-
1
-
-
67649739079
-
Iron toxicity in diseases of aging: Alzheimer's disease, Parkinson's disease and atherosclerosis
-
Altamura S., Muckenthaler M.U. Iron toxicity in diseases of aging: Alzheimer's disease, Parkinson's disease and atherosclerosis. J. Alzheimers Dis. 2009, 16(4):879-895.
-
(2009)
J. Alzheimers Dis.
, vol.16
, Issue.4
, pp. 879-895
-
-
Altamura, S.1
Muckenthaler, M.U.2
-
2
-
-
0042626242
-
SKN-1 links C. elegans mesendodermal specification to a conserved oxidative stress response
-
An J.H., Blackwell T.K. SKN-1 links C. elegans mesendodermal specification to a conserved oxidative stress response. Genes Dev. 2003, 17(15):1882-1893.
-
(2003)
Genes Dev.
, vol.17
, Issue.15
, pp. 1882-1893
-
-
An, J.H.1
Blackwell, T.K.2
-
3
-
-
34948911093
-
Reduced expression of the Caenorhabditis elegans p53 ortholog cep-1 results in increased longevity
-
Arum O., Johnson T.E. Reduced expression of the Caenorhabditis elegans p53 ortholog cep-1 results in increased longevity. J Gerontol A Biol Sci Med Sci 2007, 62(9):951-959.
-
(2007)
J Gerontol A Biol Sci Med Sci
, vol.62
, Issue.9
, pp. 951-959
-
-
Arum, O.1
Johnson, T.E.2
-
4
-
-
34249681337
-
P53: new roles in metabolism
-
Bensaad K., Vousden K.H. P53: new roles in metabolism. Trends Cell Biol. 2007, 17(6):286-291.
-
(2007)
Trends Cell Biol.
, vol.17
, Issue.6
, pp. 286-291
-
-
Bensaad, K.1
Vousden, K.H.2
-
5
-
-
24344448786
-
P53 isoforms can regulate p53 transcriptional activity
-
Bourdon J.C., Fernandes K., Murray-Zmijewski F., Liu G., Diot A., Xirodimas D.P., Saville M.K., Lane D.P. p53 isoforms can regulate p53 transcriptional activity. Genes Dev. 2005, 19(18):2122-2137.
-
(2005)
Genes Dev.
, vol.19
, Issue.18
, pp. 2122-2137
-
-
Bourdon, J.C.1
Fernandes, K.2
Murray-Zmijewski, F.3
Liu, G.4
Diot, A.5
Xirodimas, D.P.6
Saville, M.K.7
Lane, D.P.8
-
6
-
-
13344270899
-
Friedreich's ataxia: autosomal recessive disease caused by an intronic GAA triplet repeat expansion
-
Campuzano V., Montermini L., Molto M.D., Pianese L., Cossee M., Cavalcanti F., Monros E., Rodius F., Duclos F., Monticelli A., Zara F., Canizares J., Koutnikova H., Bidichandani S.I., Gellera C., Brice A., Trouillas P., De Michele G., Filla A., De Frutos R., Palau F., Patel P.I., Di Donato S., Mandel J.L., Cocozza S., Koenig M., Pandolfo M. Friedreich's ataxia: autosomal recessive disease caused by an intronic GAA triplet repeat expansion. Science 1996, 271(5254):1423-1427.
-
(1996)
Science
, vol.271
, Issue.5254
, pp. 1423-1427
-
-
Campuzano, V.1
Montermini, L.2
Molto, M.D.3
Pianese, L.4
Cossee, M.5
Cavalcanti, F.6
Monros, E.7
Rodius, F.8
Duclos, F.9
Monticelli, A.10
Zara, F.11
Canizares, J.12
Koutnikova, H.13
Bidichandani, S.I.14
Gellera, C.15
Brice, A.16
Trouillas, P.17
De Michele, G.18
Filla, A.19
De Frutos, R.20
Palau, F.21
Patel, P.I.22
Di Donato, S.23
Mandel, J.L.24
Cocozza, S.25
Koenig, M.26
Pandolfo, M.27
more..
-
7
-
-
67449128222
-
Direct interaction between Nrf2 and p21(Cip1/WAF1) upregulates the Nrf2-mediated antioxidant response
-
Chen W., Sun Z., Wang X.J., Jiang T., Huang Z., Fang D., Zhang D.D. Direct interaction between Nrf2 and p21(Cip1/WAF1) upregulates the Nrf2-mediated antioxidant response. Mol. Cell 2009, 34(6):663-673.
-
(2009)
Mol. Cell
, vol.34
, Issue.6
, pp. 663-673
-
-
Chen, W.1
Sun, Z.2
Wang, X.J.3
Jiang, T.4
Huang, Z.5
Fang, D.6
Zhang, D.D.7
-
8
-
-
33947356736
-
Regulation of developmental rate and germ cell proliferation in Caenorhabditis elegans by the p53 gene network
-
Derry W.B., Bierings R., van Iersel M., Satkunendran T., Reinke V., Rothman J.H. Regulation of developmental rate and germ cell proliferation in Caenorhabditis elegans by the p53 gene network. Cell Death Differ. 2007, 14(4):662-670.
-
(2007)
Cell Death Differ.
, vol.14
, Issue.4
, pp. 662-670
-
-
Derry, W.B.1
Bierings, R.2
van Iersel, M.3
Satkunendran, T.4
Reinke, V.5
Rothman, J.H.6
-
9
-
-
0035913975
-
Caenorhabditis elegans p53: role in apoptosis, meiosis, and stress resistance
-
Derry W.B., Putzke A.P., Rothman J.H. Caenorhabditis elegans p53: role in apoptosis, meiosis, and stress resistance. Science 2001, 294(5542):591-595.
-
(2001)
Science
, vol.294
, Issue.5542
, pp. 591-595
-
-
Derry, W.B.1
Putzke, A.P.2
Rothman, J.H.3
-
10
-
-
48249156188
-
Mitochondrial disorders in the nervous system
-
DiMauro S., Schon E.A. Mitochondrial disorders in the nervous system. Annu. Rev. Neurosci. 2008, 31:91-123.
-
(2008)
Annu. Rev. Neurosci.
, vol.31
, pp. 91-123
-
-
DiMauro, S.1
Schon, E.A.2
-
11
-
-
33846000687
-
P53 suppresses the Nrf2-dependent transcription of antioxidant response genes
-
Faraonio R., Vergara P., Di Marzo D., Pierantoni M.G., Napolitano M., Russo T., Cimino F. p53 suppresses the Nrf2-dependent transcription of antioxidant response genes. J. Biol. Chem. 2006, 281(52):39776-39784.
-
(2006)
J. Biol. Chem.
, vol.281
, Issue.52
, pp. 39776-39784
-
-
Faraonio, R.1
Vergara, P.2
Di Marzo, D.3
Pierantoni, M.G.4
Napolitano, M.5
Russo, T.6
Cimino, F.7
-
12
-
-
0035515923
-
Mitochondrial electron transport is a key determinant of life span in Caenorhabditis elegans
-
Feng J., Bussiere F., Hekimi S. Mitochondrial electron transport is a key determinant of life span in Caenorhabditis elegans. Dev. Cell 2001, 1(5):633-644.
-
(2001)
Dev. Cell
, vol.1
, Issue.5
, pp. 633-644
-
-
Feng, J.1
Bussiere, F.2
Hekimi, S.3
-
13
-
-
44049084453
-
The SCF FSN-1 ubiquitin ligase controls germline apoptosis through CEP-1/p53 in C. elegans
-
Gao M.X., Liao E.H., Yu B., Wang Y., Zhen M., Derry W.B. The SCF FSN-1 ubiquitin ligase controls germline apoptosis through CEP-1/p53 in C. elegans. Cell Death Differ. 2008, 15(6):1054-1062.
-
(2008)
Cell Death Differ.
, vol.15
, Issue.6
, pp. 1054-1062
-
-
Gao, M.X.1
Liao, E.H.2
Yu, B.3
Wang, Y.4
Zhen, M.5
Derry, W.B.6
-
14
-
-
0036839455
-
Biogenesis of iron-sulfur proteins in eukaryotes: components, mechanism and pathology
-
Gerber J., Lill R. Biogenesis of iron-sulfur proteins in eukaryotes: components, mechanism and pathology. Mitochondrion 2002, 2(1-2):71-86.
-
(2002)
Mitochondrion
, vol.2
, Issue.1-2
, pp. 71-86
-
-
Gerber, J.1
Lill, R.2
-
15
-
-
48549085585
-
Transcriptional profiling in C. elegans suggests DNA damage dependent apoptosis as an ancient function of the p53 family
-
Greiss S., Schumacher B., Grandien K., Rothblatt J., Gartner A. Transcriptional profiling in C. elegans suggests DNA damage dependent apoptosis as an ancient function of the p53 family. BMC Genomics 2008, 9:334.
-
(2008)
BMC Genomics
, vol.9
, pp. 334
-
-
Greiss, S.1
Schumacher, B.2
Grandien, K.3
Rothblatt, J.4
Gartner, A.5
-
16
-
-
39849104918
-
Selection and validation of a set of reliable reference genes for quantitative sod gene expression analysis in C. elegans
-
Hoogewijs D., Houthoofd K., Matthijssens F., Vandesompele J., Vanfleteren J.R. Selection and validation of a set of reliable reference genes for quantitative sod gene expression analysis in C. elegans. BMC Mol. Biol. 2008, 9:9.
-
(2008)
BMC Mol. Biol.
, vol.9
, pp. 9
-
-
Hoogewijs, D.1
Houthoofd, K.2
Matthijssens, F.3
Vandesompele, J.4
Vanfleteren, J.R.5
-
17
-
-
3142642685
-
Structural differences in the DNA binding domains of human p53 and its C. elegans ortholog Cep-1
-
Huyen Y., Jeffrey P.D., Derry W.B., Rothman J.H., Pavletich N.P., Stavridi E.S., Halazonetis T.D. Structural differences in the DNA binding domains of human p53 and its C. elegans ortholog Cep-1. Structure 2004, 12(7):1237-1243.
-
(2004)
Structure
, vol.12
, Issue.7
, pp. 1237-1243
-
-
Huyen, Y.1
Jeffrey, P.D.2
Derry, W.B.3
Rothman, J.H.4
Pavletich, N.P.5
Stavridi, E.S.6
Halazonetis, T.D.7
-
18
-
-
20844449238
-
AMP-activated protein kinase induces a p53-dependent metabolic checkpoint
-
Jones R.G., Plas D.R., Kubek S., Buzzai M., Mu J., Xu Y., Birnbaum M.J., Thompson C.B. AMP-activated protein kinase induces a p53-dependent metabolic checkpoint. Mol. Cell 2005, 18(3):283-293.
-
(2005)
Mol. Cell
, vol.18
, Issue.3
, pp. 283-293
-
-
Jones, R.G.1
Plas, D.R.2
Kubek, S.3
Buzzai, M.4
Mu, J.5
Xu, Y.6
Birnbaum, M.J.7
Thompson, C.B.8
-
19
-
-
38149092669
-
Proteasomal dysfunction activates the transcription factor SKN-1 and produces a selective oxidative-stress response in Caenorhabditis elegans
-
Kahn N.W., Rea S.L., Moyle S., Kell A., Johnson T.E. Proteasomal dysfunction activates the transcription factor SKN-1 and produces a selective oxidative-stress response in Caenorhabditis elegans. Biochem. J. 2008, 409(1):205-213.
-
(2008)
Biochem. J.
, vol.409
, Issue.1
, pp. 205-213
-
-
Kahn, N.W.1
Rea, S.L.2
Moyle, S.3
Kell, A.4
Johnson, T.E.5
-
20
-
-
0038725897
-
Genome-wide RNAi screening in Caenorhabditis elegans
-
Kamath R.S., Ahringer J. Genome-wide RNAi screening in Caenorhabditis elegans. Methods 2003, 30(4):313-321.
-
(2003)
Methods
, vol.30
, Issue.4
, pp. 313-321
-
-
Kamath, R.S.1
Ahringer, J.2
-
21
-
-
33749265843
-
The structures of frataxin oligomers reveal the mechanism for the delivery and detoxification of iron
-
Karlberg T., Schagerlof U., Gakh O., Park S., Ryde U., Lindahl M., Leath K., Garman E., Isaya G., Al-Karadaghi S. The structures of frataxin oligomers reveal the mechanism for the delivery and detoxification of iron. Structure 2006, 14(10):1535-1546.
-
(2006)
Structure
, vol.14
, Issue.10
, pp. 1535-1546
-
-
Karlberg, T.1
Schagerlof, U.2
Gakh, O.3
Park, S.4
Ryde, U.5
Lindahl, M.6
Leath, K.7
Garman, E.8
Isaya, G.9
Al-Karadaghi, S.10
-
22
-
-
33745028132
-
The role of mitochondria in inherited neurodegenerative diseases
-
Kwong J.Q., Beal M.F., Manfredi G. The role of mitochondria in inherited neurodegenerative diseases. J. Neurochem. 2006, 97(6):1659-1675.
-
(2006)
J. Neurochem.
, vol.97
, Issue.6
, pp. 1659-1675
-
-
Kwong, J.Q.1
Beal, M.F.2
Manfredi, G.3
-
23
-
-
0037009846
-
The role of iron in cell cycle progression and the proliferation of neoplastic cells
-
Le N.T., Richardson D.R. The role of iron in cell cycle progression and the proliferation of neoplastic cells. Biochim. Biophys. Acta 2002, 1603(1):31-46.
-
(2002)
Biochim. Biophys. Acta
, vol.1603
, Issue.1
, pp. 31-46
-
-
Le, N.T.1
Richardson, D.R.2
-
24
-
-
33745149291
-
P53 regulates mitochondrial respiration
-
Matoba S., Kang J.G., Patino W.D., Wragg A., Boehm M., Gavrilova O., Hurley P.J., Bunz F., Hwang P.M. p53 regulates mitochondrial respiration. Science 2006, 312(5780):1650-1653.
-
(2006)
Science
, vol.312
, Issue.5780
, pp. 1650-1653
-
-
Matoba, S.1
Kang, J.G.2
Patino, W.D.3
Wragg, A.4
Boehm, M.5
Gavrilova, O.6
Hurley, P.J.7
Bunz, F.8
Hwang, P.M.9
-
25
-
-
50149097809
-
A complex barcode underlies the heterogeneous response of p53 to stress
-
Murray-Zmijewski F., Slee E.A., Lu X. A complex barcode underlies the heterogeneous response of p53 to stress. Nat. Rev. Mol. Cell Biol. 2008, 9(9):702-712.
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, Issue.9
, pp. 702-712
-
-
Murray-Zmijewski, F.1
Slee, E.A.2
Lu, X.3
-
26
-
-
67649402187
-
The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress
-
Nguyen T., Nioi P., Pickett C.B. The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress. J. Biol. Chem. 2009, 284(20):13291-13295.
-
(2009)
J. Biol. Chem.
, vol.284
, Issue.20
, pp. 13291-13295
-
-
Nguyen, T.1
Nioi, P.2
Pickett, C.B.3
-
27
-
-
34547220908
-
Structural evolution of C-terminal domains in the p53 family
-
Ou H.D., Lohr F., Vogel V., Mantele W., Dotsch V. Structural evolution of C-terminal domains in the p53 family. EMBO J. 2007, 26(14):3463-3473.
-
(2007)
EMBO J.
, vol.26
, Issue.14
, pp. 3463-3473
-
-
Ou, H.D.1
Lohr, F.2
Vogel, V.3
Mantele, W.4
Dotsch, V.5
-
28
-
-
64249161639
-
Impaired nuclear Nrf2 translocation undermines the oxidative stress response in Friedreich ataxia
-
Paupe V., Dassa E.P., Goncalves S., Auchere F., Lonn M., Holmgren A., Rustin P. Impaired nuclear Nrf2 translocation undermines the oxidative stress response in Friedreich ataxia. PLoS ONE 2009, 4(1):e4253.
-
(2009)
PLoS ONE
, vol.4
, Issue.1
-
-
Paupe, V.1
Dassa, E.P.2
Goncalves, S.3
Auchere, F.4
Lonn, M.5
Holmgren, A.6
Rustin, P.7
-
29
-
-
35648947912
-
Relationship between mitochondrial electron transport chain dysfunction, development, and life extension in Caenorhabditis elegans
-
Rea S.L., Ventura N., Johnson T.E. Relationship between mitochondrial electron transport chain dysfunction, development, and life extension in Caenorhabditis elegans. PLoS Biol. 2007, 5(10):e259.
-
(2007)
PLoS Biol.
, vol.5
, Issue.10
-
-
Rea, S.L.1
Ventura, N.2
Johnson, T.E.3
-
30
-
-
13544267521
-
Translational repression of C. elegans p53 by GLD-1 regulates DNA damage-induced apoptosis
-
Schumacher B., Hanazawa M., Lee M.H., Nayak S., Volkmann K., Hofmann E.R., Hengartner M., Schedl T., Gartner A. Translational repression of C. elegans p53 by GLD-1 regulates DNA damage-induced apoptosis. Cell 2005, 120(3):357-368.
-
(2005)
Cell
, vol.120
, Issue.3
, pp. 357-368
-
-
Schumacher, B.1
Hanazawa, M.2
Lee, M.H.3
Nayak, S.4
Volkmann, K.5
Hofmann, E.R.6
Hengartner, M.7
Schedl, T.8
Gartner, A.9
-
31
-
-
0035975986
-
The C. elegans homolog of the p53 tumor suppressor is required for DNA damage-induced apoptosis
-
Schumacher B., Hofmann K., Boulton S., Gartner A. The C. elegans homolog of the p53 tumor suppressor is required for DNA damage-induced apoptosis. Curr. Biol. 2001, 11(21):1722-1727.
-
(2001)
Curr. Biol.
, vol.11
, Issue.21
, pp. 1722-1727
-
-
Schumacher, B.1
Hofmann, K.2
Boulton, S.3
Gartner, A.4
-
32
-
-
44649141966
-
Regulation of autophagy by cytoplasmic p53
-
Tasdemir E., Maiuri M.C., Galluzzi L., Vitale I., Djavaheri-Mergny M., D'Amelio M., Criollo A., Morselli E., Zhu C., Harper F., Nannmark U., Samara C., Pinton P., Vicencio J.M., Carnuccio R., Moll U.M., Madeo F., Paterlini-Brechot P., Rizzuto R., Szabadkai G., Pierron G., Blomgren K., Tavernarakis N., Codogno P., Cecconi F., Kroemer G. Regulation of autophagy by cytoplasmic p53. Nat. Cell Biol. 2008, 10(6):676-687.
-
(2008)
Nat. Cell Biol.
, vol.10
, Issue.6
, pp. 676-687
-
-
Tasdemir, E.1
Maiuri, M.C.2
Galluzzi, L.3
Vitale, I.4
Djavaheri-Mergny, M.5
D'Amelio, M.6
Criollo, A.7
Morselli, E.8
Zhu, C.9
Harper, F.10
Nannmark, U.11
Samara, C.12
Pinton, P.13
Vicencio, J.M.14
Carnuccio, R.15
Moll, U.M.16
Madeo, F.17
Paterlini-Brechot, P.18
Rizzuto, R.19
Szabadkai, G.20
Pierron, G.21
Blomgren, K.22
Tavernarakis, N.23
Codogno, P.24
Cecconi, F.25
Kroemer, G.26
more..
-
33
-
-
0037129827
-
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
-
RESEARCH0034
-
Vandesompele J., De Preter K., Pattyn F., Poppe B., Van Roy N., De Paepe A., Speleman F. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol. 2002, 3(7). RESEARCH0034.
-
(2002)
Genome Biol.
, vol.3
, Issue.7
-
-
Vandesompele, J.1
De Preter, K.2
Pattyn, F.3
Poppe, B.4
Van Roy, N.5
De Paepe, A.6
Speleman, F.7
-
34
-
-
22144462536
-
Reduced expression of frataxin extends the lifespan of Caenorhabditis elegans
-
Ventura N., Rea S., Henderson S.T., Condo I., Johnson T.E., Testi R. Reduced expression of frataxin extends the lifespan of Caenorhabditis elegans. Aging Cell 2005, 4(2):109-112.
-
(2005)
Aging Cell
, vol.4
, Issue.2
, pp. 109-112
-
-
Ventura, N.1
Rea, S.2
Henderson, S.T.3
Condo, I.4
Johnson, T.E.5
Testi, R.6
-
35
-
-
34249711285
-
Caenorhabditis elegans mitochondrial mutants as an investigative tool to study human neurodegenerative diseases associated with mitochondrial dysfunction
-
Ventura N., Rea S.L. Caenorhabditis elegans mitochondrial mutants as an investigative tool to study human neurodegenerative diseases associated with mitochondrial dysfunction. Biotechnol. J. 2007, 2(5):584-595.
-
(2007)
Biotechnol. J.
, vol.2
, Issue.5
, pp. 584-595
-
-
Ventura, N.1
Rea, S.L.2
-
36
-
-
67651174517
-
P53/CEP-1 increases or decreases lifespan, depending on level of mitochondrial bioenergetic stress
-
Ventura N., Rea S.L., Schiavi A., Torgovnick A., Testi R., Johnson T.E. p53/CEP-1 increases or decreases lifespan, depending on level of mitochondrial bioenergetic stress. Aging Cell 2009, 8(4):380-393.
-
(2009)
Aging Cell
, vol.8
, Issue.4
, pp. 380-393
-
-
Ventura, N.1
Rea, S.L.2
Schiavi, A.3
Torgovnick, A.4
Testi, R.5
Johnson, T.E.6
-
37
-
-
33751437445
-
Long-lived C. elegans mitochondrial mutants as a model for human mitochondrial-associated diseases
-
Ventura N., Rea S.L., Testi R. Long-lived C. elegans mitochondrial mutants as a model for human mitochondrial-associated diseases. Exp. Gerontol. 2006, 41(10):974-991.
-
(2006)
Exp. Gerontol.
, vol.41
, Issue.10
, pp. 974-991
-
-
Ventura, N.1
Rea, S.L.2
Testi, R.3
-
39
-
-
23844558266
-
A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine
-
Wallace D.C. A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine. Annu. Rev. Genet. 2005, 39:359-407.
-
(2005)
Annu. Rev. Genet.
, vol.39
, pp. 359-407
-
-
Wallace, D.C.1
-
40
-
-
0033054177
-
The Friedreich's ataxia mutation confers cellular sensitivity to oxidant stress which is rescued by chelators of iron and calcium and inhibitors of apoptosis
-
Wong A., Yang J., Cavadini P., Gellera C., Lonnerdal B., Taroni F., Cortopassi G. The Friedreich's ataxia mutation confers cellular sensitivity to oxidant stress which is rescued by chelators of iron and calcium and inhibitors of apoptosis. Hum. Mol. Genet. 1999, 8(3):425-430.
-
(1999)
Hum. Mol. Genet.
, vol.8
, Issue.3
, pp. 425-430
-
-
Wong, A.1
Yang, J.2
Cavadini, P.3
Gellera, C.4
Lonnerdal, B.5
Taroni, F.6
Cortopassi, G.7
-
41
-
-
0004291817
-
-
Cold Spring Harbor Laboratory, New York, W.B. Wood (Ed.)
-
The Nematode Caenorhabditis elegans 1988, Cold Spring Harbor Laboratory, New York. W.B. Wood (Ed.).
-
(1988)
The Nematode Caenorhabditis elegans
-
-
|