Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21CIP1, but not p16INK4a

Molecular Cell

Volumn 14, Issue 4, 2004, Pages 501-513

  Herbig, Utz ^a   Jobling, Wendy A ^a   Chen, Benjamin P C ^b   Chen, David J ^b   Sedivy, John M ^a  

^a BROWN UNIVERSITY   (United States)

^b LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; PROTEIN P16; PROTEIN P21; PROTEIN P53;

ARTICLE; CELL CULTURE; CELL CYCLE; CELL CYCLE G2 PHASE; DNA DAMAGE; FIBROBLAST; HUMAN; HUMAN CELL; SENESCENCE; TELOMERE; UPREGULATION;

CELL AGING; CELL CYCLE PROTEINS; CELL DEATH; CELL LINE; CYCLIN-DEPENDENT KINASE INHIBITOR P16; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; DNA DAMAGE; DNA-BINDING PROTEINS; G1 PHASE; G2 PHASE; GENES, CDC; HUMANS; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; STRESS; TELOMERE; TELOMERIC REPEAT BINDING PROTEIN 2; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS; UP-REGULATION;

EID: 2442511752     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(04)00256-4     Document Type: Article

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