Reduced AMPK-ACC and mTOR signaling in muscle from older men, and effect of resistance exercise

Mechanisms of Ageing and Development

Volumn 133, Issue 11-12, 2012, Pages 655-664

  Li, Mengyao ^a,b,c   Verdijk, Lex B ^d   Sakamoto, Kei ^e   Ely, Brian ^a,b,c   van Loon, Luc J C ^d   Musi, Nicolas ^a,b,c  

^a SOUTH TEXAS VETERANS HEALTH CARE SYSTEM   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c Texas Diabetes Institute   (United States)

^d MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^e EPFL   (Switzerland)

Author keywords

Aging; AMPK; MTOR; Resistance exercise; Skeletal muscle

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; GLUCOSE; HEMOGLOBIN A1C; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE ALPHA1; INSULIN; MAMMALIAN TARGET OF RAPAMYCIN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BODY FAT; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME SUBSTRATE; HUMAN; HUMAN TISSUE; LEAN BODY WEIGHT; MALE; MUSCLE STRENGTH; PHYSICAL ACTIVITY; PRIORITY JOURNAL; QUADRICEPS FEMORIS MUSCLE; RESISTANCE TRAINING; SIGNAL TRANSDUCTION; UPREGULATION;

ACETYL-COA CARBOXYLASE; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; AMP-ACTIVATED PROTEIN KINASES; BIOPSY; BODY WEIGHT; EXERCISE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MALE; MIDDLE AGED; MUSCLES; PHOSPHORYLATION; PROTEIN KINASES; RESISTANCE TRAINING; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

MAMMALIA;

EID: 84870756683     PISSN: 00476374     EISSN: 18726216     Source Type: Journal    
DOI: 10.1016/j.mad.2012.09.001     Document Type: Article

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