Control of skin cancer by the circadian rhythm

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 46, 2011, Pages 18790-18795

  Gaddameedhi, Shobhan ^a   Selby, Christopher P ^a   Kaufmann, William K ^a   Smart, Robert C ^b   Sancar, Aziz ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

Circadian clock; Cryptochrome; Sunbathing; Tanning salons

Indexed keywords

DNA; XERODERMA PIGMENTOSUM GROUP A PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CONTROL; CARCINOGENICITY; CIRCADIAN RHYTHM; CONTROLLED STUDY; DNA DAMAGE; EXCISION REPAIR; LATENT PERIOD; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKIN CANCER; SQUAMOUS CELL CARCINOMA; SUNLIGHT; ULTRAVIOLET RADIATION; UNITED STATES;

ANIMALS; CARCINOMA, SQUAMOUS CELL; CIRCADIAN RHYTHM; DISEASE MODELS, ANIMAL; DNA DAMAGE; DNA REPAIR; HUMANS; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; SKIN; SKIN NEOPLASMS; SUNLIGHT; TIME FACTORS; XERODERMA PIGMENTOSUM GROUP A PROTEIN;

MUS;

EID: 81755163584     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1115249108     Document Type: Article

References (37)

1. American Cancer Society (2008) Cancer Facts and Figures. Available at http://www.cancer.org/Research/CancerFactsFigures/cancer-facts-figures2008. Accessed May 5, 2011.
2. Fisher DE, James WD (2010) Indoor tanning - science, behavior, and policy. N Engl J Med 363:901-903.
3. Bowden GT (2004) Prevention of non-melanoma skin cancer by targeting ultraviolet- B-light signalling. Nat Rev Cancer 4:23-35.
4. Narayanan DL, Saladi RN, Fox JL (2010) Ultraviolet radiation and skin cancer. Int J Dermatol 49:978-986.
5. Jans J, et al. (2005) Powerful skin cancer protection by a CPD-photolyase transgene. Curr Biol 15:105-115.
6. Brash DE, et al. (1991) A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma. Proc Natl Acad Sci USA 88:10124-10128. (Pubitemid 21915787)
7. Cleaver JE (1968) Defective repair replication of DNA in xeroderma pigmentosum. Nature 218:652-656.
8. Kraemer KH, Lee MM, Scotto J (1987) Xeroderma pigmentosum. Cutaneous, ocular, and neurologic abnormalities in 830 published cases. Arch Dermatol 123:241-250. (Pubitemid 17002499)
9. Reardon JT, Sancar A (2005) Nucleotide excision repair. Prog Nucleic Acid Res Mol Biol 79:183-235. (Pubitemid 43583902)
10. Mu D, et al. (1995) Reconstitution of human DNA repair excision nuclease in a highly defined system. J Biol Chem 270:2415-2418.
11. Kang TH, Reardon JT, Kemp M, Sancar A (2009) Circadian oscillation of nucleotide excision repair in mammalian brain. Proc Natl Acad Sci USA 106:2864-2867.
12. Kang TH, Lindsey-Boltz LA, Reardon JT, Sancar A (2010) Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase. Proc Natl Acad Sci USA 107:4890-4895.
13. Reppert SM, Weaver DR (2002) Coordination of circadian timing in mammals. Nature 418:935-941. (Pubitemid 34976023)
14. Lowrey PL, Takahashi JS (2004) Mammalian circadian biology: Elucidating genome-wide levels of temporal organization. Annu Rev Genomics Hum Genet 5:407-441. (Pubitemid 39362752)
15. Sahar S, Sassone-Corsi P (2009) Metabolism and cancer: The circadian clock connection. Nat Rev Cancer 9:886-896.
16. Antoch MP, Kondratov RV (2010) Circadian proteins and genotoxic stress response. Circ Res 106:68-78.
17. Benavides F, Oberyszyn TM, VanBuskirk AM, Reeve VE, Kusewitt DF (2009) The hairless mouse in skin research. J Dermatol Sci 53:10-18.
18. de Gruijl FR, Forbes PD (1995) UV-induced skin cancer in a hairless mouse model. Bioessays 17:651-660.
19. Kvam E, Tyrrell RM (1997) Induction of oxidative DNA base damage in human skin cells by UV and near visible radiation. Carcinogenesis 18:2379-2384. (Pubitemid 28134653)
20. Wani AA, D'Ambrosio SM, Alvi NK (1987) Quantitation of pyrimidine dimers by immunoslot blot following sublethal UV-irradiation of human cells. Photochem Photobiol 46:477-482.
21. Mitchell DL (1988) The relative cytotoxicity of (6-4) photoproducts and cyclobutane dimers in mammalian cells. Photochem Photobiol 48:51-57.
22. Gaddameedhi S, et al. (2010) Similar nucleotide excision repair capacity in melanocytes and melanoma cells. Cancer Res 70:4922-4930.
23. Gao S, Drouin R, Holmquist GP (1994) DNA repair rates mapped along the human PGK1 gene at nucleotide resolution. Science 263:1438-1440. (Pubitemid 24137832)
24. Vitaterna MH, et al. (1999) Differential regulation of mammalian period genes and circadian rhythmicity by cryptochromes 1 and 2. Proc Natl Acad Sci USA 96:12114-12119. (Pubitemid 29502867)
25. van der Horst GT, et al. (1999) Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms. Nature 398:627-630.
26. Tanioka M, et al. (2009) Molecular clocks in mouse skin. J Invest Dermatol 129:1225-1231.
27. Brown WR (1991) A review and mathematical analysis of circadian rhythms in cell proliferation in mouse, rat, and human epidermis. J Invest Dermatol 97:273-280.
28. Bjarnason GA, et al. (2001) Circadian expression of clock genes in human oral mucosa and skin: Association with specific cell-cycle phases. Am J Pathol 158:1793-1801. (Pubitemid 32422944)
29. Thompson EA, et al. (2011) C/EBPα expression is downregulated in human nonmelanoma skin cancers and inactivation of C/EBPα confers susceptibility to UVB-induced skin squamous cell carcinomas. J Invest Dermatol 131:1339-1346.
30. Ueda J, Saito H, Watanabe H, Evers BM (2005) Novel and quantitative DNA dotblotting method for assessment of in vivo proliferation. Am J Physiol Gastrointest Liver Physiol 288:G842-G847. (Pubitemid 40388196)
31. Hastings MH, Reddy AB, Maywood ES (2003) A clockwork web: Circadian timing in brain and periphery, in health and disease. Nat Rev Neurosci 4:649-661. (Pubitemid 37280160)
32. Levi F, Schibler U (2007) Circadian rhythms: Mechanisms and therapeutic implications. Annu Rev Pharmacol Toxicol 47:593-628.
33. de Vries A, et al. (1998) XPA-deficiency in hairless mice causes a shift in skin tumor types and mutational target genes after exposure to low doses of U.V.B. Oncogene 16:2205-2212.
34. Zanello SB, Jackson DM, HolickMF (2000) Expression of the circadian clock genes clock and period1 in human skin. J Invest Dermatol 115:757-760.
35. Akashi M, et al. (2010) Noninvasive method for assessing the human circadian clock using hair follicle cells. Proc Natl Acad Sci USA 107:15643-15648.
36. Thomas-Ahner JM, et al. (2007) Gender differences in UVB-induced skin carcinogenesis, inflammation, and DNA damage. Cancer Res 67:3468-3474. (Pubitemid 46724888)
37. House JS, Zhu S, Ranjan R, Linder K, Smart RC (2010) C/EBPalpha and C/EBPbeta are required for Sebocyte differentiation and stratified squamous differentiation in adult mouse skin. PLoS ONE 5:e9837.