Unopposed mitochondrial fission leads to severe lifespan shortening

Cell Cycle

Volumn 10, Issue 18, 2011, Pages 3105-3110

  Scheckhuber, Christian Q ^b   Wanger, Ruth A ^c   Mignat, Cora A ^a   Osiewacz, Heinz D ^a  

^a GOETHE UNIVERSITY   (Germany)

^b UNIVERSITY OF GRONINGEN   (Netherlands)

^c UNIVERSITY HOSPITAL FRANKFURT   (Germany)

Author keywords

Ageing; Chronological lifespan; Fission; Fusion; Mgm1p; Mitochondrial dynamics; OPA1; Replicative lifespan; S. cerevisiae; Yeast

Indexed keywords

HYDROGEN PEROXIDE; MEMBRANE FUSION PROTEIN; MEMBRANE PROTEIN; MGM1 PROTEIN; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL AGING; CELL INTERACTION; CELL PROTECTION; CELL STRUCTURE; CELL SURVIVAL; CELLULAR DISTRIBUTION; CONTROLLED STUDY; GENE DELETION; GENOTYPE; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; MUTANT; NONHUMAN; OXIDATIVE STRESS; PHENOTYPE; SACCHAROMYCES CEREVISIAE;

MAMMALIA;

EID: 80052879466     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.10.18.17196     Document Type: Article

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