol Chem 271:18088-18094, 1996
-
(1996)
J Biol Chem
, vol.271
, pp. 18088-18094
-
-
King, A.P.J.1
Tseng, M.J.2
Logsdon, C.D.3
Billestrup, N.4
Carter-Su, C.5
-
36
-
-
0025369327
-
Human growth hormone-stimulated growth of human cultured lymphocytes (IM-9) and its inhibition by phorbol diesters through downregulation of the hormone receptors: Possible involvement of phosphorylation of a 55,000 molecular weight protein associated with the receptor in the downregulation
-
Suzuki K, Suzuki S, Saito Y, Ikebuchi H, Terao T: Human growth hormone-stimulated growth of human cultured lymphocytes (IM-9) and its inhibition by phorbol diesters through downregulation of the hormone receptors: possible involvement of phosphorylation of a 55,000 molecular weight protein associated with the receptor in the downregulation. J Biol Chem 265:11320-11327, 1990
-
(1990)
J Biol Chem
, vol.265
, pp. 11320-11327
-
-
Suzuki, K.1
Suzuki, S.2
Saito, Y.3
Ikebuchi, H.4
Terao, T.5
-
37
-
-
0028829614
-
Dexamethasone-induced antagonism of growth hormone (GH) action by downregulation of GH binding in 3T3-F442A fibroblasts
-
King AP, Carter-Su C: Dexamethasone-induced antagonism of growth hormone (GH) action by downregulation of GH binding in 3T3-F442A fibroblasts. Endocrinology 136:4796-4803, 1995
-
(1995)
Endocrinology
, vol.136
, pp. 4796-4803
-
-
King, A.P.1
Carter-Su, C.2
-
38
-
-
0020150186
-
Endocytosis of peptide hormones and other ligands
-
Posner BI, Khan MN, Bergeron JJM: Endocytosis of peptide hormones and other ligands. Endocr Rev 3:280-298, 1982
-
(1982)
Endocr Rev
, vol.3
, pp. 280-298
-
-
Posner, B.I.1
Khan, M.N.2
Bergeron, J.J.M.3
-
39
-
-
0028838012
-
Dimerization of cell surface receptors in signal transduction
-
Heldin C-H: Dimerization of cell surface receptors in signal transduction. Cell 80:21.3-223, 1995
-
(1995)
Cell
, vol.80
, pp. 213-223
-
-
Heldin, C.-H.1
-
40
-
-
0028221574
-
Endocytosis and degradation of prolactin and its receptor in Chinese hamster ovary cells stably transfected with prolactin receptor cDNA
-
Genty N, Paly J, Edery M, Kelly PA, Djiane J, Salesse R: Endocytosis and degradation of prolactin and its receptor in Chinese hamster ovary cells stably transfected with prolactin receptor cDNA. Mol Cell Endocrinol 99:221-228, 1994
-
(1994)
Mol Cell Endocrinol
, vol.99
, pp. 221-228
-
-
Genty, N.1
Paly, J.2
Edery, M.3
Kelly, P.A.4
Djiane, J.5
Salesse, R.6
-
41
-
-
0025277673
-
Endocytosis and degradation of ovine prolactin by Nb2 lymphoma cells: Characterization and effects of agents known to alter prolactin-induced mitogenesis
-
Augustine EC, Kensinger RS: Endocytosis and degradation of ovine prolactin by Nb2 lymphoma cells: characterization and effects of agents known to alter prolactin-induced mitogenesis. Endocrinology 127:200-210, 1990
-
(1990)
Endocrinology
, vol.127
, pp. 200-210
-
-
Augustine, E.C.1
Kensinger, R.S.2
-
42
-
-
0023714041
-
Receptor-mediated endocytosis and degradation of bovine growth hormone in rat liver
-
Husman B, Gustafsson JA, Andersson G: Receptor-mediated endocytosis and degradation of bovine growth hormone in rat liver. Mol Cell Endocrinol 59:13-25, 1988
-
(1988)
Mol Cell Endocrinol
, vol.59
, pp. 13-25
-
-
Husman, B.1
Gustafsson, J.A.2
Andersson, G.3
-
44
-
-
0017334127
-
Role of the coated endocytic vesicle in the uptake of receptor-bound low-density lipoprotein in human fibroblasts
-
Anderson RG, Brown MS, Goldstein JL: Role of the coated endocytic vesicle in the uptake of receptor-bound low-density lipoprotein in human fibroblasts. Cell 10:351-364, 1977
-
(1977)
Cell
, vol.10
, pp. 351-364
-
-
Anderson, R.G.1
Brown, M.S.2
Goldstein, J.L.3
-
45
-
-
0026343342
-
Insulin receptors internalize by a rapid, saturable pathway requiring receptor autophosphorylation and an intact juxtamembrane region
-
Backer JM, Shoelson SE, Haring E, White MF: Insulin receptors internalize by a rapid, saturable pathway requiring receptor autophosphorylation and an intact juxtamembrane region. J Cell Biol 115:1535-1545, 1991
-
(1991)
J Cell Biol
, vol.115
, pp. 1535-1545
-
-
Backer, J.M.1
Shoelson, S.E.2
Haring, E.3
White, M.F.4
-
46
-
-
0030816392
-
Phosphorylation of four amino acid residues in the carboxyl terminus of the rat somatostatin receptor subtype 3 is crucial for its desensitization and intemalization
-
Roth A, Kreienkamp HJ, Meyerhof W, Richter D: Phosphorylation of four amino acid residues in the carboxyl terminus of the rat somatostatin receptor subtype 3 is crucial for its desensitization and intemalization. J Biol Chem 272:23764-23774, 1997
-
(1997)
J Biol Chem
, vol.272
, pp. 23764-23774
-
-
Roth, A.1
Kreienkamp, H.J.2
Meyerhof, W.3
Richter, D.4
-
47
-
-
0030797977
-
Protein phosphorylation events in exocytosis and endocytosis
-
Liu JP: Protein phosphorylation events in exocytosis and endocytosis. Clin Exp Pharmacol Physiol 24:611-618, 1997
-
(1997)
Clin Exp Pharmacol Physiol
, vol.24
, pp. 611-618
-
-
Liu, J.P.1
-
48
-
-
0030917081
-
Tyrosine phosphorylation controls internalization of CTLA-4 by regulating its interaction with clathrin-associated adaptor complex AP-2
-
Shiratori T, Miyatake S, Ohono H, Nakaseko C, Isono K, Bonifacino JS, Saito T: Tyrosine phosphorylation controls internalization of CTLA-4 by regulating its interaction with clathrin-associated adaptor complex AP-2. Immunity 6:583-589, 1997
-
(1997)
Immunity
, vol.6
, pp. 583-589
-
-
Shiratori, T.1
Miyatake, S.2
Ohono, H.3
Nakaseko, C.4
Isono, K.5
Bonifacino, J.S.6
Saito, T.7
-
49
-
-
0023091262
-
Acid-dependent ligand dissociation and recycling of LDL receptor mediated by growth factor homology region
-
Davis CG, Goldstein JL, Sudhof TC, Anderson RG, Russsel DW, Brown MS: Acid-dependent ligand dissociation and recycling of LDL receptor mediated by growth factor homology region. Nature 326:760-765, 1987
-
(1987)
Nature
, vol.326
, pp. 760-765
-
-
Davis, C.G.1
Goldstein, J.L.2
Sudhof, T.C.3
Anderson, R.G.4
Russsel, D.W.5
Brown, M.S.6
-
50
-
-
0031550523
-
A short form of leptin receptor performs signal transduction
-
Murakami T, Yamashita T, Iida M, Kuwajima M, Shima K: A short form of leptin receptor performs signal transduction. Biochem Biophys Res Commun 231:26-29, 1997
-
(1997)
Biochem Biophys Res Commun
, vol.231
, pp. 26-29
-
-
Murakami, T.1
Yamashita, T.2
Iida, M.3
Kuwajima, M.4
Shima, K.5
-
51
-
-
0028793697
-
Leptin levels reflect body lipid content in mice: Evidence for diet-induced resistance to leptin action
-
Frederich R, Hamann A, Anderson S, Lollmann B, Lowell BB, Flier JS: Leptin levels reflect body lipid content in mice: evidence for diet-induced resistance to leptin action. Nat Med 1:1311-1314, 1995
-
(1995)
Nat Med
, vol.1
, pp. 1311-1314
-
-
Frederich, R.1
Hamann, A.2
Anderson, S.3
Lollmann, B.4
Lowell, B.B.5
Flier, J.S.6
-
52
-
-
0029864416
-
Leptin enters the brain by a saturable system independent of insulin
-
Banks WA, Kastin AJ, Huang W, Jaspan JB, Maness LM: Leptin enters the brain by a saturable system independent of insulin. Peptides 17:305-311, 1996
-
(1996)
Peptides
, vol.17
, pp. 305-311
-
-
Banks, W.A.1
Kastin, A.J.2
Huang, W.3
Jaspan, J.B.4
Maness, L.M.5
-
53
-
-
0031154102
-
Cerebrospinal fluid leptin in anorexia nervosa: Correlation with nutritional status and potential role in resistance to weight gain
-
Mantzoros C, Flier JS, Lesen MD, Brewerton TD, Jimerson DC: Cerebrospinal fluid leptin in anorexia nervosa: correlation with nutritional status and potential role in resistance to weight gain. J Clin Endocrinol Metab 82:1845-1851, 1997
-
(1997)
J Clin Endocrinol Metab
, vol.82
, pp. 1845-1851
-
-
Mantzoros, C.1
Flier, J.S.2
Lesen, M.D.3
Brewerton, T.D.4
Jimerson, D.C.5
-
54
-
-
0029881125
-
Cerebrospinal fluid leptin levels: Relationship to plasma levels and to adiposity in humans
-
Schwartz MW, Peskind E, Raskind M, Boyko EJ, Porte D Jr: Cerebrospinal fluid leptin levels: relationship to plasma levels and to adiposity in humans. Nat Med 2:589-593, 1996
-
(1996)
Nat Med
, vol.2
, pp. 589-593
-
-
Schwartz, M.W.1
Peskind, E.2
Raskind, M.3
Boyko, E.J.4
Porte D., Jr.5
-
55
-
-
0030594830
-
Decreased cerebrospinal fluid/serum leptin ratio in obesity: A possible mechanism for leptin resistance
-
Caro JF, Kolaczynski JW, Nyce MR, Ohannesian JP, Opentanova I, Goldman WH, Lynn RB, Zhang PL, Sinha MK, Considine RV: Decreased cerebrospinal fluid/serum leptin ratio in obesity: a possible mechanism for leptin resistance. Lancet 348:159-161, 1996
-
(1996)
Lancet
, vol.348
, pp. 159-161
-
-
Caro, J.F.1
Kolaczynski, J.W.2
Nyce, M.R.3
Ohannesian, J.P.4
Opentanova, I.5
Goldman, W.H.6
Lynn, R.B.7
Zhang, P.L.8
Sinha, M.K.9
Considine, R.V.10
-
56
-
-
0030737953
-
Physiological response to long-term peripheral and central leptin infusion in lean and obese mice
-
Halaas JL, Boozer C, Blair-West J, Fidahusein N, Denton DA, Friedman JM: Physiological response to long-term peripheral and central leptin infusion in lean and obese mice. Proc Natl Acad Sci U S A 94:8878-8883, 1997
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 8878-8883
-
-
Halaas, J.L.1
Boozer, C.2
Blair-West, J.3
Fidahusein, N.4
Denton, D.A.5
Friedman, J.M.6
-
57
-
-
0027322295
-
Serum proteins bypass the blood-brain fluid barriers for extracellular entry to the central nervous system
-
Broadwell RD, Sofroniew MV: Serum proteins bypass the blood-brain fluid barriers for extracellular entry to the central nervous system. Exp Neurol 120:24:5-263, 1993
-
(1993)
Exp Neurol
, vol.120
, Issue.24
, pp. 5-263
-
-
Broadwell, R.D.1
Sofroniew, M.V.2
-
59
-
-
1842405349
-
Leptin directly alters lipid partitioning in skeletal muscle
-
Muoio DM, Dohn GL, Fiedorek FT Jr, Tapscott EB, Coleman RA: Leptin directly alters lipid partitioning in skeletal muscle. Diabetes 46:1360-1363, 1997
-
(1997)
Diabetes
, vol.46
, pp. 1360-1363
-
-
Muoio, D.M.1
Dohn, G.L.2
Fiedorek F.T., Jr.3
Tapscott, E.B.4
Coleman, R.A.5
-
60
-
-
0031467631
-
Direct effects of leptin on brown and white adipose tissue
-
Siegrist-Kaiser CA, Pauli V, Juge-Aubry CE, Boss O, Pernin A, Chin WW, Cusin I, Rohner-Jeanrenaud F, Burger AG, Zapf J, Meier CA: Direct effects of leptin on brown and white adipose tissue. J Clin Invest 100:2858-2864, 1997
-
(1997)
J Clin Invest
, vol.100
, pp. 2858-2864
-
-
Siegrist-Kaiser, C.A.1
Pauli, V.2
Juge-Aubry, C.E.3
Boss, O.4
Pernin, A.5
Chin, W.W.6
Cusin, I.7
Rohner-Jeanrenaud, F.8
Burger, A.G.9
Zapf, J.10
Meier, C.A.11
-
61
-
-
0038189958
-
Antagonism by cortisone of the linear growth induced in hypopituitary patients and hypophysectiomized rats by human growth hormone
-
Soyka LF, Crawford JD: Antagonism by cortisone of the linear growth induced in hypopituitary patients and hypophysectiomized rats by human growth hormone. J Clin Endocrinol Metab 25:469-475, 1965
-
(1965)
J Clin Endocrinol Metab
, vol.25
, pp. 469-475
-
-
Soyka, L.F.1
Crawford, J.D.2
-
62
-
-
0030903264
-
Glucocorticoids as counterregulatory hormones of leptin: Toward an understanding of leptin resistance
-
Zakrzewska KE, Cusin I, Sainsbury A, Rohner-Jeanrenaud F, Jeanrenaud B: Glucocorticoids as counterregulatory hormones of leptin: toward an understanding of leptin resistance. Diabetes 46:717-719, 1997
-
(1997)
Diabetes
, vol.46
, pp. 717-719
-
-
Zakrzewska, K.E.1
Cusin, I.2
Sainsbury, A.3
Rohner-Jeanrenaud, F.4
Jeanrenaud, B.5
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