Longwave UV light induces the aging-associated progerin

Journal of Investigative Dermatology

Volumn 133, Issue 7, 2013, Pages 1857-1862

  Takeuchi, Hirotaka ^a,b   Rünger, Thomas M ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b POLA CHEMICAL INDUSTRIES INC   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

LAMIN A; MESSENGER RNA; PROGERIN; SINGLET OXYGEN; SODIUM AZIDE; UNCLASSIFIED DRUG; UVAOL;

ALTERNATIVE RNA SPLICING; ARTICLE; BIOACCUMULATION; CONTROLLED STUDY; CUTANEOUS PARAMETERS; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; LIGHT; LMNA GENE; NUCLEAR SHAPE; OXIDATIVE STRESS; PHENOTYPE; PHOTOAGING; PRIORITY JOURNAL; PROGERIA; PROTEIN EXPRESSION; PROTEIN INDUCTION; SKIN FIBROBLAST; ULTRAVIOLET A RADIATION; ULTRAVIOLET B RADIATION; ULTRAVIOLET RADIATION;

EID: 84879413106     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2013.71     Document Type: Article

References (29)

1. Burtner CR, Kennedy BK (2010) Progeria syndromes and ageing: what is the connection? Nat Rev Mol Cell Biol 11:567-78
2. Busch A, Kiel T, Heupel WM et al. (2009) Nuclear protein import is reduced in cells expressing nuclear envelopathy-causing lamin A mutants. Exp Cell Res 315:2373-85
3. Cadet J, Douki T, Ravanat JL et al. (2009) Sensitized formation of oxidatively generated damage to cellular DNA by UVA radiation. Photochem Photobiol Sci 8:903-11
4. Chandler DS, Singh RK, Caldwell LC et al. (2006) Genotoxic stress induces coordinately regulated alternative splicing of the p53 modulators MDM2 and MDM4. Cancer Res 66:9502-8 (Pubitemid 44623648)
5. De Sandre-Giovannoli A, Bernard R, Cau P et al. (2003) Lamin a truncation in Hutchinson-Gilford progeria. Science 300:2055
6. Decker ML, Chavez E, Vulto I et al. (2009) Telomere length in Hutchinson-Gilford progeria syndrome. Mech Ageing Dev 130:377-83
7. Dong KK, Damaghi N, Picart SD et al. (2008) UV-induced DNA damage initiates release of MMP-1 in human skin. Exp Dermatol 17:1037-44
8. Eriksson M, Brown WT, Gordon LB et al. (2003) Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome. Nature 423:293-8 (Pubitemid 40852699)
9. Fagot D, Asselineau D, Bernerd F (2004) Matrix metalloproteinase-1 production observed after solar-simulated radiation exposure is assumed by dermal fibroblasts but involves a paracrine activation through epidermal keratinocytes. Photochem Photobiol 79:499-505
10. Ikehata H, Ono T (2011) The mechanisms of UV mutagenesis. J Radiat Res 52:115-25
11. Kappes UP, Luo D, Potter M et al. (2006) Short-and long-wave UV light (UVB and UVA) induce similar mutations in human skin cells. J Invest Dermatol 126:667-75 (Pubitemid 43255658)
12. Kosmadaki MG, Gilchrest BA (2004) The role of telomeres in skin aging/photoaging. Micron 35:155-9 (Pubitemid 38225240)
13. Krutmann J (2006) The interaction of UVA and UVB wavebands with particular emphasis on signalling. Prog Biophys Mol Biol 92:105-7 (Pubitemid 43831954)
14. Mazereeuw-Hautier J, Wilson LC, Mohammed S et al. (2007) Hutchinson-Gilford progeria syndrome: clinical findings in three patients carrying the G608G mutation in LMNA and review of the literature. Br J Dermatol 156:1308-14 (Pubitemid 47029832)
15. McClintock D, Ratner D, Lokuge M et al. (2007) The mutant form of lamin A that causes Hutchinson-Gilford progeria is a biomarker of cellular aging in human skin. PLoS One 2:e1269
16. Melnikova VO, Ananthaswamy HN (2005) Cellular and molecular events leading to the development of skin cancer. Mutat Res 571:91-106 (Pubitemid 40313435)
17. Munoz MJ, Pérez Santangelo MS, Paronetto MP et al. (2009) DNA damage regulates alternative splicing through inhibition of RNA polymerase II elongation. Cell 137:708-20
18. Musich PR, Zou Y (2009) Genomic instability and DNA damage responses in progeria arising from defective maturation of prelamin A. Aging (Albany NY) 1:28-37
19. Nicholls CD, Shields MA, Lee PW et al. (2004) UV-dependent alternative splicing uncouples p53 activity and PIG3 gene function through rapid proteolytic degradation. J Biol Chem 279:24171-8 (Pubitemid 38725277)
20. Nunomura A, Moreira PI, Castellani RJ et al. (2012) Oxidative damage to RNA in aging and neurodegenerative disorders. Neurotox Res 22:231-48
21. Paronetto MP, Miñana B, Valcárcel J (2011) The Ewing sarcoma protein regulates DNA damage-induced alternative splicing. Mol Cell 43:353-68
22. Ravanat JL, Douki T, Cadet J (2001) Direct and indirect effects of UV radiation on DNA and its components. J Photochem Photobiol B 63:88-102 (Pubitemid 33040727)
23. Rodriguez S, Coppedè F, Sagelius H et al. (2009) Increased expression of the Hutchinson-Gilford progeria syndrome truncated lamin A transcript during cell aging. Eur J Hum Genet 17:928-37
24. Rünger TM, Kappes UP (2008) Mechanisms of mutation formation with longwave ultraviolet light (UVA). Photodermatol Photoimmunol Photomed 24:2-10
25. Scaffidi P, Misteli T (2006) Lamin A-dependent nuclear defects in human aging. Science 312:1059-63
26. Sohal RS, Orr WC (2011) The redox stress hypothesis of aging. Free Radic Biol Med 52:539-55
27. Stanulis-Praeger BM, Gilchrest BA (1989) Effect of donor age and prior sun exposure on growth inhibition of cultured human dermal fibroblasts by all trans-retinoic acid. J Cell Physiol 139:116-24 (Pubitemid 19120278)
28. Uitto J (2008) The role of elastin and collagen in cutaneous aging: intrinsic aging versus photoexposure. J Drugs Dermatol 7:s12-6
29. Wlaschek M, Wenk J, Brenneisen P et al. (1997) Singlet oxygen is an early intermediate in cytokine-dependent ultraviolet-A induction of interstitial collagenase in human dermal fibroblasts in vitro. FEBS Lett 413:239-42 (Pubitemid 27353276)