메뉴 건너뛰기




Volumn 45, Issue 10, 2010, Pages 801-813

Skin and brain age together: The role of hormones in the ageing process

Author keywords

Ageing; Alzheimer's disease; Central nervous system; Growth factors; Sex steroids; Skin

Indexed keywords

17ALPHA ESTRADIOL; 2 HYDROXYESTRADIOL; 4 HYDROXYESTRADIOL; AMYLOID BETA PROTEIN; CONJUGATED ESTROGEN; DYDROGESTERONE PLUS ESTRADIOL; ESTRADIOL; ESTRADIOL VALERATE; ESTRIOL; ESTRONE; ETHINYLESTRADIOL; GLYCOLIC ACID; GROWTH HORMONE; IBUTAMOREN; MEDROXYPROGESTERONE ACETATE; MESTRANOL; PRASTERONE; PRASTERONE SULFATE; PROGESTERONE; QUINESTROL; RECOMBINANT GROWTH HORMONE; RECOMBINANT SOMATOMEDIN C; SEX HORMONE; SOMATOMEDIN C; TESTOSTERONE; TRANSFORMING GROWTH FACTOR BETA;

EID: 77956986751     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exger.2010.08.005     Document Type: Review
Times cited : (71)

References (174)
  • 1
    • 0021950283 scopus 로고
    • Somatomedin-C synergizes with follicle-stimulating hormone in the acquisition of progestin biosynthetic capacity by cultured rat granulosa cells
    • Adashi E.Y., Resnick C.E., Svoboda M.E., Van Wyk J.J. Somatomedin-C synergizes with follicle-stimulating hormone in the acquisition of progestin biosynthetic capacity by cultured rat granulosa cells. Endocrinology 1985, 116:2135-2142.
    • (1985) Endocrinology , vol.116 , pp. 2135-2142
    • Adashi, E.Y.1    Resnick, C.E.2    Svoboda, M.E.3    Van Wyk, J.J.4
  • 5
    • 0030890046 scopus 로고    scopus 로고
    • The effects of ageing on wound healing: immunolocalisation of growth factors and their receptors in a murine incisional model
    • Ashcroft G.S., Horan M.A., Ferguson M.W. The effects of ageing on wound healing: immunolocalisation of growth factors and their receptors in a murine incisional model. J. Anat. 1997, 190(Pt 3):351-365.
    • (1997) J. Anat. , vol.190 , Issue.PART 3 , pp. 351-365
    • Ashcroft, G.S.1    Horan, M.A.2    Ferguson, M.W.3
  • 7
    • 14844285759 scopus 로고    scopus 로고
    • Dysregulation of the hypothalamic-pituitary-gonadal axis with menopause and andropause promotes neurodegenerative senescence
    • Atwood C.S., Meethal S.V., Liu T., Wilson A.C., Gallego M., Smith M.A., Bowen R.L. Dysregulation of the hypothalamic-pituitary-gonadal axis with menopause and andropause promotes neurodegenerative senescence. J. Neuropathol. Exp. Neurol. 2005, 64:93-103.
    • (2005) J. Neuropathol. Exp. Neurol. , vol.64 , pp. 93-103
    • Atwood, C.S.1    Meethal, S.V.2    Liu, T.3    Wilson, A.C.4    Gallego, M.5    Smith, M.A.6    Bowen, R.L.7
  • 10
    • 0017166058 scopus 로고
    • Specific chromosome aberrations in senescent fibroblast cell lines derived from human embryos
    • Benn P.A. Specific chromosome aberrations in senescent fibroblast cell lines derived from human embryos. Am. J. Hum. Genet. 1976, 28:465-473.
    • (1976) Am. J. Hum. Genet. , vol.28 , pp. 465-473
    • Benn, P.A.1
  • 12
    • 0042018741 scopus 로고    scopus 로고
    • Breast cancer and hormone-replacement therapy in the Million Women Study
    • Beral V. Breast cancer and hormone-replacement therapy in the Million Women Study. Lancet 2003, 362:419-427.
    • (2003) Lancet , vol.362 , pp. 419-427
    • Beral, V.1
  • 13
    • 0028819489 scopus 로고
    • Estradiol enhances brain glucose uptake in ovariectomized rats
    • Bishop J., Simpkins J.W. Estradiol enhances brain glucose uptake in ovariectomized rats. Brain Res. Bull. 1995, 36:315-320.
    • (1995) Brain Res. Bull. , vol.36 , pp. 315-320
    • Bishop, J.1    Simpkins, J.W.2
  • 14
    • 0035198634 scopus 로고    scopus 로고
    • A study of French centenarians: are ACE and APOE associated with longevity?
    • Blanche H., Cabanne L., Sahbatou M., Thomas G. A study of French centenarians: are ACE and APOE associated with longevity?. CR Acad. Sci. III 2001, 324:129-135.
    • (2001) CR Acad. Sci. III , vol.324 , pp. 129-135
    • Blanche, H.1    Cabanne, L.2    Sahbatou, M.3    Thomas, G.4
  • 16
    • 18444393384 scopus 로고    scopus 로고
    • Musculoskeletal effects of the recombinant human IGF-I/lGF binding protein-3 complex in osteoporotic patients with proximal femoral 11I fracture: a double-blind, placebo-controlled pilot study
    • Boonen S., Rosen C., Bouillon R., Sommer A., McKay M., Rosen D., Adams S., Broos P., Lenaerts J., Raus J., Vanderschueren D., Geusens P. Musculoskeletal effects of the recombinant human IGF-I/lGF binding protein-3 complex in osteoporotic patients with proximal femoral 11I fracture: a double-blind, placebo-controlled pilot study. J. Clin. Endocrinol. Metab. 2002, 87:1593-1599.
    • (2002) J. Clin. Endocrinol. Metab. , vol.87 , pp. 1593-1599
    • Boonen, S.1    Rosen, C.2    Bouillon, R.3    Sommer, A.4    McKay, M.5    Rosen, D.6    Adams, S.7    Broos, P.8    Lenaerts, J.9    Raus, J.10    Vanderschueren, D.11    Geusens, P.12
  • 17
    • 0034729071 scopus 로고    scopus 로고
    • Hormone replacement therapy and the skin
    • Brincat M.P. Hormone replacement therapy and the skin. Maturitas 2000, 35:107-117.
    • (2000) Maturitas , vol.35 , pp. 107-117
    • Brincat, M.P.1
  • 18
    • 0034457514 scopus 로고    scopus 로고
    • A prospective longitudinal study of serum testosterone, dehydroepiandrosterone sulfate, and sex hormone-binding globulin levels through the menopause transition
    • Burger H.G., Dudley E.C., Cui J., Dennerstein L., Hopper J.L. A prospective longitudinal study of serum testosterone, dehydroepiandrosterone sulfate, and sex hormone-binding globulin levels through the menopause transition. J. Clin. Endocrinol. Metab. 2000, 85:2832-2838.
    • (2000) J. Clin. Endocrinol. Metab. , vol.85 , pp. 2832-2838
    • Burger, H.G.1    Dudley, E.C.2    Cui, J.3    Dennerstein, L.4    Hopper, J.L.5
  • 20
    • 0030459108 scopus 로고    scopus 로고
    • Does hormonal skin aging exist? A study of the influence of different hormone therapy regimens on the skin of postmenopausal women using non-invasive measurement techniques
    • Callens A., Vaillant L., Lecomte P., Berson M., Gall Y., Lorette G. Does hormonal skin aging exist? A study of the influence of different hormone therapy regimens on the skin of postmenopausal women using non-invasive measurement techniques. Dermatology 1996, 193:289-294.
    • (1996) Dermatology , vol.193 , pp. 289-294
    • Callens, A.1    Vaillant, L.2    Lecomte, P.3    Berson, M.4    Gall, Y.5    Lorette, G.6
  • 21
    • 0345862282 scopus 로고    scopus 로고
    • Insulin-like growth factor I and Alzheimer's disease: therapeutic prospects?
    • Carro E., Torres-Aleman I. Insulin-like growth factor I and Alzheimer's disease: therapeutic prospects?. Expert Rev. Neurother. 2004, 4:79-86.
    • (2004) Expert Rev. Neurother. , vol.4 , pp. 79-86
    • Carro, E.1    Torres-Aleman, I.2
  • 22
    • 33745888080 scopus 로고    scopus 로고
    • Serum insulin-like growth factor I in brain function
    • Carro E., Torres-Aleman I. Serum insulin-like growth factor I in brain function. Keio J. Med. 2006, 55:59-63.
    • (2006) Keio J. Med. , vol.55 , pp. 59-63
    • Carro, E.1    Torres-Aleman, I.2
  • 23
  • 28
    • 0042334918 scopus 로고    scopus 로고
    • Expression of peroxisome proliferator-activated receptor and CCAAT/enhancer binding protein transcription factors in cultured human sebocytes
    • Chen W., Yang C.C., Sheu H.M., Seltmann H., Zouboulis C.C. Expression of peroxisome proliferator-activated receptor and CCAAT/enhancer binding protein transcription factors in cultured human sebocytes. J. Invest. Dermatol. 2003, 121:441-447.
    • (2003) J. Invest. Dermatol. , vol.121 , pp. 441-447
    • Chen, W.1    Yang, C.C.2    Sheu, H.M.3    Seltmann, H.4    Zouboulis, C.C.5
  • 29
    • 33947520006 scopus 로고    scopus 로고
    • Long-term treatment with recombinant insulin-like growth factor (IGF)-I in children with severe IGF-I deficiency due to growth hormone insensitivity
    • Chernausek S.D., Backeljauw P.F., Frane J., Kuntze J., Underwood L.E. Long-term treatment with recombinant insulin-like growth factor (IGF)-I in children with severe IGF-I deficiency due to growth hormone insensitivity. J. Clin. Endocrinol. Metab. 2007, 92:902-910.
    • (2007) J. Clin. Endocrinol. Metab. , vol.92 , pp. 902-910
    • Chernausek, S.D.1    Backeljauw, P.F.2    Frane, J.3    Kuntze, J.4    Underwood, L.E.5
  • 30
    • 33646863656 scopus 로고    scopus 로고
    • The quest for genetic determinants of human longevity: challenges and insights
    • Christensen K., Johnson T.E., Vaupel J.W. The quest for genetic determinants of human longevity: challenges and insights. Nat. Rev. Genet. 2006, 7:436-448.
    • (2006) Nat. Rev. Genet. , vol.7 , pp. 436-448
    • Christensen, K.1    Johnson, T.E.2    Vaupel, J.W.3
  • 31
    • 13944261231 scopus 로고    scopus 로고
    • Rejuvenation of aged progenitor cells by exposure to a young systemic environment
    • Conboy I.M., Conboy M.J., Wagers A.J., Girma E.R., Weissman I.L., Rando T.A. Rejuvenation of aged progenitor cells by exposure to a young systemic environment. Nature 2005, 433:760-764.
    • (2005) Nature , vol.433 , pp. 760-764
    • Conboy, I.M.1    Conboy, M.J.2    Wagers, A.J.3    Girma, E.R.4    Weissman, I.L.5    Rando, T.A.6
  • 33
    • 0033304979 scopus 로고    scopus 로고
    • Growth hormone and insulin-like growth factors have different effects on sebaceous cell growth and differentiation
    • Deplewski D., Rosenfield R.L. Growth hormone and insulin-like growth factors have different effects on sebaceous cell growth and differentiation. Endocrinology 1999, 140:4089-4094.
    • (1999) Endocrinology , vol.140 , pp. 4089-4094
    • Deplewski, D.1    Rosenfield, R.L.2
  • 34
    • 0005096726 scopus 로고
    • Tissue concentrations of somatomedin C: further evidence for multiple sites of synthesis and paracrine or autocrine mechanisms of action
    • D'Ercole A.J., Stiles A.D., Underwood L.E. Tissue concentrations of somatomedin C: further evidence for multiple sites of synthesis and paracrine or autocrine mechanisms of action. Proc. Natl. Acad. Sci. USA 1984, 81:935-939.
    • (1984) Proc. Natl. Acad. Sci. USA , vol.81 , pp. 935-939
    • D'Ercole, A.J.1    Stiles, A.D.2    Underwood, L.E.3
  • 36
    • 0030901602 scopus 로고    scopus 로고
    • Does estrogen prevent skin aging? Results from the First National Health and Nutrition Examination Survey (NHANES I)
    • Dunn L.B., Damesyn M., Moore A.A., Reuben D.B., Greendale G.A. Does estrogen prevent skin aging? Results from the First National Health and Nutrition Examination Survey (NHANES I). Arch. Dermatol. 1997, 133:339-342.
    • (1997) Arch. Dermatol. , vol.133 , pp. 339-342
    • Dunn, L.B.1    Damesyn, M.2    Moore, A.A.3    Reuben, D.B.4    Greendale, G.A.5
  • 37
    • 0031017154 scopus 로고    scopus 로고
    • C-reactive protein-like immunoreactivity in the neurofibrillary tangles of Alzheimer's disease
    • Duong T., Nikolaeva M., Acton P.J. C-reactive protein-like immunoreactivity in the neurofibrillary tangles of Alzheimer's disease. Brain Res. 1997, 749:152-156.
    • (1997) Brain Res. , vol.749 , pp. 152-156
    • Duong, T.1    Nikolaeva, M.2    Acton, P.J.3
  • 38
    • 0035230140 scopus 로고    scopus 로고
    • Ageing and the immune system
    • discussion 139-45, 146-9
    • Effros R.B. Ageing and the immune system. Novartis Found. Symp. 2001, 235:130-139. discussion 139-45, 146-9.
    • (2001) Novartis Found. Symp. , vol.235 , pp. 130-139
    • Effros, R.B.1
  • 39
    • 0036141548 scopus 로고    scopus 로고
    • The aged epidermal permeability barrier: basis for functional abnormalities
    • vii
    • Elias P.M., Ghadially R. The aged epidermal permeability barrier: basis for functional abnormalities. Clin. Geriatr. Med. 2002, 18:103-120. vii.
    • (2002) Clin. Geriatr. Med. , vol.18 , pp. 103-120
    • Elias, P.M.1    Ghadially, R.2
  • 40
    • 0015106113 scopus 로고
    • Diurnal cycles in plasma FSH, testosterone and cortisol in men
    • Faiman C., Winter J.S. Diurnal cycles in plasma FSH, testosterone and cortisol in men. J. Clin. Endocrinol. Metab. 1971, 33:186-192.
    • (1971) J. Clin. Endocrinol. Metab. , vol.33 , pp. 186-192
    • Faiman, C.1    Winter, J.S.2
  • 42
    • 22044441719 scopus 로고    scopus 로고
    • Effects of hormones on aging of the CNS, the immune system and the skin in rats
    • discussion 176-9
    • Fernandez-Tresguerres Hernandez J.A. Effects of hormones on aging of the CNS, the immune system and the skin in rats. An. Real Acad. Nac. Med. (Madr.) 2004, 121:157-176. discussion 176-9.
    • (2004) An. Real Acad. Nac. Med. (Madr.) , vol.121 , pp. 157-176
    • Fernandez-Tresguerres Hernandez, J.A.1
  • 45
    • 0033975581 scopus 로고    scopus 로고
    • Human immunosenescence: the prevailing of innate immunity, the failing of clonotypic immunity, and the filling of immunological space
    • Franceschi C., Bonafe M., Valensin S. Human immunosenescence: the prevailing of innate immunity, the failing of clonotypic immunity, and the filling of immunological space. Vaccine 2000, 18:1717-1720.
    • (2000) Vaccine , vol.18 , pp. 1717-1720
    • Franceschi, C.1    Bonafe, M.2    Valensin, S.3
  • 46
    • 0035016799 scopus 로고    scopus 로고
    • Sebocytes are the key regulators of androgen homeostasis in human skin
    • Fritsch M., Orfanos C.E., Zouboulis C.C. Sebocytes are the key regulators of androgen homeostasis in human skin. J. Invest. Dermatol. 2001, 116:793-800.
    • (2001) J. Invest. Dermatol. , vol.116 , pp. 793-800
    • Fritsch, M.1    Orfanos, C.E.2    Zouboulis, C.C.3
  • 47
    • 0141782610 scopus 로고    scopus 로고
    • The effects of an estrogen and glycolic acid cream on the facial skin of postmenopausal women: a randomized histologic study
    • Fuchs K.O., Solis O., Tapawan R., Paranjpe J. The effects of an estrogen and glycolic acid cream on the facial skin of postmenopausal women: a randomized histologic study. Cutis 2003, 71:481-488.
    • (2003) Cutis , vol.71 , pp. 481-488
    • Fuchs, K.O.1    Solis, O.2    Tapawan, R.3    Paranjpe, J.4
  • 48
    • 0036402101 scopus 로고    scopus 로고
    • Age-related changes in Type 1 and Type 2 cytokine production in humans
    • Gardner E.M., Murasko D.M. Age-related changes in Type 1 and Type 2 cytokine production in humans. Biogerontology 2002, 3:271-290.
    • (2002) Biogerontology , vol.3 , pp. 271-290
    • Gardner, E.M.1    Murasko, D.M.2
  • 49
    • 1242344871 scopus 로고    scopus 로고
    • A mechanistic model for the aging of human skin
    • Giacomoni P.U., Rein G. A mechanistic model for the aging of human skin. Micron 2004, 35:179-184.
    • (2004) Micron , vol.35 , pp. 179-184
    • Giacomoni, P.U.1    Rein, G.2
  • 51
    • 0020096171 scopus 로고
    • Age-associated changes in the skin
    • Gilchrest B.A. Age-associated changes in the skin. J. Am. Geriatr. Soc. 1982, 30:139-143.
    • (1982) J. Am. Geriatr. Soc. , vol.30 , pp. 139-143
    • Gilchrest, B.A.1
  • 52
    • 0020573584 scopus 로고
    • In vitro assessment of keratinocyte aging
    • Gilchrest B.A. In vitro assessment of keratinocyte aging. J. Invest. Dermatol. 1983, 81:184s-189s.
    • (1983) J. Invest. Dermatol. , vol.81
    • Gilchrest, B.A.1
  • 53
    • 34547223148 scopus 로고    scopus 로고
    • Sex steroids and cutaneous wound healing: the contrasting influences of estrogens and androgens
    • Gilliver S.C., Ashcroft G.S. Sex steroids and cutaneous wound healing: the contrasting influences of estrogens and androgens. Climacteric 2007, 10:276-288.
    • (2007) Climacteric , vol.10 , pp. 276-288
    • Gilliver, S.C.1    Ashcroft, G.S.2
  • 54
    • 34547931089 scopus 로고    scopus 로고
    • Androgens influence expression of matrix proteins and proteolytic factors during cutaneous wound healing
    • Gilliver S.C., Ruckshanthi J.P., Atkinson S.J., Ashcroft G.S. Androgens influence expression of matrix proteins and proteolytic factors during cutaneous wound healing. Lab. Invest. 2007, 87:871-881.
    • (2007) Lab. Invest. , vol.87 , pp. 871-881
    • Gilliver, S.C.1    Ruckshanthi, J.P.2    Atkinson, S.J.3    Ashcroft, G.S.4
  • 55
    • 36549002699 scopus 로고    scopus 로고
    • Morphological changes associated with aging: age spots and the microinflammatory model of skin aging
    • Goyarts E., Muizzuddin N., Maes D., Giacomoni P.U. Morphological changes associated with aging: age spots and the microinflammatory model of skin aging. Ann. NY Acad. Sci. 2007, 1119:32-39.
    • (2007) Ann. NY Acad. Sci. , vol.1119 , pp. 32-39
    • Goyarts, E.1    Muizzuddin, N.2    Maes, D.3    Giacomoni, P.U.4
  • 56
    • 0025884064 scopus 로고
    • Age, disease, and changing sex hormone levels in middle-aged men: results of the Massachusetts Male Aging Study
    • Gray A., Feldman H.A., McKinlay J.B., Longcope C. Age, disease, and changing sex hormone levels in middle-aged men: results of the Massachusetts Male Aging Study. J. Clin. Endocrinol. Metab. 1991, 73:1016-1025.
    • (1991) J. Clin. Endocrinol. Metab. , vol.73 , pp. 1016-1025
    • Gray, A.1    Feldman, H.A.2    McKinlay, J.B.3    Longcope, C.4
  • 59
    • 0031015949 scopus 로고    scopus 로고
    • Two-year treatment of growth hormone (GH) receptor deficiency with recombinant insulin-like growth factor I in 22 children: comparison of two dosage levels and to GH-treated GH deficiency
    • Guevara-Aguirre J., Rosenbloom A.L., Vasconez O., Martinez V., Gargosky S.E., Allen L., Rosenfeld R.G. Two-year treatment of growth hormone (GH) receptor deficiency with recombinant insulin-like growth factor I in 22 children: comparison of two dosage levels and to GH-treated GH deficiency. J. Clin. Endocrinol. Metab. 1997, 82:629-633.
    • (1997) J. Clin. Endocrinol. Metab. , vol.82 , pp. 629-633
    • Guevara-Aguirre, J.1    Rosenbloom, A.L.2    Vasconez, O.3    Martinez, V.4    Gargosky, S.E.5    Allen, L.6    Rosenfeld, R.G.7
  • 60
    • 0027374886 scopus 로고
    • Nerve growth factor as a neurotrophic agent
    • Guroff G. Nerve growth factor as a neurotrophic agent. Ann. NY Acad. Sci. 1993, 692:51-59.
    • (1993) Ann. NY Acad. Sci. , vol.692 , pp. 51-59
    • Guroff, G.1
  • 61
    • 0029932529 scopus 로고    scopus 로고
    • The improved organ maintenance of the human sebaceous gland: modeling in vitro the effects of epidermal growth factor, androgens, estrogens, 13-cis retinoic acid, and phenol red
    • Guy R., Ridden C., Kealey T. The improved organ maintenance of the human sebaceous gland: modeling in vitro the effects of epidermal growth factor, androgens, estrogens, 13-cis retinoic acid, and phenol red. J. Invest. Dermatol. 1996, 106:454-460.
    • (1996) J. Invest. Dermatol. , vol.106 , pp. 454-460
    • Guy, R.1    Ridden, C.2    Kealey, T.3
  • 63
    • 54249095698 scopus 로고    scopus 로고
    • Selective estrogen receptor modulators accelerate cutaneous wound healing in ovariectomised female mice
    • Hardman M.J., Emmerson E., Clarke L., Ashcroft G.S. Selective estrogen receptor modulators accelerate cutaneous wound healing in ovariectomised female mice. Endocrinology 2007.
    • (2007) Endocrinology
    • Hardman, M.J.1    Emmerson, E.2    Clarke, L.3    Ashcroft, G.S.4
  • 64
    • 0035097033 scopus 로고    scopus 로고
    • Longitudinal effects of aging on serum total and free testosterone levels in healthy men. Baltimore Longitudinal Study of Aging
    • Harman S.M., Metter E.J., Tobin J.D., Pearson J., Blackman M.R. Longitudinal effects of aging on serum total and free testosterone levels in healthy men. Baltimore Longitudinal Study of Aging. J. Clin. Endocrinol. Metab. 2001, 86:724-731.
    • (2001) J. Clin. Endocrinol. Metab. , vol.86 , pp. 724-731
    • Harman, S.M.1    Metter, E.J.2    Tobin, J.D.3    Pearson, J.4    Blackman, M.R.5
  • 65
    • 0034718549 scopus 로고    scopus 로고
    • Identification of a third distinct estrogen receptor and reclassification of estrogen receptors in teleosts
    • Hawkins M.B., Thornton J.W., Crews D., Skipper J.K., Dotte A., Thomas P. Identification of a third distinct estrogen receptor and reclassification of estrogen receptors in teleosts. Proc. Natl. Acad. Sci. USA 2000, 97:10751-10756.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 10751-10756
    • Hawkins, M.B.1    Thornton, J.W.2    Crews, D.3    Skipper, J.K.4    Dotte, A.5    Thomas, P.6
  • 66
    • 50549218525 scopus 로고
    • The limited in vitro lifetime of human diploid cell strains
    • Hayflick L. The limited in vitro lifetime of human diploid cell strains. Exp. Cell Res. 1965, 37:614-636.
    • (1965) Exp. Cell Res. , vol.37 , pp. 614-636
    • Hayflick, L.1
  • 67
    • 0030818060 scopus 로고    scopus 로고
    • Estrogen, cognition, and a woman's risk of Alzheimer's disease
    • Henderson V.W. Estrogen, cognition, and a woman's risk of Alzheimer's disease. Am. J. Med. 1997, 103:11S-18S.
    • (1997) Am. J. Med. , vol.103
    • Henderson, V.W.1
  • 69
    • 57449092483 scopus 로고    scopus 로고
    • IGF-I gene delivery promotes corticospinal neuronal survival but not regeneration after adult CNS injury
    • Hollis E.R., Lu P., Blesch A., Tuszynski M.H. IGF-I gene delivery promotes corticospinal neuronal survival but not regeneration after adult CNS injury. Exp. Neurol. 2009, 215:53-59.
    • (2009) Exp. Neurol. , vol.215 , pp. 53-59
    • Hollis, E.R.1    Lu, P.2    Blesch, A.3    Tuszynski, M.H.4
  • 72
    • 0027938567 scopus 로고
    • Demonstration of CRP immunoreactivity in brains of Alzheimer's disease: immunohistochemical study using formic acid pretreatment of tissue sections
    • Iwamoto N., Nishiyama E., Ohwada J., Arai H. Demonstration of CRP immunoreactivity in brains of Alzheimer's disease: immunohistochemical study using formic acid pretreatment of tissue sections. Neurosci. Lett. 1994, 177:23-26.
    • (1994) Neurosci. Lett. , vol.177 , pp. 23-26
    • Iwamoto, N.1    Nishiyama, E.2    Ohwada, J.3    Arai, H.4
  • 73
    • 0028342424 scopus 로고
    • Estrogen regulates metabolism of Alzheimer amyloid beta precursor protein
    • Jaffe A.B., Toran-Allerand C.D., Greengard P., Gandy S.E. Estrogen regulates metabolism of Alzheimer amyloid beta precursor protein. J. Biol. Chem. 1994, 269:13065-13068.
    • (1994) J. Biol. Chem. , vol.269 , pp. 13065-13068
    • Jaffe, A.B.1    Toran-Allerand, C.D.2    Greengard, P.3    Gandy, S.E.4
  • 75
    • 0032490591 scopus 로고    scopus 로고
    • Initiation and propagation stages of beta-amyloid are associated with distinctive apolipoprotein E, age, and gender profiles
    • Johnson J.K., McCleary R., Oshita M.H., Cotman C.W. Initiation and propagation stages of beta-amyloid are associated with distinctive apolipoprotein E, age, and gender profiles. Brain Res. 1998, 798:18-24.
    • (1998) Brain Res. , vol.798 , pp. 18-24
    • Johnson, J.K.1    McCleary, R.2    Oshita, M.H.3    Cotman, C.W.4
  • 76
    • 9444271646 scopus 로고    scopus 로고
    • Alzheimer's disease skin fibroblasts selectively express a bradykinin signaling pathway mediating tau protein Ser phosphorylation
    • Jong Y.J., Ford S.R., Seehra K., Malave V.B., Baenziger N.L. Alzheimer's disease skin fibroblasts selectively express a bradykinin signaling pathway mediating tau protein Ser phosphorylation. FASEB J. 2003, 17:2319-2321.
    • (2003) FASEB J. , vol.17 , pp. 2319-2321
    • Jong, Y.J.1    Ford, S.R.2    Seehra, K.3    Malave, V.B.4    Baenziger, N.L.5
  • 77
    • 15744380577 scopus 로고    scopus 로고
    • Regulatory roles of sex hormones in cutaneous biology and immunology
    • Kanda N., Watanabe S. Regulatory roles of sex hormones in cutaneous biology and immunology. J. Dermatol. Sci. 2005, 38:1-7.
    • (2005) J. Dermatol. Sci. , vol.38 , pp. 1-7
    • Kanda, N.1    Watanabe, S.2
  • 78
    • 1242299775 scopus 로고    scopus 로고
    • The role of telomeres in skin aging/photoaging
    • Kosmadaki M.G., Gilchrest B.A. The role of telomeres in skin aging/photoaging. Micron 2004, 35:155-159.
    • (2004) Micron , vol.35 , pp. 155-159
    • Kosmadaki, M.G.1    Gilchrest, B.A.2
  • 80
    • 0032076761 scopus 로고    scopus 로고
    • DHEA and the intracrine formation of androgens and estrogens in peripheral target tissues: its role during aging
    • Labrie F., Belanger A., Luu-The V., Labrie C., Simard J., Cusan L., Gomez J.L., Candas B. DHEA and the intracrine formation of androgens and estrogens in peripheral target tissues: its role during aging. Steroids 1998, 63:322-328.
    • (1998) Steroids , vol.63 , pp. 322-328
    • Labrie, F.1    Belanger, A.2    Luu-The, V.3    Labrie, C.4    Simard, J.5    Cusan, L.6    Gomez, J.L.7    Candas, B.8
  • 81
    • 11044228316 scopus 로고    scopus 로고
    • Do deficiencies in growth hormone and insulin-like growth factor-1 (IGF-1) shorten or prolong longevity?
    • Laron Z. Do deficiencies in growth hormone and insulin-like growth factor-1 (IGF-1) shorten or prolong longevity?. Mech. Ageing Dev. 2005, 126:305-307.
    • (2005) Mech. Ageing Dev. , vol.126 , pp. 305-307
    • Laron, Z.1
  • 82
    • 0034212151 scopus 로고    scopus 로고
    • Effects of dehydroepiandrosterone on collagen and collagenase gene expression by skin fibroblasts in culture
    • Lee K.S., Oh K.Y., Kim B.C. Effects of dehydroepiandrosterone on collagen and collagenase gene expression by skin fibroblasts in culture. J. Dermatol. Sci. 2000, 23:103-110.
    • (2000) J. Dermatol. Sci. , vol.23 , pp. 103-110
    • Lee, K.S.1    Oh, K.Y.2    Kim, B.C.3
  • 84
    • 77949424290 scopus 로고    scopus 로고
    • The IGF-1/IGF-1 R signaling axis in the skin: a new role for the dermis in aging-associated skin cancer
    • Lewis D.A., Travers J.B., Somani A.K., Spandau D.F. The IGF-1/IGF-1 R signaling axis in the skin: a new role for the dermis in aging-associated skin cancer. Oncogene 2010, 29:1475-1485.
    • (2010) Oncogene , vol.29 , pp. 1475-1485
    • Lewis, D.A.1    Travers, J.B.2    Somani, A.K.3    Spandau, D.F.4
  • 85
    • 0037336701 scopus 로고    scopus 로고
    • Interleukin-1 mediates pathological effects of microglia on tau phosphorylation and on synaptophysin synthesis in cortical neurons through a p38-MAPK pathway
    • Li Y., Liu L., Barger S.W., Griffin W.S. Interleukin-1 mediates pathological effects of microglia on tau phosphorylation and on synaptophysin synthesis in cortical neurons through a p38-MAPK pathway. J. Neurosci. 2003, 23:1605-1611.
    • (2003) J. Neurosci. , vol.23 , pp. 1605-1611
    • Li, Y.1    Liu, L.2    Barger, S.W.3    Griffin, W.S.4
  • 86
    • 1142275269 scopus 로고    scopus 로고
    • Age-related changes in lymphocyte development and function
    • Linton P.J., Dorshkind K. Age-related changes in lymphocyte development and function. Nat. Immunol. 2004, 5:133-139.
    • (2004) Nat. Immunol. , vol.5 , pp. 133-139
    • Linton, P.J.1    Dorshkind, K.2
  • 87
    • 0021861330 scopus 로고
    • Estradiol increases choline acetyltransferase activity in specific basal forebrain nuclei and projection areas of female rats
    • Luine V.N. Estradiol increases choline acetyltransferase activity in specific basal forebrain nuclei and projection areas of female rats. Exp. Neurol. 1985, 89:484-490.
    • (1985) Exp. Neurol. , vol.89 , pp. 484-490
    • Luine, V.N.1
  • 88
    • 0028596087 scopus 로고
    • Sex hormone modulation of neural development in vitro
    • Lustig R.H. Sex hormone modulation of neural development in vitro. Horm. Behav. 1994, 28:383-395.
    • (1994) Horm. Behav. , vol.28 , pp. 383-395
    • Lustig, R.H.1
  • 90
    • 34247540771 scopus 로고    scopus 로고
    • William J. Cunliffe Scientific Awards. Characteristics and pathomechanisms of endogenously aged skin
    • Makrantonaki E., Zouboulis C.C. William J. Cunliffe Scientific Awards. Characteristics and pathomechanisms of endogenously aged skin. Dermatology 2007, 214:352-360.
    • (2007) Dermatology , vol.214 , pp. 352-360
    • Makrantonaki, E.1    Zouboulis, C.C.2
  • 91
    • 33846953513 scopus 로고    scopus 로고
    • Testosterone metabolism to 5alpha-dihydrotestosterone and synthesis of sebaceous lipids is regulated by the peroxisome proliferator-activated receptor ligand linoleic acid in human sebocytes
    • Makrantonaki E., Zouboulis C.C. Testosterone metabolism to 5alpha-dihydrotestosterone and synthesis of sebaceous lipids is regulated by the peroxisome proliferator-activated receptor ligand linoleic acid in human sebocytes. Br. J. Dermatol. 2007, 156:428-432.
    • (2007) Br. J. Dermatol. , vol.156 , pp. 428-432
    • Makrantonaki, E.1    Zouboulis, C.C.2
  • 92
    • 36548999329 scopus 로고    scopus 로고
    • Molecular mechanisms of skin aging: state of the art
    • Makrantonaki E., Zouboulis C.C. Molecular mechanisms of skin aging: state of the art. Ann. NY Acad. Sci. 2007, 1119:40-50.
    • (2007) Ann. NY Acad. Sci. , vol.1119 , pp. 40-50
    • Makrantonaki, E.1    Zouboulis, C.C.2
  • 95
    • 53049086370 scopus 로고    scopus 로고
    • Interplay of IGF-I and 17beta-estradiol at age-specific levels in human sebocytes and fibroblasts in vitro
    • Makrantonaki E., Vogel K., Fimmel S., Oeff M., Seltmann H., Zouboulis C.C. Interplay of IGF-I and 17beta-estradiol at age-specific levels in human sebocytes and fibroblasts in vitro. Exp. Gerontol. 2008, 43:939-946.
    • (2008) Exp. Gerontol. , vol.43 , pp. 939-946
    • Makrantonaki, E.1    Vogel, K.2    Fimmel, S.3    Oeff, M.4    Seltmann, H.5    Zouboulis, C.C.6
  • 97
    • 0031685620 scopus 로고    scopus 로고
    • TGF-beta signal transduction
    • Massague J. TGF-beta signal transduction. Annu. Rev. Biochem. 1998, 67:753-791.
    • (1998) Annu. Rev. Biochem. , vol.67 , pp. 753-791
    • Massague, J.1
  • 98
    • 0027377415 scopus 로고
    • Insulin-like growth factor I receptors and IGF-I actions in neuronal cultures from the brain
    • Masters B.A., Raizada M.K. Insulin-like growth factor I receptors and IGF-I actions in neuronal cultures from the brain. Ann. NY Acad. Sci. 1993, 692:89-101.
    • (1993) Ann. NY Acad. Sci. , vol.692 , pp. 89-101
    • Masters, B.A.1    Raizada, M.K.2
  • 99
    • 0021942128 scopus 로고
    • De novo sterologenesis in the skin. II. Regulation by cutaneous barrier requirements
    • Menon G.K., Feingold K.R., Moser A.H., Brown B.E., Elias P.M. De novo sterologenesis in the skin. II. Regulation by cutaneous barrier requirements. J. Lipid Res. 1985, 26:418-427.
    • (1985) J. Lipid Res. , vol.26 , pp. 418-427
    • Menon, G.K.1    Feingold, K.R.2    Moser, A.H.3    Brown, B.E.4    Elias, P.M.5
  • 100
    • 0033595684 scopus 로고    scopus 로고
    • Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication
    • Michikawa Y., Mazzucchelli F., Bresolin N., Scarlato G., Attardi G. Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication. Science 1999, 286:774-779.
    • (1999) Science , vol.286 , pp. 774-779
    • Michikawa, Y.1    Mazzucchelli, F.2    Bresolin, N.3    Scarlato, G.4    Attardi, G.5
  • 101
    • 0031964919 scopus 로고    scopus 로고
    • An update on the oxygen stress-mitochondrial mutation theory of aging: genetic and evolutionary implications
    • Miquel J. An update on the oxygen stress-mitochondrial mutation theory of aging: genetic and evolutionary implications. Exp. Gerontol. 1998, 33:113-126.
    • (1998) Exp. Gerontol. , vol.33 , pp. 113-126
    • Miquel, J.1
  • 103
    • 0027345755 scopus 로고
    • Mechanisms of age-related endocrine alterations. Part I
    • Mooradian A.D. Mechanisms of age-related endocrine alterations. Part I. Drugs Aging 1993, 3:81-97.
    • (1993) Drugs Aging , vol.3 , pp. 81-97
    • Mooradian, A.D.1
  • 104
    • 3042533413 scopus 로고    scopus 로고
    • The choice between epidermal and neural fate: a matter of calcium
    • Moreau M., Leclerc C. The choice between epidermal and neural fate: a matter of calcium. Int. J. Dev. Biol. 2004, 48:75-84.
    • (2004) Int. J. Dev. Biol. , vol.48 , pp. 75-84
    • Moreau, M.1    Leclerc, C.2
  • 105
    • 0026907151 scopus 로고
    • A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid
    • Mullan M., Crawford F., Axelman K., Houlden H., Lilius L., Winblad B., Lannfelt L. A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid. Nat. Genet. 1992, 1:345-347.
    • (1992) Nat. Genet. , vol.1 , pp. 345-347
    • Mullan, M.1    Crawford, F.2    Axelman, K.3    Houlden, H.4    Lilius, L.5    Winblad, B.6    Lannfelt, L.7
  • 106
    • 0032712557 scopus 로고    scopus 로고
    • Decreased plasma insulin-like growth factor-I level in familial Alzheimer's disease patients carrying the Swedish APP 670/671 mutation
    • Mustafa A., Lannfelt L., Lilius L., Islam A., Winblad B., Adem A. Decreased plasma insulin-like growth factor-I level in familial Alzheimer's disease patients carrying the Swedish APP 670/671 mutation. Dement. Geriatr. Cogn. Disord. 1999, 10:446-451.
    • (1999) Dement. Geriatr. Cogn. Disord. , vol.10 , pp. 446-451
    • Mustafa, A.1    Lannfelt, L.2    Lilius, L.3    Islam, A.4    Winblad, B.5    Adem, A.6
  • 108
    • 0028969073 scopus 로고
    • Long-term estrogen replacement therapy in female patients with dementia of the Alzheimer type: 7 case reports
    • Ohkura T., Isse K., Akazawa K., Hamamoto M., Yaoi Y., Hagino N. Long-term estrogen replacement therapy in female patients with dementia of the Alzheimer type: 7 case reports. Dementia 1995, 6:99-107.
    • (1995) Dementia , vol.6 , pp. 99-107
    • Ohkura, T.1    Isse, K.2    Akazawa, K.3    Hamamoto, M.4    Yaoi, Y.5    Hagino, N.6
  • 109
    • 0021181906 scopus 로고
    • Age changes and sex differences in serum dehydroepiandrosterone sulfate concentrations throughout adulthood
    • Orentreich N., Brind J.L., Rizer R.L., Vogelman J.H. Age changes and sex differences in serum dehydroepiandrosterone sulfate concentrations throughout adulthood. J. Clin. Endocrinol. Metab. 1984, 59:551-555.
    • (1984) J. Clin. Endocrinol. Metab. , vol.59 , pp. 551-555
    • Orentreich, N.1    Brind, J.L.2    Rizer, R.L.3    Vogelman, J.H.4
  • 114
    • 0033625861 scopus 로고    scopus 로고
    • Ovariectomy and 17beta-estradiol modulate the levels of Alzheimer's amyloid beta peptides in brain
    • Petanceska S.S., Nagy V., Frail D., Gandy S. Ovariectomy and 17beta-estradiol modulate the levels of Alzheimer's amyloid beta peptides in brain. Exp. Gerontol. 2000, 35:1317-1325.
    • (2000) Exp. Gerontol. , vol.35 , pp. 1317-1325
    • Petanceska, S.S.1    Nagy, V.2    Frail, D.3    Gandy, S.4
  • 115
    • 48749092346 scopus 로고    scopus 로고
    • Does hormone therapy improve age-related skin changes in postmenopausal women? A randomized, double-blind, double-dummy, placebo-controlled multicenter study assessing the effects of norethindrone acetate and ethinyl estradiol in the improvement of mild to moderate age-related skin changes in postmenopausal women
    • Phillips T.J., Symons J., Menon S. Does hormone therapy improve age-related skin changes in postmenopausal women? A randomized, double-blind, double-dummy, placebo-controlled multicenter study assessing the effects of norethindrone acetate and ethinyl estradiol in the improvement of mild to moderate age-related skin changes in postmenopausal women. J. Am. Acad. Dermatol. 2008, 59(397-404):e3.
    • (2008) J. Am. Acad. Dermatol. , vol.59 , Issue.397-404
    • Phillips, T.J.1    Symons, J.2    Menon, S.3
  • 119
    • 0023074424 scopus 로고
    • Local oestriol treatment improves the structure of elastic fibers in the skin of postmenopausal women
    • Punnonen R., Vaajalahti P., Teisala K. Local oestriol treatment improves the structure of elastic fibers in the skin of postmenopausal women. Ann. Chir. Gynaecol. Suppl. 1987, 202:39-41.
    • (1987) Ann. Chir. Gynaecol. Suppl. , vol.202 , pp. 39-41
    • Punnonen, R.1    Vaajalahti, P.2    Teisala, K.3
  • 122
    • 51949096280 scopus 로고    scopus 로고
    • Induction of collagen by estradiol: difference between sun-protected and photodamaged human skin in vivo
    • Rittie L., Kang S., Voorhees J.J., Fisher G.J. Induction of collagen by estradiol: difference between sun-protected and photodamaged human skin in vivo. Arch. Dermatol. 2008, 144:1129-1140.
    • (2008) Arch. Dermatol. , vol.144 , pp. 1129-1140
    • Rittie, L.1    Kang, S.2    Voorhees, J.J.3    Fisher, G.J.4
  • 124
    • 73449091835 scopus 로고    scopus 로고
    • Mecasermin (recombinant human insulin-like growth factor I)
    • Rosenbloom A.L. Mecasermin (recombinant human insulin-like growth factor I). Adv. Ther. 2009, 26:40-54.
    • (2009) Adv. Ther. , vol.26 , pp. 40-54
    • Rosenbloom, A.L.1
  • 125
  • 128
    • 33846874575 scopus 로고    scopus 로고
    • The role of the IGF system in cancer growth and metastasis: overview and recent insights
    • Samani A.A., Yakar S., LeRoith D., Brodt P. The role of the IGF system in cancer growth and metastasis: overview and recent insights. Endocr. Rev. 2007, 28:20-47.
    • (2007) Endocr. Rev. , vol.28 , pp. 20-47
    • Samani, A.A.1    Yakar, S.2    LeRoith, D.3    Brodt, P.4
  • 129
    • 0035948752 scopus 로고    scopus 로고
    • The influence of hormone replacement therapy on skin ageing: a pilot study
    • Sator P.G., Schmidt J.B., Sator M.O., Huber J.C., Honigsmann H. The influence of hormone replacement therapy on skin ageing: a pilot study. Maturitas 2001, 39:43-55.
    • (2001) Maturitas , vol.39 , pp. 43-55
    • Sator, P.G.1    Schmidt, J.B.2    Sator, M.O.3    Huber, J.C.4    Honigsmann, H.5
  • 130
    • 34547216488 scopus 로고    scopus 로고
    • A prospective, randomized, double-blind, placebo-controlled study on the influence of a hormone replacement therapy on skin aging in postmenopausal women
    • Sator P.G., Sator M.O., Schmidt J.B., Nahavandi H., Radakovic S., Huber J.C., Honigsmann H. A prospective, randomized, double-blind, placebo-controlled study on the influence of a hormone replacement therapy on skin aging in postmenopausal women. Climacteric 2007, 10:320-334.
    • (2007) Climacteric , vol.10 , pp. 320-334
    • Sator, P.G.1    Sator, M.O.2    Schmidt, J.B.3    Nahavandi, H.4    Radakovic, S.5    Huber, J.C.6    Honigsmann, H.7
  • 132
    • 33645982478 scopus 로고    scopus 로고
    • Perspectives of estrogen treatment in skin aging
    • Schmidt J.B. Perspectives of estrogen treatment in skin aging. Exp. Dermatol. 2005, 14:156.
    • (2005) Exp. Dermatol. , vol.14 , pp. 156
    • Schmidt, J.B.1
  • 133
    • 0001068487 scopus 로고
    • The relationship between in vitro cellular aging and in vivo human age
    • Schneider E.L., Mitsui Y. The relationship between in vitro cellular aging and in vivo human age. Proc. Natl. Acad. Sci. USA 1976, 73:3584-3588.
    • (1976) Proc. Natl. Acad. Sci. USA , vol.73 , pp. 3584-3588
    • Schneider, E.L.1    Mitsui, Y.2
  • 136
    • 27744481762 scopus 로고    scopus 로고
    • Prevalence and natural course of aging-associated cognitive decline in a population-based sample of young-old subjects
    • Schonknecht P., Pantel J., Kruse A., Schroder J. Prevalence and natural course of aging-associated cognitive decline in a population-based sample of young-old subjects. Am. J. Psychiatry 2005, 162:2071-2077.
    • (2005) Am. J. Psychiatry , vol.162 , pp. 2071-2077
    • Schonknecht, P.1    Pantel, J.2    Kruse, A.3    Schroder, J.4
  • 137
    • 33947206696 scopus 로고    scopus 로고
    • Increased tau protein differentiates mild cognitive impairment from geriatric depression and predicts conversion to dementia
    • Schonknecht P., Pantel J., Kaiser E., Thomann P., Schroder J. Increased tau protein differentiates mild cognitive impairment from geriatric depression and predicts conversion to dementia. Neurosci. Lett. 2007, 416:39-42.
    • (2007) Neurosci. Lett. , vol.416 , pp. 39-42
    • Schonknecht, P.1    Pantel, J.2    Kaiser, E.3    Thomann, P.4    Schroder, J.5
  • 138
    • 58149260966 scopus 로고    scopus 로고
    • Growth hormone secretagogue MK-677: no clinical effect on AD progression in a randomized trial
    • Sevigny J.J., Ryan J.M., van Dyck C.H., Peng Y., Lines C.R., Nessly M.L. Growth hormone secretagogue MK-677: no clinical effect on AD progression in a randomized trial. Neurology 2008, 71:1702-1708.
    • (2008) Neurology , vol.71 , pp. 1702-1708
    • Sevigny, J.J.1    Ryan, J.M.2    van Dyck, C.H.3    Peng, Y.4    Lines, C.R.5    Nessly, M.L.6
  • 139
    • 12944273425 scopus 로고    scopus 로고
    • Modulation of collagen metabolism by the topical application of dehydroepiandrosterone to human skin
    • Shin M.H., Rhie G.E., Park C.H., Kim K.H., Cho K.H., Eun H.C., Chung J.H. Modulation of collagen metabolism by the topical application of dehydroepiandrosterone to human skin. J. Invest. Dermatol. 2005, 124:315-323.
    • (2005) J. Invest. Dermatol. , vol.124 , pp. 315-323
    • Shin, M.H.1    Rhie, G.E.2    Park, C.H.3    Kim, K.H.4    Cho, K.H.5    Eun, H.C.6    Chung, J.H.7
  • 141
    • 34347238198 scopus 로고    scopus 로고
    • Genetics of human longevity with emphasis on the relevance of HSP70 as candidate genes
    • Singh R., Kolvraa S., Rattan S.I. Genetics of human longevity with emphasis on the relevance of HSP70 as candidate genes. Front. Biosci. 2007, 12:4504-4513.
    • (2007) Front. Biosci. , vol.12 , pp. 4504-4513
    • Singh, R.1    Kolvraa, S.2    Rattan, S.I.3
  • 142
    • 0030038104 scopus 로고    scopus 로고
    • Replicative senescence: implications for in vivo aging and tumor suppression
    • Smith J.R., Pereira-Smith O.M. Replicative senescence: implications for in vivo aging and tumor suppression. Science 1996, 273:63-67.
    • (1996) Science , vol.273 , pp. 63-67
    • Smith, J.R.1    Pereira-Smith, O.M.2
  • 143
    • 0028226510 scopus 로고
    • Effect of inhibin immunoneutralization on steroidogenesis in rat ovarian follicles in vitro
    • Smyth C.D., Gosden R.G., McNeilly A.S., Hillier S.G. Effect of inhibin immunoneutralization on steroidogenesis in rat ovarian follicles in vitro. J. Endocrinol. 1994, 140:437-443.
    • (1994) J. Endocrinol. , vol.140 , pp. 437-443
    • Smyth, C.D.1    Gosden, R.G.2    McNeilly, A.S.3    Hillier, S.G.4
  • 144
    • 0031804642 scopus 로고    scopus 로고
    • The activity of HMG-CoA reductase and acetyl-CoA carboxylase in human apocrine sweat glands, sebaceous glands, and hair follicles is regulated by phosphorylation and by exogenous cholesterol
    • Smythe C.D., Greenall M., Kealey T. The activity of HMG-CoA reductase and acetyl-CoA carboxylase in human apocrine sweat glands, sebaceous glands, and hair follicles is regulated by phosphorylation and by exogenous cholesterol. J. Invest. Dermatol. 1998, 111:139-148.
    • (1998) J. Invest. Dermatol. , vol.111 , pp. 139-148
    • Smythe, C.D.1    Greenall, M.2    Kealey, T.3
  • 145
    • 2442707519 scopus 로고    scopus 로고
    • Effects of aging and postmenopausal hypoestrogenism on skin elasticity and bone mineral density in Japanese women
    • Sumino H., Ichikawa S., Abe M., Endo Y., Nakajima Y., Minegishi T., Ishikawa O., Kurabayashi M. Effects of aging and postmenopausal hypoestrogenism on skin elasticity and bone mineral density in Japanese women. Endocr. J. 2004, 51:159-164.
    • (2004) Endocr. J. , vol.51 , pp. 159-164
    • Sumino, H.1    Ichikawa, S.2    Abe, M.3    Endo, Y.4    Nakajima, Y.5    Minegishi, T.6    Ishikawa, O.7    Kurabayashi, M.8
  • 147
    • 77953827925 scopus 로고    scopus 로고
    • Inflammation in the Alzheimer's disease cascade: culprit or innocent bystander?
    • Tan Z.S., Seshadri S. Inflammation in the Alzheimer's disease cascade: culprit or innocent bystander?. Alzheimers Res. Ther. 2010, 2:6.
    • (2010) Alzheimers Res. Ther. , vol.2 , pp. 6
    • Tan, Z.S.1    Seshadri, S.2
  • 151
    • 0033497525 scopus 로고    scopus 로고
    • Maintenance of human skin in organ culture: role for insulin-like growth factor-1 receptor and epidermal growth factor receptor
    • Tavakkol A., Varani J., Elder J.T., Zouboulis C.C. Maintenance of human skin in organ culture: role for insulin-like growth factor-1 receptor and epidermal growth factor receptor. Arch. Dermatol. Res. 1999, 291:643-651.
    • (1999) Arch. Dermatol. Res. , vol.291 , pp. 643-651
    • Tavakkol, A.1    Varani, J.2    Elder, J.T.3    Zouboulis, C.C.4
  • 152
    • 0023922851 scopus 로고
    • Insulin-like growth factors and somatomedin B in the cerebrospinal fluid of patients with dementia of the Alzheimer type
    • Tham A., Sparring K., Bowen D., Wetterberg L., Sara V.R. Insulin-like growth factors and somatomedin B in the cerebrospinal fluid of patients with dementia of the Alzheimer type. Acta Psychiatr. Scand. 1988, 77:719-723.
    • (1988) Acta Psychiatr. Scand. , vol.77 , pp. 719-723
    • Tham, A.1    Sparring, K.2    Bowen, D.3    Wetterberg, L.4    Sara, V.R.5
  • 154
    • 33747374579 scopus 로고    scopus 로고
    • The modulation of aromatase and estrogen receptor alpha in cultured human dermal papilla cells by dexamethasone: a novel mechanism for selective action of estrogen via estrogen receptor beta?
    • Thornton M.J., Nelson L.D., Taylor A.H., Birch M.P., Laing I., Messenger A.G. The modulation of aromatase and estrogen receptor alpha in cultured human dermal papilla cells by dexamethasone: a novel mechanism for selective action of estrogen via estrogen receptor beta?. J. Invest. Dermatol. 2006, 126:2010-2018.
    • (2006) J. Invest. Dermatol. , vol.126 , pp. 2010-2018
    • Thornton, M.J.1    Nelson, L.D.2    Taylor, A.H.3    Birch, M.P.4    Laing, I.5    Messenger, A.G.6
  • 156
    • 33947513279 scopus 로고    scopus 로고
    • Modulation of replicative senescence of diploid human cells by nuclear ERK signaling
    • Tresini M., Lorenzini A., Torres C., Cristofalo V.J. Modulation of replicative senescence of diploid human cells by nuclear ERK signaling. J. Biol. Chem. 2007, 282:4136-4151.
    • (2007) J. Biol. Chem. , vol.282 , pp. 4136-4151
    • Tresini, M.1    Lorenzini, A.2    Torres, C.3    Cristofalo, V.J.4
  • 157
  • 159
    • 33745996107 scopus 로고    scopus 로고
    • Identification of a mutant-like conformation of p53 in fibroblasts from sporadic Alzheimer's disease patients
    • Uberti D., Lanni C., Carsana T., Francisconi S., Missale C., Racchi M., Govoni S., Memo M. Identification of a mutant-like conformation of p53 in fibroblasts from sporadic Alzheimer's disease patients. Neurobiol. Aging 2006, 27:1193-1201.
    • (2006) Neurobiol. Aging , vol.27 , pp. 1193-1201
    • Uberti, D.1    Lanni, C.2    Carsana, T.3    Francisconi, S.4    Missale, C.5    Racchi, M.6    Govoni, S.7    Memo, M.8
  • 160
    • 0030334820 scopus 로고    scopus 로고
    • Effect of estrogen replacement therapy on hepatic triglyceride lipase, lipoprotein lipase and lipids including apolipoprotein E in climacteric and elderly women
    • Urabe M., Yamamoto T., Kashiwagi T., Okubo T., Tsuchiya H., Iwasa K., Kikuchi N., Yokota K., Hosokawa K., Honjo H. Effect of estrogen replacement therapy on hepatic triglyceride lipase, lipoprotein lipase and lipids including apolipoprotein E in climacteric and elderly women. Endocr. J. 1996, 43:737-742.
    • (1996) Endocr. J. , vol.43 , pp. 737-742
    • Urabe, M.1    Yamamoto, T.2    Kashiwagi, T.3    Okubo, T.4    Tsuchiya, H.5    Iwasa, K.6    Kikuchi, N.7    Yokota, K.8    Hosokawa, K.9    Honjo, H.10
  • 163
    • 0037468342 scopus 로고    scopus 로고
    • Can growth hormone prevent aging?
    • Vance M.L. Can growth hormone prevent aging?. N. Engl. J. Med. 2003, 348:779-780.
    • (2003) N. Engl. J. Med. , vol.348 , pp. 779-780
    • Vance, M.L.1
  • 164
    • 1642401412 scopus 로고    scopus 로고
    • Estradiol supplementation modulates growth hormone (GH) secretory-burst waveform and recombinant human insulin-like growth factor-I-enforced suppression of endogenously driven GH release in postmenopausal women
    • Veldhuis J.D., Anderson S.M., Kok P., Iranmanesh A., Frystyk J., Orskov H., Keenan D.M. Estradiol supplementation modulates growth hormone (GH) secretory-burst waveform and recombinant human insulin-like growth factor-I-enforced suppression of endogenously driven GH release in postmenopausal women. J. Clin. Endocrinol. Metab. 2004, 89:1312-1318.
    • (2004) J. Clin. Endocrinol. Metab. , vol.89 , pp. 1312-1318
    • Veldhuis, J.D.1    Anderson, S.M.2    Kok, P.3    Iranmanesh, A.4    Frystyk, J.5    Orskov, H.6    Keenan, D.M.7
  • 166
    • 0036901234 scopus 로고    scopus 로고
    • Cytokines and cognition-the case for a head-to-toe inflammatory paradigm
    • Wilson C.J., Finch C.E., Cohen H.J. Cytokines and cognition-the case for a head-to-toe inflammatory paradigm. J. Am. Geriatr. Soc. 2002, 50:2041-2056.
    • (2002) J. Am. Geriatr. Soc. , vol.50 , pp. 2041-2056
    • Wilson, C.J.1    Finch, C.E.2    Cohen, H.J.3
  • 167
    • 0027987251 scopus 로고
    • Estradiol regulates hippocampal dendritic spine density via an N-methyl-d-aspartate receptor-dependent mechanism
    • Woolley C.S., McEwen B.S. Estradiol regulates hippocampal dendritic spine density via an N-methyl-d-aspartate receptor-dependent mechanism. J. Neurosci. 1994, 14:7680-7687.
    • (1994) J. Neurosci. , vol.14 , pp. 7680-7687
    • Woolley, C.S.1    McEwen, B.S.2
  • 169
    • 0030750476 scopus 로고    scopus 로고
    • Human melanocytes as a model system for studies of Alzheimer disease
    • Yaar M., Gilchrest B.A. Human melanocytes as a model system for studies of Alzheimer disease. Arch. Dermatol. 1997, 133:1287-1291.
    • (1997) Arch. Dermatol. , vol.133 , pp. 1287-1291
    • Yaar, M.1    Gilchrest, B.A.2
  • 170
    • 0032481568 scopus 로고    scopus 로고
    • Estrogen therapy in postmenopausal women: effects on cognitive function and dementia
    • Yaffe K., Sawaya G., Lieberburg I., Grady D. Estrogen therapy in postmenopausal women: effects on cognitive function and dementia. Jama 1998, 279:688-695.
    • (1998) Jama , vol.279 , pp. 688-695
    • Yaffe, K.1    Sawaya, G.2    Lieberburg, I.3    Grady, D.4
  • 171
    • 0036615233 scopus 로고    scopus 로고
    • Alterations in cytokine regulation in aged epidermis: implications for permeability barrier homeostasis and inflammation. I. IL-1 gene family
    • Ye J., Garg A., Calhoun C., Feingold K.R., Elias P.M., Ghadially R. Alterations in cytokine regulation in aged epidermis: implications for permeability barrier homeostasis and inflammation. I. IL-1 gene family. Exp. Dermatol. 2002, 11:209-216.
    • (2002) Exp. Dermatol. , vol.11 , pp. 209-216
    • Ye, J.1    Garg, A.2    Calhoun, C.3    Feingold, K.R.4    Elias, P.M.5    Ghadially, R.6
  • 172
    • 0034583277 scopus 로고    scopus 로고
    • Human skin: an independent peripheral endocrine organ
    • Zouboulis C.C. Human skin: an independent peripheral endocrine organ. Horm. Res. 2000, 54:230-242.
    • (2000) Horm. Res. , vol.54 , pp. 230-242
    • Zouboulis, C.C.1
  • 173
    • 0042818328 scopus 로고    scopus 로고
    • Intrinsic skin aging. A critical appraisal of the role of hormones
    • Zouboulis Ch C. Intrinsic skin aging. A critical appraisal of the role of hormones. Hautarzt 2003, 54:825-832.
    • (2003) Hautarzt , vol.54 , pp. 825-832
    • Zouboulis Ch, C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.