The hallmarks of fibroblast ageing

Mechanisms of Ageing and Development

Volumn 138, Issue 1, 2014, Pages 26-44

  Tigges, Julia ^a   Krutmann, Jean ^a   Fritsche, Ellen ^a   Haendeler, Judith ^a,b   Schaal, Heiner ^b   Fischer, Jens W ^b   Kalfalah, Faiza ^b   Reinke, Hans ^a,b   Reifenberger, Guido ^b   Stühler, Kai ^b   Ventura, Natascia ^a,b   Gundermann, Sabrina ^c   Boukamp, Petra ^c   Boege, Fritz ^b  

^a IUF LEIBNIZ RESEARCH INSTITUTE FOR ENVIRONMENTAL MEDICINE   (Germany)

^b HEINRICH HEINE UNIVERSITY   (Germany)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

Altered proteostasis; Cellular senescence; Dermal fibroblasts; DNA damage; Extrinsic skin ageing; Mitochondrial dysfunction

Indexed keywords

HISTONE H2AX; HYALURONIC ACID SYNTHASE; MATRIX METALLOPROTEINASE; MESSENGER RNA; MICRORNA; MITOCHONDRIAL DNA; NICOTINAMIDE ADENINE DINUCLEOTIDE; PROTEASOME; REACTIVE OXYGEN METABOLITE; SIRTUIN; SYNTHETASE; UNCLASSIFIED DRUG;

AGING; AUTOPHAGY; CELL AGING; CELLULAR STRESS RESPONSE; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMOSOME ABERRATION; CIRCADIAN RHYTHM; CYTOKINE RELEASE; CYTOSKELETON; DERMIS; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA ADDUCT; DNA DETERMINATION; DOUBLE STRANDED DNA BREAK; DOWN REGULATION; EPIGENETICS; EXCISION REPAIR; FIBROBLAST CULTURE; GENOMIC INSTABILITY; GROWTH DISORDER; HUMAN; IN VITRO STUDY; MICROENVIRONMENT; MISMATCH REPAIR; MUTATIONAL ANALYSIS; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN HOMEOSTASIS; PROTEIN SECRETION; REVIEW; RNA PROCESSING; SENESCENCE; SIGNAL TRANSDUCTION; SKIN BIOPSY; SKIN FIBROBLAST; TELOMERE SHORTENING; TRANSPOSON; BIOLOGICAL MODEL; CUTANEOUS PARAMETERS; CYTOLOGY; EXTRACELLULAR MATRIX; FIBROBLAST; FUNCTIONS OF THE SKIN AND ITS APPENDAGES; METABOLISM; PHYSIOLOGY; SKIN;

AGING; CELL AGING; EXTRACELLULAR MATRIX; FIBROBLASTS; HUMANS; MODELS, BIOLOGICAL; PROTEASOME ENDOPEPTIDASE COMPLEX; SKIN; SKIN AGING; SKIN PHYSIOLOGICAL PHENOMENA;

EID: 84898862913     PISSN: 00476374     EISSN: 18726216     Source Type: Journal    
DOI: 10.1016/j.mad.2014.03.004     Document Type: Article

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